Sequence alignment for CL0308

PF03916

O30284_ARCFU/4-302LNPQHYYLLQQPWWGILIAF.YLFLG..GLGAM..AFC---ISFYF....WRQKGS..QS..........L.VVGGSLL.
C9MGA2_HAEIF/6-321PVPFHTPNL...VWDYTIAI.YLFLL..GISSG..AVQ---LAIAY....KRSNKL..ENL..SQN...WI.IRSGVIL.
Q9CPL1_PASMU/2-319NSPFHFPSL...VWDHTIAV.YLFLL..GISAG..ATM---LAVLL....KRA.GL..AGAEPSNN...HV.IRCTAFL.
I0HUM7_RUBGI/48-336VVTGMSDQV...SWGFYIAN.FAFLV..GIAAA..AVL---LVIPA....YLFHR.....G..DVK...QV.VIFGEAL.
PSRC_WOLSU/6-317GSIEQYNTV...VWHWPIAV.YLFLA..GLSAG..AII---SAIII....KWMKGN..ESS..PWD...GI.IKAGALI.
C3NJI3_SULIN/39-347TEPND.EPI...PWGLLVIG.YMFFG..VIGTG..VST---YNSLY....ELFNKNHPEKN..PFK...NISLRNEWI..
Q9Y8M5_AERPE/24-334D..FKAGGA...IWGVLLVV.YPLMT..GILAG.SYLV---SALAYGFGVKRLYRV..AGL..S.....LI.ISVGLLLS
HMEB_ARCFU/40-332GLNGLSNRV...PWGIVNAG.IPYFI..GLSAG..SLI---VSALA....GVFNIK..KYK..VFS...RI....AAYM.
A0A021WU34_SALET/9-291EVLAHPQDI...SW.LPWAVQYFFFI..GIAAC..AAL---FACYL....HWRKKD..AAT..EENRALLI.AITCAIT.
O30063_ARCFU/31-338.VTNMRNPF...SWGLYIAM.WAFFV..GTAAGGLVVS---SAIYI......FGAR..EFK..PIA...PV.ASTTAFI.
D3RSP2_ALLVD/43-337WVSGMNNSV...VWGTPHVF.AVFLI..IAASG..ALN---IASIG....TVFKKP..IYK..PLG...RL...SGLL..
B0R490_HALS3/45-360GLIETGMRN...VFSWGLYI.MLFVLFVGLSAG..GLI---LSSAP....KFFHSQ..R.....YE...GF.ARLGVLV.
A0A017J532_ECOLX/4-318TSAFHFESL...VWDWPIAI.YLFLI..GISAG..LVT---LAVLL....RRFYPQ..AGG..ADS...TL.LRTTLIV.

PF04976

YNFH_ECOLI/1-274MGNG--------WHEWPLVI-FTVLG--QCVVG--ALI...VSGIG----WFAAKN--DAD--.RQ---R..IVRGMFF-
O67278_AQUAE/1-314MH..--------.PPISLIF-FFLTA--GTSIG--LFIFTYFIEFL----TLFGKG--QGL--PKE---V..VLVSGVI-
Q9CK77_PASMU/1-272MN.G--------LHELPLVI-FTVLA--QSVVG--AFL...LFAIV----LFTTED--KHY--.RA---Y..VHKAMFV-
Q98BE5_RHILO/1-311MH..--------.PAFSVVF-FTTAT--GAGYG--......LLALL----GVLGGF--QII--PPD---FWLGLVGMGL-
DMSC_ECOLI/1-277MGSG--------WHEWPLMI-FTVFG--QCVAG--GFI...VLALA----LLKGDL--RAE--AQQ---R..VIACMFG-
DMSC_HAEIN/1-269MNTG--------LYELPLVF-FTVLA--QSAVG--AWL...VFTFV----LLNEKN--TKS--.RT---Y..IHKVMFV-

PF14589

E8PMP4_THESS/2-252-TEFYGLPNAGEFWHWTNLL-HFILV--GLAGG--MAF---LTALL----HLKGHP--EAR--------RYTLWALGLI-
E4U7K8_OCEP5/2-264-TTFYGLPGAEAFWHWTTLV-HFLLV--ALAGG--TAF---YTAVL----GIRRAA--SAR--------GLAWLALAFI-
Q72LA6_THET2/2-252-AEFYGLPNAQEFWHWTNAL-HFVLV--GLAGG--VAL---LAALL----HLKGDA--EAR--------RYTLYALMLI-

