Sequence alignment for CL0099

PF05893

Q8G6W7_BIFLO/65-480------------------LAAMS-----VNDILDIVA-DAAQL---------------------------W-ADPDFEL-
Q7MZU4_PHOLL/30-413------------------ACPPS-----VQQVLACAE-RFVDD---------------------------L-DNV....-
Q7NQ23_CHRVO/30-413------------------AAEPD-----VDAVLSCAE-RFADA---------------------------L-AGA....-
Q3KD56_PSEPF/30-413------------------ARALD-----TTTVLGAAA-IFAER---------------------------L-QDP....-
Q93CP6_PHOLU/52-446------------------NNKLR-----LHNIVNFLY-TVGQR---------------------------W-KNEEYSR-
LUXC2_PHOLE/50-444------------------ENKLT-----INQIVNFLY-TVGQK---------------------------W-KSETYSR-
LUXC_VIBFI/51-445------------------RINLN-----LNQIVNFLY-TVGQR---------------------------W-KSEEYNR-
Q4A539_9GAMM/49-442------------------VNNLR-----LNQVVNFLY-TVGQR---------------------------W-RSEEYTR-
LUXC_VIBHA/49-443------------------LNDLN-----INNIINFLY-TTGQR---------------------------W-KSEEYSR-
A8LEK2_FRASN/68-470------------------LLNVP-----LKEIIDFLV-ETGER---------------------------I-RDPRNTF-
Q97GS8_CLOAB/45-446------------------VHDIK-----TEETIDLLD-RCAKL---------------------------W-LDDNYSK-
A6LV85_CLOB8/35-425------------------IYSYP-----SEAMIEIIN-EYSKI---------------------------L-CSD....-
Q9KV99_VIBCH/423-818------------------LANQP-----LEAILGLIN-EARKS---------------------------W-SST....-

PF00171

Q7CTQ3_AGRT5/29-491FRPAGS......GKT.FKTINPA.....TGETLADIS.ACDVS.DVDYAVGKARA.AFDD.....GR...W.RLLPPGE-
Q7CSM1_AGRT5/15-474WRDAVS......GKT.IAVSDPA.....TDEIIGAIA.HAEKE.DLDLALAAAER.GFK.......L...W.RDTSPYE-
Q7D3N3_AGRT5/14-476FVSSS........KR.GRSIDPA.....TYETIGDYP.DDGGA.AAQSAIEAAKR.AFRG.....TA...W.RD.DAEL-
Q7CVT1_AGRT5/28-485WVERDQ........M.FAIVDPA.....GGDHLADVA.SCTLN.DVDFAIDAASK.AFA.......G...W.RDMLPVD-
A9A1B_DANRE/49-507KTKSEP............VFEPA....T.GRVLCRLQ.TCGSA.EVDAAVRNASA.AFK.......V...W.RKLSGME-
BETB_ECOLI/15-479YTSATS......GRT.FETINPA.....NGNVLATVQ.AAGRE.DVDRAVKSAQQ.GQK.......I...W.ASMTAME-
ALDA_ECOLI/18-475W...RG.......DAWIDVVNPA.....TEAVISRIP.DGQAE.DARKAIDAAER.AQP.......E...W.EALPAIE-
ASTD_PSEAE/10-467WLAGQG.......ET.LESLDPV.....GQGVVWSGR.GADAT.QVDAAVCAARE.AFP.......A...W.ARRPLEQ-
ALDH6_YEAST/34-496FMKAQD......GKT.YPVEDPS.....TENTVCEVS.SATTE.DVEYAIECADR.AFHD.....TE...W.ATQDPRE-
CROM_ENTDO/24-487FVDSVN......GKA.YSVINPC.....TTKKICDVQ.EGSKA.DIDKAVQACKL.AFKR.....GT..PW.RRMDASR-
O66573_AQUAE/12-471WVDKE.........EKIEVIYPY.....TRKPIGRVP.KGDEK.DVEKAIERAKE.GFK.......E...I.FSLTAYE-
Q6BX25_DEBHA/48-514WVASSD......NST.FEVNNPALA.SGAGTKIADVS.SMTTK.DYVRAINSAQD.AFS.......D...F.KKTTGRY-
Q93HF8_STRAW/48-523FTSVSL.......KR.SLEQDPESEAAQHPYVVGRCA.VADDS.AIDMATQAAAAAASD...........W.AAVPLER-
LADH_METJA/7-459WIN..........REDMDVINPY.....SLEVIKKIP.ALSRE.EAKEAIDTAEK.YKE.......V...M.KNLPITK-
Q739I7_BACC1/23-485YVDSVC......GET.FDTFNPA.....TNRKLASIA.KANEE.DTKRAIDVAER.TFKS.....GI...W.SKMPVEE-
O33455_PSEPU/24-488WKGSIS......GET.ITVENPA.....TEEIIAHIP.QGRHE.DIDEAVRVARA.TFES.....PA...W.RKIRPID-
O86742_STRCO/16-473FRDAAD......GRT.TEVVNPA.....TGEAYATAP.LSGQA.DVDAAMAAAAA.AFP.......A...W.RDLVPAE-
Q7W0D6_BORPE/10-472WL..DG......VDA.RPNINPS....NLADVVGDYA.QADAA.QAGMAIAAASA.AAH.......A...W.ARSTGQR-
O52642_9PSED/19-476WVEAQG......G.V.ANVVDPS.....NGNIIGVTG.VANGK.DVDAAVNAAKR.AQK.......E...W.AAIPFSE-
Q7UJE5_RHOBA/56-500IVLNNA...............PQ...............VATSE.NANSNRPGAERIGYH.......GGSNW.ATWSIRK-
Q98LH9_RHILO/20-482FVDGSG.......SGSIERRSPA.....TGDLVARYA.DGTPE.DVDLAVEAARI.AFED.....GP...W.PRMSGME-
Q6ABP5_PROAC/22-479WVDAEA.......SRTFDVINPA.....TEKPLVAIA.DASVD.QGTDALDAAVR.AQH.......S...W.ADTAPRE-
Q6ALY1_DESPS/13-480WRRSKT.......TSYADLYNPS.....TGEVTAQVA.HCTAE.EVEEAIASAAA.AYP.......G...W.AATPVGK-
Q82GU8_STRAW/29-495WVAPDG.......GH.YEVIDPA.....TEAVVGWAP.EASRD.QVHAAAAAARE.AFA.......A...W.SRTPAEE-
Q6N3D4_RHOPA/38-498IVAASS......GEV.FETASPI.....DNSVLAQVA.RGTAA.DIDRAAKAAKA.AFP.......A...W.RDMAPAK-
ALDA_STAAS/21-483FVKGSS.......DETIEVTNPA.....TGETLSHIT.RAKDK.DVDHAVKVAQD.AFE.......S...W.SLTSKSE-
Q8A340_BACTN/495-936YTDRCQ.....................DDEVCICEMS.QADSA.QVEKIIEIAEADPAG...........W.RKTTLEE-
Q6PW33_9RALS/11-473FVAALS......GET.LATLNPH.....DNSEIAQVS.MAGRE.DVDRAVQAAKK.AFP.......A...W.SAMAAAD-
BETB_BACSU/11-476WISAEK.......EQIRSIINPF.....NQEEIATVS.EGGRE.DAIKAIAAARR.AFDK.....GE...W.SSLSGLE-
P74275_SYNY3/509-973YV..ET......ANY.IDSVNPC....RPSQAIGKVG.LISVE.QADHALEIAKA.AFP.......A...W.KKTPVRE-
O06837_PSEFL/29-498WVNAQS......DKT.LNVYNPA.....TGDTLTDVP.DGDVE.DVNAAVESAAA.TLQS.....DA...W.RRMPPSA-
Q8GPZ0_PSEAI/20-479IRKETN.......VTAFNVFSPI.....DGRKLLVGN.TSSDA.EVAAALNAAET.AFK.......T...W.KLSSKLE-
Q7WPE0_BORBR/13-475FHPCGG.......AAVLPVYNPA.....TEQAEASVR.ACSAD.DLERAVRAAAA.AGP.......G...W.GAAPPAQ-
Q6AA40_PROAC/499-947WAGEVA........EKMKGCELG......ESTLANNH.LDTIA.EVNAVIATALE.AQH.......S...W.AGRGGNA-
P96405_MYCTU/17-478WTKPST......SDV.IEVRCPA.....TGEYVGKVP.MAAAA.DVDAAVAAARA.AFDN.....GP...W.PSTPPHE-
Q8ELI8_OCEIH/14-471WLTTD........REKQEIKNPF.....TGEVIGEQY.FAQSD.DVEIALATAYK.GKK.......Q...V.KNIPIIE-
Q9RZE6_DEIRA/24-482WRNA.........PRNFEVRHPG.....NGEVIGEVA.DCTPT.DARQAIDAAEV.ALR.......E...W.RQVNPYE-
AL1L1_HUMAN/430-898FVDAEG......AKT.SETINPT.....DGSVICQVS.LAQVT.DVDKAVAAAKD.AFEN.....GR...W.GKISARD-
ALDH5_BACSU/16-474WQEGSS......PNV.LENKNPY.....TQKTFTTFR.KATAD.DVDEAYRAAAL.AKK.......K...W.DAVNPFE-
Q97UA1_SULSO/11-474WIK.GS......GEE.YLDINPA....DKDHVLAKIR.LYTKD.DVKEAINKAVA.KFD.......E...W.SRTPAPK-
Q92XQ0_RHIME/15-479WVAPAS......GEY.IETVDPF.....TARPWALVP.RGNAE.DADRAVRAAHR.AFSQ.....GP...W.GKMHPTE-
O24897_HELPY/516-965FEDPNL........TPLEVFDRI.....HHKKIASVH.LADKE.AILKALEVAKSDKSR...........F.SQKSFTE-
Q18822_CAEEL/36-498FARS.........EKLMDSVNPS.....TGKPWIKIP.DGTAR.EVDQAVEAAKE.AFK.......T...W.KKTTVQQ-
O49218_ORYSA/49-511FVESRA.......DEHVDVTNPA.....TQEVVSRIP.LTTAD.EFRAAVDAART.AFP.......G...W.RNTPVTT-
Q8KVX3_9RHOB/30-494WVDSED.......GTTFDTINPA.....TGETIAKVA.SGKAA.DIDKAVKNARE.TFKS.....GV...W.SMLAPRE-
Q20352_CAEEL/214-676HVEFPS.......DRKFEVIEPR.....SGKPMATWH.YATRD.QVDLTVKEAKK.AQK.......Q...W.AKSSWME-
Q88PZ0_PSEPK/11-471WVEGQG......SDC.ISVNDPA.....LGQPFAELM.AASVS.QVDQAVAAARS.ALP......A....W.KSTCASE-
Q881E4_PSESM/24-482WIPSSS......A.L.LPVIEPA.....TSELLMNTA.MAGAA.DIAIACREAAL.AQP.......A...W.AAMGPRE-
Q6HJ76_BACHK/11-470WKSVNT......YKP...LYAPY.....SEETLAEIA.QGTEE.DVKEAVAAAKN.AMK.......E...M.NTLSAYD-
Q95TY8_DROME/95-558YTMDTQ...........RVCCPH....HLQTNLAHVY.YANRK.QIEAAIKSALS.AQG.......T...W.SLVPIAQ-
Q8ZV31_PYRAE/12-467FIEVEE.......RR..PKHSPI.....DGSVIAETP.VSKRE.DAKAAIDAAYD.ALK.......A...W.SQLPAIK-
Q6MQ98_BDEBA/11-457FVPSDS.......QKTFAKISPF.....DGTELARVT.ASDAM.DVIKAIQSAKK.AAP.......V...M.KDMPLSD-
Q9AH09_RHOER/16-479LTPSST......GAT.FDSINPA.....DGSHLASVA.EATAA.DVARAVEAAKAAART...........W.QRMRPAQ-
Q6F9F7_ACIAD/12-472FEDGAA.......Q..FDSINPA.....TGEIWAKMP.EARTD.QVNRAVDAAEQ.AFYD.....SS...W.SGLTASQ-
Q70Q17_RICRI/17-471FIEF.........GKQISVINPA.....TLKEIATVP.NLGLS.EINSAINNTVT.SFA.......L...W.SQSSFEA-
Q92UV7_RHIME/21-480LVDTDD......R...VEVRYPW.....NDTVVGTVP.AGRAE.HAREAFAIAA..AYQ.............PKLTRYE-
Y4UC_RHISN/49-507LHMTTS......LAP.IAVHSPY.....DGSLLGSVE.ATDPA.DIDRLLATARR.GAE.......I...S.RNLPRHK-
Q6MMT9_BDEBA/20-477FLKGSG.......LA.MDVVSPY.....NGQIIGNLH.ASTAK.DIDLAIKDAHE.TQK.......S...W.ADVPLKE-
Q703Z2_THETE/51-524YTSGK...........FEKRSPF....DTSIKIGTFQ.RGTPE.EFKAALSKAVE.AFP.......E...W.SRLDWRE-
Q73Y73_MYCPA/6-480WISADEGPRRTVSTT.IPVFNPS.....TEEQIAEVP.DSDQA.AVDAAVARARE.TFEL.....GV...W.RKAPASH-
Q8FS05_COREF/26-487ITSEAT.......PT.IPVEAPF.....DATTIGHVP.EGGQS.CVDKAFSLARE.AQR.......G...W.EDTPHAT-
Q93P88_9BACT/17-480WIDATT.......GESQEILSPT.....DETVVGTVQ.MGVEA.DAQIALEAAER.AQK.......Q...W.KKVPARK-
YF19_SCHPO/31-493HVDSVH......GGR.VKVYSPS.....TEKLICEVA.DADEE.DVDIAVKVARA.AFQT....DAP...W.RKFSSAQ-
Q8FS49_COREF/31-498WVTATG.......EKRNPVVDPA.....TGQEWGSVP.EAGQV.ELDHAVGAARE.ALP.......G...W.GSLTAAD-
O34184_HALVO/20-485WTESES......GES.IAVEDPS.....TRETVAHVP.RGTEA.DVDAAYEAAAE.AQE.......S...W.AEAPPAR-
ALDHX_YEASX/49-508KHNLFL.......EKIFSDYQPF.....KHDNRTQVSCSQHMR.DYRPLLTLSSATRSVLFSLLASD...MSIILSISP-
Q9KC36_BACHD/16-473WQHGQQ........S.IEVIDPG.....TNHVIATVP.AATEA.DAKAAIEAAKE.GAE.......I...A.RQMPIHE-
Q721Q0_LISMF/21-482WTDGDN.......KETKDIVNPA.....NGEVIAKIA.QAGPN.ETKKAIKAAKE.AFP.......D...W.AKMELAD-
Q6FDG9_ACIAD/11-475WRLGRG.......KV.IQSTFPA.....DNSVNAEIS.TASFE.DIEEAIVKADQ.AWRA.....PE...W.RNRLPHE-
PUUC_ECOLI/28-489YTAAAE......NET.FETVDPV.....TQAPLAKIA.RGKSV.DIDRAMSAARG.VFER.....GD...W.SLSSPAK-
ABDH_ECOLI/11-470LVSGEG.......EK.QPVYNPA.....TGDVLLEIA.EASAE.QVDAAVRAADA.AFA.......E...W.GQTTPKV-
BADH_AMAHP/16-485WREPIK......KNR.IPIINPS.....TEEIIGDIP.AATAE.DVELAVAAARR.ALKR.....NKGEDW.ASASGAH-
O24829_ACISP/12-482YVGSAS......GKL.FDNVNPA.....NGKLISKVH.EAGRE.EVDAAVNAAKA.ALR......GP...W.GKMTLEE-
Q7UFE0_RHOBA/24-485WRDSAS......GKT.FATINPA.....TEEEIVQVA.EGDKE.DIDAAVKAARK.AFES.....GP...W.RTMDARD-
P83849_THETH/46-512WV..DT......KER.MVSLNPS....APSEVVGTTA.KAGKA.EAEAALEAAWK.AFK.......T...W.KDWPQED-
Q73RK8_TREDE/20-482YIPSEN......GSI.VDVINPV.....NNLPFAKAY.RGTKT.DCEKAIAAARK.AFDE.....GP...Y.RKMSAKD-
Q6L285_PICTO/9-471WRDSSS......GET.IKKYNPS.....TGEVLDTFP.AATRN.DVDAAIDSAED.AFK.......R...W.SDMTSME-
Q82K12_STRAW/25-486FAKGTS......GRR.HAVVDPA.....TGEEVYRYE.LAGTA.DVDAAVAAARA.AFP.......G...W.AATTPGD-
Q6G1A0_BARQU/13-473WDDPST......PHD.LHVIDPS.....TEEVCAVIS.VASTK.DADKAINAAKA.AFQ......N....W.RTTLPNE-
Q7S5U4_NEUCR/22-482FVEASD......KGT.FNVVNPA.....TGEMSCKVP.EATED.DTNRAVAAAKA.AQP.......G...W.AALDPAK-
Q88LI4_PSEPK/30-488YVSPES.......EEYIHEFIPT.....TALPGDSIA.RGSAA.DVDKAVRAAAA.AQP.......A...W.NARKPIE-
O85031_9RALS/11-472WSASSD.......KKSFDRKHPV.....SGEVVTQCA.NATVD.DAVNAARAAQE.AFK.......S...W.KAVGPSE-
ALDH1_BACSU/18-484WVKSQS......GDM.VKVENPA....DVNDIVGYVQ.NSTAE.DVERAVTAANE.AKT.......A...W.RKLTGAE-
Q7UYE1_RHOBA/30-491HYPSEQ......GNV.LATIDPG.....SGDQLAEIH.DLNAA.EIDRAVEIANE.AFP.......A...W.AGLSQQE-
Q74E56_GEOSL/13-471WTGDD........RPGIEVVNPY.....DDSVIGVVP.EATNE.DVDHAIRAAQA.GFA.......E...M.SALPAYR-
O85973_SPHAR/26-487WIAGDS......GKT.IDLLNPS.....TGKVLTKIQ.AGNAK.DIERAIAAAKA.AFP.......K...W.SQSLPGE-
Q7WBK1_BORPA/13-471WQDGGE......P...VALYNPS....DLQEEAGVYM.HAPVE.MVNQAVRAAEE.ALD.......A...W.RGLHAMA-
Q6FBY4_ACIAD/20-482KLDVN........QT.FQDINPC.....DEILIAHIP.KASVE.DLNAIVAVAKQ.GLNS.....TA...W.HEVTPLQ-
Q8FY44_BRUSU/28-490WVGSDS......GKS.IERVAPG.....HGVTVSRYP.AGNKA.DVERAVSAARK.AFDD.....GR...W.SSTTASQ-
IOLA_BACSU/15-477WVESKT.......DQYEDVVNPA.....TKEVLCQVP.ISTKE.DIDYAAQTAAE.AFK.......T...W.SKVAVPR-
Q6SF25_9BACT/16-478WVDGGA.......GR.IDVINPG.....TGEKIAEQA.LADAR.DVDLAVQAAKR.VHST.....GV...L.TDMRPVE-
Q6BPC7_DEBHA/15-474IATSNL..........YPVYSHK....HAQDKICDFSYLSDYEKQIPEICDHAEK.GLE.......E...W.SSMPFTE-
Q828R7_STRAW/13-460WRPAAG.......PDMIEVVNPA.....DEQVIGRVP.AGTPE.DVDAAVRAARA.ALT.......A...W.AATPPAE-
Q7NEN1_GLOVI/15-481WQPAQS......GET.LEDLNPA....DRREVVATFP.RSGAA.DVEAAVTAARK.AYR.......G...W.RLVSAPA-
ALDY_BACSU/15-474WTGGES......GRT.EDILNPY.....DQSVITTAS.LATGK.QLEDAFDIAQK.AQK.......E...W.AKSTTED-
Q47943_GLUOY/25-486W...RAG.....KDF.FDRSSPA.....HDVPVTRIP.RCTRE.DLDEAVAAARR.AFEN.....GS...W.AGLAAAD-
Q75TI0_GEOSE/8-466WSKGEG.......KK.RPVINPA.....NEEIIIEIN.EASQQ.QAVEAIQAARH.AFQY.....TD...W..PFNPAK-
Q8TWC7_METKA/11-466WLEGD.........REIVVENPY.....DGSEVGRV..LAPEV.DVEALLKDARE.GQR.......R...W.RERPTYE-
Q59095_ACICA/18-473WQSAQD......T...YSVIEVA.....TGQVLGEIG.YATAA.DVVSAAQQAKA.AQQ.......Q...W.WALNYQE-
ROCA_BACSU/45-511KI..ET......DRK.IISINPA....NKEEIIGYAS.TADQE.LAEKAMQAALQ.AFD.......S...W.KKQRPEH-
Q7WPN3_BORBR/33-490IVPGNG.......AM.IEVLDAS.....TGEPLFRYL.DGSDG.LVRRAAESAAAAQVR...........W.AVMPADG-
ALD1_STAAS/13-470WVESNS......NET.IEVINPA.....TEEVIGKVA.KGNKA.DVDKAVEAADN.VYL......E....F.RHTSVKE-
O50203_XANAU/26-493FVEPVG......GRY.FDNTSPV.....TGGKICEIA.RSDAD.DIEKALDAAHA.AKD.......A...W.GKTSAAV-
Q6W1I3_RHISN/34-497WSDSSN......GAT.FDIFEPS.....TGGLITRAP.SGTPE.DLDRAVRAARR.QFDG.....GA...W.RRLKPLE-
Q7VSP3_BORPE/17-482WVACAA.......GKTYPNVNPA....DTDDIVGRFQ.ASQAE.DAAAAVAAAQA.AFD.......G...W.RNLAVSK-
Q9L124_STRCO/18-473W.QGSP......T.E.QPVTEPA.....TGDRLGTVG.LASAE.DVNRAAARAAE.AQR.......T...W.AATSPQR-
Q6JHN1_9PSEU/12-470LVEGP........ET.LDVLDPS.....TGTLLDRTL.RGTGE.HVDAAVAAARAASRE...........W.AHTPYSE-
BADH_SCHPO/29-495FVSPIEP....AAKP.IPLINPA.....TEEIIGTCA.NASAK.DVDSAVENAYN.TFRS.....GI...W.AKWPGKQ-
Q59702_PSEPU/20-480WRVGKA......GRD.LDVLDPF.....TQEKLLQIP.LANRE.DLDEAYRSARQ.AQV.......A...W.AACGPSE-
MSC7_YEAST/104-587WNPEEP.......NF.IQCHCPA.....TGQYLGSFP.SKTEA.DIDEMVSKAGK.AQS.......T...W.GNSDFSR-
Q73WS7_MYCPA/19-482WVEPQD.......GR.YDDLSPS.....TEAVIATAP.DASVA.QVDDAIAAARR.AFDS.....GP...W.GRMSAEQ-
GAPN_PEA/24-484WKKSTS.......GKSVAIINPT.....TRKPQYKVQ.ACSQE.EVNKVMDSAKS.AQK.......S...W.AKTPLWK-
Q6MF92_PARUW/536-989FHYTSE.......NRWGIGEDPS....FPGKILYRYA.LASKE.QVDEALDAAQNAYLK...........W.SATTSQE-
Q8CN25_STAES/16-475FIESQS.......KETMDVINPA.....TGEAFDTIT.LATEE.EVNDAIEKSQQAQLE...........W.ERVPQPT-
O87842_STRCO/48-500WRAD.........GRVLPATSPV.....DGTPIAGPP.RIDAA.TAHRAVRASLD.QHR.......A...W.RHVPLPE-
AL7A1_DICDI/28-492W..GGA.......GEIIKCLNPT.....NNKVIATVR.GAAPE.EYETCIQAMLA.AKV.......K...W.ALTPAPR-
Q6CRD2_KLULA/26-495YVEAHG......SET.LTSYNPS.....SGEEICKVQ.CADPKIDVDLAVKAARD.AFP......G....W.KATPAIE-
Q885F4_PSESM/28-486FIEGHG.......AP.VEVRNAH.....NDSLLLSFP.DADES.LVEVADKAAKA.AQQ.......Q...W.WAMTAQA-
Q6AKR4_DESPS/50-520WISPAG.......SKVIESISPV.....DGRIIAKIQ.AGGAP.EYKRIITQAQK.AFP.......L...W.RKIPAPE-

PF07368

Q9VAW6_DROME/82-298------------------------------------------------------------------A---W---------
Q9VYG8_DROME/38-250------------------------------------------------------------------Q---W---------
Q9W2S6_DROME/22-243------------------------------------------------------------------V---W---------
Q8T485_DROME/35-252------------------------------------------------------------------A---W---------
Q9W1T5_DROME/37-260------------------------------------------------------------------S---W---------
Q9V9P6_DROME/64-279------------------------------------------------------------------V---T---------
Q9VI33_DROME/97-311------------------------------------------------------------------Q---W---------

PF00815

HISX_ECOLI/17-428----------------QRQLLMRPAISASESITRTVN-------DILDNVKARGDEALR-------------EYSAKFD.
HISX_BACSU/10-423----------------ERLSLKRSIDAGTEEQRKTVR-------SIIEDVKANGDQAVR-------------SYTAKFD.
HISX_ARCFU/2-402----------------EEILRLRRSVSIDD.YIEKVK-------PIVEAVKREGDKAVI-------------RFTRDLD.
HIS2_NEUCR/445-864----------------LDAALKRPAQKSSDAIYKIIV-------PIIEDVRKNGDKAVL-------------SYTHKFE.
HISX_METTH/13-425----------------ISELVERARLDVDD.VLGPVA-------DIISMVRDGGDDALR-------------ELTGRFD.
HIS2_PICPA/422-837----------------IEDALRRPIQKTEQ.IMELVK-------PIVDNVRQNGDKALL-------------ELTAKFD.
HISX_HAEIN/14-423----------------KRKVIMRPVQQNGKNIQQAVN-------AIRENVAYNGDRALF-------------ELCEKFD.
HISX1_SYNY3/15-432----------------LNQLKRRSEQNIDQ.ALAIAK-------EVIEQVKMEGDAGVL-------------HYSRQFDF
HISX_STRCO/18-434----------------LRDLLPRADFDVSV.ALEKVR-------PICEAVHHRGDAALI-------------DFTEQFD.
HISX_BRAOC/46-459----------------VENLKARPRIDFSS.IFTTVN-------PIIDAVRSKGDTAVK-------------EYTERFD.
HISX_BUCAP/18-429----------------QKNILLRPVIKNNNSIKKKVK-------KIIENIQVLGEKALR-------------EYTILFE.
HIS2_KLULA/366-785----------------VEKAVTRPIQKTAE.IMNLVN-------PIIENVIKNGDKALV-------------ELTAKFD.
HISX_MYCSM/24-444----------------LRSALPRGGVDVDA.VVPKVR-------PIVDAVAQRGAQAAL-------------EYGESFD.
HISX_AQUAE/18-425----------------EYLAKRGEILE..EEYEKSVK-------EILKRVREEGDRAVI-------------EFTKKFD.
HIS2_CANAX/412-832----------------VERAMTRPVQKTAD.IMKLVL-------PIIEKVKSDGDKALI-------------ELTSKFD.
HISX_METJA/18-429----------------EEKIINRNKANFEE.ILPTVM-------EILKDVKEKGDEALK-------------YYTKKFD.

