Sequence alignment for CL0262

PF13623

C6I507_9BACE/4-147-LQNIRS--.--.----KGPLLVIVIGLALFAFIA.GDA.WKV-LQPH.QSH-D.VGEVNGETLSAQDYQN---------
D3HY39_9BACT/4-150-LGKIRS--.--.----RGLILICIIGFGLFAFIAEELF.RSC-ESSRNDQR-QQVGEVLGEKISVQDFQK---------
D3II58_9BACT/4-150-LGKIRS--.--.----RGMILIGIIGLGLLAFIAEEAF.RSC-EATRNNQR-QQVGEVNGEKISVQEFQK---------
D9RVL8_PREMB/4-150-LGKIRS--.--.----KGGILVGAIGLALFAFLA.GDAARSC-DGIKGEAR-QQIGEILGKKISVQDYQK---------
D1XVV4_9BACT/4-150-LGKIRS--.--.----KGALLMIVIGLGLLGFLVEEGA.RSC-SGLKAEQH-SQVGEILGEKISNQDFQK---------
C6YVX2_9GAMM/2-125-LQSFND--R--L----KGPFTWIIIISISFIFVI.SGM.TFF-FTNIGSSR-SYVAKVGDNEIGLQQFQQ---------

PF13624

B7TX43_PSEFL/1-165MLQNIRD..N..S....QGWIAKTIIGIIVALMAFT..GIEAI.FQASGNNK.QDVAKVNGEEITQTELSQ.....AVD.
D3SMV5_THEAH/1-156MFSFIQR..H..R....K..FLVVTVSVVSFAFFLWLFLAGSV.QDILRGKR.ACVAVVNGTCISLRDYRM.....ELL.
B4U8V8_HYDS0/1-151MFEFIRK..H..K....E..TFAILSGIVTAAFFLWNFAAGNI.TSLFHSSE.NCIAKANGDCISIADFRR.....VAM.
B5EQ33_ACIF5/1-165MMETFRNFGR..S....W..VAKSLMVLIALSFVLW..GVSGYLFSGH.STS.SVVATVDGQKISDAAFQK.....RMKD
E6TYN9_BACCJ/1-153MFKYFKF..N..N....S..IFIISIAVLLIL.ILAPFNKGKM.EEQV.EID.AVVATVNGENIIYKDVIKVKNSMRLK.
C7MZH2_SACVD/1-146MIRTIRR..YPSR....R..SFGVVLTAVTALL.LA.....SC.GSDP.AQA.RSAAVVGDHVIQLDEVQA.....EVR.
A3EPT2_9BACT/1-171MLEWIRK..V..AVERPK..VLGTLMILVGAIFVVS.MGWWGF.SAYK.SGKPGIVARINGTPLYATEFSR.....DYE.
C6HWQ2_9BACT/1-170MLEWIRR..E..AVERPK..VIGVLILLTGGIFVLS.MGWWGF.SQSGSSGG.DVVAKVDGVPIKAKDYSR.....DYLI
B5YGW7_THEYD/1-157MIKTLRK..N..A....K..YFYFLFFLVIITFVFW..GVGTV.DK...PKV.EYVADVDGQKISAERFWR.....NYE.

PF09312

SURA_AROAE/35-152--------------------------------------------VD-------HIAAVVNNEVITARELRE---------
SURA_VIBVY/24-141--------------------------------------------LD-------KVAVIVNDGVILQSDIDT---------
SURA_RALSO/87-204--------------------------------------------VD-------EVVAVVNTDIITRRELLD---------
SURA_CHRSD/29-146--------------------------------------------LD-------RIVAVVNKDAIMQSRLED---------
Q1V6U0_VIBAL/24-141--------------------------------------------ID-------KVAVIVNDGVVLQSDIET---------
Q2BK15_9GAMM/30-147--------------------------------------------LD-------RIAAVVNEGIILQSELEQ---------
Q2BZR3_9GAMM/27-144--------------------------------------------LD-------QVVMTVNDGVILQSDVNA---------
SURA_HAHCH/34-151--------------------------------------------LD-------RVVAVVNDDIVLYSELQD---------
SURA_NITMU/36-153--------------------------------------------ID-------HIVAVVNENVITRHELDE---------
SURA_NITOC/23-140--------------------------------------------LD-------RIVAVVNEDIVLESELEQ---------
SURA_PSEPF/18-135--------------------------------------------ID-------RVVAIVDNDVVMQSQLDQ---------
Q3RGI7_XYLFA/33-150--------------------------------------------LD-------RIVAVVDDNVVLKSELDR---------
SURA_THIDA/35-152--------------------------------------------LN-------HIVAVVNDEVITRQELAK---------
C1DIW7_AZOVD/32-149--------------------------------------------LD-------RIVAIIDNDVVMQTQLDR---------
SURA_VIBF1/27-144--------------------------------------------LD-------RVVAIVDEGVVLQSDIDT---------
SURA_SALPA/25-142--------------------------------------------VD-------KVAAVVNNGVVLESDVDG---------
SURA_METCA/30-147--------------------------------------------VD-------RIVAVVDDGVILESELVR---------
SURA_YERPS/25-142--------------------------------------------VD-------KVAAVVDNGVVLQSDIDG---------
SURA_XANCP/31-148--------------------------------------------LD-------RIAAIVDEDVVLQSELDR---------

