Please note: this site relies heavily on the use of javascript. Without a javascript-enabled browser, this site will not function correctly. Please enable javascript and reload the page, or switch to a different browser.
49  structures 5303  species 3  interactions 9398  sequences 65  architectures

Clan: LigB (CL0283)


LigB-like superfamily Add an annotation

This clan includes the LigB subunit of the aromatic ring opening dioxygenase LigAB [1]. The clan also includes the Memo-like proteins.

This clan contains 2 families and the total number of domains in the clan is 9398. The clan was built by A Bateman.

Literature references

  1. Sugimoto K, Senda T, Aoshima H, Masai E, Fukuda M, Mitsui Y; , Structure Fold Des 1999;7:953-965.: Crystal structure of an aromatic ring opening dioxygenase LigAB, a protocatechuate 4,5-dioxygenase, under aerobic conditions. PUBMED:10467151 EPMC:10467151


This clan contains the following 2 member families:

LigB Memo

External database links

Domain organisation

Below is a listing of the unique domain organisations or architectures from this clan. More...

Loading domain graphics...


The table below shows the number of occurrences of each domain throughout the sequence database. More...

Pfam family Num. domains Alignment
LigB (PF02900) 6679 (71.1%) View
Memo (PF01875) 2719 (28.9%) View
Total: 2 Total: 9398 Clan alignment

Please note: Clan alignments can be very large and can cause problems for some browsers. Read the note above before viewing.

Family relationships

This diagram shows the relationships between members of this clan. More...

Species distribution

Tree controls


This tree shows the occurrence of the domains in this clan across different species. More...



There are 3 interactions for this clan. More...

Interacting families
LigA LigB
LigB LigB
Memo Memo


For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between the Pfam families in this clan, the corresponding UniProt entries, and the region of the three-dimensional structures that are available for that sequence.

Loading structure mapping...