Sequence alignment for CL0322

PF12349

A1CTG5_ASPCL/632-787--------------------------------------------------------------------------------
A1Z6J2_DROME/390-543--------------------------------------------------------------------------------
PTC2_MOUSE/418-570--------------------------------------------------------------------------------
A4S8G2_OSTLU/258-409--------------------------------------------------------------------------------
A5E1Z8_LODEL/460-615--------------------------------------------------------------------------------
A7RI14_NEMVE/240-393--------------------------------------------------------------------------------
A7RNK5_NEMVE/879-1035--------------------------------------------------------------------------------
A7S0G1_NEMVE/641-795--------------------------------------------------------------------------------
NPC1_HUMAN/649-803--------------------------------------------------------------------------------
SCAP_SCHPO/257-410--------------------------------------------------------------------------------
P91346_CAEEL/298-449--------------------------------------------------------------------------------
PTR9_CAEEL/288-439--------------------------------------------------------------------------------
Q16VL3_AEDAE/637-791--------------------------------------------------------------------------------
Q17FP9_AEDAE/355-509--------------------------------------------------------------------------------
Q17N28_AEDAE/360-513--------------------------------------------------------------------------------
Q18968_CAEEL/295-448--------------------------------------------------------------------------------
Q29GK5_DROPS/626-780--------------------------------------------------------------------------------
Q2HB50_CHAGB/263-415--------------------------------------------------------------------------------
A0A0D1C6G9_USTMA/410-564--------------------------------------------------------------------------------
B4Q8Q7_DROSI/652-804--------------------------------------------------------------------------------
F7ANF6_MACMU/1-147--------------------------------------------------------------------------------
G1MH71_AILME/663-814--------------------------------------------------------------------------------
H3CDQ1_TETNG/587-739--------------------------------------------------------------------------------
Q23E28_TETTS/401-549--------------------------------------------------------------------------------
Q7S7Y9_NEUCR/315-463--------------------------------------------------------------------------------

PF03176

MMPL8_MYCTU/74-402---------------A-ILPSDAPVLVSTRQMTAAFRE..AGLQSVA--VVVL.SDAKGLGA.ADERSYKELVDALRRDT
MMPL8_MYCTU/676-1049---------------G-LRGALATVIRAMGSLGMSSPGGVRS..KIN--LVNKGVNDLADGSRQLAEGVQLLVDQVKKMG
MMPL4_MYCTU/59-388---------------S-LSPKDAPSFEAMGRIGMVFKE..GDSDSFA--MVII.EGNQPLGD.AAHKYYDGLVAQLRADK
MMPL5_MYCTU/63-393---------------S-MSPDAAPSMISMKHIGKVFEE..GDSDSAA--MIVL.EGQRPLGD.AAHAFYDQMIGRLQADT
MMPL5_MYCTU/612-950---------------V-MTEDINNLLPLMQRLDTLMPQLTAMMPEMI--QTMKSMKAQMLSMHSTQEGLQDQMAAMQEDS
MMPLB_STRCO/48-383---------------N-LPPAASDSMKARDLVRAQLPG..QDATPAI--IVVRGKGTDAAKSATQSVAAITSALSGTSRP
MMPL4_MYCLE/57-385---------------S-LSPKDAPSYIAMQKMGQVFNE..GNSDSVI--MIVL.EGDKPLGD.DAHRFYDGLIRKLRAD.
MMPL7_MYCTU/74-391---------------A-LLPQDAKTAAATSRIAQAFPG..TGSNAIA--YLVV.EGGSTLEP.QDQPYYDAAVGALRADT
MMPLA_MYCTU/29-358---------------A-VLPADAPSSVAVRQMAEAFHE..SGSENIL--VVLL.TDEKGLGA.ADENVYHTLVDRLRNDA
MMPL1_MYCTU/52-381---------------A-LGPHDAPSLIAMKRIGKDFQQ..FDSDTTA--MVLL.EGQEKLGD.EAHRFYDVLVTKLSQDT
MMPL1_MYCTU/600-941---------------K-LTEDLANLTDDTERMDTTQRQLLAQLDPTI--ATMQTVKDLAQTLTSAFSGLVTQMEDMTRNA
MMPL9_MYCTU/58-387---------------A-VAPDDAQSMRAMRRAGKVFNE..FDSNSIA--MVVL.ESDQPLGE.KAHRYYDHLVDTLVLDQ
MMPL9_MYCTU/606-944---------------T-LTDQLRALTDDMNKMEALTPQFLALLPPMI--TTMKTMRTMMLTMRSTISGVQDQMADMQDHA
YDFJ_BACSU/44-362---------------D-MSIPDTPSEKAMDVIQKEFPH.GPDKGSIR--VIFGAGDGEKLTGKPAKKAIEDTFKEISKDD
YDGH_BACSU/39-360---------------A-QLPADAVS....ERANAILKQ.AGEDNNSI--SVVF.TLDNAIKK.ETENQLRIIIDKIKKID
MMPL6_MYCTU/28-366---------------Q-LGEQLASVTVTLDKLAAIQPQLVALLPDEI--ASQQINRELALANYATMSGIYAQTAALIENA
MMPL2_MYCTU/54-382---------------S-MSPSDAASIQAIKRVGQVFGE..FDSDNAV--TIVL.EGDQPLGG.DAHRFYSDLMRKLSADT
MMPL2_MYCTU/601-939---------------Q-LSEKLEYLVKDMDILITLLPQMRAQMPPMI--SAMTTMRDMMLIWHGTLGAFYKQQERNNKDP
MMPLA_MYCLE/55-391---------------V-ILPVDAPSSVAAKKISQAFHE..VDSENVL--IVLL.TDDKGLGP.ADETVYRTLVDRLRNDT
Q50086_MYCLR/31-369---------------Q-IDERLNSIVGDIKNMDLLMPQMLEQFPPMI--ESMESMRTIMLTMHSTMSGIFDQMNELSDNA
MMPLC_MYCTU/55-384---------------A-PLPPGAPSMVLQKEMSAAFQE.KIETSALL--LVLL.TNENGLGP.ADEAVYRKLIENLRADT
MMPLC_MYCTU/658-1001---------------T-LDGQLKQVVSTLKAV.....DGLPT..KLA--QMQQGANALADGSAALAAGVQELVDQVKKMG
MMPLA_STRCO/46-370---------------A-WLPGNAESTEVLE.LSEKFQP..ADTSPTV--IVYDRPSGITA...ADEAKARADATHFADGT
MMPLA_STRCO/397-682---------------D-GFKTKPESVVGEEILTRHFPA..GSGEPMV--VI............AKGASADQVHAALETVP
Q9RKC1_STRCO/44-379---------------S-FSIPGTEAQKAFDLLEQRFPGASADGATAR--VVFKAPAGETMTDAGNKATVEKTVDEL.ADG
Q9RL63_STRCO/44-395---------------S-DSMPGIESQHAFDLINERFPGAEAEGADAR--IVLVAPDGRQVTASEYRAAIDTLVAEV.ADG
MMPLD_STRCO/50-373---------------S-FLPRSAESTRVVD.AQQAFQQ..DETLPVI--VVWTADGDGDAAVTAHQQAATRSVAGLEGDP
A0A042QG29_MYCTX/43-376---------------P-FSPAGTATSRAVERSAAAFSQ..APGDNIG--YLVL.ERNGVLND.QDRAYYDALVVALRRDS
A0A042QG29_MYCTX/595-943---------------E-SCAKLADAAGQLARGIADVASATSGVSGLP--NALDGIGGQLAQVRESAAGVQELLNNV..GA
Q9XCF5_MYCAV/55-384---------------S-LSPIGAPSFKAMERLGEDFKE..TNTGALA--MILL.EGQQQLGD.DAHTYYDRLIRLLENDH
Q9XCF5_MYCAV/604-943---------------E-INDKLGDLVKNLDQLDALLPQLVMQIPPMI--ETMSSMRTMMLTMHSTMSGVMGQMDSSAKDP
Q9XCF6_MYCAV/51-382---------------P-LAPQDAPAVQAMQRMGRDFKE..SDSDSLR--HACCSEGHHQLGRLTAHAYYDKLVRELRNDT
Q9XCF6_MYCAV/601-939---------------T-LSDKMIDLVRDLDHMDRLMPLLLEQYPEMI--AMSEDMRNMLLTNHSTMSGIIGQMDSNSKDA
Q9Z577_STRCO/40-368---------------D-YGIPGTGSDRASRLLESRFPDLGGDSDT..--.IVWHTTSGTVRAADVEQAMTRTLDRI.ADL

PF00873

CZCA_RALME/5-1037IISFAIQQRWLVLLAV-FGMAGLGIFSYNRLPIDAVPD--ITNVQVQ--VNTSAPGYSPLETEQRATYPIEVVMAGLPGL
MEXB_PSEAE/1-1028MSKFFIDRPIFAWVIA-LVIMLAGGLSILSLPVNQYPA--IAPPAIA--VQVSYPGASAETVQDTVVQVIEQQMNGIDNL
MDTB_ECOLI/12-1023PSRLFIMRPVATTLLM-VAILLAGIIGYRALPVSALPE--VDYPTIQ--VVTLYPGASPDVMTSAVTAPLERQFGQMSGL
ACRF_ECOLI/1-1029MANFFIRRPIFAWVLA-IILMMAGALAILQLPVAQYPT--IAPPAVS--VSANYPGADAQTVQDTVTQVIEQNMNGIDNL
P74461_SYNY3/10-1047LSGLAIRRHIATLMLT-LAIIVLGVFAVFSLPVDLLPS--ITYPRIG--VRLDAPGVSPEVAVDEITRPLEAALSATEGV
O25622_HELPY/6-1014IIEFSLRQRVIVIVGA-ILILFFGTYSFINTPVDAFPD--ISPTQVK--IILKLPGSSPEEMENNIVRPLELELLGLKGQ
MDTF_ECOLI/1-1028MANYFIDRPVFAWVLA-IIMMLAGGLAIMNLPVAQYPQ--IAPPTIT--VSATYPGADAQTVEDSVTQVIEQNMNGLDGL
Q55935_SYNY3/9-1024ILKTSIAQRWFIVIAA-IGITLWGIISVGQMPLDVFPE--FAPPQVD--IHTEAPGLAPEEVETQITVPIESAVNGLPGV
ACRB_ECOLI/1-1030MPNFFIDRPIFAWVIA-IIIMLAGGLAILKLPVAQYPT--IAPPAVT--ISASYPGADAKTVQDTVTQVIEQNMNGIDNL
MDTC_ECOLI/3-1009FFALFIYRPVATILLS-VAITLCGILGFRMLPVAPLPQ--VDFPVII--VSASLPGASPETMASSVATPLERSLGRIAGV
ACRD_ECOLI/1-1027MANFFIDRPIFAWVLA-ILLCLTGTLAIFSLPVEQYPD--LAPPNVR--VTANYPGASAQTLENTVTQVIEQNMTGLDNL
P73998_SYNY3/2-1028FVDFFIKRPVFSSVCA-IIILLVGTISIFSLPIAQFPE--VAPTTIQ--VSSNYSGANAEVVERAVTDILERQINGVQGM
O25328_HELPY/1-1011MYKTAINRPITTLMFA-LAIVFFGTMGFKKLSVALFPK--IDLPTVV--VTTTYPGASAEIIESKVTDKIEEAVMGIDGI
Q5ZWS7_LEGPH/6-1036IIRFSLKHRWFVLLFT-FIIAVLGVYNFQRLPIDAVPD--ITNVQVQ--INTQASGYSPFEVEQRITFPIELAMSGLPNL
Q9I0Y8_PSEAE/3-1040FSQFFIQRPIFAAVLS-LLILIGGAISLFQLPISEYPE--VVPPTVV--VRANFPGANPKVIGETVASPLEQAITGVENM

PF02355

SECF_METTH/102-285-------------------------------------------------------------VSEA.LRGTAT....INSY
SECF_BORBU/108-297-------------------------------------------------------------TILDKLKETFDANIEVLDS
SECDF_BACSU/540-729-------------------------------------------------------------KVKTYFKDKYG...SDPNV
SECF_STRCO/109-305-------------------------------------------------------------IKEDLSKNLDV.SAEKINA
SECF_HAEIN/120-308-------------------------------------------------------------HVKSMLQNVDK.DIQIRSI
SECF_ECOLI/114-302-------------------------------------------------------------VLKVINESTNQ.NAAVKRI
SECF_SYNY3/108-301-------------------------------------------------------------VQKALNEGIGKFDPETIQI
SECF_RICPR/110-299-------------------------------------------------------------IIKTSLRNNFPYNFEYRKV
SECF_HELPY/106-293-------------------------------------------------------------IVANILKPSG..DFEIRKF
SECF_RHOCB/123-311-------------------------------------------------------------KVETALTAVDP.ALKITSF
SECF_METJA/88-276-------------------------------------------------------------QKIKEFFHVDSLDKLNYSE
SECF_TREPA/222-411-------------------------------------------------------------VYAALVRAYGADHVVRLAM
Q9ZBS8_STRCO/569-757-------------------------------------------------------------TVTKAVAELGG.ETEKVRD
SECF_RHOS4/117-305-------------------------------------------------------------QVEEALKTVDP.SITFPSV
O84454_CHLTR/1200-1393-------------------------------------------------------------DSGSSTTSMVF.DASRGSW
SECF_MYCLE/183-379-------------------------------------------------------------AFGPKGADAKP.SKQAISD
SECF_AQUAE/92-279-------------------------------------------------------------KLEDVLKKFG..KYELIRK

PF02460

O16307_CAEEL/1-766MDNLLRRDYLDGVD...SLAEYLQYNFTVPCS...GVRGENKLECSF..SDLCSGQCND.........NQKYLNKLRSNN
P91129_CAEEL/47-858NPLSDAVYLFTPLGAQ.SKMERMSIHEKWPLTDNNYIPGRAVTQSRE..IQVTALARND.....SNILDPKFANAVYQLD
O44978_CAEEL/31-791VLSSGLVHIRLEPDIRKAFSPDDSDAGYETRVWLEYYGLDIYPERAF..CIFTAKRENS......SILQEGALADIYTVD
Q18129_CAEEL/47-926QTTNDPQYVFSPANAP.WRYERAVLTEHWPLDEEKFWPGKSYDLHGY..VDVIASGRIHPDYGRPNILNIRYLDEVARIN
O61894_CAEEL/44-830IFSFGILNMRTEDDLR.FLYSPEHSLSREEYQVHKDFSGDSKNNSFV..SITIQTSSED.....KNLLKKDLAQKLIQLN
Q21883_CAEEL/44-838FCSSKICFTKQEDDIKTGYTPVGARSLDEIEVFSDFFASTGDPIAVF..LFITAKDNSS.......MADYNTMKEVVDIM
O16530_CAEEL/48-891VLSLKIPFTRMQNDIS.DFTPFGARSRVELEKYRKFFNNHGEPKAIY..AFITSKVGDN.......MLGISQLNDTVHVL
Q19945_CAEEL/49-901LRVDDPSYVFTPSDAR.WRREISVFNENWPLDENKFLPGKSFEAKRFVNILIRAKDGGS.......IMRDNVLHEIEILN
Q09938_CAEEL/52-945LTLLDARKLYTPVSAP.SWKEEQVFSELWPVKSYEFLPERTFQWNRY..LYLVVHGRPYENGTYPNILEGSYLNDIAKIE

PF12349

A1CTG5_ASPCL/632-787--------------------------------------------------------------------------------
A1Z6J2_DROME/390-543--------------------------------------------------------------------------------
PTC2_MOUSE/418-570--------------------------------------------------------------------------------
A4S8G2_OSTLU/258-409--------------------------------------------------------------------------------
A5E1Z8_LODEL/460-615--------------------------------------------------------------------------------
A7RI14_NEMVE/240-393--------------------------------------------------------------------------------
A7RNK5_NEMVE/879-1035--------------------------------------------------------------------------------
A7S0G1_NEMVE/641-795--------------------------------------------------------------------------------
NPC1_HUMAN/649-803--------------------------------------------------------------------------------
SCAP_SCHPO/257-410--------------------------------------------------------------------------------
P91346_CAEEL/298-449--------------------------------------------------------------------------------
PTR9_CAEEL/288-439--------------------------------------------------------------------------------
Q16VL3_AEDAE/637-791--------------------------------------------------------------------------------
Q17FP9_AEDAE/355-509--------------------------------------------------------------------------------
Q17N28_AEDAE/360-513--------------------------------------------------------------------------------
Q18968_CAEEL/295-448--------------------------------------------------------------------------------
Q29GK5_DROPS/626-780--------------------------------------------------------------------------------
Q2HB50_CHAGB/263-415--------------------------------------------------------------------------------
A0A0D1C6G9_USTMA/410-564--------------------------------------------------------------------------------
B4Q8Q7_DROSI/652-804--------------------------------------------------------------------------------
F7ANF6_MACMU/1-147--------------------------------------------------------------------------------
G1MH71_AILME/663-814--------------------------------------------------------------------------------
H3CDQ1_TETNG/587-739--------------------------------------------------------------------------------
Q23E28_TETTS/401-549--------------------------------------------------------------------------------
Q7S7Y9_NEUCR/315-463--------------------------------------------------------------------------------

PF03176

MMPL8_MYCTU/74-402RDVVMLQDF......................VT.......................TPP....LRELMTSK---------
MMPL8_MYCTU/676-1049FGLGEASAFLLAMKDTATTPAMAGFYIPPELLSYATGESVKAETMPSEYRDLLGGLNVDQLKKVAAAFISP---------
MMPL4_MYCTU/59-388KHVQSVQDL......................WG.......................DPL....TAAGVQSN---------
MMPL5_MYCTU/63-393THVQSLQDF......................WG.......................DPL....TATGAQSS---------
MMPL5_MYCTU/612-950AAMGEAFD.........ASRNDDSFYLPPEVFD.......................NPD.FQRGLEQFLSP---------
MMPLB_STRCO/48-383DHVVSVVST......................VT.......................APD....AAAELVSQ---------
MMPL4_MYCLE/57-385KHVQSVQDF......................WG.......................DPL....TAPGAQSN---------
MMPL7_MYCTU/74-391RHVGSVLDW......................WS.......................DPV....TAPLGTSP---------
MMPLA_MYCTU/29-358KDVVMLQDF......................LT.......................TPP....LREVLGSK---------
MMPL1_MYCTU/52-381THVQHIENF......................WG.......................DPL....TAAGSQSA---------
MMPL1_MYCTU/600-941TVMGRTFD.........AANNDDSFYLPPEAFQ.......................NPD.FQRGLKLFLSP---------
MMPL9_MYCTU/58-387SHIQHIQDF......................WR.......................DPL....TAAGAVSA---------
MMPL9_MYCTU/606-944TAMGQAFD.........TAKSGDSFYLPPEAFD.......................NAE.FQQGMKLFLSP---------
YDFJ_BACSU/44-362S.VDSIASP......................................................FVTGTIAK---------
YDGH_BACSU/39-360GVEEVTSPL......................SA.......................EKE....VKDQLMSK---------
MMPL6_MYCTU/28-366AAMGQAFD.........AAKNDDSFYLPPEAFD.......................NPD.FQRGLKLFLSA---------
MMPL2_MYCTU/54-382RHVAHIQDF......................WG.......................DPL....TAAGSQSA---------
MMPL2_MYCTU/601-939GAMGRVFD.........AAQIDDSFYLPQSAFE.......................NPD.FKRGLKMFLSP---------
MMPLA_MYCLE/55-391KDVVVLQDF......................LS.......................TPP....LHELLVSK---------
Q50086_MYCLR/31-369NTMGKAFD.........TAKNDDSFYLPPEVFK.......................NTD.FKRAMKSFLSS---------
MMPLC_MYCTU/55-384QDKISVQDF......................LA.......................VPE....MKELLASK---------
MMPLC_MYCTU/658-1001SGLNEAADFLLGIKRDADKPSMAGFNIPPQIFS.......................RDE.FKKGAQIFLSA---------
MMPLA_STRCO/46-370GVVGEPYGP..........................................................VRSD---------
MMPLA_STRCO/397-682GVIEVAPPQ............................................................VK---------
Q9RKC1_STRCO/44-379SEVASVADP......................................................YTGNAVSE---------
Q9RL63_STRCO/44-395PQVAAVSDP......................................................LDAATVSQ---------
MMPLD_STRCO/50-373GIVGPASPA..........................................................LPSD---------
A0A042QG29_MYCTX/43-376RHVIEVVDW......................WG.......................TPA....IAEVARSD---------
A0A042QG29_MYCTX/595-943APLRELPDYLRELAAVSQSAPGVDLYAARRILT.......................DPN.MRAVLDYFVSP---------
Q9XCF5_MYCAV/55-384KHVQHVQNF......................WG.......................DPL....TRGAAQSQ---------
Q9XCF5_MYCAV/604-943SAMGQAFD.........ASRNDDSFYLPPGIIN.......................GSDSFKRVEKVFMSP---------
Q9XCF6_MYCAV/51-382KHVEHVQDL......................WG.......................DRL....TQAGAQSP---------
Q9XCF6_MYCAV/601-939TAMGEAFD.........ASKNDDSFYLPPDIFE.......................NAD.FKKAMSQFLSP---------
Q9Z577_STRCO/40-368PGVAAVSNP...................................................YHDADSPLISE---------

