Sequence alignment for CL0117

PF00021

LYNX1_MOUSE/59-129-----------------------CHLCKGF.--------..GGCSRP....SSCP-W------------------SSTH.
LYPD3_RAT/142-224-----------------------CYSCMGL.--------SREKCQGAMPPVVNCY-N------------------ASGRV
LY6D_HUMAN/23-93-----------------------CHVCT...--------SSSNCKHS....VVCP-A------------------SSRF.
LY6A_MOUSE/29-105-----------------------CYQCYGVP--------FETSCPSI.....TCP-Y------------------PDGV.
TX101_RAT/141-217-----------------------CPTCL...--------ALEPCSSAP..SMPCA-N------------------GTTQ.
LYPD5_MOUSE/133-212-----------------------CYACLGT.--------HPEDCSPEKSRRVQCH-Q------------------DQSA.
Q63318_RAT/29-105-----------------------CYSCIEVP--------LNANCSTA.....TCP-Y------------------SDGV.
LY6C2_MOUSE/29-102-----------------------CYECYGVP--------IETSCPAV.....TCR-A------------------SDGF.
LY6G_MOUSE/6-82-----------------------CYNCIGVP--------PETSCNTT.....TCP-F------------------SDGF.
LY6D_MOUSE/23-93-----------------------CHVCT...--------NSANCKNP....QVCP-S------------------NFYF.
PSCA_HUMAN/23-93-----------------------CYSCKAQV--------SNEDCLQV....ENCT-Q------------------LGEQ.
LYPD4_HUMAN/142-233-----------------------CPTCVGE.--------HMKDCLPNFVTTNSCP-L------------------AAST.
UPAR_HUMAN/216-294-----------------------CYSCKGN.--------STHGCSSEETFLIDCR-G------------------PMNQ.
LY6E_MOUSE/23-99-----------------------CFSCTDQK--------NNINCLWP....VSCQ-E------------------KDHY.
LY6I_MOUSE/29-105-----------------------CYQCYGVP--------FETSCPSF.....TCP-Y------------------PDGF.
LY6F_MOUSE/29-105-----------------------CYNCLGVS--------LGIACKSI.....TCP-Y------------------PDAV.
Q810N3_MOUSE/141-219-----------------------CPVCLD..--------FKGSCNTES.NHTLCP-K------------------DTK..
UPAR_RAT/27-101-----------------------CIQCE...--------SNQDCLVE.....ECA-L------------------GQDL.
UPAR_HUMAN/25-99-----------------------CMQCK...--------TNGDCRVE.....ECA-L------------------GQDL.
LY6E_CHICK/23-96-----------------------CFSCSDAS--------SNWACLTP....VKCA-E------------------NEEH.
UPAR_BOVIN/211-289-----------------------CYSCEGN.--------GAHRCSSEETFLIDCR-G------------------PMNQ.
LYPD4_MOUSE/142-233-----------------------CPSCVGK.--------HDQECLPSFVTTENCP-F------------------AASS.
UPAR_RAT/216-295-----------------------CYSCEGN.--------STFGCSYEETSLIDCR-G------------------PMNQ.
LY6H_HUMAN/28-111-----------------------CQDCTLTT--------NSSHCTPK.....QCQ-P------------------SDTV.
LY6E_HUMAN/23-99-----------------------CFSCLNQK--------SNLYCLKP....TICS-D------------------QDNY.
G3HYY3_CRIGR/2-74-----------------------..QCE...--------DSQNCLVK.....ECA-L------------------GQDL.
M0R666_RAT/5-82-----------------------CYNCTMIP--------FGNTCSST....ATCS-Y------------------PDGV.
UPAR_BOVIN/23-97-----------------------CLQCE...--------NTTSCSVE.....ECT-P------------------GQDL.

