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0  structures 19896  species 0  interactions 277440  sequences 176  architectures

Clan: LysE (CL0292)


LysE transporter superfamily Add an annotation

This clan includes a diverse range of transporter families [1].

This clan contains 17 families and the total number of domains in the clan is 277440. The clan was built by A Bateman.

Literature references

  1. Vrljic M, Garg J, Bellmann A, Wachi S, Freudl R, Malecki MJ, Sahm H, Kozina VJ, Eggeling L, Saier MH Jr, Eggeling L, Saier MH Jr; , J Mol Microbiol Biotechnol. 1999;1:327-336.: The LysE superfamily: topology of the lysine exporter LysE of Corynebacterium glutamicum, a paradyme for a novel superfamily of transmembrane solute translocators. PUBMED:10943564 EPMC:10943564


This clan contains the following 17 member families:

BacA Cad Colicin_V DsbD DsbD_2 DUF475 HupE_UreJ HupE_UreJ_2 LysE MarC Mntp NicO OFeT_1 SfLAP TauE TerC UPF0016

Domain organisation

Below is a listing of the unique domain organisations or architectures from this clan. More...

Loading domain graphics...


The table below shows the number of occurrences of each domain throughout the sequence database. More...

Pfam family Num. domains Alignment
LysE (PF01810) 65957 (23.8%) View
TauE (PF01925) 51153 (18.4%) View
TerC (PF03741) 31857 (11.5%) View
BacA (PF02673) 20536 (7.4%) View
DsbD (PF02683) 20242 (7.3%) View
Colicin_V (PF02674) 17424 (6.3%) View
NicO (PF03824) 16243 (5.9%) View
MarC (PF01914) 16122 (5.8%) View
UPF0016 (PF01169) 10232 (3.7%) View
Mntp (PF02659) 7674 (2.8%) View
SfLAP (PF11139) 6004 (2.2%) View
Cad (PF03596) 4508 (1.6%) View
DUF475 (PF04332) 3303 (1.2%) View
DsbD_2 (PF13386) 3052 (1.1%) View
HupE_UreJ (PF04955) 1889 (0.7%) View
HupE_UreJ_2 (PF13795) 1175 (0.4%) View
OFeT_1 (PF16955) 69 (0.0%) View
Total: 17 Total: 277440 Clan alignment

Please note: Clan alignments can be very large and can cause problems for some browsers. Read the note above before viewing.

Family relationships

This diagram shows the relationships between members of this clan. More...

Species distribution

Tree controls


This tree shows the occurrence of the domains in this clan across different species. More...