Sequence alignment for CL0250

PF08887

Q988W1_RHILO/12-112QPLEAFNARFG.....SPAPV.GLASSEILEPLPPGFPDALG---EYWGQRGFGAYGDQLIWTQPPG------SFDDVIE
I6XYA4_PROPF/15-117EQLQKFFEDEG.....GPLGVGETASPEVLEYFEGILPASTL---QIWRTIGFDGLAGGRHWITNPL------EWAPAVD
Q7CSZ3_AGRT5/13-116KWIEELLNAYEIDHIVKPSA.......QIVERYKDRLPEILV---KFWIEKGWCSWSKGQYWICDPS------IFQPVID
Q88F69_PSEPK/3-109VIFSIFLETFG.....DPIGQ.QPVPPAAVDHYQGKLPNRLL---EYWQDHGWCGYGGGLFWLVNPQ------EYQGVVA
Q887W6_PSESM/2-101.......ETFG.....GQVGR.QEVPESSIDRYRGKLPNQLL---TYWAEHGWCGYGDGIFWTVNPQ------EYDAVVA
Q7CUQ2_AGRT5/7-111.TYENALKRFG.....LPENP.EIMGEADIARYKNRIPETYL---DFIRHAGLGIWKQGYFQFCNPE------KYKSIVA
Q88PR6_PSEPK/3-109KVLASLIENFG.....PPIDR.REVPGSTIERYRDKLPPKLL---EYWSEHGWGGYGEGILWLVNPQ------EYDAVVS
D5UQQ3_TSUPD/6-110..FELFLRDVP.....LTTAG.PACTQQHLDTYRGVLPNPLL---SYWQEYGFSGFGDGIVWLTDPL------EWQATTT
Q88PR4_PSEPK/3-109EVFSLFVEQVG.....EPFFR.QEVPPSSLDRYRGILPNKLL---AYWSEHGWCGYGDGIFWTVNPQ------EYEGVTA
Q88F70_PSEPK/3-109EVFSIFLDNIG.....APFSR.REVPPSSIDRYNGKPPELLL---AYWKEHGWCGFGEGIFWLVNPQ------EYEGVVS
Q883B0_PSESM/4-108ESFEIFVDAMG.....EPVKV.CPASESVIDKYKGVLPDVLL---DYWRSEGWCGYADGLFWTVNPD------EYKHLLD

PF02938

SYDND_SYNY3/315-415--FSAAVSS..-----GGSIK-AIRVPGGNETISNVRIKPGGDLFKEATEAG----AKGIAYIRVRD.....NGEIDTIG
SYDND_RICPR/315-409--FRENIKK..-----GSVVH-AIPAPQ.AASLPRSFFDKMI...EFAISKG----ARGLGYIQFSE....SGEAKGPLS
SYDND_HELPY/307-403--FSNTAKDPK-----NKRIK-ALNVKGADALFSRSVLKELE...EFVRQFG----AKGLAYLQIKE.....DEIKGPLV
SYDND_PSEAE/310-409--FSGPAND.P-----KGRVA-ALRVPG.AASMPRSQIDDYT...KFVGIYG----AKGLAYIKVNERAKGVEGLQSPIV
SYD_ECOLI/307-406--FAGPAND.P-----KGRVA-ALRVPGG.ASLTRKQIDEYG...NFVKIYG----AKGLAYIKVNERAKGLEGINSPVA
SYD_HAEIN/308-407--FNEPANN.P-----NGRVA-VIRVPNG.AEITRKQIDEYT...QFVGIYG----AKGLAWAKVNDINAGLEGVQSPIA
SYDND_AQUAE/319-411--FKSVVEA..-----GGIIK-AINFKG..SNLSRKEIDELT...KFVQSLG----AKGLAWIKVEK.....DKLTSPIV
SYDND_BACSU/314-408--FSSAVAN..-----GGVVK-AINVKGGAGDYSRKDIDALG...AFAANYG----AKGLAWVKVEA.....DGVKGPIA
SYDND_CHLTR/313-406--FLDQLAY..-----GGTVK-GFCVPGG.ADMSRKQLDIYT...DFVKRYG----AMGLVWIKKQD.....GGVSSNVA
SYDND_THEMA/308-401--IRNVLNE..-----GGSVK-GFIVPGFASEMSRKKGEELM...ARMKELG----LGGLIWFKLDG......GITSPHL
SYD_DEIRA/309-394--FASA.....-----.PSVK-VLVAPE....LTRKQIDELE...RVAKQNG----AGGLAWLRRDG.....EGFTGGIS
SYDND_TREPA/328-422--FEEVVAQ..-----GGSIR-ALVLPGKARCYSRRQIEALE...SIARAHE----AHHLFWLKATG.....GGLEGGIA
SYDND_BORBU/309-403--FKDTLKN..-----KGSIK-ILIVKDKADKFSRAKINNLE...EIAKLYK----TQGLYFTKIEN.....NKFSGGIA
GATE_ARCFU/294-382--IRN......-----.KTVK-AILLRG.FGGIVGREIQPGR...RLGTEFA----DIAKTY.GLGG.....VFHTDELP
GATE_METTH/292-381--ISSA.....-----.ESVL-AVKLRG.FDGLIGVEIQPGR...RLGTEMA----DYAKKR.GVSG.....IFHTDELP
GATE_METJA/295-390--IQNALKK.K-----NGKVK-AVLLKG.FAGLVGKEIQPGR...RLGTEFS----DRAKVIAGVGG.....LFHTDELP
GATE_AERPE/299-394--IKKVLSS..-----GGKVI-AVKLPR.MKGIIGMEIMPGR...RFGTELA----DYARFWGGVGG.....IIHSDELP
D7MGF9_ARALL/390-489--FTEALES..-----GGIIK-VLCVPLGAKKYSNSALKKGDI.YNEAMKSG----AKGLPFLKVLD.....NGEIEGIA
SYD_THET8/315-400--.QEA.....-----.ESVK-ALALPKA...LSRKEVAELE...EVAKRHK----AQGLAWARVEE.....GGFSGGVA