PF00087

NXLH_PSEAU/22-85------------------------LTCYKGR--------D.R..SSE-----TCR.S------------------EQEL-
NXL1_NOTSC/22-84------------------------LICYMGP--------..K..TPR-----TCP.R------------------GQNL-
TXW1_OPHHA/22-82------------------------LICFNQE--------TYRPETTT-----TCP.D------------------GEDT-
NXS1_NAJCH/1-61------------------------MECHNQQ--------SSQPPTTT-----HCS.G------------------GETN-
CX1_NAJMO/1-60------------------------LKCNQLI--------P.P..FWK-----TCP.K------------------GKNL-
NXLH_BUNMU/25-87------------------------KICHFDT--------C.RAGELK-----VCA.S------------------GEKY-
NXS2_NAJHA/1-60------------------------MICHNQQ--------SSQPPTIK-----TCP.G------------------ETN.-
TX510_DENJA/1-57------------------------RICYNHQ--------SNTPATTK-----SC...------------------VENS-
NXL1_ACAAN/1-63------------------------VICYRGY--------..N..NPQ-----TCP.P------------------GENV-
NXS1_BUNFA/1-63------------------------RICLNQQ--------Q.S..TPE-----DQPTN------------------GQ..-
NXS1_NAJAN/1-60------------------------KICYNQP--------SSQHPTTK-----ACP.G------------------EKN.-
TXW1C_HEMHA/1-60------------------------FTCFTTP--------S.D..TSE-----TCP.I------------------GNNI-
NXLB_PSETE/1-65------------------------RTCFITP--------D.V..KSK-----PCP.P------------------GQEV-
NXLB1_BUNMU/22-86------------------------KTCLKTP--------S.S..TPQ-----TCP.Q------------------GQDI-
NXS3_NAJMO/1-61------------------------LNCHNQM--------SAQPPTTT-----RCS.R------------------WETN-
NXL2_BUNFL/1-65------------------------RTCLISP--------S.S..TSQ-----TCP.K------------------GQDI-
TXW9A_NAJKA/1-63------------------------LTCLNCP--------EMFCGKFQ-----ICR.N------------------GEKI-
NXS3_NAJHA/1-60------------------------MICYKQQ--------SLQFPITT-----VCP.G------------------EKN.-
NXL1_NAJME/1-64------------------------KRCYRTP--------D.L..KSQ-----TCP.P------------------GEDL-
NXS1_DENJA/1-59------------------------RICYNHQ--------STTPATTK-----SC...------------------GENS-
CX10_NAJHA/1-60------------------------LECNQLI--------P.I..AHK-----TCP.E------------------GKNL-
NXL1_PSSEM/22-84------------------------RECYLNP--------..H..DTQ-----TCP.S------------------GQEI-
TX496_DENVI/1-59------------------------MICYSHK--------TPQNSATI-----TC...------------------EEKT-
TXM2_DENAN/22-85------------------------LTCVTTK--------SIGGVTTE-----DCP.A------------------GQNV-
NXL1_NAJOX/1-65------------------------ITCYKTP--------..IPITSE-----TCA.P------------------GQNL-
NXL1_DENJA/1-64------------------------RTCYKTY--------S.D..KSK-----TCP.R------------------GEDI-
CX2_NAJME/1-61------------------------IKCHNTL--------..LPFIYK-----TCP.E------------------GQNL-
NXSC_PSSEM/22-82------------------------RICFNHQ--------SSQPQTTK-----TCS.P------------------GESS-
CX13A_NAJHA/1-62------------------------LKCHNTQ--------..LPFIYK-----TCP.E------------------GKNL-
TX022_DENAN/1-59------------------------RICYSHK--------ASLPRATK-----TC...------------------VENS-
TXW2_NAJHH/1-60------------------------FTCFTTP--------S.D..TSE-----TCP.D------------------GQNI-
TX311_DENAN/22-80------------------------RICYSHK--------LLQAKTTK-----TC...------------------EENS-
NXL1V_BUNMU/22-87------------------------IVCHTTA--------T.SPISAV-----TCP.P------------------GENL-
CXH_HEMHA/1-62------------------------LICHNRP--------..LPFLHK-----TCP.E------------------GQNI-
NXL4_OPHHA/1-65------------------------TKCYKTG--------DRI..ISE-----ACP.P------------------GQDL-
NXL1_NAJAC/1-64------------------------IRCFITP--------D.V..TSQ-----ACP.D------------------GQNI-
TX48_DENJA/1-59------------------------RICYTHK--------SLQAKTTK-----SC..E------------------G.NT-
TXW5_NAJNA/1-61------------------------LTCLICP--------EKYCNKVH-----TCL.N------------------GENI-
NXL1_HYDST/1-63------------------------LSCYLGY--------..K..HSQ-----TCP.P------------------GENV-
TSYL3_DENPO/1-64------------------------LTCVTSK--------SIFGITTE-----DCP.D------------------GQNL-
CXH48_ASPSC/1-63------------------------RKCFNSP--------GRL..VSK-----PCP.E------------------GNNL-
CX1_HEMHA/1-61------------------------LKCHNKL--------..VPFLSK-----TCP.E------------------GKNL-
NXL1_ASPSC/1-63------------------------RICYIAP--------..Y..DHK-----TCA.A------------------GENI-
TXAC_DENPO/1-60------------------------TICYSHT--------TTSRAILK-----DC...------------------GENS-
TXW11_NAJHH/1-64------------------------LTCLICP--------EKYCNKVH-----TCR.N------------------GENQ-
CXH32_ASPSC/1-62------------------------RKCLNTP--------..LPLFYK-----TCP.E------------------GKDL-
NXS1_ACAAN/1-61------------------------MQCCNQQ--------SSQPKTTT-----TCP.G------------------GVSS-
TXW10_NAJNI/1-64------------------------LRCLNCP--------EVFCRNFH-----TCR.N------------------GEKI-

PF02988

Q9PU34_9SAUR/20-103---------------------HSCEICHNFG--------KDCQSEEA----KECA-S------------------PEDQ-
Q9PTC5_PSETE/20-102---------------------LECDICIGLG--------RECNT.WT----KTCD-A------------------NQDA-
PLI_CRODU/20-102---------------------RSCDFCHNIG--------KDCDG.YE----EECS-S------------------PEDV-
PLIB_ELAQU/20-102---------------------IDCEHCVVWG--------QNCTG.WK----ETCG-E------------------NEDT-
PLIA_ELAQU/20-103---------------------RSCEICHNVG--------NDCGYDYV----EECH-S------------------PEDQ-

PF16975

U3IGH3_ANAPL/42-165--------------TTPFPHGFKCFTCEKAA--------DNYECNR.WAPDVYCP-R------------------GTRY-
F7E963_XENTR/52-171--------------PTPFPNSFKCFTCDKAK--------DNYLCNR.WAEDKWCP-Q------------------HTHF-
U3KHG3_FICAL/185-306--------------PTPFPNSFKCFTCDNAV--------DNYNCNR.WAEDRWCP-A------------------STRY-
LPD6B_MOUSE/58-182--------------PTPFPNSFKCFTCENAG--------DNYNCNR.WAEDKWCP-Q------------------DTQY-
F7GBQ8_MONDO/39-160--------------PTPFPNSFKCFTCENAA--------DNYNCNR.WAEDKWCP-Q------------------NTQY-
M3XHD6_LATCH/2-124--------------.TPFLYSFKCFTCDSAP--------DNYNCNR.WAEDKWCP-Q------------------DTDY-
F7CHM5_ORNAN/40-162--------------TTPYPGGFKCFTCEKAA--------DNYDCNR.WAPDVYCP-R------------------EARY-
F1R757_DANRE/34-154--------------ATPYPKSFKCFTCEQAS--------DNYSCNR.WAEDVWCP-Q------------------NTQY-
F7FWP8_MACMU/40-164--------------TTPYPGGFKCFTCEKAA--------DNYECNR.WAPDIYCP-R------------------ETRY-
A8WGG8_XENTR/40-164--------------TTPYPGGFKCFTCEKAA--------DNYDCNR.WAPDIFCP-R------------------ETRY-
R4GHW2_CHICK/40-161--------------PTPFPNSFKCFTCDNAV--------DNYNCNR.WAEDRWCP-E------------------STQY-
M4A0F0_XIPMA/40-159--------------TTPHPGGFKCFTCQDAA--------DNYNCNKSFLPD....-.------------------.TSY-
H9G7P9_ANOCA/40-164--------------TTPYPGGFKCFTCEQAV--------DNYECNQ.WAPDIYCP-R------------------VTRY-
H9G7N5_ANOCA/44-165--------------PTPYPSSFKCFTCDNVV--------DNYNCNR.WAEDKWCP-Q------------------NTQY-
H3AJQ0_LATCH/40-163--------------TTPYPGGFKCFTCENAS--------DNYECNR.WAPDVYCP-R------------------GTKY-
Q66IA6_DANRE/40-161--------------TTPYPGGFKCFTCEDAP--------DNYECNR.WAPDLYCP-R------------------ESRY-
I3K1X6_ORENI/40-160--------------TTPYPGGFKCFTCQDAV--------DNYDCNR.WAPDVYCP-K------------------DTKY-
W5M046_LEPOC/2-122--------------.TPFPSSFKCFTCDRAA--------DNYDCNR.WAEDKWCP-Q------------------HTQY-
E4X645_OIKDI/28-155--------------VLPYADAFRCFTCDNAV--------DNYECNN.HAPDVFCP-A------------------ETEF-
H2LH52_ORYLA/38-162--------------TTPHPGGFKCFTCEDAP--------DNYQCNR.WAPDVFCP-K------------------GTKY-
F1S0F8_PIG/49-169--------------QTKIFSGF.CFLNYNEL--------GKYSCNE.SVRERKGG-E------------------DTQY-

