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3737  structures 27573  species 261  interactions 4270183  sequences 8240  architectures

Clan: HTH (CL0123)

Summary

Helix-turn-helix clan Add an annotation

This family contains a diverse range of mostly DNA-binding domains that contain a helix-turn-helix motif.

This clan contains 217 families and the total number of domains in the clan is 4270183. The clan was built by A Bateman.

Literature references

  1. Brennan RG, Matthews BW; , J Biol Chem 1989;264:1903-1906.: The helix-turn-helix DNA binding motif. PUBMED:2644244 EPMC:2644244
  2. Brennan RG; , Cell 1993;74:773-776.: The winged-helix DNA-binding motif: another helix-turn-helix takeoff. PUBMED:8374950 EPMC:8374950
  3. Wintjens R, Rooman M; , J Mol Biol 1996;262:294-313.: Structural classification of HTH DNA-binding domains and protein-DNA interaction modes. PUBMED:8831795 EPMC:8831795

Members

This clan contains the following 217 member families:

AphA_like Arg_repressor ARID B-block_TFIIIC Bac_DnaA_C BetR Bot1p BrkDBD CENP-B_N Cro Crp CSN8_PSD8_EIF3K DDRGK Dimerisation Dimerisation2 DsrD DUF1133 DUF1153 DUF1323 DUF134 DUF1441 DUF1492 DUF1495 DUF1670 DUF1804 DUF1836 DUF1870 DUF2089 DUF2250 DUF2316 DUF2582 DUF3116 DUF3853 DUF387 DUF3908 DUF4364 DUF739 DUF742 DUF977 E2F_TDP Ets Exc F-112 FaeA Fe_dep_repr_C Fe_dep_repress FeoC Ftsk_gamma FUR GcrA GerE GntR HARE-HTH HemN_C Homeobox Homeobox_KN Homez HrcA_DNA-bdg HSF_DNA-bind HTH_1 HTH_10 HTH_11 HTH_12 HTH_13 HTH_15 HTH_16 HTH_17 HTH_18 HTH_19 HTH_20 HTH_21 HTH_22 HTH_23 HTH_24 HTH_25 HTH_26 HTH_27 HTH_28 HTH_29 HTH_3 HTH_30 HTH_31 HTH_32 HTH_33 HTH_34 HTH_35 HTH_36 HTH_37 HTH_38 HTH_39 HTH_40 HTH_41 HTH_42 HTH_43 HTH_45 HTH_46 HTH_47 HTH_5 HTH_6 HTH_7 HTH_8 HTH_9 HTH_AraC HTH_AsnC-type HTH_CodY HTH_Crp_2 HTH_DeoR HTH_IclR HTH_Mga HTH_micro HTH_OrfB_IS605 HTH_psq HTH_Tnp_1 HTH_Tnp_1_2 HTH_Tnp_4 HTH_Tnp_IS1 HTH_Tnp_IS630 HTH_Tnp_ISL3 HTH_Tnp_Mu_1 HTH_Tnp_Mu_2 HTH_Tnp_Tc3_1 HTH_Tnp_Tc3_2 HTH_Tnp_Tc5 HTH_WhiA HxlR IF2_N KORA KorB LacI LexA_DNA_bind LZ_Tnp_IS481 MADF_DNA_bdg MarR MarR_2 MerR MerR-DNA-bind MerR_1 MerR_2 Mga Mnd1 Mor MotA_activ MqsA_antitoxin MRP-L20 Myb_DNA-bind_2 Myb_DNA-bind_3 Myb_DNA-bind_4 Myb_DNA-bind_5 Myb_DNA-bind_6 Myb_DNA-bind_7 Myb_DNA-binding Neugrin NUMOD1 OST-HTH P22_Cro PaaX PadR PAX PCI Penicillinase_R Phage_AlpA Phage_antitermQ Phage_CI_repr Phage_CII Phage_rep_org_N Phage_terminase Pou Pox_D5 PuR_N Put_DNA-bind_N Rap1-DNA-bind Rep_3 RepA_C RepA_N RepC RepL Replic_Relax RFX_DNA_binding Ribosomal_S19e Ribosomal_S25 Rio2_N RNA_pol_Rpc34 RP-C RPA RPA_C RQC Rrf2 RTP RuvB_C SAC3_GANP SANT_DAMP1_like SatD SgrR_N Sigma54_CBD Sigma54_DBD Sigma70_ECF Sigma70_r2 Sigma70_r3 Sigma70_r4 Sigma70_r4_2 SLIDE SpoIIID Sulfolobus_pRN TBPIP Terminase_5 TetR_N TFIIE_alpha Tn916-Xis TraI_2_C Trans_reg_C TrfA TrmB Trp_repressor UPF0122 YdaS_antitoxin YokU z-alpha

External database links

Domain organisation

Below is a listing of the unique domain organisations or architectures from this clan. More...

