Please note: this site relies heavily on the use of javascript. Without a javascript-enabled browser, this site will not function correctly. Please enable javascript and reload the page, or switch to a different browser.
182  structures 10123  species 13  interactions 16695  sequences 64  architectures

Clan: Rubredoxin (CL0045)

Summary

Rubredoxin-like Add an annotation

The Rubredoxin clan is comprised of three families:Rubredoxin, COX5B and desulforedoxin.Rubredoxin domains are small domains (5-6 kDa) and bind one iron atom tetrahedrally bound by four cysteine residues.Similar, desulforedoxin domains are small (4 kDa), but usually form homodimers. Each monomer binds one iron atom, but in a distorted tetrahedral arrangement. COX5B domains are membrane-anchored rubredoxin-like domains. The domain in the Rubredoxin clan are usually comprised of 2 alpha helixes and 2-3 beta strands.

This clan contains 4 families and the total number of domains in the clan is 16695. The clan was built by RD Finn.

Members

This clan contains the following 4 member families:

COX5B Desulfoferrod_N Rubredoxin zf-CHCC

External database links

Domain organisation

Below is a listing of the unique domain organisations or architectures from this clan. More...

Loading domain graphics...

Alignments

The table below shows the number of occurrences of each domain throughout the sequence database. More...

Pfam family Num. domains Alignment
Rubredoxin (PF00301) 12930 (77.4%) View
zf-CHCC (PF10276) 2041 (12.2%) View
Desulfoferrod_N (PF06397) 966 (5.8%) View
COX5B (PF01215) 758 (4.5%) View
Total: 4 Total: 16695 Clan alignment
 

Please note: Clan alignments can be very large and can cause problems for some browsers. Read the note above before viewing.

Family relationships

This diagram shows the relationships between members of this clan. More...

Species distribution

Tree controls

Hide

This tree shows the occurrence of the domains in this clan across different species. More...

Loading...

Interactions

There are 13 interactions for this clan. More...

Interacting families
A B
COX1 COX5B
COX3 COX5B
COX4 COX5B
COX5A COX5B
COX5B COX5A
COX5B
COX6A
COX7a
COX6A COX5B
Desulfoferrod_N Desulfoferrod_N
Desulfoferrodox
Desulfoferrodox Desulfoferrod_N
Rubredoxin Rubredoxin

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between the Pfam families in this clan, the corresponding UniProt entries, and the region of the three-dimensional structures that are available for that sequence.

Loading structure mapping...