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5240  structures 9026  species 0  interactions 119635  sequences 3238  architectures

Clan: Peptidase_PA (CL0124)

Summary

Peptidase clan PA Add an annotation

This clan contains a diverse set of peptidases with the trypsin fold.

This clan contains 26 families and the total number of domains in the clan is 119635. The clan was built by A Bateman.

Members

This clan contains the following 26 member families:

DUF1986 DUF316 Mycop_pep_DUF31 Peptidase_C107 Peptidase_C24 Peptidase_C3 Peptidase_C30 Peptidase_C37 Peptidase_C3G Peptidase_C4 Peptidase_C62 Peptidase_S29 Peptidase_S3 Peptidase_S30 Peptidase_S31 Peptidase_S32 Peptidase_S39 Peptidase_S46 Peptidase_S55 Peptidase_S6 Peptidase_S64 Peptidase_S7 Peptidase_S76 Pico_P2A Trypsin Trypsin_2

External database links

Domain organisation

Below is a listing of the unique domain organisations or architectures from this clan. More...

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Alignments

The table below shows the number of occurrences of each domain throughout the sequence database. More...

Pfam family Num. domains Alignment
Trypsin (PF00089) 76462 (63.9%) View
Trypsin_2 (PF13365) 38513 (32.2%) View
Peptidase_S46 (PF10459) 1744 (1.5%) View
Peptidase_S55 (PF05580) 1336 (1.1%) View
DUF316 (PF03761) 330 (0.3%) View
Mycop_pep_DUF31 (PF01732) 282 (0.2%) View
Peptidase_S64 (PF08192) 191 (0.2%) View
DUF1986 (PF09342) 147 (0.1%) View
Peptidase_S6 (PF02395) 134 (0.1%) View
Peptidase_C30 (PF05409) 115 (0.1%) View
Peptidase_C3 (PF00548) 111 (0.1%) View
Peptidase_S39 (PF02122) 106 (0.1%) View
Peptidase_S7 (PF00949) 37 (0.0%) View
Peptidase_S32 (PF05579) 33 (0.0%) View
continued
Pfam family Num. domains Alignment
Peptidase_C3G (PF12381) 27 (0.0%) View
Peptidase_C107 (PF17222) 12 (0.0%) View
Peptidase_S3 (PF00944) 9 (0.0%) View
Pico_P2A (PF00947) 8 (0.0%) View
Peptidase_C4 (PF00863) 8 (0.0%) View
Peptidase_C62 (PF12380) 7 (0.0%) View
Peptidase_S30 (PF01577) 6 (0.0%) View
Peptidase_C37 (PF05416) 5 (0.0%) View
Peptidase_C24 (PF03510) 5 (0.0%) View
Peptidase_S76 (PF13611) 3 (0.0%) View
Peptidase_S31 (PF05578) 2 (0.0%) View
Peptidase_S29 (PF02907) 2 (0.0%) View
Total: 26 Total: 119635 Clan alignment
 

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Family relationships

This diagram shows the relationships between members of this clan. More...

Species distribution

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This tree shows the occurrence of the domains in this clan across different species. More...

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Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between the Pfam families in this clan, the corresponding UniProt entries, and the region of the three-dimensional structures that are available for that sequence.

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