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31  structures 10050  species 4  interactions 33815  sequences 257  architectures

Clan: MBD-like (CL0081)

Summary

MBD-like DNA-binding domain Add an annotation

This clan contains proteins with a distinctive three stranded DNA-binding domain [1].

This clan contains 7 families and the total number of domains in the clan is 33815. The clan was built by A Bateman.

Literature references

  1. Connolly KM, Ilangovan U, Wojciak JM, Iwahara M, Clubb RT; , J Mol Biol 2000;300:841-856.: Major groove recognition by three-stranded beta-sheets: affinity determinants and conserved structural features. PUBMED:10891272 EPMC:10891272

Members

This clan contains the following 7 member families:

AP2 DUF3596 Integrase_AP2 Integrase_DNA MBD MBDa Phage_integ_N

External database links

Domain organisation

Below is a listing of the unique domain organisations or architectures from this clan. More...

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Alignments

The table below shows the number of occurrences of each domain throughout the sequence database. More...

Pfam family Num. domains Alignment
AP2 (PF00847) 11961 (35.4%) View
Integrase_AP2 (PF14657) 9598 (28.4%) View
Phage_integ_N (PF09003) 4374 (12.9%) View
DUF3596 (PF12167) 3716 (11.0%) View
Integrase_DNA (PF02920) 2052 (6.1%) View
MBD (PF01429) 1791 (5.3%) View
MBDa (PF16564) 323 (1.0%) View
Total: 7 Total: 33815 Clan alignment
 

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Family relationships

This diagram shows the relationships between members of this clan. More...

Species distribution

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This tree shows the occurrence of the domains in this clan across different species. More...

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Interactions

There are 4 interactions for this clan. More...

Interacting families
A B
AP2 AP2
Phage_int_SAM_1 Phage_integ_N
Phage_integ_N Phage_int_SAM_1
Phage_integ_N

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between the Pfam families in this clan, the corresponding UniProt entries, and the region of the three-dimensional structures that are available for that sequence.

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