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292  structures 22306  species 21  interactions 178209  sequences 4508  architectures

Clan: GAF (CL0161)

Summary

GAF domain-like Add an annotation

A clan of related transcriptional regulator domains.

This clan contains 11 families and the total number of domains in the clan is 178209. The clan was built by RD Finn.

Members

This clan contains the following 11 member families:

Autoind_bind CodY DUF2930 DUF3369 DUF484 GAF GAF_2 GAF_3 IclR PHY SpoVT_C

External database links

Domain organisation

Below is a listing of the unique domain organisations or architectures from this clan. More...

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Alignments

The table below shows the number of occurrences of each domain throughout the sequence database. More...

Pfam family Num. domains Alignment
IclR (PF01614) 49472 (27.8%) View
GAF_2 (PF13185) 48411 (27.2%) View
GAF (PF01590) 39521 (22.2%) View
Autoind_bind (PF03472) 8094 (4.5%) View
SpoVT_C (PF15714) 7293 (4.1%) View
CodY (PF06018) 7071 (4.0%) View
PHY (PF00360) 6324 (3.5%) View
GAF_3 (PF13492) 6138 (3.4%) View
DUF484 (PF04340) 4891 (2.7%) View
DUF3369 (PF11849) 703 (0.4%) View
DUF2930 (PF11152) 291 (0.2%) View
Total: 11 Total: 178209 Clan alignment
 

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Family relationships

This diagram shows the relationships between members of this clan. More...

Species distribution

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This tree shows the occurrence of the domains in this clan across different species. More...

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Interactions

There are 21 interactions for this clan. More...

Interacting families
A B
Autoind_bind Autoind_bind
GerE
Prok-TraM
CodY CodY
HTH_CodY
DUF484 DUF484
GAF GAF
PAS_2
PDEase_I
PHY
GAF_2 GAF_2
GAF_3 GAF_3
GerE Autoind_bind
HTH_IclR IclR
IclR HTH_IclR
IclR
PAS_2 GAF
PHY
PHY GAF
PAS_2
PHY

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between the Pfam families in this clan, the corresponding UniProt entries, and the region of the three-dimensional structures that are available for that sequence.

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