Please note: this site relies heavily on the use of javascript. Without a javascript-enabled browser, this site will not function correctly. Please enable javascript and reload the page, or switch to a different browser.
210  structures 13208  species 24  interactions 130692  sequences 222  architectures

Clan: Adhesin (CL0204)

Summary

Bacterial adhesin superfamily Add an annotation

This superfamily includes a variety of bacterial adhesins that have a jelly-roll beta-barrel fold [1]. These domains are involved in sugar recognition.

This clan contains 10 families and the total number of domains in the clan is 130692. The clan was built by A Bateman.

Literature references

  1. Merckel MC, Tanskanen J, Edelman S, Westerlund-Wikstrom B, Korhonen TK, Goldman A; , J Mol Biol 2003;331:897-905.: The structural basis of receptor-binding by Escherichia coli associated with diarrhea and septicemia. PUBMED:12909017 EPMC:12909017

Members

This clan contains the following 10 member families:

Adhesin_Dr Collagen_bind DUF1120 DUF2807 DUF4097 FimA Fimbrial FimH_man-bind PapG_N SCPU

External database links

Domain organisation

Below is a listing of the unique domain organisations or architectures from this clan. More...

Loading domain graphics...

Alignments

The table below shows the number of occurrences of each domain throughout the sequence database. More...

Pfam family Num. domains Alignment
Fimbrial (PF00419) 94432 (72.3%) View
DUF4097 (PF13349) 10627 (8.1%) View
SCPU (PF05229) 7107 (5.4%) View
Collagen_bind (PF05737) 7005 (5.4%) View
FimH_man-bind (PF09160) 4193 (3.2%) View
FimA (PF16970) 3104 (2.4%) View
DUF2807 (PF10988) 1939 (1.5%) View
DUF1120 (PF06551) 1756 (1.3%) View
PapG_N (PF03627) 416 (0.3%) View
Adhesin_Dr (PF04619) 113 (0.1%) View
Total: 10 Total: 130692 Clan alignment
 

Please note: Clan alignments can be very large and can cause problems for some browsers. Read the note above before viewing.

Family relationships

This diagram shows the relationships between members of this clan. More...

Species distribution

Tree controls

Hide

This tree shows the occurrence of the domains in this clan across different species. More...

Loading...

Interactions

There are 24 interactions for this clan. More...

Interacting families
A B
Adhesin_Dr Adhesin_Dr
Collagen_bind Collagen
Collagen_bind
DUF2807 DUF2807
Fim-adh_lectin Fimbrial
Fimbrial Fimbrial
FimH_man-bind
PapC_N
PapD_C
PapD_N
Usher
FimH_man-bind Fimbrial
FimH_man-bind
PapC_N
PapD_C
Usher
PapC_N Fimbrial
PapD_C Fimbrial
FimH_man-bind
PapG_N
PapD_N Fimbrial
FimH_man-bind
PapG_N
PapG_N PapG_C

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between the Pfam families in this clan, the corresponding UniProt entries, and the region of the three-dimensional structures that are available for that sequence.

Loading structure mapping...