PF00873

CZCA_RALME/5-1037EQTRSLS.RYGLSQVTVIFKDGTDVYFARQLVNQRIQEAKDNLPEGV..VPAMGPISTGLGEIYLWTVEAEEGARKADGT
MEXB_PSEAE/1-1028RYISSESNSDGSMTITVTFEQGTDPDIAQVQVQNKLQLATPLLPQEV.QRQGIRVTKAVKNFLMVVGVVST.......DG
MDTB_ECOLI/12-1023KQMSSQS.SGGASVITLQFQLTLPLDVAEQEVQAAINAATNLLPSDLPNPPVYSKVNPADPPIMTLAVTST.........
ACRF_ECOLI/1-1029MYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATPLLPQEV.QQQGISVEKSSSSYLMVAGFVSD.......NP
P74461_SYNY3/10-1047VQVYSQT.REGQISLDLFFEPGGNIDQALNDATATFNRARNQLPDDL.ETPRLFKFDPSQLPVYEFAVTSP.........
O25622_HELPY/6-1014KSLRSVS.KYSISDITIDFDDSVDIYLARNIVNERLSSVMKDLPVGV..EGGMAPIVTPLSDIFMFTIDGN.........
MDTF_ECOLI/1-1028MYMSSTSDAAGNASITLTFETGTSPDIAQVQVQNKLQLAMPSLPEAV.QQQGISVDKSSSNILMVAAFISD.......NG
Q55935_SYNY3/9-1024TTVRSSS.KVGLSMVSVVFDQDADVYKARQTVTERLQQVTNQLPEGS.HPPEISPLVSPLGTIVQYAFTIK......DGG
ACRB_ECOLI/1-1030MYMSSNSDSTGTVQITLTFESGTDADIAQVQVQNKLQLAMPLLPQEV.QQQGVSVEKSSSSFLMVVGVINT.......DG
MDTC_ECOLI/3-1009SEMTSSS.SLGSTRIILQFDFDRDINGAARDVQAAINAAQSLLPSGMPSRPTYRKANPSDAPIMILTLTSD.........
ACRD_ECOLI/1-1027MYMSSQSSGTGQASVTLSFKAGTDPDEAVQQVQNQLQSAMRKLPQAV.QNQGVTVRKTGDTNILTIAFVST.......DG
P73998_SYNY3/2-1028RYISSTSSNDGTSSITVTFDRSQNKDIAAVDVQNRVALAEPQLPEAV.RRTGIRVNKESNALLLGIGITSP.......DG
O25328_HELPY/1-1011KKVTSTS.SKNVSIVVIEFELEKPNEEALNDVVNKISSVRFD.DSNI.KKPSINKFDTDSQAIISLFVSSS.........
Q5ZWS7_LEGPH/6-1036DYTRSLS.RYGLSQVTVVFKDGTNIYFARQLINERLQEVKDKLPPEA..ETTLGPISTGLGEIFMYTVTNKSN..LPKSQ
Q9I0Y8_PSEAE/3-1040LYMSSQSTSDGKLTLTITFALGTDLDNAQVQVQNRVTRTEPKLPEEV.TRLGITVDKASPDLTMVVHLTSP.......DN

PF02355

SECF_METTH/102-285KAVGPVLSK-----------------------------------------------------------------------
SECF_BORBU/108-297YFIDSSFSS-----------------------------------------------------------------------
SECDF_BACSU/540-729STVSPTVGK-----------------------------------------------------------------------
SECF_STRCO/109-305DLVGPSWGD-----------------------------------------------------------------------
SECF_HAEIN/120-308EFVGPNVGE-----------------------------------------------------------------------
SECF_ECOLI/114-302EFVGPSVGA-----------------------------------------------------------------------
SECF_SYNY3/108-301DTVGPTVGK-----------------------------------------------------------------------
SECF_RICPR/110-299DFVGPQVGR-----------------------------------------------------------------------
SECF_HELPY/106-293DTVGPRVGS-----------------------------------------------------------------------
SECF_RHOCB/123-311ESVGPKVSG-----------------------------------------------------------------------
SECF_METJA/88-276KTIGATLSS-----------------------------------------------------------------------
SECF_TREPA/222-411DFVGSRFSH-----------------------------------------------------------------------
Q9ZBS8_STRCO/569-757ELIGPSLGE-----------------------------------------------------------------------
SECF_RHOS4/117-305ESVGPKVSG-----------------------------------------------------------------------
O84454_CHLTR/1200-1393FKVSGQLSN-----------------------------------------------------------------------
SECF_MYCLE/183-379AAVSETWGG-----------------------------------------------------------------------
SECF_AQUAE/92-279ETISGVVSE-----------------------------------------------------------------------

PF02460

O16307_CAEEL/1-766EKNLQ.........................VIPLFN......LIYRNASSRL.....HPN....................
P91129_CAEEL/47-858KYIQTRV.......................RVLHNG....HYYSYKNLCLQYKNGGCPSNKHV.................
O44978_CAEEL/31-791NRLSAAV.......................GYQDGD......G..RKNCDPLCDLNSPFHLLAN................
Q18129_CAEEL/47-926DYIIHNL.......................TVPVDINGKHYDIAYTDLCMRY.DWACYLNDHITMLMPKTRWGNFSGPFA
O61894_CAEEL/44-830KYVLEKM.......................EIQVDG...KIINFGKEVCSRMKQCELSNTIATIFLD...........TF
Q21883_CAEEL/44-838DYVGSN.........................LTHKG......ESFYTLCTDFCQINEPVRQYYNGL.............A
O16530_CAEEL/48-891DTISRDF.......................YLKTSQ....GPKNFEEYCSGFCLLNEPVKHFYSG...............
Q19945_CAEEL/49-901QWIMNNI.......................SIPTDDL..KFNLTYQDLCLSY.DWVCGANEHIQM..............L
Q09938_CAEEL/52-945EELVTNVSFPREAALEDNPALMRKRHLNETEIEENR...NITITFKDVCMNW.YGDCYREKNVI................

PF12349

A1CTG5_ASPCL/632-787--------------------------------------------------------------------------------
A1Z6J2_DROME/390-543--------------------------------------------------------------------------------
PTC2_MOUSE/418-570--------------------------------------------------------------------------------
A4S8G2_OSTLU/258-409--------------------------------------------------------------------------------
A5E1Z8_LODEL/460-615--------------------------------------------------------------------------------
A7RI14_NEMVE/240-393--------------------------------------------------------------------------------
A7RNK5_NEMVE/879-1035--------------------------------------------------------------------------------
A7S0G1_NEMVE/641-795--------------------------------------------------------------------------------
NPC1_HUMAN/649-803--------------------------------------------------------------------------------
SCAP_SCHPO/257-410--------------------------------------------------------------------------------
P91346_CAEEL/298-449--------------------------------------------------------------------------------
PTR9_CAEEL/288-439--------------------------------------------------------------------------------
Q16VL3_AEDAE/637-791--------------------------------------------------------------------------------
Q17FP9_AEDAE/355-509--------------------------------------------------------------------------------
Q17N28_AEDAE/360-513--------------------------------------------------------------------------------
Q18968_CAEEL/295-448--------------------------------------------------------------------------------
Q29GK5_DROPS/626-780--------------------------------------------------------------------------------
Q2HB50_CHAGB/263-415--------------------------------------------------------------------------------
A0A0D1C6G9_USTMA/410-564--------------------------------------------------------------------------------
B4Q8Q7_DROSI/652-804--------------------------------------------------------------------------------
F7ANF6_MACMU/1-147--------------------------------------------------------------------------------
G1MH71_AILME/663-814--------------------------------------------------------------------------------
H3CDQ1_TETNG/587-739--------------------------------------------------------------------------------
Q23E28_TETTS/401-549--------------------------------------------------------------------------------
Q7S7Y9_NEUCR/315-463--------------------------------------------------------------------------------

PF03176

MMPL8_MYCTU/74-402-------------------------------------------------------------------------------D
MMPL8_MYCTU/676-1049-------------------------------------------------------------------------------D
MMPL4_MYCTU/59-388-------------------------------------------------------------------------------D
MMPL5_MYCTU/63-393-------------------------------------------------------------------------------D
MMPL5_MYCTU/612-950-------------------------------------------------------------------------------D
MMPLB_STRCO/48-383-------------------------------------------------------------------------------D
MMPL4_MYCLE/57-385-------------------------------------------------------------------------------D
MMPL7_MYCTU/74-391-------------------------------------------------------------------------------D
MMPLA_MYCTU/29-358-------------------------------------------------------------------------------D
MMPL1_MYCTU/52-381-------------------------------------------------------------------------------D
MMPL1_MYCTU/600-941-------------------------------------------------------------------------------D
MMPL9_MYCTU/58-387-------------------------------------------------------------------------------D
MMPL9_MYCTU/606-944-------------------------------------------------------------------------------N
YDFJ_BACSU/44-362-------------------------------------------------------------------------------D
YDGH_BACSU/39-360-------------------------------------------------------------------------------D
MMPL6_MYCTU/28-366-------------------------------------------------------------------------------D
MMPL2_MYCTU/54-382-------------------------------------------------------------------------------D
MMPL2_MYCTU/601-939-------------------------------------------------------------------------------D
MMPLA_MYCLE/55-391-------------------------------------------------------------------------------D
Q50086_MYCLR/31-369-------------------------------------------------------------------------------D
MMPLC_MYCTU/55-384-------------------------------------------------------------------------------D
MMPLC_MYCTU/658-1001-------------------------------------------------------------------------------D
MMPLA_STRCO/46-370-------------------------------------------------------------------------------D
MMPLA_STRCO/397-682-------------------------------------------------------------------------------D
Q9RKC1_STRCO/44-379-------------------------------------------------------------------------------D
Q9RL63_STRCO/44-395-------------------------------------------------------------------------------D
MMPLD_STRCO/50-373-------------------------------------------------------------------------------D
A0A042QG29_MYCTX/43-376-------------------------------------------------------------------------------D
A0A042QG29_MYCTX/595-943-------------------------------------------------------------------------------N
Q9XCF5_MYCAV/55-384-------------------------------------------------------------------------------D
Q9XCF5_MYCAV/604-943-------------------------------------------------------------------------------D
Q9XCF6_MYCAV/51-382-------------------------------------------------------------------------------D
Q9XCF6_MYCAV/601-939-------------------------------------------------------------------------------D
Q9Z577_STRCO/40-368-------------------------------------------------------------------------------N

PF00873

CZCA_RALME/5-1037AYTPTDLREIQDWVVRPQLRNVPGVTEINTIGGFNKQYLVAPSLERLASYGLTLTDVVNALNKNNDNVGAGYI......E
MEXB_PSEAE/1-1028SMTKEDLSNYIVSNIQDPLSRTKGVGDFQVFG.SQYSMRIWLDPAKLNSYQLTPGDVSSAIQAQNVQISSGQLGGLPAVK
MDTB_ECOLI/12-1023AMPMTQVEDMVETRVAQKISQISGVGLVTLSGGQRPAVRVKLNAQAIAALGLTSETVRTAITGANVNSAKGSL......D
ACRF_ECOLI/1-1029GTTQDDISDYVASNVKDTLSRLNGVGDVQLFG.AQYAMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALP
P74461_SYNY3/10-1047ELSGPSLRVFAEEELARELGVVPGVASVNVSGAAQEEVRINVDLQRLQRSGVSLTQVLDALQSRNVDISGGRI......V
O25622_HELPY/6-1014.ITEIEKRQLLDFVIRPQLRMISGVADVNSIGGFSRAFVIVPDFNDMARLGVSISDLESAVRVNLRNSGAGRV......D
MDTF_ECOLI/1-1028SLNQYDIADYVASNIKDPLSRTAGVGSVQLFG.SEYAMRIWLDPQKLNKYNLVPSDVISQIKVQNNQISGGQLGGMPQAA
Q55935_SYNY3/9-1024SSNLMDLRRLLETTVGNQLLSVPGVSQVTLYGGDERQEQVLVDPAKLRALKVSLNEVTQASAEANSNAPGGFL......I
ACRB_ECOLI/1-1030TMTQEDISDYVAANMKDAISRTSGVGDVQLFG.SQYAMRIWMNPNELNKFQLTPVDVITAIKAQNAQVAAGQLGGTPPVK
MDTC_ECOLI/3-1009TYSQGELYDFASTQLAPTISQIDGVGDVDVGGSSLPAVRVGLNPQALFNQGVSLDDVRTAVSNANVRKPQGAL......E
ACRD_ECOLI/1-1027SMDKQDIADYVASNIQDPLSRVNGVGDIDAYG.SQYSMRIWLDPAKLNSFQMTAKDVTDAIESQNAQIAVGQLGGTPSVD
P73998_SYNY3/2-1028EYDNVFLSNYADRYLVDPIRRLEGVGDVRIFGERLYAMRLWVDPMKLAAQQLTMADLSRALQEQNLQVGAGQIGAEPAPP
O25328_HELPY/1-1011SVPATTLNDYAKNTIKPMLQKINGVGGVQLNGFRERQIRIYANPTLMNKYNLTYADLFSTLKAENVEIDGGRI......V
Q5ZWS7_LEGPH/6-1036RYNPMELRTIQDWIIKPQLRNVEGVAEVNTIGGYEKQFHITPDPTKLVRYGLSLNNVVEALERNNANVGAGYI......E
Q9I0Y8_PSEAE/3-1040RYDMLYLSNYAVLNVKDELARLDGVGDVQLFGLGDYSLRVWLDPNKVASRNLTATDVVNAIREQNRQVAAGTLGAPPAPS

PF02355

SECF_METTH/102-285--------------------------------------------------------------------------------
SECF_BORBU/108-297--------------------------------------------------------------------------------
SECDF_BACSU/540-729--------------------------------------------------------------------------------
SECF_STRCO/109-305--------------------------------------------------------------------------------
SECF_HAEIN/120-308--------------------------------------------------------------------------------
SECF_ECOLI/114-302--------------------------------------------------------------------------------
SECF_SYNY3/108-301--------------------------------------------------------------------------------
SECF_RICPR/110-299--------------------------------------------------------------------------------
SECF_HELPY/106-293--------------------------------------------------------------------------------
SECF_RHOCB/123-311--------------------------------------------------------------------------------
SECF_METJA/88-276--------------------------------------------------------------------------------
SECF_TREPA/222-411--------------------------------------------------------------------------------
Q9ZBS8_STRCO/569-757--------------------------------------------------------------------------------
SECF_RHOS4/117-305--------------------------------------------------------------------------------
O84454_CHLTR/1200-1393--------------------------------------------------------------------------------
SECF_MYCLE/183-379--------------------------------------------------------------------------------
SECF_AQUAE/92-279--------------------------------------------------------------------------------

PF02460

O16307_CAEEL/1-766.......------------------------------------------------------------------------.
P91129_CAEEL/47-858HILSDLH------------------------------------------------------------------------N
O44978_CAEEL/31-791.LTRRNN------------------------------------------------------------------------G
Q18129_CAEEL/47-926ELASDII------------------------------------------------------------------------N
O61894_CAEEL/44-830WSEKLRK------------------------------------------------------------------------D
Q21883_CAEEL/44-838MKQQNLS------------------------------------------------------------------------E
O16530_CAEEL/48-891MLISGQH------------------------------------------------------------------------G
Q19945_CAEEL/49-901.LRRNDV------------------------------------------------------------------------N
Q09938_CAEEL/52-945ELLKRRH------------------------------------------------------------------------E

PF12349

A1CTG5_ASPCL/632-787--------------------------------------------------------------------------------
A1Z6J2_DROME/390-543--------------------------------------------------------------------------------
PTC2_MOUSE/418-570--------------------------------------------------------------------------------
A4S8G2_OSTLU/258-409--------------------------------------------------------------------------------
A5E1Z8_LODEL/460-615--------------------------------------------------------------------------------
A7RI14_NEMVE/240-393--------------------------------------------------------------------------------
A7RNK5_NEMVE/879-1035--------------------------------------------------------------------------------
A7S0G1_NEMVE/641-795--------------------------------------------------------------------------------
NPC1_HUMAN/649-803--------------------------------------------------------------------------------
SCAP_SCHPO/257-410--------------------------------------------------------------------------------
P91346_CAEEL/298-449--------------------------------------------------------------------------------
PTR9_CAEEL/288-439--------------------------------------------------------------------------------
Q16VL3_AEDAE/637-791--------------------------------------------------------------------------------
Q17FP9_AEDAE/355-509--------------------------------------------------------------------------------
Q17N28_AEDAE/360-513--------------------------------------------------------------------------------
Q18968_CAEEL/295-448--------------------------------------------------------------------------------
Q29GK5_DROPS/626-780--------------------------------------------------------------------------------
Q2HB50_CHAGB/263-415--------------------------------------------------------------------------------
A0A0D1C6G9_USTMA/410-564--------------------------------------------------------------------------------
B4Q8Q7_DROSI/652-804--------------------------------------------------------------------------------
F7ANF6_MACMU/1-147--------------------------------------------------------------------------------
G1MH71_AILME/663-814--------------------------------------------------------------------------------
H3CDQ1_TETNG/587-739--------------------------------------------------------------------------------
Q23E28_TETTS/401-549--------------------------------------------------------------------------------
Q7S7Y9_NEUCR/315-463--------------------------------------------------------------------------------

PF03176

MMPL8_MYCTU/74-402NQAWILPVGLPGDLGSTQSKQAYARV-------------------------------------ADIVEHQV...AGSTLT
MMPL8_MYCTU/676-1049GHSIRYLIQTDLNPFSTAAMDQIDAI-------------------------------------TAAARGAQPNTALADAK
MMPL4_MYCTU/59-388GKAAYVQLSLAGNQGTPLANESVEAV-------------------------------------RSIVESTP...APPGIK
MMPL5_MYCTU/63-393GKAAYVQVKLAGNQGESLANESVEAV-------------------------------------KTIVERLA...PPPGVK
MMPL5_MYCTU/612-950GHAVRFIISHEGDPMSQAGIARIAKI-------------------------------------KTAAKEAIKGTPLEGSA
MMPLB_STRCO/48-383RGAQLVIVPMEGSPSDESFQNAVDEV-------------------------------------RALASDRA.....GPAD
MMPL4_MYCLE/57-385GKAAYVQLSLAGNQGELLAQESIDAV-------------------------------------RKIVVQTP...APPGIT
MMPL7_MYCTU/74-391GRSATAMVWLRGEAGTTQAAESLDAV-------------------------------------RSVLRQLP...PSEGLR
MMPLA_MYCTU/29-358GKAWILPIGLAGDLGTPKSYHAYTDV-------------------------------------ERIVKRTV...AGTTLT
MMPL1_MYCTU/52-381GKAAYVQLNLTGDQGGSQANESVAAV-------------------------------------QRIVDSVP...PPPGIK
MMPL1_MYCTU/600-941GTCARFVITHRGDPASAEGISHIDPI-------------------------------------MQAADEAVKGTPLQAAS
MMPL9_MYCTU/58-387GKAAYVQLYLAGNMGEALANESVEAV-------------------------------------RKIVANST...PPEGIR
MMPL9_MYCTU/606-944GKAVRFVISHESDPASTEGIDRIEAI-------------------------------------RAATKDAIKATPLQGAK
YDFJ_BACSU/44-362GTVAYADIQYK.SSADDIKDYSIKHL-------------------------------------KDSLKMAD....DEGLQ
YDGH_BACSU/39-360KKTVLMPVTITG......SDKKAEKI-------------------------------------ADEIYQIV....PDDLT
MMPL6_MYCTU/28-366GKAARMIISHEGDPATPEGISHIDAI-------------------------------------KQAAHEAVKGTPMAGAG
MMPL2_MYCTU/54-382DRAAYVVVYLVGN.NETEAYDSVHAV-------------------------------------RHMVDTTP...PPHGVK
MMPL2_MYCTU/601-939GKAARFVIALEGDPATPEGISRVEPI-------------------------------------KREAREAIKGTPLQGAA
MMPLA_MYCLE/55-391GKAWILPIVLAGELGTSASYQAYAGV-------------------------------------AGIVKQTLESTAGSSLK
Q50086_MYCLR/31-369GHAARFIILHRGDPASVAGIASINAI-------------------------------------RTAAEEALKGTPLEDTK
MMPLC_MYCTU/55-384NKAWNLPITFAGDAASPETQAAFKRV-------------------------------------AAIVKQTV...AGTSLT
MMPLC_MYCTU/658-1001GHAARYFVQSALNPATTEAMDQVNDI-------------------------------------LRVADSARPNTELEDAT
MMPLA_STRCO/46-370GKALRTVVNVHLGKDGWEGLNAAAKD-------------------------------------MRAIARPS...APDGLG
MMPLA_STRCO/397-682GLA.YVEATLGAGADSPAAMRSVTAA-------------------------------------RETLARLD......GAQ
Q9RKC1_STRCO/44-379GTIAYASVKYD.VSGMELEESTKDAL-------------------------------------EDAAQQAR....DAGLT
Q9RL63_STRCO/44-395GSTAYATVTYE.VTEDNVTDAGRADL-------------------------------------TAAVERAR....TSGLT
MMPLD_STRCO/50-373GRALQAVVQVEPDLGERLP.DVLADI-------------------------------------GDAAGQVP......GTR
A0A042QG29_MYCTX/43-376HHAVTAALRFGGMVGTSQAGESITAA-------------------------------------RSIVTQLH...PPDGLH
A0A042QG29_MYCTX/595-943GHATRLLVYGDGSEWGDDGAQRARAI-------------------------------------VTAVAEETDEGTLRPTA
Q9XCF5_MYCAV/55-384GKAAYVQVNLNGNAGAAAGDESVAAI-------------------------------------RKLVQEAS...PPPGLK
Q9XCF5_MYCAV/604-943GKDVRLLISQRGDPATPEGLSRVEQI-------------------------------------KTAAEEALKGTPLENSR
Q9XCF6_MYCAV/51-382GKAVYVQLNLAGNQGTTLGQESVAAV-------------------------------------RDAIARIP...PPAGLK
Q9XCF6_MYCAV/601-939GKAARFIISHRGDPATSEALNRIDKI-------------------------------------RSAAEEALKNTPLENAK
Q9Z577_STRCO/40-368ADTAYATVTFE.DASQDLDPGQARAV-------------------------------------VDTAEAAE....TGGLR

