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1609  structures 2147  species 88  interactions 12842  sequences 155  architectures

Clan: KOW (CL0107)

Summary

KOW domain Add an annotation

This superfamily includes proteins involved in translation that have a KOW like SH3-fold.

This clan contains 6 families and the total number of domains in the clan is 12842. The clan was built by A Bateman.

Members

This clan contains the following 6 member families:

EFP_N KOW Ribosomal_L14e Ribosomal_L19 Ribosomal_L21e Ribosomal_L2_C

External database links

Domain organisation

Below is a listing of the unique domain organisations or architectures from this clan. More...

Loading domain graphics...

Alignments

The table below shows the number of occurrences of each domain throughout the sequence database. More...

Pfam family Num. domains Alignment
KOW (PF00467) 4544 (35.4%) View
Ribosomal_L2_C (PF03947) 2703 (21.0%) View
Ribosomal_L19 (PF01245) 2065 (16.1%) View
EFP_N (PF08207) 1972 (15.4%) View
Ribosomal_L21e (PF01157) 1048 (8.2%) View
Ribosomal_L14e (PF01929) 510 (4.0%) View
Total: 6 Total: 12842 Clan alignment
 

Please note: Clan alignments can be very large and can cause problems for some browsers. Read the note above before viewing.

Family relationships

This diagram shows the relationships between members of this clan. More...

Species distribution

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This tree shows the occurrence of the domains in this clan across different species. More...

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Interactions

There are 88 interactions for this clan. More...

Interacting families
A B
EFP_N EFP
EFP_N
eIF-5a
tRNA-synt_2
eIF-5a EFP_N
Elong-fact-P_C EFP_N
KOW CTD
KOW
NusG
NusG_II
Ribosomal_L1
Ribosomal_L14e
Ribosomal_L18A
Ribosomal_L27e
Ribosomal_L34e
Ribosomal_L36e
Ribosomal_L39
Ribosomal_L40e
Ribosomal_L7Ae
Ribosomal_S17
Spt5-NGN
SUI1
ubiquitin
NusG KOW
NusG_II KOW
Ribosomal_60s Ribosomal_L21e
Ribosomal_L1 KOW
Ribosomal_L13e Ribosomal_L2_C
Ribosomal_L14 Ribosomal_L19
Ribosomal_L14e Ribosomal_60s
Ribosomal_L11_N
Ribosomal_L18A
Ribosomal_L22e
Ribosomal_L30_N
Ribosomal_L32e
Ribosomal_L34e
Ribosomal_L4
Ribosomal_L40e
Ribosomal_L6
Ribosomal_L6e
Ribosomal_L7Ae
ubiquitin
Ribosomal_L18p Ribosomal_L21e
Ribosomal_L19 Ribosomal_L3
Ribosomal_L2 Ribosomal_L2_C
Ribosomal_L21e Peptidase_M24
Ribosomal_60s
Ribosomal_L14
Ribosomal_L18_c
Ribosomal_L18p
Ribosomal_L21e
Ribosomal_L29e
Ribosomal_L23 Ribosomal_L14e
Ribosomal_L27A Ribosomal_L2_C
Ribosomal_L28e Ribosomal_L2_C
Ribosomal_L29 KOW
Ribosomal_L29e Ribosomal_L21e
Ribosomal_L2_C Ribosomal_L30_N
Ribosomal_L36e
Ribosomal_L37ae
Ribosomal_L9_C
Ribosomal_L3 Ribosomal_L19
Ribosomal_L31e Ribosomal_L14e
Ribosomal_L21e
Ribosomal_L32e Ribosomal_L2_C
Ribosomal_L33 Ribosomal_L2_C
Ribosomal_L34 Ribosomal_L19
Ribosomal_L35Ae Ribosomal_L21e
Ribosomal_L36 Ribosomal_L2_C
Ribosomal_L37ae Ribosomal_L2_C
Ribosomal_L38e KOW
Ribosomal_L14e
Ribosomal_L39 Ribosomal_L21e
Ribosomal_L40e Ribosomal_L14e
Ribosomal_L44 Ribosomal_L14e
Ribosomal_L5_C Ribosomal_L21e
Ribosomal_L6e Ribosomal_L14e
Ribosomal_S10 KOW
Ribosomal_S18 KOW
Ribosomal_S30 KOW
Ribosomal_S4e KOW
RS4NT KOW
S4 KOW
Spt4 KOW
Spt5-NGN KOW
tRNA-synt_2 EFP_N
ubiquitin KOW
Ribosomal_L14e

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between the Pfam families in this clan, the corresponding UniProt entries, and the region of the three-dimensional structures that are available for that sequence.

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