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375  structures 793  species 35  interactions 5135  sequences 62  architectures

Clan: Adhesin (CL0204)

Summary

Bacterial adhesin superfamily Add an annotation

This superfamily includes a variety of bacterial adhesins that have a jelly-roll beta-barrel fold [1]. These domains are involved in sugar recognition.

This clan contains 12 families and the total number of domains in the clan is 5135. The clan was built by A Bateman.

Literature references

  1. Merckel MC, Tanskanen J, Edelman S, Westerlund-Wikstrom B, Korhonen TK, Goldman A; , J Mol Biol 2003;331:897-905.: The structural basis of receptor-binding by Escherichia coli associated with diarrhea and septicemia. PUBMED:12909017 EPMC:12909017

Members

This clan contains the following 12 member families:

Adhesin_Dr AfaD Antig_Caf1 DUF1120 Fim-adh_lectin FimA Fimbrial FimH_man-bind PapG_N Saf-Nte_pilin SCPU SdrG_C_C

External database links

Domain organisation

Below is a listing of the unique domain organisations or architectures from this clan. More...

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Alignments

The table below shows the number of occurrences of each domain throughout the sequence database. More...

Pfam family Num. domains Alignment
Fimbrial (PF00419) 2822 (55.0%) View
SCPU (PF05229) 1611 (31.4%) View
FimA (PF16970) 332 (6.5%) View
DUF1120 (PF06551) 225 (4.4%) View
SdrG_C_C (PF10425) 80 (1.6%) View
FimH_man-bind (PF09160) 53 (1.0%) View
AfaD (PF05775) 8 (0.2%) View
Saf-Nte_pilin (PF09460) 2 (0.0%) View
Fim-adh_lectin (PF09222) 1 (0.0%) View
Antig_Caf1 (PF09255) 1 (0.0%) View
PapG_N (PF03627) 0 (0.0%) View
Adhesin_Dr (PF04619) 0 (0.0%) View
Total: 12 Total: 5135 Clan alignment
 

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Family relationships

This diagram shows the relationships between members of this clan. More...

Species distribution

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This tree shows the occurrence of the domains in this clan across different species. More...

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Interactions

There are 35 interactions for this clan. More...

Interacting families
A B
Adhesin_Dr Adhesin_Dr
AfaD AfaD
SEF14_adhesin
Antig_Caf1 Antig_Caf1
PapD_C
PapD_N
Fim-adh_lectin Fim-adh_lectin
Fimbrial
Fimbrial Fimbrial
FimH_man-bind
PapC_N
PapD_C
PapD_N
Usher
FimH_man-bind Fimbrial
FimH_man-bind
PapC_N
PapD_C
Usher
PapC_N Antig_Caf1
Fimbrial
PapD_C Antig_Caf1
Fimbrial
FimH_man-bind
PapG_N
PapD_N Antig_Caf1
Fimbrial
FimH_man-bind
PapG_N
PapG_N PapG_C
Saf-Nte_pilin PapD_C
PapD_N
Saf-Nte_pilin
SdrG_C_C SdrG_C_C
SEF14_adhesin AfaD

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between the Pfam families in this clan, the corresponding UniProt entries, and the region of the three-dimensional structures that are available for that sequence.

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