Sequence alignment for CL0218

PF08635

YEAH_SCHPO/190-331RYLKTVQKAKEIIKEKNLKVVSTVAKYNSAYIHNSKKFWWIMS--------ESGGPVVEQGTHFCDLSRYFGGDVEIDSI
YB64_SCHPO/169-310RYLKIVQAAKKYVADNNLNIACTIARYNSAYEHNNKLFWWYMS--------KSGGPVVEQATHFCDLSIYFGGDVDTSTV
Q5K7F9_CRYNJ/231-373RYSAAVQKMKQILKENNLEVMMTSARYVMAYEHSAKIAWWTKS--------VDCGPIVEQATHFCDLSRYFAGEVDLDTV
Q4PF44_USTMA/241-382RYLKVVQKMKQILDENNLKVMATNARYVMAYEHTNKPDWWDKS--------ISCGPIVEQATHFCDLSRYFGGEVDLATV
Q5KKC8_CRYNJ/218-359RYLNAVREMKKIIDDNNLTVMATNARYVTAYELAIKTDWWNKS--------IMQGPIIEQGTHICDLSRYFGGDVNIETI
Q5KM75_CRYNJ/252-393RYLQCVQKMKQIIHENNLTVMATNARYSCAYEAIAKPAWWNKA--------IDMGPVIEQGTHFCDLSRYFGGDVDMNSI

PF02894

WBPB_PSEAE/141-251-----KDKVAREK...SPHKYEVDLTYITSRGNWYLKSWKGDP.......RKSFGVATNIGVHFYDMLHFIFGKLQRNVV
IOLG_BACSU/137-240-----KEALDNHV.IGEPLMIH.......CAHRNPTVGDN..Y........TTDMAVVDTLVHEIDVLHWLVNDDYESVQ
NTDC_BACSU/130-250-----KSLIINNE.LGNILSIKV.HFKKNSALRRKKFTWRDDAN.....SKKTSGSLGDLGIHLIDMVWYLFESDFITES
P72782_SYNY3/130-236-----IELLG.GV.HQAIRQNLG.KIGEVFYARYSTIMGQ...........NPAPQRWTYHHQQFGFPLVAALSRISRFT
O25390_HELPY/139-249-----KEKIKSELDKNPSKVFDITLTYISVQGKWYFSSWRADV.......NRSGGLATQMGVNIFDTLIYLFGSVKDKVI
YTET_BACSU/141-276-----KEMILDGK.IGRVTSVDLNWYIDTYHGASYFKRWNRSR.......QFSGGLSVHKSTHHFDLVNWWLGQNPEEVF
YHHX_ECOLI/135-239-----KKAIESGK.LGEIVEVES.HFDYYRPVAETKPGLP...........QD.GAFYGLGVHTMDQIISLFGRPDHVAY
Y816_SYNY3/138-252-----AELLGQGI.LGQLKLIKV.DWLVGSRANPNRAWNWYAQ......REKGGGALGALASHTFDYLHWLFGPAQSLAA
YFII_BACSU/156-281-----RAMIEQGMIGDIRVVDLQ.YTHGFCATDEGEKISAAQKWRVDPAIAGPSFVLGDLSTHTYYMSQLIMPKMKIKEL
GFO_ZYMMO/220-334-----VKLIRENQ.LGKLGMVTT.DNSDVMDQNDPAQQWRLRR......ELAGGGSLMDIGIYGLNGTRYLLGEEPIEVR
YEG9_SCHPO/138-253-----KECIENGR.LGEVVQF...ESHIDRFRLFRKGNWKDVP.......NPGCGLVYDLGSHLIDQAITLFGTPHSVTA
IOLW_BACSU/143-250-----KKLISEGS.LEDINTYQV.SYNRYRPEVQARWREKEG.........TATGTLYDLGSHIIDQTLHLFGMPKAVTA
Y4OX_RHISN/140-254-----RALVGADA.IGRVNTVSC.RFAGDFRLYDSWGRFRH.........EMMHPMLIEGAVHHLDIMADLAGAPCTSIY
IOLX_BACSU/137-245-----KRRIDAGEIGKPIYYKG...FTRDQGAPPAEFIKH............SGGIFIDCSIHDYDIARYLLGAEITSVS
YJHC_ECOLI/130-242-----RKLIKEGV.IGEILSCH..TKRNGWENKQERLSWKKMK........EQSGGHLYHHIHELDCVQHLLGEIPETVT
YCJS_ECOLI/142-253-----REQVTNGV.LGEIYVT...TARALRRCGVPGWGVFTNK......ELQGGGPLIDIGIHMLDAAMYVLGFPAVKSV
YM94_YEAST/139-251-----KEQIEKIGPVVAFTHNSTGPFVTQNKYLTTTWRQKPE.........HIGGFLSDGGVHQLALVISLLGEFGSVSA
Y4HM_RHISN/160-282-----KHMIRNGA.VGTVRQAHV.EYVQEWATAPFSSDAKGAMWRQDPEKVGRASATGDIGTHAYHLLHTLTGQDIARLR
YDGJ_ECOLI/134-241-----KGLLAEGV.LGEVAYFES.HFDRFRPQVRDRWREQGG.........PGSGIWYDLAPHLLDQAITLFGLPVSMTV
B1W384_STRGG/133-236-----RELIAAGE.LGRVLLVR..CTAFDHRPPADAYEET............AGDIFTDCLIHDIDAVHWLTGQPTVAVQ
G5EB60_EMENI/158-295-----KSLLETDS.LGTVVAVNGLWTLLKPASYFAPPLGSWRA......DKKKGGVLGINLIHDIDVLQFLFGPVSRVYA
Q66GR2_ARATH/151-259-----.EQVKGRD.FGNVKMV...AIREHRFPFLVKVNNWNRF......NVNTGGTLVEKCCHFFDLMRLFAGANPVCVM
Q79H45_BORPE/142-256-----KKAIEQGR.FGRIYMVTV.NVFWTRPQEYYDAARWRGK......WEWDGGAFMNQASHYVDLLDWLVGPVESVYA
Q8DNU5_STRR6/130-240-----KELINQGV.IGDVLYCH..TARNGWEEQQPSVSWKKIR........EKSGGHLYHHIHELDCVQFLMGGMPETVT

