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1064  structures 22478  species 78  interactions 282604  sequences 2676  architectures

Clan: Peptidase_CA (CL0125)

Summary

Domain organisation

Below is a listing of the unique domain organisations or architectures from this clan. More...

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Alignments

The table below shows the number of occurrences of each domain throughout the sequence database. More...

Pfam family Num. domains Alignment
CHAP (PF05257) 66190 (23.4%) View
NLPC_P60 (PF00877) 49440 (17.5%) View
Transglut_core (PF01841) 25879 (9.2%) View
UCH (PF00443) 15951 (5.6%) View
Peptidase_C1 (PF00112) 12552 (4.4%) View
Acetyltransf_2 (PF00797) 12332 (4.4%) View
Peptidase_C39 (PF03412) 11526 (4.1%) View
Peptidase_C39_2 (PF13529) 11216 (4.0%) View
Peptidase_C47 (PF05543) 8457 (3.0%) View
Peptidase_C92 (PF05708) 8131 (2.9%) View
Peptidase_C48 (PF02902) 7414 (2.6%) View
Transglut_core2 (PF13369) 5428 (1.9%) View
Peptidase_C1_2 (PF03051) 4940 (1.7%) View
Peptidase_C2 (PF00648) 4049 (1.4%) View
OTU (PF02338) 3812 (1.3%) View
DUF1287 (PF06940) 3094 (1.1%) View
Peptidase_C93 (PF06035) 2485 (0.9%) View
Peptidase_C12 (PF01088) 2192 (0.8%) View
LRAT (PF04970) 2175 (0.8%) View
DUF1175 (PF06672) 2098 (0.7%) View
DUF1460 (PF07313) 1700 (0.6%) View
Peptidase_C6 (PF00851) 1672 (0.6%) View
Peptidase_C97 (PF05903) 1583 (0.6%) View
Viral_protease (PF08715) 1290 (0.5%) View
Amidase_6 (PF12671) 1282 (0.5%) View
Peptidase_C54 (PF03416) 1230 (0.4%) View
BtrH_N (PF14399) 1171 (0.4%) View
Rad4 (PF03835) 1032 (0.4%) View
Peptidase_C33 (PF05412) 951 (0.3%) View
Peptidase_C10 (PF01640) 945 (0.3%) View
Peptidase_C65 (PF10275) 939 (0.3%) View
continued
Pfam family Num. domains Alignment
Peptidase_C78 (PF07910) 812 (0.3%) View
UCH_1 (PF13423) 799 (0.3%) View
EDR1 (PF14381) 747 (0.3%) View
Transglut_core3 (PF13471) 729 (0.3%) View
DUF3335 (PF11814) 724 (0.3%) View
Amidase_5 (PF05382) 685 (0.2%) View
Peptidase_C28 (PF05408) 624 (0.2%) View
Phytochelatin (PF05023) 522 (0.2%) View
Peptidase_C32 (PF05411) 481 (0.2%) View
Peptidase_C9 (PF01707) 470 (0.2%) View
Peptidase_C58 (PF03543) 433 (0.2%) View
Peptidase_C31 (PF05410) 386 (0.1%) View
Guanylate_cyc_2 (PF09778) 286 (0.1%) View
Peptidase_C42 (PF05533) 276 (0.1%) View
Peptidase_C16 (PF01831) 214 (0.1%) View
Peptidase_C5 (PF00770) 194 (0.1%) View
DUF2272 (PF10030) 182 (0.1%) View
Peptidase_C23 (PF05379) 176 (0.1%) View
Peptidase_C101 (PF16218) 165 (0.1%) View
Peptidase_C7 (PF01830) 133 (0.0%) View
Peptidase_C98 (PF15499) 98 (0.0%) View
DUF553 (PF04473) 98 (0.0%) View
Peptidase_C27 (PF05407) 75 (0.0%) View
Peptidase_C21 (PF05381) 52 (0.0%) View
Peptidase_C70 (PF12385) 36 (0.0%) View
Peptidase_C34 (PF05413) 20 (0.0%) View
Peptidase_C8 (PF03569) 18 (0.0%) View
Peptidase_C36 (PF05415) 9 (0.0%) View
Peptidase_C71 (PF12386) 4 (0.0%) View
Total: 60 Total: 282604 Clan alignment
 

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Family relationships

This diagram shows the relationships between members of this clan. More...

We could not retrieve a family relationship diagram for this clan.

Species distribution

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This tree shows the occurrence of the domains in this clan across different species. More...

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Interactions

There are 78 interactions for this clan. More...

Interacting families
A B
Acetyltransf_2 Acetyltransf_2
CathepsinC_exc Peptidase_C1
CHAP GSP_synth
Cystatin Peptidase_C1
DUF1460 DUF1460
GSP_synth CHAP
Inhibitor_I29 Peptidase_C1
Inhibitor_I42 Peptidase_C1
Inhibitor_I69 Peptidase_C10
Lysozyme_like NLPC_P60
Macro Viral_protease
N_NLPC_P60 NLPC_P60
NLPC_P60 N_NLPC_P60
NLPC_P60
SH3_3
SH3_6
OTU OTU
ubiquitin
Peptidase_C1 Cystatin
DUF3586
Inhibitor_I29
Inhibitor_I42
Inhibitor_I48
Inhibitor_I71
Peptidase_C1
Propeptide_C1
Thyroglobulin_1
Peptidase_C10 Inhibitor_I69
Peptidase_C10
Peptidase_C12 Peptidase_C12
ubiquitin
Peptidase_C1_2 Peptidase_C1_2
Peptidase_C2 Calpain_III
Calpain_inhib
EF-hand_8
Peptidase_C2
Peptidase_C21 Ribosomal_S15
Peptidase_C28 Peptidase_C28
Peptidase_C33 ubiquitin
Peptidase_C47 Peptidase_C47
Staphostatin_B
Peptidase_C48 Peptidase_C48
Rad60-SLD
RanGAP1_C
ubiquitin
Peptidase_C5 MCPVI
Peptidase_C54 Atg8
Peptidase_C54
Peptidase_C65 Peptidase_C65
ubiquitin
UQ_con
Peptidase_C92 Peptidase_C92
Peptidase_C93 Peptidase_C93
Phytochelatin Phytochelatin
Rad4 BHD_1
XPC-binding
SH3_3 NLPC_P60
SH3_6 NLPC_P60
SH3_7 NLPC_P60
Staphopain_pro Peptidase_C47
Transglut_C Transglut_core
Transglut_core Transglut_C
Transglut_core
Transglut_N
Transglut_N Transglut_core
ubiquitin OTU
Peptidase_C12
Peptidase_C65
UCH
UCH EnY2
Sgf11
UBA
ubiquitin
UCH
UQ_con Peptidase_C65
Viral_protease Macro
Viral_protease
zf-UBP UCH

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between the Pfam families in this clan, the corresponding UniProt entries, and the region of the three-dimensional structures that are available for that sequence.

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