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161  structures 7190  species 9  interactions 14705  sequences 62  architectures

Clan: TRB (CL0206)


Transcriptional repressor beta-barrel domain Add an annotation

This beta-barrel domain is found at the C-terminus of a variety of transcriptional repressor proteins.

This clan contains 4 families and the total number of domains in the clan is 14705. The clan was built by A Bateman.


This clan contains the following 4 member families:

BPL_C DtxR FeoA KorB_C

External database links

Domain organisation

Below is a listing of the unique domain organisations or architectures from this clan. More...

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The table below shows the number of occurrences of each domain throughout the sequence database. More...

Pfam family Num. domains Alignment
FeoA (PF04023) 9470 (64.4%) View
BPL_C (PF02237) 5142 (35.0%) View
KorB_C (PF06613) 56 (0.4%) View
DtxR (PF18357) 37 (0.3%) View
Total: 4 Total: 14705 Clan alignment

Please note: Clan alignments can be very large and can cause problems for some browsers. Read the note above before viewing.

Family relationships

This diagram shows the relationships between members of this clan. More...

Species distribution

Tree controls


This tree shows the occurrence of the domains in this clan across different species. More...



There are 9 interactions for this clan. More...

Interacting families
BPL_C Biotin_lipoyl
Fe_dep_repr_C FeoA
Fe_dep_repress FeoA
FeoA Fe_dep_repr_C
KorB_C KorB_C


For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between the Pfam families in this clan, the corresponding UniProt entries, and the region of the three-dimensional structures that are available for that sequence.

Loading structure mapping...