PF05893

Q8G6W7_BIFLO/65-480-RRQAELLIPAITG-YEPDMVRIELKR...YMRQFRRRELL---RFLDSEI.-GQ-----PSMLDEFR..--PNK-----
Q7MZU4_PHOLL/30-413-........AVKLA-LDTAALTA.......LRHFCHRDSLE---AKLRHELG-EQ-----PFSLRRFD..--YTQ-----
Q7NQ23_CHRVO/30-413-........ERHPL-LDEPGRAQ.......LAAFCRREALQ---AKLERELG-ER-----PFSLRRPD..--YRE-----
Q3KD56_PSEPF/30-413-........DMAMP-IEPEQRQA.......LIGFCQPDALR---RKLERELG-EQ-----PGSLRRLD..--YRQ-----
Q93CP6_PHOLU/52-446-RRTYIRDLKKYMG-YSEAMAK..LEANWISMILCSKGGLY---DVVENEL.-GS-----RHIMDEWL..--PQD-----
LUXC2_PHOLE/50-444-RLTYIRDLIKFLG-YSQEMAK..LEANWISMILCSKSALY---DIVENDL.-SS-----RHIIDEWI..--PQG-----
LUXC_VIBFI/51-445-RRTYIRELKTYLG-YSDEMAR..LEANWIAMLLCSKSALY---DIVNYDL.-GS-----IHVLDEWL..--PRG-----
Q4A539_9GAMM/49-442-RRTYIRDLTNFLG-YSNEMAK..LEANWIAMLLCSKSALY---DIVQHDL.-GS-----LHIIDEWI..--PQG-----
LUXC_VIBHA/49-443-RRAYIRSLITYLG-YSPQMAK..LEANWIAMILCSKSALY---DIIDTEL.-GS-----THIQDEWL..--PQG-----
A8LEK2_FRASN/68-470-MQDCIDRMAGTHV-LPRAVLEGQVKG...AAAYLDKRLLE---TVVEQNF.-PD-----PRALDEWVPK--QDF-----
Q97GS8_CLOAB/45-446-K..HIETLAQITN-QSFELVNYEFKS...MMQMLLRENIQ---NTIKREL.-GE-----VDILDSWH..--KTN-----
A6LV85_CLOB8/35-425-........RKFLS-YEGVPF.........LVLWLKKDNIK---KLLHQDL.-KK-----QEFLDDFI..--EIA-----
Q9KV99_VIBCH/423-818-........PELDP-YRHTGLNF.......LADWCEPNRLK---NLLDSALN-GQ-----RAFLDNFL..--PRK-----

PF00171

Q7CTQ3_AGRT5/29-491-RKAILLTFAKLLE.QHRHELAV-------MESLDSGKPVS...ECQTVDIP.DT.....IHTIRWHAEL..IDK.LYD.
Q7CSM1_AGRT5/15-474-RSKIMRKAADILR.ERKDKIAY-------IMTREQGKPLA...QSAT.EIM.GA.....ADTIDWFAEE..ARR.TYG.
Q7D3N3_AGRT5/14-476-RARVLDQMASAIE.RNRERLID-------ILSLENGKLLG...EAAL.EID.GS.....PSKLRYWAAM..ART.EAG.
Q7CVT1_AGRT5/28-485-RGDILRNWSARMR.ENAHDLAT-------IISAEQGKPLA...ESRG.EIA.YA.....ANFLDWFASE..GER.SYG.
A9A1B_DANRE/49-507-RARVMLEAARLIE.KRREEIAE-------MEVINNGKSIT...EARL.DVD.SA.....RLSIEYFAGQ..ATT.LSG.
BETB_ECOLI/15-479-RSRILRRAVDILR.ERNDELAK-------LETLDTGKAYS...ETSTVDIV.TG.....ADVLEYYAGL..IPA.LEG.
ALDA_ECOLI/18-475-RASWLRKISAGIR.ERASEISA-------LIVEEGGKIQQ...LAEV.EVA.FT.....ADYIDYMAEW..ARR.YEG.
ASTD_PSEAE/10-467-RIELLERFAATLK.SRADELAR-------VIGEETGKPLW...ESAT.EVT.SM.....VNKVAISVQA..FRE.RTGE
ALDH6_YEAST/34-496-RGRLLSKLADELE.SQIDLVSS-------IEALDNGKTLA...LARG.DVT.IA.....INCLRDAAAY..ADK.VNG.
CROM_ENTDO/24-487-RGHLLYRLADLFE.RDIAYLSS-------LETLNTGKPYK...SAYQ.DIV.HC.....IQVLRYYAGW..ADK.NMG.
O66573_AQUAE/12-471-RYEILMRAAQLLK.ERAEEFAK-------TLVLEVGKTIR...EART.EVQ.RA.....IQTLIFSAEE..AKR.VNG.
Q6BX25_DEBHA/48-514-RSDLLMNLYRLMQ.ENQDDLAK-------LIVLENGKPYA...DAFG.EVA.YA.....SSFFQWFAEE..APR.VYG.
Q93HF8_STRAW/48-523-RMRLGTRFREELL.KHQDEFLD-------MLVAE.SHPVK...LARW.ELS.CLLQIYAPGSLRWYMKQMRVEK.....
LADH_METJA/7-459-RYNILMNIAKQIK.EKKEELAK-------ILAIDAGKPIK...QARV.EVE.RS.....IGTFKLAAFY..VKE.HRD.
Q739I7_BACC1/23-485-RSNILCKMSDLIM.ERVDELAY-------IETLDVGKPIK...ESKGFDIP.RS.....AHNFRFFAEM..AKYIVHE.
O33455_PSEPU/24-488-RGRILENVARKIE.EHADELAY-------LESLDTGKALT...FAKAIDLP.ST.....IDVFRYMGGW..CSK.LGG.
O86742_STRCO/16-473-RQKALLKIADAFE.ERAEELIA-------AEVENTGKPIG...LTRSEEIP.PM.....VDQIRFFAGA..ARM.LEG.
Q7W0D6_BORPE/10-472-RADVLDAVGTELL.ARKEELGR-------LLSREEGKTLP...EGVS.EVT.RA.....GHIFKFFAGE..ALR.IQG.
O52642_9PSED/19-476-RAAIVRMAAEKLK.EREHEFAD-------WNVRECGAIRP...KGLW.EAG.IA.....YEQMHQAAGL..ASL.PNG.
Q7UJE5_RHOBA/56-500-RCQIVGRARDEIA.SRVDQLTR-------LSRSEQRTDDA...ETVASELIPL......CDALRWIGKH..GRKTLAPR
Q98LH9_RHILO/20-482-RAEVLNRLADLIR.TNRDRLVR-------IEVEEVGKPVR...FARG.DID.GA.....AGLTRYAASL..AMQ.MAGL
Q6ABP5_PROAC/22-479-RAEILRKTFNLVT.ERKDDFAR-------LMTLEMGKPLA...ESYG.EVT.YG.....SEFLRWFSEE..AVR.IRG.
Q6ALY1_DESPS/13-480-RVQIFFRMKMLVD.QHLEELTD-------ILCREQGKNRA...ESMG.DVL.KV.....NEVIEFACGA..PHL.MKG.
Q82GU8_STRAW/29-495-RAAVLGRAAEVMR.RNLVPYAE-------LAQAESGATTG...TARGMQVG.VG.....AARFRRYARVEPAEEPIAP.
Q6N3D4_RHOPA/38-498-RRKLLHTIADAIE.ARADDIAV-------LECIDTGQAHR...FMAKAAIR..A.....AENFRFFADK..CAEARDG.
ALDA_STAAS/21-483-RAQMLRDIGDKLM.AQKDKIAM-------IETLNNGKPIR...ETTAIDIP.FA.....ARHFHYFASV..IET.EEG.
Q8A340_BACTN/495-936-RHRIMYEAANRLA.DMRGDLIG-------CMCAVTGKTVI...EGDV.EVS.EA.....VDYARFYTTAMKKFAALDDV
Q6PW33_9RALS/11-473-RGRLLLKLADAIE.ANADELAR-------LESMDTGHPIR...DTRNLDVP.RT.....AATFRYFGGM..ADK.FEG.
BETB_BACSU/11-476-RGKIVLKIAELIR.RDLEELAE-------LESLDTGKTLE...ESKA.DMD.DI.....ANVFQYYAGL..ADK.DGG.
P74275_SYNY3/509-973-RCGILRKAADIME.ERRHELNA-------WICLEVGKIIP...QADA.EVS.EA.....IDFCRYYADE..MER.LD..
O06837_PSEFL/29-498-RERILLRLADLLE.AHGDELAR-------LETLNNGKLLI...YSKMMEVG.AS.....AQWLRYMAGW..ATK.LTG.
Q8GPZ0_PSEAI/20-479-RAQLVEALADELL.KRADDLSL-------AVSLSIGRPAA...QANEAHRF.KA.....VTLAQIEA....LEE.LDD.
Q7WPE0_BORBR/13-475-RRDALDRLAKALR.QRAPDIVA-------GLAREIGCPVW...LGELMQVP.MA.....MKGMAHARDG..MDA.IAWR
Q6AA40_PROAC/499-947-RAEILRTVTHAFA.TRRGDLLA-------VAGAETGKILA...EGDV.EVS.EA.....IDFAAWYVDR..AEE.LEGV
P96405_MYCTU/17-478-RAAVIAAAVKMLA.ERKDLFTK-------LLAAETGQPPT...IIETMHWM.GS.....MGAMNYFAGA..ADK.VTW.
Q8ELI8_OCEIH/14-471-RSKILKKAAYLLE.ENKEKFAK-------LLSSELGKPLK...DTLG.EVD.RS.....IETLELSGEE..AKR.LHG.
Q9RZE6_DEIRA/24-482-RGKILRRWHDLMF.EHKEELAQ-------LMTLEMGKPIS...ETRG.EVH.YA.....ASFIEWCAEE..AGR.IAG.
AL1L1_HUMAN/430-898-RGRLMYRLADLME.QHQEELAT-------IEALDAGAVYT...LALKTHVG.MS.....IQTFRYFAGW..CDK.IQG.
ALDH5_BACSU/16-474-KRTILEKAVTYIE.ENEEAIIY-------LIMEELGGTRL...KAAF.EIG.LV.....KNIIKEAATF..PIR.MEG.
Q97UA1_SULSO/11-474-RGSILLKAGELME.QEAQEFAL-------LMTLEEGKTLK...DSMF.EVT.RS.....YNLLKFYGAL..AFK.ISG.
Q92XQ0_RHIME/15-479-RGRIIQRFAALIE.EHADALAD-------IEVRDNGRLLA...EMTH.QIR.YI.....PRWYHYYAGF..ADK.IEG.
O24897_HELPY/516-965-IHALMSQTAQLFR.ERRGDLIG-------ISALEVGKTFA...ETDA.EVS.EA.....IDFLEFYPYS..LRV.LQEQ
Q18822_CAEEL/36-498-RSALLNKVANLIE.EFNDDIAI-------LESRDQGKPIG...LAKVMDIP.RC.....VQNFRDFANA..ALYSLSTS
O49218_ORYSA/49-511-RQRIMLKFQELIR.ANMDKLAE-------NITTEQGKT.E...GCLG.RCF.RG.....LEVVEHACGM..GTL.QMG.
Q8KVX3_9RHOB/30-494-RLAVIERFSALIE.ENAVEFAL-------LDCLDMGKPVM...DMINIDIP.ES.....VKNLKFFAET..ADK.VHG.
Q20352_CAEEL/214-676-RSEILKKTGDLLK.THCNDIAY-------WECISNGKPIA...EAKA.DVL.SC.....VDTFYFYSGI..ASD.LLG.
Q88PZ0_PSEPK/11-471-RAAFLRGFAEQLG.QRREALVT-------VQMRNNGKPRH...EAEI.DLD.DA.....IATFGYYAEL..AEQ.LPS.
Q881E4_PSESM/24-482-KAEIFLMAADHAV.CAFDELAL-------YVARETGGSLH...KGQH.EVN.ET.....IVLLRQAAGMLSQAH.GHG.
Q6HJ76_BACHK/11-470-RATILEKVAQKMD.ERREEFAE-------IIAKEAAKPIR...AARG.EVD.RT.....VQTYKFAAEE..AKR.IYG.
Q95TY8_DROME/95-558-RLAIWRRAATIIEED.ELRLRV-------FLMMTLSKTAD...DATR.DIR.RL.....LTSLRANADY..LEH.LSEL
Q8ZV31_PYRAE/12-467-RAEYLYKLYEIIK.SREEELIN-------ILMVEGGGIYK...KAWG.EVV.FT.....ERLVRNAAEL..ARH.YGG.
Q6MQ98_BDEBA/11-457-RASLLLKLASALE.EKSDDCAY-------QEALHQGLPQS...FVLEHSLR.PA.....IRILKEVAGS..LNQPLSA.
Q9AH09_RHOER/16-479-RTRLMFRYAALIE.EHKTELAQ-------LQSRDMGKPIR...ESLGIDLPIM......IETLEYFAGL..VTK.IEG.
Q6F9F7_ACIAD/12-472-RGKLLYKLADLVE.KSAPRLAA-------LETTDTGKIIR...ETSS.QIA.YV.....AEYYRYYAGL..ADK.IEG.
Q70Q17_RICRI/17-471-RIAILRRWYNLVI.ENIEELSH-------ILTLEQGKVLA...ESKK.EIL.YG.....ASFIDWYTYA..IHN.IHS.
Q92UV7_RHIME/21-480-RQKILLATAEALA.ARKEEISD-------VITLELGISKA...DSLY.EVG.RA.....FDVFTLAGQM..CIR.DDG.
Y4UC_RHISN/49-507-RASILEGAAQMVE.SRHDAFAE-------IIVREAGKTIV...QARK.EVL.RC.....VNTLKLSAEE..AKR.NAG.
Q6MMT9_BDEBA/20-477-RTKIMFNFRQILM.RDLDEIAH-------LKSSESGKTFA...EGKA.GLM.KG.....IEVLEFALSL..QNM.DLG.
Q703Z2_THETE/51-524-RARILAKLADLIE.RDRFKLAA-------AITYEVGKNRF...EALA.EIH.EA.....IDVLRYYVEL..IHK.MDG.
Q73Y73_MYCPA/6-480-RANVLFRAARIIE.ERKDELAA-------LESQDNGMNLT...AAGHI.IP.VS.....VDMLKYYAGW..VGK.IHG.
Q8FS05_COREF/26-487-RRSIVRTFHSLVL.KHRELLMD-------MVQLETGKNRA...AAFD.EVM.DV.....ASTARYYAAR..AEKLLTPR
Q93P88_9BACT/17-480-RADLLRTFAAEIK.ANKNQLAE-------LLVREQGKLLA...VAKM.EVE.VT.....ASFIEYACDG..ARS.IEG.
YF19_SCHPO/31-493-RGRCLSRLADCIE.QNLEYLAS-------IETLDNGKSIT...LARG.DVQ.AA.....ADCFRYYGGW..ADK.DYG.
Q8FS49_COREF/31-498-RAEYLVRIAEEIE.KRAEVLAL-------TNTRENGSPIS...ETRGAAAN..A.....AGIFRYFATL..APF.LDDP
O34184_HALVO/20-485-RQEVVEQFLQALN.EYEDEIID-------LLAHEVGGSRI...MGET.SIQ.IA.....SDHASEAATL..PRR.MRG.
ALDHX_YEASX/49-508-NTGILLCIGHLLA...SDIEDV-------VIVLSRGSPLVDLASTRIFKLA.Q......NGTLRFAI....KRTTFQEL
Q9KC36_BACHD/16-473-RAAILKRTAEIVT.RDRELFAQ-------TIAKEGSKTIR...EARS.EVR.RC.....IETLTLSGEE..AKR.LHG.
Q721Q0_LISMF/21-482-RVKLLHKIADLME.EKADTLAK-------IMTLEQGKPLK...ESKG.EVL.TG.....AENFRFAAEE..ARR.LYG.
Q6FDG9_ACIAD/11-475-RAKILYKVADIIE.ARVDALAA-------LQTRDNGKPLA...ETRG.LVF.SA.....AATARYVAAA..CET.MND.
PUUC_ECOLI/28-489-RKAVLNKLADLME.AHAEELAL-------LETLDTGKPIR...HSLRDDIP.GA.....ARAIRWYAEA..IDK.VYG.
ABDH_ECOLI/11-470-RAECLLKLADVIE.ENGQVFAE-------LESRNCGKPLH...SAFNDEIP.AI.....VDVFRFFAGA..ARC.LNG.
BADH_AMAHP/16-485-RAKYLRAIAAKIT.EKKDYFAK-------LEAMDCGKPLD...EAAR.DID.DV.....AGCFEYYADQ..AEA.LDA.
O24829_ACISP/12-482-RTSILHKVADGIN.ARFDEFLK-------AECLDTGKPKS...MASHIDIP.RG.....AAHFKVFADM..IKN.....
Q7UFE0_RHOBA/24-485-RGRLMMKLADAIE.NEIDELAQ-------LETLDNGKPLR...ESRHADLP.LV.....IDALRYYAGY..ADK.IQG.
P83849_THETH/46-512-RSRLLLKAAALMR.RRKRELEA-------TLVYEVGKNWV...EASA.DVA.EA.....IDFIEYYARA..ALR.YRY.
Q73RK8_TREDE/20-482-RSKLLLKAAQILE.RRAEELAV-------IETLECGKNYS...ACRYWEVP.MA.....IDSFEFFAGK..ARC.LDG.
Q6L285_PICTO/9-471-RSKILYKALELIS.KDKDQLTD-------LLIKENGKVKR...EAMD.ETE.GV.....IDQLQYYTEF..ERK.LTG.
Q82K12_STRAW/25-486-RSDALHRFAAVLA.DRAEEFAR-------AESLQCGKPLK...LTREFDVP.GT.....IDNTSFFAGA..ARH.LQG.
Q6G1A0_BARQU/13-473-RLSFVEKILEIYE.KRSEDMAK-------TISMEMGAPID...MALNAQTA.TG.....SSHIRNFIKV..YKE.FTF.
Q7S5U4_NEUCR/22-482-RGAYLKKLAALIR.EHKSTLHH-------LEAISMGVPVN...HFFHADFG........ADELDYFAEA..WPH.IQG.
Q88LI4_PSEPK/30-488-RGRILLAIARLVR.ANAAAFCA-------KEAEETGKPLK...MAAF.EIE.AC.....AQYFEYYGGL..ATA.IQG.
O85031_9RALS/11-472-RRRLLLKVADVME.SKTPEFIE-------VMAKEVGASAL...WAGF.NVH.LS.....ANVFREAASL..ATQ.IQG.
ALDH1_BACSU/18-484-RGQYLYKTADIME.QRLEEIAA-------CATREMGKTLP...EAKG.ETA.RG.....IAILRYYAGE..GMR.KTG.
Q7UYE1_RHOBA/30-491-RSSILLKLADAVE.SHKAIIAQ-------IEALDAGKIEA...QAAG.DVQ.NF.....VDTMRYFVGL..SDK.VEKR
Q74E56_GEOSL/13-471-RSDILDRTSELIK.RDREEIAE-------IIAREAGKSWK...FALA.EAD.RS.....AETFRFASLE..ARN.AHG.
O85973_SPHAR/26-487-RQEILIEVARRLK.ARHSHYAT-------LETLNNGKPMR...ESMYFDMP.QT.....IGQFELFAGA..AYG.LHG.
Q7WBK1_BORPA/13-471-RSRLLDGIADGLV.GRRDELAM-------AIAREQGKPLR...DALA.EAT.RA.....ADIFRYFASE..TIR.QKG.
Q6FBY4_ACIAD/20-482-RENLIRCFADAIE.KDSTRLAQ-------LESIDAGKPIS...ITQTVDIP.AV.....VAWLKYYAGW..ASK.IMG.
Q8FY44_BRUSU/28-490-RSLVLLKAADLIE.ARAEELAY-------LDAIEAGKPIS...QVRG.EIS.GS.....VDIWRYAAAL..ARD.LHG.
IOLA_BACSU/15-477-RARILFNFQQLLS.QHKEELAH-------LITIENGKNTK...EALG.EVG.RG.....IENVEFAAGA..PSL.MMG.
Q6SF25_9BACT/16-478-RGRIVQAMGRYLL.EHLEEIAA-------LLSLEQGKPIW...EARI.EVT.GA.....ARYFEYYGNQ..AET.LEG.
Q6BPC7_DEBHA/15-474-KRSILKKALELLA.AKRDELVE-------AHKL.IGGPTW...FSEF.NVE.GA.....IGQLEEYISQ..LSQ.PDG.
Q828R7_STRAW/13-460-RAARISALRDVLV.ARQDEIAE-------TVTAELGSPLS...FSQSVQVG.LP.....ILVAGSYAEL..AAT.YAFE
Q7NEN1_GLOVI/15-481-RAEIVFRIGEILR.GRKEALAQ-------LMSREMGKTIV...EARG.DVQ.EA.....IDCAFYYAGE..GRR.LFG.
ALDY_BACSU/15-474-RKAVLQKARGYLH.ENRDDIIM-------MIARETGGTII...KSTI.ELE.QT.....IAILDEAMTY..TGE.LGGV
Q47943_GLUOY/25-486-RAAVLLKAAGLLR.ERRDDIAY-------WEVLENGKPIS...QAKG.EID.HC.....IACFEMAAGA..ARM.LHG.
Q75TI0_GEOSE/8-466-RIAALRQLADLLE.QNAETFAS-------IETLNTGKPIR...ESRL.DVS.DS.....IQCLRYYADF..VEQ.RAI.
Q8TWC7_METKA/11-466-VREALAEAAHLLK.KHEDELAE-------LIALEGGKPIR...DARY.EVY.RT.....REVLRLSAAE..AER.LYG.
Q59095_ACICA/18-473-RQAVFERAAALLT.ENQAEVIE-------WLVKESGSLQL...KAGF.EVS.IA.....IQVLKHCIAS..PTN.EQG.
ROCA_BACSU/45-511-RANILFKAAAILR.RRKHEFSS-------YLVKEAGKPWK...EADA.DTA.EA.....IDFLEFYARQ..MLK.LK..
Q7WPN3_BORBR/33-490-RAAVLLAVSAAIR.ANLARLAE-------LEAVTAARPIR...DCRA.QVD.RV.....ADMFQYYAGW..CDK.FYG.
ALD1_STAAS/13-470-RQALLDKIVKEYE.NRKDDIVQ-------AITDELGAPLS...LSERVHYQ.MG.....LNHFVAARDA..LDN.YEF.
O50203_XANAU/26-493-RALILNRIADRME.ENLDLLAL-------AETWDNGKPIR...ETTAADMP.LA.....IDHFRYFAGA..VRA.QEG.
Q6W1I3_RHISN/34-497-RERLLHSLADLIE.AHSDELAE-------IEAIDMGKSVT...FAREIDIR.GT.....VDTFRYFAGW..ASK.LHG.
Q7VSP3_BORPE/17-482-RAALMQRAADYLE.AHAEQFGR-------ELTREEGKALN...LAKD.EVL.RS.....AQTIRFYAAE..GQS.FSG.
Q9L124_STRCO/18-473-RAAVLRRAGELFT.EHAAEIED-------WLVREAGSVRS...KAAF.EAG.LA.....IGECFECAGL..PTH.PQG.
Q6JHN1_9PSEU/12-470-RSAILRRIGELIR.RDRGEFAL-------LESQDTGKPLA...QACA.DTD.VA.....ARYFEYYANT..MEA.FFG.
BADH_SCHPO/29-495-RGLVLRKIAKMMR.EKRELLAG-------IDTINCGKPTP...YALF.DID.SC.....ADMFEYYAEV..AET.....
Q59702_PSEPU/20-480-RAQVMLNAVRIFD.ERRDEIID-------WIIRESGSTRI...KAQI.EWG.AA.....RAITQESASL..PSR.VHG.
MSC7_YEAST/104-587-RLRVLASLHDYIL.NNQDLIAR-------VACRDSGKTML...DASMGEIL.VT.....LEKIQWTIKH..GQRALQP.
Q73WS7_MYCPA/19-482-RARCLNQLGEALT.KHADDFFA-------LSQTEWG.CIG...NERIMQID..G.....AGFMSLHAAQ..LATQLVDQ
GAPN_PEA/24-484-RAELLHKAAAILK.EHKAAIAE-------CLVKEIAKPAK...DAVT.EVV.RS.....GDLVSYCAEE..GVR.ILGE
Q6MF92_PARUW/536-989-RANLLIKIAQGLE.LHRADLIG-------AMIADTAKTLI...EADI.EVS.EA.....IDFANYYRFN..LLEWMYLE
Q8CN25_STAES/16-475-RAEHVKLLIPLLE.KNRDEIAQ-------LYVKEQGKTLT...QAYG.EID.KS.....ISFIDYMTSL..SMS.DKG.
O87842_STRCO/48-500-RRARVAATLDALA.QHRELLAL-------LLVWEIGKPWR...SARA.DVD.RA.....VDGVRWYLDG..IEDMLDG.
AL7A1_DICDI/28-492-RGEIVRLIGQAMR.EKIEPLSK-------LISLEMGKIYI...EAKG.EVQ.EF.....IDVCDYATGL..SRS.ING.
Q6CRD2_KLULA/26-495-KRDLFYKLAGLLE.RDIDILSK-------IESLDTGKPIA...NNAKYDIL.EV.....VEVLKYYAGW..IDK.AGG.
Q885F4_PSESM/28-486-RGRAMYQVGNLIR.EEQENLAQ-------IESLTANKPIR...DARV.EVL.KV.....AEMFEYYAGW..ADK.LHG.
Q6AKR4_DESPS/50-520-RGEIVRQIGEALR.KDKENLGR-------MICLEMGKSLQ...EGYG.EVQ.EM.....IDVCDFAVGQ..SRM.LYG.

