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264  structures 936  species 38  interactions 3283  sequences 98  architectures

Clan: Adhesin (CL0204)

Summary

Bacterial adhesin superfamily Add an annotation

This superfamily includes a variety of bacterial adhesins that have a jelly-roll beta-barrel fold [1]. These domains are involved in sugar recognition.

This clan contains 15 families and the total number of domains in the clan is 3283. The clan was built by A Bateman.

Literature references

  1. Merckel MC, Tanskanen J, Edelman S, Westerlund-Wikstrom B, Korhonen TK, Goldman A; , J Mol Biol 2003;331:897-905.: The structural basis of receptor-binding by Escherichia coli associated with diarrhea and septicemia. PUBMED:12909017 EPMC:12909017

Members

This clan contains the following 15 member families:

Adhesin_Dr AfaD Antig_Caf1 Collagen_bind DUF1120 DUF2807 DUF4097 Fim-adh_lectin FimA Fimbrial FimH_man-bind PapG_N Saf-Nte_pilin SCPU SdrG_C_C

External database links

Domain organisation

Below is a listing of the unique domain organisations or architectures from this clan. More...

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Alignments

The table below shows the number of occurrences of each domain throughout the sequence database. More...

Pfam family Num. domains Alignment
DUF4097 (PF13349) 985 (30.0%) View
Fimbrial (PF00419) 938 (28.6%) View
DUF2807 (PF10988) 555 (16.9%) View
SCPU (PF05229) 304 (9.3%) View
Collagen_bind (PF05737) 295 (9.0%) View
FimA (PF16970) 98 (3.0%) View
DUF1120 (PF06551) 61 (1.9%) View
SdrG_C_C (PF10425) 22 (0.7%) View
FimH_man-bind (PF09160) 22 (0.7%) View
Saf-Nte_pilin (PF09460) 1 (0.0%) View
Antig_Caf1 (PF09255) 1 (0.0%) View
AfaD (PF05775) 1 (0.0%) View
Fim-adh_lectin (PF09222) 0 (0.0%) View
PapG_N (PF03627) 0 (0.0%) View
Adhesin_Dr (PF04619) 0 (0.0%) View
Total: 15 Total: 3283 Clan alignment
 

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Family relationships

This diagram shows the relationships between members of this clan. More...

Species distribution

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This tree shows the occurrence of the domains in this clan across different species. More...

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Interactions

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between the Pfam families in this clan, the corresponding UniProt entries, and the region of the three-dimensional structures that are available for that sequence.

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