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Alignments

The table below shows the number of occurrences of each domain throughout the sequence database. More...

Pfam family Num. domains Alignment
HTH_1 (PF00126) 401538 (9.4%) View
TetR_N (PF00440) 328784 (7.7%) View
HTH_18 (PF12833) 267537 (6.3%) View
Trans_reg_C (PF00486) 239488 (5.6%) View
GntR (PF00392) 231015 (5.4%) View
HTH_3 (PF01381) 167775 (3.9%) View
GerE (PF00196) 164479 (3.9%) View
Sigma70_r2 (PF04542) 148218 (3.5%) View
LacI (PF00356) 121955 (2.9%) View
MarR (PF01047) 107718 (2.5%) View
Sigma70_r4_2 (PF08281) 79346 (1.9%) View
MerR_1 (PF13411) 78301 (1.8%) View
HTH_DeoR (PF08220) 72424 (1.7%) View
HTH_8 (PF02954) 69331 (1.6%) View
Sigma70_r4 (PF04545) 66494 (1.6%) View
HTH_19 (PF12844) 61967 (1.5%) View
HTH_11 (PF08279) 61454 (1.4%) View
HTH_24 (PF13412) 61248 (1.4%) View
HTH_Tnp_1 (PF01527) 58544 (1.4%) View
HTH_5 (PF01022) 55682 (1.3%) View
HTH_6 (PF01418) 51799 (1.2%) View
HTH_IclR (PF09339) 51173 (1.2%) View
Sigma70_r3 (PF04539) 43955 (1.0%) View
MarR_2 (PF12802) 43846 (1.0%) View
FUR (PF01475) 43518 (1.0%) View
HTH_21 (PF13276) 41233 (1.0%) View
Mga (PF05043) 37982 (0.9%) View
HxlR (PF01638) 36146 (0.8%) View
Homeobox (PF00046) 35751 (0.8%) View
Rrf2 (PF02082) 33968 (0.8%) View
PadR (PF03551) 33404 (0.8%) View
IF2_N (PF04760) 33385 (0.8%) View
HTH_17 (PF12728) 29488 (0.7%) View
HTH_Crp_2 (PF13545) 28569 (0.7%) View
Myb_DNA-binding (PF00249) 28131 (0.7%) View
HTH_30 (PF13556) 27510 (0.6%) View
HTH_20 (PF12840) 26921 (0.6%) View
Ftsk_gamma (PF09397) 24387 (0.6%) View
Arg_repressor (PF01316) 23981 (0.6%) View
HTH_31 (PF13560) 23535 (0.6%) View
HemN_C (PF06969) 21603 (0.5%) View
Bac_DnaA_C (PF08299) 19987 (0.5%) View
HTH_28 (PF13518) 19425 (0.5%) View
HTH_7 (PF02796) 19060 (0.4%) View
RuvB_C (PF05491) 18794 (0.4%) View
HTH_OrfB_IS605 (PF12323) 18377 (0.4%) View
Penicillinase_R (PF03965) 16960 (0.4%) View
Fe_dep_repress (PF01325) 16856 (0.4%) View
Fe_dep_repr_C (PF02742) 16743 (0.4%) View
LexA_DNA_bind (PF01726) 16576 (0.4%) View
HTH_38 (PF13936) 15122 (0.4%) View
RQC (PF09382) 13888 (0.3%) View
DUF387 (PF04079) 13648 (0.3%) View
HTH_25 (PF13413) 13552 (0.3%) View
MerR (PF00376) 12738 (0.3%) View
MerR-DNA-bind (PF09278) 12518 (0.3%) View
HTH_26 (PF13443) 12400 (0.3%) View
Phage_AlpA (PF05930) 12373 (0.3%) View
HTH_23 (PF13384) 12113 (0.3%) View
Crp (PF00325) 10483 (0.2%) View
HTH_WhiA (PF02650) 10295 (0.2%) View
Sigma54_DBD (PF04552) 10117 (0.2%) View
Sigma54_CBD (PF04963) 10097 (0.2%) View
Trp_repressor (PF01371) 9281 (0.2%) View
PCI (PF01399) 9041 (0.2%) View
Put_DNA-bind_N (PF06971) 8979 (0.2%) View
SgrR_N (PF12793) 8700 (0.2%) View
HTH_Tnp_ISL3 (PF13542) 8470 (0.2%) View