PF07368

Q9VAW6_DROME/82-298-----------------------------------------------------NA-------------------------
Q9VYG8_DROME/38-250-----------------------------------------------------RS-------------------------
Q9W2S6_DROME/22-243-----------------------------------------------------KD-------------------------
Q8T485_DROME/35-252-----------------------------------------------------PG-------------------------
Q9W1T5_DROME/37-260-----------------------------------------------------IL-------------------------
Q9V9P6_DROME/64-279-----------------------------------------------------SS-------------------------
Q9VI33_DROME/97-311-----------------------------------------------------NS-------------------------

PF00815

HISX_ECOLI/17-428.KTT.VTAL..KVSAEEIAAASE-------RLSDELKQAMA------------VA-----VKNIETFHTAQK..LPPVDV
HISX_BACSU/10-423.CIE.IDSP..LVTKEEFEEAYT-------SLDSRLLQVIR------------QA-----IENIREYHERQLQSSWFYHR
HISX_ARCFU/2-402.GVE.LDSL..RVTEDEFEKAYD-------AVDDGLIDALE------------VA-----KENIYRFHYVTSVER.DMKV
HIS2_NEUCR/445-864.KATSLTSP..VLKAPFPKELMQ-------.LPEETIAAID------------VS-----FENIRKFHAAQKE.EKPLQV
HISX_METTH/13-425.GVT.VENF..RVSREEIEEAHK-------NLEPGVKEALR------------EA-----ASNIEEFHRMQMPSG.WMSE
HIS2_PICPA/422-837.GVA.LKTP..VLEAPFPEELMQ-------.LPDNVKRAID------------LS-----IDNVRKFHEAQL..AETLQV
HISX_HAEIN/14-423.GVK.LDKL..IVSADEIQAASS-------RISVKLRNAIE------------QA-----KTNIEAFHKAQQ..NQEIDL
HISX1_SYNY3/15-432AGAT.AENL..RVSEAEFAEAEK-------LVDPELRRAVE------------HA-----FRNIEKVHAGQMP.PPMHLA
HISX_STRCO/18-434.GVR.LERV..RVPAEELTRALE-------GLDPEVRAALE------------ES-----IRRARLVHREQR..RATHTT
HISX_BRAOC/46-459.KVQ.LNK...VVEDVSELDIPE-------.LDSAVKEAFD------------VA-----YDNIYAFHFAQM..STEKSV
HISX_BUCAP/18-429.KCH.INKF..EVSKEKMLSSSL-------YVNQSLKDAIS------------TA-----KKNITSFHTAQI..LSPIDI
HIS2_KLULA/366-785.GVQ.LETP..VLEAPYPEEYLD-------GLTDELRDALD------------LS-----IENVKKFHAAQMQ.SETLDV
HISX_MYCSM/24-444.GIR.PETV..RVPRELLSQALE-------NLDADVRAALQ------------VS-----IDRARAVHADQR..RTDTTT
HISX_AQUAE/18-425.GVE.LTPENMEVPFEELEKAYE-------EIEPEVREALE------------FA-----ENRIRVFHEKQLENSF..FK
HIS2_CANAX/412-832.GVK.LDAP..VLQAPFPADLMD-------.ISEEMKAAID------------LS-----MQNIEKFHAAQLPKEKVMTV
HISX_METJA/18-429.GVE.IEDF..KVTDEEIEEAYN-------SVDYKVVEAIE------------RA-----KENIYFFHKKQMEQIKDLNV

PF05893

Q8G6W7_BIFLO/65-480----------------------A..GGYSKYV-GP-ALTYQVFSSNVPGIP--VWSMAMTLLVKGAILGK-SSFSEPVMP
Q7MZU4_PHOLL/30-413----------------------P...RFETWQ-PL-GLVVHITPANAPLLP--FMAVLESLLVGNVNWLR-PSSSDHGLN
Q7NQ23_CHRVO/30-413----------------------P...RFEAWR-PL-GLVLHVTPSNAALLP--FMAALEGLLAGNVNWLR-PSSSDQGLS
Q3KD56_PSEPF/30-413----------------------S...RFERWS-PL-GLVVHITPGNAPLLA--FCAVIEGLLAGNVNWLR-PSSSDQGLT
Q93CP6_PHOLU/52-446----------------------E...SYIKAF-PK-GKSIHLLAGNVPLSV--IMSILRAILTKNQCIIK-TSSTDPFTA
LUXC2_PHOLE/50-444----------------------E...CYVKAL-PK-GKSVHLLAGNVPLSG--VTSILRAILTKNECIIK-TSSADPFTA
LUXC_VIBFI/51-445----------------------D...CYVKAQ-PK-GVSVHLLAGNVPLSG--VTSILRAILTKNECIIK-TSSSDPFTA
Q4A539_9GAMM/49-442----------------------D...CYIKAL-PK-GKSVHLLAGNVPLSG--VTSILRAILTKNECIIK-TSSTDPFTA
LUXC_VIBHA/49-443----------------------E...CYVRAF-PK-GRTMHLLAGNVPLSG--VTSILRGILTRNQCIVR-MSASDPFTA
A8LEK2_FRASN/68-470----------------------TGRKSYIRAF-AP-RLI.HVLPGNSPGVA--VKSIAQGALVKAVNLFK-MSSSDPFTT
Q97GS8_CLOAB/45-446----------------------Y...GYEHRQ-PR-GIIFHNISGNAFVVI--PMSISMGLLSKNCNLVK-VSKDEPYFA
A6LV85_CLOB8/35-425----------------------D..NKFMKAQ-PR-GMVCHFMAGNVPTLP--IYYLVQAIICRNVNLCR-IPIGSIDIV
Q9KV99_VIBCH/423-818----------------------DISHSSQKAM-PR-GIVSHWLSGNVPLLG--MFALVQSILSKNANILK-VSASESQAL

PF00171

Q7CTQ3_AGRT5/29-491NT......APV.G.........SNALALVVRE.PV.GVVGCVLPWNFPLLML.AWKIGPALASGCSVIVK.PAEETTLTT
Q7CSM1_AGRT5/15-474QV......IPARA.........TGVSQLAIKV.PV.GPVAAFTPWNFPLNQI.VRKLSAALATGCSIIVK.APEETPASP
Q7D3N3_AGRT5/14-476RA......KSP.K.........PGSLSVILRQ.PM.GVAGIIVPWNSPVILS.VRSFAPALAAGCTVVVK.MPGQTAQVG
Q7CVT1_AGRT5/28-485ET......IPTHL.........KGSNLSVRMQ.PI.GVTVAITPWNFPSAMI.ARKAGAALAAGCTMIVK.PAPETPLSA
A9A1B_DANRE/49-507QH......VQL.P.........GGSFAYTRRE.PF.GVCVGIGAWNYPFQIA.AWKSAPAIACGNSMVFK.PSPLTPVTA
BETB_ECOLI/15-479SQ......IPL.R.........ETSFVYTRRE.PL.GVVAGIGAWNYPIQIA.LWKSAPALAAGNAMIFK.PSEVTPLTA
ALDA_ECOLI/18-475EI......IQSDR.........PGENILLFKR.AL.GVTTGILPWNFPFFLI.ARKMAPALLTGNTIVIK.PSEFTPNNA
ASTD_PSEAE/10-467KS......GPL.A..........DATAVLRHK.PH.GVVAVFGPYNFPGHLP.NGHIVPALLAGNCVVFK.PSELTPKVA
ALDH6_YEAST/34-496RT......INTGD..........GYMNFTTLE.PI.GVCGQIIPWNFPIMML.AWKIAPALAMGNVCILK.PAAVTPLNA
CROM_ENTDO/24-487QN......IPV.D.........GDFFSFTKHE.PV.GICGLIIPWNYPMLMM.TWKMAPALSCGNCIVVK.PAEQTPLTA
O66573_AQUAE/12-471ET......FPI.DAH....PNGKGKLGFYIRV.PV.GIVSAITPFNFPLNLS.MHKVAPALAAGNAVILK.PSERTPLTP
Q6BX25_DEBHA/48-514DI......IPS.A........LADSKILVMRQ.PI.GVCGILTPWNFPAAMI.TRKLGAAAATGCTTVIK.PASETPLSA
Q93HF8_STRAW/48-523EY....................AGRKLILHRQ.PD.GVVAFNPPQNAPLPS..AALCVLALMAGNAVVVRAPRSIALSTM
LADH_METJA/7-459EV......IPS.D..........DRLIFTRRE.PV.GIVGAITPFNFPLNLS.AHKIAPAIATGNVIVHH.PSSKAPLVC
Q739I7_BACC1/23-485HY......DKH............NFMSYAKYA.PA.GVTSLIIPWNLPFMQM.TWKASAALASGNTVVVK.PASYTPLSA
O33455_PSEPU/24-488TT......PPISFD.......GREYHTYTRRE.PI.GVVGAITPWNYPLALG.SWKIASALAAGCTMVLK.PTELTPLST
O86742_STRCO/16-473RG......AGE.Y........MEGLTSFVRRE.PI.GVCAQVAPWNYPMMMA.VWKFAPALAAGNTVVLK.PSDTTPAST
Q7W0D6_BORPE/10-472EK......LPM.T........RPGIEVDVTRE.PV.GVVGIIAPWNFPIAIP.AWKIAPALAYGNTVVFK.PADLVPGSA
O52642_9PSED/19-476TL......FPS.A........VPGRMNLCHRV.PV.GVVGVIAPWNFPLFLA.MRSVAPALALGNAVILK.PDLQSAVTG
Q7UJE5_RHOBA/56-500KVGLTGRPVWM...........WGVRSVVQRV.PL.GRVLILGTWNYPLLLP.GVQMAQALAAGNHVWLK.PAPGSEAVS
Q98LH9_RHILO/20-482TY......TNIGD..........GKTALISRE.AV.GVVALVTPWNFPALIL.SQKVPFALAAGCTVVLK.PSEFTPGSA
Q6ABP5_PROAC/22-479DYG....LLPE...........GNIRQLVTKR.PV.GPCLFITPWNFPLAMA.TRKIAPALAAGCTVVIR.PASATPLTT
Q6ALY1_DESPS/13-480PS......LFNVS.........NGYDTVQQMR.PL.GVFAGIVPWNFPAMIPHGWMAPICMVTGNTMVLK.AASYVPRTA
Q82GU8_STRAW/29-495QINEAGPFGRA...........AVMGALAVRQ.PV.GVVTCITSYNNPWANP.AGKIAPALAMGNTVVVK.PAPQDPLSV
Q6N3D4_RHOPA/38-498LN......TPS.D..........EHWNVSTRV.PI.GPVGVITPWNTPFMLS.TWKIAPALAAGCTVVHK.PAEWSPVTA
ALDA_STAAS/21-483TV......NDIDK..........DTMSIVRHE.PI.GVVGAVVAWNFPMLLA.AWKIAPAIAAGNTIVIQ.PSSSTPLSL
Q8A340_BACTN/495-936EM.............................K.PK.GTILVISPWNFPCAIP.VGGIVAGLAGGNTVILK.PATVAAPVA
Q6PW33_9RALS/11-473SV......IPVEA..........SFLNYLTRE.PV.GIVGQVVPWNFPLMFT.SWKMAPALAAGNCVVMK.PAELTPLSS
BETB_BACSU/11-476EI......ISSPI.........PDSESKIIRE.PI.GVCGQITPWNYPLLQA.SWKIAPALAAGNTIVMK.PSEITPLTT
P74275_SYNY3/509-973QG......VNL.D........IPGETNRYFYQ.PR.GIALVISPWNFPMAIA.VGMTVAALVTGNCTLLK.PAETSTVIA
O06837_PSEFL/29-498STLDLSLPLPP.D.........VRSRASTQRV.PV.GVVAAIIPWNFPLLMA.VWKIAPALACGNTVVLK.PAEETPLTA
Q8GPZ0_PSEAI/20-479ER......YPS.D.........AQVTRFVRRN.GQ.GVHLSIAPWNYPVGLL.PWLIVTPILGGNTVILK.HAAQTTLIG
Q7WPE0_BORBR/13-475ER.....................IGNGLVERV.PV.GVIAAITPWNFPLHQI.VAKVAAALAAGCTVVLK.PSELAPGAA
Q6AA40_PROAC/499-947D.......GAQFV....................PP.RVTVVTPPWNFALSIT.AGSTLAALAAGSSVLLK.PAPQARHCA
P96405_MYCTU/17-478TE......TRTGS..........YGQSIVSRE.PV.GVVGAIVAWNVPLFLA.VNKIAPALLAGCTIVLK.PAAETPLTA
Q8ELI8_OCEIH/14-471ET......IPG.SSS....ERGLNTIASIYRV.PV.GVVAAITPFNAPLNLV.CHKVGPAFAGGNVTLLK.PAPQTTLIA
Q9RZE6_DEIRA/24-482ER......INLRF.........PHKRGLTISE.PV.GIVYAVTPWNFPAGMI.TRKAAPALAAGCVMILK.PAELSPMTA
AL1L1_HUMAN/430-898ST......IPINQA......RPNRNLTLTRKE.PV.GVCGIIIPWNYPLMML.SWKTAACLAAGNTVVIK.PAQVTPLTA
ALDH5_BACSU/16-474KI......LPS.T........IDGKENRLYRV.PA.GVVGVISPFNFPFFLS.MKSVAPALGAGNGVVLK.PHEETPICG
Q97UA1_SULSO/11-474KT......LPS.A........DPNTRIFTVKE.PL.GVVALITPWNFPLSIP.VWKLAPALAAGNTAVIK.PATKTPLMV
Q92XQ0_RHIME/15-479TL......HPC.D........K.PALSFSRHE.PL.GVCVGIVPWNAPLLLF.SLKAAPALAAGNTLVMK.PAEFTSATA
O24897_HELPY/516-965NT......KTQFT....................PK.GVGVVIAPWNFPVGIS.VGTIAAPLATGNRVIYK.PSSLSSVTG
Q18822_CAEEL/36-498TI......LEQPT.........GKFVNYVKND.PV.GVAGLISPWNLPLYLL.SFKLAPALVAGNTVVCK.PSEMTSVTA
O49218_ORYSA/49-511EY......VSNVS.........NGIDTFSIRE.PL.GVCAGICPFNFPAMIP.LWMFPIAVTCGNTFVLK.PSEKDPGAA
Q8KVX3_9RHOB/30-494SL......TATDP..........SVVHYILRQ.PL.GVVGLITPWNYPLMMA.AWKLGPALITGNSVVLK.PAEQAPLSC
Q20352_CAEEL/214-676QH......VPLDA..........SRYAYTRRL.PV.GVVAAIGAWNYPIQTC.SWKTAPALACGNAVIYK.PSPLSPVTA
Q88PZ0_PSEPK/11-471KNRT..VPLAA.P..........GFTARTRLE.PV.GVVGLIVPWNFPLVTS.AWKLAPALAAGCTVVLK.PSEVTPLIE
Q881E4_PSESM/24-482VI......LPS.A.........AGRLSYARRV.AH.GVVGVISPFNFPLVLS.LRSVAPALAAGNAVVLK.PDPQTPISG
Q6HJ76_BACHK/11-470ET......LPL.DAA....PGADGRIAYTIRK.PI.GVIGAITPFNFPLNLV.AHKVGPAIAAGNTVVLK.PADQTPLSS
Q95TY8_DROME/95-558RF......EIQGD.........MNVFPSFHLR.PMDGFVAALAPFESVALSS.SLALCPALM.GNTVLWN.PSLEVAPVS
Q8ZV31_PYRAE/12-467KT......LQSDA.........EGVVSMVFKR.PK.GVVGVITPWNYPLSIS.MKKIAHALATGNTIVYK.PASETPVTG
Q6MQ98_BDEBA/11-457QV......LPQ......................PV.GLVGIIASWNLSLLLV.IERLAPALAAGNACVVK.ISELSPITA
Q9AH09_RHOER/16-479RT......TPAPG..........RFLNYTLRE.PI.GVVGAITPWNFPAVQA.VWKIAPALAMGNAIVLK.PAQLAPLVP
Q6F9F7_ACIAD/12-472SF......IPVDK.........PDMQAWLVRE.PV.GVVAAIVPWNSQLFLS.AVKVGPALAAGCTVVLK.ASEEAPAPL
Q70Q17_RICRI/17-471TI......KPGNS.........NTHKIVTQFE.PV.GPSAAITPWNFPNAMI.ARKVVPAIAAGCSVILK.PSSLTPLSA
Q92UV7_RHIME/21-480EI......FSC.DLT....PHGKARKIFTMRE.PL.TAISAITPFNHPLNMV.AHKVAPAIATNNCVVVK.PTELTPMTA
Y4UC_RHISN/49-507EI......VPF.DAY....TGSEQRQGWFTRD.PL.GIITAITPYNDPLNLV.AHKLGPAIAGGNAVMLK.PSNLTPFSA
Q6MMT9_BDEBA/20-477GK......M.EVS.........RGVSCEFRRE.PL.GVIANITPFNFPAMVP.MWTIPIALTLGNAYIWK.PSEKTPLTS
Q703Z2_THETE/51-524YV......LQMRSP.......IPNERPLSVLR.PY.GAWFVISPFNFPIALA.KGMLTGVLLMGNTAVWK.PTSEAPFTA
Q73Y73_MYCPA/6-480ES......ANLVSDGL..LGTWETYHTFTQLE.PV.GVVGLIIPWNGPFFVA.MLKVAPALAAGCSAVLK.PAEETPLTA
Q8FS05_COREF/26-487RRQ...GTIPVLS.............STVEHRYPL.GVIGQISPWNYPLTLA.ISDAIPALLAGNAVVSK.PDERTPFTA
Q93P88_9BACT/17-480DI......IPSDN.........PAEHIMIHKI.PR.GVVVAITAWNFPLALA.GRKLGPALVAGNSVVLK.PTQETPIAT
YF19_SCHPO/31-493QT......IETDI..........KRFAYTRHE.PI.GVCGQIIPWNFPFLMC.AWKIAPAVACGNTIILK.TAELTPLSA
Q8FS49_COREF/31-498DI......RPFPA.........GGAESLVDKD.PI.GVCALIAPWNFPINLV.VIKLAPALLAGCSVVIK.PASPTPLSI
O34184_HALVO/20-485EH......VAS.N........IPGKENIVQKN.PK.GVVTVISPWNFPLNLS.MRAVAPAVAAGNAVVLK.PSTNSPITG
ALDHX_YEASX/49-508RF......LRKSK........DENVMEAATR.....GIITIRQLYY.......ENKVLPLRFTGNVATH..IEENLEFEE
Q9KC36_BACHD/16-473ET......IPF.SQM....PGHERRVGYFYRF.PI.GIIVAITPFNDPLNLV.AHKIGPAIAAGNSLIIK.PSSFTPLSA
Q721Q0_LISMF/21-482ET......IPA...........PNNHAFIVKKQPI.GVVAAITPWNFPGGMV.TRKLAPALATGNTIVLK.PSGDTPLSA
Q6FDG9_ACIAD/11-475EL......TSQ.R........APDFMTFSVHE.PV.GVVAAITPWNSPIASE.VQKLAPALAGGNAVILK.PAEATSLIA
PUUC_ECOLI/28-489EV......ATTSS..........HELAMIVRE.PV.GVIAAIVPWNFPLLLT.CWKLGPALAAGNSVILK.PSEKSPLSA
ABDH_ECOLI/11-470........LAAGEY.......LEGHTSMIRRD.PL.GVVASIAPWNYPLMMA.AWKLAPALAAGNCVVLK.PSEITPLTA
BADH_AMAHP/16-485KQKA.PIALPM.D..........TFKCHVLKQ.PI.GVVGLISPWNYPLLMA.TWKVAPALAAGCSAVLK.PSELASVTC
O24829_ACISP/12-482........VPT.ESFEMPTPDGTGALNYAVRR.PK.GVIGVISPWNLPLLLM.TWKVGPALACANTVVVK.PSEETPTTT
Q7UFE0_RHOBA/24-485ET......VPIRG..........NYLCYTRKE.PV.GVVGQIIPWNFPMLMV.AWKWGPALATGCTIVMK.PAEQTPLTC
P83849_THETH/46-512PA......VEVVP........YPGEDNESFYV.PL.GAGVVIAPWNFPVAIF.TGMIVGPVAVGNTVIAK.PAEDAVVVG
Q73RK8_TREDE/20-482KV......VPS.E.........YGTLNYVTWN.PC.GVVGEILPWNGPFLMG.CQKVNAILAAGNTVVIK.PPSWGVLSM
Q6L285_PICTO/9-471DI......VEG.T........SNKRKIFQYKV.PY.GIVIAITPWNFPAAMV.IRKLAPALLTGNTVILK.PSSDTPLTA
Q82K12_STRAW/25-486QS......AGE.Y........SGDHTSYIRRE.PI.GVVGSIAPWNYPLQMA.AWKVLPAIAAGNTIVLK.PAEITPLTS
Q6G1A0_BARQU/13-473QD......VLVEG..........NEQSILHYD.PI.GVVGLITPWNWPMNQV.TLKVIPALLAGCTMVLK.PSEIAPLSA
Q7S5U4_NEUCR/22-482QS.......SV.N........TPGYVTMTFRQ.PF.GVAACIIPWNAPLYFF.ATKAAAALITGNTVVLK.SSEKAPLAV
Q88LI4_PSEPK/30-488ET......INLGP..........SYHAYTTRE.PF.GVVGVILPWNSPLNQA.GRAIAPALVSGNTVVVK.PSEFTSVTM
O85031_9RALS/11-472ET......IPTDK.........PDTLSMTLRH.AV.GPILSIVPWNGTAVLA.ARAIAYPLVCGNTVVFK.GSEFSPGTH
ALDH1_BACSU/18-484DV......IPS.T........DKDALMFTTRV.PL.GVVGVISPWNFPVAIP.IWKMAPALVYGNTVVIK.PATETAVTC
Q7UYE1_RHOBA/30-491TK......LDV...........PGHDAYTVKQ.PW.GACAFIFPWNFPFLLI.GWGISPALAAGNTVVIK.PAEDTSLSA
Q74E56_GEOSL/13-471EI......VPM.DAS....PVSAGRFGFYLRT.PI.GVIGAIAPFNFPLNLV.AHKVAPAIAAGNAIVLK.PATKTPLSS
O85973_SPHAR/26-487QT......LDY...........PDAIGIVHRE.PL.GVCAQIIPWNVPMLMM.ACKIAPALASGNTVVLK.PAETVCLSV
Q7WBK1_BORPA/13-471YT......YASIR.........PGVRVEVQRN.PV.GVVALVTPWNFPVVIP.AWKAAAALAYGNTVVMK.PSEIAPCGA
Q6FBY4_ACIAD/20-482SA......GEL.SN......VAGSFHAYSRRQ.PV.GVVAAITPWNFPSVLS.MWKIAPALAAGCCIVLK.PASDTPLTA
Q8FY44_BRUSU/28-490ES......YNTLG.........DGTLGVVLRE.AI.GVVSIITPWNFPFLIV.GQKLPFALAAGCTAVVK.PSELTSGST
IOLA_BACSU/15-477DS......LASIA.........TDVEAANYRY.PI.GVVGGIAPFNFPMMVP.CWMFPMAIALGNTFILK.PSERTPLLT
Q6SF25_9BACT/16-478RS......IPLGA..........GYFDFTTDE.PY.GVSAQIIPWNFPVEMT.ARSLSAALTTGNTVVVK.PPEMTPLSN
Q6BPC7_DEBHA/15-474.V......IPKSN.........YCDLALTFRQ.PV.GTILSISPWNAPVILG.TRSIVGPLAAGCSVIVK.SSEKAPHSA
Q828R7_STRAW/13-460ER.....................VGNSTVHHE.PV.GVVGAITPWNYPLHQI.VAKVAPALAAGCTIVLK.PAEDTPLTA
Q7NEN1_GLOVI/15-481QT......TPS.E........MDNKFAMSVRS.PV.GVCSLITPWNFPVAIP.CWKALPALVCGNTVILK.PAEDTPACA
ALDY_BACSU/15-474KE......VPS.D........IEGKTNKIYRL.PL.GVISSISPFNFPMNLS.MRSIAPAIALGNSVVHK.PDIQTAISG
Q47943_GLUOY/25-486DT......FNN.L........GEGLFGMVLRE.PI.GVVGLITPWNFPFMIL.CERAPFILASGCTLVVK.PAEVTSATT
Q75TI0_GEOSE/8-466EE......IKR.T.........DGTTSKIIEE.PI.GVCALIVPWNFPLLLG.IWKLAPALAAGNTVVFK.PSELTPLSF
Q8TWC7_METKA/11-466ET......LPG.DAQ....RGRTAELILTVRE.PV.GVVLSITPYNFPLLLP.THKLGPALAARCSVVHK.PATVTPLSS
Q59095_ACICA/18-473TL......LPT.Q.........NGKLSIAKRL.PL.GVVGVISPFNFPLYLA.LRAVAPALAFGNAVVLK.PDERTAVCS
ROCA_BACSU/45-511EG......APVKS........RAGEVNQYHYE.AL.GVGIVISPFNFPLAIM.AGTAVAAIVTGNTILLK.PADAAPVVA
Q7WPN3_BORBR/33-490DV......IPVPN..........QYLNYTMRE.PI.GVLLHIVPWNSPLFMA.AWHLAPSLATGNAVLLK.PSELTPLSA
ALD1_STAAS/13-470E...........E........R.RGDDLVVKE.AI.GVSGLITPWNFPTNQT.SLKLAAAFAAGSPVVLK.PSEETPFAA
O50203_XANAU/26-493GI......SEI.D........H.DTVAYHFHE.PL.GVVGQIIPWNFPILMA.VWKLAPALAAGNCVVLK.PAEQTPASI
Q6W1I3_RHISN/34-497RT......VEP.SL......PG.NYLAYTRKE.PL.GVVAAIVPWNFPLQTL.AWKLAAALAVGCTAIVK.PAELTSLST
Q7VSP3_BORPE/17-482ET......FVNDD.........PDMVVYSQRE.PL.GVVTVISPWNFPVSIP.ARKIAPALITGNTVVFK.PSSDAPLSG
Q9L124_STRCO/18-473EV......LTS.E.........DARWSLARRR.PA.GVVSVIAPFNFPLILG.LRSVAPALALGNSVLLK.PDPRTAVSG
Q6JHN1_9PSEU/12-470HS......LPPNG..........DFVAYTRHV.PF.GVTGHIIPWNYPLQIG.CRTIAPAIAVGNCAVVK.PAEEAPLSV
BADH_SCHPO/29-495DNPTVKVPLPNNP..........GFCAFEKRF.PR.GVIGVITPWNFPLKMA.LWKLVPAIASGNCVVLK.PSELAPWSC
Q59702_PSEPU/20-480RI......LAS.D........VPGKESRVYRE.PL.GVIGIISPWNFPLHLT.ARSLAPALALGNACVIK.PASDTPVTG
MSC7_YEAST/104-587SR......RPGPTNF....FMKWYKGAEIRYE.PL.GVISSIVSWNYPFHNL.LGPIIAALFTGNAIVVK.CSEQVVWSS
Q73WS7_MYCPA/19-482EV......AGI............SAGTTLLRHVPL.GVVAVLTPWNFPHCLN.VMKLNHALAAGNTVVLK.PSPLTPLAG
GAPN_PEA/24-484GKFLVSDSFPGNE.........RTKYCLTSKI.PL.GVILAIPPFNYPVNLA.VSKIAPALIAGNSIVLK.PPTQGAVAA
Q6MF92_PARUW/536-989DV.............................KWSAKGVVVIAPPWNFPCSIA.AGGILAALVTGNTVILK.PAFESVLVC
Q8CN25_STAES/16-475RV......LQNSI.........ANETIQIINK.PI.GVTAGIVPWNAPILVL.MRKVIPAIVTGCSVVIK.PSEETTLLT
O87842_STRCO/48-500RA...............................PLDGPVSNIASWNYPMSVL.VHALLVQALAGNAVIAKTPTDGGVACL
AL7A1_DICDI/28-492QV......MPSER.........PNHILMETWN.PL.GLVGIITAFNFPCAVL.GWNAAISMICGNVQLWK.GASTTSLIT
Q6CRD2_KLULA/26-495QS......FAP.S........S.EKLAYTLHQ.PL.GVVGCIIPFNYPLAMM.SWKWT.AIATGNTTVFK.SADQTPLSI
Q885F4_PSESM/28-486EV......IPVPT..........THLNYVTYE.PL.GTVLQITPWNAPIFTC.GWQIAPAIAAGNAVILK.PSELTPLSS
Q6AKR4_DESPS/50-520AT......MPSER.........PSHRLYDQYH.PL.GVVGIITAFNFPAAVW.AWNAMLSTVCGNVLVWK.PSSQVGLTA

