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792  structures 21223  species 11  interactions 232730  sequences 810  architectures

Clan: GroES (CL0296)


GroES-like superfamily Add an annotation

This superfamily includes the GroES protein as well as the N-terminal GroES-like domain from Alcohol dehydrogenase.

This clan contains 3 families and the total number of domains in the clan is 232730. The clan was built by A Bateman.

Literature references

  1. Taneja B, Mande SC; , Protein Eng 1999;12:815-818.: Conserved structural features and sequence patterns in the GroES fold family. PUBMED:10556240 EPMC:10556240
  2. Murzin AG; , Curr Opin Struct Biol 1996;6:386-394.: Structural classification of proteins: new superfamilies. PUBMED:8804825 EPMC:8804825


This clan contains the following 3 member families:

ADH_N ADH_N_2 Cpn10

External database links

Domain organisation

Below is a listing of the unique domain organisations or architectures from this clan. More...

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The table below shows the number of occurrences of each domain throughout the sequence database. More...

Pfam family Num. domains Alignment
ADH_N (PF08240) 195409 (84.0%) View
Cpn10 (PF00166) 21785 (9.4%) View
ADH_N_2 (PF16884) 15536 (6.7%) View
Total: 3 Total: 232730 Clan alignment

Please note: Clan alignments can be very large and can cause problems for some browsers. Read the note above before viewing.

Family relationships

This diagram shows the relationships between members of this clan. More...

Species distribution

Tree controls


This tree shows the occurrence of the domains in this clan across different species. More...



There are 11 interactions for this clan. More...

Interacting families
ADH_N_assoc ADH_N
ADH_zinc_N ADH_N
ADH_zinc_N_2 ADH_N
Cpn10 Cpn10
Cpn60_TCP1 Cpn10


For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between the Pfam families in this clan, the corresponding UniProt entries, and the region of the three-dimensional structures that are available for that sequence.

Loading structure mapping...