PF05698

TIG_BORBU/272-432TLDDLKN-------------FIRSSLL.NIVEEKKETLKLNKF-FSTISEKL-EI...DIPHSMIEAEIEI---------
TIG_MYCTU/258-419SIDELRA-------------SLSDQVR.QAKRAQQAEQIRNAT-IDALLEQV-DV...PLPESYVQAQFDS---------
TIG_RHOCB/265-420DLEALKG-------------QVASRLE.AEYKGASRAILKRAL-LDILDAQV-KF...DLPPSLVEAEAGQ---------
TIG_TREPA/266-420TLDDLTR-------------SVRQNLA.EALEAALHEYKRRQL-LRILVREN-PF...SLPESLVVGEMES---------
TIG_CHLTR/273-432SLEDLKK-------------KLRIQLE.NQAKEAQHQKRFSDA-EDALAQLI-DF...DLPESLLQEREEL---------
TIG_CAUCR/268-426DLAALTE-------------LLKSNLA.GRYDNSSRFKLKRAL-LDVLDTKH-DF...PLPPRMVDAEFAG---------
TIG_HAEIN/262-413SVADLRA-------------EIRKNME.RELKNALVSRVKQQV-INGLIEQN-PI...DVPVSAVEEEINV---------
TIG_MYCGE/275-440SLKAFKS-------------YFHKLME.NKKQETILQENNQKI-RQFLLTNT-KL..PFLPEALIKLEANR---------
TIG_HELPY/268-427TLKLLKE-------------RVEGQLFLENKARLYNEELKEKL-IENLDEKI-VF...DLPKTIIEQEMDL---------
TIG_BUCAI/263-415TIQTDYQ-------------TIKNNLH.SQINIITDKYLENQI-IQKIVEKN-IL...LLPPLLFQKEIKN---------
TIG_PASMU/262-413TVDDLRN-------------EIRKNMQ.RELKNALTAKVKGQV-IDGLLAQN-AI...DVPASAVEQEIEV---------
TIG_SALTI/262-413SVAGLRA-------------EVRKNME.RELKGAVRNRVKSQA-IEGLVKAN-DI...DVPSALIDSEIDV---------
TIG_STAAW/264-422TVDEYKE-------------NLRKRLA.EQKATDAENVEKEEA-ITKATDNT-TI...DIPEAMVNTELDR---------
TIG_MYCPN/275-440SLKEFKT-------------YFHKLVS.AKKLEITLQENSVKI-RQFFLANT-TL..PYIPDSLIKLESDR---------
TIG_BACSU/264-422TLAELTE-------------KTKKRLE.EAKENEADAKLREEL-VLKASENA-EI...DVPQAMVDTELDR---------
TIG_CAMJE/268-427SVEVLDE-------------KLKEQIKNEKLFKLVNDELKGKF-ADALIEKY-NF...DLPKGIVEQETDM---------
TIG_SYNY3/277-441TMAELKA-------------DLEKQFQ.EQAKQRTDDNIKAAI-KKKLGELF-TG...DLPETMIKQECDR---------
TIG_STRP6/264-422TLEDLKV-------------KYRKELE.AAQETAYDDAVEGAA-IELAVANA-EI..VDLPEEMIHEEVNR---------
TIG_BUCAP/270-415T......-------------.IKNNII.EKIKSLTQNHLQNQI-IKQLIIKN-PI...NIPPTLLREETNF---------
TIG_CHLTE/257-411KVEDFRN-------------DIRLQLQ.AHFSDKSEYDLLEAI-SSKLIEEH-PV...PTPSAMVAHFQNI---------
TIG_CORGL/258-419TIEELRE-------------STVSDVE.AKQKNEQAAAIRDEV-LAAALGEA-DF...ALPQSIVDEQAHS---------
TIG_XANAC/258-413DAEQFRA-------------DIRTNLE.RELKGALMNRLRREV-GEQLIAAY-AH..VEMPPRLVESEARS---------
TIG_FUSNN/261-426SLDELKA-------------KTKEETT.KRENDRIENEYVSAL-LDKLMETT-TI...DVPVSMVQAEIQN---------
TIG_THETN/263-423TLEELKQ-------------DIRKKLE.EKNKREAENEMKEKA-VMKVVENA-KV...DIPDVMVERQIDL---------
Q8RPF7_DESHA/157-313SLEQLKS-------------RLKEVIS.ENWLQSIAEARMKAI-LNAIFSTS-VC...ELDQQELKEVSDR---------
Q8RPH5_DESHA/154-311TLQEFKE-------------VLAAEIT.QEKKTRAQGANIDRV-FQAIAGRC-KY...EFDPEVLNQAAEN---------
Q8RPJ3_DESHA/155-300GMEELKN-------------NLRSIIT.ANWSQVIAENKLELI-FETILAQS-EY...EFDEEEFQKAYAD---------
TIG_ARATH/379-538TLKEVEE-------------TLAKRCQ.EMEQEAKEQATDNAI-LEQIRKMV-EV...EIPQSLFEEQGRQ---------
TIG_AGRT5/268-426SAEKLKE-------------IVKGQIE.SQFGNVTRQKVKRQI-LDQLDEMY-KF...DTPAGLVDAEFDN---------
TIG_CLOPE/263-425TLEELKA-------------DLKEKAV.KANELRAKREMEEKV-INAVVDNA-KV...EIPEAMINREVEN---------
TIG_RALSO/273-427SLDKMRA-------------DIRENLE.REVKRRTHALLKDQV-MDALLKVA-EL...DVPKSLIEQDQER---------
TIG_LISMO/264-422TLDELKE-------------KISKRLQ.EAKEESVAQAKQEEV-IAKAVENA-EV...DIPHAMVHHEADH---------
TIG_BRUME/268-426SLERLRQ-------------VVREQIE.SQYGQITRQKVKRQI-LDALDGDY-QF...ETPQKLVDAEFNN---------
TIG_NOSS1/279-432TLEALRA-------------SLAERYQ.KEAEDKTKNNQQEAL-LGELVKHI-EV...DLPETLIEKEVDA---------
TIG_RICCN/261-416SLEELRT-------------HFTKQIE.NESEEAINTIMKMNL-FDKLEKLL-DF...DVPESLLEQEKNI---------
TIG_SYNE7/273-427TIEELKT-------------ALTERFQ.AEHESEVKASKRDAI-LTALADQL-DV...EIPESLLQREISA---------
TIG_CLOAB/264-425TLDEVKA-------------DIRSKME.KANEEKAKIEFEDKV-VDAAVENA-KI...EIPEVMVKNETDQ---------
TIG_STRPN/264-422TLADLKE-------------KYSKELA.AAKEEAYKDAVEGAA-IDTAVENA-EI..VELPEEMIHEEVHR---------
TIG_RHILO/268-427SLERLRE-------------IVRGQIE.NQFGSMTRQKVKRQL-LDQLDAAY-SF...EAPSKLIDAEFNN---------
TIG_MYCPU/270-429NLEQLKE-------------YLRPSIE.HKLLEDSLTEFKNEA-FNKIKELN-DI...KIPRGLLLEEMTA---------
TIG_MYCLE/258-419TMAELRA-------------NLGDQVR.KAKYAQQAEKIRDAA-VDALLERV-DV...PLPEGIVQAQFNN---------
TIG_LACLA/264-422TLDELKA-------------KFRKELE.ESKAEAYNDAVETAA-IEAAVANA-EI..KEIPEEMIHEEVHR---------
TIG_STRCO/258-420TLEELQA-------------DSRKRLA.NMKQYDQATQAQERV-LDKLLELV-EV...PVPEKLLEDEINT---------
TIG_PSEAE/262-412GLDGFRA-------------EVQKNME.RELRQAIKSKVKNQV-MEGLLQAN-PI...EVPKALIGNEVNR---------
TIG_NEIMA/264-418DVAKMRE-------------EVKKNVS.REVERRVNEQTKESV-MNALLKAV-EL...KAPVALVNEEAAR---------
TIG_BACHD/264-425SLDELKK-------------KLREKLE.KDRAHEADHEKRDTL-IQKASENA-TI...DIPEAMINTELDR---------
TIG_VIBCH/262-413GVDALKA-------------EVRKNME.RELKQAIKARIKEQA-IEGLVKEN-EI...QVPSALIDQEINV---------
Q9LAS3_9FIRM/151-307SMEELKN-------------NLRGIIA.DNWSQVIAESKLEMI-FEEILAYS-EY...EFDEEEFKKVYED---------
TIG_XYLFA/259-414KLEDFRA-------------DIRANLE.RELKGALVSHLRREV-GEQLIAAY-AH..VEMPPRLVEKEARL---------
TIG_UREPA/274-434TVQELKD-------------YIHNQIV.LAKQEKNSERAWLEI-AQQLLAKA-KI..TPIPQSLIDREVST---------
TIG_OENOE/271-430VLEELKA-------------KTKEKLA.KDKAEKNKDAFEDAA-IQKVVDGA-KINPEKLPEEMINDDVSR---------
TIG_DEIRA/249-416SMDKLRT-------------DLREELE.RRAQQEGDNLRREEL-VGHLVEGM-TV...EIPQALIDRRREG---------
TIG_THEMA/247-403TLEQLKE-------------SLKKEGK.EIYDVEMKESMREQL-LEKLPEIV-EI...EISDRTLEILVNE---------
TIG_AZOBR/262-419SLEKLRE-------------AVGRPHQ.GRIRQRVALRVKRQL-LDKLAEAH-SF...EVPPGMVDVEFEG---------
TIG_CHLPN/272-431SLDDLKA-------------KLRIQLE.KQAKDKQLQKRFSEA-EDALAMLV-DF...ELPTSLLEERISL---------