PF03916

O30284_ARCFU/4-302GLIAVL.I.GTLFLILDLG.HPE.RFYLVL.LSPRLNP..S...SWIV..I.GS..TLLS..AFMLFAA...LFVAPM..
C9MGA2_HAEIF/6-321GSVPTL.I.GLTLLIFHLT.RPW.TFWKLM.F..NYQF..N...SVMS..M.GV..MLFQ..IYMLFLV...IWGVVIFK
Q9CPL1_PASMU/2-319APLSLI.I.GLVILIFHLT.KPW.TFWYLM.F..NYST..T...SIMS..M.GV..MLFQ..AYMLFLL...VWLAIIFH
I0HUM7_RUBGI/48-336AVAAVV.A.AMLFVTVDIG.RPE.RIWHMLPV..VGRF..N...WPLS..M.......LA..WDVVVLV...GYL.....
PSRC_WOLSU/6-317APLTIG.A.GLLLLIFDLT.RPL.HFWKLL.I..FYNF..S...SVMT..L.GV..LALF..AYFPVVL...IFLLGVFK
C3NJI3_SULIN/39-347.ALTVL.I.PGWIMVFASTYKPG.E..AVY.I..YTSFRDT...SRIA..WNGL..LYAL..VGIGIIL...EILALIGE
Q9Y8M5_AERPE/24-334APIFPM.A........DLK.QPQRAFEIFL.R..PHVI..P...SDAY..P.GVSPMAFFGILYIPLLVVALLNLIFVYR
HMEB_ARCFU/40-332AAAWII.A.AILSIALDIG.KLY.HFMNAV.R..YFNP..T...SIFS..W.NA..FLYS..SYFVICS...IYLLVQFE
A0A021WU34_SALET/9-291APLALT.A.DL.....HQTARVW.HF.........YAW..PTPWSWMP..W.GA..LFLP..LFTGFLA...LW......
O30063_ARCFU/31-338..FAVG.A..MVMVLPDLG.RVD.RILNMF.L..YPNF..S...SLLP..W.DL..IVLS..TYAFLSA...IYTYVLLM
D3RSP2_ALLVD/43-337.AVAML.MGGLLVLVMDLG.RPE.RLIVAM.T..NYNF..S...SIFA..W.NI..FLYT..GFMAIVI...AYLWSMAD
B0R490_HALS3/45-360SLGCIIVA.GLLIL.PDIG.RPD.RIYQFV.T..SPDF..R...SPMVWDF.GI..VMLY..GALNVWY...LWLLT..R
A0A017J532_ECOLX/4-318GPGAVI.L.GLLILVFHLT.RPW.TFWKLM.F..HYSF..T...SVMS..M.GV..MLFQ..LYMVVLV...LWLAKIFE

PF04976

YNFH_ECOLI/1-274-LWLLMGV-GFIASVMHLG-SPL-RAFNSL-N--RIGA------SGLS----NE--IAAGSIFFAVGGL---WWLVAVIG
O67278_AQUAE/1-314-SLILIGA-GAIGASFHLG-HKL-RAWKAI-K--RFNT------SWLS----RE--AVFSGA.YGFTLL---IYLVLKYF
Q9CK77_PASMU/1-272-LLALLGI-GFIASITHLG-SPL-RAFNAL-N--RVGE------SMLS----NE--IATGALFFALAGI---YWLFAILD
Q98BE5_RHILO/1-311-ALGLIVA-GLLSSTGHLG-RPE-RAWRAF-S--QWRS------SWLS----RE--GVASVITFIPAGL---FGLGWVFL
DMSC_ECOLI/1-277-LWVLMGI-GFIASMLHLG-SPM-RAFNSL-N--RVGA------SALS----NE--IASGSIFFAVGGI---GWLLAMLK
DMSC_HAEIN/1-269-ILALLGI-GFIASIMHLG-LPI-RAFNSL-N--RVGS------SMMS----NE--IAAGAIFFTLAGF---YWLIAILG

