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4  structures 4338  species 0  interactions 23854  sequences 132  architectures

Clan: Gx_transp (CL0315)


Gx transporter superfamily Add an annotation

This superfamily includes a wide range of transporters that contain many conserved glycine residues in the presumed transmembrane regions.

This clan contains 12 families and the total number of domains in the clan is 23854. The clan was built by A Bateman.


This clan contains the following 12 member families:

5TM-5TMR_LYT Bac_export_3 BioY CbiM DUF2232 DUF3816 ECF-ribofla_trS Hpre_diP_synt_I MreD QueT Thia_YuaJ ThiW

Domain organisation

Below is a listing of the unique domain organisations or architectures from this clan. More...

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The table below shows the number of occurrences of each domain throughout the sequence database. More...

Pfam family Num. domains Alignment
DUF3816 (PF12822) 3851 (16.1%) View
Bac_export_3 (PF01313) 3289 (13.8%) View
5TM-5TMR_LYT (PF07694) 2704 (11.3%) View
MreD (PF04093) 2682 (11.2%) View
BioY (PF02632) 2666 (11.2%) View
ECF-ribofla_trS (PF07155) 2634 (11.0%) View
CbiM (PF01891) 1775 (7.4%) View
QueT (PF06177) 1266 (5.3%) View
DUF2232 (PF09991) 942 (3.9%) View
ThiW (PF09512) 735 (3.1%) View
Thia_YuaJ (PF09515) 674 (2.8%) View
Hpre_diP_synt_I (PF07456) 636 (2.7%) View
Total: 12 Total: 23854 Clan alignment

Please note: Clan alignments can be very large and can cause problems for some browsers. Read the note above before viewing.

Family relationships

This diagram shows the relationships between members of this clan. More...

Species distribution

Tree controls


This tree shows the occurrence of the domains in this clan across different species. More...



For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between the Pfam families in this clan, the corresponding UniProt entries, and the region of the three-dimensional structures that are available for that sequence.

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