PF13623

C6I507_9BACE/4-147----------M----VEEYTEVI---K.FSSGM.SSLNDEQTN..---.QVKDE-----VWRSYVNNKLIEKEAKKLGIT
D3HY39_9BACT/4-150----------L----LDEYQEVI---KMQQGTE.TL...SEEQL.---NQVKDM-----VWNTYVQSKLVEKEAKELGLT
D3II58_9BACT/4-150----------M----VDEYAEAI---K.MQQGQ.DN...LNDEQL---NQVKDM-----VWTSYVQNKLVEKEAKELGLT
D9RVL8_PREMB/4-150----------L----IDEYQSAI---K.FTMQRDNL...TDQEL.---KQVEDQ-----VWQQLVSNRVIEADAEKVGLT
D1XVV4_9BACT/4-150----------L----IEEYQSAI---K.LTMQR.DN...LSEEEL---NQVKDQ-----VWQQLVSNRVLEADAKKVGLT
C6YVX2_9GAMM/2-125----------Y----AQNAT...---...............TE..---.SQKRA-----VLDQMINQYLILADAQRHNIV

PF13624

B7TX43_PSEFL/1-165...M......Q----RRQLM...---...QQLGKDFDASLLDEKL.....LRDA.....ALKGLIDRKLLLQGAADSKFG
D3SMV5_THEAH/1-156...P......Y----SQFLK...---...NEE.........MEGM.....IKEQ.....VLDSLIVRELLYQKALEMGFV
B4U8V8_HYDS0/1-151...G.......----....T...---...NQQ.........MTPI.....LKQE.....ILNSLIDDDLLYEQAKKEGFL
B5EQ33_ACIF5/1-165ALAR......Y----SHIFG...---...ATT.........AAKMAADRSFGLE.....VLNGLIDNMLLGMEAGRLGLQ
E6TYN9_BACCJ/1-153...K......Y----NDLTN...---...N...........NEDK.....LTEA.....AIEQRIIHRLLIQEAQRLNIE
C7MZH2_SACVD/1-146...WLLDHAPQ----AQQAR...---...EQR.........RIDQ.....ISSE.....IVRSRVVHELLAVAEERENLR
A3EPT2_9BACT/1-171...I......M----KNNYQRL.---LLNGAL.........GKKILTELNFPGL.....VLRNMIFRQLWIDEANHLHLI
C6HWQ2_9BACT/1-170MKDN......Y----KRLLR...---...GDL.........GAKI.....LKDLNFPGLVLRNMIYRQLWIDEGKSLGIA
B5YGW7_THEYD/1-157...E......I----RRFYREVF---KDKAAE.........MEQG.....LKEK.....VLEDLINEEILLWLAKKYEIE

