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170  structures 8495  species 8  interactions 25820  sequences 168  architectures

Clan: AMP_N-like (CL0356)


Creatinase/prolidase N-terminal domain superfamily Add an annotation

Bacterial amino-peptidases and creatinases, where the fold is a ribonuclease H-like motif, are grouped in this superfamily.

This clan contains 4 families and the total number of domains in the clan is 25820. The clan was built by P Coggill.


This clan contains the following 4 member families:

AMP_N Creatinase_N Creatinase_N_2 FACT-Spt16_Nlob

External database links

Domain organisation

Below is a listing of the unique domain organisations or architectures from this clan. More...

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The table below shows the number of occurrences of each domain throughout the sequence database. More...

Pfam family Num. domains Alignment
Creatinase_N (PF01321) 13985 (54.2%) View
AMP_N (PF05195) 6341 (24.6%) View
Creatinase_N_2 (PF16189) 4306 (16.7%) View
FACT-Spt16_Nlob (PF14826) 1188 (4.6%) View
Total: 4 Total: 25820 Clan alignment

Please note: Clan alignments can be very large and can cause problems for some browsers. Read the note above before viewing.

Family relationships

This diagram shows the relationships between members of this clan. More...

Species distribution

Tree controls


This tree shows the occurrence of the domains in this clan across different species. More...



There are 8 interactions for this clan. More...

Interacting families
Creatinase_N Creatinase_N
FACT-Spt16_Nlob Peptidase_M24
Peptidase_M24 AMP_N


For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between the Pfam families in this clan, the corresponding UniProt entries, and the region of the three-dimensional structures that are available for that sequence.

Loading structure mapping...