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20  structures 4354  species 0  interactions 20069  sequences 53  architectures

Clan: POTRA (CL0191)


POTRA domain superfamily Add an annotation

The polypeptide-transport-associated (POTRA) domain is predicted to be organised into three beta-strands and two alpha helices, the latter being found between strands 2 and 3. It is usually found associated with a beta-barrel outer membrane domain. It is thought to have a chaperone-like function; the proteins it is found in are involved in processes as diverse as bacterial septation and protein transport across membranes [1].

This clan contains 4 families and the total number of domains in the clan is 20069. The clan was built by M Fenech.

Literature references

  1. Sanchez-Pulido L, Devos D, Genevrois S, Vicente M, Valencia A; , Trends Biochem Sci 2003;28:523-526.: POTRA: a conserved domain in the FtsQ family and a class of beta-barrel outer membrane proteins. PUBMED:14559180 EPMC:14559180


This clan contains the following 4 member families:


Domain organisation

Below is a listing of the unique domain organisations or architectures from this clan. More...

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The table below shows the number of occurrences of each domain throughout the sequence database. More...

Pfam family Num. domains Alignment
Surf_Ag_VNR (PF07244) 14038 (69.9%) View
POTRA_1 (PF08478) 3670 (18.3%) View
POTRA_2 (PF08479) 1933 (9.6%) View
YqfD (PF06898) 428 (2.1%) View
Total: 4 Total: 20069 Clan alignment

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Family relationships

This diagram shows the relationships between members of this clan. More...

Species distribution

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This tree shows the occurrence of the domains in this clan across different species. More...



For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between the Pfam families in this clan, the corresponding UniProt entries, and the region of the three-dimensional structures that are available for that sequence.

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