PF09312

SURA_AROAE/35-152----------R----VEQAI------HQLNRQ---------GTPQPPADVLERQ-----LLERLVLERAQLQLARETSLQ
SURA_VIBVY/24-141----------A----TKTLR------ANAKKS---------GQALPDADVLNEQ-----IVDKLIIDTLQTQEADRIGVR
SURA_RALSO/87-204----------R----ADLVE------RTLQSQ---------NRQVPVRADLLGE-----VLEQLILERVQAQTAKESGIR
SURA_CHRSD/29-146----------R----VTQVR------RQMASR---------NVPAPNEADLRRQ-----VLDRMILEQIQLQMAERANLS
Q1V6U0_VIBAL/24-141----------A----MKTLQ------ANARQS---------GKSLPSTSVLKEQ-----VVEKLIIDTLQGQEADRIGVR
Q2BK15_9GAMM/30-147----------R----TSITR------EQLQSR---------NTRIPPEHILRKQ-----VLNRLIIESIQKQMAEQNGVR
Q2BZR3_9GAMM/27-144----------M----LKTVH------LNAAEE---------HQQLPPNNILRQQ-----VMDKLILENLQLQQAQQLGIR
SURA_HAHCH/34-151----------R----ASRIK------DKLRQQ---------KTPLPPEAVLHEK-----VLDQLVLESIQMQMADRGGIR
SURA_NITMU/36-153----------M----LGAML------KQLQKQ---------GVQPPPPAVLEKQ-----LLERIILNRVQLQLANETGLT
SURA_NITOC/23-140----------M----VRTVQ------DQLAAQ---------GTSLPPGYVLERQ-----VLERLVMEQLQLQLAARTGIQ
SURA_PSEPF/18-135----------R----VHEVQ------QTIAKR---------GGGLPPPGVLDQQ-----VLERLIVENLQLQIGERSGIR
Q3RGI7_XYLFA/33-150----------A----IHNVK------SQYVGH---------EGQLPPDEVLQRQ-----VLERLILIKLQVARAQTNGIR
SURA_THIDA/35-152----------R----YDEVV------RNLSRQ---------NTPLPPRNVLEKQ-----LLERMVTELALQQHARNTGVR
C1DIW7_AZOVD/32-149----------R----LREVE------QTIAKR---------GAQLPPRDQLVSQ-----VLERLILESIQLQMGSRAGIR
SURA_VIBF1/27-144----------S----LKTVK------INAQEK---------GQPLPDEAVLREQ-----VLEKLIVDTIQSQQAEKMGIR
SURA_SALPA/25-142----------L----MQSVK------LNAGQA---------GQQLPDDATLRHQ-----ILERLIMDQIILQMGQKMGVK
SURA_METCA/30-147----------K----VDEIK------RSLRAS---------RASLPPDSVLVRQ-----VLERMIVDKIQIQMAEKMGIQ
SURA_YERPS/25-142----------L----LQSVK------MNAQQS---------GQQVPDDSTLRHQ-----ILERLIMDNIQLQMAKKMGIT
SURA_XANCP/31-148----------A----VRNVK------SQYAGR---------DNQLPPDDVLQRQ-----VLERLVLVKLQVGRAEGSGIR

