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43  structures 6898  species 0  interactions 30726  sequences 255  architectures

Clan: Gx_transp (CL0315)


Gx transporter superfamily Add an annotation

This superfamily includes a wide range of transporters that contain many conserved glycine residues in the presumed transmembrane regions.

This clan contains 13 families and the total number of domains in the clan is 30726. The clan was built by A Bateman.


This clan contains the following 13 member families:

5TM-5TMR_LYT BioY CbiM DUF6580 ECF-ribofla_trS ECF_trnsprt Hpre_diP_synt_I MreD QueT Thia_YuaJ ThiW TrpP Vut_1

Domain organisation

Below is a listing of the unique domain organisations or architectures from this clan. More...

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The table below shows the number of occurrences of each domain throughout the sequence database. More...

Pfam family Num. domains Alignment
BioY (PF02632) 4982 (16.2%) View
Vut_1 (PF02592) 4371 (14.2%) View
ECF_trnsprt (PF12822) 4334 (14.1%) View
MreD (PF04093) 3928 (12.8%) View
CbiM (PF01891) 3367 (11.0%) View
ECF-ribofla_trS (PF07155) 2492 (8.1%) View
5TM-5TMR_LYT (PF07694) 2278 (7.4%) View
QueT (PF06177) 1197 (3.9%) View
Hpre_diP_synt_I (PF07456) 1173 (3.8%) View
Thia_YuaJ (PF09515) 1048 (3.4%) View
ThiW (PF09512) 618 (2.0%) View
DUF6580 (PF20221) 542 (1.8%) View
TrpP (PF17099) 396 (1.3%) View
Total: 13 Total: 30726 Clan alignment

Please note: Clan alignments can be very large and can cause problems for some browsers. Read the note above before viewing.

Family relationships

This diagram shows the relationships between members of this clan. More...

Species distribution

Tree controls


This tree shows the occurrence of the domains in this clan across different species. More...



For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between the Pfam families in this clan, the corresponding UniProt entries, and the region of the three-dimensional structures that are available for that sequence.

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