PF06211

Q9DFZ0_DANRE/1-107MDRLVSLWFQLELCAMAVLLTKGEIRCYCDA--------PHCVATGY-----MCK-S------------------ELNA-
BAMBI_HUMAN/4-111HSSYIFIWLQLELCAMAVLLTKGEIRCYCDA--------AHCVATGY-----MCK-S------------------ELSA-
Q6GQM7_DANRE/4-110NSSLVSIWLQLELCAMALLLTKGEIRCYCDA--------PHCVATGY-----MCK-S------------------ELNA-

PF01064

O16623_CAEEL/77-187---------------------VSCI.CNSDK........CN..DDSFTIPSDVVL-TIPPVIKCFSQDLIEDNYCFGHY-
O16623_CAEEL/298-408---------------------VSCF.CNTDK........CN..DDSFEIPTDVVL-TVPPVMKCFEDDLNEDNYCYGHY-
ACV1C_RAT/26-100---------------------LKCV.CLL..........CD..SSN.....FTCQ-T...................EGA-
Q9D7E5_MOUSE/28-111---------------------LRCYTCSFAK.......PCD..PVP.....RECR-E...................DEV-
Q7QGF7_ANOGA/72-163---------------------LTCY.CEGH.........CPGNLQN.....GTCE-TR.................PGGS-
ACVR1_HUMAN/33-107---------------------YMCV.CEGLS........CG..NE......DHCE-....................GQQ-
BMPR2_MOUSE/32-131---------------------RLCAFKDPYQQD....LGIGESRISHENGTILCS-K...................GST-
O73801_TAKRU/34-111---------------------LRCN.CTN..........CE..KTG.....YECE-T...................DGA-
BMR1B_HUMAN/30-110---------------------LRCK.CHHH.........CPEDSVN.....NICS-T...................DGY-
Q7Q709_ANOGA/56-159---------------------NGQEFVDDYDSYDDQPEPSD..EPVFEKNVSTVA-TCS...............RTAPF-
TGFR1_RAT/30-108---------------------LQCF.CHL..........CT..KDN.....FTCE-T...................DGL-
A1Z7L9_DROME/127-204---------------------IKCH.CDT..........CK..ESN.....NICE-T...................DGF-
A8NNV7_BRUMA/93-183---------------------..CY.CNYAPE......FCG.GFTN.....FTCI-KH.................LEAS-
F6SCX5_CIOIN/3-89---------------------LTCY.CGGSREN....PYCE..RNV.....FNCT-V..................PEGV-
F6VNM6_XENTR/11-99---------------------.ECIYYNANW.......ELE..KTNQS.GVESCE-GEK...............DKRLH-
K1QDS8_CRAGI/31-113---------------------LKCR.CSP..........CHPNAVN.....DTCI-A...................KFQ-
K1RCS7_CRAGI/7-89---------------------LKCY.CEE..........CT..DRN.....QTCE-T...................TGL-
Q24468_DROME/35-126---------------------.ECEHFDEKM........CN..TT......QQCE-TRIEHC........KMEADKFPS-
Q7QJY6_ANOGA/58-155---------------------YKCYSCEPPD........CA..DTAI..HAHYCQ-N...................AIQ-
Q95SI0_DROME/15-104---------------------LTCY.CDGS.........CP..DNVS...NGTCE-TR.................PGGS-

PF00021

LYNX1_MOUSE/59-129...CVII------ATRSPISF..TDLPL-VTKMCY..SGC...........P-------------D--VSSLGLGPHVSI
LYPD3_RAT/142-224YKGCFDG------NVTLTAAN..VTVSL-PVRGCVQDEAC...........T-------------R--DGVTGPGFTLSG
LY6D_HUMAN/23-93...CKTT------NTVEP.....LRGNL-VKKDCA..ESC........TPSY-------------T--LQGQVSSGTSST
LY6A_MOUSE/29-105...CVTQ------EAAVIVDS..QTRKV-KNNLCL..PICP.......PNIE-------------S--MEILGTKVNVKT
TX101_RAT/141-217...CYHG------KIELSGGG..MDSVV-HVKGCTTAIGC.........RLM-------------A--KMESVGPMTVKE
LYPD5_MOUSE/133-212...CFQG------NGRMNIGN..FSVPV-YIRTCHR.PSC.........TTM-------------G--TTSPWTSIDLQG
Q63318_RAT/29-105...CVSQ------VLEAVEGS..VRRTA-KSNLCL..PICP.......KFPQ-------------R--TEILGTVVYTKV
LY6C2_MOUSE/29-102...CIAQ------NIELIEDS..QRRKL-KTRQCL..SFCP.......AGVP-------------.--..IKDPNIRERT
LY6G_MOUSE/6-82...CVAL------EIEVIVDS..HRSKV-KSNLCL..PICP.......TTLD-------------N--TEITGNAVNVKT
LY6D_MOUSE/23-93...CKTV------TSVEP.....LNGNL-VRKECA..NSC........TSDY-------------S--QQGHVSSGSEVT
PSCA_HUMAN/23-93...CWTA------RIRAV.....GLLTV-ISKGCS..LNC...........V-------------D--DSQDYYVGKKNI
LYPD4_HUMAN/142-233...CYSS------TLKFQAGF..LNTTF-LLMGCAREHNQ..........LL-------------A--DFHHIGSIKVTE
UPAR_HUMAN/216-294...CLVA------TGTHEPKN....QSY-MVRGCATASMCQ.......HAHL-------------G--DAFSMNHID..V
LY6E_MOUSE/23-99...CITL------SAAAGFGN.VNLGYT-LNKGCS..PIC.........PSE-------------N--VNLNLGVASVNS
LY6I_MOUSE/29-105...CVAQ------EEEFIANS..QRKKV-KSRSCH..PFCP.......DEIE-------------K--KFILDPNTKMNI
LY6F_MOUSE/29-105...CISQ------QVELIVDS..QRRKV-KNKLCF..PFCP.......ANLE-------------N--MEILGTTVNVNT
Q810N3_MOUSE/141-219...CYAA------SLGVHGGD..LSAIF-SISGCLNSSHT.........YLL-------------N--NQNTIGIISIKE
UPAR_RAT/27-101...CRTT------VLREWEDA..EELEV-VTRGCAHKEKT........NRTM-------------S--YRMGSVIVSLTE
UPAR_HUMAN/25-99...CRTT------IVRLWEEG..EELEL-VEKSCTHSEKT........NRTL-------------S--YRTGLKITSLTE
LY6E_CHICK/23-96...CVTT------YVGVGIGG..KSGQS-ISKGCS..PVC...........P-------------S--AGINLGIAAASV
UPAR_BOVIN/211-289...CLEA------TGTKGLRN....PSY-TIRGCAAPSWCQ.......SLHV-------------A--EAFDLTHVN..V
LYPD4_MOUSE/142-233...CYSS------TLKFQAGN..LNTTF-LIMGCARDSHK..........LL-------------A--DFQHIGSIRVTE
UPAR_RAT/216-295...CLEA------TGLDVLGN....RSY-TVRGCATASWCQ.......GSHV-------------A--DSFQ.THVNLSI
LY6H_HUMAN/28-111...CASV------RITDPSSS..RKDHS-VNKMCA..SSCDFVKRHFFSDYL-------------M--GFINSGILKVDV
LY6E_HUMAN/23-99...CVTV------SASAGIGNLVTFGHS-LSKTCS..PAC.........PIP-------------E--.GVNVGVASMGI
G3HYY3_CRIGR/2-74...CRTT------VLHEWEDD..NELEL-EMRDCAHYEKT........NRTM-------------S--YRVNSKIISLAE
M0R666_RAT/5-82...CAIQ------VAEVVMGS..VRLKV-KDHICL..PVCP.......TSSQ-------------T--AEILGTVVDMKI
UPAR_BOVIN/23-97...CRTT------VLSVWEGG..NEMNV-VRKGCTHPDKT........NRSM-------------S--YRAADQIITLSE

