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248  structures 8083  species 10  interactions 101709  sequences 2884  architectures

Clan: AMP-binding_C (CL0531)


AMP-binding enzyme C-terminal domain superfamily Add an annotation

This superfamily contains domains found at the C-terminus of AMP-binding enzyme.

This clan contains 2 families and the total number of domains in the clan is 101709. The clan was built by R Eberhardt.


This clan contains the following 2 member families:

AMP-binding_C AMP-binding_C_2

Domain organisation

Below is a listing of the unique domain organisations or architectures from this clan. More...

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The table below shows the number of occurrences of each domain throughout the sequence database. More...

Pfam family Num. domains Alignment
AMP-binding_C (PF13193) 97760 (96.1%) View
AMP-binding_C_2 (PF14535) 3949 (3.9%) View
Total: 2 Total: 101709 Clan alignment

Please note: Clan alignments can be very large and can cause problems for some browsers. Read the note above before viewing.

Family relationships

This diagram shows the relationships between members of this clan. More...

Species distribution

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This tree shows the occurrence of the domains in this clan across different species. More...



There are 10 interactions for this clan. More...

Interacting families
AMP-binding AMP-binding_C
AMP-binding_C AMP-binding
AMP-binding_C_2 AMP-binding
Condensation AMP-binding_C
PP-binding AMP-binding_C
SIR2 AMP-binding_C


For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between the Pfam families in this clan, the corresponding UniProt entries, and the region of the three-dimensional structures that are available for that sequence.

Loading structure mapping...