HTH_AsnC-type (PF13404) 7917 (0.2%) View
UPF0122 (PF04297) 7834 (0.2%) View
HTH_22 (PF13309) 7707 (0.2%) View
Rep_3 (PF01051) 7683 (0.2%) View
HARE-HTH (PF05066) 7572 (0.2%) View
HTH_40 (PF14493) 7468 (0.2%) View
HTH_37 (PF13744) 7418 (0.2%) View
PuR_N (PF09182) 7105 (0.2%) View
HTH_27 (PF13463) 7070 (0.2%) View
HTH_CodY (PF08222) 7004 (0.2%) View
HTH_36 (PF13730) 6949 (0.2%) View
HTH_Tnp_IS1 (PF12759) 6577 (0.2%) View
HTH_42 (PF06224) 6267 (0.1%) View
HTH_29 (PF13551) 6187 (0.1%) View
DUF1323 (PF07037) 6022 (0.1%) View
RepA_N (PF06970) 5964 (0.1%) View
Homeobox_KN (PF05920) 5865 (0.1%) View
HTH_46 (PF15977) 5593 (0.1%) View
HTH_35 (PF13693) 5548 (0.1%) View
Myb_DNA-bind_6 (PF13921) 5464 (0.1%) View
Pox_D5 (PF03288) 4918 (0.1%) View
DUF2316 (PF10078) 4622 (0.1%) View
MerR_2 (PF13591) 4620 (0.1%) View
HTH_12 (PF08461) 4554 (0.1%) View
TrmB (PF01978) 4548 (0.1%) View
Phage_antitermQ (PF06530) 4513 (0.1%) View
PaaX (PF07848) 4454 (0.1%) View
HTH_32 (PF13565) 4152 (0.1%) View
HSF_DNA-bind (PF00447) 3951 (0.1%) View
FeoC (PF09012) 3936 (0.1%) View
DUF977 (PF06163) 3861 (0.1%) View
Mor (PF08765) 3696 (0.1%) View
Myb_DNA-bind_4 (PF13837) 3656 (0.1%) View
Terminase_5 (PF06056) 3624 (0.1%) View
HTH_Tnp_Tc5 (PF03221) 3570 (0.1%) View
LZ_Tnp_IS481 (PF13011) 3456 (0.1%) View
HTH_10 (PF04967) 3369 (0.1%) View
DUF1836 (PF08876) 3368 (0.1%) View
DUF739 (PF05339) 3321 (0.1%) View
P22_Cro (PF14549) 3294 (0.1%) View
Ets (PF00178) 3260 (0.1%) View
continued
Pfam family Num. domains Alignment
OST-HTH (PF12872) 3248 (0.1%) View
HTH_Mga (PF08280) 3195 (0.1%) View
ARID (PF01388) 3148 (0.1%) View
HTH_Tnp_4 (PF13613) 3131 (0.1%) View
HTH_16 (PF12645) 3130 (0.1%) View
Dimerisation2 (PF16864) 3021 (0.1%) View
DUF742 (PF05331) 2824 (0.1%) View
HTH_33 (PF13592) 2789 (0.1%) View
DUF1441 (PF07278) 2779 (0.1%) View
DUF1492 (PF07374) 2774 (0.1%) View
DUF1870 (PF08965) 2636 (0.1%) View
HTH_Tnp_IS630 (PF01710) 2446 (0.1%) View
Phage_CII (PF05269) 2430 (0.1%) View
HrcA_DNA-bdg (PF03444) 2409 (0.1%) View
Phage_CI_repr (PF07022) 2392 (0.1%) View
Phage_rep_org_N (PF09681) 2365 (0.1%) View
MADF_DNA_bdg (PF10545) 2362 (0.1%) View
E2F_TDP (PF02319) 2325 (0.1%) View
Exc (PF07825) 2241 (0.1%) View
HTH_psq (PF05225) 2086 (0.0%) View
PAX (PF00292) 2076 (0.0%) View
DUF1133 (PF06576) 2061 (0.0%) View
Myb_DNA-bind_3 (PF12776) 1867 (0.0%) View
HTH_Tnp_Tc3_2 (PF01498) 1799 (0.0%) View
RepL (PF05732) 1787 (0.0%) View
Tn916-Xis (PF09035) 1772 (0.0%) View
Pou (PF00157) 1761 (0.0%) View
FaeA (PF04703) 1755 (0.0%) View
Dimerisation (PF08100) 1707 (0.0%) View
HTH_41 (PF14502) 1679 (0.0%) View
CSN8_PSD8_EIF3K (PF10075) 1672 (0.0%) View
KorB (PF08535) 1663 (0.0%) View
