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165  structures 7760  species 6  interactions 15767  sequences 177  architectures

Clan: Acylphosphatase (CL0622)


Acylphosphatase/BLUF domain-like superfamily Add an annotation

This superfamily has a ferredoxin fold. It contains the BLUF domain and the acylphosphatase family.

This clan contains 4 families and the total number of domains in the clan is 15767. The clan was built by A Bateman.

Literature references

  1. Anderson S, Dragnea V, Masuda S, Ybe J, Moffat K, Bauer C;, Biochemistry. 2005;44:7998-8005.: Structure of a novel photoreceptor, the BLUF domain of AppA from Rhodobacter sphaeroides. PUBMED:15924418 EPMC:15924418


This clan contains the following 4 member families:

Acylphosphatase BLUF DUF1115 UPF0176_N

External database links

Domain organisation

Below is a listing of the unique domain organisations or architectures from this clan. More...

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The table below shows the number of occurrences of each domain throughout the sequence database. More...

Pfam family Num. domains Alignment
Acylphosphatase (PF00708) 7777 (49.3%) View
UPF0176_N (PF17773) 4243 (26.9%) View
BLUF (PF04940) 1906 (12.1%) View
DUF1115 (PF06544) 1841 (11.7%) View
Total: 4 Total: 15767 Clan alignment

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Family relationships

This diagram shows the relationships between members of this clan. More...

Species distribution

Tree controls


This tree shows the occurrence of the domains in this clan across different species. More...



There are 6 interactions for this clan. More...

Interacting families
Acylphosphatase Acylphosphatase


For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between the Pfam families in this clan, the corresponding UniProt entries, and the region of the three-dimensional structures that are available for that sequence.

Loading structure mapping...