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565  structures 20395  species 33  interactions 565160  sequences 4997  architectures

Clan: CheY (CL0304)

Summary

CheY-like superfamily Add an annotation

This clan includes the CheY-like response regulators from bacteria [1-2].

This clan contains 4 families and the total number of domains in the clan is 565160. The clan was built by A Bateman.

Literature references

  1. Pao GM, Saier MH; , J Mol Evol 1995;40:136-154.: Response regulators of bacterial signal transduction systems: selective domain shuffling during evolution. PUBMED:7699720 EPMC:7699720
  2. Galperin MY; , J Bacteriol. 2006;188:4169-4182.: Structural classification of bacterial response regulators: diversity of output domains and domain combinations. PUBMED:16740923 EPMC:16740923

Members

This clan contains the following 4 member families:

FleQ OKR_DC_1_N Response_reg TadZ_N

External database links

Domain organisation

Below is a listing of the unique domain organisations or architectures from this clan. More...

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Alignments

The table below shows the number of occurrences of each domain throughout the sequence database. More...

Pfam family Num. domains Alignment
Response_reg (PF00072) 547587 (96.9%) View
OKR_DC_1_N (PF03709) 16166 (2.9%) View
FleQ (PF06490) 989 (0.2%) View
TadZ_N (PF16968) 418 (0.1%) View
Total: 4 Total: 565160 Clan alignment
 

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Family relationships

This diagram shows the relationships between members of this clan. More...

Species distribution

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This tree shows the occurrence of the domains in this clan across different species. More...

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Interactions

There are 33 interactions for this clan. More...

Interacting families
A B
CheB_methylest Response_reg
CheY-binding Response_reg
ECH_1 Response_reg
GerE Response_reg
HATPase_c Response_reg
HisKA Response_reg
Hpt Response_reg
OKR_DC_1 OKR_DC_1_N
OKR_DC_1_N OKR_DC_1
OKR_DC_1_N
PAS Response_reg
RcsC Response_reg
Response_reg ANTAR
CheB_methylest
CheC
CheY-binding
CheZ
EAL
GerE
GGDEF
HATPase_c
His_biosynth
HisKA
Hpt
HTH_8
P2
Response_reg
Sigma54_activat
Trans_reg_C
Sigma54_activat Response_reg
SPOB_a Response_reg
SPOB_ab Response_reg
TPR_12 Response_reg

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between the Pfam families in this clan, the corresponding UniProt entries, and the region of the three-dimensional structures that are available for that sequence.

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