YdaS_antitoxin (PF15943) 1598 (0.0%) View
SAC3_GANP (PF03399) 1573 (0.0%) View
Replic_Relax (PF13814) 1342 (0.0%) View
TraI_2_C (PF07515) 1323 (0.0%) View
GcrA (PF07750) 1320 (0.0%) View
Ribosomal_S19e (PF01090) 1269 (0.0%) View
SpoIIID (PF12116) 1256 (0.0%) View
RFX_DNA_binding (PF02257) 1234 (0.0%) View
HTH_Tnp_Mu_1 (PF02316) 1232 (0.0%) View
MqsA_antitoxin (PF15731) 1139 (0.0%) View
HTH_34 (PF13601) 1081 (0.0%) View
Ribosomal_S25 (PF03297) 1081 (0.0%) View
CENP-B_N (PF04218) 1074 (0.0%) View
DUF134 (PF02001) 1061 (0.0%) View
TFIIE_alpha (PF02002) 999 (0.0%) View
HTH_43 (PF09904) 995 (0.0%) View
RPA (PF10134) 969 (0.0%) View
RP-C (PF03428) 966 (0.0%) View
HTH_39 (PF14090) 943 (0.0%) View
HTH_AraC (PF00165) 921 (0.0%) View
DUF2582 (PF10771) 919 (0.0%) View
Myb_DNA-bind_5 (PF13873) 907 (0.0%) View
Rio2_N (PF09202) 850 (0.0%) View
SatD (PF16264) 845 (0.0%) View
SLIDE (PF09111) 842 (0.0%) View
RNA_pol_Rpc34 (PF05158) 829 (0.0%) View
DUF1153 (PF06627) 797 (0.0%) View
Cro (PF09048) 775 (0.0%) View
DUF4364 (PF14277) 737 (0.0%) View
NUMOD1 (PF07453) 701 (0.0%) View
Myb_DNA-bind_7 (PF15963) 672 (0.0%) View
Phage_terminase (PF10668) 667 (0.0%) View
DUF2089 (PF09862) 655 (0.0%) View
RPA_C (PF08784) 637 (0.0%) View
SANT_DAMP1_like (PF16282) 620 (0.0%) View
B-block_TFIIIC (PF04182) 600 (0.0%) View
Sigma70_ECF (PF07638) 548 (0.0%) View
Mnd1 (PF03962) 529 (0.0%) View
DUF1804 (PF08822) 525 (0.0%) View
TBPIP (PF07106) 514 (0.0%) View
BetR (PF08667) 505 (0.0%) View
HTH_9 (PF08221) 495 (0.0%) View
HTH_13 (PF11972) 492 (0.0%) View
HTH_45 (PF14947) 481 (0.0%) View
HTH_Tnp_Mu_2 (PF09039) 430 (0.0%) View
z-alpha (PF02295) 406 (0.0%) View
Neugrin (PF06413) 394 (0.0%) View
HTH_47 (PF16221) 386 (0.0%) View
HTH_Tnp_Tc3_1 (PF11427) 360 (0.0%) View
DDRGK (PF09756) 359 (0.0%) View
RepC (PF06504) 348 (0.0%) View
RepA_C (PF04796) 337 (0.0%) View
Bot1p (PF12298) 330 (0.0%) View
TrfA (PF07042) 328 (0.0%) View
YokU (PF14122) 325 (0.0%) View
KORA (PF16509) 316 (0.0%) View
HTH_15 (PF12324) 312 (0.0%) View
Myb_DNA-bind_2 (PF08914) 305 (0.0%) View
MRP-L20 (PF12824) 301 (0.0%) View
DUF3853 (PF12964) 274 (0.0%) View
DUF3116 (PF11313) 235 (0.0%) View
DUF3908 (PF13048) 226 (0.0%) View
Homez (PF11569) 217 (0.0%) View
BrkDBD (PF09607) 217 (0.0%) View
DUF2250 (PF10007) 159 (0.0%) View
RTP (PF02334) 116 (0.0%) View
DUF1670 (PF07900) 94 (0.0%) View
DsrD (PF08679) 75 (0.0%) View
DUF1495 (PF07381) 74 (0.0%) View
Rap1-DNA-bind (PF09197) 72 (0.0%) View
HTH_Tnp_1_2 (PF13022) 71 (0.0%) View
Sulfolobus_pRN (PF05584) 48 (0.0%) View
MotA_activ (PF09114) 36 (0.0%) View
AphA_like (PF14557) 29 (0.0%) View
HTH_micro (PF17007) 18 (0.0%) View
F-112 (PF09645) 4 (0.0%) View
Total: 217 Total: 4270183 Clan alignment
 