PF07368

Q9VAW6_DROME/82-298---------------------------------PC---------------------------------------------
Q9VYG8_DROME/38-250---------------------------------PQ---------------------------------------------
Q9W2S6_DROME/22-243---------------------------------PT---------------------------------------------
Q8T485_DROME/35-252---------------------------------AR---------------------------------------------
Q9W1T5_DROME/37-260---------------------------------PR---------------------------------------------
Q9V9P6_DROME/64-279---------------------------------PQ---------------------------------------------
Q9VI33_DROME/97-311---------------------------------PR---------------------------------------------

PF00815

HISX_ECOLI/17-428ET-------------------QPGVRCQQVTR-PVASVGLYIPGGSAPLFSTVLMLATPASIAGCKKVVL-CSPPP.I..
HISX_BACSU/10-423KD-------------------..GTMLGQKVT-ALDSAGVYVPGGTAAYPSSVLMNVIPALVAGVERIVL-VTPPG.K.D
HISX_ARCFU/2-402EF-------------------E.DCVMGKIYT-PIEKVGAYIPGGRASYPSTALMIGVPAKIAGVEKLVA-CTPPN.K.D
HIS2_NEUCR/445-864ET-------------------MPGVVCSRFSR-PIEAVGCYIPGGTAVLPSTALMLGVPAMVAGCNKIVF-ASPPR.A.D
HISX_METTH/13-425VR-------------------P.GVMAGQLVR-PIDSVGCYIPGGRAVYPSTILMTVIPARIAGVERIVC-CTPPA.Q.D
HIS2_PICPA/422-837ET-------------------CPGVVCSRFAR-PIEKVGLYIPGGTAILPSTSLMLGVPAKVAGCKEIVF-ASPPK.K.D
HISX_HAEIN/14-423EI-------------------QEGVRCQVVTR-PISCVGLYIPGGSAPLFSTVLMLAIPAKIAGCKKIVL-CSPPP.I..
HISX1_SYNY3/15-432EI-------------------EPGVFAGEKIT-PLPTVGLYVPRGKGAFPSMMLMLAVPARVAGVKKIVV-CTPPD.K.E
HISX_STRCO/18-434QV-------------------VPGGSVTEKWV-PVERVGLYVPGGRSVYPSSVVMNVVPAQEAGVGSIAL-ASPAQAEFG
HISX_BRAOC/46-459EN-------------------MKGVRCKRVSR-SIGSVGLYVPGGTAVLPSTALMLAIPAQIAGCKTVVL-ATPPT.K.E
HISX_BUCAP/18-429ET-------------------QVGVRCQQIYL-PLNSVGIYIPSGIAPLFSTVLMLAIPAKIAGCKQIIL-CSPPP.I..
HIS2_KLULA/366-785ET-------------------QPGVVCSRFPR-PIEKVGLYIPGGTAILPSTALMLGVPAQVAGCKEIVF-ASPPR.KSD
HISX_MYCSM/24-444TL-------------------APGATVTERWV-PVERVGLYVPGGNAVYPSSVVMNVVPAQTAGVDSMVI-ASPPQGQFG
HISX_AQUAE/18-425EE-------------------E.GIILGQKVV-PLEKVGVYVPGGKAAYPSTVLMNVVPASVAGVEEIIM-VSP......
HIS2_CANAX/412-832ET-------------------SPGVYCSRFAK-PIENVGLYVPGGTAVLPSTAMMLGVPAKVAGCKNIIV-ASPPS.RAT
HISX_METJA/18-429EN-------------------N.GIILGQVVR-AIEKVGCYVPGGRAFYPSTVLMTTIPAKVAGCEEIYI-TSPPT.K.D

PF05893

Q8G6W7_BIFLO/65-480-AFFARSIAM-V----NSD...........LADAIAVVPW.KGG-SQQLEDSAI-.--------.DAADAVIVYGSSQTT
Q7MZU4_PHOLL/30-413-AQILAEFLR-H----DLSG.........TLAPYISVL...PLP-SDQLSELL.-.--------.ACADAVSAWGSNSAL
Q7NQ23_CHRVO/30-413-SRLLAELLR-H----DASG.........RLAARVAVL...PAP-SDALPRLM.-.--------.ADADGVSAWGGDAAL
Q3KD56_PSEPF/30-413-AQLLHGLAQ-C----DATG.........QIAGHIAVV...PAS-TAQVGQLC.-.--------.QRANGVSAWGGESAL
Q93CP6_PHOLU/52-446-NALALSFID-V----DPNH.........PITRSLSVVYWPHQG-DTSLAKEIM-.--------.QHMDVIVAWGGEDAI
LUXC2_PHOLE/50-444-TALVNSFID-V----DAEH.........PITRSISVMYWSHSE-DLAIPKQIM-.--------.SCADVVIAWGGDDAI
LUXC_VIBFI/51-445-NALVSSFID-V----NADH.........PITKSMSVMYWPHDE-DMTLSQRIM-.--------.NHADVVIAWGGDEAI
Q4A539_9GAMM/49-442-TALVSSFID-V----NADH.........PITRSMSVMYWSHNE-DMSLPKKIM-.--------.NHADVV.AWGGDEAI
LUXC_VIBHA/49-443-HALAMSFID-V----DPNH.........PISRSISVLYWPHAS-DTTLAEELL-.--------.SHMDAVVAWGGRDAI
A8LEK2_FRASN/68-470-VAVLRTMAD-I----DPGH.........PIVRSMSAVYW.RGG-DNTVEQVLY-R--------PQYFDKIVAWGGGDAI
Q97GS8_CLOAB/45-446-YAFYKSLCE-L----DE...........TVKDRLSVLYF.DSS-KTEIYDTIV-.--------.KNSDGVIHWGGEYSS
A6LV85_CLOB8/35-425-IELLKPLKD-I----VINF.RGEKYYGSTLLKSISIINF.SSN-DLKLNTEIS-.--------.QVADVRVICGGEEAV
Q9KV99_VIBCH/423-818-PVLLATFKG-L----SYTTPGGYTIHGDDLLGTLAVVYF.DRH-QTKIAEKFS-.--------.ANADVRIAWGGREAI

PF00171

Q7CTQ3_AGRT5/29-491.LRVAELAHE.A....GIPA------------GVFNVV...PGG.GKEVGEPIG.M--------HMDVDMVAFTGSTPTG
Q7CSM1_AGRT5/15-474.AELIRAFVD.A....GVPA------------GVIGLV...YGV.PSEISEYLI.P--------HPVIRKISFTGSTPIG
Q7D3N3_AGRT5/14-476.SVITEVLAE.A...TDLPE------------GVVNMF...VES.GADGAALLV.E--------SPDVPTISFTGSTQTG
Q7CVT1_AGRT5/28-485.LALARLAEE.S....GVPP------------GVLQVL...PGE.AAPLARRLL.E--------NTEVRAFSFTGSTEVG
A9A1B_DANRE/49-507.VLLAEIYRQ.A....GAPE------------GLFNVV...QG..GQETGSLLC.L--------HPSVEKVSFTGSVPTG
BETB_ECOLI/15-479.LKLAEIYSE.A....GLPD------------GVFNVL...PGV.GAETGQYLT.E--------HPGIAKVSFTGGVASG
ALDA_ECOLI/18-475.IAFAKIVDE.I....GLPR------------GVFNLV...LGR.GETVGQELA.G--------NPKVAMVSMTGSVSAG
ASTD_PSEAE/10-467.ELTLKAWIQ.A....GLPA------------GVLNLV...QG..GRETGVALA.A--------HRGLDGLFFTGSSRTG
ALDH6_YEAST/34-496.LYFASLCKK.V....GIPA------------GVVNIV...PGP.GRTVGAALT.N--------DPRIRKLAFTGSTEVG
CROM_ENTDO/24-487.LYCASLMEE.A....GFPP------------GVVNVV...PGY.GTICGQSIS.S--------HLDINKVSFTGSTEVG
O66573_AQUAE/12-471.LMLGEILLE.A....GVPP------------KALSVI...PGY.GD.VGKAMT.T--------HPDVRVVSFTGSRKVG
Q6BX25_DEBHA/48-514.LALAYLAEQ.A....GFPK------------GSVNVL...PSSDAAGVGKLMC.E--------NPTIKKVSFTGSTNVG
Q93HF8_STRAW/48-523.WLLRDIVAP.ILEEFDAPP------------GVLNAV...CSN.PKQTMDRWI.A--------DPLINDIFYIGGSQEG
LADH_METJA/7-459.IELAKIIEN.ALKKYNVPL------------GVYNLL...TGA.GEVVGDEIV.V--------NEKVNMISFTGSSKVG
Q739I7_BACC1/23-485.VMLGEIAND.A....GLPP------------GVLNII...TGP.GSTVGTKMT.T--------HPAVRRISFVGESNTG
O33455_PSEPU/24-488.LRLAELCLE.A....GLPE------------GALNIV...NGH.GHEAGEALA.R--------HPGVDKITFTGSTVVG
O86742_STRCO/16-473.ALMADIIGS.I.....VPK------------GVFNVV...CG..DRDTGRLMV.E--------HETPAMASITGSVRAG
Q7W0D6_BORPE/10-472.WALAEILSR.A....GLPA------------GVFNLV...MGR.GSVVGQAIL.D--------DRRVNAISFTGSVATG
O52642_9PSED/19-476GALIAEIFSD.A....GMPE------------GVLHVL...PGG.V.DVGESMV.A--------NSGINMISFTGSTQVG
Q7UJE5_RHOBA/56-500AELVAAFVAA......GVPE------------SAVTSL.......GSSTEAAIEAQ--------SKGVGLVVLTGSAQTG
Q98LH9_RHILO/20-482.FEIAALAAE.A....GVPA------------GAFNVV...SGY.GATAGDHLT.G--------HMGIDFVSFTGSTRTG
Q6ABP5_PROAC/22-479.LLLAKTFLE.A....GLPA------------GVLNVI...TGL.DHAVTDAIL.E--------DPRLRKLSFTGSTGVG
Q6ALY1_DESPS/13-480.MRLMELWQE.A....GLPP------------GVLNLV...TA..NRTEAEILL.R--------HPEIKGVSFVGSTTVG
Q82GU8_STRAW/29-495.YRMAEALQA.A....GVPP------------GVVNVV...SGS.GAQAGEAAV.D--------CPDVDMVSFTGSTAVG
Q6N3D4_RHOPA/38-498.DMLARICKD.A....GLPD------------GVLNTV...HGF.GEEAGKALT.E--------HPAIKAIAFVGETATG
ALDA_STAAS/21-483.LEVAKIFQE......VLPK------------GVVNIL...TGK.GSESGNAIF.N--------HDGVDKLSFTGSTDVG
Q8A340_BACTN/495-936.WMFAKAFWD.A....GVPK------------EALQVI...IT..RREALKVLT.T--------APAIKHIILTGGTDTA
Q6PW33_9RALS/11-473.LAIAQLMAE.V....GFPA------------GVVNVL...PGF.GHVAGQYIA.E--------HPEIGKVAFTGSTAVG
BETB_BACSU/11-476.IKVFKLMEE.A....GVPK------------GVANLV...LGP.GATVGDELA.V--------NKDVDLISFTGGIETG
P74275_SYNY3/509-973.AKIAEILIA.A....GVPP------------GVFQYV...PGK.GSVVGSHMV.N--------HPDVHLIAFTGSREVG
O06837_PSEFL/29-498.LRLAELAME.A....GLPA------------GALNVV...TGR.GETAGDALV.R--------HPKVAKVAFTGSTEVG
Q8GPZ0_PSEAI/20-479.RIVKEAYEA.I....GGPA------------GVLQVL.....ELGHDQVTTAI.K--------SGVVKGVNFIGSVGGG
Q7WPE0_BORBR/13-475.WQFIQACHD.A....ALPP------------GVVNLV...WGD.AAI.GQALV.A--------HEAVDQVSFTGSTEVG
Q6AA40_PROAC/499-947.AVISECLWE.A....GIPR------------DVLQLV...DVE.ENEAGKHLV.S--------HPEVDRVILTGAWETA
P96405_MYCTU/17-478.NALAEVFAE.V....GLPE------------GVLSVV...PG..GIETGQALT.S--------NPDIDMFTFTGSSAVG
Q8ELI8_OCEIH/14-471.TAFLQLLFE.A....GFPK------------NAIHML...LG..GVDVGQQIV.K--------DERINVISFTGGLVAS
Q9RZE6_DEIRA/24-482.LYLTELWLK.A....GGPA------------NTFQVL...PTNDASALTQPFM.N--------DSRVRKLTFTGSTEVG
AL1L1_HUMAN/430-898.LKFAELTLK.A....GIPK------------GVVNVL...PGS.GSLVGQRLS.D--------HPDVRKIGFTGSTEVG
ALDH5_BACSU/16-474GTLIAKIFEN.A....GIPA------------GLLNVV...VTD.IAEIGDSFV.E--------HPVPRIISFTGSTKVG
Q97UA1_SULSO/11-474.AKLVEVLSK.A....GLPE------------GVVNLV...VGK.GSEVGDTIV.S--------DDNIAAVSFTGSTEVG
Q92XQ0_RHIME/15-479.LKLMELVEK.A....GFPT------------GVINVV...TGY.GPEVGEPLV.T--------HPLTRHVGFTGSTKTG
O24897_HELPY/516-965.YKLCECFWD.A....GVPR------------DALIYL...PSK.GSDISEHLL.R--------DESIQFAILTGGEDTA
Q18822_CAEEL/36-498.WVLMHAFKL.V....GFPP------------GVVNMV...IGE.GKSAGQRLV.D--------HVDVPLISFTGSTVIG
O49218_ORYSA/49-511.MMLAELAME.A....GLPK------------GVLNIV...HG..THDVVNNIC.D--------DEDIQAVSFVGSNIAG
Q8KVX3_9RHOB/30-494.ALLGDLFLK.A....GGPA------------GVLNVV...QGL.GEEAGKAIG.L--------HPDVDKIGFTGSTEVG
Q20352_CAEEL/214-676.LILAEILKS.A....GLPD------------GVFNVI...QG..DAETAQDLI.H--------HDGVSKVSFTGSIPTG
Q88PZ0_PSEPK/11-471.QAYGQIADA.L....GLPA------------GVLNIV...NG..KAETGAALS.N--------HNGLDKLSFTGSNSVG
Q881E4_PSESM/24-482GFLIARLFEE.A....GLPK------------GLLHVL...PGA.A.DAGEALC.R--------DTNVQMITFTGSTGAG
Q6HJ76_BACHK/11-470.YALIELFEE.A....GLPK------------GALNII...SGP.GSTVGEAIV.T--------NDDVASITFTGSPKVG
Q95TY8_DROME/95-558.YLIFRAFQE.A....GLPS------------GVINFV...PAN.ERLFLDTIT.D--------AVHFAGLNTQASAAFY
Q8ZV31_PYRAE/12-467.FKIAEMIHQ.A....GFPK------------GVFNLV...VGP.GSTVGDEIV.V--------NKKVSHVTFTGESATG
Q6MQ98_BDEBA/11-457.QILGEALQK.A....EVPA------------GAVSLL...QG..DAEVGKVVA.G--------HPSIHAVTAVGKTSTM
Q9AH09_RHOER/16-479.VALGELALE.A....GLPP------------GLVNVL...PGR.GSVAGNALV.Q--------HPSVGKVTFTGSTEVG
Q6F9F7_ACIAD/12-472.LEFAKLIDE.A....GFPA------------GVVNVI...TGF.GPECGAVLS.A--------HPKVAHIAFTGGPETA
Q70Q17_RICRI/17-471.LVLAKFASD.A....GLPS------------GVFNVI...TGS.SDIIGKAFC.E--------DFRLRKLSFTGATNVG
Q92UV7_RHIME/21-480.LLLADILYE.A....GLPP------------EMLSVV...TGW.PADIGMEMI.T--------NPHVDLVTFTGSVPVG
Y4UC_RHISN/49-507.IKLVGALRE.A....GLPE------------EVITIS...HGD.RELVTAMIA.A--------.REVRMVSFTGGFATG
Q6MMT9_BDEBA/20-477.MKIAAALQE.A....GLPD------------GLFQVL...HG..GKDTVEAII.D--------HPQVKAVGFVGSTKVA
Q703Z2_THETE/51-524.ALVYQLAVE.A....GVPP------------GVLNFV...TGP.GDAVEEVAT.G--------DPRVAGIAFTGSRDVG
Q73Y73_MYCPA/6-480.LKLEEIFRE.A....GLPD------------GVLNVI...TGY.GETTGAALT.A--------HPDVDKISFTGSTEVG
Q8FS05_COREF/26-487.LLVTSLLYD.A....GLPR------------DIFHTV...TGP.GPVVGGAIA.E--------H..CDYLMFTGSTNTG
Q93P88_9BACT/17-480.LELGNIANK.V....GLPK------------GLINIL...TGQ.GSVLGNALV.A--------NPITKMVSMTGSTPAG
YF19_SCHPO/31-493.LCLTKFVPE.C....GFPP------------GVINVL...SGD.GRRCGNAIS.S--------HMDIDKVAFTGSTGVG
Q8FS49_COREF/31-498.RFIIEAVEA.A....GVPA------------GVINLL...TGS.GR.FGDAMV.R--------HPGVNKVAFTGSTPVG
O34184_HALVO/20-485GLLFAKLFEE.T....DLPE------------GVVNVV...TGR.GSEIGDRVA.G--------HPESDVVAFTGSTEVG
ALDHX_YEASX/49-508.QITWRTHVDSS....IFPN------------TRCAYP...SGY.GPSAKIPCL.S--------HKPNDILAYTGSTLVG
Q9KC36_BACHD/16-473.LRLVKALEE.A....GLPK------------KIVQVI...TGH.GSVIGPTLT.K--------HRDVRLISFTGGYETG
Q721Q0_LISMF/21-482.LAIFEIFEE.A....GLPK------------GVANIV...MGS.SKEIGETLT.D--------SDDVRKLTFTGSTKVG
Q6FDG9_ACIAD/11-475.LELAKIFEE.A....GLPK------------GLLSVL...VGK.GSVVGDAIV.K--------HPLVRKISFTGGTTTG
PUUC_ECOLI/28-489.IRLAGLAKE.A....GLPD------------GVLNVV...TGF.GHEAGQALS.R--------HNDIDAIAFTGSTRTG
ABDH_ECOLI/11-470.LKLAELAKD......IFPA------------GVINIL...FGR.GKTVGDPLT.G--------HPKVRMVSLTGSIATG
BADH_AMAHP/16-485.LELAEVCRE.V....GLPP------------GVLNIL...TGL.GPEAGGPLA.C--------HPDVDKVAFTGSTATG
O24829_ACISP/12-482.ALLGEVMKE.A....GIPT------------GVYNVV...HGFGGDSAGAFLT.E--------HPQVDGFTFTGETVPG
Q7UFE0_RHOBA/24-485.LRMAQLAKE.V....GFPD------------GVINVV...PGF.GPTAGGALV.D--------HPGVDKIAFTGEHRTA
P83849_THETH/46-512.AKVFEIFHE.A....GFPP------------GVVNFL...PGV.GEEVGAYLV.E--------HPRIRFINFTGSLEVG
Q73RK8_TREDE/20-482.ILMASIYEE.A....GFPS------------GVVNVV...TGS.GAEVGNCLV.E--------SELVDMVSMTGGVETG
Q6L285_PICTO/9-471.EWLVKKFVD.A....GIPK------------GVLNLI...TGK.GSEIGDYIV.E--------HKKVSLITMTGSTSTG
Q82K12_STRAW/25-486.LLFAEAATR.A....GIPD------------GVVNIV...TGA.GRDAGEHLV.A--------HPDVAMTSFTGSTAVG
Q6G1A0_BARQU/13-473.MLFAEILDE.A....ALPA------------GVFNLI...NGD.GDNIGSYLT.A--------HPDLEMISFTGSTRAG
Q7S5U4_NEUCR/22-482.AYAAELVAK.A....GFPP------------GVFNIL...SGH.GLPSGRCLA.R--------HMDVRAISFTGSSRTG
Q88LI4_PSEPK/30-488.LQFAELVVKEA....GLPP------------GVLNVV...TGT.GKETGEPLV.K--------HPLIRKVAFTGSVRAG
O85031_9RALS/11-472.ALITKCLQE.A....DLPA------------GVLNYLNSSPDR.SPDIADALI.S--------SKEIRRINFTGSTRVG
ALDH1_BACSU/18-484.AKIIACFEE.A....GLPA------------GVINLV...TGP.GSVVGQGLA.E--------HDGVNAVTFTGSNQVG
Q7UYE1_RHOBA/30-491.IYLAQLAKE.V....GVPD------------GVINVV...TGR.GATAGAALT.N--------NAEIKRMSFTGSPEVG
Q74E56_GEOSL/13-471.IKLAELMVE.A....GLPA------------GALNLV...IGS.GRTVGNRLV.E--------DDRLAMVTFTGSPPVG
O85973_SPHAR/26-487.IEFFVEMAD......LLPP------------GVINVV...TGY.GADVGEALV.T--------SPDVAKVAFTGSIATA
Q7WBK1_BORPA/13-471.WILADVMRE.A....GLPA------------GVFNLV...LGA.GQ.AGAALV.A--------HEAVAAVSFTGSVATG
Q6FBY4_ACIAD/20-482.LRLAEIARE.I....GFPE------------GVFNVV...TG..NSDIGHALA.T--------HPDIAKVAFTGSTQTG
Q8FY44_BRUSU/28-490.LLLGEILAE.A....GVPD------------GVVNIV...TGT.GADVGQHMS.T--------HPHVDMVSFTGSTGVG
IOLA_BACSU/15-477.EKLVELFEK.A....GLPK------------GVFNVV...YG..AHDVVNGIL.E--------HPEIKAISFVGSKPVG
Q6SF25_9BACT/16-478.AWFAHAAEA.V....GLPK------------GAVNLV...CGY.GHQAGAALS.A--------HPDINQVVFTGSVATG
Q6BPC7_DEBHA/15-474.YILVRCFLD.A....GVPK------------NALQLVHLKPED.NPKAVELFI.R--------NKAIKKVHFTGSTSTG
Q828R7_STRAW/13-460.QLFAEAVHE.A....GVPA------------GVFNLV...TGL.GPVAGQALA.E--------HEDVDLVSFTGSTAVG
Q7NEN1_GLOVI/15-481.TALIDVFRE.A....GLPA------------GVANLV...HGT.GEETGRALV.A--------HPGVDLVSFTGSSVVG
ALDY_BACSU/15-474GTIIAKAFEH.A....GLPA------------GVLNVM...LTD.VKEIGDGML.T--------NPIPRLISFTGSTAVG
Q47943_GLUOY/25-486.LLLAEILAD.A....GLPK------------GVFNVV...TGT.GRTVGQAMT.E--------HQDIDMLSFTGSTGVG
Q75TI0_GEOSE/8-466.IELTKLIDS.I....GLPP------------GVFNLV...PGG.GSPVGETLV.T--------HPDVEKISFTGGTKTG
Q8TWC7_METKA/11-466.LRLAEILLD.A....GVEP------------LALQVV...VGP.GAELGEELA.R--------.ADFDALSFTGSRSVG
Q59095_ACICA/18-473GYVIARIFEL.A....GLPK------------GLLHVL...PG..GVEVGEALT.L--------DQNIASIQFTGSTQVG
ROCA_BACSU/45-511.AKFVEVMEE.A....GLPN------------GVLNYI...PGD.GAEIGDFLV.E--------HPKTRFVSFTGSRAVG
Q7WPN3_BORBR/33-490.IALVRIAES.A....GLPT------------GLVAVL...AGL.GHTMGNAAI.E--------HPLVRKIGFVGSPETG
ALD1_STAAS/13-470.VILAEIFDK.V....GVPK------------GVFNLV...NGD.GAGVGNPLS.E--------HPKVRMMSFTGSGPTG
O50203_XANAU/26-493.LVLAELIAD......LLPP------------GVLNIV...NGF.GLEAGKPLA.S--------SSRIAKIAFTGETTTG
Q6W1I3_RHISN/34-497.LRFAELVQE.A....GIPD------------GVVNIV...TGK.GSIIGAAMS.T--------HPGINKVTFTGSTPVG
Q7VSP3_BORPE/17-482.LRLVEAFEQ.A....GLPP------------GVLNLV...TGS.ASAIGAAIT.Q--------ASQVRAVSFTGSTAAG
Q9L124_STRCO/18-473GVVIARIFEE.A....GLPA------------GVLHLL...PGD.G.SVGRAVV.E--------APEVRVISFTGSTPVG
Q6JHN1_9PSEU/12-470.LKVARTALE.A....GLPA------------GVLNVV...PGL.GAQAGAALA.G--------HAGIDHLSFTGSVPVG
BADH_SCHPO/29-495.LEFALICKE.A....GLPD------------GVLNVI...IGS.GKESGAALS.C--------HPKIAYLAFTGSLATG
Q59702_PSEPU/20-480GLLLAHIFEE.A....GLPK------------GVLSVV...VGS.GSEIGDAFV.E--------HEVPGFISFTGSTQVG
MSC7_YEAST/104-587.EFFVELIRK.CLEACDEDP------------DLVQLCYCLPPTENDDSANYFT.S--------HPGFKHITFIGSQPVA
Q73WS7_MYCPA/19-482.LALARLIDEHT....DIPP------------GVVNVV...TPS.GVEAAKLLT.T--------DPRIDMVSFTGSSAVG
GAPN_PEA/24-484.LHMVHCFHL.A....GFPK------------GLISCV...TGK.GSEIGDFLT.M--------HPGVNCISFTGG.DTG
Q6MF92_PARUW/536-989.WHLAQIFWE.A....GISQ------------QVLQFV...VCE.DEPVGSALI.Q--------DSRVNAVVLTGATETA
Q8CN25_STAES/16-475.LRLAELFRA.S....TIPA------------GLIQIV...PGT.GETVGTQLA.S--------HKDIQLISLTGSMRAG
O87842_STRCO/48-500TLACALAARE......GLPV------------TLL......SGG.GRELSQALV.R--------APEIGCVSFVGGRDTG
AL7A1_DICDI/28-492.LAVSKIIEK.VLVENDVDP------------AVCCVL...IGP.GRTVGEQMI.Q--------DKRFGLISFTGSTEVG
Q6CRD2_KLULA/26-495.LYFAKLVKE.A....GFPA------------GVFNVL...SGT.GASVGSAIV.K--------HTGVDKIAFTGSTAVG
Q885F4_PSESM/28-486.LVVGVLIER.A....GVPK------------GLVNVI...AGF.GHSIGQAFI.A--------KADIRKVVFVGSPATG
Q6AKR4_DESPS/50-520.IAIQHIIAR.VLKKNKLPE------------GIFSLI...CGS.GKDIGDLML.A--------DTRLPLISFTGSVRTG