PF05698

TIG_BORBU/272-432----------A....FKDAKRQN..KNNMSLEEFKSIFYS..SGYIGGDNLKDE-----ILGNLKSKLIMQKMVDLDPIK
TIG_MYCTU/258-419----------V....LHSALSGL.NHDEARFNELLVEQGS..SRAAFDAEARTA-----SEKDVKRQLLLDALADELQVQ
TIG_RHOCB/265-420----------I....AHQL..........WHEENPDHHGHDHGAVEPTEEHKTL-----AERRVRLGLLLAELGRNEKIE
TIG_TREPA/266-420----------RWALVMRQF..............GVSLSGTPQNKLQFFQQWRPE-----VEEHLKQRVIVELLLKQEQVS
TIG_CHLTR/273-432----------L....SREKLLNA......RLVKYCSDSELEEQKQALLEEAKAD-----ARKAVKLLFLTQKVFSEKGLS
TIG_CAUCR/268-426----------I....WQQVEADK.ARGGLPPEDA......EKTEDQLKDEYKKI-----AERRVRLGLVLAEIGRKNDVV
TIG_HAEIN/262-413----------L....RNQAAQRF....GGNAQQ.........TAQLPRELFEAE-----ATRRVQVGLLFSEVIKSNELK
TIG_MYCGE/275-440----------L....LKLQQSQA.EQYKIPFEKLLSASNI..TLTELQDRNIKE-----AKENVTFALVMKKIADIEKIK
TIG_HELPY/268-427----------L....FRNALYSM......QAEEVKSLQESQEKAKEKRESFRND-----ATKSVKITFIIDALAKEEKIG
TIG_BUCAI/263-415----------L....YKQYTKQY............QEENSNILEKKYHMSLDSE-----VKKRLYFQIIIEQIILNNKLF
TIG_PASMU/262-413----------L....RGQAAQRF....GGNKEQ.........AAQLPRELFEEQ-----AKRRVQVGLLLAEVIASHELK
TIG_SALTI/262-413----------L....RRQAAQRF....GGNEKQ.........ALELPRELFEEQ-----AKRRVVVGLLLGEVIRTNELK
TIG_STAAW/264-422----------M....VSEFAQRI.QQQGLDLQTYFQISGQ..DETQLREQMKDD-----AEQRVKTNLTLTAIAEAEKIE
TIG_MYCPN/275-440----------L....LRAQKDQA.EQYKIPFERLLAASKL..SLEQLQQRNIKE-----ARDNVTFALVMKRIADVEKIK
TIG_BACSU/264-422----------M....LKEFEQRL.QMQGMNLELYTQFSGQ..DEAALKEQMKED-----AEKRVKSNLTLEAIAKAENLE
TIG_CAMJE/268-427----------Q....MRAAFNTF......SEKEIEELKASKEKYQEKRDSFKEE-----AQKSVKLTFIIDELAKLRKIE
TIG_SYNY3/277-441----------L....VAQTAMEL.ERMGLDVSQLFRQGDD..MLQTLKDNSRPE-----AIANLKTDLMIGAIAKEEKIQ
TIG_STRP6/264-422----------S....VNEFMGNM.QRQGISPEMYFQLTGT..TQEDLHNQYSAE-----ADKRVKTNLVIEAIAKAEGFE
TIG_BUCAP/270-415----------L....RNKFIKEY............KEKQENILKKKYHTNLESK-----AKTRLHIKLIIEKIIRDNKIS
TIG_CHLTE/257-411----------L....LENAKRQV....GGQFPKGF.......DEREFFNAMKPN-----AEKHARWLLISQKIAKENNLE
TIG_CORGL/258-419----------Q....LHQLLGEL.AHDDAALNSLLEAQGT..TREEFDKKNVED-----AEKAVRTQLFLDTLSEVEEPE
TIG_XANAC/258-413----------M....LAQQVEQV.RRSGRDPGQ.........VPADAHQGFMDA-----AAKRVLVGLLVGEVARRNELR
TIG_FUSNN/261-426----------R....LKELEYQL.SMQGFKMDDYLKMMGG..NVETFAAQLAPA-----AEKKVKIDLILDRIAKDNNFE
TIG_THETN/263-423----------S....LRDLDYNL.RLQGLDLNTYLSITGK..TIQDLRKEMWEG-----ALNRVKTQLVIDKIAKVENIE
Q8RPF7_DESHA/157-313----------I....FAEKQKQL..FTSDNPQMLEALLSG..DNRSLHRESLLL-----AEEIIVEDLILKEIARIEKIQ
Q8RPH5_DESHA/154-311----------L....YRQFAEELKTIHGVELINYLMYRKL..SSDELLAECKQE-----SARKILGEAIMDAVIQAEGFR
Q8RPJ3_DESHA/155-300----------T....LAETRQRM..ISSENLTMMSSLLSE..DDEYFYEDCRLL-----TQKTILRQLVLDEIARLEAIG
TIG_ARATH/379-538----------F....YGARLLEIQGNMKLNEDQLASLSSQK.AVNEFLETQRES-----ITNIIKQNIAVGDIFKRENLE
TIG_AGRT5/268-426----------I....WRQINTDL.AQSGKTFADE......DTTEEEAREEYRKL-----AERRVRLGLVLSEIGEKAGVE
TIG_CLOPE/263-425----------M....VRDLEMRL.GQQGLSLEQYYEFTGS..TEDKMKSYMKEN-----AERKVKTDLVMSAVTEAEAIE
TIG_RALSO/273-427----------L....VEMARRDL.EARGMPNVK.........NMPIPAEMFAQQ-----AERRVKLGLVLAEVVKVNALE
TIG_LISMO/264-422----------L....MNHFAQDL.QAQGLTPELYYQFTGQ..TEEAMHAQMEKD-----AEKRVKMNLVLEAIAEAENIE
TIG_BRUME/268-426----------I....WQQINFDL.QQAGRTFEDE......ETTEEAAREEYRKL-----AERRVRLGLVLSEIGEKAGVE
TIG_NOSS1/279-432----------M....LTQTAMRL.SQQGLDVKKLFTQD....IIPQLRERSRPE-----AVERLKRSLGLQEVAKRESIT
TIG_RICCN/261-416----------L..............KSGTDKNEQDESLLKDKSSKEITAYYNKL-----ALRRVRIGLLLAEYAKSKNLQ
TIG_SYNE7/273-427----------M....INETASRL.SGQGMDVRKLFTEE....VLERLRENSKDE-----AEQRLRRTIALGELAKVTETQ
TIG_CLOAB/264-425----------M....LKELESRL.RYQGLDLKSYYEYTNS..SEEKVRDYMKET-----ADKRVRTKLVMEKISEVEKVE
TIG_STRPN/264-422----------S....VNEFLGNL.QRQGINPDMYFQITGT..TQEDLHNQYQAE-----AESRTKTNLVIEAVAKAEGFD
TIG_RHILO/268-427----------I....WAQVTRDL.EAAGRTFADE......ETTEEEARAEYLRL-----AERRVRLGLVLAEIGEKAGVT
TIG_MYCPU/270-429----------I....NEKFNETL.KAQGLKRREYLEMTKL..SEEKVAEQVKKE-----AITKINEYLIFEQIKKAENVT
TIG_MYCLE/258-419----------A....LHDALSGL.GHDEAKFAEVLAERGS..SREEFEAEARSA-----AERDVTRQLLLDVVADDQKIQ
TIG_LACLA/264-422----------A....MNEFLGGM.QQQGISPEMYFQITGT..SEDDLHKQYEAD-----ADKRVRTNLVIEAIAAAENFT
TIG_STRCO/258-420----------R....KHNLEHHQLGQMGLDLEKYLELQGK..TAEEFETETREA-----AVKGIKTQFVLDELVKQEKLN
TIG_PSEAE/262-412----------L....RVQAVQQF....GGNIK..........PDQLPAELFEEQ-----AKRRVVLGLIVAEVVKQHELK
TIG_NEIMA/264-418----------L....ANEMKQNF.VNQGMADAA.........NLDLPLDMFKEQ-----AERRVSLGLILAKLVDENKLE
TIG_BACHD/264-425----------M....TQEFEQRL.QMQGMNLEMYFQFSGQ..TQEQLREQMKED-----AEKRVRVNLTLEAIANQENLE
TIG_VIBCH/262-413----------L....RQQAAQRF....GGNVEA.........AAQLPRELFEEQ-----AKRRVVVGLLLGEVIRTHELK
Q9LAS3_9FIRM/151-307----------I....LVKTRQSI..ISSENLSMMPSLLSE..DDEYFYEDCKIL-----TEKTILRKLILDEIAHLETIG
TIG_XYLFA/259-414----------M....LAKQIEQI.RLSGRDPTG.........IPDDAHIGFMDA-----ACKRVLVGLLVGEIAGRNRLR
TIG_UREPA/274-434----------L....RQQVLSQL.SQYKIELKQYLEFSKK..SEAQFQEDLIRQ-----AKETITLALLVDDIAETQNIV
TIG_OENOE/271-430----------Q....MQTFFNNL.AGQGVKPEMYFQIPNQ..P.GAVKATNDRR-----RTNRVKTNLVLEEIARVEKIN
TIG_DEIRA/249-416----------M....MSEIQDDL.RRQGVQWKEYEAFMQEQGKLDEFEADLTKN-----AETRVRRDLALEQLATDLNAQ
TIG_THEMA/247-403----------A....INRLKREG.........RYEQIVSSYESEEKFREELKER-----ILDDIKRDRVIEVLAQEKGIS
TIG_AZOBR/262-419----------I....WQRLQQEL..QNGTAGEDA......GKPEEELKTEYRGI-----AERRVRLGLLLSEIGRRNDIQ
TIG_CHLPN/272-431----------I....TREKLLNA......RLIQYCSDEELEKRKSELIKEAEED-----ATKALKLLFLTHKIFSDEKLT

