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0  structures 303  species 0  interactions 446  sequences 11  architectures

Clan: APCOP-app_sub (CL0545)


Clathrin (AP) and COPI appendage platform subdomain Add an annotation

This superfamily is characterised by subdomains from the clathrin and coatomer appendages. The superfamily possesses a single protein/protein interaction site that in yeast binds to the ARFGAP Glo3p, and in mammalian gamma-COP binds to a Glo3p orthologue, ARFGAP2 [1].

This clan contains 2 families and the total number of domains in the clan is 446. The clan was built by P Coggill.

Literature references

  1. Watson PJ, Frigerio G, Collins BM, Duden R, Owen DJ; , Traffic. 2004;5:79-88.: Gamma-COP appendage domain - structure and function. PUBMED:14690497 EPMC:14690497


This clan contains the following 2 member families:

AP4E_app_platf Coatomer_b_Cpla

External database links

Domain organisation

Below is a listing of the unique domain organisations or architectures from this clan. More...

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The table below shows the number of occurrences of each domain throughout the sequence database. More...

Pfam family Num. domains Alignment
Coatomer_b_Cpla (PF14806) 371 (83.2%) View
AP4E_app_platf (PF14807) 75 (16.8%) View
Total: 2 Total: 446 Clan alignment

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Family relationships

This diagram shows the relationships between members of this clan. More...

Species distribution

Tree controls


This tree shows the occurrence of the domains in this clan across different species. More...