PF00087

NXLH_PSEAU/22-85---CCTK......TW.CDQWCQ.DRGPR.LEMGCT--ATC------------------------------PRRMP.GLDF
NXL1_NOTSC/22-84---CYTK......TW.CDAFCS.SRGKV.VELGCA--ATC------------------------------PIAKS.YEDV
TXW1_OPHHA/22-82---CYST......FW.ND...H..HGVK.IERGCG--..C------------------------------PRVNP.PISI
NXS1_NAJCH/1-61---CYEK......RW.HD...H..RGTI.IERGCG--..C------------------------------PTVKP.GVKL
CX1_NAJMO/1-60---CY.K......MT.MR...A.APMVP.VKRGCI--DVC------------------------------P.KSSLLIKY
NXLH_BUNMU/25-87---CFKE......SW.RE...A..RGTR.IERGCA--ATC------------------------------PKGSVYGLYV
NXS2_NAJHA/1-60---CYKK......RW.RD...H..RGTI.IERGCG--..C------------------------------PSVKK.GVGI
TX510_DENJA/1-57---CYKS......IW.AD...H..RGTI.IKRGCG--..C------------------------------PRVKS...KI
NXL1_ACAAN/1-63---CFTR......TW.CDAFCS.SRGKV.VELGCA--ATC------------------------------PIVKS.YNEV
NXS1_BUNFA/1-63---CYIKTDCQNKTW.NT...H..RGSR.TDRGCG--..C------------------------------PKVKP.GINL
NXS1_NAJAN/1-60---CYRK......QW.SD...H..RGTI.IERGCG--..C------------------------------PTVKP.GVKL
TXW1C_HEMHA/1-60---CYEK......RW.SG...H...GMQ.IEKGCV--ASC------------------------------PSFESHYKFL
NXLB_PSETE/1-65---CYTE......TW.CDGFCG.IRGKR.VELGCA--ATC------------------------------PTPKKTGIDI
NXLB1_BUNMU/22-86---CFLK......VS.CEQFC.PIRGPV.IEQGCA--ATC------------------------------PEFRSNDRSL
NXS3_NAJMO/1-61---CYKK......RW.RD...H..RGYK.TERGCG--..C------------------------------PTVKK.GIQL
NXL2_BUNFL/1-65---CFTK......AF.CDRWCS.SRGPV.IEQGCA--ATC------------------------------PEFTSRYKSL
TXW9A_NAJKA/1-63---CFKK......LH.QR...R..PLSR.YIRGCA--DTC------------------------------PVGYP.KEMI
NXS3_NAJHA/1-60---CYKK......QW.SG...H..RGTI.IERGCG--..C------------------------------PSVKK.GIEI
NXL1_NAJME/1-64---CYTK......KW.CADWCT.SRGKV.IELGCV--ATC------------------------------PKVKP.YEQI
NXS1_DENJA/1-59---CYKK......TW.SD...H..RGTI.IERGCG--..C------------------------------PKVKQ.GIHL
CX10_NAJHA/1-60---CY.K......MF.MV...S.TSTVP.VKRGCI--DVC------------------------------P.KNSALVKY
NXL1_PSSEM/22-84---CYVK......SW.CNAWCS.SRGKV.LEFGCA--ATC------------------------------PSVNT.GTEI
TX496_DENVI/1-59---CY.K.......F.VT...K.LPGVI.LARGCG--..C------------------------------PKKEIFRKSI
TXM2_DENAN/22-85---CF.K......RWHYV...T.PKNYD.IIKGCA--ATC------------------------------PKVDN.NDPI
NXL1_NAJOX/1-65---CYTK......TW.CDAWCG.SRGKV.IELGCA--ATC------------------------------PTVES.YQDI
NXL1_DENJA/1-64---CYTK......TW.CDGFCS.QRGKR.VELGCA--ATC------------------------------PKVKT.GVEI
CX2_NAJME/1-61---CF.K......GT.LK...F.PKKTT.YNRGCA--ATC------------------------------P.KSSLLVKY
NXSC_PSSEM/22-82---CYHK......QW.SD...F..RGTI.IERGCG--..C------------------------------PTVKP.GINL
CX13A_NAJHA/1-62---CF.K......TT.LK..KL.PLKIP.IKRGCA--ATC------------------------------P.KSSALLKV
TX022_DENAN/1-59---CY.K......MF.IR...T.SPDYI.SDRGCG--..C------------------------------PTAMW.PYQT
TXW2_NAJHH/1-60---CYEK......RW.NS...H..QGVE.IK.GCV--ASC------------------------------PEFESRFRYL
TX311_DENAN/22-80---CY.K......RS.LP...K.IPLII.IGRGCG--..C------------------------------PLTLP.FLRI
NXL1V_BUNMU/22-87---CYRK......MW.CDVFCS.SRGKV.VELGCA--ATC------------------------------PSKKP.YEEV
CXH_HEMHA/1-62---CY.K......MT.LK...K.TPMKLSVKRGCA--ATC------------------------------PSERP.LVQV
NXL4_OPHHA/1-65---CYMK......TW.CDVFCG.TRGRV.IELGCT--ATC------------------------------PTVKP.HEQI
NXL1_NAJAC/1-64---CYTK......TW.CDNFCG.MRGKR.VDLGCA--ATC------------------------------PTVKP.GVDI
TX48_DENJA/1-59---CY.K......MF.IR...T.SREYI.SERGCG--..C------------------------------PTAMW.PYQT
TXW5_NAJNA/1-61---CF.K......RF.NR...I..LGKR.YDLGCA--ATC------------------------------PTVKT.GI.V
NXL1_HYDST/1-63---CFVK......TW.CDGFCN.TRGER.IIMGCA--ATC------------------------------PTAKS.GVHI
TSYL3_DENPO/1-64---CFKR......RH.YV...V.PKIYD.ITRGCV--ATC------------------------------PIPEN.YDSI
CXH48_ASPSC/1-63---CY.K......MS.NR..MY.PPGFN.VRRGCA--ETC------------------------------PRRNR.LLEV
CX1_HEMHA/1-61---CY.K......MT.ML...K.MPKIP.IKRGCT--DAC------------------------------P.KSSLLVKV
NXL1_ASPSC/1-63---CYLK......AW.CDAWCS.SRGKK.LEFGCA--ATC------------------------------PTVKP.GVDI
TXAC_DENPO/1-60---CY.R......KS.RR...H.PPKMV.LGRGCG--..C------------------------------PPGDD.YLEV
TXW11_NAJHH/1-64---CF.K......RF.NE..RK.LLGKR.YTRGCA--ATC------------------------------PEAKP.REIV
CXH32_ASPSC/1-62---CY.K......MN.FK..LL.PKKLS.IKRGCT--DTC------------------------------P.KSSLLVKV
NXS1_ACAAN/1-61---CYKK......TW.RD...H..RGTI.IERGCG--..C------------------------------PRVKP.GIRL
TXW10_NAJNI/1-64---CF.K......RFDQR...K.LLGKR.YTRGCA--VTC------------------------------PVAKP.REIV

