Sequence alignment for CL0218

PF08635

YEAH_SCHPO/190-331RYLKTVQKAKEIIKEKNLKVVSTVAKYNSAYIHNSKKFWWIMS--------ESGGPVVEQGTHFCDLSRYFGGDVEIDSI
YB64_SCHPO/169-310RYLKIVQAAKKYVADNNLNIACTIARYNSAYEHNNKLFWWYMS--------KSGGPVVEQATHFCDLSIYFGGDVDTSTV
Q55VW1_CRYNB/219-360RYLNAVREMKKIIDDNNLTVMATNARYVTAYELAIKTDWWNKS--------IMQGPIIEQGTHICDLSRYFGGDVNIETI
Q5K7F9_CRYNJ/231-373RYSAAVQKMKQILKENNLEVMMTSARYVMAYEHSAKIAWWTKS--------VDCGPIVEQATHFCDLSRYFAGEVDLDTV
Q4PF44_USTMA/241-382RYLKVVQKMKQILDENNLKVMATNARYVMAYEHTNKPDWWDKS--------ISCGPIVEQATHFCDLSRYFGGEVDLATV
Q55XR5_CRYNB/250-391RYLQCVQKMKQIIHENNLTVMATNARYSCAYEAIAKPAWWNKA--------IDMGPVIEQGTHFCDLSRYFGGDVDMNSI