PF14589

E8PMP4_THESS/2-252-ALDLFVLWAESPARFRFT-----HVWLFL----SFHP--TSPIWWGS--W-GL------ALSFVSAGL---LYLGKGPS
E4U7K8_OCEP5/2-264-VLDLFMLWAESPARFRFS-----HVWLFL----SFEP--ASAIWWGA--W-GL------ATSALMLLL---LALGLGPA
Q72LA6_THET2/2-252-ALDLFILWAESPARFRFT-----HIWLFL----SFHP--TSPIWWGA--W-GL------GLGFLTGGL---LYLGKGSQ

PF03916

O30284_ARCFU/4-302....LRWFK.....WV.P...............WAK...........S...........EAAIR..AFGWLA.FITGIGV
C9MGA2_HAEIF/6-321K..EIEALINR...FI.PK..........LQ.FVMK....LIGI...A...........ERIVS..PVEVIL.FILAAVL
Q9CPL1_PASMU/2-319Q..LVATLIEQ...YAKP...........LR.FVNK....LIAF...A...........AKFTG..LIEIIL.IILSVLL
I0HUM7_RUBGI/48-336....LLNLG......L.PA..........YV.LHAR....WRGE...E...........PVTARYFPVVIVA.IFWAVSI
PSRC_WOLSU/6-317K..ELCDEG........P...........FG.FLAP....LANI...A...........YSMAR..PLEIVT.FVLAIGV
C3NJI3_SULIN/39-347KRREYKDPISR...LL.AW..........LS.SKSV....LILI...V..................GYAILMELILDANL
Q9Y8M5_AERPE/24-334A..DMAAKA........EA..........TGNIIYR....IVSL...GRGYSREDVERDRRVVK..ILSIIG.VILAILF
HMEB_ARCFU/40-332.....EMEK......................................A...........TRFMA..GLAVFW....AVLV
A0A021WU34_SALET/9-291....FLAQQ........................IKR....LFNK...S...........YNVTK..WLALAS.ALCAVGL
O30063_ARCFU/31-338P..RIAERG.........V..........LG.FLKKDATDLESLRQKS...........EKYAK..VLAPIA.LPFAILI
D3RSP2_ALLVD/43-337R..QGGPFN......Y.P...........IG.ILAL....VWRL...A...........................LTTGT
B0R490_HALS3/45-360R..DLAARGSRLSLWV.SDSAAGRDRDRTLM.FWTA....VCAL...P...........AAVA....LHSVTGWIFATQV
A0A017J532_ECOLX/4-318H..DLLALQQR...WL.PK..........LG.IVQK....VLSL...L...........TPVHR..GLETLM.LVLAVLL

PF04976

YNFH_ECOLI/1-274K----------------------------MPQALGK------------------------------LWLLFS-MALGVIF
O67278_AQUAE/1-314E----------------------------VSPFLEH------------------------------TFGIIT-WILGILS
Q9CK77_PASMU/1-272K----------------------------LPKAFGR------------------------------FLLVCA-SAMGLIF
Q98BE5_RHILO/1-311G----------------------------RTGGWAA------------------------------IAGLLA-AIGATVT
DMSC_ECOLI/1-277K----------------------------LSPALRT------------------------------LWLIVT-MVLGVIF
DMSC_HAEIN/1-269K----------------------------MPVSLGN------------------------------VWRIVT-ALIGILF

PF14589

E8PMP4_THESS/2-252K-----------------------------------------------------------------PLAWGL-LAFSLVA
E4U7K8_OCEP5/2-264R-----------------------------------------------------------------FWAGVL-ALTSAVV
Q72LA6_THET2/2-252R-----------------------------------------------------------------ALAWAL-LVFSLVA