PF02988

Q9PU34_9SAUR/20-103---CG--------TVLMEVSSAPISFRT-IHRNCFSSSLC------KLERFD-------------I--NIGHDSYLRGRI
Q9PTC5_PSETE/20-102---CV--------TFQTEVIRAPVSLSL-ISKSCGTSDTC------HLNYLE-------------T--SPHNELTVKTKR
PLI_CRODU/20-102---CG--------KVLLEISSASLSVRT-VHKNCFSSSIC------KLGQFD-------------V--NIGHHSYIRGRI
PLIB_ELAQU/20-102---CV--------TYQTEVIRPPLSITF-TAKTCGTSDTC------HLDYVE-------------A--NPHTELTLRAKR
PLIA_ELAQU/20-103---CG--------KVLLEISSAPLSIRS-SHRNCFSSSLC------KLEHFD-------------V--NTGQETYLRGRI

PF16975

U3IGH3_ANAPL/42-165---CFSQ------HMMKV-----TGESVSVTKRCVPLEDC------L..STG-------------C..TYVKHEEYKVCT
F7E963_XENTR/52-171---CKTV------HHFNS-----QGKSTSVTKKCATREEC------H..AVG-------------C..HHRLDSGHMECV
U3KHG3_FICAL/185-306---CLTA------HLFTA-----RGQSTSVTKKCATGEEC------H..LVG-------------C..HRHGDSGHTERV
LPD6B_MOUSE/58-182---CLTV------HHFTS-----HGRSTSITKKCASKNEC------H..FVG-------------C..RHSRDSEHTECR
F7GBQ8_MONDO/39-160---CLTV------HHFTS-----HGSSTSITKKCASKSEC------H..FVG-------------C..HHHQDGGQTECR
M3XHD6_LATCH/2-124---CLTI------HHFTS-----HGKSKSVTKRCAKKEEC------H..FVG-------------CHHHHHRDFGHTECT
F7CHM5_ORNAN/40-162---CYTQ------HTMAA-----SGNSVSVTKRCVALEDC------L..STG-------------C..VDLEVEGHKVSS
F1R757_DANRE/34-154---CMTI------HHFNH-----HGKTKFVTKRCAVRDEC------R..LAG-------------C..RHHKNT.HHECV
F7FWP8_MACMU/40-164---CYTQ------HTMEV-----TGNSISVTKRCVPLEEC------L..STG-------------C..RDSEHEGHKVCT
A8WGG8_XENTR/40-164---CYTQ------HIMNA-----TGESVSVTKRCAALEHC------L..NSG-------------C..RDSINKDQKVCT
R4GHW2_CHICK/40-161---CLTV------HLFTD-----HGKSTSVTKKCATGDEC------H..FVG-------------C..HHHRESGHTECV
M4A0F0_XIPMA/40-159---CYTL------HMMDN-----HGDSVSVTKRCATLEHC------R..FAG-------------C..VNITHNGFQVCT
H9G7P9_ANOCA/40-164---CYTQ------HTLEA-----NGKSVSVTKRCVPLEDC------L..ATG-------------C..IDLQHKGLRVCT
H9G7N5_ANOCA/44-165---CLTV------HHFTS-----HGRSTSVTKKCATREEC------H..FVG-------------C..RHRKETSHTECI
H3AJQ0_LATCH/40-163---CYTQ------HRMDS-----NGMSISVTKQCMSLEGC------M..STG-------------C..SETKLEGHKVCT
Q66IA6_DANRE/40-161---CYTH------HKMSW-----DGNTVSVTKRCVPLEDC------L..QTG-------------C..SDIDHEGNRVCT
I3K1X6_ORENI/40-160---CSTL------HMMDR-----SGESVSVTKRCATMEEC------L..FTG-------------C..ADVADTGYQVCS
W5M046_LEPOC/2-122---CLTV------HHFGS-----RGRSRWVTKKCAAREEC------Q..AVG-------------C..RHHTSTGHTECV
E4X645_OIKDI/28-155---CFTE------HVFKE-----ETDSIRVRKSCMTRNKC------HEQELG-------------C..QTDPISGHTTCK
H2LH52_ORYLA/38-162---CYTL------HMMDD-----NGSSVSVTKRCATLENC------Q..LTG-------------C..VNVTRTGYQMCT
F1S0F8_PIG/49-169---CLTV------HHFTS-----HGRSTFITKKCASRSEC------H..FVG-------------C..HHSQDSEHTECR

