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29  structures 1529  species 3  interactions 3849  sequences 42  architectures

Clan: ALDC (CL0615)

Summary

ALDC superfamily Add an annotation

This superfamiy includes the enzyme acetolactate decarboxylase as well as s number of other uncharacterised presumed enzymes. The core of this superfamily is an alpha/beta domain with a highly curved beta sheet that often has a zinc cordination site with three histidine residues.

This clan contains 3 families and the total number of domains in the clan is 3849. The clan was built by A Bateman.

Literature references

  1. Marlow VA, Rea D, Najmudin S, Wills M, Fulop V;, ACS Chem Biol. 2013;8:2339-2344.: Structure and mechanism of acetolactate decarboxylase. PUBMED:23985082 EPMC:23985082

Members

This clan contains the following 3 member families:

AAL_decarboxy DUF1907 DUF296

External database links

Domain organisation

Below is a listing of the unique domain organisations or architectures from this clan. More...

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Alignments

The table below shows the number of occurrences of each domain throughout the sequence database. More...

Pfam family Num. domains Alignment
DUF296 (PF03479) 2744 (71.3%) View
AAL_decarboxy (PF03306) 713 (18.5%) View
DUF1907 (PF08925) 392 (10.2%) View
Total: 3 Total: 3849 Clan alignment
 

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Family relationships

This diagram shows the relationships between members of this clan. More...

Species distribution

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This tree shows the occurrence of the domains in this clan across different species. More...

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Interactions

There are 3 interactions for this clan. More...

Interacting families
A B
AAL_decarboxy AAL_decarboxy
DUF1907 DUF1907
DUF296 DUF296

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between the Pfam families in this clan, the corresponding UniProt entries, and the region of the three-dimensional structures that are available for that sequence.

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