PF08635

YEAH_SCHPO/190-331---KVNRVEWDDPSGKLNAMPVDEKT.IPPEERIPRFTAASWKYKDGGVGAFT--HNITLQGAKYDTCIEVQADGY
YB64_SCHPO/169-310---KVNRVNWYDPCGKLAKVPVDEES.IPKEERIPRFTAASWKYKSGAVGILA--HSIILQGTNYDTCLELQADGH
Q5K7F9_CRYNJ/231-373---MAHSIEWYEKPGQLTKIPFDESALVPEDDRIPRFTSATWKYKSGAIGHLE--HGVSLQGTQFSTEITVFADGY
Q4PF44_USTMA/241-382---SAHSLEWFEPAGQLSKIPIDESK.IAEDQRIPRITCANWKYESGAVGSLT--HAVSLQGFNYSTELDVLADGY
Q5KKC8_CRYNJ/218-359---CAHALEAHEKPGRLSKLNFDESV.IPDNLRIPRATSASWKYESGAVGTML--HATALHGKDYAIELEVYADGF
Q5KM75_CRYNJ/252-393---ASRSVEWYEEPGKLSKIPIDESK.IDEDLRVPRLTSAIWKYENGAVGSFQ--HAVALQGTAYSCELEVWADGY

PF02894

WBPB_PSEAE/141-251...HFTSEYKAAGYLEYEQAR.......................VRWFLSVDA....NDLPESVKGKKPTYRSITV
IOLG_BACSU/137-240...VIYPKKSKNALPHLKDPQ......................IVVIETKGGI....VINAEIYVNCKYGYDIQCE
NTDC_BACSU/130-250...VRAKMNTNVKTKEDKQVLVDD................YAEIYGQLKNKVF....VNIITSKCSVPEDCGFSIE
P72782_SYNY3/130-236...DLFGTVQQVDAQCRFWDQ.......................PNPEYFRAC....LATAYLQFNNGLKAEVIYG
O25390_HELPY/139-249...NK...EEPDCVGGILFLE.......................HAKIRWFFS....INPEHMGVAKEKVYHKMIL
YTET_BACSU/141-276...AYGALNYYGPDSEWNPLPEEDGRFCGTCRVKEKCHYYSRWHPRSSKASIK....DDHLEAGDQSSLYTAYRPD
YHHX_ECOLI/135-239...DIR...SLRNKANPDDTF......................EAQLFYGDLK....AIVKTSHLVKIDYPKFIVH
Y816_SYNY3/138-252...NLS..VAIAERPDPLDNNR...................LKPVTAEDTALI....SLTLANDVPCQINITSVAH
YFII_BACSU/156-281...LCDRQSFVGSRAPLEDNAHV.................LMHYENGAVGTMW....TSSINAGCMDGHRIRIVGS
GFO_ZYMMO/220-334...AYT...YSDPNDERFVEVED..................RIIWQMRFRSGA....LSHGASSYSTTTTSRFSVQ
YEG9_SCHPO/138-253...KLESQRQIP.PLEVEDCFR....................IVLHYLPQEGRLPLDVIVCSSSISCGLDMRYIIK
IOLW_BACSU/143-250...NV...MAQRENAETVDYF......................HLTLDYGKLQ....AILYGGSIVPANGPRYQIH
Y4OX_RHISN/140-254...ARTWKPEWADYKGDTDAIVL..................MDFANGAHGVYE....GSSAQATGLNDWAFEYVRV
IOLX_BACSU/137-245...GHGRILNNPFMEQYGDVDQ....................ALTYIEFDSGA....AGDVEASRTSPYGHDIRAE
YJHC_ECOLI/130-242...MIG..GNLAHSGPGFGNEDD..................MLFMTLEFPSGK....LATLEWGSAFNWPEHYVII