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Family relationships

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Species distribution

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Interactions

There are 261 interactions for this clan. More...

Interacting families
A B
AAA RuvB_C
Amino_oxidase Myb_DNA-binding
Arg_repressor Arg_repressor
Arg_repressor_C
Arg_repressor_C Arg_repressor
AsiA Sigma70_r4
AsnC_trans_reg HTH_24
Autoind_bind GerE
Bac_DnaA Bac_DnaA_C
BTAD Trans_reg_C
cNMP_binding Crp
HTH_Crp_2
CoA_binding Put_DNA-bind_N
CodY HTH_CodY
Couple_hipA HTH_3
Cro Cro
Crp cNMP_binding
Cupin_2 HTH_3
CUT Homeobox
DEAD RQC
Dimerisation Dimerisation
Methyltransf_2
DsrD DsrD
DUF1870 DUF1870
DUF1956 TetR_N
DUF2582 DUF2582
DUF387 DUF387
E2F_TDP E2F_TDP
Ets Ank_2
Ets
PAX
SRF-TF
Exc Exc
FCD GntR
Fe_dep_repr_C Fe_dep_repr_C
Fe_dep_repress
FeoA
Fe_dep_repress Fe_dep_repr_C
Fe_dep_repress
FeoA
FeoA Fe_dep_repr_C
FeoB_N FeoC
FHA Trans_reg_C
FlgM Sigma70_r4
Ftsk_gamma Ftsk_gamma
FUR FUR
GerE Autoind_bind
GerE
Prok-TraM
Response_reg
GntR FadR_C
FCD
GntR
UTRA
HATPase_c Sigma70_r3
HipA_C HTH_3
HNF-1_N Homeobox
Homeobox Engrail_1_C_sig
Geminin
HNF-1_N
Homeobox
PD-C2-AF1
Pou
Homeobox_KN Homeobox_KN
HSF_DNA-bind HSF_DNA-bind
HTH_1 HTH_1
LysR_substrate
HTH_11 3H
BPL_LplA_LipB
HTH_15 HTH_15
MerB
HTH_18 GyrI-like
HTH_18
RNA_pol_A_CTD
HTH_19 HTH_19
HTH_20 HTH_20
HTH_23 HTH_23
HTH_24 AsnC_trans_reg
HTH_24
HTH_26 HTH_26
HTH_27 HTH_27
HTH_3 Cupin_2
HipA_C
HTH_3
ParBc
SinI
HTH_30 HTH_30
HTH_31 HTH_31
HTH_37 HTH_37
HTH_38 HTH_38
Sugar-bind
HTH_43 HTH_43
HTH_45 HTH_45
HTH_5 HTH_5
HTH_6 HTH_6
SIS
HTH_7 HTH_7
HTH_8 HTH_8
HTH_9 RNA_pol_Rpc82
HTH_AsnC-type HTH_AsnC-type
HTH_CodY HTH_CodY
HTH_Crp_2 cNMP_binding
DUF3539
HTH_Crp_2
HTH_IclR HTH_IclR
IclR
HTH_Mga Mga
HTH_Tnp_1_2 HTH_Tnp_1_2
HTH_Tnp_Mu_1 HTH_Tnp_Mu_2
HTH_Tnp_Tc3_2 HTH_Tnp_Tc3_2
HxlR HxlR
IclR HTH_IclR
KorB ParBc
LacI Peripla_BP_1
LexA_DNA_bind LexA_DNA_bind
LysR_substrate HTH_1
MarR MarR
ROK
MarR_2 MarR_2
MBF1 HTH_3
MerB HTH_15
MerR MerR
MerR-DNA-bind
MerR-DNA-bind MerR-DNA-bind
TipAS
MerR_2 DnaJ
Methyltransf_2 Dimerisation
MotA_activ MotA_activ
MreB_Mbl HTH_25