PF13623

C6I507_9BACE/4-147VSKAEIQSIINEGVNPLLQQT........P.F.R-NPQTGAFDKDMLKKFL----------------------------
D3HY39_9BACT/4-150VTDTELQDVLKAGTNPMLLQT........PFVNQ-Q..TGRFDAASLQKFL----------------------------
D3II58_9BACT/4-150VTDQEMQNVLNQGTNPMLMQT........PFVNQ-Q..TGRFDASSLKKFL----------------------------
D9RVL8_PREMB/4-150VTEKEIQNVL........NEGTNPMLVQTPFVNQ-Q..TGRFDVNALKQFF----------------------------
D1XVV4_9BACT/4-150VTEQEMQNVLNDGTNPALAQT........PFV.N-Q.QTGRFDVNALKQFI----------------------------
C6YVX2_9GAMM/2-125VSKLALQSAI........FTN........PMF.F-D.KDGKFSADKLKQVV----------------------------

PF13624

B7TX43_PSEFL/1-165FSEAALDQVI--------LQT--------PEF-Q-V.D.GKFNAERFDQVVRQLGYSR---LQFRQMLTQEMLIGQVR-
D3SMV5_THEAH/1-156ASDEEVIDTI--------KSD--------PTF-Q-E.G.GVFSASKYREVLERNNLEP---AQYEEYLKKMLSIQKLV-
B4U8V8_HYDS0/1-151VSDKEVADII--------SQD--------PSF-Q-V.D.GKFNFDRYKAVLAEAGYTP---ETYESYIKKQLTIQKYT-
B5EQ33_ACIF5/1-165VPDAALAKKI--------ESI--------PAF-Q-E.K.GAFSKNLYQKLLAANGMTP---AQFEDMLRESMRLEQLQ-
E6TYN9_BACCJ/1-153VSDEEVAIQL--------QLI--------KEV-.-.....LPSDLTLEESLILQNYTE---DALLAEIKEQLMIERLL-
C7MZH2_SACVD/1-146VDETKVDELI--------EA.--------...-.-S.G.G......VEEAARNIAVEP---SRVRDVARDQLLLEQLG-
A3EPT2_9BACT/1-171VPDAVVVSEV--------SRI--------PFF-Q-EGNPPVFSSKLYTQFLLETHQSA---KDFEQSIREDLLVQRAQ-
C6HWQ2_9BACT/1-170VSDKTVVDEI--------AKI--------PFF-Q-VGNPPVFSKDAYVTFLKETHQSA---QSFERSVRLDVLVQRAQ-
B5YGW7_THEYD/1-157ATDKEVQDAI--------VND--------PRF-M-R.N.GIFQRDIYFQILKLNRLNP---AQYEASLKREITIGKTI-

PF09312

SURA_AROAE/35-152VDEATLERAI-------------------ARIAE-S---NRLTIAQLQAALEKDGVSW---SRFRDNIRTEILLTRLR-
SURA_VIBVY/24-141IDDTRLNQAI-------------------EEIAR-N---NNQTIDELSAAIASEGVSY---EEFREQIRKEMAASEAR-
SURA_RALSO/87-204VSDADVDRAV-------------------ESVAQ-R---NNLSVSQLKSKLAQSGLAY---DKYREDLRQEILLARLR-
SURA_CHRSD/29-146IDDTQLNATV-------------------RGIAE-D---NGMSMDEFADALEEDGMSL---ASMREQVRREMLLRQVQ-
Q1V6U0_VIBAL/24-141IDDNRLNQAI-------------------AEIAR-N---NEQSVEQLAASVESEGLSY---PEFREQIRKEIAASEAR-
Q2BK15_9GAMM/30-147VSDSQLNGAI-------------------ANIAA-Q---NGLSIDQFREALIAEGRDY---NQAREQIRNEMLINSVQ-
Q2BZR3_9GAMM/27-144IDDSQLDKAI-------------------ADVAK-Q---RNMSVDQLRQSLANAGISY---AMFREQMRNDMLASEAR-
SURA_HAHCH/34-151VSDSQLNQTM-------------------QNIAK-Q---NGMTLDQFQQALSEEGVTY---QSAREQIRREMIISRVQ-
SURA_NITMU/36-153VSDAELDQTL-------------------RRIAQ-E---NKMSLQEFDRALAEDGVSF---SKFRDEIRDEIILVRLK-
SURA_NITOC/23-140VGDETLNEAL-------------------GRIAQ-D---NGLTLSQFRNVLEQDGYDF---PAFRENIRKELIISQLH-
SURA_PSEPF/18-135ITDEELNQAV-------------------GTIAQ-R---NNMTPEQFRIALSRDGLSY---EDAREQIRREMVISRVR-
Q3RGI7_XYLFA/33-150VSDDELNQAI-------------------SSIAE-N---NKTSVDGLRQKLVAEGISF---PEFRQSVRDEITVHHLR-
SURA_THIDA/35-152ADPTLVERAL-------------------QRIAA-Q---NKLDMAGLQAALEKEGQTL---DGMRNTIRNELLIARAR-
C1DIW7_AZOVD/32-149IGDEELAQAM-------------------ATIAQ-R---NGLTLEQFQAALARDGLSF---DEAREQVRREMIISRVR-
SURA_VIBF1/27-144IDDTRLEAAL-------------------NDIAK-E---NNMTLAQLQQKTAAQGLPY---ANFREQIRKEIAASEAR-
SURA_SALPA/25-142ITDEQLDQAI-------------------ANIAK-Q---NNMTMDQMRSRLAYDGLNY---STYRNQIRKEMIISEVR-
SURA_METCA/30-147VDDDTLRMAV-------------------SQIAQ-R---NNLTPDQFRRSLAREGIDY---GDFLDQVRSEIAMGRLR-
SURA_YERPS/25-142ITDQALDKAI-------------------ADIAA-Q---NRMTLAQMRSRLAADGLSY---DTYREQIRKEMLTSEVR-
SURA_XANCP/31-148VSDEELNRAI-------------------ASIAQ-Q---NGTSVDGLRQKLAADGMGY---ADFRASVRDEIIVQRLR-