PF07368

Q9VAW6_DROME/82-298--------------------------------------------------------------------------------
Q9VYG8_DROME/38-250--------------------------------------------------------------------------------
Q9W2S6_DROME/22-243--------------------------------------------------------------------------------
Q8T485_DROME/35-252--------------------------------------------------------------------------------
Q9W1T5_DROME/37-260--------------------------------------------------------------------------------
Q9V9P6_DROME/64-279--------------------------------------------------------------------------------
Q9VI33_DROME/97-311--------------------------------------------------------------------------------

PF00815

HISX_ECOLI/17-428...ADEILYA------AQLC------------GVQDVF---NVG-GAQAIAALAFG.TES....VPKVDKIFGPGNAFVT
HISX_BACSU/10-423GLLSPGVLVA------AAEL------------GIKDIY---KMG-GAQAIAALAYG.TET....IEPVDKITGPGNIYVA
HISX_ARCFU/2-402GKVNPLTLVA------LDIA------------EFDEVY---KAG-GAQAIAAMAYG.TET....VEKVYKIVGPGNIYVT
HIS2_NEUCR/445-864GTITPEIVYV------AHKV------------GAESIV---LAG-GAQAVAAMAYG.TES....ITKVDKILGPGNQFVT
HISX_METTH/13-425GSVPDAVLVA------ADMA------------GASEIY---RVG-GAQAVAAMAYG.TET....IRPVDKIVGPGNIFVT
HIS2_PICPA/422-837GTLTPEVIYV------AHKV------------GAKCIV---LAG-GAQAVAAMAYG.TET....VPKCDKIFGPGNQFVT
HISX_HAEIN/14-423...SDEILYT------AHLC------------GVETIY---AIG-GAQAVFAMAQG.TES....VAKVDKIFGPGNAFVT
HISX1_SYNY3/15-432GKVEPVSLVT------ARMA------------GVDEVY---KLG-GVQALAAIAYG.TKT....VSKVDKLIGPCSIYGA
HISX_STRCO/18-434GIPHPTILAA------CALL------------GVDEVY---AAG-GATAVAMFAYG.TES....CPPANMVTGPGNIWVA
HISX_BRAOC/46-459GSICKEVLYC------AKRA------------GVTHIL---KAG-GAQAIAAMAWG.TDS....CPKVEKIFGPGNQYVT
HISX_BUCAP/18-429...DNTILYA------ANIC------------GVDKIF---QMG-GAQAIAALAFG.TKN....IPKVDKIFGPGNAYVT
HIS2_KLULA/366-785GRVSPEVVYV------ASKV------------GASKIV---LAG-GAQAIAAMAYG.TES....VPKVDKILGPGNQFVT
HISX_MYCSM/24-444GRPHPTILAA------AALL------------GVDEVW---AVG-GAQAVALLAYGGTDTDGAELAPVDMITGPGNIYVT
HISX_AQUAE/18-425.KPNKYTLAA------AYIA------------GVSRVF---QVG-GAQAIGALAYG.TEK....IPKVDKIVGPGNIYVA
HIS2_CANAX/412-832GKLTPEVVYV------AHKL------------GAKCIV---MAG-GAQAVTAMAYG.TES....VLKCDKILGPGNQFVT
HISX_METJA/18-429GKGNPATLIA------GDIV------------GVSAIY---KVG-GVQAIGALAYG.TET....IPKVDIIVGPGNIYVT

PF05893

Q8G6W7_BIFLO/65-480KLIAG.KVA-------G----SKPCLGYGAKV-----GLAFIGREALRPD.T-Y-ADTVHRVAVDI-ATYDQQSCLAPQT
Q7MZU4_PHOLL/30-413TAIRS.QLR-------P----GCRWIDWGHRI-----SFAYFDPMA.....A-S-DADYDALADDV-CRFDQQACSSPQC
Q7NQ23_CHRVO/30-413SAIRA.RLP-------A----GCRWIDWGHRV-----SFAYLDPAA.....A-A-DEALDALADDI-CRFDQQACSSPQA
Q3KD56_PSEPF/30-413QAIRQ.QLA-------P----GCRWIDWGHRI-----SFIYLTPAA.....A-T-PEALDAVADEV-CRLDQQACSSPQW
Q93CP6_PHOLU/52-446NWAVE.HAP-------P----YADVIKFGSKK-----SFCIIDNPV.....D-L-TSAATGAAHDI-CFYDQRACFSAQN
LUXC2_PHOLE/50-444KWATE.HAP-------S----HADILKFGPKK-----SISIVDNPT.....D-I-KAAAIGVAHDI-CFYDQQACFSTQD
LUXC_VIBFI/51-445KWAVK.YSP-------P----HVDILKFGPKK-----SLSIIEAPK.....D-I-EAAAMGVAHDI-CFYDQQACFSTQD
Q4A539_9GAMM/49-442KWAVK.HSP-------H----HVDIVKFGPKK-----SLSIIDDPE.....D-I-TAAATGVAHDI-CFYDQQACFSTQN
LUXC_VIBHA/49-443DWAVK.HSP-------S----HIDVLKFGPKK-----SFTVLDHPA.....D-L-EEAASGVAHDI-CFYDQNACFSTQN
A8LEK2_FRASN/68-470NNVIK.YLG-------P----GFQLVSFDPKT-----SISMVGREAFASEEA-L-DTAAELAAGDV-MVLNQEACVASRF
Q97GS8_CLOAB/45-446RIIGEMCAK-------Y----QKHMIMHGAKI-----SFEVVDKCD.....D-L-NKVSEEIAKDI-ICWEQKACLSPRV
A6LV85_CLOB8/35-425KTLSVLPKK-------T----TCKDVIFGPKY-----SFAVFEKSAMESL.K-I-TKTFDNFAKDI-ISFDQRACSSPQV
Q9KV99_VIBCH/423-818ESVSGLPKK-------Y----NSQDILFGPKL-----SMMVVGSDALDSDKA-I-RKLIRRAATDS-SVFDQFACASPHT