PF03916

O30284_ARCFU/4-302AAYTGILIGIVFNIPFWNAPALPV.IFMISALSTG...LAS.LILLMLV.VDR....EAH.EIHVMAKTDGFV.MIF..E
C9MGA2_HAEIF/6-321GAYTGFLLSALISYPMLNNPVLPA.LFLASGTSSG...IAA.TFLIILI.AGKLKG.DSH.ESHFIHKFEVPI.MVT..E
Q9CPL1_PASMU/2-319GAYTGFLLSALISYPMLNNPVLPI.LFLASGTSSG...IAA.LIFCTLL.FTKEDT.HSP.ALGFLHKFELPV.VLM..E
I0HUM7_RUBGI/48-336HTVTAFLFSANAGRPLWHSALLAP.RFIASAFASGPALIIV.ALLALRR.WGGLAV.KQT.VIDLL.....AV.VMT..V
PSRC_WOLSU/6-317GAYTGFLLSAMYSYPLLNTPILPL.LFLASGISAG...ISG.NLLIGLL.FFGKST.KGE.NVGYLHGLDFKV.ILF..E
C3NJI3_SULIN/39-347GSVFGYLSTWVYEF....GPFMSM.LFVILSFYSG...IAMLSFMTPLYNRFRKVK.EDP.NSLSIH..EMYK.ILG..R
Q9Y8M5_AERPE/24-334HGYFDILLASIKSRILWVDPSLPI.RLLASAVFSG...AAL.VTVAYYI.AARFSPGESI.DAGTMKTLSLIM.LFG..L
HMEB_ARCFU/40-332HSGTGAIYSFVYSKELYHSALTPP.MFIVCAITSG...L.G.LLLANLY.FTFRFT.KRELDPKLIRGL.....ALI..F
A0A021WU34_SALET/9-291LIYTGREVSVVLARPIWFSYAFPVAMFL.....SA...LQA.FFALMIV.AARR.......DSVRLPKILWGQ.IWTLAA
O30063_ARCFU/31-338HTVTAWVLATQLSRPWWYGGLLAP.TFIAAAIATG...PAV.VILASLF.VYGYED.RLK.NA...YRLLGKISAAS..S
D3RSP2_ALLVD/43-337GSIFGFLV.ARQAY...DAAILGP.MFVALSFAYG...LAV.FMLV..L.MFGFEE.EGR.PIG.......PR.MMR..R
B0R490_HALS3/45-360G..RGDWFSPL.........VAPV..FIAKALVSG...LGL.LLVVSIL.ADRFTA.FTA.DRGELTSLGKLL.GIF..L
A0A017J532_ECOLX/4-318GAYTGFLLSALKSYPFLNNPILPV.LFLFSGISSG...AAV.ALIAMAI.RQRSNP.HST.EAQFVHRMEIPV.VWG..E

PF04976

YNFH_ECOLI/1-274VWMMTCVYQ.IDTVPTWHNGYTTL-AFFLTVLLSG-------PILAAAI-LRAARV..TF-NTTPFAIISVLA-......
O67278_AQUAE/1-314GFSTAMIYASNKFVLEWNTGITVI-YYLLMYLMLG-------SSAFTII-SYFYNLPYTG-TFLFLTFLFVLL-GLGFRI
Q9CK77_PASMU/1-272MYMMNKVYH.ISTVPTWHTSFTTW-GFYLTIILAG-------FTLGYGL-LHSERPD.AK-VVSWVPTLVSIT-......
Q98BE5_RHILO/1-311VCTTGMIYASLKPIAQWHSHYTLP-AYLIFAAMTG-------SVLLNAL-LQGFGVA.SV-AVLALSLLATLA-GWGWKL
DMSC_ECOLI/1-277VWMMVRVYNSIDTVPTWYSIWTPM-GFFLTMFMGG-------PLLGYLL-LSLAGVD.GW-AMRLLPAISVLA-......
DMSC_HAEIN/1-269MYVMNQVYH.ITSIPTWNNALTSW-SFYLTVVLGG-------LTLSYAL-LIPNKQR.EY-QLQHLPSLFAIG-......

PF14589

E8PMP4_THESS/2-252LAYPGMALAVNLNRPLWNALLAGL--FPLTALVLG---LGVAVLMKSSWALYP.LRILLG-ASLFLAFLYPFT-------
E4U7K8_OCEP5/2-264LAYPGYALAANAARPLWDHLLLAF--FPASGLLLA---LAVLVWLRPAEEAAPWLQVAAL-ASLALAALYPVA-------
Q72LA6_THET2/2-252LSYPGLALAVNLNRPLWNGLMAGL--FPLTALVLA---LGLAALLKSPWALFP.LRVLAG-ASLLLALLYPLT-------