Myb_DNA-bind_6 Myb_DNA-bind_6
OST-HTH OST-HTH
P22_Cro P22_Cro
PaaX PaaX_C
PadR PadR
Vir_act_alpha_C
ParBc HTH_3
KorB
PAS_9 GerE
PAX Ets
PCI DSS1_SEM1
MitMem_reg
PCI
Rpn3_C
SAC3_GANP
Penicillinase_R Penicillinase_R
Peripla_BP_1 LacI
Peripla_BP_3 HTH_AraC
Phage_CII Phage_CII
Pou HMG_box
Homeobox
PD-C2-AF1
Pou
Pox_D5 Pox_D5
Pribosyltran PuR_N
PuR_N Pribosyltran
PuR_N
Put_DNA-bind_N CoA_binding
Put_DNA-bind_N
Rep_3 Rep_3
Rep_fac-A_3 RPA_C
Resolvase HTH_7
Response_reg GerE
HTH_8
Trans_reg_C
RFX_DNA_binding RFXA_RFXANK_bdg
Ribosomal_S13 Ribosomal_S19e
Ribosomal_S25
Ribosomal_S19e Ribosomal_S7
Ribosomal_S9
Ribosomal_S25 EFG_C
GTP_EFTU
GTP_EFTU_D2
Ribosomal_S13
Ribosomal_S7
Ribosomal_S27 Ribosomal_S25
Ribosomal_S7 Ribosomal_S25
Ribosomal_S9 Ribosomal_S19e
Ribosomal_S25
Rio2_N RIO1
RNA_pol_A_CTD Sigma70_r4
RNA_pol_Rpb1_1 Sigma70_r2
Sigma70_r3
Sigma70_r4
RNA_pol_Rpb1_2 Sigma70_r3
RNA_pol_Rpb2_1 Sigma70_r3
RNA_pol_Rpb2_6 Sigma70_r3
Sigma70_r4
RNA_pol_Rpb2_7 Sigma70_r3
RPA_C Rep_fac-A_3
Rep_fac-A_C
RPA_C
T_Ag_DNA_bind
RPN7 PCI
RQC DEAD
Helicase_C
Rrf2 Rrf2
Rsd_AlgQ Sigma70_r4
RseA_N Sigma70_r2
Sigma70_r4_2
RTP RTP
RuvB_C RuvB_C
RuvB_N RuvB_C
SAC3_GANP DSS1_SEM1
PCI
SBP_bac_1 Homeobox
ScpA_ScpB DUF387
Sigma70_ner Sigma70_r2
Sigma70_r1_2 Sigma70_r2
Sigma70_r3
Sigma70_r2 Cupin_7
FlgM
RseA_N
Sigma70_r2
Sigma70_r3
Sigma70_r4
zf-HC2
Sigma70_r3 FlgM
Sigma70_r1_2
Sigma70_r2
Sigma70_r3
Sigma70_r4
Sigma70_r4 Cupin_7
FlgM
HTH_3
Sigma70_r2
Sigma70_r4
TFX_C
zf-HC2
Sigma70_r4_2 RseA_N
Sigma70_r4_2
SLIDE WHIM1
SRF-TF Ets
Homeobox
Sugar-bind HTH_38
TetR_C TetR_N
TetR_C_2 TetR_N
TetR_C_4 TetR_N
TetR_C_5 TetR_N
TetR_C_6 TetR_N
TetR_N DUF1956
TetR
TetR_C
TetR_C_2
TetR_C_3
TetR_C_4
TetR_C_5
TetR_C_6
TetR_N
WHG
TFIIE_alpha TF_Zn_Ribbon
TPR_15 PCI
Trans_reg_C BTAD
FHA
Trans_reg_C
TrmB TrmB
Trp_repressor Trp_repressor
UPF0122 UPF0122
UTRA GntR
WHG TetR_N
z-alpha z-alpha
zf-HC2 Sigma70_r2

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between the Pfam families in this clan, the corresponding UniProt entries, and the region of the three-dimensional structures that are available for that sequence.

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