PF02894

IOLG_BACSU/137-240-----KEALDNHV.IGEPLMIH.......CAHRNPTVGDN..Y........TTDMAVVDTLVHEIDVLHWLVNDDYESVQ
NTDC_BACSU/130-250-----KSLIINNE.LGNILSIKV.HFKKNSALRRKKFTWRDDAN.....SKKTSGSLGDLGIHLIDMVWYLFESDFITES
Y1686_STRPN/130-242-----KELINQGV.IGDVLYCH..TARNGWEEQQPSVSWKKIR........EKSGGHLYHHIHELDCVQFLMGGMPETVT
P72782_SYNY3/130-236-----IELLG.GV.HQAIRQNLG.KIGEVFYARYSTIMGQ...........NPAPQRWTYHHQQFGFPLVAALSRISRFT
O25390_HELPY/139-249-----KEKIKSELDKNPSKVFDITLTYISVQGKWYFSSWRADV.......NRSGGLATQMGVNIFDTLIYLFGSVKDKVI
Q00781_EMEND/158-296-----KSLLETDS.LGTVVAVNGLWTLLKPASYFAPPLGSWRAD......KKKGGVLGINLIHDIDVLQFLFGPVSRVYA
YTET_BACSU/141-276-----KEMILDGK.IGRVTSVDLNWYIDTYHGASYFKRWNRSR.......QFSGGLSVHKSTHHFDLVNWWLGQNPEEVF
YHHX_ECOLI/135-239-----KKAIESGK.LGEIVEVES.HFDYYRPVAETKPGLP...........QD.GAFYGLGVHTMDQIISLFGRPDHVAY
GAL_PSEFL/126-229-----RDWLATRT....LQSVQIDWKEDVRKWHPGQAWIWQ...........PGLGVFDPGINALSIVTHLLPLPLFVES
Y816_SYNY3/138-252-----AELLGQGI.LGQLKLIKV.DWLVGSRANPNRAWNWYAQR......EKGGGALGALASHTFDYLHWLFGPAQSLAA
PHT4_PSEPU/142-255-----RELIGSGE.FGAVKMIQA.LNYTDYLQRPRRPEELSTA........EGGGAVFSQAAHQVDVVRLLAGSRATRVR
YFII_BACSU/156-281-----RAMIEQGMIGDIRVVDLQ.YTHGFCATDEGEKISAAQKWRVDPAIAGPSFVLGDLSTHTYYMSQLIMPKMKIKEL
O23580_ARATH/150-256-----IEQVKGRD.FGNVKMV...AIREHRFPFLVKVGLNK..........MGLWTLVEKCCHFFDLMRLFAGANPVCVM
CBAC_COMTE/132-245-----KELIDSGR.YGRVRFIHS.MNYTDFLYRPRRAEELNTD........LGGGVVFNQASHQLDVIRLLAQGRVVDVS
GFO_ZYMMO/220-334-----VKLIRENQ.LGKLGMVTT.DNSDVMDQNDPAQQWRLRRE......LAGGGSLMDIGIYGLNGTRYLLGEEPIEVR
MOCA_RHIML/133-230-----RDDIRAGL.LGNLYLVS..CFQWDEAPPANSFRAT............GGGAFIDMGVHEFDQMRWLTGQEPTNFR
MVIM_ECOLI/130-227-----GELKTQLA.T.......A.ASLRMDKHRSNSVGPH...........DLYFTLLDDYLHVVDTALWLSGGKASLDG
Q39684_DAUCA/144-257-----REYLDDAEHFGQLRSIIS.CFTFAASPDYLANNIRTKPD......LDGLGALGDIGWHCIRSILWAADFELPKFA
YEG9_SCHPO/138-253-----KECIENGR.LGEVVQF...ESHIDRFRLFRKGNWKDVP.......NPGCGLVYDLGSHLIDQAITLFGTPHSVTA
O26961_METTH/134-234-----KELIENDV.IG........DVVSASAKRVGPFPPR..........IKDVGVTIDLAIHDLDVMHYLFSEPVAEVY
STRI_STRGR/133-238-----RELIAAGE.LGRVLLVR..CTAFDHRPPADAYEET............AGDIFTDCLIHDIDAVHWLTGQPTVAVQ
P72133_PSEAI/141-251-----KDKVAREK...SPHKYEVDLTYITSRGNWYLKSWKGDP.......RKSFGVATNIGVHFYDMLHFIFGKLQRNVV
YGJR_ECOLI/133-213-----RQALP..K.VGKLRKV......FFNYCQYSSRYQR.............................YLDGENPNTFN
Q55548_SYNY3/152-248-----TKILK..T.........E.ELLAIEAHRMSPYSQR..........ANDVSVVLDLMIHDIDLLLELVGSEVVKLS
YVAA_BACSU/143-250-----KKLISEGS.LEDINTYQV.SYNRYRPEVQARWREKEG.........TATGTLYDLGSHIIDQTLHLFGMPKAVTA
Y4OX_RHISN/140-254-----RALVGADA.IGRVNTVSC.RFAGDFRLYDSWGRFRH.........EMMHPMLIEGAVHHLDIMADLAGAPCTSIY
YISS_BACSU/137-245-----KRRIDAGEIGKPIYYKG...FTRDQGAPPAEFIKH............SGGIFIDCSIHDYDIARYLLGAEITSVS
Q53739_STRAD/141-252-----RKNLAR...IGDPYWFSY.DYHFNLAQPTSGWRASREQ........ALGGVLLDMGYHLIDVLSGMFPEPSRVNA
Q54368_STRLN/131-240-----ATASPAES.WAAPCGRAP.YGIAGRDGYEREWRADPRQ........VSGGQLMEQGIHVVDLLRSYFGEVEAVTS
Q45376_BORBR/142-257-----KKAIEQGR.FGRIYMVTV.NVFWTRPQEYYDAARWRGKW......EWDGGAFMNQASHYVDLLDWLVGPVESVYA
YJHC_ECOLI/130-242-----RKLIKEGV.IGEILSCH..TKRNGWENKQERLSWKKMK........EQSGGHLYHHIHELDCVQHLLGEIPETVT
YCJS_ECOLI/142-253-----REQVTNGV.LGEIYVT...TARALRRCGVPGWGVFTNKE......LQGGGPLIDIGIHMLDAAMYVLGFPAVKSV
YM94_YEAST/139-251-----KEQIEKIGPVVAFTHNSTGPFVTQNKYLTTTWRQKPE.........HIGGFLSDGGVHQLALVISLLGEFGSVSA
Y4HM_RHISN/160-282-----KHMIRNGA.VGTVRQAHV.EYVQEWATAPFSSDAKGAMWRQDPEKVGRASATGDIGTHAYHLLHTLTGQDIARLR
YDGJ_ECOLI/134-241-----KGLLAEGV.LGEVAYFES.HFDRFRPQVRDRWREQGG.........PGSGIWYDLAPHLLDQAITLFGLPVSMTV
YMO1_RHIML/136-242-----FDIVASGE.IGEVRAIQG.VFTEVNLDPKSIVNDAS..........IGGGALYDLGVYPIAAARMVFAAEPERVF
Q54531_9ACTO/141-246-----RAMLDES..VGELRLFSG.SFAVPPLAPESFRYQP..........ALGGGALLDVGVYPLRAAQLYLTGELDVLG

