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810  structures 1605  species 30  interactions 22227  sequences 1076  architectures

Clan: C_Lectin (CL0056)

Summary

C-type lectin-like superfamily Add an annotation

This clan contains domains that have a C-type lectin fold. Many of these are known or expected to mediate interactions with sugars.

This clan contains 7 families and the total number of domains in the clan is 22227. The clan was built by A Bateman.

Members

This clan contains the following 7 member families:

APT C4 Chordopox_A33R Herpes_UL45 Intimin_C Lectin_C Xlink

External database links

Domain organisation

Below is a listing of the unique domain organisations or architectures from this clan. More...

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Alignments

The table below shows the number of occurrences of each domain throughout the sequence database. More...

Pfam family Num. domains Alignment
Lectin_C (PF00059) 17045 (76.7%) View
Xlink (PF00193) 2130 (9.6%) View
C4 (PF01413) 1621 (7.3%) View
Intimin_C (PF07979) 991 (4.5%) View
APT (PF03440) 249 (1.1%) View
Herpes_UL45 (PF05473) 118 (0.5%) View
Chordopox_A33R (PF05966) 73 (0.3%) View
Total: 7 Total: 22227 Clan alignment
 

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Family relationships

This diagram shows the relationships between members of this clan. More...

Species distribution

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This tree shows the occurrence of the domains in this clan across different species. More...

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Interactions

There are 30 interactions for this clan. More...

Interacting families
A B
ADAM_CR Lectin_C
Aerolysin APT
APT Aerolysin
APT
Pertus-S4-tox
Pertussis_S2S3
Big_2 Intimin_C
C1-set Lectin_C
C4 C4
Cadherin Lectin_C
Chordopox_A33R Chordopox_A33R
fn3 Lectin_C
Intimin_C Big_2
Intimin_C
Tir_receptor_M
Lectin_C C1-set
EGF
Gla
Lectin_C
Ly49
MHC_I
Surfac_D-trimer
VWA
Ly49 Lectin_C
MHC_I Lectin_C
MHC_II_beta Lectin_C
Pertus-S4-tox APT
Surfac_D-trimer Lectin_C
VWA Lectin_C
Xlink Xlink

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between the Pfam families in this clan, the corresponding UniProt entries, and the region of the three-dimensional structures that are available for that sequence.

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