PF00873

CZCA_RALME/5-1037RRGEQYLVRAPGQVASEDDIRNIIVG......TAQGQPIRIRDIGDVEIGKELRTGAATENG.KEVVLGTVFMLIGENSR
MEXB_PSEAE/1-1028GQQLNATIIGKTRLQTAEQFENILLK.....VNPDGSQVRLKDVADVGLGGQDYSINAQFNG.SPASGIAIKLATGANAL
MDTB_ECOLI/12-1023GPSRAVTLSANDQMQSAEEYRQLIIA......YQNGAPIRLGDVATVEQGAENSWLGAWANK.EQAIVMNVQRQPGANII
ACRF_ECOLI/1-1029GQQLNASIIAQTRFKNPEEFGKVTLR.....VNSDGSVVRLKDVARVELGGENYNVIARING.KPAAGLGIKLATGANAL
P74461_SYNY3/10-1047GTESEPLTRTVGRFASAQEIEDLVVGTVSGLEDQSAQKVYLRDVATVIDGTEEERIFVTLNG.NPAVKVSVQKQPEANTI
O25622_HELPY/6-1014RDGETFLVKIQTASLSLEDIGKITV.......STNLGHLHIKDFAKVISQSRTRLGFVTKDGVGETTEGLVLSLKDANTK
MDTF_ECOLI/1-1028DQQLNASIIVQTRLQTPEEFGKILLK.....VQQDGSQVLLRDVARVELGAEDYSTVARYNG.KPAAGIAIKLAAGANAL
Q55935_SYNY3/9-1024GGGQELLVRGLGQMQSIEDLRRSVVK......VVDGKPILLEDVAEVKTGSALKRGDGSFNG.QPAIVMMVNKQPDVDTP
ACRB_ECOLI/1-1030GQQLNASIIAQTRLTSTEEFGKILLK.....VNQDGSRVLLRDVAKIELGGENYDIIAEFNG.QPASGLGIKLATGANAL
MDTC_ECOLI/3-1009DGTHRWQIQTNDELKTAAEYQPLIIH......YNNGGAVRLGDVATVTDSVQDVRNAGMTNA.KPAILLMIRKLPEANII
ACRD_ECOLI/1-1027KQALNATINAQSLLQTPEQFRDITLR.....VNQDGSEVRLGDVATVEMGAEKYDYLSRFNG.KPASGLGVKLASGANEM
P73998_SYNY3/2-1028GQEYQLDLLASSQLVEVKDFEDLIVK.....SGASGSVVRFKDIGRVELGAQNYNSFLRFRG.DEAVGLGIYQLLDSNAL
O25328_HELPY/1-1011NSQREFSILINANSYSVADVEKIQV..........GNHVRLGDIAKIEIGLEEDNTFASFKD.KPGVILEIQKIAGANEI
Q5ZWS7_LEGPH/6-1036RNGEQNLIRVPGQVKNIADIENIVVA......NFEGTPVRIRDVAEVALGKELRTGAATENG.DEVVLGTVFMLMGENSR
Q9I0Y8_PSEAE/3-1040DTSFQLSINTQGRLVTEEEFENIIIR.....AGANGEITRLRDIARVELGSNQYALRSLLNN.KPAVAIPIFQRPGSNAI

PF02355

SECF_METTH/102-285--------------------------------------------------------------------------------
SECF_BORBU/108-297--------------------------------------------------------------------------------
SECDF_BACSU/540-729--------------------------------------------------------------------------------
SECF_STRCO/109-305--------------------------------------------------------------------------------
SECF_HAEIN/120-308--------------------------------------------------------------------------------
SECF_ECOLI/114-302--------------------------------------------------------------------------------
SECF_SYNY3/108-301--------------------------------------------------------------------------------
SECF_RICPR/110-299--------------------------------------------------------------------------------
SECF_HELPY/106-293--------------------------------------------------------------------------------
SECF_RHOCB/123-311--------------------------------------------------------------------------------
SECF_METJA/88-276--------------------------------------------------------------------------------
SECF_TREPA/222-411--------------------------------------------------------------------------------
Q9ZBS8_STRCO/569-757--------------------------------------------------------------------------------
SECF_RHOS4/117-305--------------------------------------------------------------------------------
O84454_CHLTR/1200-1393--------------------------------------------------------------------------------
SECF_MYCLE/183-379--------------------------------------------------------------------------------
SECF_AQUAE/92-279--------------------------------------------------------------------------------

PF02460

O16307_CAEEL/1-766.....FRLTYPTMHLYNDEYYVGEHFAGVKIDP......................NTNVISRVKVVVLYFRTDRQTTEVS
P91129_CAEEL/47-858...HGFNITYPYFRFGSEGGYIGSSLGGVTVMKG...................ENETDILASAKAWFMIYHLKFHPEEMS
O44978_CAEEL/31-791...TTSVFTYPDMPYSGLDIFLGLHLSNADFEP.......................PTERISSKSLVLWYFSRSDTPEGK
Q18129_CAEEL/47-926...TQVNITYPIGWRGTEPIYFGALVGAPNLVD......................EEGHFDYASAIRLTYNTR..EGKVD
O61894_CAEEL/44-830...PRIKIEYPTMKFFDNKFFLPTHFYGVQPGG......................PLGIESIDMVHFVYQIPAYNEHTSE
Q21883_CAEEL/44-838V.GSRFQLTFPMMQVLGKELDLSPNFFGVKTDE.......................DGNVEYVKIIMLQIRANIPNDWKK
O16530_CAEEL/48-891TDFSHLDLGYPITTVLGTKLYMDPNFFGVKVTTSNNKVESIADGNTKLFGDHTKQEPNNIREVSLVVLQFRSELGDEVTP
Q19945_CAEEL/49-901...QILDLHFPRGGTKDTPVYLGGIFGDVQFFQ.......................NGTLSDAKLTQLFYFLKQDQKMVE
Q09938_CAEEL/52-945LNKRGISVTFPQVNQEGTPIYIAFVIGGVDTYP.......................NDTIKYARAMRLWYFLKFDDEEQE

PF12349

A1CTG5_ASPCL/632-787----------------------------------------------------------F---------------------
A1Z6J2_DROME/390-543----------------------------------------------------------V---------------------
PTC2_MOUSE/418-570----------------------------------------------------------C---------------------
A4S8G2_OSTLU/258-409----------------------------------------------------------C---------------------
A5E1Z8_LODEL/460-615----------------------------------------------------------L---------------------
A7RI14_NEMVE/240-393----------------------------------------------------------M---------------------
A7RNK5_NEMVE/879-1035----------------------------------------------------------R---------------------
A7S0G1_NEMVE/641-795----------------------------------------------------------M---------------------
NPC1_HUMAN/649-803----------------------------------------------------------L---------------------
SCAP_SCHPO/257-410----------------------------------------------------------D---------------------
P91346_CAEEL/298-449----------------------------------------------------------W---------------------
PTR9_CAEEL/288-439----------------------------------------------------------I---------------------
Q16VL3_AEDAE/637-791----------------------------------------------------------F---------------------
Q17FP9_AEDAE/355-509----------------------------------------------------------L---------------------
Q17N28_AEDAE/360-513----------------------------------------------------------V---------------------
Q18968_CAEEL/295-448----------------------------------------------------------M---------------------
Q29GK5_DROPS/626-780----------------------------------------------------------L---------------------
Q2HB50_CHAGB/263-415----------------------------------------------------------A---------------------
A0A0D1C6G9_USTMA/410-564----------------------------------------------------------K---------------------
B4Q8Q7_DROSI/652-804----------------------------------------------------------.---------------------
F7ANF6_MACMU/1-147----------------------------------------------------------M---------------------
G1MH71_AILME/663-814----------------------------------------------------------.---------------------
H3CDQ1_TETNG/587-739----------------------------------------------------------.---------------------
Q23E28_TETTS/401-549----------------------------------------------------------.---------------------
Q7S7Y9_NEUCR/315-463----------------------------------------------------------.---------------------

PF03176

MMPL8_MYCTU/74-402ANLTGPAATVADLNLT---------------------GQRDRSRIEFAITILLLVILLI---------------------
MMPL8_MYCTU/676-1049VSVVGLPVVLKDTRDY---------------------SDHDLRLIIAMTVCIVLLILIV---------------------
MMPL4_MYCTU/59-388AYVTGPSALAADMHHS---------------------GDRSMARITMVTVAVIFIMLLL---------------------
MMPL5_MYCTU/63-393VYVTGSAALVADQQQA---------------------GDRSLQVIEAVTFTVIIVMLLL---------------------
MMPL5_MYCTU/612-950IYLGGTAAMFKDLSDG---------------------NTYDLMIAGISALCLIFIIMLI---------------------
MMPLB_STRCO/48-383VAVTGPAGIATDTVKV---------------------FSGGDKVLLLATVVLVLIILLA---------------------
MMPL4_MYCLE/57-385AWVTGASALIADMHHS---------------------GDKSMIRITATSVIVILVTLLL---------------------
MMPL7_MYCTU/74-391ASIVVPAITNDMPMQI---------------------TAWQSATIVTVAAVIAVLLLLR---------------------
MMPLA_MYCTU/29-358ANVTGPAATVADLTDA---------------------GARDRASIELAIAVMLLVILMV---------------------
MMPL1_MYCTU/52-381AYVTGPGPLGADRVVY---------------------GDRSLHTITGISIAVIAIMLFI---------------------
MMPL1_MYCTU/600-941IYLAGTSSTYKDIHEG---------------------TLYDVMIAVVASLCLIFIIMLG---------------------
MMPL9_MYCTU/58-387TYVTGPAALFADQIAA---------------------GDRSMKLITGLTFAVITVLLLL---------------------
MMPL9_MYCTU/606-944IYIGGTAATYQDIRDG---------------------TKYDILIVGIAAVCLVFIVMLM---------------------
YDFJ_BACSU/44-362TELSG......DVPGA---------------------EMEIGGVSEIVGIILAFVVLAI---------------------
YDGH_BACSU/39-360AYITGASLINQDFAHS---------------------SEEGLKKTEVITVCLIIGLLLI---------------------
MMPL6_MYCTU/28-366IYLAGTAATFKDIQDG---------------------ATYDLLIAGIAALSLILLIMMI---------------------
MMPL2_MYCTU/54-382AYVTGPAALNADQAEA---------------------GDKSIAKVTAITSMVIAAMLLV---------------------
MMPL2_MYCTU/601-939IYLGGTAATFKDIREG---------------------ARYDLLIAGVAAISLILIIMMI---------------------
MMPLA_MYCLE/55-391ANLTGPASTVADLTDA---------------------GARDRTSIELVIAVLLLTILMI---------------------
Q50086_MYCLR/31-369IYLAGTAAVFKDIDEG---------------------ANWDLVIAGISSLCLIFIIMLI---------------------
MMPLC_MYCTU/55-384VHLSGPIATVADLTEL---------------------GEKDVRIIEIGTAVSVLIILIL---------------------
MMPLC_MYCTU/658-1001IGLAGVPTALRDIRDY---------------------YNSDMKFIVIATIVIVFLILVI---------------------
MMPLA_STRCO/46-370VHVTGPTGYAADSAES---------------------FSSADFKLTLVTLLIVVTILVV---------------------
MMPLA_STRCO/397-682ARVGGSSAVVHDMREA---------------------SSRDRGLIIPVILAVVFCILAL---------------------
Q9RKC1_STRCO/44-379VEIGGDALQAVP....---------------------...ETGATEVIGIAVAAVVLVI---------------------
Q9RL63_STRCO/44-395VEAGGGAVAGEP....---------------------...PAGIGEFLGIGVAAVVLLI---------------------
MMPLD_STRCO/50-373AQLAGPAASQADLSDA---------------------FAGIDGLLLAVALITVLVILLL---------------------
A0A042QG29_MYCTX/43-376VFVTGPGATIVDEFAA---------------------IDRQTQLITATTIVVLLILLLI---------------------
A0A042QG29_MYCTX/595-943VELTGVGPATRDLQDL---------------------VGSDLTLLAVITLAVIFAIAAL---------------------
Q9XCF5_MYCAV/55-384VYVTGPAPIVADMNIA---------------------GQKTVMLVTLASLIVIFVTLLL---------------------
Q9XCF5_MYCAV/604-943IYLTGTAAITKDLAQG---------------------SKFDLLIAGVSALCLIFIIMLI---------------------
Q9XCF6_MYCAV/51-382AYVTGPAALFSDMQLA---------------------GDRSILKMTLIGALIIFIVLLF---------------------
Q9XCF6_MYCAV/601-939IYLAGTASTFKDFRDG---------------------STYDLFIAGVGALCLIFIIMLI---------------------
Q9Z577_STRCO/40-368IELGGGAIALTE....---------------------.SGGSHLAEAVGVAVAAVVLFL---------------------

PF00873

CZCA_RALME/5-1037AVSKAVDEKVASINRT..MPEGVKIVTVYDRTRLVDKAIATVKKNLLEGAVLVIVILFL---------------------
MEXB_PSEAE/1-1028DTAKAIRQTIANLEPF..MPQGMKVVYPYDTTPVVSASIHEVVKTLGEAILLVFLVMYL---------------------
MDTB_ECOLI/12-1023STADSIRQMLPQLTES..LPKSVKVTVLSDRTTNIRASVDDTQFELMMAIALVVMIIYL---------------------
ACRF_ECOLI/1-1029DTAKAIKAKLAELQPF..FPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVMYL---------------------
P74461_SYNY3/10-1047EVVDGVKKRLEELRTEGIIPQAAELTPTLDDSVFIRNSVNNVVVSGLIGTVLAAIAVLL---------------------
O25622_HELPY/6-1014EIITQVYQKLEELKPF..LPNGVSINVFYDRSEFTQKAIATVSKTLIEAVVLIIITLFL---------------------
MDTF_ECOLI/1-1028DTSRAVKEELNRLSAY..FPASLKTVYPYDTTPFIEISIQEVFKTLVEAIILVFLVMYL---------------------
Q55935_SYNY3/9-1024TVTKAVEAVVESLKPT..FPADVQIAQTFRQANFIDSAIRNVSTSLLEGIVIVSVIMLI---------------------
ACRB_ECOLI/1-1030DTAAAIRAELAKMEPF..FPSGLKIVYPYDTTPFVKISIHEVVKTLVEAIILVFLVMYL---------------------
MDTC_ECOLI/3-1009QTVDSIRAKLPELQET..IPAAIDLQIAQDRSPTIRASLEEVEQTLIISVALVILVVFL---------------------
ACRD_ECOLI/1-1027ATAELVLNRLDELAQY..FPHGLEYKVAYETTSFVKASIEDVVKTLLEAIALVFLVMYL---------------------
P73998_SYNY3/2-1028EVARLVKDEMARLAQN..FPEGIEYSVAFDTTEFVQESLSEVVETLLIAVVLVILVILV---------------------
O25328_HELPY/1-1011EIVDRVYEALKRIQA...ISPNYEIRPFLDTTGYIRTSIEDVKFDLVLGAILAVLVVFA---------------------
Q5ZWS7_LEGPH/6-1036TVSQRVAAKMKEINKS..LPEGVEAVTVYNRTLLVNATINTVKKNLLEGALLVCVILFL---------------------
Q9I0Y8_PSEAE/3-1040EISNLVREKMAELKHS..FPQGMDYSIVYDPTIFVRGSIEAVVHTLFEALVLVVLVVIL---------------------

PF02355

SECF_METTH/102-285-------------------------------------QAMNQIYWAIGFAFLFMSVTVF---------------------
SECF_BORBU/108-297-------------------------------------TLRIRSIFLVLGTFILILIYIT---------------------
SECDF_BACSU/540-729-------------------------------------ELARNALYAVAIASIGIIIYVS---------------------
SECF_STRCO/109-305-------------------------------------QIANKAWQGLGIFMVLVVIYLA---------------------
SECF_HAEIN/120-308-------------------------------------ELAQGAVYATLATLAMVLIYVG---------------------
SECF_ECOLI/114-302-------------------------------------DLAQTGAMALMAALLSILVYVG---------------------
SECF_SYNY3/108-301-------------------------------------ALFRSGVLALVISLLGIIIYLT---------------------
SECF_RICPR/110-299-------------------------------------QLIEAGAMAMLFSFLAIMVYIG---------------------
SECF_HELPY/106-293-------------------------------------ELKEKGILSLILALIAIMVYVS---------------------
SECF_RHOCB/123-311-------------------------------------ELVWTAVWSLLAATVVIMFYIW---------------------
SECF_METJA/88-276-------------------------------------KFFEEGFKAVGFAFMFMAIVVY---------------------
SECF_TREPA/222-411-------------------------------------LLVRQALLLVLGALVLIFLYVA---------------------
Q9ZBS8_STRCO/569-757-------------------------------------ELRRDALIALGLALAAQLAYLA---------------------
SECF_RHOS4/117-305-------------------------------------ELIRSAILAVAAACAGIAVYIW---------------------
O84454_CHLTR/1200-1393-------------------------------------KMRTQAVIALFGALGIILFYVS---------------------
SECF_MYCLE/183-379-------------------------------------QITKKVVIALVVFLVLVGLYIT---------------------
SECF_AQUAE/92-279-------------------------------------ELQKKAVFAILTALGGILLYLG---------------------

PF02460

O16307_CAEEL/1-766QVLNNWETSLFDYVENFDHPF...LNMTVNSDAMIAREVRTNGMTCVPFFSFSVAAVVIFIFATNS..REHF........
P91129_CAEEL/47-858YISGEWELELGRMLTQYPEDP..YISITYFHSQTLADELKRNADTLIPRFIISITLLIVFSTLCSL..SFIDG...SFSI
O44978_CAEEL/31-791LAFKDAIDELFQLSKNSSAFE..HVQFTIFSDQVANREMIRGAIEATTLMTIGFFLLLTQVIIVIV..RLSS........
Q18129_CAEEL/47-926QYGIEWRRKLSMWLTDKENPVSELLEFGVNHNMTLPEGLQDVADTLAPKFVGTCAILFTFSFLVSV..VLRKHRTGQVMP
O61894_CAEEL/44-830EMSKIFEQSLTALLENQTTFD.....TSMFSLSILKDEMQKNSTYTMPFISLTILLLLCFTVASCM..TDNW........
Q21883_CAEEL/44-838EDAAEYERMISQYFHFKYDST..HVTPLAMSLTYTGDEVVRTGLTIFPFIGVGFIIMTTFSIITIY..YSSS.....RLD
O16530_CAEEL/48-891EDLRNYEHQILDYIHDEYQSE..HINVYILTDSYITEEIVRAGLTLLPFLVIGFTIMAVFSSIT......FV........
Q19945_CAEEL/49-901EYSSKFSYALETFLNQVYSSD..VITLSFAHYQSLEDGLDENAKAFVPNFVVSFFVLAMYALVSSF..TLKSS..SATKI
Q09938_CAEEL/52-945QLAKFWEDTAEKFVRETYADH.PTIQCHIKHSRIVDQGLTRNANRLKPYFNVTIAVLVLFTAFYSVKWYFRMDHSWPLHI