PF06211

Q9DFZ0_DANRE/1-107---CFTK------VLDPL-----NTNSP-LTHGCVDSLLN------SADVCS-------------SKNVDISSGSSSP.V
BAMBI_HUMAN/4-111---CFSR------LLDPQ-----NSNSP-LTHGCLDSLAS------TTDICQ-------------AKQARNHSGTTIPTL
Q6GQM7_DANRE/4-110---CFTR------TLDPQ-----STNSP-LSHGCYDPMLN------SGKTCH-------------SESTFDRIHGSAT.L

PF01064

O16623_CAEEL/77-187---CTYEQ-----EYIRNDFGDAYTSINSPSRGCSDLEYAEDLNS.PNMCRL..................L.....NGLL
O16623_CAEEL/298-408---CIYER-----DLTRNEFGDVFPRTAKPRRGCSDPNYTQDLSR.KNMCKI..................E.....NDWL
ACV1C_RAT/26-100---CWASV-----MLTNG....KEQVSK....SCVSLPELNAQ....VFCHS..................SNN...VTKT
Q9D7E5_MOUSE/28-111---CGVSV-----GTSEQKE..EEVIER...KGCLPRAQCPLLGHATYWSRS.................Y......SLRH
Q7QGF7_ANOGA/72-163---CFVSV-----EAVLDEE..TKQLVPEYSHGCMSPEQGGGL....LQCKV................GTVSPQLHGKSI
ACVR1_HUMAN/33-107---CFSSL-----SINDG....FHVYQK....GCFQVYEQGK.....MTCKT.................PPSP...GQAV
BMPR2_MOUSE/32-131---CYGLW-----EKSKGD...INLVKQ....GCWSHIGDPQECH.YEECVVT...............TTPPSIQNGTYR
O73801_TAKRU/34-111---CMAST-----YYVER....KEQHIR....ICINRDSLVPPGQ.PFYCLS..................AEG...LLNT
BMR1B_HUMAN/30-110---CFTMI-----EEDDSG...LPVVTS....GCLGLEGSD......FQCRD..................TPIPHQRRSI
Q7Q709_ANOGA/56-159---CYTLW-----TFDI.....VKNVTRVVVQGCWGSNDDQESCS.SNECVS...................TTETPTRHF
TGFR1_RAT/30-108---CFVSV-----TETTD....KVIHNS....MCIAEIDLIPRDR.PFVCAP.................SSKT...GAVT
A1Z7L9_DROME/127-204---CFTSV-----EKNSDG...SIIFSY....SCMVVKYNMQRSK.PFECLT.................SNERF.DTYRI
A8NNV7_BRUMA/93-183---CFHFT-----EEIYDKT..LKQIETMHLFGCAPLTRGSGGSY..FTCKA.................HLVAHARPKSI
F6SCX5_CIOIN/3-89---CYAMT-----EVLPISK..NILTQR....GCFRKNRLVPYNR.PFVCEP.................VNKS...NHQV
F6VNM6_XENTR/11-99---CYASW-----RNNSG.F..IELVKK....GCWLDDFNCY.DR..QECIA.................KEEN...PQVF
K1QDS8_CRAGI/31-113---CFTGL-----RLVVENGEQVEIISK....GCMSEEENSI.....LQCKG.................HLVPHRLPRTV
K1RCS7_CRAGI/7-89---CLTLR-----AYRKD.G..TIKIRY....RCIEKVDLGPLDGDVFECLT..................SNPMASISSK
Q24468_DROME/35-126---CYVLW-----SVNETTG..ILRIKM...KGCFTDMHECNQ....TECVT.................SAEPR.QGNIH
Q7QJY6_ANOGA/58-155---CWKSR-----TR.DPEG..NENVQR....GCTTEHEQLP.....LYCSQNQKPNTGDSGGPKKRHVSSTG...MYNI
Q95SI0_DROME/15-104---CFSAV-----QQLYDET..TGMYEEERTYGCMPPEDNGGF....LMCKV.................AAVPHLHGKNI

PF00021

LYNX1_MOUSE/59-129...........AC.C-QS-NLCN------------------------------------------
LYPD3_RAT/142-224...........SC.C-QG-PRCN------------------------------------------
LY6D_HUMAN/23-93...........QC.C-QE-DLCN------------------------------------------
LY6A_MOUSE/29-105...........SC.C-QE-DLCN------------------------------------------
TX101_RAT/141-217...........TC.S-YQ-SFLH------------------------------------------
LYPD5_MOUSE/133-212...........YC.C-EG-HLCN------------------------------------------
Q63318_RAT/29-105...........SC.C-NT-DLCN------------------------------------------
LY6C2_MOUSE/29-102...........SC.C-SE-DLCN------------------------------------------
LY6G_MOUSE/6-82...........YC.C-KE-DLCN------------------------------------------
LY6D_MOUSE/23-93...........QC.C-QT-DLCN------------------------------------------
PSCA_HUMAN/23-93...........TC.C-DT-DLCN------------------------------------------
LYPD4_HUMAN/142-233VLNILEKSQIVGAAS-SR-QDPA------------------------------------------
UPAR_HUMAN/216-294...........SC.C-TK-SGCN------------------------------------------
LY6E_MOUSE/23-99...........YC.C-QS-SFCN------------------------------------------
LY6I_MOUSE/29-105...........SC.C-QE-DLCN------------------------------------------
LY6F_MOUSE/29-105...........SC.C-KE-DLCN------------------------------------------
Q810N3_MOUSE/141-219...........TLES-NV-TLSS------------------------------------------
UPAR_RAT/27-101...........TV.C-AT-NLCN------------------------------------------
UPAR_HUMAN/25-99...........VV.C-GL-DLCN------------------------------------------
LY6E_CHICK/23-96...........YC.C-DS-FLCN------------------------------------------
UPAR_BOVIN/211-289...........SC.C-TG-SGCN------------------------------------------
LYPD4_MOUSE/142-233VINVLDKSEAVSAGH-CS-QGIS------------------------------------------
UPAR_RAT/216-295...........SC.C-NG-SGCN------------------------------------------
LY6H_HUMAN/28-111...........DC.C-EK-DLCN------------------------------------------
LY6E_HUMAN/23-99...........SC.C-QS-FLCN------------------------------------------
G3HYY3_CRIGR/2-74...........VV.C-AT-DVCN------------------------------------------
M0R666_RAT/5-82...........SC.C-NT-DLCN------------------------------------------
UPAR_BOVIN/23-97...........TV.C-RS-DLCN------------------------------------------

