Sequence alignment for CL0068

PF05186

Q9W1Z4_DROME/286-327EQGKYLADSLADPLIKALTEIANKRPRDPVAYLTNYL----QHFMG
Q9VKQ9_DROME/77-118PTRQYLDQTVAPVLLHGMQALARERPTDPIQFLASYL----LKHSN
O97242_PLAF7/1042-1083PLRFYLIKNILPILTDALIYICKTKPKNPCLHIAQYL----LENAH
Q9VZJ1_DROME/47-88PVRQYLDQTVAPILLHGLQALARDRPSDPISYLATYL----LKNKN
DPY30_HUMAN/52-93PTRAYLDQTVVPILLQGLAVLAKERPPNPIEFLASYL----LKNKA
SDC1_SCHPO/6-47PARQYLNEKVTPVLLEGMKILARDRPENPLQFLGQFL----LDANA
KAD7_MOUSE/570-611PLRNYLMTYVMPTLMQGLNECCKVRPEDPVDFLAEYL----FKNNP
DPY30_CAEEL/69-110PTRQYLDSTVVPILLQGLGALAKDRPENPIEFLANFL----LREKD
NDK5_HUMAN/156-197AAKDYLNLHIMPTLLEGLTELCKQKPADPLIWLADWL----LKNNP
Q21753_CAEEL/147-188HAKDYLSVEVWPKLSQGLARVAVERPDNPIKWLADYL----HQLRQ
DYDC1_MOUSE/1-42MESRYLQKCLGTCLTQGLTEVARVRPLDPIEYLAFWL----YKHKE
NDK5_MOUSE/156-197AAKDYINLYVAPTLLQGLTELCKEKPPDPYLWLADWL----MKNNP
Q9D3X8_MOUSE/1-42MDTAYLKNCFGTGLTQALAEVARVRPSDPIEYLAHWL----YHYRS
SDC1_YEAST/121-162QTRKYLNTNVTPHLLAGMRLIAVQQPEDPLRVLGEYL----IEQSN

PF02197

Q15300_HUMAN/25-62-------HNIQALLKDSIVQLCTARPERPMAFLREYF.ERLEKEEA
KAP3_RAT/7-44-------AGLTELLQGFTVEVLRHQPADLLEFALQHF.TRLQQENE
KAP2_HUMAN/8-45-------PGLTELLQGYTVEVLRQQPPDLVEFAVEYF.TRLREARA
KAPR_YEAST/7-45-------KESQAELQLFQNEINAANPSDFLQFSANYFNKRLEQQRA
KAPR_CAEEL/20-57-------HNIQQLVKEAIVVLCIHKPDNPVLFLKDHF.EKLNEQRA
KAPR_BLAEM/8-45-------SELPPILKDLSREVLRHQPADLVQFCHDYF.AKLLAQQR
SP17_PAPHA/14-51-------QGFGNLLEGLTREILREQPDNIPAFAAAYF.ESLLEKRE
KAPR_STRPU/7-44-------EGLTDLLQDFTVAVLREKPSDLVEFASSYF.AKLQENNI
Q20199_CAEEL/11-48-------HDLRPILEALAREVLRSQPSDVAEFGHMFF.DEYLKHRR
KAPR_USTMA/5-43-------SSYTALLNDLNRDVARARPADALQFCANWFNSKLEEQRR
CABYR_HUMAN/12-49-------YGLKTLLEGISRAVLKTNPSNINQFAAAYF.QELTMYRG
KAPR_SCHPO/1-39-------MSFEEVYEELKALVDEQNPSDVLQFCYDFFGEKLKAERS
KAPR1_DROME/24-61-------HGIQRVLKDCIVQLCVCRPENPVQFLRQYF.QKLEREQV

This alignment is coloured according to the ClustalX colouring scheme:

 
Glycine (G)
 
Proline (P)
 
Small or hydrophobic (C,A,V,L,I,M,F,W)
 
Hydroxyl or amine amino acids (S,T,N,Q)
 
Charged amino-acids (D,E,R,K)
 
Histidine or tyrosine (H,Y)

For UniProt-based alignments, we also add some additional mark-up to the alignments where appropriate. Active site information is shown as follows:

 
Active site (residue annotated in SwissProt as an active site)
 
Predicted active site (residue aligns in a Pfam alignment with a SwissProt active site)
 
Predicted active site (residue annotated in SwissProt as a potential active site)

Some UniProt sequences can be mapped to protein structures, in which case we also show the secondary structure definition. These lines are shown below the sequence to which they apply and are marked (SS). The meaning of each of the symbols is as follows:

C
Random coil
H
Alpha-helix
G
3(10) helix
I
Pi-helix
E
Hydrogen bonded beta-strand (extended strand)
B
Residue in isolated beta-bridge
T
H-bonded turn (3-turn, 4-turn, or 5-turn)
S
Bend (five-residue bend centered at residue i)
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