PF12349

A1CTG5_ASPCL/632-787--VQSKFTLGIVGILI-VLMSVSASVGL-----FSAAG-----VRATLIIAEV-IPFLVL-AVGVDNIFLVVHEFERI--
A1Z6J2_DROME/390-543--FRSRFLLALCSVIT-TAGSLAMSLGL-----CFFFG-----LTISLQSKDI-FPYLVI-LVGLENSLVITKSVVSM--
PTC2_MOUSE/418-570--AQSQGAVGLAGVLL-VALAVASGLGL-----CALLG-----ITFNAATTQV-LPFLAL-GIGVDDIFLLAHAFTKA--
A4S8G2_OSTLU/258-409--VGSRVGVTLAGIVS-IGMAIASAYGI-----GAYCG-----LFFSPLMN.V-LPFLLL-GIGVDDMFVIVNSYDNT--
A5E1Z8_LODEL/460-615--VKTRFTLGLCGIII-ILLSVTASVGL-----FSFIG-----LRSTLIIAEV-IPFLVL-AIGVDNIFLIVHELHKI--
A7RI14_NEMVE/240-393--VKSKWGLAFSAVIT-VIASLIMAAGL-----CTMFG-----LVPTLNSSEI-FPYLVI-MIGVENILVITKSVVST--
A7RNK5_NEMVE/879-1035--LRLKAWLGVAGVIC-VGLSIGVSFGM-----SSAFG-----VFYGPVHS.V-LPFLLL-GIGVDDMFVIVQAWNNL--
A7S0G1_NEMVE/641-795--IDSKFTLGFCGIII-VLCSVICSIGF-----WSYVG-----VPATLIIIEV-IPFLVL-AVGVDNFFIMVQAYQRI--
NPC1_HUMAN/649-803--VDSKVSLGIAGILI-VLSSVACSLGV-----FSYIG-----LPLTLIVIEV-IPFLVL-AVGVDNIFILVQAYQRD--
SCAP_SCHPO/257-410--IRAKFGLTATIFIQ-SGTAYFSTCSL-----LYFFE-----RTGPICPWPM-AYYIII-FMDIENSFRLLRAVIAS--
P91346_CAEEL/298-449--VVTKPILSVLGVSN-AGMGIASAMGM-----LTYLE-----IQYNDIIA.V-MPFLVV-AVGTDNMFLMVASLKRT--
PTR9_CAEEL/288-439--VKSQPFIGFFAMFN-ATMATIASTSL-----LLYLQ-----YPFLPLVF.I-MPFLVV-SIGTDNMFLMLKSWRMT--
Q16VL3_AEDAE/637-791--NESKIILAVGGIVV-VLVSVACSLGF-----FGYLQ-----LATTMLTIEV-IPFLVL-AVGVDNIFMLVHAFQRI--
Q17FP9_AEDAE/355-509--IDSKITLGLGGVII-VLASVVASVGI-----FGYIG-----LPATLIIVEV-IPFLVL-AVGVDNIFILVQTHQRD--
Q17N28_AEDAE/360-513--IRSRLVLAFSAVLT-VLGSLTMSLGM-----CFFFG-----LTISLQSKGV-YPYLVI-LVGLENVLVITKSVLTT--
Q18968_CAEEL/295-448--VASRWGLAFASSFT-VASTLLMTTGI-----CAHLD-----LSTTTWGSEV-YPYIAL-IMGLENTLCITRSVVYT--
Q29GK5_DROPS/626-780--LESRIMLAIGGIVI-VLASVACSLGF-----WGYLD-----VTTTMLAIEV-IPFLVL-AVGVDNIFIMVHTFQRL--
Q2HB50_CHAGB/263-415--VKSRVGLMVTMLAQ-ITASIVSSFTV-----CAIFK-----VDLSHVPLQT-YPFVIL-AISMENSFRLINAVIMT--
A0A0D1C6G9_USTMA/410-564--VHSRFGLAFTGTTQ-LIISMIMSVSI-----CALLG-----IRLTLVPWEL-LPFVIV-VVGSENMYSLTKAIVDT--
B4Q8Q7_DROSI/652-804--IDSKITLGIGGVII-VLASVVSSVGV-----FGYIG-----LPATLIIVEV-IPFLVL-AVGVDNIFILVQTHQRD--
F7ANF6_MACMU/1-147--VKSKWGLALAAVVT-VLSSLLMSVGL-----CTLFG-----LTPTLNGGEI-FPYLVV-VIGLENVLVLTKSVVST--
G1MH71_AILME/663-814--VDSKVTLGLGGVSV-VLGAVTAAMGL-----FSYLG-----VPSSLVILQV-VPFLVL-AVGADNIFIFVLEYQRL--
H3CDQ1_TETNG/587-739--VDSKFLVGLGGILV-VSCAVLSSLGF-----CSWVG-----IPSSLIIVQV-VPFLVL-AVGADNIFIFVLEYQRD--
Q23E28_TETTS/401-549--.HSGFLIGLAGIFI-VIFSIVCSMGF-----MAFIG-----VGMTMISGEV-IPFLIL-AIGVDNMFIISTAVKGC--
Q7S7Y9_NEUCR/315-463--VKSRFGLMATILAQ-IAASIGSSFTI-----CAIFK-----IDLSRVPYYA-YPLVVL-AISMENSFRLINAVIMT--

PF03176

MMPL8_MYCTU/74-402--IYGNPITMVLPLIT-IGMSVVVAQRL.VA.IAGLAG-----LGIANQSIIF.MSGMMV-GAGTDYAVFLISRYHDY--
MMPL8_MYCTU/676-1049--LLRAIVAPLYLIGS-VIVSYLAALGIGVIVFQFLLG-----QEMHWSIPGL.TFVILV-AVGADYNMLLISRLREE--
MMPL4_MYCTU/59-388--VYRSIITVVLLLIT-VGVELTAARGV.VAVLGHSGA-----IGLTTFAVSL.LTSLAI-AAGTDYGIFIIGRYQEA--
MMPL5_MYCTU/63-393--VYRSIITSAIMLTM-VVLGLLATRGG.VAFLGFHRI-----IGLSTFATNL.LVVLAI-AAATDYAIFLIGRYQEA--
MMPL5_MYCTU/612-950--TTRSVVAAAVIVGT-VVLSLGASFGLSVLIWQHILG-----IELHWLVLAM.AVIILL-AVGADYNLLLVARLKEE--
MMPLB_STRCO/48-383--IYRSPLMALVPLLA-VGVAMRVAETL.GAILADAGV-----ITVSSQTASI.MTVLLF-GVGTDYALIITARYRET--
MMPL4_MYCLE/57-385--VYRSFITVILLLFT-VGIESAVARGV.VALLGHTGL-----IGLSTFAVNL.LTSLAI-AAGTDYGIFITGRYQEA--
MMPL7_MYCTU/74-391--ARLSVRAAAIVLLT-ADLSLAVAWPL.AAVVRGHDW-----GTDSVFSWTL.AAVLTI-GTITAATML.......A--
MMPLA_MYCTU/29-358--IYRNPVTMLLPLVT-IGASLMTAQAL.VAGVSLVGG-----LAVSNQAIVL.LSAMIA-GAGTDYAVFLISRYHEY--
MMPL1_MYCTU/52-381--AYRSLSAALIMLLT-VGLELLAVRGI.ISTFAVNDL-----MGLSTFTVNV.LVALTI-AASTDYIIFLVGRYQEA--
MMPL1_MYCTU/600-941--ITRSVVASAVIVGT-VALSLGSAFGLSVLIWQHILH-----MPLHWLVLPM.AIIVML-AVGSDYNLLLIARFQEE--
MMPL9_MYCTU/58-387--VYRSIATTLLILPM-VFIGLGATRGT.IAFLGYHGM-----VGLSTFVVNI.LTALAI-AAGTDYAIFLVGRYQEA--
MMPL9_MYCTU/606-944--ITQSLIASLVIVGT-VLLSLGTAFGLSVLIWQHFVG-----LQVHWTIVAM.SVIVLL-AVGSDYNLLLVSRFKEE--
YDFJ_BACSU/44-362--TFGSLLIAGLPILT-ALIGLGVSIGL...VLIGTQV-----FDIASVSLSL.AGMIGL-AVGIDYALFIFTKHRQF--
YDGH_BACSU/39-360--VFRSVVTPFIPIVV-VGFSYLISQSI.LGILVYNVD-----FPISTFTQTF.LVAILF-GIGTDYCILLLTRFREE--
MMPL6_MYCTU/28-366--ITRSLVAALVIVGT-VALSLGASFGLSVLVWQHLLG-----IQLYWIVLAL.AVILLL-AVGSDYNLLLISRFKEE--
MMPL2_MYCTU/54-382--IYRSVITAVLVLIM-VGIDLGAIRGF.IALLADHNI-----FSLSTFATNL.LVLMAI-AASTDYAIFMLGRYHES--
MMPL2_MYCTU/601-939--ITRSVVAAVVIVGT-VVLSMGASFGLSVLVWQDILG-----IELYWMVLAM.SVILLL-AVGSDYNLLLISRLKEE--
MMPLA_MYCLE/55-391--IYRNPITMLLPLIT-IGASLMTAQAV.VSGVSVLAG-----LAVSNQMIVL.LSAMIA-GAGTDYAVFLISRYHDY--
Q50086_MYCLR/31-369--ITRAFVAAAVIVGT-VALSLGASFGLSVLLWQHILG-----IELHYLVLAM.SVIVLL-AVGSDYNLLLVSRFKQE--
MMPLC_MYCTU/55-384--VYRNLVTMLVPLAT-IGASVVTAQGT.LSGLAEF.G-----LAVNMQAIVF.MSAVMI-GAGTDYAVFLISRYHDY--
MMPLC_MYCTU/658-1001--LLRALVAPIYLIGS-VLISYLSALGIGTLVFQLILG-----QEMHWSLPGL.SFILLV-AIGADYNMLLISRIRDE--
MMPLA_STRCO/46-370--TYRSPLLWLLPMIS-AGMSLVISQAI.VYLLAKNAG-----LTVNAQTAMI.LTVLVL-GAATDYALLLVARYREE--
MMPLA_STRCO/397-682--LLRALVAPLLLIAS-VVLSFFTALGLAALFFNHVFD-----FAGADSAFPLWVFVFLV-ALGVDYNIFLVTRIKEE--
Q9RKC1_STRCO/44-379--TFGSLVSAGLPLLT-ALIGVGIGVSS...ITALASA-----LELGSTTSIL.AMMIGL-AVGIDYALFIVSRYRAE--
Q9RL63_STRCO/44-395--TFGSLAAAGLPLIT-AVVGVALTLAS...IVALGSA-----LGMSTASGDL.AMMIGI-AVGVDYALLVVSRYREE--
MMPLD_STRCO/50-373--VYRSVLLPLVIILS-AVFALALSCAI.VYALADRDV-----VRVDGQVQGI.LSILVI-GAATDYALLLTARFREE--
A0A042QG29_MYCTX/43-376--VYRSAITATVPLLS-VVVSLAVAKPI.VSVLVDRDF-----IGISLFSLGL.SVAVVV-GAGTGFAMFLIGRYHER--
A0A042QG29_MYCTX/595-943--LLRSPLAGLVVVGT-IATSYICALGASVVIWKHILG-----DNLHWSVLPI.AFVLLI-SVGSAYNLLFALRIREE--
Q9XCF5_MYCAV/55-384--VYRSVITVILLLLI-VGLELQIARGM.VALLGHLGV-----VGLTTFAVNL.LVAAVI-ATGTDYGIFFVGRYQEA--
Q9XCF5_MYCAV/604-943--MTRSFIAAMVIVGT-VLLSLGASFGLSVLVWQYLLH-----MQLNWTVLPT.SVIVLL-ALGPDYNLLLVSRMKEE--
Q9XCF6_MYCAV/51-382--VYRSVTTVVLLLLT-VGIEVFAARGV.IAFVANNNL-----MPLSTFAVNL.LVALAM-AAGTDYAIFFFGRYQEA--
Q9XCF6_MYCAV/601-939--LTRSFIAALIIVGT-VTLSLGASFGLSVLIWQYIFG-----IQLYWMVLPM.SVIVLL-AVGSDYNLLLVSRMKEE--
Q9Z577_STRCO/40-368--AFGSVAAALLPIAT-ALVSVGTAYAG...ITLLGHA-----MTVADFAPML.GTLIGL-GVGIDYALFIVTRHRRG--

PF00873

CZCA_RALME/5-1037--FLGNIRAALITATI-IPLAMLFTFTG-----MVNYK-----ISANLMSLG--ALDF..-GIIIDGAVVIVENCVRR--
MEXB_PSEAE/1-1028--FLQNFRATLIPTIA-VPVVLLGTFGV-----LAAFG-----FSINTLTMF--GMVLAI-GLLVDDAIVVVENVERV--
MDTB_ECOLI/12-1023--FLRNIPATIIPGVA-VPLSLIGTFAV-----MVFLD-----FSINNLTLM--ALTIAT-GFVVDDAIVVIENISRY--
ACRF_ECOLI/1-1029--FLQNMRATLIPTIA-VPVVLLGTFAI-----LAAFG-----YSINTLTMF--GMVLAI-GLLVDDAIVVVENVERV--
P74461_SYNY3/10-1047--FLGSLRQTLIIVLA-IPLATMAAIIV-----MKAFG-----LSLNVFSLG--GLALGV-GIVVDNSIVMLETIAEG--
O25622_HELPY/6-1014--FLGNLRASVAVGVI-LPLSLSVAFIF-----IKFSD-----LTLNLMSLG--GLVIAI-GMLIDSAVVVVENAFEK--
MDTF_ECOLI/1-1028--FLQNFRATIIPTIA-VPVVILGTFAI-----LSAVG-----FTINTLTMF--GMVLAI-GLLVDDAIVVVENVERV--
Q55935_SYNY3/9-1024--FLMNWRTAAITLTA-IPLSLLIGLMF-----MKAWG-----LGINTMTLG--GLVVAI-GSVVDDSIVDMENCYRG--
ACRB_ECOLI/1-1030--FLQNFRATLIPTIA-VPVVLLGTFAV-----LAAFG-----FSINTLTMF--GMVLAI-GLLVDDAIVVVENVERV--
MDTC_ECOLI/3-1009--FLRSGRATIIPAVS-VPVSLIGTFAA-----MYLCG-----FSLNNLSLM--ALTIAT-GFVVDDAIVVLENIARH--
ACRD_ECOLI/1-1027--FLQNFRATLIPTIA-VPVVLMGTFSV-----LYAFG-----YSVNTLTMF--AMVLAI-GLLVDDAIVVVENVERI--
P73998_SYNY3/2-1028--FLQDWRSALIPALT-IPLALIGTFAF-----VKVFN-----FSINSLTLF--GLTLAT-GLVVDDAIIVVEQISRF--
O25328_HELPY/1-1011--FLRNGTITLVSAIS-IPISIMGTFAL-----IQWMG-----FSLNMLTMV--ALTLAI-GIIIDDAIVVIENIHKK--
Q5ZWS7_LEGPH/6-1036--FLGNVRAALITAMV-IPLSMLLTITG-----MVTNQ-----ISANLMSLG--ALDF..-GLIVDGAVIIVENCIKH--
Q9I0Y8_PSEAE/3-1040--FLQTWRASIIPLAA-VPVSLIGTFAV-----MHMLG-----FSLNALSLF--GLVLAI-GIVVDDAIVVVENVERN--

PF02355

SECF_METTH/102-285--IIFRDPVPSLAVILAAASDIIIAVGG-----MSLFG.....IPLSLASVG--AILMLI-GYSVDTDILLTTRVLKR..
SECF_BORBU/108-297--LRFKLSYAIASILS.IFHDIFFIVAF-----LGVFR.....IEINSYIIV--AILTII-GYSLNDTIIIFDRIRDN..
SECDF_BACSU/540-729--IRFEYKMAIAAIAS.LLYDAFFIVTF-----FSITR.....LEVDVTFIA--AILTII-GYSINDTIVTFDRVREHMK
SECF_STRCO/109-305--IAFEWRMALAAFVA.LIHDITITVGI-----YALVG.....FEVTPGTVI--GLLTIL-GYSLYDTVVVFDSLKEQTR
SECF_HAEIN/120-308--SRFEWRLGFGSIAS.LAHDVIITLGV-----FSALQ.....IEIDLTFVA--AILSVV-GYSINDSIVVFDRVREN..
SECF_ECOLI/114-302--FRFEWRLAAGVVIA.LAHDVIITLGI-----LSLFH.....IEIDLTIVA--SLMSVI-GYSLNDSIVVSDRIREN..
SECF_SYNY3/108-301--IRFQLDYAVFAIIA.LLYDALITMGA-----FAIFGLV.GGVEVDSLFLV--ALLTII-GFSVNDTVVIYDRVRET..
SECF_RICPR/110-299--VRFEWYFGFGILIA.LVHDVILALGF-----MSMTK.....LDFNLSTIA--AVLTII-GYSVNDSVVIYDRIREN..
SECF_HELPY/106-293--FRYEWRFALASVIA.LVHDVILVASS-----VIVFK.....IDMNLEVIA--ALLTLI-GYSINDTIIIFDRIREE..
SECF_RHOCB/123-311--VRFEWQFALGAVVA.LVHDVLLTVGL-----FAVLQ.....LKFDLTTVA--ALLTIT-GYSINDTVVVFDRLREN..
SECF_METJA/88-276--LYFRNPVPSGAIILSALSDIIMALGA-----MSLLG.....IELSSATIA--ALLMVI-GYSVDSDILLTTRVLKR..
SECF_TREPA/222-411--LRFRWFFALGAIVA.LVHDACIMVSF-----MVWFG.....LEFNSASIA--AILTII-GYSINDTVVVFDRVRQT..
Q9ZBS8_STRCO/569-757--VRFRLLFGTAAVGA.LAHDVVILVGV-----FAWLG.....KPIDGVFLA--ALLTVI-GYSVNDSVVLFDRIREL..
SECF_RHOS4/117-305--LRFEWQFALGSVAA.LIHDVLVTIGV-----FALFQ.....IKFDLTTVA--ALLTVL-GYSINDTVVVFDRLREN..
O84454_CHLTR/1200-1393--LRFEWRYAFSAICA.LMHDLLATCAV-----LVALHFFLQRIQIDLQAIG--ALMTVL-GYSLNNTLIIFDRIRED..
SECF_MYCLE/183-379--VRYERYMAISALTT.MCFDLTVTAGV-----YSLVG.....FEVTPATVI--GLLTIL-GFSLYDTVIVFDKVEENTH
SECF_AQUAE/92-279--VRFQPVWGFGAILA.LAHDVITVLGA-----YSITQ.....REVNLEVVS--AILVVA-GYSVADTVVIFDRIREN..

PF02460

O16307_CAEEL/1-766.VFSHNVVMAILGIAG-PLMATGTAFGF-----LFLFG-----FPFNSITLV--MPFLII.GVGCDDVFIIIHAMRKT--
P91129_CAEEL/47-858DWVLSKPILSILGVVS-AGIAILTGVGF-----LSLMG-----MPYNDIVGV--MPFLVL.AVGVDNMFLMVAAVRRT--
O44978_CAEEL/31-791..VKMAFYLVATSLLT-PMAATVASFGA-----ICWMG-----FPSFSIQCV--TPFLVLG.IGVDDAFILLHRWKHH--
Q18129_CAEEL/47-926DWVRSKPLVAAAGLMT-PIMATVTSFGL-----ILWCG-----FLYNAIVNV--SPFLIL.CIGIDDLFIMCAEWHRT--
O61894_CAEEL/44-830..VTSKPIEAMIGILV-SSMAIVSAGGL-----LFALG-----VPFINQVTV--MPFIAL.AIGVDDVYVMLGAWQDT--
Q21883_CAEEL/44-838QWSVHKVSEAILACVC-PLLATSSALGT-----LFWFG-----FRFGTILCV--TPFLIL.AIGVDDAYLQVHACMRL--
O16530_CAEEL/48-891......PILAVMACVC-PFMACGASLGA-----MFFIG-----FRFGSILCV--TPFLVL.AIGVDDSYLMANAWQRI--
Q19945_CAEEL/49-901DWISSKPWLAAAGMFS-TVLSIISAFGF-----LFILG-----VRYNVINTI--IPFLII.AIGIDDMFLMNACWDQT--
Q09938_CAEEL/52-945DWLRSKPMLALGGVLS-SVLAILSGIGL-----LLWFG-----MFFAEITLI--APFLVL.SIGVDDMFIAVAAWHNT--

PF12349

A1CTG5_ASPCL/632-787-NVSHPDE.E--------IDE----RVARAVGRIGPSIFLSAVT-----ETVAFA.L---GVFVG--MP--AVKN-FAVY
A1Z6J2_DROME/390-543-DETFDV...--------.KI----RVAQALSKEGWHISKTLLT-----EITILT.I---GLATF--VP--VIQE-FCIF
PTC2_MOUSE/418-570-PPDTPL...--------.PE----RMGECLRSTGTSVALTSVN-----NMVAFF.M---AALVP--IP--ALRA-FSLQ
A4S8G2_OSTLU/258-409-EARVDP...--------.VE----RMGRSLRVAGMSITVTSAT-----DVIAFL.I---GSSTS--LP--ALKN-FCFY
A5E1Z8_LODEL/460-615-SEHEPDL.D--------IPI----RIAFAMRNIGPSCFISAIL-----QISMFL.L---ATAVD--MP--AVKN-FAIY
A7RI14_NEMVE/240-393-PVDLDV...--------.KH----RVAQGLSKEGKYMLKNLLW-----EILVLG.L---GYLTY--VH--AIQE-FALF
A7RNK5_NEMVE/879-1035-TPEEHKTKE--------VHE----RIALTLQHAGCSITITSLT-----DFLAFL.I---GASTV--LP--GLQS-FCIY
A7S0G1_NEMVE/641-795-NRYSNEP..--------VSK----KISCALGEVAPSMLLSSLS-----ESVAFG.F---GAMSD--MP--AVKV-FSLY
NPC1_HUMAN/649-803-ERLQGET..--------LDQ----QLGRVLGEVAPSMFLSSFS-----ETVAFF.L---GALSV--MP--AVHT-FSLF
SCAP_SCHPO/257-410-PQTKRV...--------.PS----RIMEGFSSTIIASFSSLLK-----KLLTLFVL---S.FFV--YP--LVQE-FCLF
P91346_CAEEL/298-449-DRNLKY...--------.DQ----RIAECMADAAVSILITALT-----DALSFG.V---GTITT--IP--AVQI-FCIY
PTR9_CAEEL/288-439-KKSSNE...--------.EQ----RYIHALTESAASLFLTSLT-----DGLSFA.I---GSISD--FH--AVRV-FCTY
Q16VL3_AEDAE/637-791-DRVQTPE..--------TDK----AIGKALGQIGPSILLTSAS-----ECCCFA.I---GGLSP--MP--AVNT-FAWY
Q17FP9_AEDAE/355-509-TKKPTET..--------HAE----HIGRILGRVGPSILLTAVS-----ESCCFF.L---GGLSD--MP--AVRA-FALY
Q17N28_AEDAE/360-513-DSNLDV...--------.KI----RLAQGLSREGWSITKNLLT-----EITILT.I---GLCTF--VP--VIQE-FCIF
Q18968_CAEEL/295-448-SPSLDV...--------.SS----RIAHGLSQEGYKLTKYYIL-----ELLALL.I---GFLTR--IS--DIQE-FCQF
Q29GK5_DROPS/626-780-DHSRFET..--------THE----AIGEAIGQVGPSILQTAGS-----EFACFA.I---GALSD--MP--AVKT-FAMY
Q2HB50_CHAGB/263-415-SSAISI...--------.SD----RIGEAFGTTAHIAIASPIQ-----NSLILYGL---S.KTG--SL--GVSS-FCAF
A0A0D1C6G9_USTMA/410-564-PLSLTV...--------.SS----RIAHGLGKVGVPITLTTLA-----DILLLLVI---ALFIE--VR--AVRE-FCIF
B4Q8Q7_DROSI/652-804-QRKPNET..--------LEQ----QVGRILGKVGPSMLLTSLS-----ESFCFF.L---GGLSD--MP--AVRA-FALY
F7ANF6_MACMU/1-147-PVDLEV...--------.KL----RIAQGLSSESWSIMKNMAT-----ELGIIL.I---GYFTL--VP--AIQE-FCLF
G1MH71_AILME/663-814-PRRPGER..--------REA----HIGRALGRVAPSMLLCSLS-----EAICFF.L---GALTP--MP--AVRT-FALT
H3CDQ1_TETNG/587-739-VRRPGEK..--------REE----QIGRILGNVAPSMLLCSLS-----ESICFF.F---GALST--MP--AVKS-FALY
Q23E28_TETTS/401-549-HGENL....--------.LE----KIKGGMTEVGPSITAAAVS-----EILAFM.V---GTFTN--IP--ALTT-FCIQ
Q7S7Y9_NEUCR/315-463-SSSISI...--------.SD----RIGEAFGQTAYVAILNRLQ-----NLAILLGL---S.RIT--FP--GVAA-FCTF

