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539  structures 8102  species 13  interactions 141567  sequences 1601  architectures

Clan: GT-B (CL0113)

Summary

Glycosyl transferase clan GT-B Add an annotation

This is the GT-B clan that contains diverse glycosyltransferases that possess a Rossmann like fold [1].

This clan contains 35 families and the total number of domains in the clan is 141567. The clan was built by A Bateman.

Literature references

  1. Liu J, Mushegian A; , Protein Sci 2003;12:1418-1431.: Three monophyletic superfamilies account for the majority of the known glycosyltransferases. PUBMED:12824488 EPMC:12824488

Members

This clan contains the following 35 member families:

Alg14 Capsule_synth DUF1205 DUF1972 DUF3492 DUF354 Epimerase_2 Glyco_tran_28_C Glyco_trans_1_2 Glyco_trans_1_3 Glyco_trans_1_4 Glyco_trans_4_2 Glyco_trans_4_3 Glyco_trans_4_4 Glyco_transf_20 Glyco_transf_28 Glyco_transf_4 Glyco_transf_41 Glyco_transf_5 Glyco_transf_56 Glyco_transf_9 Glyco_transf_90 Glycogen_syn Glycos_transf_1 Glycos_transf_N Glyphos_transf LpxB MGDG_synth Mito_fiss_Elm1 Phosphorylase PIGA PS_pyruv_trans SUA5 Sucrose_synth UDPGT

External database links

Domain organisation

Below is a listing of the unique domain organisations or architectures from this clan. More...

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Alignments

The table below shows the number of occurrences of each domain throughout the sequence database. More...

Pfam family Num. domains Alignment
Glycos_transf_1 (PF00534) 44775 (31.6%) View
Glyco_trans_4_4 (PF13579) 11449 (8.1%) View
UDPGT (PF00201) 8949 (6.3%) View
Glyco_transf_9 (PF01075) 6767 (4.8%) View
Glyco_transf_4 (PF13439) 6671 (4.7%) View
Glyco_tran_28_C (PF04101) 6284 (4.4%) View
Glyco_transf_28 (PF03033) 6160 (4.4%) View
Glyco_transf_5 (PF08323) 5560 (3.9%) View
Glyco_trans_1_4 (PF13692) 5146 (3.6%) View
Phosphorylase (PF00343) 4954 (3.5%) View
Epimerase_2 (PF02350) 4483 (3.2%) View
Glyphos_transf (PF04464) 3039 (2.1%) View
Glyco_transf_20 (PF00982) 2717 (1.9%) View
PS_pyruv_trans (PF04230) 2481 (1.8%) View
LpxB (PF02684) 2446 (1.7%) View
Glycos_transf_N (PF04413) 2390 (1.7%) View
SUA5 (PF03481) 2044 (1.4%) View
Glyco_transf_41 (PF13844) 1950 (1.4%) View
continued
Pfam family Num. domains Alignment
Glyco_trans_4_2 (PF13477) 1823 (1.3%) View
Capsule_synth (PF05159) 1766 (1.2%) View
Glyco_transf_90 (PF05686) 1264 (0.9%) View
Glyco_trans_1_2 (PF13524) 1210 (0.9%) View
Glyco_trans_1_3 (PF13528) 1194 (0.8%) View
MGDG_synth (PF06925) 972 (0.7%) View
Glycogen_syn (PF05693) 829 (0.6%) View
Glyco_transf_56 (PF07429) 636 (0.4%) View
Alg14 (PF08660) 618 (0.4%) View
Sucrose_synth (PF00862) 604 (0.4%) View
DUF1205 (PF06722) 513 (0.4%) View
DUF1972 (PF09314) 494 (0.3%) View
Mito_fiss_Elm1 (PF06258) 342 (0.2%) View
PIGA (PF08288) 340 (0.2%) View
DUF3492 (PF11997) 322 (0.2%) View
Glyco_trans_4_3 (PF12000) 208 (0.1%) View
DUF354 (PF04007) 167 (0.1%) View
Total: 35 Total: 141567 Clan alignment
 

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Family relationships

This diagram shows the relationships between members of this clan. More...

Species distribution

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This tree shows the occurrence of the domains in this clan across different species. More...

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Interactions

There are 13 interactions for this clan. More...

Interacting families
A B
Glyco_transf_5 Glycos_transf_1
SUA5 Sua5_yciO_yrdC
UDPGT UDPGT
Glyco_transf_20 Glyco_transf_20
Glycos_transf_1 Glycos_transf_1
Glyco_transf_5
Glyco_transf_9 Glyco_transf_9
Phosphorylase Phosphorylase
Epimerase_2 Epimerase_2
Glyco_transf_28 Glyco_transf_28
Glyco_tran_28_C
Glyco_tran_28_C Glyco_transf_28
Glyco_tran_28_C

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between the Pfam families in this clan, the corresponding UniProt entries, and the region of the three-dimensional structures that are available for that sequence.

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