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1631  structures 3131  species 15  interactions 34755  sequences 2750  architectures

Clan: Concanavalin (CL0004)


Concanavalin-like lectin/glucanase superfamily Add an annotation

This superfamily includes a diverse range of carbohydrate binding domains and glycosyl hydrolase enzymes that share a common structure.

This clan contains 16 families and the total number of domains in the clan is 34755. The clan was built by A Bateman.


This clan contains the following 16 member families:

DUF1080 DUF2401 Gal-bind_lectin Glyco_hydro_11 Glyco_hydro_12 Glyco_hydro_16 Glyco_hydro_7 Laminin_G_1 Laminin_G_2 Laminin_G_3 Lectin_leg-like Lectin_legB Pentaxin Sialidase SKN1 Toxin_R_bind_N

External database links

Domain organisation

Below is a listing of the unique domain organisations or architectures from this clan. More...

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The table below shows the number of occurrences of each domain throughout the sequence database. More...

Pfam family Num. domains Alignment
Laminin_G_2 (PF02210) 7915 (22.8%) View
Laminin_G_3 (PF13385) 6160 (17.7%) View
Glyco_hydro_7 (PF00840) 5196 (15.0%) View
Glyco_hydro_16 (PF00722) 4255 (12.2%) View
Gal-bind_lectin (PF00337) 2093 (6.0%) View
Lectin_legB (PF00139) 1651 (4.8%) View
Laminin_G_1 (PF00054) 1504 (4.3%) View
DUF1080 (PF06439) 1312 (3.8%) View
Pentaxin (PF00354) 1094 (3.1%) View
Glyco_hydro_11 (PF00457) 815 (2.3%) View
Lectin_leg-like (PF03388) 783 (2.3%) View
Sialidase (PF02973) 557 (1.6%) View
Glyco_hydro_12 (PF01670) 532 (1.5%) View
SKN1 (PF03935) 512 (1.5%) View
Toxin_R_bind_N (PF07953) 203 (0.6%) View
DUF2401 (PF10287) 173 (0.5%) View
Total: 16 Total: 34755 Clan alignment

Please note: Clan alignments can be very large and can cause problems for some browsers. Read the note above before viewing.

Family relationships

This diagram shows the relationships between members of this clan. More...

Species distribution

Tree controls


This tree shows the occurrence of the domains in this clan across different species. More...



There are 15 interactions for this clan. More...

Interacting families
Lectin_legB Lectin_legB
Laminin_G_2 Laminin_G_2
Lectin_leg-like Lectin_leg-like
Laminin_G_1 Laminin_G_1
Gal-bind_lectin Gal-bind_lectin
Glyco_hydro_11 Glyco_hydro_11
Toxin_R_bind_N Toxin_R_bind_C
Glyco_hydro_16 Glyco_hydro_16
Pentaxin Pentaxin
Glyco_hydro_12 Glyco_hydro_12


For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between the Pfam families in this clan, the corresponding UniProt entries, and the region of the three-dimensional structures that are available for that sequence.

Loading structure mapping...