PF03176

MMPL8_MYCTU/74-402-LRQGADS-----------DQ....AVKKALTSIGKVIAASAAT-----VAITFL-G...MVFTQ--LG--ILKT.VGPM
MMPL8_MYCTU/676-1049-AVLGVRS-----------......GVIRTVASTGGVITAAGLI-----MAASMY-G...LVFAS--LG--SVVQ.GAFV
MMPL4_MYCTU/59-388-RQAGEDK-----------EA....AYYTMYRGTAHVILGSGLT-----IAGATF-C...LSFAR--MP--YFQT.LGIP
MMPL5_MYCTU/63-393-RGLGQDR-----------ES....AYYTMFGGTAHVVLGSGLT-----IAGATF-C...LSFTR--LP--YFQT.LGVP
MMPL5_MYCTU/612-950-IHAGINT-----------......GIIRAMGGSGSVVTAAGLV-----FAFTMM-S...FAVSE--LT--VMAQ.VGTT
MMPLB_STRCO/48-383-LLDEPDR-----------AR....AMQAAVRRTAESVLASAST-----IVLAMF-A...LLVAV--SP--ALHG.FGPY
MMPL4_MYCLE/57-385-RQANENK-----------EA....AFYTMYRGTFHVILGSGLT-----ISGATF-C...LSFAR--MP--YFQT.LGVP
MMPL7_MYCTU/74-391-ARLGSDA-----------GH....SAAPTYRDSLPAFALPGAC-----VAIFTG-P...LLLAR--TP--ALHG.VGTA
MMPLA_MYCTU/29-358-VRLGEHP-----------ER....AVQRAMMSVGKVIAASAAT-----VGITFL-G...MRFAK--LG--VFST.VGPA
MMPL1_MYCTU/52-381-RATGQNR-----------EA....AYYTMFGGTAHVVLASGLT-----VAGAMY-C...LGFTR--LP--YFNT.LASP
MMPL1_MYCTU/600-941-IGAGLKT-----------......GMIRAMAGTGRVVTIAGLV-----FAFTMG-S...MVASD--LR--VVGQ.IGTT
MMPL9_MYCTU/58-387-RHIGQNR-----------EA....SFYTMYRGTANVILGSGLT-----IAGATY-C...LSFAR--LT--LFHT.MGPP
MMPL9_MYCTU/606-944-VGAGLKT-----------......GIIRAMAGTGAVVTSAGLV-----FAFTMA-S...MAVSE--LR--VIGQ.VGTT
YDFJ_BACSU/44-362-LGEGIQK-----------NE....SIARAVGTAGSAVVFAGLT-----VIVALC-G...LTVVN--IP--FMSA.MGLT
YDGH_BACSU/39-360-LANGHDK-----------KE....AALIAYRTGGKTLFISGFA-----VLIGFS-A...LGFAK--FA--IFQSAVGVA
MMPL6_MYCTU/28-366-IGAGLNT-----------......GIIRAMAGTGGVVTAAGLV-----FAATMS-S...FVFSD--LR--VLGQ.IGTT
MMPL2_MYCTU/54-382-RYAGEDR-----------ET....AFYTMFHGTAHVILGSGLT-----IAGAMY-C...LSFAR--LP--YFET.LGAP
MMPL2_MYCTU/601-939-IGAGLNT-----------......GIIRAMAGTGGVVTAAGMV-----FAVTMS-L...FVFSD--LR--IIGQ.IGTT
MMPLA_MYCLE/55-391-IRMGSGS-----------AQDAGCAVRQALISLGKVIAASAAT-----VGITFL-G...MSFTK--IR--VFST.VGPA
Q50086_MYCLR/31-369-IQAGLKT-----------......GIIRSMGGTGKVVTNAGLV-----FAFTMA-S...MVVSD--LR--VIGQ.VGTT
MMPLC_MYCTU/55-384-VRHGEKS-----------DM....AVKKALMSIGKVITASAAT-----VAVTFL-A...MVFTK--LE--VFSA.VGPA
MMPLC_MYCTU/658-1001-SPHGIRI-----------......GVIRTVGSTGGVITSAGLI-----FAASMF-G...LVGAS--IN--TMAQ.AGFT
MMPLA_STRCO/46-370-LRRHEDR-----------HE....AMAVALRRAGPAIVASAAT-----VAVSML-V...LLLAA--LN--STKG.LGPV
MMPLA_STRCO/397-682-SDRLGTR-----------Q.....GALKGLTSTGGVITAAGLV-----LAGTFA-A...LATLP--LV--FIAE.LGFT
Q9RKC1_STRCO/44-379-LAEGRER-----------EE....AAGRAVGTAGSAVVFAGLT-----VVIALV-G...LAVVN--IP--MLTK.MGIA
Q9RL63_STRCO/44-395-RAEGHDA-----------RE....AAGLAVGTAGSAVVFAGLT-----VVIALA-G...LSVIG--VP--SLTK.MGLA
MMPLD_STRCO/50-373-LARHPDR-----------FG....AVRAALRDSWGAVVASAAT-----VALGLL-A...LLLSD--LT--NNRA.LGPV
A0A042QG29_MYCTX/43-376-RRQHIAP-----------AA....ALADAYRGVAPAIAGATFI-----VVTSLG-AVGWLSLAR--IG--MFAT.TGIL
A0A042QG29_MYCTX/595-943-SPAGPRT-----------......SVIRAFAATGMVVTAAGIV-----FGTTMF-A...LAAST--SL--SVAQ.IGVT
Q9XCF5_MYCAV/55-384-RQAGESR-----------EE....AFYTTFNGVAKVVLASGLT-----IAGAVL-C...LSFTR--LP--YFQP.LGIP
Q9XCF5_MYCAV/604-943-LAAGIHT-----------......GIIRAMGGTGKVVTNAGLV-----FAFTMG-A...MVVSD--LR--SIGQ.VGTT
Q9XCF6_MYCAV/51-382-RQAGEDR-----------AT....AYFTTYRSVAPVVLGSGLT-----IAGAML-C...LSFTR--MP--IFQT.MGLP
Q9XCF6_MYCAV/601-939-IAAGINT-----------......GIIRAMGGTGKVVTNAGLV-----FAFTMA-S...MVVSD--LR--IIGQ.VGTT
Q9Z577_STRCO/40-368-LKRGLSV-----------AD....AAADAVATTGRAVVFAGAT-----VCIALL-G...MLILR--LS--FLNG.VAVA

PF00873

CZCA_RALME/5-1037-LAH.AQEHHGRPLTRSERFH----EVFAAAKEARRPLIFGQLI-----IMIVYLPI---FALTG--VEGKMFHP-MAFT
MEXB_PSEAE/1-1028-MAE.EGLSP.........RE----AARKSMGQIQGALVGIAMV-----LSAVFLPM---AFFGG--STGVIYRQ-FSIT
MDTB_ECOLI/12-1023-IEK..GEKP.........LA----AALKGAGEIGFTIISLTFS-----LIAVLIPL---LFMGD--IVGRLFRE-FAIT
ACRF_ECOLI/1-1029-MME.DKLPP.........KE----ATEKSMSQIQGALVGIAMV-----LSAVFIPM---AFFGG--STGAIYRQ-FSIT
P74461_SYNY3/10-1047-AGMTPGKVNPLPLTKGEMRN----QAIASSQTVESALVASTST-----NLVAVLPF---LMIGG--FIALIFNE-LILT
O25622_HELPY/6-1014-LSANTKTTK.........LH----AIYRSCKEIAVSVVSGVVI-----IIVFFVPI---LTLQG--LEGKMFRP-LAQS
MDTF_ECOLI/1-1028-IAE.DKLPP.........KE----ATHKSMGQIQRALVGIAVV-----LSAVFMPM---AFMSG--ATGEIYRQ-FSIT
Q55935_SYNY3/9-1024-LRTNQAEGNPK.....HPLR----VVYETSVEVRLAVIFSTVI-----IVVVFAPI---FSLTG--VEGRIFAP-MGLA
ACRB_ECOLI/1-1030-MAE.EGLPP.........KE----ATRKSMGQIQGALVGIAMV-----LSAVFVPM---AFFGG--STGAIYRQ-FSIT
MDTC_ECOLI/3-1009-LEA..GMKP.........LQ----AALQGTREVGFTVLSMSLS-----LVAVFLPL---LLMGG--LPGRLLRE-FAVT
ACRD_ECOLI/1-1027-MSE.EGLTP.........RE----ATRKSMGQIQGALVGIAMV-----LSAVFVPM---AFFGG--TTGAIYRQ-FSIT
P73998_SYNY3/2-1028-IKV.KHEDP.........QE----AAQEAMGELTGAVIATSLV-----LMAVFIPV---AFFPG--TTGALYQQ-FALT
O25328_HELPY/1-1011-LEM..GMSK.........RK----ASYEGVREIGFALVAISAM-----LLSVFVPI---GNMKG--IIGRFFQS-FGIT
Q5ZWS7_LEGPH/6-1036-LGEQQHALQRILN.LEERLK----TIAYATTEVIRPSIFGVFI-----ITVVYLPI---LTLTG--VEGKMFLP-MAET
Q9I0Y8_PSEAE/3-1040-IGL..GLKP.........VE----ATKRAMREVTGPIIATALV-----LCAVFIPT---AFISG--LTGQFYRQ-FALT

PF02355

SECF_METTH/102-285..RK...GTI---------NE----RALGAMKTGVTMSIAAIAS....MAALYLVTV---FVMPE....ARVLSD-IAAV
SECF_BORBU/108-297.VKRLTDNTF---------LN----VLNISISQTLSRTVLTSVT.....TFVAVFSI---YVFTE....G.SIKD-FSLV
SECDF_BACSU/540-729KRKPKTFADL---------NH----IVNLSLQQTFTRSINTVLT.....VVIVVVTL---LIFGA.....SSITN-FSIA
SECF_STRCO/109-305DITKQTRWTY---------AE----IANRSINSTLVRSINTTVV.....ALLPVAGL---LFIGGGVLGAGMLND-ISLS
SECF_HAEIN/120-308.FRKIRRLDT---------ID----IIDISLTQTLSRTIITSVT.....TLVVVMAL---FFFGG.....PSIHN-FSLA
SECF_ECOLI/114-302.FRKIRRGTP---------YE----IFNVSLTQTLHRTLITSGT.....TLMVILML---YLFGG.....PVLEG-FSLT
SECF_SYNY3/108-301.LERHSDWDI---------NH----VVDDAVNQTLTRSINTSLT.....TSLPLVAI---FLFGG.....DSLKF-FALA
SECF_RICPR/110-299.LRKYHKKNI---------TE----IINLSINETLSRTILTVIT.....TLLANLAL---ILFGG.....KAIHS-FSVL
SECF_HELPY/106-293.MLSQKTKNA---------TQ----AIDEAISSTLTRTLLTSLT.....VFFVVLIL---CVFGS.....KIIIG-FSLP
SECF_RHOCB/123-311.LIKYKTMPL---------RD----VMNLSVNETLSRTVMTGMT.....TLLALVPM---LIWGG.....DVIRG-FVFA
SECF_METJA/88-276.LTKSFDETV---------KE----AMKTGLTMTLT.TITAMLI......LLIVVKL---FIPVA.....DILAN-IATV
SECF_TREPA/222-411.ILLDPIASV---------TT----VLDRSQTDMLTRTVVTTVT.....TLLAALML---YVFTE.....GGSRD-FSLA
Q9ZBS8_STRCO/569-757.LGKERKAPF---------DR----LTNDAILQTLPRTVNTGMG.....AVLILASL---AILAD.....DSLTD-FALA
SECF_RHOS4/117-305.LVKYKTMPL---------RD----VMNLSVNETLSRTIMTLMT.....TLIALVSL---LVFGG.....DVIRG-FVFA
O84454_CHLTR/1200-1393.RREKLFTPM---------PI----LINDALQKTLGRTVMTTAT.....TLSVLVIL---LFVGG.....GSIFN-FAFI
SECF_MYCLE/183-379GFQHTTRRTF---------AE----QANLAINQTFMRSINTSLISVLPVLALMVVAV---WLLGV.....GTLKD-LALV
SECF_AQUAE/92-279.LRKKKGFTL---------EE----IMDLSINQTLSRTIMTSLT.....TLVTALTL---FILGG.....YALSN-IMFA

PF02460

O16307_CAEEL/1-766--DKSES...........LED----RIAETMEEAGPSITVTSAT-----NCLSFA-I---GIATP--TP--AISL-FCLY
P91129_CAEEL/47-858--SRTHT...........VHE----RMGECLADAAVSILITSST-----DVLSFG-V---GAITT--IP--AVQI-FCVY
O44978_CAEEL/31-791--IAITD...........TPR----RLEQVIVDVGPSITITSLT-----NIIAFG-I---GFLTP--TP--QMSL-FCLT
Q18129_CAEEL/47-926--NPQHS...........PEK----RIGKTLSEAAVAISITSLT-----DIATFA-M---GCYTT--LP--GVQM-FCMY
O61894_CAEEL/44-830--RRTLD...........AKK----RMGLALEEAGSAITVTSLT-----SVLSFG-I---GTYST--TP--AIAI-FCKF
Q21883_CAEEL/44-838--TAEDSS........MTKRE----KIARMLVEVGPSIAITSMT-----NLFAFL-V---GIYTP--TP--EISL-FCAG
O16530_CAEEL/48-891--TCHRRKHARFESVNVELKN----RITEMFIETGPSITITTIT-----NALAFG-I---GATTP--AA--EIQL-FSIG
Q19945_CAEEL/49-901--SKSLS...........VPE----RMSKTLSHAGVAVTITNVT-----DVMSFA-I---GCITD--LP--GIQF-FCIY
Q09938_CAEEL/52-945--EMKYPGRS.....PKVMKK----RMIEAMSESAVAIFITSFT-----DVLSFG-A---GTITD--II--AVQG-FCAM

PF12349

A1CTG5_ASPCL/632-787AAGAVFINAILQMTMF-VSVLAL-----------NQRRV-----------------------------------------
A1Z6J2_DROME/390-543AIVGLLSDFMLQMLLF-STILAM-----------NIKRT-----------------------------------------
PTC2_MOUSE/418-570AAIVVGCNFAAVMLVF-PAILSL-----------DLRRR-----------------------------------------
A4S8G2_OSTLU/258-409AALGIFFDYLYQITFF-TAFLSI-----------DERRK-----------------------------------------
A5E1Z8_LODEL/460-615SAGAVAINFILQMTCF-VSLLAL-----------DQQRM-----------------------------------------
A7RI14_NEMVE/240-393ALVGLLTDFFLQVFMF-ATILSI-----------DIRRM-----------------------------------------
A7RNK5_NEMVE/879-1035AGLGILIDFILQITLF-SAFLTL-----------DGRRE-----------------------------------------
A7S0G1_NEMVE/641-795ASFAVAVDFILQITWF-VALMSL-----------DAKRQ-----------------------------------------
NPC1_HUMAN/649-803AGLAVFIDFLLQITCF-VSLLGL-----------DIKRQ-----------------------------------------
SCAP_SCHPO/257-410LACSFVVSFLLHGSFF-LAVLSV-----------DIRRL-----------------------------------------
P91346_CAEEL/298-449TMCALLLTFAYQLTFF-CAILVY-----------YTRIE-----------------------------------------
PTR9_CAEEL/288-439CAMAILFMFLFQVTFF-NAVMSL-----------CCRRE-----------------------------------------
Q16VL3_AEDAE/637-791ATVALFVDFVLQITAF-VALMAL-----------DERRV-----------------------------------------
Q17FP9_AEDAE/355-509AGMALLIDFFLQITCF-VSLLAL-----------DTARQ-----------------------------------------
Q17N28_AEDAE/360-513AIVGLVSDFFLQMMIF-STVLAL-----------NIKQV-----------------------------------------
Q18968_CAEEL/295-448SVICVTVDFYMQLFFY-APCLTF-----------DLQRL-----------------------------------------
Q29GK5_DROPS/626-780AAAAILFDFLLQITAF-VALMAI-----------DQRRV-----------------------------------------
Q2HB50_CHAGB/263-415ATIATFFDFFYLATFF-LAVLSV-----------DVRQR-----------------------------------------
A0A0D1C6G9_USTMA/410-564AIFSLIMDWFLQMTFF-VTVLSI-----------DMQRL-----------------------------------------
B4Q8Q7_DROSI/652-804AGVALIIDFLLQITCF-VSLFTL-----------DTKRR-----------------------------------------
F7ANF6_MACMU/1-147AVVGLVSDFFLQMLFF-TTVLSI-----------DIRRM-----------------------------------------
G1MH71_AILME/663-814SGFAVVLDFLLQVSAF-VALLSL-----------DSRRQ-----------------------------------------
H3CDQ1_TETNG/587-739AAVAILLDFALQMTAF-VALLSL-----------DCRRQ-----------------------------------------
Q23E28_TETTS/401-549AAIAVFFDYIFQITAF-VAILAW-----------DEERK-----------------------------------------
Q7S7Y9_NEUCR/315-463AAVAIVFDFLYLATFF-LAVLSV-----------DVRQR-----------------------------------------

PF03176

MMPL8_MYCTU/74-402LGISVAVVFFAAVTLL.PALMVL...........TGRRG.WI.-------------------------------------
MMPL8_MYCTU/676-1049LGTGLLLDTFLVRTVTVPAIAVL...........VGQA.....-------------------------------------
MMPL4_MYCTU/59-388CAVGMLVAVAVALTLG.PAVLHV...........GSRFG.LF.-------------------------------------
MMPL5_MYCTU/63-393LAIGMVIVVAAALTLG.PAIIAV...........TSRFGKLL.-------------------------------------
MMPL5_MYCTU/612-950IGMGLLFDTLIVRSFMTPSIAAL...........LGKW.....-------------------------------------
MMPLB_STRCO/48-383LALGVAVMALVAFTFI.PALVLL...........LGRSVFWPG-------------------------------------
MMPL4_MYCLE/57-385CAVGMLIAVAVALTLG.PAVLTV...........GSRFG.LF.-------------------------------------
MMPL7_MYCTU/74-391.GLGVFVALAASLTVL.PALIAL...........AGASRQLP.-------------------------------------
MMPLA_MYCTU/29-358LAIGIAVSFLAAVTLL.PAILVL...........ASPRG.WV.-------------------------------------
MMPL1_MYCTU/52-381CAIGLVTVMLASLTLA.PAIIAV...........ASRFG.LF.-------------------------------------
MMPL1_MYCTU/600-941IMIGLLFDTLVVRSYMTPALATL...........LGRW.....-------------------------------------
MMPL9_MYCTU/58-387LAIGMLVSVAAALTLA.PAIIAI...........AGRFG.LL.-------------------------------------
MMPL9_MYCTU/606-944IGLGLLFDTLVVRSFMTPSIAAL...........LGRW.....-------------------------------------
YDFJ_BACSU/44-362AGLSVLMAVLASITLV.PAVLSI...........AGKRMIPK.-------------------------------------
YDGH_BACSU/39-360VGVGILMIIL..YTLL.PLFMVT...........LGEK..LF.-------------------------------------
MMPL6_MYCTU/28-366IGLGLLFDTLVVRAFMTPSIAVL...........LGRW.....-------------------------------------
MMPL2_MYCTU/54-382IAIGMLVAVLAALTLG.PAVLTV...........GSFFK.LF.-------------------------------------
MMPL2_MYCTU/601-939IGLGLLFDTLVVRSFMTPSIAAL...........LGRW.....-------------------------------------
MMPLA_MYCLE/55-391LAIGIAVAFLAAVTLM.PALLVL...........AGTRG.WV.-------------------------------------
Q50086_MYCLR/31-369IGLGLLFDTLIVRSFMMPSIAAL...........LGRW.....-------------------------------------
MMPLC_MYCTU/55-384IAVAITVSLLGAVTLL.PAILTL...........TGRRG.WI.-------------------------------------
MMPLC_MYCTU/658-1001IGIGIVLDTFLVRTVTVPALTTM...........IGRA.....-------------------------------------
MMPLA_STRCO/46-370CAVGVLVGLLSMMTLL.PALLVI...........FGRWVFWPA-------------------------------------
MMPLA_STRCO/397-682VAVGVLLDTMIVRSVLVTALTLD...........VGRW.....-------------------------------------
Q9RKC1_STRCO/44-379AAGTVAIAVLIALTMI.PALLGY...........AGRRVKPAG-------------------------------------
Q9RL63_STRCO/44-395AAGAVVIAVLITLTLV.PALCGFWPDALLARRVRKGRSAPPAR-------------------------------------
MMPLD_STRCO/50-373GAIGIVCSVLSTLTFL.PAVLVL...........LGRAAYWPA-------------------------------------
A0A042QG29_MYCTX/43-376CSIGVLAVGLAALTLT.PALVAL...........ASRANLLK.-------------------------------------
A0A042QG29_MYCTX/595-943VGMGLLLDALVIRGFVLPALMVL...........LGRW.....-------------------------------------
Q9XCF5_MYCAV/55-384VAVGISIAVLVALTLG.PALLAA...........GARFG.LF.-------------------------------------
Q9XCF5_MYCAV/604-943IGLGLLFDTLIVRAFMTPSVAAL...........LGRW.....-------------------------------------
Q9XCF6_MYCAV/51-382CSVGMLISVFIALTLV.PAVLTV...........GGGFG.LF.-------------------------------------
Q9XCF6_MYCAV/601-939IGLGLMFDTLIVRSFMTPTIAAL...........FGRW.....-------------------------------------
Q9Z577_STRCO/40-368ASLTVLLTVAASVTLL.PALLSY...........IGPRALSR.-------------------------------------