PF00171

Q7CTQ3_AGRT5/29-491RRFLRY.AA.DSN...L....KRIVLECGGKN.....PAVVLDDAE-----D.L.DLVAEQVVNGA.FWNMGENCSASSR
Q7CSM1_AGRT5/15-474KHLAAL.AG..KH...M....KRATMELGGHA.....PVMIFDDA.-----D.I.EKAIEVTSLAK.FRNAGQVCVAPTR
Q7D3N3_AGRT5/14-476RTIGAI.GA..KR...M....KRFGLELGGKT.....PMIVFDDA.-----D.L.EAMLPVLEKAL.TIFAGQFCMTGSR
Q7CVT1_AGRT5/28-485RILLTQ.SA..AT...V....KKASLELGGHA.....PFIVFADA.-----D.L.TEAVKGCLGAK.FATSGQDCLAANR
A9A1B_DANRE/49-507KKIMEM.AS..RG...V....KAVTLELGGKS.....PLIIFEDT.-----D.L.ENAVRGALMAN.FLSQGQVCSNGTR
BETB_ECOLI/15-479KKVMANSAA..SS...L....KEVTMELGGKS.....PLIVFDDA.-----D.L.DLAADIAMMAN.FFSSGQVCTNGTR
ALDA_ECOLI/18-475EKIMAT.AA..KN...I....TKVCLELGGKA.....PAIVMDDA.-----D.L.ELAVKAIVDSR.VINSGQVCNCAER
ASTD_PSEAE/10-467NLLHSQFGG..QP...Q....KILALEMGGNN.....PLVVEEVA.-----D.L.DAAVYTIIQSA.FISAGQRCTCARR
ALDH6_YEAST/34-496KSVAVDSSE..SN...L....KKITLELGGKS.....AHLVFDDA.-----N.I.KKTLPNLVNGI.FKNAGQICSSGSR
CROM_ENTDO/24-487KLVMQA.AG.SSN...L....KRCSLELSGKC.....PVVVFPDT.-----D.L.DFAVQQAHEAA.FQNMGQCRWSGSR
O66573_AQUAE/12-471DIIARQ.VG.......I....KKLVLELGSNS.....AIILHKDG.-----N.L.EKAVEKTVQGG.YAIAGQVCISVQR
Q6BX25_DEBHA/48-514KLLMSQ.SS..ST...L....KKLSMELGGNS.....PFIVFNDA.-----D.I.DKAVDGAIGSK.FRSSGQTCICTNR
Q93HF8_STRAW/48-523LRFEQQCVA..HG........KKPILELAGND.....GIVVWKDA.-----D.V.KWAAEAITES..FFGSGQICMVPNY
LADH_METJA/7-459ELITKK.AG.......F....KKIALELGGVN.....PNIVLKDA.-----D.L.NKAVNALIKGS.FIYAGQVCISVGM
Q739I7_BACC1/23-485KTIMRN.AS..EN...L....IPVSLELGGKS.....ANIVFEDA.-----D.L.DEAVQGSIEAI.YRNQGEICLAGSR
O33455_PSEPU/24-488KKIVEY.AL..GN...M....KRVTLELGGKS.....PSIVFADA.-----D.L.DQVGLGAALAV.FFNSGQICFAASR
O86742_STRCO/16-473MSVAES.AS..KD...L....KRVHLELGGKA.....PVVVFEDT.-----D.I.PKAVEGISEAG.YFNAGQDCTAATR
Q7W0D6_BORPE/10-472RRVAE...AAIGR...M....AKVQLEMGGKN.....PLVVLNDA.-----D.L.KVAVDCAVNGA.FFSTGQRCTASSR
O52642_9PSED/19-476RLIGEK.CG..RM...L....KKVALELGGNN.....VHIVLPDA.-----D.L.DGAVRCAAWGT.FLHQGQVCMAAGR
Q7UJE5_RHOBA/56-500KRVLRQSAE..TL........TPSIVELSGVD.....AAIALPGA.-----D.V.NRVIDSLAFGL.LFNSGATCIGPRR
Q98LH9_RHILO/20-482SRVVGN.TS..RH...L....VKSSVELGGKS.....ANIVFADA.-----D.L.EAAADGALMGV.FFNNGECCVSGSR
Q6ABP5_PROAC/22-479ANLLGK.AA..KH...V....LRTSMELGGNA.....PFIVFDDA.-----D.L.DQAIIGAKGAK.MRNMGEVCIAANR
Q6ALY1_DESPS/13-480RHIYET.AT..AN...G....KRVQALCAAKN.....HALVLEDC.-----N.L.ERTAQGIINAF.CGCAGARCMALPV
Q82GU8_STRAW/29-495QRIAEV.CG..RG...M....KRQLMELGGKG.....AALVFEDA.-----D.L.ASAVSGIGTTF.SFYSGQICTAPTR
Q6N3D4_RHOPA/38-498AAIMAQ.GA..PT...L....KRVHFELGGKN.....PVIVFGDA.-----D.L.DRALDAVVFMI.YSLNGERCTSSSR
ALDA_STAAS/21-483YQVAEA.AA..KH...L....VPATLELGGKS.....ANIILDDA.-----N.L.DLAVEGIQLGI.LFNQGEVCSAGSR
Q8A340_BACTN/495-936QNIAKANPT............TPLSAETGGKN.....VIILTASG.-----D.R.DHAIMNIVTSA.FGNAGQKCSACSL
Q6PW33_9RALS/11-473RKIVQA.SS..GN...L....KKVQLELGGKG.....ANVVFGDA.-----N.L.DAVVQGSAFGI.FHNQGQACIAASR
BETB_BACSU/11-476KKIMRA.AS..GN...V....KKIALELGGKN.....PNIVFKDA.-----D.L.EVAVDQALNAV.FFHAGQVCSAGSR
P74275_SYNY3/509-973CRIYAD.AALVQP...GQKHLKRVIAEMGGKN.....AIIVDESA.-----D.L.DQAVAGAVYSA.FGYTGQKCSACSR
O06837_PSEFL/29-498RIIGSA.CG..RS...L....KAVSLELGGKS.....PVIVLADC.-----D.P.QEAAEGAAAAI.FFNHGQVCTAGSR
Q8GPZ0_PSEAI/20-479LAVHAA.AA..GT...L....THVHLELGGKD.....PAYVRPDA.-----D.I.ATAAAEIADGC.FSNAGQSCCSVER
Q7WPE0_BORBR/13-475RSIMAE.AG..RH...L....KRTTLELGGKS.....AAVLLPDA.-----E.L.ERALPVVLRMA.VANSGQACVSQSR
Q6AA40_PROAC/499-947KLFRSWRHD............LPVLAETSGKN.....SIIVTENA.-----D.Y.DLAAADIIKSA.FGNAGQKCSAASL
P96405_MYCTU/17-478REVGRR.AA..EM...L....KPCTLELGGKS.....AAIILEDV.-----D.L.AAAIPMMVFSG.VMNAGQGCVNQTR
Q8ELI8_OCEIH/14-471RNISQI.AG.......I....KKTLFELGGNA.....ATIVHQDA.-----D.I.ETAARLCAKTG.YSNSGQSCISVQR
Q9RZE6_DEIRA/24-482RLLYQQ.AA..GT...I....KRVSLELGGHA.....PFLVFDDA.-----D.L.ERAASEVVASK.FRNSGQTCVCTNR
AL1L1_HUMAN/430-898KHIMKS.CA.ISN...V....KKVSLELGGKS.....PLIIFADC.-----D.L.NKAVQMGMSSV.FFNKGENCIAAGR
ALDH5_BACSU/16-474SYIGQL.AM..KH...F....KKPLLELGGNS.....AFIVLEDA.-----D.I.EYAVNAAVFSR.FTHQGQICMSANR
Q97UA1_SULSO/11-474KRIYKL.VGNKNR...M....TRIQLELGGKN.....ALYVDKSA.-----D.L.TLAAELAVRGG.FGLTGQSCTATSR
Q92XQ0_RHIME/15-479AHLYSL.AA..KD...V....KRVSLELGGKS.....PNIVFGDA.-----D.L.DNAVRGVVGGI.FGAVGQTCIAGSR
O24897_HELPY/516-965YKMLKANPT............LALSAETGGKN.....ATIVSKMA.-----D.R.DQAIKNVIHSA.FSNSGQKCSATSL
Q18822_CAEEL/36-498KKIQEDGAK..LN........KKVSLEMGGKN.....PGIVYSNY.-----R...KSDIASIARSS.FLNQGEICLCTSR
O49218_ORYSA/49-511MHIYSR.AS..AK...G....KRVQSNMGAKN.....HAIILPDA.-----D.R.DATLNALIAAG.FGAAGQRCMALST
Q8KVX3_9RHOB/30-494KLLMTYAGQ..SN...M....KRVTTECGGKT.....PQIVFADY.-----DNL.DKAVTSAVYGI.YGNMGEMCNAGSR
Q20352_CAEEL/214-676KKIMKACAD..RN...I....KPVTLELGGKS.....ALIVFDDA.-----D.I.DSAVSCAMMAN.FYSQGQVCSNASK
Q88PZ0_PSEPK/11-471SQVMRS.AS..AQ...C....RPVTLELGGKS.....AIVVFDDC.-----D.V.DQAVEWIVAGI.SWNAGQMCSATSR
Q881E4_PSESM/24-482RKVAEA.AG..RN...L....KKVSLELGGKN.....PLVILEDA.-----D.L.DLAASNAAFGA.WLHQGQICMATGL
Q6HJ76_BACHK/11-470IGIKAK.AG.......L....KRVTLELGSNA.....AVIIDEDV.-----E.LTDELIERVKWGA.FVNNGQVCISVQR
Q95TY8_DROME/95-558RHVHKLVSDRMERYICF....PRLVAECPGQN.....FHFVHASA.-----K.V.ESVVSATVQAA.FGFAGQYANSLSR
Q8ZV31_PYRAE/12-467REIASK.AG..GA...L....KTVTLELGGSD.....PLIILDDA.-----D.L.NLAVRIAVFGA.FFHQGQICTSSKR
Q6MQ98_BDEBA/11-457EQIAKAGLS..QF........KKLQLAGSVKN.....SSVVLSGT.-----D.F.QAQMAEILKSF.LVGQGQLCWNSSR
Q9AH09_RHOER/16-479QQIGRM.AA..DR...L....ITASLELGGKS.....ALVAFGDS.-----S...PKAVAAVVFQAMYSNQGETCTAPSR
Q6F9F7_ACIAD/12-472KHIVRN.SA..EN...L....AKVSLELGGKS.....PFIVFADT.-----D.I.NSALNAQIAAI.FAATGQSCVAGSR
Q70Q17_RICRI/17-471KILYQN.AA..NT...L....KRLSLELGGNA.....PFIITADN.-----N.L.EKVVSDLVIAK.TRNSGQSCTSPNR
Q92UV7_RHIME/21-480KLIAAN.....AH...Y....KRQVLELGGND.....PLIILNDLS-----DDDLARAADLAVAGA.TKNSGQRCTAVKR
Y4UC_RHISN/49-507EAISRA.AG.......L....KKLAMELGGNA.....PVIVMNDC.-----D.F.DKAVEGCVSGA.FWAAGQNCIGAQR
Q6MMT9_BDEBA/20-477QHVYQR.GT..AL...G....KRVLALGGAKN.....HIVLLPDA.-----N.P.DLTGAGISDSF.TGCAGQRCMAAAV
Q703Z2_THETE/51-524MRLYRLFTQ.......RQPWPKPIVLEMGSKN.....PTVVTAKA.-----D.L.EKAAEGVVRAA.FGFGGQKCSATSR
Q73Y73_MYCPA/6-480RLIVKA.AA..GN...L....KRLTLELGGKS.....PLIMFDDA.-----N.L.DKAIMGAGMGL.LAGSGQNCSCTSR
Q8FS05_COREF/26-487RILGET.AG..RR...L....IGFSAELGGKN.....PLIIAEDA.-----D.L.DKAVDGAVHGT.ISNSGQLCVSIER
Q93P88_9BACT/17-480QQIFRT.AA..EN...L....IHVQLELGGKA.....PCIVFDDA.-----D.L.EQAVEGAFHSR.FDNCGQVCTSNER
YF19_SCHPO/31-493RMVMRAAAS..SN...L....KKVTLELGGKS.....PNIVFNDA.-----D.L.DSAAVWTNYGI.FYNSGQVCCAGSR
Q8FS49_COREF/31-498RKIASA.CG..EL...L....RPVTLELGGKS.....SAIVLPDA.-----D.M.SVLSARLIRSC.MRNTGQTCYISTR
O34184_HALVO/20-485KRVSGI.AG..EN...L....AVPAMELGGNN.....AHVVTEGA.-----D.V.DRAADAAVFGS.FVHQGQVCISINR
ALDHX_YEASX/49-508RVVSKL.APEQVM........KKVTLESGGKS.....TMAVFIQH.-----D.V.TWAVENTQFGV.FDRQGQCCIAQSG
Q9KC36_BACHD/16-473EKIARS.AG.......V....KKLAMELGSNS.....PTIVLQDA.-----E.L.MEAVASCVSGA.FCAAGQNCIGVQR
Q721Q0_LISMF/21-482QTLFKQ.SA..ET...L....KKISLELGGHA.....PFIVFDDA.-----N.L.DAAVNDLVAAK.FRNNGQVCVSPNR
Q6FDG9_ACIAD/11-475RHLAHI.AA..DK...L....ITTSLELGGKS.....PTIVLPDA.-----D.I.ELAAKGIAYGI.FSSAGQACIAGSR
PUUC_ECOLI/28-489KQLLKD.AG.DSN...M....KRVWLEAGGKS.....ANIVFADCP-----D.L.QQAASATAAGI.FYNQGQVCIAGTR
ABDH_ECOLI/11-470EHIISH.TA..SS...I....KRTHMELGGKA.....PVIVFDDA.-----D.I.EAVVEGVRTFG.YYNAGQDCTAACR
BADH_AMAHP/16-485SKVMSS.AA..QL...V....KPVTLELGGKS.....PIVIFEDV.-----D.L.DKAAEWTAFGC.FWTNGQICSATSR
O24829_ACISP/12-482EVIMKA.AA..KG...I....RDISLELGGKN.....AALVFADC.-----D.M.DKAIEGTMRSA.FANCGQVCLGTER
Q7UFE0_RHOBA/24-485QLIMKN.SA..QS...L....KRLTFELGGKS.....PNVIFSDA.-----D.L.DAAVQGSFVGL.YLNQGQCCCAGSR
P83849_THETH/46-512LKIYEA.AGRLAP...GQTWFKRAYVETGGKN.....AIIVDETA.-----D.F.DLAAEGVVVSA.YGFQGQKCSAASR
Q73RK8_TREDE/20-482REIIAH.SA..KL...V....KDIALELGGKS.....PNIFFEDV.-----D.I.EQAARFAVYGF.TNHAGQICVSGTR
Q6L285_PICTO/9-471QRIMEK.AS..KN...M....AKLILELGGKA.....PFMVWKDA.-----N.I.ERALKSLVWAK.YLNVGQSCIAAER
Q82K12_STRAW/25-486RRVAEI.AT..ST...V....KRLHLELGGKA.....PFVVFDDA.-----D.L.DAAVHGAVAGS.LINTGQDCTAATR
Q6G1A0_BARQU/13-473KDISKN.AS..ST...L....KRVCLELGGKG.....ANIIFADA.-----D...TNALQRGVHHC.FYNSGQSCNAPTR
Q7S5U4_NEUCR/22-482KLIQEE.AA.KTN...L....KSVTLELGGKS.....PAIIFDDA.-----N.I.EQALTDTMSSI.VLNAGQVCIANSR
Q88LI4_PSEPK/30-488REIGKL.AA..DR...I....IPLSLELGGKS.....PNIVFEDA.-----D.L.DRAVAGSVFAF.TVNTGQVCLAGTR
O85031_9RALS/11-472RIIAQK.SA..QH...L....KRCLLELGGKS.....PLIVLDDA.-----D.I.DAAVKAAVFGS.FLFQGQICMSTER
ALDH1_BACSU/18-484KIIGQ...AALAR...G....AKYQLEMGGKN.....PVIVADDA.-----D.L.EAAAEAVITGA.FRSTGQKCTATSR
Q7UYE1_RHOBA/30-491RLVGES.CG..RN...L....VPVKLELGGKG.....AAVVFDDV.-----D.V.KATAQALVGAI.TFHTGQVCCDATR
Q74E56_GEOSL/13-471VQIKER.SG.......L....KRVTLELGSNS.....PTIIEDDG.-----D.V.DAAVARCVVGS.FANSGQVCISVQR
O85973_SPHAR/26-487RRIIQY.AS..AN...I....IPQTLELGGKS.....AHIVCGDA.-----D.I.DAAVESATMST.VLNKGEVCLAGSR
Q7WBK1_BORPA/13-471KRIAAAAAG............KRIQLEMGGKN.....PLIVLDDA.-----D.L.DTAVACAIDGA.FLYAGQRCTASSR
Q6FBY4_ACIAD/20-482RSILQA.SI..AD...F....KRVTLELGGKS.....PVILHKDA.-----D.L.DKAIPTIAMGC.FFNTGQVCYAGTR
Q8FY44_BRUSU/28-490KLTMAN.AA..QT...L....KKVSLELGGKN.....PQILFPDA.-----D.M.DAFIDAAVFGA.WFNAGECCNAGSR
IOLA_BACSU/15-477EYVYKK.GS..EN...L....KRVQSLTGAKN.....HTIVLNDA.-----N.L.EDTVTNIVGAA.FGSAGERCMACAV
Q6SF25_9BACT/16-478IAIASA.AA..KN...V....VPCVLELGGKS.....AAIVHSDA.-----D.L.VAMETDIRKGI.FINAGQVCSAMSR
Q6BPC7_DEBHA/15-474RAIATI.AA..SN...L....KQCLLELGGKN.....YSIVEEDA.-----D.L.DKASKNILWSA.WCHMGQICMSTDK
Q828R7_STRAW/13-460RQIGAT.AG..AA...V....KRVALELGGKS.....ANVILPSA.-----D.L.AKAVNVGVANV.MANSGQTCSAWTR
Q7NEN1_GLOVI/15-481AEVASV.CGRTHK.........RVCLEMGGKN.....AQIVMEDA.-----D.L.ELALKGALWGA.FGTTGQRCTATSR
ALDY_BACSU/15-474RHIGEI.AG..RA...F....KRMALELGGNN.....PFAVLSDA.-----D.V.DRAVDAAIFGK.FIHQGQICMIINR
Q47943_GLUOY/25-486KSCIHA.AA.DSN...L....KKLGLELGGKN.....PIVVFADS.-----N.L.EDAADAVAFGI.SFNTGQCCVSSSR
Q75TI0_GEOSE/8-466RWIYEQ.GA..RR...L....KRVSLELGGKS.....PLLIFDDA.-----D.L.ASTIEWALFAS.FFNQGEVCVAASR
Q8TWC7_METKA/11-466EHLREI.SP.......I....PRITLELGGND.....PVIVDETA.-----D.V.EAAAEAAVRGA.CYHAGQVCIAVER
Q59095_ACICA/18-473RIVGAN.AA..KT...L....KKVSLELGGKN.....SLIILDDA.-----D.I.ELAAENIAWGA.FLHSGQICMTSGK
ROCA_BACSU/45-511CRIYER.AAKVQP...GQKWLKRVIAEMGGKD.....TVLVDKDA.-----D.L.DLAASSIVYSA.FGYSGQKCSAGSR
Q7WPN3_BORBR/33-490AKVAGA.AA..RV...V....KPCVLELGGKS.....ANIVFPDA.-----D.L.DQLCEATVKSM.FIGAGQTCVAPSR
ALD1_STAAS/13-470SKIMEK.AA..KD...F....KKVSLELGGKS.....PYIVLDDV.-----D.I.KEAAKATTGKV.VNNTGQVCTAGTR
O50203_XANAU/26-493RLIMQY.AS..QN...L....IPVTLELGGKSPNIFFADVVAEDD.-----DFF.DKAVEGFVM.F.ALNQGEVCTCPSR
Q6W1I3_RHISN/34-497QEVGRT.AV..GN...L....KHVTLELGGKS.....PVLVLDDA.-----D.L.QSAAVAVANGV.FFNSGQVCDAGTR
Q7VSP3_BORPE/17-482EQIHRSVDM.......T....TRTQMELGGKN.....PLIVMADA.-----D.L.DRAVDLVVKGG.FSLSGQACTGTSR
Q9L124_STRCO/18-473RAIGEQ.AG..RL...L....KRAHLELGGNN.....ALVVLPGA.-----D.V.AKAASAGAFGS.YLHQGQICMTTGR
Q6JHN1_9PSEU/12-470AAVAHA.AA..EN...V....IPVVLELGGKS.....PNIVFPDA.-----D.L.DAAIPVIVKSM.LQNAGQTCSAGSR
BADH_SCHPO/29-495KKIMHA.AA..EN...I....VPLTLELGGKS.....PLIICEDA.-----D.L.SLAIPSAAFAI.FFNQGEACTAASR
Q59702_PSEPU/20-480RNIGRI.AAGGEH...L....KHVALELGGNS.....PFVVLADA.-----D.L.DQAVNAAVVGK.FLHQGQICMAINR
MSC7_YEAST/104-587HYILKC.AA..KS...L....TPVVVELGGKD.....AFIVLDSAK-----N.L.DALSSIIMRGT.FQSSGQNCIGIER
Q73WS7_MYCPA/19-482RQVMSA.AG..DT...I....KRILLELGGKS.....ASIVLDDA.-----N.VTDEMLEQMLFQSCSLHAGQACILHSR
GAPN_PEA/24-484IAISKK.SG.......M....IPLQMELGGKD.....ACIVLEDA.-----D.L.DLVAANIIKGG.FSYSGQRCTAVKV
Q6MF92_PARUW/536-989KLFLRLRAD............LDLMAETGGKN.....TMIITSMA.-----D.R.DLAIKDLVQSA.FSHAGQKCSACSL
Q8CN25_STAES/16-475KSVYEN.AA..QT...V....KKVNLELGGNA.....PVIVTSNA.-----D.L.DKAVNYIVTAR.INNAGQVCTCPER
O87842_STRCO/48-500ADVATALADLG..........KRHILEQEGLN.....TWGIWNFT.-----D...WDALTRTVPKL.FDYAKQRCTAYPR
AL7A1_DICDI/28-492RRISST.VH..GY...F....GKTILELGGNN.....AIVVAEDA.-----D.I.ELVLRAVLFAS.VGTTGQRCTTCRR
Q6CRD2_KLULA/26-495QIIQQQ.SA..VN...L....KPITLECGGKS.....ANMIFEDC.-----D.L.EQAVKWSAWGI.FNNMGQICSGTSR
Q885F4_PSESM/28-486RHIAVA.AA..QR...C....IPAVLELGGKS.....ANIVFDDA.-----D.L.EVALRGAQAAI.FSGAGQSCVSGSR
Q6AKR4_DESPS/50-520RHAAQI.IA..GR...L....GKSLLELGGNN.....SIIISPEA.-----D.L.AIAIPAVVFGA.VGTAGQRCTTTRR

PF07368

Q9VAW6_DROME/82-298-------------------------------------MMVIFEDG------D-V-NCALHHLVESL---QDPFALDAVAV
Q9VYG8_DROME/38-250-------------------------------------LMVVFEDG------D-L-HSARHQLLQSL---QNPFAEGSVAT
Q9W2S6_DROME/22-243-------------------------------------LLVICQNA------D-V-AKAMQPLLHAL---KQPFAPGLVVS
Q8T485_DROME/35-252-------------------------------------FMCVCKEG------D-L-NTAAYCLAELM---HEPFQPFPMAT
Q9W1T5_DROME/37-260-------------------------------------MMVLFASG------D-M-DQVIEAIVSDM---IHPIGTGLVAS
Q9V9P6_DROME/64-279-------------------------------------LMIIFEEG------D-I-NSALHFIIESV---HNPFASNAVAM
Q9VI33_DROME/97-311-------------------------------------LMILCEDG------D-I-NCALHYLVESL---HDPFACNAVAT

PF00815

HISX_ECOLI/17-428EAKRQVSQRLDGA--------A.IDMPAGPSE-----VLVIA---------D---SGATPDFVASD-LLSQAEHGPDSQV
HISX_BACSU/10-423LAKREVFG....D--------VDIDMIAGPSE-----IVVLA---------D---ETAIPSEIAAD-LLSQAEHDKLSSC
HISX_ARCFU/2-402AAKLLVAK....D--------VAIDMPAGPSE-----ILVIA---------D---ETANADFIACD-CLAQLEHDPMAVA
HIS2_NEUCR/445-864AAKMFVSNDTNAA--------VGIDMPAGPSE-----VLVIA---------D---KDANPAFVASD-LLSQAEHGVDSQV
HISX_METTH/13-425AAKKLVYG....E--------VDIDFPAGPSE-----VLIIA---------D---ETASPEYIALE-ILAQAEHDPQAAS
HIS2_PICPA/422-837AAKMMVQNDTSAL--------CSIDMPAGPSE-----VLVIA---------D---KYADPDFVVSD-LLSQAEHGIDSQV
HISX_HAEIN/14-423EAKRQVAQ..NST--------A.IDMPAGPSE-----VLVIA---------D---ESADPEFVASD-LLSQAEHGADSQV
HISX1_SYNY3/15-432AAKRLLSG....I--------VDVGLPAGPSE-----SIVLA---------D---ETTDPKLAALD-LLIEAEHGSDSAA
HISX_STRCO/18-434AAKRFFTG....K--------IGIDAEAGPTE-----IAVLA---------D---STADPVHVASD-LISQAEHDPLAAA
HISX_BRAOC/46-459AAKMILQN.SEAM--------VSIDMPAGPSE-----VLVIA---------D---EHASPVYIAAD-LLSQAEHGPDSQV
HISX_BUCAP/18-429EAKLQVSSIFNGP--------Q.IDMLAGPSE-----LLIIA---------D---EASNADFIAAD-LLSQAEHSISSQV
HIS2_KLULA/366-785AAKMYVQNDTQAL--------CSIDMPAGPSE-----VLVIC---------D---EEADVDFVASD-LLSQAEHGIDSQV
HISX_MYCSM/24-444AAKRICRS....Q--------VGIDAEAGPTE-----IAILA---------D---HTADPVHVAAD-LISQAEHDEMAAS
HISX_AQUAE/18-425LAKKLVFG....T--------VDIDMIAGPSE-----VLVIA---------D---ERANPTWVAAD-MLSQAEHDELAAS
HIS2_CANAX/412-832AAKMYVQNDTQAL--------CSIDMPAGPSE-----VLVIA---------D---SNADADFVASD-LLSQAEHGVDSQV
HISX_METJA/18-429TAKKMVYG....E--------VAIDFLAGPSE-----VLIIA---------D---ETANAEFVALD-FIAQAEHDPNASC

PF05893

Q8G6W7_BIFLO/65-480VFVETDGALTPREVAQLLGGELENQQRKYPR---SVLS----------DAENVAIQRARTDAEMRALMGGKA..AVFASG
Q7MZU4_PHOLL/30-413LLVDSADENVLREVVSAVAAALARRATIWPA---LQTD----------IQEAAEISSQMAFLKLDHTFAELR..GSV..E
Q7NQ23_CHRVO/30-413LLVDSDDPAAIHEMARRLAAALARRAPLWPA---LTPD----------LQEAAEISARMAFHKLDQAFADDQ..GQV..L
Q3KD56_PSEPF/30-413LLVDSDDESILRAIGNDLAEAFERRSRHWPV---LLPS----------IQEASEITTRTAMARLAQSFSEVD..GQV..W
Q93CP6_PHOLU/52-446IYYM...GNQYEEFKLALIEKLNLYAHILPN---AKKD----------FDEKAAYSLVQKE.....SLFAGL..KVE.VD
LUXC2_PHOLE/50-444IYYI...GDSIDIFFDELAQQLNKYKDILPK---GERN----------FDEKAAFSLTERE.....CLFAKY..KVQ.KG
LUXC_VIBFI/51-445VYYI...GDNLPLFLNELEKQLDRYAKILPK---GSNS----------FDEKAAFTLTEKE.....SLFAGY..EVR.KG
Q4A539_9GAMM/49-442IYYI...GNKLNLFIDELEKKLNVYAKILPK---GCQN----------FDEKAAFTLTEKE.....CLFAGY..QVR.KG
LUXC_VIBHA/49-443IYFS...GDKYEEFKLKLVEKLNLYQEVLPK---SKQS----------FDDEALFSMTRLE.....CQFSGL..KVI.SE
A8LEK2_FRASN/68-470VFVEAD.QAEADRFSERL......HARIVEK---AAAS----------GDARPLDADLREQIDVLMMLDDEF..GVW.GK
Q97GS8_CLOAB/45-446VFLN..DKIDVDEFSHCLSASLRKITEVIPK---AYLS----------EWNSVKTIQDRQYCTLKYGMKNERRFKVY.SS
A6LV85_CLOB8/35-425LFIEKS.TVGINEAAQMLAQALEKSLKRYPK---VEIN----------QGAAANIINKRGE....YLISLEK..DII.CS
Q9KV99_VIBCH/423-818IFVEKGGLITPKEFAEKLASAMDKALVRLPT---QVPD----------IGQANKIRSKIAE....YAFIGE....YW.HD

