Please note: this site relies heavily on the use of javascript. Without a javascript-enabled browser, this site will not function correctly. Please enable javascript and reload the page, or switch to a different browser.
4282  structures 6880  species 0  interactions 259538  sequences 14002  architectures

Clan: Concanavalin (CL0004)


Concanavalin-like lectin/glucanase superfamily Add an annotation

This superfamily includes a diverse range of carbohydrate binding domains and glycosyl hydrolase enzymes that share a common structure.

This clan contains 50 families and the total number of domains in the clan is 259538. The clan was built by A Bateman.


This clan contains the following 50 member families:

Alginate_lyase2 ArabFuran-catal Arabino_trans_N Bac_rhamnosid Bact_lectin bCoV_S1_N Calreticulin Cleaved_Adhesin DUF1080 DUF1349 DUF1583 DUF1961 DUF2401 DUF3472 DUF4975 DUF6250 Exotox-A_bind Gal-bind_lectin GalBD_like GH131_N GH43_C2 Glyco_hydro_11 Glyco_hydro_12 Glyco_hydro_16 Glyco_hydro_32C Glyco_hydro_7 HA1 Laminin_G_1 Laminin_G_2 Laminin_G_3 Lectin_leg-like Lectin_legB MAM Methyltransf_FA Neuralized Pentaxin Peptidase_A4 Polysacc_lyase PRY Reoviridae_Vp9 Sial-lect-inser Sialidase SKN1_KRE6_Sbg1 SPRY TgMIC1 Toxin_R_bind_N TSP_C VP4_haemagglut XET_C YrpD

External database links

Domain organisation

Below is a listing of the unique domain organisations or architectures from this clan. More...

Loading domain graphics...


The table below shows the number of occurrences of each domain throughout the sequence database. More...

Pfam family Num. domains Alignment
Laminin_G_2 (PF02210) 43213 (16.6%) View
SPRY (PF00622) 37345 (14.4%) View
Laminin_G_3 (PF13385) 21769 (8.4%) View
Glyco_hydro_16 (PF00722) 21084 (8.1%) View
PRY (PF13765) 18699 (7.2%) View
MAM (PF00629) 15824 (6.1%) View
Laminin_G_1 (PF00054) 9523 (3.7%) View
DUF1080 (PF06439) 8576 (3.3%) View
Gal-bind_lectin (PF00337) 8550 (3.3%) View
Lectin_legB (PF00139) 8429 (3.2%) View
Glyco_hydro_32C (PF08244) 7464 (2.9%) View
Calreticulin (PF00262) 6113 (2.4%) View
GH43_C2 (PF17851) 5876 (2.3%) View
XET_C (PF06955) 5101 (2.0%) View
Neuralized (PF07177) 4904 (1.9%) View
Pentaxin (PF00354) 4224 (1.6%) View
Bac_rhamnosid (PF05592) 4100 (1.6%) View
Lectin_leg-like (PF03388) 3349 (1.3%) View
SKN1_KRE6_Sbg1 (PF03935) 2948 (1.1%) View
TSP_C (PF05735) 2687 (1.0%) View
DUF1349 (PF07081) 2367 (0.9%) View
Glyco_hydro_12 (PF01670) 2223 (0.9%) View
Glyco_hydro_11 (PF00457) 2046 (0.8%) View
Glyco_hydro_7 (PF00840) 2024 (0.8%) View
Alginate_lyase2 (PF08787) 1567 (0.6%) View
Peptidase_A4 (PF01828) 1509 (0.6%) View
Pfam family Num. domains Alignment
GH131_N (PF18271) 1091 (0.4%) View
Methyltransf_FA (PF12248) 1027 (0.4%) View
Polysacc_lyase (PF14099) 902 (0.3%) View
ArabFuran-catal (PF09206) 869 (0.3%) View
Arabino_trans_N (PF17689) 664 (0.3%) View
Cleaved_Adhesin (PF07675) 619 (0.2%) View
Bact_lectin (PF18483) 613 (0.2%) View
DUF2401 (PF10287) 611 (0.2%) View
DUF3472 (PF11958) 490 (0.2%) View
GalBD_like (PF17974) 289 (0.1%) View
DUF6250 (PF19763) 245 (0.1%) View
DUF1961 (PF09224) 224 (0.1%) View
DUF1583 (PF07622) 97 (0.0%) View
DUF4975 (PF16346) 88 (0.0%) View
Sialidase (PF02973) 73 (0.0%) View
bCoV_S1_N (PF16451) 47 (0.0%) View
YrpD (PF15493) 16 (0.0%) View
Toxin_R_bind_N (PF07953) 16 (0.0%) View
Sial-lect-inser (PF09264) 15 (0.0%) View
HA1 (PF18239) 7 (0.0%) View
VP4_haemagglut (PF00426) 7 (0.0%) View
Exotox-A_bind (PF09101) 6 (0.0%) View
Reoviridae_Vp9 (PF08978) 4 (0.0%) View
TgMIC1 (PF11476) 4 (0.0%) View
Total: 50 Total: 259538
No alignment ℹ

Please note: Clan alignments can be very large and can cause problems for some browsers. Read the note above before viewing.

Family relationships

This diagram shows the relationships between members of this clan. More...

Species distribution

Tree controls


This tree shows the occurrence of the domains in this clan across different species. More...



For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between the Pfam families in this clan, the corresponding UniProt entries, and the region of the three-dimensional structures that are available for that sequence.

Loading structure mapping...