PF00873

CZCA_RALME/5-1037VVLALLGAMILSVTFV-PAAVAL-----------FIGERVAEKE..................NRLMLWAKRRYEPLLEKS
MEXB_PSEAE/1-1028IVSAMALSVIVALILT-PALCAT-----------MLKPIEKGDHGEH.......KGGFFGWFNRMFLSTTHGYERGVASI
MDTB_ECOLI/12-1023LAVAILISAVVSLTLT-PMMCAR-----------MLSQESLRKQN...........RFSRASEKMFDRIIAAYGRGLAKV
ACRF_ECOLI/1-1029IVSAMALSVLVALILT-PALCAT-----------LLKPVSAEHHEN........KGGFFGWFNTTFDHSVNHYTNSVGKI
P74461_SYNY3/10-1047ISFAVAASILVAVTLV-PMAASR-----------LLAIRRRSGLGN.........WLFFREFNRRFAGATAAYARFLSIL
O25622_HELPY/6-1014IVYALLGTLVLSITII-PVVSSL-----------VLKATPHSE...................TFLTRFLNRIYAPLLEFF
MDTF_ECOLI/1-1028LISSMLLSVFVAMSLT-PALCAT-----------ILKAAPEGGHKP.........NALFARFNTLFEKSTQHYTDSTRSL
Q55935_SYNY3/9-1024YLLCIGASTLVAMTVS-PALCGI-----------LLANQRLPQEG.................TFVSRWAERLYRPLLNFS
ACRB_ECOLI/1-1030IVSAMALSVLVALILT-PALCAT-----------MLKPIAKGDHGEG.......KKGFFGWFNRMFEKSTHHYTDSVGGI
MDTC_ECOLI/3-1009LSVAIGISLLVSLTLT-PMMCGW-----------MLKASKPREQ............KRLRGFGRMLVALQQGYGKSLKWV
ACRD_ECOLI/1-1027IVAAMVLSVLVAMILT-PALCAT-----------LLKPLKKGEHHG........QKGFFAWFNQMFNRNAERYEKGVAKI
P73998_SYNY3/2-1028IAFSILLSTFLALTLT-PSLCAL-----------LLREGQEPPAFI.........AGFFNWFNRVLDIIKNGYGNVLGKL
O25328_HELPY/1-1011VALAIALSYVVVVTII-PMVSSV-----------VVNPRHS...............RFYVWSEPFFKALESRYTKLLQWV
Q5ZWS7_LEGPH/6-1036VIIALLASMLFALTFV-PAAVAI-----------FLRGHIQEKE..................NRLVHFLSIGYAKVLRRC
Q9I0Y8_PSEAE/3-1040IAISTVISAFNSLTLS-PALAAV-----------LLKGHHEPKDRFSVFLDKLLGSWLFRPFNRFFDRASHGYVGTVNRV

PF02355

SECF_METTH/102-285LIIGLLADILTTWLMN-LGILRW-----------YLEV------------------------------------------
SECF_BORBU/108-297FMVGVIVGTYSSVFIA-SPILLN-----------LYKK------------------------------------------
SECDF_BACSU/540-729LLVGLLTGVYSSLYIA-AQIWLA-----------WKGR------------------------------------------
SECF_STRCO/109-305LFVGLAAGAYSSIFIA-TPLVAD-----------LKEA------------------------------------------
SECF_HAEIN/120-308LLVGIGFGTYSSIFVA-IAIAYD-----------VGLR------------------------------------------
SECF_ECOLI/114-302MLIGVSIGTASSIYVA-SALALK-----------LGMK------------------------------------------
SECF_SYNY3/108-301LIIGFASGVYSSIFMA-TTLWAW-----------WRKW------------------------------------------
SECF_RICPR/110-299VFFGIIAGTYSSIFIS-APILTM-----------FANR------------------------------------------
SECF_HELPY/106-293MLIGTIVGTYSSIFIA-PKVALL-----------LGFD------------------------------------------
SECF_RHOCB/123-311MVWGVFTGTYSSVYVA-KNIVLF-----------IGLD------------------------------------------
SECF_METJA/88-276LILALIADIINTWLLN-AGILKY-----------YITE------------------------------------------
SECF_TREPA/222-411LMVGMVSGVYSTIYIA-GGCIAL-----------ISRG------------------------------------------
Q9ZBS8_STRCO/569-757LLIGVGVGTYSSVFTA-SPLAIE-----------LHNR------------------------------------------
SECF_RHOS4/117-305ITFGVVIGTYSSVYMA-KNIVLY-----------LGVD------------------------------------------
O84454_CHLTR/1200-1393MTVGILLGTLSSLYIA-PPLLLF-----------MVRK------------------------------------------
SECF_MYCLE/183-379QLVGIIVGTYSSIFFA-TPLLVT-----------LRER------------------------------------------
SECF_AQUAE/92-279FVVGVVVGTYSSVFVA-SAFVLD-----------MQKL------------------------------------------

PF02460

O16307_CAEEL/1-766TCVAVAVDFVYQLTFF-VAVLVY-----------EEKRL---------------------------------MKLQKVGE
P91129_CAEEL/47-858TGVAIFFAFIYQITFF-AACLAL-----------AMKHE---------------------------------ASGRNSLF
O44978_CAEEL/31-791ASLALLLDYIFTYTIL-APIVFL-----------CNDPD---------------------------------YKS.....
Q18129_CAEEL/47-926TCVQCFFCYVYQIIFL-GPVLAY-----------AAEME---------------------------------QNGQHVLL
O61894_CAEEL/44-830IALAIMFDWFYQLTFF-AAVMAM-----------GAKRE---------------------------------AAGYHCVF
Q21883_CAEEL/44-838NAVAILFDFIYQITMY-TAILSI-----------CENLE---------------------------------MRKN....
O16530_CAEEL/48-891NALAVITDFVFTITFY-GALMAV-----------VGRYE---------------------------------IEQELKTQ
Q19945_CAEEL/49-901ACVSVAFSYFYQLTFF-SGAMAI-----------MGEVE---------------------------------REKRHCLF
Q09938_CAEEL/52-945TAACMFFTFLYQITFF-AALMVI-----------SAKAQ---------------------------------MSGRNSCM

PF12349

A1CTG5_ASPCL/632-787--------------------------------------------------------------------------------
A1Z6J2_DROME/390-543--------------------------------------------------------------------------------
PTC2_MOUSE/418-570--------------------------------------------------------------------------------
A4S8G2_OSTLU/258-409--------------------------------------------------------------------------------
A5E1Z8_LODEL/460-615--------------------------------------------------------------------------------
A7RI14_NEMVE/240-393--------------------------------------------------------------------------------
A7RNK5_NEMVE/879-1035--------------------------------------------------------------------------------
A7S0G1_NEMVE/641-795--------------------------------------------------------------------------------
NPC1_HUMAN/649-803--------------------------------------------------------------------------------
SCAP_SCHPO/257-410--------------------------------------------------------------------------------
P91346_CAEEL/298-449--------------------------------------------------------------------------------
PTR9_CAEEL/288-439--------------------------------------------------------------------------------
Q16VL3_AEDAE/637-791--------------------------------------------------------------------------------
Q17FP9_AEDAE/355-509--------------------------------------------------------------------------------
Q17N28_AEDAE/360-513--------------------------------------------------------------------------------
Q18968_CAEEL/295-448--------------------------------------------------------------------------------
Q29GK5_DROPS/626-780--------------------------------------------------------------------------------
Q2HB50_CHAGB/263-415--------------------------------------------------------------------------------
A0A0D1C6G9_USTMA/410-564--------------------------------------------------------------------------------
B4Q8Q7_DROSI/652-804--------------------------------------------------------------------------------
F7ANF6_MACMU/1-147--------------------------------------------------------------------------------
G1MH71_AILME/663-814--------------------------------------------------------------------------------
H3CDQ1_TETNG/587-739--------------------------------------------------------------------------------
Q23E28_TETTS/401-549--------------------------------------------------------------------------------
Q7S7Y9_NEUCR/315-463--------------------------------------------------------------------------------

PF03176

MMPL8_MYCTU/74-402--------------------------------------------------------------------------------
MMPL8_MYCTU/676-1049--------------------------------------------------------------------------------
MMPL4_MYCTU/59-388--------------------------------------------------------------------------------
MMPL5_MYCTU/63-393--------------------------------------------------------------------------------
MMPL5_MYCTU/612-950--------------------------------------------------------------------------------
MMPLB_STRCO/48-383--------------------------------------------------------------------------------
MMPL4_MYCLE/57-385--------------------------------------------------------------------------------
MMPL7_MYCTU/74-391--------------------------------------------------------------------------------
MMPLA_MYCTU/29-358--------------------------------------------------------------------------------
MMPL1_MYCTU/52-381--------------------------------------------------------------------------------
MMPL1_MYCTU/600-941--------------------------------------------------------------------------------
MMPL9_MYCTU/58-387--------------------------------------------------------------------------------
MMPL9_MYCTU/606-944--------------------------------------------------------------------------------
YDFJ_BACSU/44-362--------------------------------------------------------------------------------
YDGH_BACSU/39-360--------------------------------------------------------------------------------
MMPL6_MYCTU/28-366--------------------------------------------------------------------------------
MMPL2_MYCTU/54-382--------------------------------------------------------------------------------
MMPL2_MYCTU/601-939--------------------------------------------------------------------------------
MMPLA_MYCLE/55-391--------------------------------------------------------------------------------
Q50086_MYCLR/31-369--------------------------------------------------------------------------------
MMPLC_MYCTU/55-384--------------------------------------------------------------------------------
MMPLC_MYCTU/658-1001--------------------------------------------------------------------------------
MMPLA_STRCO/46-370--------------------------------------------------------------------------------
MMPLA_STRCO/397-682--------------------------------------------------------------------------------
Q9RKC1_STRCO/44-379--------------------------------------------------------------------------------
Q9RL63_STRCO/44-395--------------------------------------------------------------------------------
MMPLD_STRCO/50-373--------------------------------------------------------------------------------
A0A042QG29_MYCTX/43-376--------------------------------------------------------------------------------
A0A042QG29_MYCTX/595-943--------------------------------------------------------------------------------
Q9XCF5_MYCAV/55-384--------------------------------------------------------------------------------
Q9XCF5_MYCAV/604-943--------------------------------------------------------------------------------
Q9XCF6_MYCAV/51-382--------------------------------------------------------------------------------
Q9XCF6_MYCAV/601-939--------------------------------------------------------------------------------
Q9Z577_STRCO/40-368--------------------------------------------------------------------------------

PF00873

CZCA_RALME/5-1037LANTAVVLTFAAVSIVL.CVAIAARLGSEFIPNLNEGDIAIQALRIPGTSLSQSVEMQKTIET.TLKAKFPEIERVF.AR
MEXB_PSEAE/1-1028LKHRAPYLLIYVVIVAG.MIWMFTRIPTAFLPDEDQGVLFAQVQTPPGSSAERTQVVVDSMREYLLEKESSSVSSVF.TV
MDTB_ECOLI/12-1023LNHPWLTLSVALSTLLL.SVLLWVFIPKGFFPVQDNGIIQGTLQAPQSSSFANMAQRQRQVAD.VIL.QDPAVQSLT.SF
ACRF_ECOLI/1-1029LGSTGRYLLIYALIVAG.MVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQKVLDQVTDYYLKNEKANVESVF.TV
P74461_SYNY3/10-1047IRHRLVAVASIFIVFGGSSLWMIGQIPQEILPRINTGQASMFAQFPPGTPLEENQRLMAIVDD.ILI.NQPETEYAFTTV
O25622_HELPY/6-1014VHNPKKVILGAFVFLIA.SLSLFPFVGKNFMPVLDEGDVVLSVETTPSISLDQSRDLMLNIES.AIKKHVKEVKSIV.AR
MDTF_ECOLI/1-1028LRCTGRYMVVYLLICAG.MAVLFLRTPTSFLPEEDQGVFMTTAQLPSGATMVNTTKVLQQVTDYYLTKEKDNVQSVF.TV
Q55935_SYNY3/9-1024LRAPQVILSIALIAVIA.SVSLVPSLGRVFLPEFREKSMVNSMVLFPGVSLDMTNRAGMALFN.NLK.DNPLYEWVQ.IR
ACRB_ECOLI/1-1030LRSTGRYLVLYLIIVVG.MAYLFVRLPSSFLPDEDQGVFMTMVQLPAGATQERTQKVLNEVTHYYLTKEKNNVESVF.AV
MDTC_ECOLI/3-1009LNHTRLVGVVLLGTIAL.NIWLYISIPKTFFPEQDTGVLMGGIQADQSISFQAMRGKLQDFMK.IIR.DDPAVDNVT.GF
ACRD_ECOLI/1-1027LHRSLRWIVIYVLLLGG.MVFLFLRLPTSFLPLEDRGMFTTSVQLPSGSTQQQTLKVVEQIEKYYFTHEKDNIMSVF.AT
P73998_SYNY3/2-1028VNLRAWVIGVFVLLLGA.TAWLYVTVPTAFLPEEDQGYFITIIQAPQGVSLQYTSRVMAQVEK.ELL.AVPEVTATF.AV
O25328_HELPY/1-1011LNHKIIISIAVVLVFVG.SLFVASKIGMEFMLKEDRGRFLVWLKAKPGVSIDYMTQKSKIFQK.AIE.KHAEVEFTT.LQ
Q5ZWS7_LEGPH/6-1036FHARRQVIGAAVVLVII.SFMLAFRLGGEFIPSLDEGDIAMHAMRIPGTSLTQAIAMQDLVEK.RVR.QFPEVKRVF.AK
Q9I0Y8_PSEAE/3-1040LRGSSIALLVYGGLMVL.TYFGFSSTPTGFVPQQDKQYLVAFAQLPDAASLDRTEAVIKQMSE.IAL.AQPGVADSV.AF

PF02355

SECF_METTH/102-285--------------------------------------------------------------------------------
SECF_BORBU/108-297--------------------------------------------------------------------------------
SECDF_BACSU/540-729--------------------------------------------------------------------------------
SECF_STRCO/109-305--------------------------------------------------------------------------------
SECF_HAEIN/120-308--------------------------------------------------------------------------------
SECF_ECOLI/114-302--------------------------------------------------------------------------------
SECF_SYNY3/108-301--------------------------------------------------------------------------------
SECF_RICPR/110-299--------------------------------------------------------------------------------
SECF_HELPY/106-293--------------------------------------------------------------------------------
SECF_RHOCB/123-311--------------------------------------------------------------------------------
SECF_METJA/88-276--------------------------------------------------------------------------------
SECF_TREPA/222-411--------------------------------------------------------------------------------
Q9ZBS8_STRCO/569-757--------------------------------------------------------------------------------
SECF_RHOS4/117-305--------------------------------------------------------------------------------
O84454_CHLTR/1200-1393--------------------------------------------------------------------------------
SECF_MYCLE/183-379--------------------------------------------------------------------------------
SECF_AQUAE/92-279--------------------------------------------------------------------------------

PF02460

O16307_CAEEL/1-766EKK....IEAAM..ERRP.............KQVLSIQNSIR......................................
P91129_CAEEL/47-858LIEA...VSAEK..KTSLS...........TFQRLFNLGSVP......................................
O44978_CAEEL/31-791..................................IANET.EP......................................
Q18129_CAEEL/47-926IRKA...VDPDK..TESPVKLWLLSGSVNRQDQEARRRNSRKVAPVEKEGEKKSKF.................GEVVEKL
O61894_CAEEL/44-830VW..............................KRCDREEIAK......................................
Q21883_CAEEL/44-838.........AT....K.................RKDSGLSFK......................................
O16530_CAEEL/48-891KP.......LPE..SESP..............SETSSTGSMR......................................
Q19945_CAEEL/49-901FYRTFQLVDISKMNEEADS...........KLQQIKSRSASPAPFNYLSSSNSSFSSDSDSFS....SKKTIPAEFAWKE
Q09938_CAEEL/52-945PC.......IT.......AG..........DIYTIEDGSLQPNLKKKKSKSRKDAKAEKEKKDEAKNDKNMEIEENAENA

PF12349

A1CTG5_ASPCL/632-787--------------------------------------------------------------------------------
A1Z6J2_DROME/390-543--------------------------------------------------------------------------------
PTC2_MOUSE/418-570--------------------------------------------------------------------------------
A4S8G2_OSTLU/258-409--------------------------------------------------------------------------------
A5E1Z8_LODEL/460-615--------------------------------------------------------------------------------
A7RI14_NEMVE/240-393--------------------------------------------------------------------------------
A7RNK5_NEMVE/879-1035--------------------------------------------------------------------------------
A7S0G1_NEMVE/641-795--------------------------------------------------------------------------------
NPC1_HUMAN/649-803--------------------------------------------------------------------------------
SCAP_SCHPO/257-410--------------------------------------------------------------------------------
P91346_CAEEL/298-449--------------------------------------------------------------------------------
PTR9_CAEEL/288-439--------------------------------------------------------------------------------
Q16VL3_AEDAE/637-791--------------------------------------------------------------------------------
Q17FP9_AEDAE/355-509--------------------------------------------------------------------------------
Q17N28_AEDAE/360-513--------------------------------------------------------------------------------
Q18968_CAEEL/295-448--------------------------------------------------------------------------------
Q29GK5_DROPS/626-780--------------------------------------------------------------------------------
Q2HB50_CHAGB/263-415--------------------------------------------------------------------------------
A0A0D1C6G9_USTMA/410-564--------------------------------------------------------------------------------
B4Q8Q7_DROSI/652-804--------------------------------------------------------------------------------
F7ANF6_MACMU/1-147--------------------------------------------------------------------------------
G1MH71_AILME/663-814--------------------------------------------------------------------------------
H3CDQ1_TETNG/587-739--------------------------------------------------------------------------------
Q23E28_TETTS/401-549--------------------------------------------------------------------------------
Q7S7Y9_NEUCR/315-463--------------------------------------------------------------------------------

PF03176

MMPL8_MYCTU/74-402----------------------------------------------------------.........APRRDLTR.....
MMPL8_MYCTU/676-1049----------------------------------------------------------......................
MMPL4_MYCTU/59-388----------------------------------------------------------.........DPKRLLKV.....
MMPL5_MYCTU/63-393----------------------------------------------------------.........EPKRMARV.....
MMPL5_MYCTU/612-950----------------------------------------------------------......................
MMPLB_STRCO/48-383----------------------------------------------------------.........GVDKAAERSRGA.
MMPL4_MYCLE/57-385----------------------------------------------------------.........EPKRLIKV.....
MMPL7_MYCTU/74-391----------------------------------------------------------.........AP...TTG.....
MMPLA_MYCTU/29-358----------------------------------------------------------.........APRGERMA.....
MMPL1_MYCTU/52-381----------------------------------------------------------.........DPKRATTK.....
MMPL1_MYCTU/600-941----------------------------------------------------------......................
MMPL9_MYCTU/58-387----------------------------------------------------------.........DPKRRLKT.....
MMPL9_MYCTU/606-944----------------------------------------------------------......................
YDFJ_BACSU/44-362----------------------------------------------------------.........SNKKIEKQSTET.
YDGH_BACSU/39-360----------------------------------------------------------.........WPSKKVLSHSD..
MMPL6_MYCTU/28-366----------------------------------------------------------......................
MMPL2_MYCTU/54-382----------------------------------------------------------.........DPKRRMNT.....
MMPL2_MYCTU/601-939----------------------------------------------------------......................
MMPLA_MYCLE/55-391----------------------------------------------------------.........APRRDRAG.....
Q50086_MYCLR/31-369----------------------------------------------------------......................
MMPLC_MYCTU/55-384----------------------------------------------------------.........KPRRDLTS.....
MMPLC_MYCTU/658-1001----------------------------------------------------------......................
MMPLA_STRCO/46-370----------------------------------------------------------.........RPKHGTEPDVTR.
MMPLA_STRCO/397-682----------------------------------------------------------......................
Q9RKC1_STRCO/44-379----------------------------------------------------------..AKGKRLGRSRKGEPKPDRPA
Q9RL63_STRCO/44-395----------------------------------------------------------RFRKGRSTPPARRLRGGPGRGA
MMPLD_STRCO/50-373----------------------------------------------------------.........KPVRTGDPEAGH.
A0A042QG29_MYCTX/43-376----------------------------------------------------------.........PPQHKRIQ.....
A0A042QG29_MYCTX/595-943----------------------------------------------------------......................
Q9XCF5_MYCAV/55-384----------------------------------------------------------.........EPRRAVSA.....
Q9XCF5_MYCAV/604-943----------------------------------------------------------......................
Q9XCF6_MYCAV/51-382----------------------------------------------------------.........DPKRAIGF.....
Q9XCF6_MYCAV/601-939----------------------------------------------------------......................
Q9Z577_STRCO/40-368----------------------------------------------------------.........RERRRLAEHGPEP