PF05698

TIG_BORBU/272-432VTESDVEDEM-------------------ARQSK.NLG..V.SYEEIKKFYEDQNLIS....YLKDDIKRERAKKKILE
TIG_MYCTU/258-419VGQDDLTERL-------------------VTTSR.QYG..I.EPQQLFGYLQERNQLP....TMFADVRRELAIRAAVE
TIG_RHOCB/265-420VTDAEMTQAV-------------------LAAAR.QYP..G.HEREFFEFVKGNAQMQ...QQIRAPLYEEKVIDFIVA
TIG_TREPA/266-420VSAEEIETEY-------------------VRIAS.KTG..S.KEERVREYYAGEEKRR....ALCEGIRERKLCQKLLG
TIG_CHLTR/273-432ISREELQYMM-------------------DVCSRERFG..GYPPKDISNEMIQELVLV.....ARDRLTYRKAIEAISS
TIG_CAUCR/268-426VTDQELTDAI-------------------MREAR.QYG..A.QAQQVFDMYRQRADLQ...AALRAPIYEDKVVDLIFG
TIG_HAEIN/262-413ADEERAKAMI-------------------ADIAS.AYE....QPAEVVEYYSKNEELM...NNIRNVVLEEQAVDAVLA
TIG_MYCGE/275-440VDNNKIKAEI-------------------ENVIAVEYP..FASDEMKKQLFFNMEQQK...EFVESIIINRLTTTKIVS
TIG_HELPY/268-427VHDNEVFQTL-------------------YYEAM.MTG..Q.NPENLIEQYRKNNMLA....AVKMAMIEDRVLAYLLD
TIG_BUCAI/263-415ADENNIQKLI-------------------KKISS.NYK....NPMEIIKLYNKNKNLK...NTMKNIELERQAMLLLKK
TIG_PASMU/262-413VDEARAKTMI-------------------EEIAS.AYE....QPAEVVEYYSKNKELM...NNIRNVVLEEQAVDAVLA
TIG_SALTI/262-413ADEERVKGLI-------------------EEMAS.AYE....DPKEVIEFYSKNKELM...DNMRNVALEEQAVEAVLA
TIG_STAAW/264-422ATDEDIDKEL-------------------EKMSK.QFN..I.SVEDIKNTL...GNTD....IIKNDVRIQKVIDLLRD
TIG_MYCPN/275-440VDNKKIHSEI-------------------ESIIDVEYP..FVNAELKKQMFHNMEQQK...DFVESIILNRLTTTKIIE
TIG_BACSU/264-422VSDEEVDAEL-------------------TKMAE.AYN..M.PVENIKQAI...GSTD....AMKEDLKVRKAIDFLVE
TIG_CAMJE/268-427VNDQELIQAI-------------------YFEAY.RYG..M.NPKEHLENYKKQGALP....AVKMALIEEKLFNDIFI
TIG_SYNY3/277-441PTEAEVKERC-------------------DELRQ.EFKGEKIDESRLVNFVESSLTES....KVLDLLKEWADVELLPE
TIG_STRP6/264-422ATDSEIEQEI-------------------NDLAT.EYN..M.PADQVRSLL....SAD....MLKHDIAMKKAVEVITS
TIG_BUCAP/270-415VNEEKVDLLI-------------------KKISL.KYK....KPLEIINIYKKNTMLR...KTIKNIELEMQVMQFLIK
TIG_CHLTE/257-411VTDEDIKAFA-------------------EKEAE.KEP..SLTVDQLLNTYLSTEFKD....YIIDTILKEKIYDVIKS
TIG_CORGL/258-419VSQQELTDHI-------------------LFTAQ.SYG..M.DPNQFIGQLQQSGQIA....NLFSDVRRGKALAQAIC
TIG_XANAC/258-413LESKRVSETL-------------------RLIAS.TYE....EPEQVIEMYRNDPQLM...NGLQSRVMEEQVIDWIAE
TIG_FUSNN/261-426ATDEELNQRM-------------------EEIAK.MYG..M.DVPALEEELKKNKNLENFKASVKYDIVMKKAIDEVVK
TIG_THETN/263-423ATEEELENKL-------------------KELAE.SYR..V.NLEEFKKSL.TESQIN....GIKEDIAYYKTIDFIFN
Q8RPF7_DESHA/157-313VEPSEFREAR-------------------EKFLE.SAG....NEQSFRLIFPTDD.......ALQQHLLQEKVLDCLWE
Q8RPH5_DESHA/154-311IPAERLEKEQ-------------------EKLAKNRQG.........DQEFDSVAALK....KAETQLLRRKAMEFLLE
Q8RPJ3_DESHA/155-300VTPDEIQEEK-------------------KRHTP................FPDEE.......AIGQHLIEKKVARLLLE
TIG_ARATH/379-538FSTDELVKEV-------------------ENSIS........EFKKHKQEFDEERVKD....QVQEILEGAKVLEWLKD
TIG_AGRT5/268-426VTEEEMQRAL-------------------FQQLQ.QFP..G.QQKEILDFFRNTPGAS...ASLRAPIFEEKVIDKLLT
TIG_CLOPE/263-425ATEEELKAKA-------------------EEVAK.MYSNGA.ETEKMVDLL.LNAQRA....ALELDVKREKTLKMLFE
TIG_RALSO/273-427AKPEQIKAEI-------------------EEFAK.SYE....DPKEVIRWYYGDQQRL...AEMEAYVLENNVVNFVCD
TIG_LISMO/264-422PTEEAIDEEI-------------------STLAE.KYG..M.EKDAVRAAL...GDMS....ELKSDLKIRKAIDVLLD
TIG_BRUME/268-426VTEEELQRAV-------------------YDQVR.RYP..G.QEKEIYDFLRRTPDAV...ANLRAPIFEEKVVDHLLA
