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49  structures 15972  species 6  interactions 44355  sequences 27  architectures

Clan: AbrB (CL0132)

Summary

AbrB/MraZ DNA-binding domain Add an annotation

This superfamily includes the DNA-binding domain of AbrB as well as the presumed DNA-binding protein MraZ (per. comm. A Andreeva and A Murzin).

This clan contains 4 families and the total number of domains in the clan is 44355. The clan was built by A Bateman.

Members

This clan contains the following 4 member families:

AbrB-like MazE_antitoxin MraZ PrlF_antitoxin

External database links

Domain organisation

Below is a listing of the unique domain organisations or architectures from this clan. More...

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Alignments

The table below shows the number of occurrences of each domain throughout the sequence database. More...

Pfam family Num. domains Alignment
MraZ (PF02381) 28317 (63.8%) View
MazE_antitoxin (PF04014) 13743 (31.0%) View
PrlF_antitoxin (PF15937) 1979 (4.5%) View
AbrB-like (PF14250) 316 (0.7%) View
Total: 4 Total: 44355 Clan alignment
 

Please note: Clan alignments can be very large and can cause problems for some browsers. Read the note above before viewing.

Family relationships

This diagram shows the relationships between members of this clan. More...

Species distribution

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This tree shows the occurrence of the domains in this clan across different species. More...

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Interactions

There are 6 interactions for this clan. More...

Interacting families
A B
MazE_antitoxin MazE_antitoxin
PIN
MraZ MraZ
PemK_toxin MazE_antitoxin
PIN MazE_antitoxin
V-set MazE_antitoxin

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between the Pfam families in this clan, the corresponding UniProt entries, and the region of the three-dimensional structures that are available for that sequence.

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