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217  structures 19726  species 62  interactions 54797  sequences 99  architectures

Clan: PELOTA (CL0101)

Summary

Pelota - RNA ribose binding superfamily Add an annotation

The members of this clan are all involved in binding to ribose sugar of RNA[1]. Indeed, the key RNA binding residues are conserved across the different families [1]. Members of this clan form mixed alpha-helical and beta-sheet structures [1][2].

This clan contains 5 families and the total number of domains in the clan is 54797. The clan was built by RD Finn.

Literature references

  1. Anantharaman V, Koonin EV, Aravind L;, Nucleic Acids Res. 2002;30:1427-1464.: Comparative genomics and evolution of proteins involved in RNA metabolism. PUBMED:11917006 EPMC:11917006
  2. Michel G, Sauve V, Larocque R, Li Y, Matte A, Cygler M; , Structure (Camb) 2002;10:1303-1315.: The structure of the RlmB 23S rRNA methyltransferase reveals a new methyltransferase fold with a unique knot. PUBMED:12377117 EPMC:12377117

Members

This clan contains the following 5 member families:

eRF1_3 PELOTA_1 Ribosomal_L7Ae RNase_P_pop3 SpoU_sub_bind

External database links

Domain organisation

Below is a listing of the unique domain organisations or architectures from this clan. More...

Loading domain graphics...

Alignments

The table below shows the number of occurrences of each domain throughout the sequence database. More...

Pfam family Num. domains Alignment
SpoU_sub_bind (PF08032) 32594 (59.5%) View
Ribosomal_L7Ae (PF01248) 18233 (33.3%) View
eRF1_3 (PF03465) 2290 (4.2%) View
PELOTA_1 (PF15608) 1487 (2.7%) View
RNase_P_pop3 (PF08228) 193 (0.4%) View
Total: 5 Total: 54797 Clan alignment
 

Please note: Clan alignments can be very large and can cause problems for some browsers. Read the note above before viewing.

Family relationships

This diagram shows the relationships between members of this clan. More...

Species distribution

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This tree shows the occurrence of the domains in this clan across different species. More...

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Interactions

There are 62 interactions for this clan. More...

Interacting families
A B
eRF1_1 eRF1_3
eRF1_2 eRF1_3
eRF1_3 eRF1_2
eRF1_3
Fer4
GTP_EFTU_D3
Ribosomal_L11
Ribosomal_L11_N
RLI
Fibrillarin Ribosomal_L7Ae
GTP_EFTU_D3 eRF1_3
KOW Ribosomal_L7Ae
Nop Ribosomal_L7Ae
Nop10p Ribosomal_L7Ae
Ribosomal_L10 Ribosomal_L7Ae
Ribosomal_L11_N eRF1_3
Ribosomal_L7Ae
Ribosomal_L14e Ribosomal_L7Ae
Ribosomal_L15e Ribosomal_L7Ae
Ribosomal_L23 Ribosomal_L7Ae
Ribosomal_L27e Ribosomal_L7Ae
Ribosomal_L28e Ribosomal_L7Ae
Ribosomal_L32e Ribosomal_L7Ae
Ribosomal_L34e Ribosomal_L7Ae
Ribosomal_L36e Ribosomal_L7Ae
Ribosomal_L37ae Ribosomal_L7Ae
Ribosomal_L37e Ribosomal_L7Ae
Ribosomal_L39 Ribosomal_L7Ae
Ribosomal_L41 Ribosomal_L7Ae
Ribosomal_L6 Ribosomal_L7Ae
Ribosomal_L7Ae Fibrillarin
HABP4_PAI-RBP1
Nop
Ribos_L4_asso_C
Ribosomal_L1
Ribosomal_L10
Ribosomal_L15e
Ribosomal_L16
Ribosomal_L18e
Ribosomal_L24e
Ribosomal_L27e
Ribosomal_L30_N
Ribosomal_L34e
Ribosomal_L36e
Ribosomal_L37ae
Ribosomal_L37e
Ribosomal_L39
Ribosomal_L4
Ribosomal_L40e
Ribosomal_L41
Ribosomal_L6
Ribosomal_L7Ae
Ribosomal_S15
Ribosomal_S27
Ribosomal_S7
Ribosomal_S7e
SBP_bac_1
Ribosomal_S27 Ribosomal_L7Ae
S10_plectin Ribosomal_L7Ae
SBP_bac_1 Ribosomal_L7Ae
SpoU_methylase SpoU_sub_bind
SpoU_sub_bind SpoU_methylase

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between the Pfam families in this clan, the corresponding UniProt entries, and the region of the three-dimensional structures that are available for that sequence.

Loading structure mapping...