TIG_NOSS1/279-432VTPEEIQARV-------------------TELVQ.QYP.........DEDIDAERLQT....IVENELLSEKIIDWLLA
TIG_RICCN/261-416LEPDDLRKVI-------------------MQQAR.NFP..G.QENMIFDFYKNNPRAI...EGLKGPALEDKAVQYIFN
TIG_SYNE7/273-427VDDEAVKARA-------------------AELLS.NYP........RPQEIDRDRLNT....VVREELLEDKLLEWFEA
TIG_CLOAB/264-425ATEEELKEKA-------------------KEMAQ.QYTN.K.DLDKMAELV.LNSQRS....MIEQDVINGKVIDLLVE
TIG_STRPN/264-422ASEEEIQKEV-------------------EQLAA.DYN..M.EVAQVQNLL....SAD....MLKHDITIKKAVELITS
TIG_RHILO/268-427VSDEELQRGL-------------------FEQVR.RFP..ANQQQEAFEFYRSNPEAL...NALRAPMFEEKVVDHLLG
TIG_MYCPU/270-429ISDDIIEDHY-------------------NIMAK.NYN..I.EVDKIKEFIPVDKLKE......DPNLLNEQVILKLLE
TIG_MYCLE/258-419VGQDDLNERL-------------------LATSQ.QYG..V.DAQQLFGFLRENNRLS....SLVTDARRRLAVAAVVE
TIG_LACLA/264-422TSDEEVKAEI-------------------EDLAG.QYN..M.PVEQVEKLL....PVD....MLKHDIAMKKAVEVIAT
TIG_STRCO/258-420VSQEELTEHL-------------------MRRAA.SSG..M.SPDQFAQAVVEQGQVP....LLVGEVARGKALAAVVE
TIG_PSEAE/262-412ADEGRVREMI-------------------EEMAS.AYQ....EPEQVVAWYFKNEPQL...NEVRSVVLEEQVVDTVLQ
TIG_NEIMA/264-418PTEEQIKAVV-------------------ANFAE.SYE....DPQEVIDWYYAEPSRL...QAPTSLAIESNVVDFVLG
TIG_BACHD/264-425ASDEDVEKEL-------------------EKMAE.MYQ..R.SVDEIKSIFATQGGTD....GIKADLKIQKAVDFLVE
TIG_VIBCH/262-413ADEEKVKALI-------------------TEMAT.AYE....DPSEVVSYYEQNQQLM...NNMRNVALEEQAVDAIIA
Q9LAS3_9FIRM/151-307VTDDEIQEEK-------------------KRLLN.LAA....DQTAFYKQFPDEE.......SIGNNLVEEKXAKLLLE
TIG_XYLFA/259-414LDPMRVTETL-------------------HLIAS.TYE....EPEEVFEMYRNDPKLM...EGVQSLVMEEQVIEWIAD
TIG_UREPA/274-434VSDEEVKERV-------------------AEMAK.LYQ..G.EEQAVIEQLSKNPD......AVKEFLLHKKVVNYLID
TIG_OENOE/271-430PSNEEIDKEI-------------------KSLAS.EYN..I.KESEVEKSV....SAG....MLSHDLKVQQAVELIVN
TIG_DEIRA/249-416VNEAEFNQTL-------------------MNLAQ.ANG..M.NVQQLVQQLGQDGVQSYYISLLRERGLQRALAQLSGE
TIG_THEMA/247-403VNDEELEKEA-------------------EELAP.FWG..I.SPDRAKSLVKARQDLR...EELRWAILKRKVLDLLLQ
TIG_AZOBR/262-419VTQDEINRAL-------------------IAEAR.RFP..G.QERQVFEFFKQNREAL...ENLRAPIFEDKVVDYILD
TIG_CHLPN/272-431ISREELQYMM-------------------DVCSRERFG..QQPPKDISNDTLQELVMS.....ARDRLTYSKAIEHVLR

This alignment is coloured according to the ClustalX colouring scheme:

 
Glycine (G)
 
Proline (P)
 
Small or hydrophobic (A,V,L,I,M,F,W)
 
Hydroxyl or amine amino acids (S,T,N,Q)
 
Charged amino-acids (D,E,R,K)
 
Histidine or tyrosine (H,Y)

For UniProt-based alignments, we also add some additional mark-up to the alignments where appropriate. Active site information is shown as follows:

 
Active site (residue annotated in SwissProt as an active site)
 
Predicted active site (residue aligns in a Pfam alignment with a SwissProt active site)
 
Predicted active site (residue annotated in SwissProt as a potential active site)

Some UniProt sequences can be mapped to protein structures, in which case we also show the secondary structure definition. These lines are shown below the sequence to which they apply and are marked (SS). The meaning of each of the symbols is as follows:

C
Random coil
H
Alpha-helix
G
3(10) helix
I
Pi-helix
E
Hydrogen bonded beta-strand (extended strand)
B
Residue in isolated beta-bridge
T
H-bonded turn (3-turn, 4-turn, or 5-turn)
S
Bend (five-residue bend centered at residue i)
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