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50  structures 3586  species 3  interactions 11690  sequences 24  architectures

Clan: AbrB (CL0132)


AbrB/MraZ DNA-binding domain Add an annotation

This superfamily includes the DNA-binding domain of AbrB as well as the presumed DNA-binding protein MraZ (per. comm. A Andreeva and A Murzin).

This clan contains 3 families and the total number of domains in the clan is 11690. The clan was built by A Bateman.


This clan contains the following 3 member families:

Antitoxin-MazE MraZ SymE_toxin

External database links

Domain organisation

Below is a listing of the unique domain organisations or architectures from this clan. More...

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The table below shows the number of occurrences of each domain throughout the sequence database. More...

Pfam family Num. domains Alignment
MraZ (PF02381) 5872 (50.2%) View
Antitoxin-MazE (PF04014) 4979 (42.6%) View
SymE_toxin (PF08845) 839 (7.2%) View
Total: 3 Total: 11690 Clan alignment

Please note: Clan alignments can be very large and can cause problems for some browsers. Read the note above before viewing.

Family relationships

This diagram shows the relationships between members of this clan. More...

Species distribution

Tree controls


This tree shows the occurrence of the domains in this clan across different species. More...



There are 3 interactions for this clan. More...

Interacting families
Antitoxin-MazE PemK
MraZ MraZ


For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between the Pfam families in this clan, the corresponding UniProt entries, and the region of the three-dimensional structures that are available for that sequence.

Loading structure mapping...