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3098  structures 7067  species 78  interactions 153254  sequences 9759  architectures

Clan: Concanavalin (CL0004)

Summary

Concanavalin-like lectin/glucanase superfamily Add an annotation

This superfamily includes a diverse range of carbohydrate binding domains and glycosyl hydrolase enzymes that share a common structure.

This clan contains 49 families and the total number of domains in the clan is 153254. The clan was built by A Bateman.

Members

This clan contains the following 49 member families:

Alginate_lyase2 ArabFuran-catal Arabino_trans_N Bac_rhamnosid Bact_lectin Calreticulin Cleaved_Adhesin DUF1080 DUF1349 DUF1583 DUF1961 DUF2401 DUF3472 DUF4975 Exotox-A_bind Gal-bind_lectin GalBD_like GH131_N GH43_C2 Glyco_hydro_11 Glyco_hydro_12 Glyco_hydro_16 Glyco_hydro_32C Glyco_hydro_7 HA1 Laminin_G_1 Laminin_G_2 Laminin_G_3 Lectin_leg-like Lectin_legB MAM Methyltransf_FA Neuralized Pentaxin Peptidase_A4 Polysacc_lyase PRY Reoviridae_Vp9 Sial-lect-inser Sialidase SKN1 Spike_NTD SPRY TgMIC1 Toxin_R_bind_N TSP_C VP4_haemagglut XET_C YrpD

External database links

Domain organisation

Below is a listing of the unique domain organisations or architectures from this clan. More...

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Alignments

The table below shows the number of occurrences of each domain throughout the sequence database. More...

Pfam family Num. domains Alignment
Laminin_G_2 (PF02210) 20155 (13.2%) View
SPRY (PF00622) 18768 (12.2%) View
Laminin_G_3 (PF13385) 17590 (11.5%) View
Glyco_hydro_16 (PF00722) 14911 (9.7%) View
MAM (PF00629) 7975 (5.2%) View
PRY (PF13765) 7262 (4.7%) View
DUF1080 (PF06439) 6164 (4.0%) View
Glyco_hydro_32C (PF08244) 5648 (3.7%) View
Gal-bind_lectin (PF00337) 5599 (3.7%) View
GH43_C2 (PF17851) 4950 (3.2%) View
Lectin_legB (PF00139) 4748 (3.1%) View
Laminin_G_1 (PF00054) 4713 (3.1%) View
Calreticulin (PF00262) 3639 (2.4%) View
Bac_rhamnosid (PF05592) 3015 (2.0%) View
XET_C (PF06955) 2907 (1.9%) View
Neuralized (PF07177) 2667 (1.7%) View
Lectin_leg-like (PF03388) 2264 (1.5%) View
DUF1349 (PF07081) 2034 (1.3%) View
Pentaxin (PF00354) 2021 (1.3%) View
SKN1 (PF03935) 1977 (1.3%) View
Glyco_hydro_11 (PF00457) 1575 (1.0%) View
Glyco_hydro_12 (PF01670) 1571 (1.0%) View
Glyco_hydro_7 (PF00840) 1407 (0.9%) View
Alginate_lyase2 (PF08787) 1129 (0.7%) View
Peptidase_A4 (PF01828) 1035 (0.7%) View
continued
Pfam family Num. domains Alignment
TSP_C (PF05735) 944 (0.6%) View
Methyltransf_FA (PF12248) 898 (0.6%) View
Polysacc_lyase (PF14099) 793 (0.5%) View
Arabino_trans_N (PF17689) 757 (0.5%) View
GH131_N (PF18271) 756 (0.5%) View
Bact_lectin (PF18483) 688 (0.4%) View
ArabFuran-catal (PF09206) 639 (0.4%) View
DUF2401 (PF10287) 453 (0.3%) View
Cleaved_Adhesin (PF07675) 432 (0.3%) View
DUF3472 (PF11958) 401 (0.3%) View
GalBD_like (PF17974) 217 (0.1%) View
DUF1961 (PF09224) 178 (0.1%) View
DUF4975 (PF16346) 148 (0.1%) View
Sialidase (PF02973) 64 (0.0%) View
DUF1583 (PF07622) 54 (0.0%) View
YrpD (PF15493) 23 (0.0%) View
Toxin_R_bind_N (PF07953) 20 (0.0%) View
Sial-lect-inser (PF09264) 17 (0.0%) View
Spike_NTD (PF16451) 16 (0.0%) View
VP4_haemagglut (PF00426) 10 (0.0%) View
Exotox-A_bind (PF09101) 7 (0.0%) View
HA1 (PF18239) 6 (0.0%) View
TgMIC1 (PF11476) 5 (0.0%) View
Reoviridae_Vp9 (PF08978) 4 (0.0%) View
Total: 49 Total: 153254
No alignment ℹ
 