PF00171

Q7CTQ3_AGRT5/29-491LIVHAK.IKDE..LLQRIGAYM.REW.RMGD...P.LD........P.QNRVGALVSKAHFDKVHSFLEDVKAENLTIVH
Q7CSM1_AGRT5/15-474FLVQDG.VADR..FLEGFVEAT.KAI.KVGN...G.LE........E.GVIMGPLANERRIPALEGLINDAVSHGAELKT
Q7D3N3_AGRT5/14-476LLVHSS.IYEL..VRDRLAERL.RAV.KVGP...A.SD........P.ASDMGPLIDKENVARVDSVVKDALSKGATVVV
Q7CVT1_AGRT5/28-485IYVQRS.LYPR..FVERFAEAT.SRL.TVGH...G.LE........T.GVDIGPMTRPSVAEKCRQQVAQALSAGARLVC
A9A1B_DANRE/49-507VFVQSS.IVPQ..FLKEVVRRT.KAI.SIGD...P.LL........D.ETRMGALVSKAHLDKVLRYVEQAKNEGAQVLC
BETB_ECOLI/15-479VFVPAK.CKAA..FEQKILARV.ERI.RAGD...V.FD........P.QTNFGPLVSFPHRDNVLRYIAKGKEEGARVLC
ALDA_ECOLI/18-475VYVQKG.IYDQ..FVNRLGEAM.QAV.QFGN...P.AE........RNDIAMGPLINAAALERVEQKVARAVEEGARVAF
ASTD_PSEAE/10-467LLVPQG.AWGD.ALLARLVAVS.ATL.RVGR..FD.EQ........P.APFMGAVISLSAAEHLLKAQEHLIGKGAQPLL
ALDH6_YEAST/34-496IYVQEG.IYDE..LLAAFKAYLETEI.KVGN...P.FD........K.ANFQGAITNRQQFDTIMNYIDIGKKEGAKILT
CROM_ENTDO/24-487AYVHES.IYEE..FVKRSVEQA.TRR.KIGD...PYEL..........DTEHGPQIDEEQYTKVLDYIKSAQEQGAKLKY
O66573_AQUAE/12-471VFVHED.LYDE..FIKRLKERV.SKL.KVGD...P.MN........E.DTDLGPMIAPSELERIQEWISEAVQKGAKIEA
Q6BX25_DEBHA/48-514LFVHES.IYDE..FASKLTKKLSETV.KLGN...G.LA........D.GTTHGPLIHGKSMNKVRSHIEDATSKGAKVLL
Q93HF8_STRAW/48-523VLVHPD.VAEA..LIAEVREQV.KGI.RPGL...PEEE..........DVLLSP...VRRSERFFRLLRQALDNGGSLVT
LADH_METJA/7-459ILVDES.IADK..FIEMFVNKA.KVL.NVGN...P.LD........E.KTDVGPLISVEHAEWVEKVVEKAIDEGGKLLL
Q739I7_BACC1/23-485LLVQES.VYEQ..FLEKFVAAV.KRI.KVGD...P.LS........E.DTDMGALVSKSHLETVDRYVELGISEGAKLAY
O33455_PSEPU/24-488LFVQDS.VYDQ..VVEAVAAAA.AQF.KVGN...G.LD........P.DTLLGPLVSRKQQERVMGYVQSGIEQGARLVC
O86742_STRCO/16-473VLVHES.VHDE..FVSALAKAA.SEI.KTGQ...P.DD........E.DVMYGPLNNPNQLKQVSGFIERLPA.HAKVEA
Q7W0D6_BORPE/10-472LIVQKG.IYPR..FVEAVRERL.QGL.KVDD...A.LA........P.GTDIGPVVDRSQFDQNLAYIAIGREEGAQLAW
O52642_9PSED/19-476HLVHRD.VAQQ..YAEKLALRA.NNL.VVGD...P.NS........D.RVHLGPLINDKQVVRVHALVESAQRAGAKVLA
Q7UJE5_RHOBA/56-500LIILNHPTTSE..ITHRLINRL..............RD..........ATEV..SVHPAARSGVADLIDNALENGAEDSL
Q98LH9_RHILO/20-482LFVQSS.IADD..FIAKVIARS.RKM.KVGD...P.FD........D.DTDVGALIDRNHLAKVTGFVKSGIEEGAQLVL
Q6ABP5_PROAC/22-479FIVHES.VAEE..FTDKMIEMM.SGL.VVGD...G.LD........E.KSEVGPMITERDREKVDGLVRSAIEAGATLRC
Q6ALY1_DESPS/13-480IVVQES.IADK..LVERITYHA.KKL.TMGK...A.WL........P.ETGMGPIVNAGHKKSILDWIARGITEGADLVL
Q82GU8_STRAW/29-495VLAQRG.VYDR..VVDQLAAYA.RRL.PVGD...P.RA........P.GTVVGPVISAAHRDRVESYVELGRKEGARVVT
Q6N3D4_RHOPA/38-498LLVQSS.IADS..FIEKLAARV.RAL.KVGH...P.LD........P.ATEVGPLIHQRHLDKVCSYVDVARKDGATIAV
ALDA_STAAS/21-483LLVHEK.IYDQ..LVPRLQEAF.SNI.KVGD...P.QD........E.ATQMGSQTGKDQLDKIQSYIDAAKESDAQILA
Q8A340_BACTN/495-936LLVERS.VYEDENFRSKLKDAA.TSL.KTGSVWNA.............GNIVGPMITNKNDKLLQAF.NLEPGESWLVPP
Q6PW33_9RALS/11-473LIVHES.IADD..LLERFTSLA.RSI.RIGD...P.LD........P.STEMGPLTSQMHRDRVLSYVDVAREQGGRVLA
BETB_BACSU/11-476LLVEDA.IHDQ..FLAELVKRA.KRI.KLGN...G.FH........A.ETESGPLISAEHRAKVEKYVEIGIEEGAKLET
P74275_SYNY3/509-973VVVLSP.VHDA..FVERFVEAT.RSL.NVGP...T.DD........P.STQVGPVIDAKAQARIQEYIEQGKAEC.ELAI
O06837_PSEFL/29-498LYVHES.IYED..VIQRLAVIG.ESI.VVGS...G.LE........Q.GVHMGPMVSKKHHENVLRHIRNGIEDGADLIC
Q8GPZ0_PSEAI/20-479IYLHEA.IRDP..FLECFRNEM.RKY.KLGH...P.MD........P.ATTIGPVVKASAADFIRSQIRGAIAMGAQAYV
Q7WPE0_BORBR/13-475LIVPRQ.RLAE..AEQALAALA.QAW.PQGD...P.LD........A.ATRLGPLANARQFERVNAMVSRALQQGARLVA
Q6AA40_PROAC/499-947IILVGQ.AYRSQRLRHQILDAA.SSI.RVGS...PSDL..........RSQMGPLAEPASGKLLDGLTKLDPGQEWALEP
P96405_MYCTU/17-478ILAPRS.RYDE..IVAAVTNFV.TAL.PVGP...P.SD........P.AAQIGPLISEKQRTRVEGYIAKGIEEGARLVC
Q8ELI8_OCEIH/14-471IYVQEE.IKDN..FIELLKQEV.SKL.KVGD...P.LD........P.HTDIGTLVDEKAAGRVIEWINEAVESGAEIIQ
Q9RZE6_DEIRA/24-482VYVQRG.VAEE..FIRLLTEKT.AAL.QLGD...P.FD........E.ATQVGPVVEQAGLDKVQRQVQDALTKGAQATT
AL1L1_HUMAN/430-898LFVEDS.IHDE..FVRRVVEEV.RKM.KVGN...P.LD........R.DTDHGPQNHHAHLVKLMEYCQHGVKEGATLVC
ALDH5_BACSU/16-474VLVHSS.IYDK..FLELYQAKV.ESL.KVGD...P.MD........P.DTIIGPLINSRQTDGLMKTVEQAIEEGAVPVK
Q97UA1_SULSO/11-474LIINKD.VYTQ..FKQRLLERV.KKW.RVGP...G..T........E.DVDMGPVVDEGQFKKDLEYIEYGKNVGAKLIY
Q92XQ0_RHIME/15-479LLVHRS.IHDE..FLEKLAVFT.KTA.RIGD...P.RK........V.ETQIGPIANSMQFEKVLGYIDIARREGAELIL
O24897_HELPY/516-965LVLEKE.VYEDENFKKTLIDAT.LSL.SVGD...PFDF..........KNKIGALADKPNEKVIKAIDELKSYENYEIPV
Q18822_CAEEL/36-498LFVQKP.IFAD..FVKSYVEEA.KKF.TVGD...P...........TTQVQIGAMNSKVHYEKVKSYIELAKKEGADILC
O49218_ORYSA/49-511AVFVGG.SEPW..EDELVKR.A.SSL.VVNS...G.MA........S.DADLGPVISKQAKERICKLIQSGADNGARVLL
Q8KVX3_9RHOB/30-494ILVQRP.IYDE..FIKRFSELT.ASNMVVGD...P.LD........P.DTTIGPLVTVEQQERVLEYIEIGKKEGATLAL
Q20352_CAEEL/214-676VLVHKS.VLKE..FTKKLVDHT.QKM.KIGD...PLKE..........DTQVGSHISAEHRNKVEGYISTAIAEGATKLC
Q88PZ0_PSEPK/11-471LLVQDG.IADA..LLPRLQAAL.ENL.RVGN...P.LT........E.EVDMGPLTSQAQWLKVASYFATAREEGLQCLA
Q881E4_PSESM/24-482ILVHES.IVAA..FTRKLADKA.RAL.TVGN...A.AR........G.QAALGPLINQRQLQHVHQVVSDSLQAGAQLET
Q6HJ76_BACHK/11-470VFVHEE.RMDD..FLSKLRKAM.ETV.VVGD...P.LI........E.ETDVSALISKKDVERIDNWVQEAVKEGANVLY
Q95TY8_DROME/95-558MYVPSS.MWPR..LREELVEAT.EQL.TI.G...DPIE........S.ETDIGAMVHINDFRRMQKLLQRTKN..MEQLC
Q8ZV31_PYRAE/12-467IIVHER.VYDV..FVKKFVERV.SQL.KVGD...P.RD........R.TVEQGPLISPRQADEMERFYQDAVSRGGRALT
Q6MQ98_BDEBA/11-457LFLLES.MSAD..FIEAMKTYL.DKLEPLMD...P...........KGTSPWTPLITSARREELQKKVQEGKVEHGKVLS
Q9AH09_RHOER/16-479LLVERP.IYDE..VVELVQARV.EAA.RVGD...P.LD........P.DTEIGPLISAEQRESVHSYVVSGTEEGATLIS
Q6F9F7_ACIAD/12-472LLIEES.IKDE..FLQRLAERV.QSI.KMGL...P.DD........M.QTEYGPLCTLKQREKIQQVVQRSVEQGAKLIT
Q70Q17_RICRI/17-471IFIEES.IYEK..FIEILKAKF.TKL.KAGD...G.FD........K.ESDVGPLINSAAIEKIQKLLADAQSKGAKLIC
Q92UV7_RHIME/21-480ILCQES.VADR..FVPLVLERA.KRL.RFGD...P.MD........R.STDLGTVIHEKAAALFEERVMRAAEEGADILY
Y4UC_RHISN/49-507ILIQSE.LYGR..FRDAFVAAT.KKL.KAGD...P.LQ........E.DTDVGPMISKQVAERTEAAVNEAIKAGATLLC
Q6MMT9_BDEBA/20-477VLAVGD.V.DH..HIQKIIQRA.QSL.VLGK...................DMGAIISKSQVQFLKDAITRAEKEGAKILL
Q703Z2_THETE/51-524LYVQRE.VYDR..FVERLVEKT.REIVKIGD...PRRR..........EVFLGPVINKSARENYRRYVADAVAAGGRLRY
Q73Y73_MYCPA/6-480IYVQRG.IYDQ..VVEGLAEFA.KML.PMGG...S.DD........P.NSVLGPLISEKQRQRVEGIVNDGVAAGAKVIT
Q8FS05_COREF/26-487IFVVGS.MYPR..FVDAYVQRL.QSI.RMEA...G.FD........W.DVEMGSLASQQQLDTVTRMVDEAVSKGAEVLT
Q93P88_9BACT/17-480LYVHES.IYNE..FMERFMEKV.KGL.KLGN...P.MD........A.ATTIGPKVNAKEVAHMEHLVTKSVEEGATVAI
YF19_SCHPO/31-493VYVQED.VYDE..FIKRMVAKA.KTL.KVGD...P.FA........E.DTFQGAQVSKQQYERIVSYIESGIAHGAKLEI
Q8FS49_COREF/31-498IIAPAS.RYEE..VVQVVADTI.AAG.RQGD...P.LD........E.DTIFGPVATASQYATVMEYIESGHAEGARAVT
O34184_HALVO/20-485HIVHES.VYDE..YVEKLTERA.AEL.PVGS...A.HE........D.DTVVGPIIDESQRDEMLGYVEETVAAGATLET
ALDHX_YEASX/49-508YTVHRS.TLSQ..IVENNLEKDPSYVLHVDT...............E.SDIRGPFILKIHFESIPRRINSAKAENSKVLC
Q9KC36_BACHD/16-473IYVEQS.VFNS..FIQSFVAQT.KQL.RLGD...K.QS........E.ETDIGPMISEKEAKRIERWVEEAKEEGARVLT
Q721Q0_LISMF/21-482IFVAKE.IKEK..FTKALVAKV.EQL.KVGN...G.LD..........DVNVGPLIREDAIDKIDKQLKNATDKGAKVLT
Q6FDG9_ACIAD/11-475LFIHSS.IYDQ..FLARLVEIT.KSL.RVGH...P.EQ........K.DVHMGSLINAAHLASVDRYVQLAKQEGGEILT
PUUC_ECOLI/28-489LLLEES.IADE..FLALLKQQA.QNW.QPGH...P.LD........P.ATTMGTLIDCAHADSVHSFIREGESKGQLLLD
ABDH_ECOLI/11-470IYAQKG.IYDT..LVEKLGAAV.ATL.KSGA...P.DD........E.STELGPLSSLAHLERVGKAVEEAKATGHIKVI
BADH_AMAHP/16-485LLVHES.IAAE..FLDRLVKWC.KNI.KISD...P.FE........E.GCRLGPVVSKSQYEKVLKFISTAKSEGATILC
O24829_ACISP/12-482VYVERS.IFDE..FVGRLKEAA.EGL.KIGP...P.DD........A.EANLGPLVSLKHREKVLSYYQKAVDDGATVVT
Q7UFE0_RHOBA/24-485VFVEES.IHEA..FVEKLTDLT.NKR.VVGN...P.FE........H.TTEQGPQIDQAQFDKIMSYIDKGNQQGASCVS
P83849_THETH/46-512LILTQG.AYEP..VLERVLKRA.ERL.SVGP...AEEN........P.D..LGPVVSAEQERKVLSYIEIGKNEG.QLVL
Q73RK8_TREDE/20-482ILVQRR.IYEP..FIKAMVETA.YKL.KPGD...G.FD........P.STTINTLISREHANTVWEYIEKGKKQNARLVC
Q6L285_PICTO/9-471LYIHED.IYDE..FMKKFIEVS.KRI.KLGD...PES............SDMGPLINKSAVETTEKYVDIARSSGYKILL
Q82K12_STRAW/25-486AYVQRP.LYEE..FVARTAALM.ETV.RLGD...P.FA........H.GTDLGPLVSHAQRDRVAGFVDRARA.YARVVT
Q6G1A0_BARQU/13-473MLVEQA.IYDK..AIRIAKDIA.EKT.KVGP...G.HQ........T.GNHIGPVVSKQQYDKIQDLIQSGIDEGATLVA
Q7S5U4_NEUCR/22-482VYVQKS.VAPK..FIEAFTKRM.ATI.RGGN...P.LD........P.QTQMGPQADEIQYKNILSYIEEGKK.SGKLAV
Q88LI4_PSEPK/30-488CLVHES.IFEK..FSKKLAGAV.EAL.QFSD...G...........E.SFGLGPLTTKAQFEQVHRYNELAIQEGAHCLV
O85031_9RALS/11-472LVVDEK.IADE..FVAKFVEKT.KQL.SAGD...PCVT........G.DCIIGPMVSPNSGDRINGLFKDAISKGAKVVC
ALDH1_BACSU/18-484VIVQSG.IYER..FKEKLLQRT.KDI.TIGD...S.LK........E.DVWMGPIASKNQLDNCLSYIEKGKQEGASLLI
Q7UYE1_RHOBA/30-491WLIHEN.IYDE..FVAECKQLM.EKV.RIGH...P.LD........P.NSDMGPVVNPKQRERVLGYQEKGTAGGAQCLC
Q74E56_GEOSL/13-471IFVHQR.RYRE..FVDKFVAAT.QKL.KVGD...P.MD........R.DCDIGPMISREELQRAVEWLGEATSLGARLET
O85973_SPHAR/26-487LFLHQS.IQDE..FLAKFKTAL.EGI.RQGD...P.LD........M.ATQLGAQASKMQFDKVQSYLRLATEEGAEVLT
Q7WBK1_BORPA/13-471IIVTEG.IHAA..FVKRLLAQT.ASL.AVGH...A.LD........E.ATVIGPVVNAEQFEKNRRYADLARQEGGTVA.
Q6FBY4_ACIAD/20-482LYVHHD.IYDE..VLARLAAFT.KTL.KIGS...S.DD........P.NTQLGPVVNARQQHSIQEFLNKAEQQGIESLD
Q8FY44_BRUSU/28-490LIVHRS.VVDA..IVGRVADLS.KKV.IVGD...P.LD........A.STQVGAIITPQHLTKVGAYVDQARKAGAAIAH
IOLA_BACSU/15-477VTVEEG.IADE..FMAKLQEKV.ADI.KIGN...G.LD........D.GVFLGPVIREDNKKRTLSYIEKGLEEGARLVC
Q6SF25_9BACT/16-478IIVHES.RHDE..LVQRAVSIA.ESL.SVG....PGADR......QTFGANMGPMVSVKQRDRAAGLVSEAVSQGAKLVT
Q6BPC7_DEBHA/15-474TYIHES.VYDA..FLKTMKATA.ESM..MKD...P.............DYKL.PHRDEGLARNIGKFVSDAVAKGAKIEY
Q828R7_STRAW/13-460MLVHAE.RYEE..AVELAAAAA.VKY......................ADRIGPLVNAKQRARVRGYIDKGVAEGARLVA
Q7NEN1_GLOVI/15-481LILHRD.IKQV..FTEKLIEQA.RQL.RLGP...G.ID........P.NTEVGPLINESQLSRVHEYIEIARQEGLKILL
ALDY_BACSU/15-474IIVHQD.VYDE..FVEKFTARV.KQL.PYGD...Q.TD........P.KTVVGPLINERQIEKALEIIEQAKTDGIELAV
Q47943_GLUOY/25-486LIVERS.VAEK..FERLVVPKM.EKI.RVGD...P.FD........P.ETQIGAITTEAQNKTILDYIAKGKAEGAKLLC
Q75TI0_GEOSE/8-466ILVQRR.VYDS..FLDQLTQRL.ASL.RIGD...P.FA........E.HTEMGPLISSSHLEKVETYIQIGLQEGGVLLQ
Q8TWC7_METKA/11-466AIVVED.VYEE..FLEAAVEVA.ESL.KVGD...P.LD........E.DTDVGPLIDDGAVEKVRRHVEDAVERGAEILT
Q59095_ACICA/18-473ILIHQK.IYQQ..VKQRVIEKV.QNF.VVGN...P.CD........K.NVTIGPLINAKQAQRVEQLVSAAVNEGATLEI
ROCA_BACSU/45-511AVIHQD.VYDE..VVEKAVALT.KTL.TVGN...P.ED........P.DTYMGPVIHEASYNKVMKYIEIGKSEG.KLLA
Q7WPN3_BORBR/33-490LIVHRS.LEQQ..VVERLLDAA.STL.EMGL...PELD..........STAIGPIHNRRQFDHVNRMIEQGRRDGARCRQ
ALD1_STAAS/13-470VLVPKK.IKDA..FLAELKEQF.SQV.RVGN...P.RE........D.GTQVGPIISKKQFDQVQNYINKGIEEGAELFY
O50203_XANAU/26-493ALIQES.IYDR..FMEKALKRV.AAI.VQGS...P.LD........P.ATMIGAQASSEQLEKILSYIDIGKQEGAEVLI
Q6W1I3_RHISN/34-497VYVQGS.VHDA..FLDELVSVT.SAL.KIAP...G.LD........R.DCYIGPLVSAQQKKVVSGYIEAGRREGAELIH
Q7VSP3_BORPE/17-482VLVDAP.VKAA..FTEKLLAKV.KAL.KVGN...S.LE........G.SFDLGPLATARQLESVMRYIEVGKQE.ARLLC
Q9L124_STRCO/18-473HIVHES.LVEE..YTAALAAKA.EAL.PVGD...P.AR........E.DVALGPIIDRRQLERVHGIVTDSVAAGAKVAA
Q6JHN1_9PSEU/12-470LLVHEE.VRDE..VLARIDEAL.RGV.RIGP...G...........PQDLDLGPLISAKQRDRVTQMVQRAADSGARQL.
BADH_SCHPO/29-495LIVHES.VADE..VLGGLVSEA.NKL.IIGN...G.LD........P.QVTLGPVVSKTQFEKIVSYIQSAINEGCKCVV
Q59702_PSEPU/20-480IIVEDS.VYDE..FVNRYAERV.KSL.PYGD...P.SK........P.ETVVGPVINAKQLAGLQDKIATAKSEGARVMV
MSC7_YEAST/104-587VIVSKE.NYDD..LVKILNDRMTANPLRQGSDIDH.LE..........NVDMGAMISDNRFDELEALVKDAVAKGARLLQ
Q73WS7_MYCPA/19-482LLLPDS.LHDD..VVDRLAALA.REV.KVGD...P.TD........P.DVQMGPLISAAQRDRVEAHIAGARSDGATLVT
GAPN_PEA/24-484VLVMES.VADA..LVEKVKVKV.AKL.SVGP...P.ED..........DSDITPVVSESSANFIEGLVNDAKEKGATFCQ
Q6MF92_PARUW/536-989AIVEAE.TYDNLHFRQQLKDSV.ESL.SIGS...PWKL..........KSKVNPLIREANPNLLRGLTQLEEGEEWLVQP
Q8CN25_STAES/16-475IFVHED.VHDD..FLNKVTSKM.KSL.TVGD...P.FD........E.NTDYGAIINQKQLDSIHEKVQDAIKNGATLMT
O87842_STRCO/48-500FVVQRQ.RFDA..FLAAYLPAV.RTL.RVGH...P.LAVAAPDDPYP.ALDFGPVINAAKAKELHDQVAEAVDRGAVPLH
AL7A1_DICDI/28-492LFVHES.LYDT..ILERLTKAY.KTI.KIGN...P.LE........E.GVLVGPLHTQSAVKEFTEGLEEIKKQGGKVVI
Q6CRD2_KLULA/26-495VFVQES.IYEE..FVAQLADHV.KKTYIVGA...P.SD........D.AVIVGPQVSKKQQERVLEYIKIGIEEGCKVPL
Q885F4_PSESM/28-486LLVQQS.IFEK..FTNALAVAA.TQF.KVGD...P.GD........P.ETQIGPINNAKQYNHVKSMVERALKDGAKLVG
Q6AKR4_DESPS/50-520LIIHES.IYDK..VRDGLTKAY.KSL.RIGS...P.LN........Q.DNHMGPLVNQDAVANYLAAVETIKDQGGEILC

PF07368

Q9VAW6_DROME/82-298ILVQEA-LAEE--IENRVKILM--------------------------KPLDARVANHPCYKRTLMKIDE..LRPKTIIG
Q9VYG8_DROME/38-250LLLQES-IADQ--FVGLVAQDL--------------------------RPLSQEVSKHPSYTSTLAKIEE..LKAKTVQG
Q9W2S6_DROME/22-243VFVHET-MRDS--FCDLVRNSM--------------------------ERMHHQAATHSSYVKAVEMLNC..LQAEVVSM
Q8T485_DROME/35-252VAVHHS-IRDE--FIERVRSRF--------------------------RQLKPHVANHPNFIRAVNELKYGLRPVKYILA
Q9W1T5_DROME/37-260VLVEES-IRDE--MIKRIRANL--------------------------KPMSERIQHHPNYLKTVKLIDR..MNCSTIHI
Q9V9P6_DROME/64-279VLVEEK-IRGE--IVERILSKL--------------------------HPLSKFVAEHPSYLAALEKCHT..SNFNIIRA
Q9VI33_DROME/97-311LFLQES-ILEE--FVDRIRDRL--------------------------EPLSTDISGHPVYIMTLERIGH..LQAKRIVG

PF00815

HISX_ECOLI/17-428ILLTPA-..AD--MARRVAEAVERQLAELP.-----------------.RAE.TARQALN..ASRLIVTKDLAQCVEISN
HISX_BACSU/10-423VFVTDS-..MA--LAETVSAEVNKQLETLP.-----------------.RRE.IAEASVR.DYGCIYVAETMVEAIETVN
HISX_ARCFU/2-402VVLTTS-..RK--VADEVEKKVKSEGDFSN.-----------------...............FAVFVVEDLAEAFEISN
HIS2_NEUCR/445-864ILIAID-LDEE--HLQAIEDEVHRQATELP.-----------------.RVQ.IVRGSIA..HSITVQVKTVEEAMELSN
HISX_METTH/13-425VLVTDS-..RD--LALEVKEMVHENIKYME.-----------------.RAN.IIRESLE.RYGMIVLTADIDEAVDFSN
HIS2_PICPA/422-837ILLAVD-MTDK--ELARIEDAVHNQAVQLP.-----------------.RVE.IVRKCIA..HSTTLSVATYEQALEMSN
HISX_HAEIN/14-423ILVATC-..ET--LAKETALAIERQLALLP.-----------------.RAE.TVRKALN..HSRIFIAESLEQAVEISN
HISX1_SYNY3/15-432LLVTHS-..AS--LAEKALGYLGEYLEKLPP-----------------WRKK.FCEDGLG.SYGGILLTDSLQASLDFIN
HISX_STRCO/18-434VLVTDS-..AE--LADAVEKELQPQVEATK.-----------------.HIEDRIRPALAGRQSAIVLVDGLDEGLRVVD
HISX_BRAOC/46-459VLVVVG-.DGV--NLKAIEEEIAKQCKSLP.-----------------.RGE.FASKALS..HSFTVFARDMIEAITFSN
HISX_BUCAP/18-429ILLTPS-..LQ--LAKKVIISINNQLKNLS.-----------------.KSD.DISTALD..NSVIILTKDLFECIKISN
HIS2_KLULA/366-785ILVGVS-LSDS--KIEALQNAVHEQAMQLP.-----------------.RVD.IVRKCIA..HSSIILCDSYEEAFKMSN
HISX_MYCSM/24-444VLVTDS-..ET--LAEATDRELANQLATTK.-----------------.HVE.RVTAALSGKQSAIVLVDDIDAGVRTVN
HISX_AQUAE/18-425ILLTPS-..EE--LANKVKEEVERLLSQLE.-----------------.RKE.IAQKSLE.KFGTIFLVKDLYHACEVAN
HIS2_CANAX/412-832ILIGVG-LSDE--KLNEFQAAVERQAKVLP.-----------------.RKD.IVAKCLA..HSYILLAKTYKEAFDLSN
HISX_METJA/18-429VITTTS-..EK--KAEEIKNKIFEEIEKAE.-----------------.RKE.IILKALE...NSAILIGDLEECIEFSN

PF05893

Q8G6W7_BIFLO/65-480---------------------HSTAWSVL------Y-RELDGSGADEDVASLMSPL.NRTVNVVAVP--D------LLDA
Q7MZU4_PHOLL/30-413---------------------EGNGWRVA------W-IQRQ........ELAPSPL.YRTLQVRPAP--R------A.QL
Q7NQ23_CHRVO/30-413---------------------SGQGWRLA------W-SMEQ........ELAPSPL.FRTVELRPAP--R------A.AL
Q3KD56_PSEPF/30-413---------------------QAPDWRVI------W-THDQ........QLAPSPL.FRSLLLKPLP--R------A.QV
Q93CP6_PHOLU/52-446---------------------VHQRWMII------E-SNAG........VEFNQPL.GRCVYLHHVD--N------IEQV
LUXC2_PHOLE/50-444---------------------ESQSWLLT------Q-SPAG........SFGNQPL.SRSAYIHQVN--D------ISEV
LUXC_VIBFI/51-445---------------------DKQAWLIV------V-SPTN........SFGNQPL.SRSVYVHQVS--D------IKEI
Q4A539_9GAMM/49-442---------------------ENQSWIII------Q-SPLD........AFGNQPL.SRSVYIHQVS--S------IEDI
LUXC_VIBHA/49-443---------------------PENNWMII------E-SEPG........VEYNHPL.SRCVYVHKIN--K------VDDV
A8LEK2_FRASN/68-470---------------------TDGHGLVI------R-SDE.........PVDFHPI.NKTANVVRVN--S------LDEA
Q97GS8_CLOAB/45-446---------------------FNADYTVI------L-SDGMPEK.....EDINKCF.YRFIFVCPYS--S------KSDV
A6LV85_CLOB8/35-425---------------------KDLKYTIL------I-DKE.........IILEEPVQHTTIFLKEIE--D------IFEV
Q9KV99_VIBCH/423-818---------------------KHLRWTVL------F-DEG.........IELVEPTYQRVITVKAVD--N------VFDV