PF00873

CZCA_RALME/5-1037TGTAEIASDLMPPNISDGYIMLKPEKDWPEPKK.THAELLSAIQEEAGKIPGNNYEF.SQPIQLRF..NELISGVRSDVA
MEXB_PSEAE/1-1028TGFNF.AG..RGQSSGMAFIMLKPWEERPGGEN.SVFELAKRAQMHFFSFKDAMVFA.FAPPSVLE..LGNATGFDLFLQ
MDTB_ECOLI/12-1023VGV...DGTNPSLNSARLQINLKPLDER...DD.RVQKVIARLQTAVDKVPGVDLFL.QPTQDLTI....DTQVSRTQYQ
ACRF_ECOLI/1-1029NGFSF.SG..QAQNAGMAFVSLKPWEERNGDEN.SAEAVIHRAKMELGKIRDGFVIP.FNMPAIVE..LGTATGFDFELI
P74461_SYNY3/10-1047GGFLFGSNVNANALRSSSTITLKPNT........DVEAFTERVTAELEALNLVDIRLRMAPGQLRGLILSNSPLRNVDVD
O25622_HELPY/6-1014TGSDELGLDLGGLNQTDTFISFIPKKEW..SVK.TKDELLEKIMDSLKDFKGINFSF.TQPIEMRI..SEMLTGVRGDLA
MDTF_ECOLI/1-1028GGFGF.SG..QGQNNGLAFISLKPWSERVGEEN.SVTAIIQRAMIALSSINKAVVFP.FNLPAVAE..LGTASGFDMELL
Q55935_SYNY3/9-1024AGRAPGDADGAGVSMAHVDVELSDEALK......DREASVKELRKAFNQLPGVASNM.GGFISHRM..DEVLSGVRSAIA
ACRB_ECOLI/1-1030NGFGF.AG..RGQNTGIAFVSLKDWADRPGEEN.KVEAITMRATRAFSQIKDAMVFA.FNLPAIVE..LGTATGFDFELI
MDTC_ECOLI/3-1009TGG.......SRVNSGMMFITLKPRDER...SE.TAQQIIDRLRVKLAKEPGANLFL.MAVQDIRV....GGRQSNASYQ
ACRD_ECOLI/1-1027VGSGP.GG..NGQNVARMFIRLKDWSERDSKTG.TSFAIIERATKAFNQIKEARVIA.SSPPAISG..LGSSAGFDMELQ
P73998_SYNY3/2-1028GGFSF.SG..NSPNQGIIFTRLKPWGERTAPNQ.SVQAIIGQMFGKFSQIPEANIIP.INPPPIRG..LGQFGGFDFQLQ
O25328_HELPY/1-1011VG....YGTTQNPFKAKIFVQLKPLKERKKEHQLGQFELMSVLRKELRSLPEAK..G.LDTINLSEVTLIGGGGDSSPFQ
Q5ZWS7_LEGPH/6-1036LGTAEVATDPMPPNVADTFIMLKPRNEWPNPKK.SKQQLVQEIEQAVKQIPGNNYEF.TQPIQMRF..NELISGVRSDVA
Q9I0Y8_PSEAE/3-1040PGLSI.NGFTNSPNSGIVFTPLKPFDERKDPSQ.SAGAIAAALNAKYADIQDAYIAI.FPPPPVQG..LGTIGGFRLQIE

PF02355

SECF_METTH/102-285--------------------------------------------------------------------------------
SECF_BORBU/108-297--------------------------------------------------------------------------------
SECDF_BACSU/540-729--------------------------------------------------------------------------------
SECF_STRCO/109-305--------------------------------------------------------------------------------
SECF_HAEIN/120-308--------------------------------------------------------------------------------
SECF_ECOLI/114-302--------------------------------------------------------------------------------
SECF_SYNY3/108-301--------------------------------------------------------------------------------
SECF_RICPR/110-299--------------------------------------------------------------------------------
SECF_HELPY/106-293--------------------------------------------------------------------------------
SECF_RHOCB/123-311--------------------------------------------------------------------------------
SECF_METJA/88-276--------------------------------------------------------------------------------
SECF_TREPA/222-411--------------------------------------------------------------------------------
Q9ZBS8_STRCO/569-757--------------------------------------------------------------------------------
SECF_RHOS4/117-305--------------------------------------------------------------------------------
O84454_CHLTR/1200-1393--------------------------------------------------------------------------------
SECF_MYCLE/183-379--------------------------------------------------------------------------------
SECF_AQUAE/92-279--------------------------------------------------------------------------------

PF02460

O16307_CAEEL/1-766........STAGAHPPP..ANP.....NGIVSRYCRFLKDWKTRLCLLLVLCGYWTASYYGCKTMEIKMDTTNLIMNDSP
P91129_CAEEL/47-858.......DHSASHDVKQ.PLTS.....RFFGEWYAPVLMHPVVRGIAMVWFVIYLLGASYGCSRIKEGLEPVNLLVEDSY
O44978_CAEEL/31-791.............KISR....A.....DTWLSKYSSFVCSVKGRVACIMVLLGMYALTTYGVVTMKTTFEPAKAFPSNSK
Q18129_CAEEL/47-926EHTLEKHDDDPGHNSEE.TLVS.....KVFREIIGPFILQKSTQVCALLLYLVYISLAIGGCLNIKEGLDPKLLVRESFY
O61894_CAEEL/44-830.........AKNENAIS..PTR.....YFFENIFAPFICRPSVRFCMLNLYVVYIAIAFYGCSQLTPNLTPSQLVVDDSP
Q21883_CAEEL/44-838..............NEQ....F.....TVMLDSYCDWVANAYTHLLVLFCFIVYIFVSIRGALNINIILSPDKLVIGDSP
O16530_CAEEL/48-891...........SSELDD..CKF.....RRMIANVCKFLTNTWVCSVVLGLLAVYWYICIVGTVNIKSELSPNKLFLAESN
Q19945_CAEEL/49-901QQSPNSSLSKKSKDREEKDRIV.....HFIGKIYGPFILSNSVRIFSGLIFVVYLAIAMYGCYNFREGLNPGNLVTNDHY
Q09938_CAEEL/52-945EKSSYDSSPDPSQIHIP..VKSRGAMGHFFRDYYVPWLLNWKTKLFMFVTFIIYLGISVYGICVMEQGLDYDKLLLHSDP

PF12349

A1CTG5_ASPCL/632-787---------------.ESLRADCMPCVTV---------------------------------------------------
A1Z6J2_DROME/390-543---------------EYTAEAKHLPKMLL---------------------------------------------------
PTC2_MOUSE/418-570---------------.HRQRLDVLCCFSS---------------------------------------------------
A4S8G2_OSTLU/258-409---------------.SENKADCFFCLDC---------------------------------------------------
A5E1Z8_LODEL/460-615---------------.ESNRVDCAPWITI---------------------------------------------------
A7RI14_NEMVE/240-393---------------EGILLRQRGRLHSS---------------------------------------------------
A7RNK5_NEMVE/879-1035---------------DRKRDGCCCCCIVL---------------------------------------------------
A7S0G1_NEMVE/641-795---------------.ETNRWDIMCCVKQ---------------------------------------------------
NPC1_HUMAN/649-803---------------.EKNRLDIFCCVRG---------------------------------------------------
SCAP_SCHPO/257-410---------------ELQDFLDSNSSNRN---------------------------------------------------
P91346_CAEEL/298-449---------------.EQGLHSIWLRPAV---------------------------------------------------
PTR9_CAEEL/288-439---------------.VSGKHPVFCCYEI---------------------------------------------------
Q16VL3_AEDAE/637-791---------------.ASGRLDLFCCVKS---------------------------------------------------
Q17FP9_AEDAE/355-509---------------.ADNRYDVLFFLRG---------------------------------------------------
Q17N28_AEDAE/360-513---------------EYSAEVRQLPKMLY---------------------------------------------------
Q18968_CAEEL/295-448---------------GLEEKRKFAEILLY---------------------------------------------------
Q29GK5_DROPS/626-780---------------.LDGRLDMLCCVQT---------------------------------------------------
Q2HB50_CHAGB/263-415---------------ELCE.LEKASLKRA---------------------------------------------------
A0A0D1C6G9_USTMA/410-564---------------ELADLLTQGTRLSR---------------------------------------------------
B4Q8Q7_DROSI/652-804---------------.EENRMDICCFIK.---------------------------------------------------
F7ANF6_MACMU/1-147---------------ELADLNK.......---------------------------------------------------
G1MH71_AILME/663-814---------------.EASRLDVCCCV..---------------------------------------------------
H3CDQ1_TETNG/587-739---------------.DSNRCELLCCIK.---------------------------------------------------
Q23E28_TETTS/401-549---------------.LKGICDVFVCIR.---------------------------------------------------
Q7S7Y9_NEUCR/315-463---------------.ELYELEKASL...---------------------------------------------------

PF03176

MMPL8_MYCTU/74-402...........RFW.RSSGVHIVRRPKTH---------------------------------------------------
MMPL8_MYCTU/676-1049...........NWWLPSSWRPATWWPLGR---------------------------------------------------
MMPL4_MYCTU/59-388...........RGW.RRVGTVVVRWPLPV---------------------------------------------------
MMPL5_MYCTU/63-393...........RGW.RKVGAAIVRWPGPI---------------------------------------------------
MMPL5_MYCTU/612-950...........FWW.PQV...VRQRPIPQ---------------------------------------------------
MMPLB_STRCO/48-383...........GIW.HRIAALVARAPVKV---------------------------------------------------
MMPL4_MYCLE/57-385...........RGW.RRIGTVVVRWPLPI---------------------------------------------------
MMPL7_MYCTU/74-391...........AGW...TGRLSLPVSSAS---------------------------------------------------
MMPLA_MYCTU/29-358...........TFW.RRAGTRIVRRPKAY---------------------------------------------------
MMPL1_MYCTU/52-381...........RRW.RRIGTVVVRWPGPV---------------------------------------------------
MMPL1_MYCTU/600-941...........FWW.PRRVDRLARQPQVL---------------------------------------------------
MMPL9_MYCTU/58-387...........RGW.RRVGTAVVRWPGPI---------------------------------------------------
MMPL9_MYCTU/606-944...........FWW.PNM...IHSRPTVP---------------------------------------------------
YDFJ_BACSU/44-362...........NVW....GRFVTKNPIML---------------------------------------------------
YDGH_BACSU/39-360..........NKLW.AFLGRHSVARPFLF---------------------------------------------------
MMPL6_MYCTU/28-366...........FWW.PQR...VRPRPASR---------------------------------------------------
MMPL2_MYCTU/54-382...........RRW.RRVGTAIVRWPGPV---------------------------------------------------
MMPL2_MYCTU/601-939...........FWW.PLR...VRPRPASQ---------------------------------------------------
MMPLA_MYCLE/55-391...........AFW.RRTGVRIVRRPVAY---------------------------------------------------
Q50086_MYCLR/31-369...........FWW.PQQ...GRTRPLLT---------------------------------------------------
MMPLC_MYCTU/55-384...........RMW.RRSGVRIVRRSTIH---------------------------------------------------
MMPLC_MYCTU/658-1001...........NWW.PSELGRDPSTPPTK---------------------------------------------------
MMPLA_STRCO/46-370...........GLW.SRIARLVSGRPRAV---------------------------------------------------
MMPLA_STRCO/397-682...........MWW...........PHPL---------------------------------------------------
Q9RKC1_STRCO/44-379GQPKANLG...TRW....ASFVVRRPLAV---------------------------------------------------
Q9RL63_STRCO/44-395ARRTREAGAWSVRW....ARFVQRRPVPV---------------------------------------------------
MMPLD_STRCO/50-373...........RLW.HRVAALVDRAPRRI---------------------------------------------------
A0A042QG29_MYCTX/43-376...........RQF.RRLGTHVARWPAPI---------------------------------------------------
A0A042QG29_MYCTX/595-943...........LWW.PRRSVSNRQVPEPS---------------------------------------------------
Q9XCF5_MYCAV/55-384...........RRW.RRIGTAIVRWPAPI---------------------------------------------------
Q9XCF5_MYCAV/604-943...........FWW.PQL...VRPRPAST---------------------------------------------------
Q9XCF6_MYCAV/51-382...........GRW.RRIGTAIVRWPTPI---------------------------------------------------
Q9XCF6_MYCAV/601-939...........FWW.PQL...VRRRPASQ---------------------------------------------------
Q9Z577_STRCO/40-368EVPTGFA....ARW....SAFVERRPKLL---------------------------------------------------

PF00873

CZCA_RALME/5-1037VKIFGDDNNVLSETAKKVSAVLQGIPG.A..-..QEVKVEQTTGLPMLTVKIDREKAARYGLNMSDVQDAVATGVGG.RD
MEXB_PSEAE/1-1028D.QAGVGHEVLLQARNKFLMLAAQNPA.L..-..QRVRPNGMSDEPQYKLEIDDEKASALGVSLADINSTVSIAWGS.SY
MDTB_ECOLI/12-1023FTLQATSLDALSTWVPQLMEKLQQLPQ.L..-..SDVSSDWQDKGLVAYVNVDRDSASRLGISMADVDNALYNAFGQ.RL
ACRF_ECOLI/1-1029D.QAGLGHDALTQARNQLLGMAAQHPASL..-..VSVRPNGLEDTAQFKLEVDQEKAQALGVSLSDINQTISTALGG.TY
P74461_SYNY3/10-1047VVLQGNDADVLDEAGRAVLAELGEKVT.L..-..ARFRPDADPRQPEVQIRPDWQRATELGLTTQAIGQTVQTALDG.AV
O25622_HELPY/6-1014VKIFGDGISELNELSFQIAQALKGIKG.S..-..SEVLTTLNEGVNYLYVTPNKESMADVGITSDEFSKFLKSALEG.LV
MDTF_ECOLI/1-1028D.NGNLGHEKLTQARNELLSLAAQSPNQV..-..TGVRPNGLEDTPMFKVNVNAAKAEAMGVALSDINQTISTAFGS.SY
Q55935_SYNY3/9-1024VKIFGPDLKELRAIGEQVQEAMKTVPG.I..-..VDLQLEPQLPIRQVQIHYDRAAAAQYGLRMADISAVVETALNG.RI
ACRB_ECOLI/1-1030D.QAGLGHEKLTQARNQLLAEAAKHPDML..-..TSVRPNGLEDTPQFKIDIDQEKAQALGVSINDINTTLGAAWGG.SY
MDTC_ECOLI/3-1009YTLLSDDLAALREWEPKIRKKLATLPE.L..-..ADVNSDQQDNGAEMNLVYDRDTMARLGIDVQAANSLLNNAFGQ.RQ
ACRD_ECOLI/1-1027D.HAGAGHDALMAARNQLLALAAENPE.L..-..TRVRHNGLDDSPQLQIDIDQRKAQALGVAIDDINDTLQTAWGS.SY
P73998_SYNY3/2-1028DLRVNSELDTMVGTMGEILGAANQNPA.L..-..TRVFSTFQANNPQLIVNVNRNKAKSLGVPVDQIFQTMETALGS.SY
O25328_HELPY/1-1011TFVFSHSQEAVDKSVENLKKFLLESPE.LKG-KVESYHTSTSESQPQLQLKILRQNANKYGVSAQTIGSVVSSAFSGTSQ
Q5ZWS7_LEGPH/6-1036VKVFGDDMPTLLKTADAISAELKKVPG.A..-..SDVKVEQVSGLPLLTIEINRDALARYGLQIGNVQDAIVIAAGG.KK
Q9I0Y8_PSEAE/3-1040D.RGNQGYEELFKQTQNIITKARALPE.LE.-.PSSVFSSYQVNVPQIDADIDREKAKTHGVAISDIFDTLQVYLGS.LY

PF02355

SECF_METTH/102-285--------------------------------------------------------------------------------
SECF_BORBU/108-297--------------------------------------------------------------------------------
SECDF_BACSU/540-729--------------------------------------------------------------------------------
SECF_STRCO/109-305--------------------------------------------------------------------------------
SECF_HAEIN/120-308--------------------------------------------------------------------------------
SECF_ECOLI/114-302--------------------------------------------------------------------------------
SECF_SYNY3/108-301--------------------------------------------------------------------------------
SECF_RICPR/110-299--------------------------------------------------------------------------------
SECF_HELPY/106-293--------------------------------------------------------------------------------
SECF_RHOCB/123-311--------------------------------------------------------------------------------
SECF_METJA/88-276--------------------------------------------------------------------------------
SECF_TREPA/222-411--------------------------------------------------------------------------------
Q9ZBS8_STRCO/569-757--------------------------------------------------------------------------------
SECF_RHOS4/117-305--------------------------------------------------------------------------------
O84454_CHLTR/1200-1393--------------------------------------------------------------------------------
SECF_MYCLE/183-379--------------------------------------------------------------------------------
SECF_AQUAE/92-279--------------------------------------------------------------------------------

PF02460

O16307_CAEEL/1-766LNHIAWIYERFLWSEGQLVMVFVNNPPDLTK.SENLHEVLELVNRFETLPYSMGKNSTSIWLRSFL..Y........QSS
P91129_CAEEL/47-858AIPHYRLLEKYFWKYGQQVQIVINNAPDLRN.HTSRDRVHAMVLDFATSKHAIGMESVQFWLFEMER.YYQ......KEL
O44978_CAEEL/31-791LVDSLSNI.KPVFNRYFPITVIVNNPPNIEI.KAEYDSFNNMMDRLEHVPGIRGDNRSLIFLPQYVNFDKT.....MNIL
Q18129_CAEEL/47-926LSKFYEIIDETFWREGLQMQVVVNNPPDLFT.PETRKGFDEMMAEFENTQYTMHPNATMIWLRAYEHHLET......EVH
O61894_CAEEL/44-830LVPYLNLAEKKIWAEGLIGRIYVNNAPDFSKNPEMVDRMLQMVNELESTPYSMGPNSTNFWLNEFN..NYR......QFF
Q21883_CAEEL/44-838LLQVNYLRDQFVLPNYTTVNIFVQNPGNLTI.QSNLDYMNSLFDSFESYPECLGKKFSHYFVRDYESFRESS...LEEME
O16530_CAEEL/48-891IVEIFKQRKSHIIPYYSACWVLVENPGDINN.PNQRAKLEELIESFEALPSANGRYSTKFWLRDYEDFLKQSEEIDLPME
Q19945_CAEEL/49-901IAKYFSDI.KHFWRIGAQLHVAVLNPPNLTI.SENRNELLKVVSAFENTQYTLGREGTVFFLLEYLNYL..S...ELNAE
Q09938_CAEEL/52-945LVEALK.REIELFHGGDQIEIAIQNCPNITI.AESRDRIELVAQEFENISYSLGGKGTSFWMREYKK.Y..S...NLTGS

PF12349

A1CTG5_ASPCL/632-787--------------------------------------------------------------------------------
A1Z6J2_DROME/390-543--------------------------------------------------------------------------------
PTC2_MOUSE/418-570--------------------------------------------------------------------------------
A4S8G2_OSTLU/258-409--------------------------------------------------------------------------------
A5E1Z8_LODEL/460-615--------------------------------------------------------------------------------
A7RI14_NEMVE/240-393--------------------------------------------------------------------------------
A7RNK5_NEMVE/879-1035--------------------------------------------------------------------------------
A7S0G1_NEMVE/641-795--------------------------------------------------------------------------------
NPC1_HUMAN/649-803--------------------------------------------------------------------------------
SCAP_SCHPO/257-410--------------------------------------------------------------------------------
P91346_CAEEL/298-449--------------------------------------------------------------------------------
PTR9_CAEEL/288-439--------------------------------------------------------------------------------
Q16VL3_AEDAE/637-791--------------------------------------------------------------------------------
Q17FP9_AEDAE/355-509--------------------------------------------------------------------------------
Q17N28_AEDAE/360-513--------------------------------------------------------------------------------
Q18968_CAEEL/295-448--------------------------------------------------------------------------------
Q29GK5_DROPS/626-780--------------------------------------------------------------------------------
Q2HB50_CHAGB/263-415--------------------------------------------------------------------------------
A0A0D1C6G9_USTMA/410-564--------------------------------------------------------------------------------
B4Q8Q7_DROSI/652-804--------------------------------------------------------------------------------
F7ANF6_MACMU/1-147--------------------------------------------------------------------------------
G1MH71_AILME/663-814--------------------------------------------------------------------------------
H3CDQ1_TETNG/587-739--------------------------------------------------------------------------------
Q23E28_TETTS/401-549--------------------------------------------------------------------------------
Q7S7Y9_NEUCR/315-463--------------------------------------------------------------------------------