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Family relationships

This diagram shows the relationships between members of this clan. More...

Species distribution

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This tree shows the occurrence of the domains in this clan across different species. More...

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Interactions

There are 78 interactions for this clan. More...

Interacting families
A B
Alginate_lyase2 Alginate_lyase2
Alpha-amylase Lectin_legB
ArabFuran-catal AbfB
Astacin MAM
Atg8 Calreticulin
Bac_rhamnosid Bac_rhamnosid
Bac_rhamnosid_N
Bac_rhamnosid_N Bac_rhamnosid
BNR_3 Laminin_G_3
C1-set PRY
SPRY
Calreticulin Calreticulin
CBM_6 Glyco_hydro_11
Cleaved_Adhesin Cleaved_Adhesin
COesterase Laminin_G_2
DUF1080 DUF1080
DUF1349 DUF1349
DUF1961 DUF1961
DUF3357 Glyco_hydro_32C
EGF_3 TSP_C
EGF_CA Laminin_G_2
Exotox-A_bind Exotox-A_cataly
Exotox-A_target
F5_F8_type_C Sialidase
Gal-bind_lectin Gal-bind_lectin
Glyco_hydro_11 CBM_6
Glyco_hydro_11
TAXi_C
Glyco_hydro_12 Glyco_hydro_12
Glyco_hydro_16 Glyco_hydro_16
XET_C
Glyco_hydro_18 Glyco_hydro_11
Glyco_hydro_32C Glyco_hydro_32C
Glyco_hydro_32N
PMEI
Glyco_hydro_32N Glyco_hydro_32C
Glyco_hydro_7 Glyco_hydro_7
Laminin_G_1 Ig_2
Laminin_G_1
Laminin_G_2
Ldl_recept_b
V-set
Laminin_G_2 Laminin_G_2
Laminin_II Laminin_G_1
Ldl_recept_b Laminin_G_1
Lectin_leg-like EF-hand_7
Lectin_leg-like
Lectin_legB Lectin_legB
Transferrin
MAM ig
MATH
Pentaxin Ig_2
Pentaxin
Peptidase_A4 Peptidase_A4
Peptidase_M27 Toxin_R_bind_N
PRY PRY
SPRY
RDM PRY
SPRY
Reoviridae_Vp9 Reoviridae_Vp9
Sial-lect-inser BNR_2
Sial-lect-inser
Sialidase BNR_2
SPRY PRY
SPRY
TAXi_C Glyco_hydro_11
Glyco_hydro_12
TAXi_N Glyco_hydro_11
Toxin_R_bind_C Toxin_R_bind_N
Toxin_R_bind_N NTNH_C
Toxin_R_bind_C
Toxin_R_bind_N
Toxin_trans Toxin_R_bind_N
TSP_3 TSP_C
VP4_haemagglut VP4_haemagglut
VP7 VP4_haemagglut
XET_C Glyco_hydro_16
XET_C

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between the Pfam families in this clan, the corresponding UniProt entries, and the region of the three-dimensional structures that are available for that sequence.

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