Please note: this site relies heavily on the use of javascript. Without a javascript-enabled browser, this site will not function correctly. Please enable javascript and reload the page, or switch to a different browser.
98  structures 16710  species 10  interactions 53875  sequences 782  architectures

Clan: PP2C (CL0238)

Summary

PP2C-like superfamily Add an annotation

This clan includes the PP2C family of phosphatases as well as the SpoIIE family. This suggests SpoIIE proteins may also be phosphatases.

This clan contains 3 families and the total number of domains in the clan is 53875. The clan was built by A Bateman.

Members

This clan contains the following 3 member families:

PP2C PP2C_2 SpoIIE

External database links

Domain organisation

Below is a listing of the unique domain organisations or architectures from this clan. More...

Loading domain graphics...

Alignments

The table below shows the number of occurrences of each domain throughout the sequence database. More...

Pfam family Num. domains Alignment
SpoIIE (PF07228) 22944 (42.6%) View
PP2C_2 (PF13672) 18451 (34.2%) View
PP2C (PF00481) 12480 (23.2%) View
Total: 3 Total: 53875 Clan alignment
 

Please note: Clan alignments can be very large and can cause problems for some browsers. Read the note above before viewing.

Family relationships

This diagram shows the relationships between members of this clan. More...

Species distribution

Tree controls

Hide

This tree shows the occurrence of the domains in this clan across different species. More...

Loading...

Interactions

There are 10 interactions for this clan. More...

Interacting families
A B
Pkinase PP2C
Polyketide_cyc PP2C
Polyketide_cyc2 PP2C
PP2C BIR
Polyketide_cyc2
PP2C
PP2C_C
PP2C_2 PP2C_2
SpoIIE HATPase_c
SpoIIE

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between the Pfam families in this clan, the corresponding UniProt entries, and the region of the three-dimensional structures that are available for that sequence.

Loading structure mapping...