PF00171

Q7CTQ3_AGRT5/29-491.GG............KTEKG.IFIEPTVV...DA.V-PPAS--------RLFREEIFGPILSVTTFN..T......LAEA
Q7CSM1_AGRT5/15-474.GG..........RRIGNKG.NFFEPTVL...AN.V-PVTA--------KIMNDEPFGPVAIINRFS..S......FDDA
Q7D3N3_AGRT5/14-476RGGP.......VPEGPLAKG.AFFRPSML...EV.F-DNSL--------PIVQQETFGPVITIQRFS..D......EREA
Q7CVT1_AGRT5/28-485.GG..........QDSPLGG.NFVTPTVL...AD.V-TDDM--------LIAREETFGPVAAILPFD..D......EAEV
A9A1B_DANRE/49-507.GGEP....FSPADPKLKDG.YYMTPCVL...DS.C-TDDM--------TCVKEEIFGPVMSVLTFD..T......EDEV
BETB_ECOLI/15-479.GGD......VLKGDGFDNG.AWVAPTVF...TD.C-SDDM--------TIVREEIFGPVMSILTYE..S......EDEV
ALDA_ECOLI/18-475.GG..........KAVEGKG.YYYPPTLL...LD.V-RQEM--------SIMHEETFGPVLPVVAFD..T......LEDA
ASTD_PSEAE/10-467............AMTQPIDGAALLTPGIL...D..V-SAVA--------ERPDEEFFGPLLQVIRYS..D......FAAA
ALDH6_YEAST/34-496.GG..........EKVGDKG.YFIRPTVF...YD.V-NEDM--------RIVKEEIFGPVVTVAKFK..T......LEEG
CROM_ENTDO/24-487.GG.........NKHGDKGG.YYIEPTVF...SE.V-SDNM--------KIAKEEIFGPVQLLMKFR..D......LDDV
O66573_AQUAE/12-471.GGLR....CAE......DE.TIFSPTIV...SL.V-PEDS--------KLFKEEAFAPVVAVNPYK..D......IEEA
Q6BX25_DEBHA/48-514.GGN......KRE....DLGVNFHELTVL...GG.V-TQEM--------DIFNEETFGPVAPLIKFK..S......DEEV
Q93HF8_STRAW/48-523.GGHR....TELDGTPSETG.VFLQPTVIRVDGLDR-ARTF--------DVVREETFFPLIPIVVPERDND...DALLEA
LADH_METJA/7-459.GGK.......R......DK.ALFYPTIL...E..V-DRDN--------ILCKTETFAPVIPIIRTN..E.......EEM
Q739I7_BACC1/23-485.GG........KRVESLVEG.NFYEPTIL...YD.V-DNSM--------RVAQEEIFGPVLVVIPFK..T......EEDA
O33455_PSEPU/24-488.GG..........KSVGEKG.YFLQPTVF...AD.A-APSM--------RIAQEEIFGPVVSVIRFK..D......EAEA
O86742_STRCO/16-473.GG........H..RVGDKG.YFYAPTVV...SG.L-KQDD--------EIIQREVFGPVITVQAFR..D......EDQA
Q7W0D6_BORPE/10-472.GGEP.....LK.RA..NEG.YYLAPALF...VD.C-DNSL--------RIAREEIFGPVAAVIPVD..S......YEQA
O52642_9PSED/19-476.GGT.......Y......QD.RYYQATVI...MD.V-KPEM--------EVFKSEIFGPVAPITVFD..S......IEEA
Q7UJE5_RHOBA/56-500.GQ.........YNAGRLRNTGKMHPVVL...QN.V-PDDH--------AILQSDVFAPVISIIPVQ..K......IEQA
Q98LH9_RHILO/20-482.GG.........NVAAGAVG.HFHEATIF...DR.V-EPHM--------TIFREEIFGPVLSITRFD..T......VDDA
Q6ABP5_PROAC/22-479.GG..........EIPEDKG.WFYPPTVL...SG.V-PADA--------EIMQTEIFGPVAPITTFR..T......EEEA
Q6ALY1_DESPS/13-480.DGRR.....PVVAAGCENG.YFIGPTIF...DN.V-TPEM--------SIGSEEIFGPVLSVKRVK..D......FAEG
Q82GU8_STRAW/29-495.GG.........ERPPCATG.FYVAPTLL...AD.C-TTDM--------RVVREEIFGPVVAVLPFD..D......EEEG
Q6N3D4_RHOPA/38-498.GG........APFDGPGGG.HYVQPTLV...TN.A-RSDM--------QVAQDEVFGPFLTVIPFK..D......EAEA
ALDA_STAAS/21-483.GGH......RLTENGLDKG.FFFEPTLI...AV.P-DNHH--------KLAQEEIFGPVLTVIKVK..D......DQEA
Q8A340_BACTN/495-936.............RFIDRRE.YILAPTVK...WG.V-KPES--------FSFRTELFGPLLSVACIE..N......LEEG
Q6PW33_9RALS/11-473.GGK......SPDAAGLAKG.CYVEPTIV...Q..A-KPTD--------RVAQEEVFGPFVTVSTFK..S......DEEG
BETB_BACSU/11-476.GGK......RPEDPELQNG.FFYEPTIF...SN.C-NSDM--------RIVQEEVFGPVLTVETFS..S......EEEV
P74275_SYNY3/509-973.ACD......AP.....SEG.YFVGPTVF...KN.V-DRHA--------TIAQEEIFGPVVTIIRAA..N......FDEA
O06837_PSEFL/29-498.GG.........TEAPCAQG.FFVKPTIF...ANRE-KKDI--------RLLSQEVFGPVLVATPFS..D......IAEV
Q8GPZ0_PSEAI/20-479EPG.........LEFSVEDASCYLAPTLL...TG.L-TAEM--------NIMQEETFGPVACVQTVC..G......DAEA
Q7WPE0_BORBR/13-475.GGP.......GRPAGQARG.WHVPVTIL...SD.V-TPDM--------ELAQEEVFGPVLALMPYE..DGGQDGGEAQA
Q6AA40_PROAC/499-947.............VRIDEEG.RYWSPGVR...SG.I-KPGD--------PYHLTEYFGPITGIMYAP..D......LATA
P96405_MYCTU/17-478.GG........GRPEGLDNG.FFIQPTVF...AD.V-DNKM--------TIAQEEIFGPVLAIIPYD..T......EEDA
Q8ELI8_OCEIH/14-471.GGT.......K......NG.ASVEPTVL...FN.P-PKKS--------KVVCEEVFGPIVSVIPYK..N......IEEA
Q9RZE6_DEIRA/24-482.GG............QVSSG.LFFQPTVL...VD.V-APDS--------LILREETFGPVAPVTIFD..T......EEEG
AL1L1_HUMAN/430-898.GG..........NQVPRPG.FFFEPTVF...TD.V-EDHM--------FIAKEESFGPVMIISRFADGD......LDAV
ALDH5_BACSU/16-474.LGG.......F......NG.TIVEPTIL...KD.V-KPFM--------SIAKEELFGPVVSFMKFD..S......EDEA
Q97UA1_SULSO/11-474.GGNI.....IP.....GKG.YFLEPTIF...EG.V-TSDM--------RLFKEEIFGPVLSVTEAK..D......LDEA
Q92XQ0_RHIME/15-479.GGGR.....PD.LEECGTG.YFIEPTIF...AG.V-SNDM--------RIAREEVFGPVLSAIVFD..E......PEEA
O24897_HELPY/516-965.............SFVNDNP.YLMKPSIK...YG.T-KKGD--------FTHQTELFTPILSVMEAK..D......LDEA
Q18822_CAEEL/36-498.GGV......TTIQNGCENG.YFITPTVI...VG.L-HDAS--------KVMTDEIFGPVVCITPFD..T......AEEV
O49218_ORYSA/49-511.DGR......DIVVPNFENG.NFVGPTLL...AD.V-KSEM--------ECYKEEIFGPVL.LMKAE..S......LNDA
Q8KVX3_9RHOB/30-494.GG..........GRGLNSG.CYVEPTLF...TD.V-TNSM--------RVAQEEIFGPVGTVIPFD..T......AEEA
Q20352_CAEEL/214-676.GGD......RVAVHGLENG.FYLSPCIL...TG.I-TPKM--------TVYREEIFGSVLLIIPFD..T......EDEA
Q88PZ0_PSEPK/11-471.GGH......ALD....REG.WFVSPTLY...TD.V-PKDS--------RLWTEEIFGPVLCARRFA..T......EEQA
Q881E4_PSESM/24-482.GGE.......Y......EG.LFYRPTVL...SG.V-KPGM--------RAFEEEIFGPVAVVVSFS..S......DEQA
Q6HJ76_BACHK/11-470.GGN......KR......DE.RVFEPTVL...TN.V-PEHV--------SVQCQEVFGPLMTVNTFK..E......FDEA
Q95TY8_DROME/95-558.GG..........SCDDSTG.RFVDPTIV...RV.S-DPLD--------PLLCEPCCGPFLPVFVYSDDS......FSEA
Q8ZV31_PYRAE/12-467.GG.............KRAG.AYFWPTVF...VD.V-DRNF--------RIMREEVFGPIRPVVPVK..N......DDEA
Q6MQ98_BDEBA/11-457.GG..........DSGPGPG.FHMKPVMM...LD.L-PNCS--------VLQQDELQGPLFLMTPVK..Y......QHEI
Q9AH09_RHOER/16-479.GGD......QSPTGAPEQG.FYYRPTLF...SG.V-TADM--------RIAREEIFGPVLSVLPFE..G......EEEA
Q6F9F7_ACIAD/12-472.GG..........QVCDGAG.YYYPPTIL...DCSG-VSDA--------QSIHTELFGPVLSVDTFS..T......EAEA
Q70Q17_RICRI/17-471.GG..............KTVDNFIEPTII...ID.C-LDNM--------DIFRIEIFGPVVACYKFK..D......LDEV
Q92UV7_RHIME/21-480HPG..............RSG.ALLPPIVV...DR.V-PHQS--------DLVLEETFGPIIPIVRVP..D......DDDA
Y4UC_RHISN/49-507.GNY.......R......EG.SLYHPTVL...EG.T-PLTC--------RLWHEEVFAPVVMLAPFD..T......LDKG
Q6MMT9_BDEBA/20-477.DGRN.....TPAPAGLDHG.HWIGPTIM...DN.V-APNS--------EAATLEYFGPVLSIIRCR..D......ITHA
Q703Z2_THETE/51-524.GGR......VLEEGEFSKG.FYVEPAII...EG.V-APDS--------YLWKTELFLPILLVDKFD..T......LEEA
Q73Y73_MYCPA/6-480.GG..........KPMDRKG.YFYEATII...TN.T-TPDM--------RLIREEIFGPVGCVIPFD..D......EDEV
Q8FS05_COREF/26-487.GG..........RARPDLGPYFYEPTVL...TG.V-TKKM--------ELYRHEVFGPVVYVEAVA..D......LAEA
Q93P88_9BACT/17-480.GGK......KPQGKAFEKG.HWFEPTIL...TD.V-KQNM--------TIVHEESFGPILPVIKFS..E......FNEV
YF19_SCHPO/31-493.GG..........KRHGNLG.YFVEPTIL...SN.V-TEDM--------AVGKEEIFGPVLAVIKFK..T......IEEA
Q8FS49_COREF/31-498.GGAA....TAGLTGGLENG.VFIEPTVF...AD.V-TPDM--------RIAAEEIFGPVISILRYD..DS...AGVEEA
O34184_HALVO/20-485.GGST.....AD.LDGVDDS.LVVQPTVL...SG.V-TNDM--------AAARNEHFGPIAPVIPFS..D......VDEA
ALDHX_YEASX/49-508.GG.............PRENSVYLYPTLS...AT.L-TDEC--------RIMKEEVFAPIITILCVK..T......VDEA
Q9KC36_BACHD/16-473.GGR.......R......TG.AYFEPTVL...TN.V-SPSS--------RLAKEEAFAPIVIIEGVH..S......LTEA
Q721Q0_LISMF/21-482.GGG......RLTGSDYDKG.NFYKPTVL...DN.V-TREM--------DIFYEETFGPVIPLITFE..T......EDEA
Q6FDG9_ACIAD/11-475.GGQ......AMTEGEFAKG.SFYLPTII...TG.L-KNQA--------QVCQEEIFGPVLVVMKYE..H......EDDL
PUUC_ECOLI/28-489.GR..........NAGLAAA...IGPTIF...VD.V-DPNA--------SLSREEIFGPVLVVTRFT..S......EEQA
ABDH_ECOLI/11-470TGG..........EKRKGNG.YYYAPTLL...AG.A-LQDD--------AIVQKEVFGPVVSVTPFD..N......EEQV
BADH_AMAHP/16-485.GGS......RPE..HLKKG.YYVEPTII...SD.V-STSM--------QIWREEVFGPVLCQKTFG..S......EDEA
O24829_ACISP/12-482.GGGV.....PEMPEELAGG.AWVQPTIW...TG.L-PKDS--------AVITDEIFGPCVHVCPFD..T......EEEA
Q7UFE0_RHOBA/24-485.GG..........KRSGDRG.YFIEPTVF...TD.V-QDDM--------AIARDEIFGPVMSVLSFK..D......SDDI
P83849_THETH/46-512.GGKR.....LE.....GEG.YFIAPTVF...TE.V-PPKA--------RIAQEEIFGPVLSVIRVK..D......FAEA
Q73RK8_TREDE/20-482.GGN......PYSEPLLKKG.NFIPPTIF...AD.V-TPEM--------EIFQNEIFGPVACITPFD..T......EEEA
Q6L285_PICTO/9-471.GGKK.....PELSGKYKNG.YFYEPTII...EN.V-PQDS--------PLFQEEIFGPVIGAESVS..S......VDEL
Q82K12_STRAW/25-486.GG........EIPEELKDG.AYYRPTLI...AD.A-AQDS--------EIVQSEIFGPVLVVLPFD..S......DDEG
Q6G1A0_BARQU/13-473.GGT.......GLPIGMERG.YYVRPTVF...AD.V-KPNM--------RIFREEIFGPVLSILPFN..T......ENEA
Q7S5U4_NEUCR/22-482.GG........KGQLDERKG.YFVEPTVF...LD.T-PEDA--------KIMKEEIFGPVLNINTFE..T......EEEV
Q88LI4_PSEPK/30-488.GG.........EAPSDKTG.WYVRPTVY...TN.V-NNSM--------RIAREEIFGPVLVLIPFK..D......ENEA
O85031_9RALS/11-472.GG.........I....AEG.AVMPATIL...DH.V-TADM--------QIYDEETFGPITVVIRCK..S......EADA
ALDH1_BACSU/18-484.GGEK.....LE.NGKYQNG.YYVQPAIF...DN.V-TSEM--------TIAQEEIFGPVIALIKVD..S......IEEA
Q7UYE1_RHOBA/30-491.GGG.......PATVDGLNG.NYVKPTLL...AG..-SLDN--------VAAREEIFGPVAYLAKFS..D......EADA
Q74E56_GEOSL/13-471.GG.............TVAG.NCLTPAIL...SG.V-TPDM--------KVVCSEVFAPIVSVIPYE..T......FDQA
O85973_SPHAR/26-487.GGS......RSDAADLADG.NFIKPTVF...TN.V-NNSM--------RIAQEEIFGPVTSVITWS..D......EDDM
Q7WBK1_BORPA/13-471.GG........RALSRPTRG.HYFEPCLV...TG.L-DNSA--------TVCREEVFGPFACVLTAR..D......YEHA
Q6FBY4_ACIAD/20-482.LS.........AMTLPEHG.FYVRPAIL...KN.V-PAHA--------AIMKEEVFGPVLATAAYQ..S......LDEA
Q8FY44_BRUSU/28-490.GG.........EVLDLGLG.QYMGPTIL...AG.V-KADM--------AVAREEVFGPVLSVLSFD..T......VEEA
IOLA_BACSU/15-477.DGRE.....NV....SDDG.YFVGPTIF...DN.V-TTEM--------TIWKDEIFAPVLSVIRVK..N......LKEA
Q6SF25_9BACT/16-478.GG..........RAMNIPG.AFLQPTVL...AE.V-TPEM--------TIAQTEVFGPVLSVLRFR..E......DAEA
Q6BPC7_DEBHA/15-474.GSE.......TRFSDNGEN.VPVTPLII...TN.V-TSDM--------LLDSVETFGPVLSIYKYS..D......VNEL
Q828R7_STRAW/13-460.GG.........PESTEPQG.YFVSPTVF...AD.V-TPEM--------TIAKEEIFGPVLSVIRYE..D......EEEA
Q7NEN1_GLOVI/15-481.GGEP.....VR.SEELVHG.HFFEPTIL...DE.V-PPAS--------RLAREEVFGPVVVLMTVD..S......FEQA
ALDY_BACSU/15-474.EGK.......R......VG.NVLTPYVF...VG.A-DNNS--------KIAQTELFAPIATIIKAG..S......DQEA
Q47943_GLUOY/25-486.GG.........GIVDFGKG.QYIQPTLF...TD.V-KPSM--------GIARDEIFGPVLASFHFD..T......VDEA
Q75TI0_GEOSE/8-466.GGK......RMK..EL..G.YYLTPAVF...AH.V-RQDM--------RIVQEEIFGPVITVQPFE..H......DEEA
Q8TWC7_METKA/11-466.GGE.......P......EG.RLFPPTVL...AD.V-PEDA--------LVAREETFGPVLPVIRAK..D......FEEA
Q59095_ACICA/18-473.GG.............HADG.VFFQPTVL...TD.V-TANN--------SIFSEEIFGPVAVLIPFS..S......DEQA
ROCA_BACSU/45-511.GGEG.....DD.....SKG.YFIQPTIF...AD.V-DENA--------RLMQEEIFGPVVAICKAR..D......FDHM
Q7WPN3_BORBR/33-490.AG..........NAVPQRG.LYVPPTIF...TG.V-ARDG--------ALARQEVFGPVMACLPFD..T......EQEA
ALD1_STAAS/13-470.GGP.......GKPEGLEKG.YFARPTIF...IN.V-DNQM--------TIAQEEIFGPVMSVITYN..D......LDEA
O50203_XANAU/26-493.GGER.....NTFGGDLAGG.YYVKPTVF...KG..-HNKM--------RIFQEEIFGPVVSVTTFT..D......DAEA
Q6W1I3_RHISN/34-497.GG........AS.LH.RQG.HFIEPAIF...SH.C-KPQM--------SIVREEIFGPVLVTSPFD..D......LDDA
Q7VSP3_BORPE/17-482.GGE......RLEGPGYERG.YYLTPAVF...AD.V-TQQM--------RIAREEIFGPVIALIEVN..G......YEDA
Q9L124_STRCO/18-473.GGE.......I......DG.AGYRATVL...TG.L-TTDM--------PAWREEIFGPVAPVISFA..T......TEEA
Q6JHN1_9PSEU/12-470.GG........PGQVELPEGGFYFPPTVF...TD.V-DPAQ--------EIAQEEVFGPVLAAMSFG..T......VDEA
BADH_SCHPO/29-495.GG.........LPRSEQKG.YFIPPTVF...TN.V-QTHN--------KIWREEIFGPVLAVKTFH..T......NEEA
Q59702_PSEPU/20-480.EGE.......A......QG.NVLPPHVF...AD.V-TADM--------EIAREEIFGPLVGIQRAR..D......EAHA
MSC7_YEAST/104-587.GGS......RFKHPKYPQG.HYFQPTLL...VD.V-TPEM--------KIAQNEVFGPILVMMKAK..N......TDHC
Q73WS7_MYCPA/19-482GGG.........RPAGLDVG.YYVEPTIL...SG.V-EPNS--------TIAQEEVFGPVLSVLRYR..D......DDDA
GAPN_PEA/24-484..............EYKREG.NLIWPLLL...DN.V-RPDM--------RIAWEEPFGPVLPVIRIN..S......VEEG
Q6MF92_PARUW/536-989.............KQDPQNP.YLWSPGIK...LG.V-KPGN--------FTYNTELFGPVLGLVRAE..N......FDEA
Q8CN25_STAES/16-475.GG..........HQLKRHG.FFYAPTVL...DN.V-RKDD--------NVFKDEIFGPVLAITTYR..D......FEQV
O87842_STRCO/48-500RGSAA....DARFLPGQDTS.AYVQPVTL...LN.P-PRSS--------PLHHAEPFGPVDTIVLVD..T......EAEL
AL7A1_DICDI/28-492.GGN......KLDISG...G.NFVEPTVV...A..I-EHDA--------PIVKTELFVPILYIMKFK..N......LDDA
Q6CRD2_KLULA/26-495.GGLGAPEPIAND.PALANG.YYVKPTIL...AD.V-KASY--------RIAKEEIFGPVIVVGSFK..D......YKEA
Q885F4_PSESM/28-486...E......QADPIPDRPG.YYINPTVL...AG..-TNEL--------HCAQEEIFGPVVVAIAFK..D......EEDA
Q6AKR4_DESPS/50-520.GGH......ALQGEGFESG.CYVAPTLV...E..V-KSDI--------PIIKEETFAPILYLIRYS.GD......INQA

PF07368

Q9VAW6_DROME/82-298------.........PSDRVLPDATPIMV------R.DIPH--------KFLGD.GPTGIITMHIFR--T------PFEA
Q9VYG8_DROME/38-250------...........ESLKAGESPVLV------Y.DCVH--------SYLGN.GATGVVTVHTFR--T------AKEA
Q9W2S6_DROME/22-243------LTP...DDIRFQFRMSDASPVIV------C.EFDH--------SFFGGSRPSSVVTLHTFR--N------ATEL
Q8T485_DROME/35-252------.........DVADAPACASPILV------TGGVTH--------LFFPS.GPSGCTTLHTFS--S------MREV
Q9W1T5_DROME/37-260------EEFEESDTKKRYGRRMKGSPLIV------L.DFPQ--------FYFGG.KPTAIMTMSTFR--N------MNEV
Q9V9P6_DROME/64-279------........CISEVAPPMASPIFV------C.DCTH--------DKLGS.YPTGVVTFHTFR--N------NQEA
Q9VI33_DROME/97-311------.........NPKTVPENASPMLV------Y.DLSH--------RYLAD.GPTGVITLHTFR--T------MKEA

PF00815

HISX_ECOLI/17-428---------------------QYGPEHLI---IQ-TRNARE--------.LVDSITSAGSVFLGDWSPES------AGDY
HISX_BACSU/10-423---------------------TLAPEHLE---II-TQSPEA--------.LLGSIKHAGAIFLGRYSPEP------VGDY
HISX_ARCFU/2-402---------------------EFAPEHLT---VA-VKNPEE--------.WLGKVRNAGSVFLGNFSPVA------AGDY
HIS2_NEUCR/445-864---------------------KYAPEHLI---LQ-IKEAEK--------.AVDLVMNAGSVFIGAWTPES------VGDY
HISX_METTH/13-425---------------------AYAPEHLV---IM-TDSPEE--------.TLEGIRNAGSIFLGELSPVA------AGDY
HIS2_PICPA/422-837---------------------QYAPEHLI---LQ-IENAS.--------.YVDQVQHAGSVFVGAYSPES------CGDY
HISX_HAEIN/14-423---------------------EYAPEHLI---VQ-TKNARK--------.LLPYLDNAGSIFLGAYSPES------MGDY
HISX1_SYNY3/15-432---------------------DYAPEHLQ---VL-TADPLK--------.LVGKIDNAGEILLGNYTPSS------AATY
HISX_STRCO/18-434---------------------AYGAEHLE---IQ-TADAAA--------.VADRVKNAGAIFVGPWAPVS------LGDY
HISX_BRAOC/46-459---------------------LYAPEHLI---IN-VKDAEK--------.WEGLIENAGSVFIGPWTPES------VGDY
HISX_BUCAP/18-429---------------------IYAPEHLI---IQ-TKEPRL--------.ILKEILNASSIFLGPWSPES------AGDY
HIS2_KLULA/366-785---------------------QYAPEHLI---LQ-ISNAED--------.YVKDVDHAGSIFVGAYTPES------CGDY
HISX_MYCSM/24-444---------------------AYAAEHLE---IQ-TVDAPG--------.VAGR