Summary
N-acetyltransferase like
This clan contains families related to N-acetyltransferases. N-acetyltransferases catalyse the transfer of acetyl groups from acetyl-CoA to arylamines.
This clan contains 50 families and the total number of domains in the clan is 340693. The clan was built by J Mistry.
Literature references
- Chinenov Y; , Trends Biochem Sci 2002;27:115-117.: A second catalytic domain in the Elp3 histone acetyltransferases: a candidate for histone demethylase activity?. PUBMED:11893502 EPMC:11893502
- Kelley M, Vessey DA; , Biochem J 1992;288:315-317.: Structural comparison between the mitochondrial aralkyl-CoA and arylacetyl-CoA N-acyltransferases. PUBMED:1445276 EPMC:1445276
Members
This clan contains the following 50 member families:
Acetyltransf_1 Acetyltransf_10 Acetyltransf_13 Acetyltransf_15 Acetyltransf_16 Acetyltransf_17 Acetyltransf_18 Acetyltransf_19 Acetyltransf_3 Acetyltransf_4 Acetyltransf_5 Acetyltransf_6 Acetyltransf_7 Acetyltransf_8 Acetyltransf_9 Acetyltransf_CG AstA ATE_C ATE_N Autoind_synth CFAP61_N DUF1122 DUF1248 DUF1999 DUF5613 DUF5645 FemAB FemAB_like FR47 Gly_acyl_tr_C GNAT_acetyltr_2 GNAT_acetyltran GNAT_C GNAT_like HAT_KAT11 HlyC Leu_Phe_trans LPG_synthase_C MCD Mig-14 MOZ_SAS NAT NMT NMT_C NodA ODC_AZ PanZ Phage_T7_Gp13 Pho86 T_hemolysinExternal database links
CATH: | 3.40.630.30 |
SCOP: | 55729 |
Domain organisation
Below is a listing of the unique domain organisations or architectures from this clan. More...
Loading domain graphics...
Alignments
The table below shows the number of occurrences of each domain throughout the sequence database. More...
Pfam family | Num. domains | Alignment |
---|---|---|
ODC_AZ (PF02100) | 1581 (0.5%) | View |
AstA (PF04958) | 1476 (0.4%) | View |
Autoind_synth (PF00765) | 1432 (0.4%) | View |
Acetyltransf_16 (PF05301) | 1098 (0.3%) | View |
GNAT_acetyltran (PF12746) | 1082 (0.3%) | View |
Gly_acyl_tr_C (PF08444) | 760 (0.2%) | View |
CFAP61_N (PF16092) | 738 (0.2%) | View |
GNAT_like (PF18407) | 709 (0.2%) | View |
GNAT_C (PF18164) | 464 (0.1%) | View |
T_hemolysin (PF12261) | 330 (0.1%) | View |
HlyC (PF02794) | 284 (0.1%) | View |
PanZ (PF12568) | 240 (0.1%) | View |
Phage_T7_Gp13 (PF11090) | 130 (0.0%) | View |
NodA (PF02474) | 127 (0.0%) | View |
Mig-14 (PF07395) | 112 (0.0%) | View |
DUF5613 (PF18467) | 97 (0.0%) | View |
DUF1248 (PF06852) | 96 (0.0%) | View |
Acetyltransf_19 (PF18015) | 84 (0.0%) | View |
Pho86 (PF11124) | 81 (0.0%) | View |
DUF5645 (PF18713) | 69 (0.0%) | View |
DUF1122 (PF06557) | 41 (0.0%) | View |
DUF1999 (PF09390) | 26 (0.0%) | View |
Acetyltransf_15 (PF17013) | 24 (0.0%) | View |
Acetyltransf_9 (PF13527) | 0 (0.0%) | View |
Total: 50 | Total: 340693 |
Please note: Clan alignments can be very large and can cause problems for some browsers. Read the note above before viewing.
Family relationships
This diagram shows the relationships between members of this clan. More...
Species distribution
Tree controls
HideThis tree shows the occurrence of the domains in this clan across different species. More...
Loading...
Structures
For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between the Pfam families in this clan, the corresponding UniProt entries, and the region of the three-dimensional structures that are available for that sequence.
Loading structure mapping...