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404  structures 8832  species 5  interactions 14158  sequences 92  architectures

Clan: dUTPase (CL0153)


dUTPase like superfamily Add an annotation

This clan contains dUTPase and many viral proteins that appear to be related. dUTPases are important in virus replication.

This clan contains 7 families and the total number of domains in the clan is 14158. The clan was built by A Bateman.


This clan contains the following 7 member families:

Cytomega_UL84 DCD dUTPase Herpes_ORF11 Herpes_U55 Herpes_UL82_83 TLP-20

External database links

Domain organisation

Below is a listing of the unique domain organisations or architectures from this clan. More...

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The table below shows the number of occurrences of each domain throughout the sequence database. More...

Pfam family Num. domains Alignment
dUTPase (PF00692) 12710 (89.8%) View
DCD (PF06559) 1276 (9.0%) View
TLP-20 (PF06088) 52 (0.4%) View
Herpes_UL82_83 (PF05784) 42 (0.3%) View
Herpes_ORF11 (PF04797) 40 (0.3%) View
Cytomega_UL84 (PF06284) 27 (0.2%) View
Herpes_U55 (PF06501) 11 (0.1%) View
Total: 7 Total: 14158 Clan alignment

Please note: Clan alignments can be very large and can cause problems for some browsers. Read the note above before viewing.

Family relationships

This diagram shows the relationships between members of this clan. More...

Species distribution

Tree controls


This tree shows the occurrence of the domains in this clan across different species. More...



There are 5 interactions for this clan. More...

Interacting families
dUTPase dUTPase
MHC_I Herpes_UL82_83
RNase_H dUTPase


For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between the Pfam families in this clan, the corresponding UniProt entries, and the region of the three-dimensional structures that are available for that sequence.

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