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70  structures 19533  species 15  interactions 48469  sequences 90  architectures

Clan: FBD (CL0289)

Summary

Folate binding domain Add an annotation

This folate binding domain is found in the GCV T protein as well as the sarcosine oxidase gamma subunit [1].

This clan contains 3 families and the total number of domains in the clan is 48469. The clan was built by A Bateman.

Literature references

  1. Ida K, Moriguchi T, Suzuki H; , Biochem Biophys Res Commun. 2005;333:359-366.: Crystal structure of heterotetrameric sarcosine oxidase from Corynebacterium sp. U-96. PUBMED:15946648 EPMC:15946648

Members

This clan contains the following 3 member families:

GCV_T SoxG TrmE_N

External database links

Domain organisation

Below is a listing of the unique domain organisations or architectures from this clan. More...

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Alignments

The table below shows the number of occurrences of each domain throughout the sequence database. More...

Pfam family Num. domains Alignment
GCV_T (PF01571) 29796 (61.5%) View
TrmE_N (PF10396) 17028 (35.1%) View
SoxG (PF04268) 1645 (3.4%) View
Total: 3 Total: 48469 Clan alignment
 

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Family relationships

This diagram shows the relationships between members of this clan. More...

Species distribution

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This tree shows the occurrence of the domains in this clan across different species. More...

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Interactions

There are 15 interactions for this clan. More...

Interacting families
A B
DAO GCV_T
FAD_oxidored SoxG
GCV_T DAO
GCV_H
GCV_T
GCV_T_C
SoxD
SoxG
GCV_T_C GCV_T
MMR_HSR1 TrmE_N
MnmE_helical TrmE_N
SoxG SoxD
TrmE_N MMR_HSR1
MnmE_helical
TrmE_N

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between the Pfam families in this clan, the corresponding UniProt entries, and the region of the three-dimensional structures that are available for that sequence.

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