PF08887

Q988W1_RHILO/12-112EWIGTGA.......KDSVLLVRFSFG-DFVVWA..RGRTFFVNVHR
I6XYA4_PROPF/15-117SWLEGME..LPFPPQRWWCVTRTPMG-SMQLWGEVSGPAL......
Q7CSZ3_AGRT5/13-116YVFLGDS...ELDPTRMVAFGYNAFG-NVDIWYGD..ATIRLNLPN
Q88F69_PSEPK/3-109SWLAGTH...FEACDTYHLIARSAFG-DLYLWGEKTGSVLTIAAYH
Q887W6_PSESM/2-101SWLEGTK...FETFDAYHLIARSAFG-DLYLWGEEIGASLKITSIL
Q7CUQ2_AGRT5/7-111LALGGDK...QLNPVRTHALGFSAFG-KILAWNEDY.KTTEINILL
Q88PR6_PSEPK/3-109CWIAGTA...LASHDSYHLVARSAFG-DLYLWGEKTRFSLEITSVG
D5UQQ3_TSUPD/6-110LITAGITHRPLGTDATYIPILRTAFG-KIWFWTPGFGRSLTIT...
Q88PR4_PSEPK/3-109SLIEGTI...LEKRDRYHLIARGAFG-DLYLFGEQTGFSVKILAHI
Q88F70_PSEPK/3-109SWTEGTL...LENRDTYHLIARSAFG-DLYLWGENSGFSVKITSLL
Q883B0_PSESM/4-108MWLSGTK...FSGIDNYHVIARSAFG-DLYAWGEKYGRKIIVSC..

PF02938

SYDND_SYNY3/315-415AIKENLD---EAQVKTLLQLTQAEAG.DLLLFGAGD.TATVDKSL-
SYDND_RICPR/315-409KF...LT---GQQLEILKATANTSNG.DAVFFVSDK.KDEAVKLC-
SYDND_HELPY/307-403KF...LS---EKGLKNILERTDAQVG.DIVFFGAGD.KKIVLDYM-
SYDND_PSEAE/310-409KF...IP---EANLNVILDRVGAVDG.DIVFFGADK.AKIVCDAL-
SYD_ECOLI/307-406KF...LN---AEIIEDILDRTAAQDG.DMIFFGADN.KKIVADAM-
SYD_HAEIN/308-407KF...LN---EDVWKGLAERVNAQTG.DILFFGADK.WQTTTDAM-
SYDND_AQUAE/319-411KF...FT---EEETQKLLERTKAEPG.DVILFSADK.KEMVYKIL-
SYDND_BACSU/314-408KF...FD---EEKQSKLIEALDAAEG.DLLLFGADQ.FEVVAASL-
SYDND_CHLTR/313-406KF...AS---EDVFQEMFEAFEAKDQ.DILLLIAAP.EAVANQAL-
SYDND_THEMA/308-401KH....L---EKEFRKIAETENMNEG.DVCLIAAHTDRNLLNEAL-
SYD_DEIRA/309-394KF....V---GGIAPQLIEQTGVAQG.GTLLFAAGE.WKKAVTAL-
SYDND_TREPA/328-422RF....F---AGVESEVRRRLSAQDE.DLLLFVADCRHRVCCVAL-
SYDND_BORBU/309-403KF....L---KTEEQELIKTYSLENN.DIIFFTANNNWETACKAM-
GATE_ARCFU/294-382AY..GIS---EEEVSRLRDAVGAEDG.DAVVMAAGD.AVRVERAL-
GATE_METTH/292-381AY..GIT---EEEVRGLRDAVGASQG.DAVVMVAHE.RVTAENAL-
GATE_METJA/295-390KY..GIT---EEEVKKLKEFVNAEEN.DAVIIVADE.ESKVDRAL-
GATE_AERPE/299-394GY..GIT---GDEVEKIYEAVGGDPGVDAFALVADK.PSNALRAA-
D7MGF9_ARALL/390-489ALVSSLD---SAGKINFVKQCGAAPG.DLILFGVGP.VTSVNKTL-
SYD_THET8/315-400KF....L---EPVREALLQATEARPG.DTLLFVAGP.RKVAATAL-

This alignment is coloured according to the ClustalX colouring scheme:

 
Glycine (G)
 
Proline (P)
 
Small or hydrophobic (C,A,V,L,I,M,F,W)
 
Hydroxyl or amine amino acids (S,T,N,Q)
 
Charged amino-acids (D,E,R,K)
 
Histidine or tyrosine (H,Y)

For UniProt-based alignments, we also add some additional mark-up to the alignments where appropriate. Active site information is shown as follows:

 
Active site (residue annotated in SwissProt as an active site)
 
Predicted active site (residue aligns in a Pfam alignment with a SwissProt active site)
 
Predicted active site (residue annotated in SwissProt as a potential active site)

Some UniProt sequences can be mapped to protein structures, in which case we also show the secondary structure definition. These lines are shown below the sequence to which they apply and are marked (SS). The meaning of each of the symbols is as follows:

C
Random coil
H
Alpha-helix
G
3(10) helix
I
Pi-helix
E
Hydrogen bonded beta-strand (extended strand)
B
Residue in isolated beta-bridge
T
H-bonded turn (3-turn, 4-turn, or 5-turn)
S
Bend (five-residue bend centered at residue i)
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