YCJS_ECOLI/142-253...NAHS.FQKIGTQKSCGQF.....................GEWDPATYSVE....DSLFGTIEFHNGGILWLET
YM94_YEAST/139-251...LTRQVRERSGADDIVFAT......................VQLKNKEVIG....SFTYGSAFGATEKSVFLKV
Y4HM_RHISN/160-282...AEFHTCGAVKAMEDTAYVT...................FRLENGAPGILW....VTQAAPGQYCGLRIRVWGD
YDGJ_ECOLI/134-241...DL...AQLRPGAQSTDYF......................HAILSYPQRR....VILHGTMLAAAESARYIVH
B1W384_STRGG/133-236...ADG..ARLLAGSGYDVAT.....................AVLTLADGARA....VLSASRLDPHGYDHRVE..
G5EB60_EMENI/158-295EGTLLQRMRQNPEHTAEEGCAVTLRFASGIV.GTFLICDATPSPLNFETGTGE....NPTIPPAPSKSASDCYRI.
Q66GR2_ARATH/151-259...ASGG.MDVNHKDEVYGGK......................VPDIIDNAYV....IIEFDNGCRGMLDLCMFA.
Q79H45_BORPE/142-256...YT...ATLARRIEAEDTGVA.................ALRWRHGAMGSIN....VTMLTYPQNLEGSITILG.
Q8DNU5_STRR6/130-240...MTG..GNVAHEGEHFGDEDD..................MIFVNMEFSNKR....FALLEWGSAYRWGEHYV..

This alignment is coloured according to the ClustalX colouring scheme:

 
Glycine (G)
 
Proline (P)
 
Small or hydrophobic (C,A,V,L,I,M,F,W)
 
Hydroxyl or amine amino acids (S,T,N,Q)
 
Charged amino-acids (D,E,R,K)
 
Histidine or tyrosine (H,Y)

For UniProt-based alignments, we also add some additional mark-up to the alignments where appropriate. Active site information is shown as follows:

 
Active site (residue annotated in SwissProt as an active site)
 
Predicted active site (residue aligns in a Pfam alignment with a SwissProt active site)
 
Predicted active site (residue annotated in SwissProt as a potential active site)

Some UniProt sequences can be mapped to protein structures, in which case we also show the secondary structure definition. These lines are shown below the sequence to which they apply and are marked (SS). The meaning of each of the symbols is as follows:

C
Random coil
H
Alpha-helix
G
3(10) helix
I
Pi-helix
E
Hydrogen bonded beta-strand (extended strand)
B
Residue in isolated beta-bridge
T
H-bonded turn (3-turn, 4-turn, or 5-turn)
S
Bend (five-residue bend centered at residue i)
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