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29  structures 17946  species 1  interaction 64846  sequences 411  architectures

Clan: GT-C (CL0111)

Summary

Glycosyl transferase GT-C superfamily Add an annotation

This is the GT-C clan that contains diverse glycosyltransferases that possess 8-13 predicted transmembrane segments [1].

This clan contains 19 families and the total number of domains in the clan is 64846. The clan was built by A Bateman.

Literature references

  1. Liu J, Mushegian A; , Protein Sci 2003;12:1418-1431.: Three monophyletic superfamilies account for the majority of the known glycosyltransferases. PUBMED:12824488 EPMC:12824488

Members

This clan contains the following 19 member families:

ALG3 Alg6_Alg8 Arabinose_trans DIE2_ALG10 DUF2029 DUF2079 DUF2142 DUF2723 EpsG Glucan_synthase Glyco_transf_22 Mannosyl_trans Mannosyl_trans2 PIG-U PMT PMT_2 PTPS_related STT3 YfhO

Domain organisation

Below is a listing of the unique domain organisations or architectures from this clan. More...

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Alignments

The table below shows the number of occurrences of each domain throughout the sequence database. More...

Pfam family Num. domains Alignment
PMT_2 (PF13231) 12962 (20.0%) View
DUF2029 (PF09594) 11864 (18.3%) View
YfhO (PF09586) 8853 (13.7%) View
PMT (PF02366) 8381 (12.9%) View
Arabinose_trans (PF04602) 5745 (8.9%) View
EpsG (PF14897) 2740 (4.2%) View
Glyco_transf_22 (PF03901) 2401 (3.7%) View
Glucan_synthase (PF02364) 1706 (2.6%) View
STT3 (PF02516) 1659 (2.6%) View
Alg6_Alg8 (PF03155) 1390 (2.1%) View
DUF2142 (PF09913) 1129 (1.7%) View
Mannosyl_trans2 (PF04188) 961 (1.5%) View
DUF2079 (PF09852) 903 (1.4%) View
DUF2723 (PF11028) 861 (1.3%) View
PIG-U (PF06728) 690 (1.1%) View
DIE2_ALG10 (PF04922) 683 (1.1%) View
Mannosyl_trans (PF05007) 663 (1.0%) View
ALG3 (PF05208) 656 (1.0%) View
PTPS_related (PF10131) 599 (0.9%) View
Total: 19 Total: 64846 Clan alignment
 

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Family relationships

This diagram shows the relationships between members of this clan. More...

Species distribution

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This tree shows the occurrence of the domains in this clan across different species. More...

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Interactions

There is 1 interaction for this clan. More...

Interacting families
A B
Arabinose_trans Arabinose_trans

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between the Pfam families in this clan, the corresponding UniProt entries, and the region of the three-dimensional structures that are available for that sequence.

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