PF00087

NXLH_PSEAU/22-85-----------TC-C.TT.DNCN------------------------------------------
NXL1_NOTSC/22-84-----------TC-C.ST.DNCN------------------------------------------
TXW1_OPHHA/22-82-----------IC-C.KT.DKCN------------------------------------------
NXS1_NAJCH/1-61-----------NC-C.TT.DKCN------------------------------------------
CX1_NAJMO/1-60-----------MC-C.NT.NKCN------------------------------------------
NXLH_BUNMU/25-87-----------LC-C.TT.DDCN------------------------------------------
NXS2_NAJHA/1-60-----------YC-C.KT.NKCN------------------------------------------
TX510_DENJA/1-57-----------KC-C.KS.DNCN------------------------------------------
NXL1_ACAAN/1-63-----------KC-C.ST.DKCN------------------------------------------
NXS1_BUNFA/1-63-----------RC-C.KT.DKCN------------------------------------------
NXS1_NAJAN/1-60-----------HC-C.TT.EKCN------------------------------------------
TXW1C_HEMHA/1-60-----------LC-C.RI.ENCN------------------------------------------
NXLB_PSETE/1-65-----------QC-C.ST.DDCN------------------------------------------
NXLB1_BUNMU/22-86-----------LC-C.TT.DNCN------------------------------------------
NXS3_NAJMO/1-61-----------HC-C.TS.DNCN------------------------------------------
NXL2_BUNFL/1-65-----------LC-C.TT.DNCN------------------------------------------
TXW9A_NAJKA/1-63-----------EC-C.ST.DKCN------------------------------------------
NXS3_NAJHA/1-60-----------NC-C.TT.DKCN------------------------------------------
NXL1_NAJME/1-64-----------TC-C.ST.DNCN------------------------------------------
NXS1_DENJA/1-59-----------HC-C.QS.DKCN------------------------------------------
CX10_NAJHA/1-60-----------VC-C.NT.DRCN------------------------------------------
NXL1_PSSEM/22-84-----------KC-C.SA.DKCN------------------------------------------
TX496_DENVI/1-59-----------HC-C.RS.DKCN------------------------------------------
TXM2_DENAN/22-85-----------RC-C.GT.DKCN------------------------------------------
NXL1_NAJOX/1-65-----------KC-C.ST.DDCN------------------------------------------
NXL1_DENJA/1-64-----------KC-C.ST.DYCN------------------------------------------
CX2_NAJME/1-61-----------VC-C.NT.NKCN------------------------------------------
NXSC_PSSEM/22-82-----------SC-C.ES.EVCN------------------------------------------
CX13A_NAJHA/1-62-----------VC-C.ST.DKCN------------------------------------------
TX022_DENAN/1-59-----------AC-C.KG.DRCN------------------------------------------
TXW2_NAJHH/1-60-----------LC-C.RI.DNCN------------------------------------------
TX311_DENAN/22-80-----------KC-C.TS.DKCN------------------------------------------
NXL1V_BUNMU/22-87-----------TC-C.ST.DKCN------------------------------------------
CXH_HEMHA/1-62-----------EC-C.KT.DKCN------------------------------------------
NXL4_OPHHA/1-65-----------TC-C.ST.DNCN------------------------------------------
NXL1_NAJAC/1-64-----------KC-C.ST.DNCN------------------------------------------
TX48_DENJA/1-59-----------EC-C.KG.DRCN------------------------------------------
TXW5_NAJNA/1-61-----------QC-C.ST.DKCN------------------------------------------
NXL1_HYDST/1-63-----------AC-C.ST.DNCN------------------------------------------
TSYL3_DENPO/1-64-----------HC-C.KT.EKCN------------------------------------------
CXH48_ASPSC/1-63-----------VC-CCDT.DNCN------------------------------------------
CX1_HEMHA/1-61-----------VC-C.NK.DKCN------------------------------------------
NXL1_ASPSC/1-63-----------SC-C.DT.DNCN------------------------------------------
TXAC_DENPO/1-60-----------KC-C.TSPDKCN------------------------------------------
TXW11_NAJHH/1-64-----------EC-C.TT.DRCN------------------------------------------
CXH32_ASPSC/1-62-----------VC-C.DT.DKCN------------------------------------------
NXS1_ACAAN/1-61-----------IC-C.KT.DECN------------------------------------------
TXW10_NAJNI/1-64-----------EC-C.ST.DGCN------------------------------------------

PF02988

Q9PU34_9SAUR/20-103-----------HC-C-DE-ARCEA-----------------------------------------
Q9PTC5_PSETE/20-102-----------TC-C-TG-EECKT-----------------------------------------
PLI_CRODU/20-102-----------NC-C-EK-ELCED-----------------------------------------
PLIB_ELAQU/20-102-----------AC-C-TG-DECQT-----------------------------------------
PLIA_ELAQU/20-103-----------HC-C-DE-KKCEG-----------------------------------------