PF08635

YEAH_SCHPO/190-331---KVNRVEWDDPSGKLNAMPVDEKT.IPPEERIPRFTAASWKYKDGGVGAFT--HNITLQGAKYDTCIEVQADGY
YB64_SCHPO/169-310---KVNRVNWYDPCGKLAKVPVDEES.IPKEERIPRFTAASWKYKSGAVGILA--HSIILQGTNYDTCLELQADGH
Q55VW1_CRYNB/219-360---CAHALEAHEKPGRLSKLNFDESV.IPDNLRIPRATSASWKYESGAVGTML--HATALHGKDYAIELEVYADGF
Q5K7F9_CRYNJ/231-373---MAHSIEWYEKPGQLTKIPFDESALVPEDDRIPRFTSATWKYKSGAIGHLE--HGVSLQGTQFSTEITVFADGY
Q4PF44_USTMA/241-382---SAHSLEWFEPAGQLSKIPIDESK.IAEDQRIPRITCANWKYESGAVGSLT--HAVSLQGFNYSTELDVLADGY
Q55XR5_CRYNB/250-391---ASRSVEWYEEPGKLSKIPIDESK.IDEDLRVPRLTSAIWKYENGAVGSFQ--HAVALQGTAYSCELEVWADGY

PF02894

IOLG_BACSU/137-240...VIYPKKSKNALPHLKDPQ......................IVVIETKGGI....VINAEIYVNCKYGYDIQCE
NTDC_BACSU/130-250...VRAKMNTNVKTKEDKQVLVDD................YAEIYGQLKNKVF....VNIITSKCSVPEDCGFSIE
Y1686_STRPN/130-242...MTG..GNVAHEGEHFGDEDD..................MIFVNMEFSNKR....FALLEWGSAYRWGEHYVLI
P72782_SYNY3/130-236...DLFGTVQQVDAQCRFWDQ.......................PNPEYFRAC....LATAYLQFNNGLKAEVIYG
O25390_HELPY/139-249...NK...EEPDCVGGILFLE.......................HAKIRWFFS....INPEHMGVAKEKVYHKMIL
Q00781_EMEND/158-296EGTLLQRMRQNPEHTAEEGCAVTLRFASGIV.GTFLICDATPSPLNFETGTGE....NPTIPPAPSKSASDCYRIL
YTET_BACSU/141-276...AYGALNYYGPDSEWNPLPEEDGRFCGTCRVKEKCHYYSRWHPRSSKASIK....DDHLEAGDQSSLYTAYRPD
YHHX_ECOLI/135-239...DIR...SLRNKANPDDTF......................EAQLFYGDLK....AIVKTSHLVKIDYPKFIVH
GAL_PSEFL/126-229...AEL..RVPSNCQSPIAAS.......................IKMSDPRLL....DVRAEFDFDHGHDELWSIQ
Y816_SYNY3/138-252...NLS..VAIAERPDPLDNNR...................LKPVTAEDTALI....SLTLANDVPCQINITSVAH
PHT4_PSEPU/142-255...AAVGNWDPARPTEGAYTAT...................LWFENGAFASIT....YNGYGHFDSDEW.MDWVGE
YFII_BACSU/156-281...LCDRQSFVGSRAPLEDNAHV.................LMHYENGAVGTMW....TSSINAGCMDGHRIRIVGS
O23580_ARATH/150-256...ASGG.MDVNHKDEVYGGK......................VPDIIDNAYV....IIEFDNGCRGMLDLCMFAE
CBAC_COMTE/132-245...SYLGRWDAARRTEGAYSAL...................IKFDNGVAANVT....YSGYAHYNSDEV.MGWVNE
GFO_ZYMMO/220-334...AYT...YSDPNDERFVEVED..................RIIWQMRFRSGA....LSHGASSYSTTTTSRFSVQ
MOCA_RHIML/133-230..........VA.TSKTTFAG.......................AVKGDPDAV....QLLCDLSDGSSGLVSLGRR
MVIM_ECOLI/130-227...GT...LLTNDAGEMLFAE.......................HHFSAGPLQ....ITTCMHRRAGSQRETVQAV
Q39684_DAUCA/144-257...IALPGPVLNKAGVIISCG.......................ASLHWEDGK....TATLNCSFLENLTMDVTLV
YEG9_SCHPO/138-253...KLESQRQIP.PLEVEDCFR....................IVLHYLPQEGRLPLDVIVCSSSISCGLDMRYIIK
O26961_METTH/134-234...AVM..GSILEKCEYEDHA......................EIMTKFKSGI....TGILEVNWLTPYKRRKLAI
STRI_STRGR/133-238...ADG..ARLLAGSGYDVAT.....................AVLTLADGARA....VLSASRLDPHGYDHRVEVL
