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230  structures 114  species 11  interactions 1802  sequences 12  architectures

Clan: Serum_albumin (CL0282)


Serum albumin superfamily Add an annotation

This superfamily includes serum albumin and related families.

This clan contains 2 families and the total number of domains in the clan is 1802. The clan was built by A Bateman.


This clan contains the following 2 member families:

Serum_albumin VitD-bind_III

External database links

Domain organisation

Below is a listing of the unique domain organisations or architectures from this clan. More...

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The table below shows the number of occurrences of each domain throughout the sequence database. More...

Pfam family Num. domains Alignment
Serum_albumin (PF00273) 1671 (92.7%) View
VitD-bind_III (PF09164) 131 (7.3%) View
Total: 2 Total: 1802 Clan alignment

Please note: Clan alignments can be very large and can cause problems for some browsers. Read the note above before viewing.

Family relationships

This diagram shows the relationships between members of this clan. More...

Species distribution

Tree controls


This tree shows the occurrence of the domains in this clan across different species. More...



There are 11 interactions for this clan. More...

Interacting families
Actin Serum_albumin
Ig_2 Serum_albumin
MHC_I Serum_albumin
Serum_albumin Actin
VitD-bind_III Actin


For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between the Pfam families in this clan, the corresponding UniProt entries, and the region of the three-dimensional structures that are available for that sequence.

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