PF03916

O30284_ARCFU/4-302LIVLS......I....FLL.I..RSY.......GPVAA..IESVNT...V..........LFG.WL...A......PYFV
C9MGA2_HAEIF/6-321LGLIV......C....FFV.G..LHF.......GGGQK..TVALHN...A..........LSG.FW...G......VVFW
Q9CPL1_PASMU/2-319IFLLA......A....FFI.G..LYL.......GGGQK..TVAFET...A..........LLGGFW...A......HVFW
I0HUM7_RUBGI/48-336ALQIS......L....FFV.G..VEL.......FTDFY..NETTHA...A..........SMR.............YLF.
PSRC_WOLSU/6-317AFLLF......I....LFV.G..MYY.......QGGST..AEVAKA...A..........LTTGGL...A......SLFW
C3NJI3_SULIN/39-347DGVLA......T....IAV.G..FSLLWWLWLTATNQQ..TSAWAE...L..........MISGPY...S......VVFL
Q9Y8M5_AERPE/24-334AAALITEITSEI....LRV.G..YYL.......LPGEG..IEYYES..............LRG.............SMF.
HMEB_ARCFU/40-332AGLMM......V....LGY.F..LAV.......EGLEKGYIPALHE...A..........VQFVFL...TPTSGVFWSFW
A0A021WU34_SALET/9-291LGLVV......A....MWVSG..DTL.......SGTAI..RQWITV...A..........LSA.............KYYA
O30063_ARCFU/31-338AALLF......MYYNDFLV.R..YWW.......GEGLE..YEALAI...V..........FRD.YL...H......IHF.
D3RSP2_ALLVD/43-337LRNLL......A....LFI.GIALYF.......TLVYH..LTNLYM...AKNDSLEHWLLLSGGIY...T......FLFW
B0R490_HALS3/45-360AFHVV......Y....L......LAA.......ERLPH..AWAHHFGFWA..........ITSNFLIGDT......VYFW
A0A017J532_ECOLX/4-318IFLLV......A....FFV.G..LAL.......GDDGK..VRALVA...A..........LGGGFW...T......WWFW

PF04976

YNFH_ECOLI/1-274...........L----IAC-AGVIVL-------QGLSLASIHSSVQQASA----------LVPDY.........A-SLQV
O67278_AQUAE/1-314AFNVRQFYIKRP----TLN-EALNLP-------HNRSIRVIDKSSTTDNY----------CTTEFYYAKGKQMLP-TFIP
Q9CK77_PASMU/1-272...........T----LVA-AIVIIY-------QGFALSTVVTSAQKATA----------LVPDF.........A-TLSA
Q98BE5_RHILO/1-311ATWRYNDRLKIS----TTA-NTATGL-------AGGTVRSLEWPHTEENY----------LLKEMGFRIARKHSA-KLRR
DMSC_ECOLI/1-277...........L----VVS-GVVSVM-------QGAELATIHSSVQQAAA----------LVPDY.........G-ALMS
DMSC_HAEIN/1-269...........V----SLV-AIVAIY-------QGFNLHNIHSAIQNAAD----------LVPNY.........A-IMTV

PF14589

E8PMP4_THESS/2-252----------------LT.-.------------.LEAR..GHLWEE------------------------------GGVL
E4U7K8_OCEP5/2-264----------------LAS-G------------GADARLAFALWLR------------------------------G...
Q72LA6_THET2/2-252----------------LP.-.------------.PEAR..GHLLEE------------------------------AGFW