P72133_PSEAI/141-251...HFTSEYKTAGYLEYEQAR.......................VRWFLSVDA....NDLPESVKGKKPTYRSITV
YGJR_ECOLI/133-213...PAFSNGSIMDIGFYCLAS.......................AVALFGEPK....SVQATASLLASGVDAQG..
Q55548_SYNY3/152-248...AS...GSRASGSGYLDYV......................TATLGFSSGI....VATLTASKVTHRKIRSIAA
YVAA_BACSU/143-250...NV...MAQRENAETVDYF......................HLTLDYGKLQ....AILYGGSIVPANGPRYQIH
Y4OX_RHISN/140-254...ARTWKPEWADYKGDTDAIVL..................MDFANGAHGVYE....GSSAQATGLNDWAFEYVRV
YISS_BACSU/137-245...GHGRILNNPFMEQYGDVDQ....................ALTYIEFDSGA....AGDVEASRTSPYGHDIRAE
Q53739_STRAD/141-252...AFVHHYQEMRDRHLEDLVS....................LMCSYPSPTLS....GSLRISRHNHEKSERLCVL
Q54368_STRLN/131-240...LRS..STVWPIAPLEEDA......................MVLLRHHSGV....LAQLHSSLTQWVNTFRLEV
Q45376_BORBR/142-257...YT...ATLARRIEAEDTGVA.................ALRWRHGAMGSIN....VTMLTYPQNLEGSITILGE
YJHC_ECOLI/130-242...MIG..GNLAHSGPGFGNEDD..................MLFMTLEFPSGK....LATLEWGSAFNWPEHYVII
YCJS_ECOLI/142-253...NAHS.FQKIGTQKSCGQF.....................GEWDPATYSVE....DSLFGTIEFHNGGILWLET
YM94_YEAST/139-251...LTRQVRERSGADDIVFAT......................VQLKNKEVIG....SFTYGSAFGATEKSVFLKV
Y4HM_RHISN/160-282...AEFHTCGAVKAMEDTAYVT...................FRLENGAPGILW....VTQAAPGQYCGLRIRVWGD
YDGJ_ECOLI/134-241...DL...AQLRPGAQSTDYF......................HAILSYPQRR....VILHGTMLAAAESARYIVH
YMO1_RHIML/136-242...AVS...DLDPVFGIDRLT......................SAVLLFPGGR....QATLVVSTQLALRHNVEIF
Q54531_9ACTO/141-246....AC..LRVDETTGADVAG......................SVLLSDDRGV....TAQLDFGFEHSYRSTYALW

This alignment is coloured according to the ClustalX colouring scheme:

 
Glycine (G)
 
Proline (P)
 
Small or hydrophobic (C,A,V,L,I,M,F,W)
 
Hydroxyl or amine amino acids (S,T,N,Q)
 
Charged amino-acids (D,E,R,K)
 
Histidine or tyrosine (H,Y)

For UniProt-based alignments, we also add some additional mark-up to the alignments where appropriate. Active site information is shown as follows:

 
Active site (residue annotated in SwissProt as an active site)
 
Predicted active site (residue aligns in a Pfam alignment with a SwissProt active site)
 
Predicted active site (residue annotated in SwissProt as a potential active site)

Some UniProt sequences can be mapped to protein structures, in which case we also show the secondary structure definition. These lines are shown below the sequence to which they apply and are marked (SS). The meaning of each of the symbols is as follows:

C
Random coil
H
Alpha-helix
G
3(10) helix
I
Pi-helix
E
Hydrogen bonded beta-strand (extended strand)
B
Residue in isolated beta-bridge
T
H-bonded turn (3-turn, 4-turn, or 5-turn)
S
Bend (five-residue bend centered at residue i)
Close window