PF16975

U3IGH3_ANAPL/42-165-----------SC-C-EG-SICNLPLPRNTTDAV...FTTLSP...LSSTKGLSCPVTLTAACL.
F7E963_XENTR/52-171-----------SC-C-DG-MICNVEVPTNHTNAV...FSVMKSY..RKSDACRTASYSI......
U3KHG3_FICAL/185-306-----------SC-C-EG-MICNVQIPTNATNAV...LAVLQA...RRAAGGGRALPS...LALL
LPD6B_MOUSE/58-182-----------SC-C-EG-MICNVELPTNHTNAV...FAVMHA...QRTSGSSVSSVPSPYLLVL
F7GBQ8_MONDO/39-160-----------SC-C-EG-MICNVEVPTNNTNAV...FAVIQA...RRSSGTIPWTFS...LPVL
M3XHD6_LATCH/2-124-----------SC-C-EG-MICNVDVPTNHTNAV...FAVIQS...GRAPSTSKRTLS...FTAL
F7CHM5_ORNAN/40-162-----------SA-L-XG-NICNC....DASQRVGRHFATTSP...IGRTGRQGHGLALI.SCLC
F1R757_DANRE/34-154-----------SC-C-EG-MVCNVELPTNHSNAV...FAQRRA...HSSASATFRSWH...SVIL
F7FWP8_MACMU/40-164-----------SC-C-EG-NICNLPLPRNETDAT...FATTSP...INQTNRHPRCMSVIVSCLW
A8WGG8_XENTR/40-164-----------SC-C-EG-NICNLPLPRNETDAI...FATTSP...LSSSGRSAVQGGTVLACLF
R4GHW2_CHICK/40-161-----------SC-C-EG-MICNVEIPTNHTNAV...FAVLHA...RRTSGGSRRTVS...IAVL
M4A0F0_XIPMA/40-159-----------SC-C-HG-NICNVLVPRNDSGAV...FSSAGP...LVGAGSTPRPAALRYITLI
H9G7P9_ANOCA/40-164-----------SC-C-EG-NICNLPLPRNASDAI...FATTTP...LNHTQRHLQSASIMMLFLL
H9G7N5_ANOCA/44-165-----------SC-C-EG-MICNVDIPTNQTNAV...FAVVHT...RRTSGGSRQTIS...TLLL
H3AJQ0_LATCH/40-163-----------SC-C-EG-NICNLPLPWNASDAI...FATISP...INKATRHLHHIPITLTCT.
Q66IA6_DANRE/40-161-----------AC-C-EG-NICNLPLPRNETDAI...FSTTSP...INRSAQSTQTLPLLLL...
I3K1X6_ORENI/40-160-----------SC-C-EG-NICNVLVPRNDSSAI...FSSISP...LVSLSGSLHSRALCY....
W5M046_LEPOC/2-122-----------SC-C-EG-MACNVEVPTNRTNAV...FAMMKS...RGSSAPSVRTWS...SASL
E4X645_OIKDI/28-155-----------EC-C-QG-EICNLPVPKTNER.....FEEMLAEIGLNSAKNQFLSIAGLLFTTV
H2LH52_ORYLA/38-162-----------SC-C-EG-NICNIMVPRNDSSAI...FSSTSP...LVSSGRGLHPAGLIFFIIV
F1S0F8_PIG/49-169-----------SC-C-EG-MICNVELPTNNTNAV...FAVMHA...QRMSGSSAPSLY...LPAL

PF06211

Q9DFZ0_DANRE/1-107-----------EC-C-HD-DMCNYRGLHD------------------------------------
BAMBI_HUMAN/4-111-----------EC-C-HE-DMCNYRGLHD------------------------------------
Q6GQM7_DANRE/4-110-----------QC-C-HE-DMCNYRGLQD------------------------------------

PF01064

O16623_CAEEL/77-187-----------EC-QCST-PYCNRDQPFEV-----------------------------------
O16623_CAEEL/298-408-----------QC-ICDT-EFCNREQNIEV-----------------------------------
ACV1C_RAT/26-100-----------EC-CF.T-DFCNNITQHLP-----------------------------------
Q9D7E5_MOUSE/28-111-----------QC-CE.Q-DLCNAAASQPP-----------------------------------
Q7QGF7_ANOGA/72-163-----------VC-CDNE-DLCNQDLQPPY-----------------------------------
ACVR1_HUMAN/33-107-----------EC-CQ.G-DWCNRNITAQL-----------------------------------
BMPR2_MOUSE/32-131-----------FC-CCST-DLCNVNFTENF-----------------------------------
O73801_TAKRU/34-111-----------HC-CY.E-DYCNSIDLKVP-----------------------------------
BMR1B_HUMAN/30-110-----------EC-CTER-NECNKDLHPTL-----------------------------------
Q7Q709_ANOGA/56-159-----------FC-CCSG-DNCNGNFSYLP-----------------------------------
TGFR1_RAT/30-108-----------YC-CN.Q-DHCNKIELPTT-----------------------------------
A1Z7L9_DROME/127-204-----------DC-CK.S-DFCNKNE....-----------------------------------
A8NNV7_BRUMA/93-183-----------AC-CQEG-NYCNRNLSV..-----------------------------------
F6SCX5_CIOIN/3-89-----------IC-CK.T-DFCNHPEAME.-----------------------------------
F6VNM6_XENTR/11-99-----------FC-CCEG-NYCNKKFTHL.-----------------------------------
K1QDS8_CRAGI/31-113-----------EC-CNDE-DYCNDFLDP..-----------------------------------
K1RCS7_CRAGI/7-89-----------LC-CNDE-DFCNKHLFPT.-----------------------------------
Q24468_DROME/35-126-----------FC-CCKG-SRCNSNQKY..-----------------------------------
Q7QJY6_ANOGA/58-155-----------EC-CT.G-DYCNNGSFPE.-----------------------------------
Q95SI0_DROME/15-104-----------VC-CDKE-DFCNRDLYPT.-----------------------------------

This alignment is coloured according to the ClustalX colouring scheme:

 
Glycine (G)
 
Proline (P)
 
Small or hydrophobic (C,A,V,L,I,M,F,W)
 
Hydroxyl or amine amino acids (S,T,N,Q)
 
Charged amino-acids (D,E,R,K)
 
Histidine or tyrosine (H,Y)

For UniProt-based alignments, we also add some additional mark-up to the alignments where appropriate. Active site information is shown as follows:

 
Active site (residue annotated in SwissProt as an active site)
 
Predicted active site (residue aligns in a Pfam alignment with a SwissProt active site)
 
Predicted active site (residue annotated in SwissProt as a potential active site)

Some UniProt sequences can be mapped to protein structures, in which case we also show the secondary structure definition. These lines are shown below the sequence to which they apply and are marked (SS). The meaning of each of the symbols is as follows:

C
Random coil
H
Alpha-helix
G
3(10) helix
I
Pi-helix
E
Hydrogen bonded beta-strand (extended strand)
B
Residue in isolated beta-bridge
T
H-bonded turn (3-turn, 4-turn, or 5-turn)
S
Bend (five-residue bend centered at residue i)
Close window