PF03916

O30284_ARCFU/4-302GGVLLMGLAIPIMLI.FGYEVKR...PGVTAVTVISAIFVLVGGALLRYVVLEAG----ILQ.IP
C9MGA2_HAEIF/6-321VGVLIIGILIPLIAN.M..FVNDRLKYNRNFI.ILVSIFDLIGVFCLRFFILYAG----QLT.VA
Q9CPL1_PASMU/2-319IGVVGIGLVLPLLLNGI..ATPQ.LKHRKGFM.LLVACLGLIGVLCLRFFILYAG----QMT.LA
I0HUM7_RUBGI/48-336FGLAGAG.....KLQ.P..WIWTALALNVVAV.VILSIHPLR..RTPRLLVLACG----LVF.LG
PSRC_WOLSU/6-317LGVAGMGLALPVVLN.V..ALPHGIKHSSGFV.MLNALIVLAGVMALRFYILYAG----QTF.VG
C3NJI3_SULIN/39-347IGGVLVGVIIPIILY.G..LVYK..RGSSHML.VTSSIFTLLGMFSI........----.IT.IA
Q9Y8M5_AERPE/24-334IDNAYYILALILLVS.L..LIPR.VRENIHSV...AAIAALA.............----..I.VA
HMEB_ARCFU/40-332LLV.IFGIAIPII...I..VLNPKTGYDLRWI.TFAGILHAALVFAERFYLIIPG----QVF.PE
A0A021WU34_SALET/9-291VGWVALWVCTLLFCS.L..ALRHPLSQLRRVL.LVLSALALCWLM..RWTLLIQV----Q.T.VP
O30063_ARCFU/31-338LEVLFI.LFSAIVLA.K..ATTR......ARL.IIGSVSVNVGVLLHRFLLMPPA----YNV.FA
D3RSP2_ALLVD/43-337VGWILVGSLAPMWI..L..YHPV.LSQKREWI.IGACTLVIVGGFSAMYVIIIGS----QAFPIA
B0R490_HALS3/45-360L.WTGLGGAVPLLL..L..ATPS.LRRRTAVI.FTASVLAVFGTLFEGIRLVFTG----YQR.VN
A0A017J532_ECOLX/4-318LGVAGLGLIVPMLLK.P..WVNR..SSGIPAV.LAACGASLVGVLMLRFFILYAG----QLT.VA

PF04976

YNFH_ECOLI/1-274WRVVLLCAGLGCWLC----PLIRRREPHVAGL.ILGLILILGGEMIGR...........VLFYGL
O67278_AQUAE/1-314LAYLFTFVIPLFLLI----YIYVTDVVNLPLL.VLIYLSILAGSAIERWCFFVEGNHVQNLFYGL
Q9CK77_PASMU/1-272LRFVLLGLAIACLFY----VLH..KPASWMSK.LCAVLLVFAAEMIGR...........TLFYGL
Q98BE5_RHILO/1-311IAQALAFSLPVLLLA----ATFALPWPFAAIPSVLAAIIQFAGMLVERWLFFAEAKHTVTLYYCR
DMSC_ECOLI/1-277WRIVLLAVALCLWIA----PQLKGYQPAVPLL.SVSFILLLAGELIGR...........GVFYGL
DMSC_HAEIN/1-269TRLCLLSIVAFLLF.----.....RVKNIGLL.GISVLLTLVAEGIGR...........VLFYGL

PF14589

E8PMP4_THESS/2-252YGLFLALG....LGA----FGKESLA-------PWAAFLAAAG...LRALLVAVGQW--QGL..G
E4U7K8_OCEP5/2-264WGWFLLGGGLLFLAA----FLARRAP-------ALAGACALAGAFVLRSWIVEQGQH--SFFVHG
Q72LA6_THET2/2-252YGLFLLLG....LGT----FWQERLA-------PWAGLLAAAG...LRALLVLAGQW--QGL..G

This alignment is coloured according to the ClustalX colouring scheme:

 
Glycine (G)
 
Proline (P)
 
Small or hydrophobic (C,A,V,L,I,M,F,W)
 
Hydroxyl or amine amino acids (S,T,N,Q)
 
Charged amino-acids (D,E,R,K)
 
Histidine or tyrosine (H,Y)

For UniProt-based alignments, we also add some additional mark-up to the alignments where appropriate. Active site information is shown as follows:

 
Active site (residue annotated in SwissProt as an active site)
 
Predicted active site (residue aligns in a Pfam alignment with a SwissProt active site)
 
Predicted active site (residue annotated in SwissProt as a potential active site)

Some UniProt sequences can be mapped to protein structures, in which case we also show the secondary structure definition. These lines are shown below the sequence to which they apply and are marked (SS). The meaning of each of the symbols is as follows:

C
Random coil
H
Alpha-helix
G
3(10) helix
I
Pi-helix
E
Hydrogen bonded beta-strand (extended strand)
B
Residue in isolated beta-bridge
T
H-bonded turn (3-turn, 4-turn, or 5-turn)
S
Bend (five-residue bend centered at residue i)
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