PF03176

MMPL8_MYCTU/74-402--------------------------------------------------------------------------------
MMPL8_MYCTU/676-1049--------------------------------------------------------------------------------
MMPL4_MYCTU/59-388--------------------------------------------------------------------------------
MMPL5_MYCTU/63-393--------------------------------------------------------------------------------
MMPL5_MYCTU/612-950--------------------------------------------------------------------------------
MMPLB_STRCO/48-383--------------------------------------------------------------------------------
MMPL4_MYCLE/57-385--------------------------------------------------------------------------------
MMPL7_MYCTU/74-391--------------------------------------------------------------------------------
MMPLA_MYCTU/29-358--------------------------------------------------------------------------------
MMPL1_MYCTU/52-381--------------------------------------------------------------------------------
MMPL1_MYCTU/600-941--------------------------------------------------------------------------------
MMPL9_MYCTU/58-387--------------------------------------------------------------------------------
MMPL9_MYCTU/606-944--------------------------------------------------------------------------------
YDFJ_BACSU/44-362--------------------------------------------------------------------------------
YDGH_BACSU/39-360--------------------------------------------------------------------------------
MMPL6_MYCTU/28-366--------------------------------------------------------------------------------
MMPL2_MYCTU/54-382--------------------------------------------------------------------------------
MMPL2_MYCTU/601-939--------------------------------------------------------------------------------
MMPLA_MYCLE/55-391--------------------------------------------------------------------------------
Q50086_MYCLR/31-369--------------------------------------------------------------------------------
MMPLC_MYCTU/55-384--------------------------------------------------------------------------------
MMPLC_MYCTU/658-1001--------------------------------------------------------------------------------
MMPLA_STRCO/46-370--------------------------------------------------------------------------------
MMPLA_STRCO/397-682--------------------------------------------------------------------------------
Q9RKC1_STRCO/44-379--------------------------------------------------------------------------------
Q9RL63_STRCO/44-395--------------------------------------------------------------------------------
MMPLD_STRCO/50-373--------------------------------------------------------------------------------
A0A042QG29_MYCTX/43-376--------------------------------------------------------------------------------
A0A042QG29_MYCTX/595-943--------------------------------------------------------------------------------
Q9XCF5_MYCAV/55-384--------------------------------------------------------------------------------
Q9XCF5_MYCAV/604-943--------------------------------------------------------------------------------
Q9XCF6_MYCAV/51-382--------------------------------------------------------------------------------
Q9XCF6_MYCAV/601-939--------------------------------------------------------------------------------
Q9Z577_STRCO/40-368--------------------------------------------------------------------------------

PF00873

CZCA_RALME/5-1037SGTFFQGDRRFDIVVRLPEAVRGEVEALRRLPIPLPKGVDARTTFIPLSEVATLEMAPGPNQISRENGKRRIVISANV..
MEXB_PSEAE/1-1028VNDFIDRGRVKRVYLQGRPDARMNPDDLSKWYVRNDKGE.....MVPFNAFATGKWEYGSPKLERYNGVPAMEILGEP..
MDTB_ECOLI/12-1023ISTIYTQANQYRVVLEHNTENTPGLAALDTIRLTSSDGG.....VVPLSSIAKIEQRFAPLSINHLDQFPVTTISFNV..
ACRF_ECOLI/1-1029VNDFIDRGRVKKLYVQADAKFRMLPEDVDKLYVRSANGE.....MVPFSAFTTSHWVYGSPRLERYNGLPSMEIQGEA..
P74461_SYNY3/10-1047PTQLQRENRLVDVRVKLDNDLLSGPGDLAQIPLFIDGDR.....PIRLGDVATIDQGRAPGEIQRINQRPVFLIAGTL..
O25622_HELPY/6-1014VDVIPTGISRTPVMIRQESDFASSITKIKSLALTSKYGV.....LVPITSIAKIEEVDGPVSVVRENSMRMSVVRSNV..
MDTF_ECOLI/1-1028VNDFLNQGRVKKVYVQAGTPFRMLPDNINQWYVRNASGT.....MAPLSAYSSTEWTYGSPRLERYNGIPSMEILGEA..
Q55935_SYNY3/9-1024VSQVPEDQQLVNVVVMLPETERNSLDAMGAIPISTPTGQ.....MITLGDVAKIDYGMGANVVNREDVSRLIVVSANV..
ACRB_ECOLI/1-1030VNDFIDRGRVKKVYVMSEAKYRMLPDDIGDWYVRAADGQ.....MVPFSAFSSSRWEYGSPRLERYNGLPSMEILGQA..
MDTC_ECOLI/3-1009ISTIYQPMNQYKVVMEVDPRYTQDISALEKMFVINNEGK.....AIPLSYFAKWQPANAPLSVNHQGLSAASTISFNL..
ACRD_ECOLI/1-1027VNDFMDRGRVKKVYVQAAAPYRMLPDDINLWYVRNKDGG.....MVPFSAFATSRWETGSPRLERYNGYSAVEIVGEA..
P73998_SYNY3/2-1028VNDFVLQGRTYRVYLQADEQFRSSPEDINSLYVRSESGT.....MIPMANLVTVTQGVGAPIITHYNLFRSIAITGSA..
O25328_HELPY/1-1011ASVFKEDGKEYDMIIRVPDDKRVSVEDIKRLQVRNKYDK.....LMFLDALVEITETKSPSSISRYNRQRSVTVLAEPNR
Q5ZWS7_LEGPH/6-1036GGELFEGDKRFDLIVRLPEALRTSPTVLRQVFIPLPLAKDGERHFIPLSEVAKMVRSESPNQISREVGKRRVVVTANV..
Q9I0Y8_PSEAE/3-1040ANDFNRFGRTYQVNVQAEQQFRLEPEQIGQLKVRNNLGE.....MVPLASFIKVSDTSGPDRVMHYNGFITAELNGAP..

PF02355

SECF_METTH/102-285--------------------------------------------------------------------------------
SECF_BORBU/108-297--------------------------------------------------------------------------------
SECDF_BACSU/540-729--------------------------------------------------------------------------------
SECF_STRCO/109-305--------------------------------------------------------------------------------
SECF_HAEIN/120-308--------------------------------------------------------------------------------
SECF_ECOLI/114-302--------------------------------------------------------------------------------
SECF_SYNY3/108-301--------------------------------------------------------------------------------
SECF_RICPR/110-299--------------------------------------------------------------------------------
SECF_HELPY/106-293--------------------------------------------------------------------------------
SECF_RHOCB/123-311--------------------------------------------------------------------------------
SECF_METJA/88-276--------------------------------------------------------------------------------
SECF_TREPA/222-411--------------------------------------------------------------------------------
Q9ZBS8_STRCO/569-757--------------------------------------------------------------------------------
SECF_RHOS4/117-305--------------------------------------------------------------------------------
O84454_CHLTR/1200-1393--------------------------------------------------------------------------------
SECF_MYCLE/183-379--------------------------------------------------------------------------------
SECF_AQUAE/92-279--------------------------------------------------------------------------------

PF02460

O16307_CAEEL/1-766LYHNNK.................GF.NGLLQEWLEDSEGGGA.RWNDMLRLK.KDENGTILGIDKFMFATACAMGDDANW
P91129_CAEEL/47-858EVQIID.................SS.FYGLLHHFLASKTNNP.LAEDIYWGP.MPDDDNGTMVKSFRFILG..MKDLVTT
O44978_CAEEL/31-791STLVGEK................YRPSYDNLPTWMDAIGNPP.LVKYHMGD......DNKTIVTAFRLTLL..GKGMSEW
Q18129_CAEEL/47-926ELNIEKPNS............TVEW.YTRCRDWLIVAGGRRL.WQMDMVWA..NTTFEETPRITAFRFQLG..LRNYRTP
O61894_CAEEL/44-830FQEDAK....................FYETLKSFLKVSFNSH.WETDLVWDTPDKSSKGGTKVEKFVFTTA...FKISNW
Q21883_CAEEL/44-838MMEDEEGDTN.........KTALEPFSKAAMSEFLAWPEFQH.WNGFVKFD.......KNGMLSKYWATVSYHGEGLGDF
O16530_CAEEL/48-891EEEDEELAIQFTVNGSQVVTPSQPFGQGNELRQFLEWPEFSF.WKGFIQVN......ESTYQMSKFLVTTAYHGSDLVDW
Q19945_CAEEL/49-901VEDTER.................LW..KTKLNSWLKYTGGSTQWASNLKIN......KTDGSFQAFRFQIA..LKNFVEP
Q09938_CAEEL/52-945YLNDNRE................SW.IVGVYEWSQLFAFYKL.WSQDFVWA..NESDYDTLELKSYRFRIG..VHRLSTP

PF12349

A1CTG5_ASPCL/632-787--------------------------------------------------------------------------------
A1Z6J2_DROME/390-543--------------------------------------------------------------------------------
PTC2_MOUSE/418-570--------------------------------------------------------------------------------
A4S8G2_OSTLU/258-409--------------------------------------------------------------------------------
A5E1Z8_LODEL/460-615--------------------------------------------------------------------------------
A7RI14_NEMVE/240-393--------------------------------------------------------------------------------
A7RNK5_NEMVE/879-1035--------------------------------------------------------------------------------
A7S0G1_NEMVE/641-795--------------------------------------------------------------------------------
NPC1_HUMAN/649-803--------------------------------------------------------------------------------
SCAP_SCHPO/257-410--------------------------------------------------------------------------------
P91346_CAEEL/298-449--------------------------------------------------------------------------------
PTR9_CAEEL/288-439--------------------------------------------------------------------------------
Q16VL3_AEDAE/637-791--------------------------------------------------------------------------------
Q17FP9_AEDAE/355-509--------------------------------------------------------------------------------
Q17N28_AEDAE/360-513--------------------------------------------------------------------------------
Q18968_CAEEL/295-448--------------------------------------------------------------------------------
Q29GK5_DROPS/626-780--------------------------------------------------------------------------------
Q2HB50_CHAGB/263-415--------------------------------------------------------------------------------
A0A0D1C6G9_USTMA/410-564--------------------------------------------------------------------------------
B4Q8Q7_DROSI/652-804--------------------------------------------------------------------------------
F7ANF6_MACMU/1-147--------------------------------------------------------------------------------
G1MH71_AILME/663-814--------------------------------------------------------------------------------
H3CDQ1_TETNG/587-739--------------------------------------------------------------------------------
Q23E28_TETTS/401-549--------------------------------------------------------------------------------
Q7S7Y9_NEUCR/315-463--------------------------------------------------------------------------------

PF03176

MMPL8_MYCTU/74-402--------------------------------------------------------------------------------
MMPL8_MYCTU/676-1049--------------------------------------------------------------------------------
MMPL4_MYCTU/59-388--------------------------------------------------------------------------------
MMPL5_MYCTU/63-393--------------------------------------------------------------------------------
MMPL5_MYCTU/612-950--------------------------------------------------------------------------------
MMPLB_STRCO/48-383--------------------------------------------------------------------------------
MMPL4_MYCLE/57-385--------------------------------------------------------------------------------
MMPL7_MYCTU/74-391--------------------------------------------------------------------------------
MMPLA_MYCTU/29-358--------------------------------------------------------------------------------
MMPL1_MYCTU/52-381--------------------------------------------------------------------------------
MMPL1_MYCTU/600-941--------------------------------------------------------------------------------
MMPL9_MYCTU/58-387--------------------------------------------------------------------------------
MMPL9_MYCTU/606-944--------------------------------------------------------------------------------
YDFJ_BACSU/44-362--------------------------------------------------------------------------------
YDGH_BACSU/39-360--------------------------------------------------------------------------------
MMPL6_MYCTU/28-366--------------------------------------------------------------------------------
MMPL2_MYCTU/54-382--------------------------------------------------------------------------------
MMPL2_MYCTU/601-939--------------------------------------------------------------------------------
MMPLA_MYCLE/55-391--------------------------------------------------------------------------------
Q50086_MYCLR/31-369--------------------------------------------------------------------------------
MMPLC_MYCTU/55-384--------------------------------------------------------------------------------
MMPLC_MYCTU/658-1001--------------------------------------------------------------------------------
MMPLA_STRCO/46-370--------------------------------------------------------------------------------
MMPLA_STRCO/397-682--------------------------------------------------------------------------------
Q9RKC1_STRCO/44-379--------------------------------------------------------------------------------
Q9RL63_STRCO/44-395--------------------------------------------------------------------------------
MMPLD_STRCO/50-373--------------------------------------------------------------------------------
A0A042QG29_MYCTX/43-376--------------------------------------------------------------------------------
A0A042QG29_MYCTX/595-943--------------------------------------------------------------------------------
Q9XCF5_MYCAV/55-384--------------------------------------------------------------------------------
Q9XCF5_MYCAV/604-943--------------------------------------------------------------------------------
Q9XCF6_MYCAV/51-382--------------------------------------------------------------------------------
Q9XCF6_MYCAV/601-939--------------------------------------------------------------------------------
Q9Z577_STRCO/40-368--------------------------------------------------------------------------------

PF00873

CZCA_RALME/5-1037RGRDIGSFVPEAEAAIQSQVKIPAGYWMTWGGTFEQLQSATTRLQVVVPVALLLVFVLLFAMFNNIKDGLLVFTGIPFAL
MEXB_PSEAE/1-1028APGLSSGDAMAAVEEIVKQ..LPKGVGYSWTGLSYEERLSGSQAPALYALSLLVVFLCLAALYESWSIPFSVMLVVPLGV
MDTB_ECOLI/12-1023PDNYSLGDAVQAIMDTEKTLNLPVDITTQFQGSTLAFQSALGSTVWLIVAAVVAMYIVLGILYESFIHPITILSTLPTAG
ACRF_ECOLI/1-1029APGTSSGDAMALMENLASK..LPAGIGYDWTGMSYQERLSGNQAPALVAISFVVVFLCLAALYESWSIPVSVMLVVPLGI
P74461_SYNY3/10-1047VEGASLSEALTEVDQVLSAMEFPPGVSRLPSTAAASNEQLQSSLVILGGLAAFLVFVVMAVQYNSLLDPLVIMFTLPLAL
O25622_HELPY/6-1014VGRDLKSFVEEAKKVIAQNIKLPPSYYITYGGQFENQQRANKRLSTVIPLSILAIFFILFFTFKSIPLALLILLNIPFAV
MDTF_ECOLI/1-1028AAGKSTGDAMKFMADLVAK..LPAGVGYSWTGLSYQEALSSNQAPALYAISLVVVFLALAALYESWSIPFSVMLVVPLGV
Q55935_SYNY3/9-1024AERDLGSVVEDVQAQIKEKVQLPQGYFIEYGGQFESEQRATNSLLLFSFVAALVIGILMFFSVKSLPATIAIMINLPLAL
ACRB_ECOLI/1-1030APGKSTGEAMELMEQLASK..LPTGVGYDWTGMSYQERLSGNQAPSLYAISLIVVFLCLAALYESWSIPFSVMLVVPLGV
MDTC_ECOLI/3-1009PTGKSLSDASAAIDRAMTQLGVPSTVRGSFAGTAQVFQETMNSQVILIIAAIATVYIVLGILYESYVHPLTILSTLPSAG
ACRD_ECOLI/1-1027APGVSTGTAMDIMESLVKQ..LPNGFGLEWTAMSYQERLSGAQAPALYAISLLVVFLCLAALYESWSVPFSVMLVVPLGV
P73998_SYNY3/2-1028NFGVSTGQAMNAMAAIARQ.VMPPGFDFQWSGISLEEMGSQGQAPLIFGLGLLFVFLVLAAQYENYIDPVIILLSVPLAI
O25328_HELPY/1-1011NAGVSLGEILTQVSKNTKE.WLVEGANYRFTGEADNAKESNGEFLVALATAFVLIYMILAALYESILEPFIIMVTMPLSF
Q5ZWS7_LEGPH/6-1036RNRDLSSFVNEAKQRIEQKVKVPSGYWITWGGQFEQLQSASQRLQIVVPITLLGIFLLLFMSFGNARNALLVFSGIPLAL
Q9I0Y8_PSEAE/3-1040AAGYSSGQAQAAIEKLLKE.ELPNGMTYEWTELTYQQILAGNTALFVFPLCVLLAFLVLAAQYESWSLPLAVILIVPMTL

PF02355

SECF_METTH/102-285--------------------------------------------------------------------------------
SECF_BORBU/108-297--------------------------------------------------------------------------------
SECDF_BACSU/540-729--------------------------------------------------------------------------------
SECF_STRCO/109-305--------------------------------------------------------------------------------
SECF_HAEIN/120-308--------------------------------------------------------------------------------
SECF_ECOLI/114-302--------------------------------------------------------------------------------
SECF_SYNY3/108-301--------------------------------------------------------------------------------
SECF_RICPR/110-299--------------------------------------------------------------------------------
SECF_HELPY/106-293--------------------------------------------------------------------------------
SECF_RHOCB/123-311--------------------------------------------------------------------------------
SECF_METJA/88-276--------------------------------------------------------------------------------
SECF_TREPA/222-411--------------------------------------------------------------------------------
Q9ZBS8_STRCO/569-757--------------------------------------------------------------------------------
SECF_RHOS4/117-305--------------------------------------------------------------------------------
O84454_CHLTR/1200-1393--------------------------------------------------------------------------------
SECF_MYCLE/183-379--------------------------------------------------------------------------------
SECF_AQUAE/92-279--------------------------------------------------------------------------------

PF02460

O16307_CAEEL/1-766STREKLQKQWRGVAHEYEH..FNVTVFQSYSFYIDQLDSIGATTMSTVIWAAITMDLACLLMIPGINSILTSTIAMISIN
P91129_CAEEL/47-858MDQTDATMSFREVAARWPE..FNVTTFMPIWMFTDQYIIIIPNTVQNIIIALLVMIVIAVLFIPQPMCSLWVALACASID
O44978_CAEEL/31-791AERARAMQHIRTILHEESQ..FNATLFDCDSAILSIILTVGTDLIGSIAVTVVCMAIVCFVFIANFNAVAVITSVIASIC
Q18129_CAEEL/47-926TDHTHSCKLMRSIADKYSM..FNVTTFHEYYPFADQYLELTPSLFQNMISDLCTIFAVSWVMIPELICAVAIVLSIASIN
O61894_CAEEL/44-830NIRTSLLLTWRNITSSYPE..FDALVFDENNFYSDQMLELQSTILSSLGTAIILLSAICIMFIAESYIVFWVVCTLISMD
Q21883_CAEEL/44-838QVRRRMLNRWRATADQFAP..LNVSIFDDYAPFVDTLETILPATISTSVCTLICMMIVCFLFMYNVFTVFVATLAITSIC
O16530_CAEEL/48-891SNRAKLLNEWRSVADQDKFKSLNVTVYEEDAKFLDLIETMSPVAIQSALWTFASMFLVAALFISHPPTLFVATFSILSTS
Q19945_CAEEL/49-901NDHKHAAQLLRDIAD.HQP..FNVVVYHEAFPFADQYLIILPATIQNVVISLLCMAVVSFLLVPSLPSGFVIFVSIVSIN
Q09938_CAEEL/52-945TDLVLITEELRGVADRHPD..LNIVTYQQSRAIADQLNVILSSTITNDTLAMFCMFCVALIFIPNPICALFITFAMVTID

PF12349

A1CTG5_ASPCL/632-787--------------------------------------------------------------------------------
A1Z6J2_DROME/390-543--------------------------------------------------------------------------------
PTC2_MOUSE/418-570--------------------------------------------------------------------------------
A4S8G2_OSTLU/258-409--------------------------------------------------------------------------------
A5E1Z8_LODEL/460-615--------------------------------------------------------------------------------
A7RI14_NEMVE/240-393--------------------------------------------------------------------------------
A7RNK5_NEMVE/879-1035--------------------------------------------------------------------------------
A7S0G1_NEMVE/641-795--------------------------------------------------------------------------------
NPC1_HUMAN/649-803--------------------------------------------------------------------------------
SCAP_SCHPO/257-410--------------------------------------------------------------------------------
P91346_CAEEL/298-449--------------------------------------------------------------------------------
PTR9_CAEEL/288-439--------------------------------------------------------------------------------
Q16VL3_AEDAE/637-791--------------------------------------------------------------------------------
Q17FP9_AEDAE/355-509--------------------------------------------------------------------------------
Q17N28_AEDAE/360-513--------------------------------------------------------------------------------
Q18968_CAEEL/295-448--------------------------------------------------------------------------------
Q29GK5_DROPS/626-780--------------------------------------------------------------------------------
Q2HB50_CHAGB/263-415--------------------------------------------------------------------------------
A0A0D1C6G9_USTMA/410-564--------------------------------------------------------------------------------
B4Q8Q7_DROSI/652-804--------------------------------------------------------------------------------
F7ANF6_MACMU/1-147--------------------------------------------------------------------------------
G1MH71_AILME/663-814--------------------------------------------------------------------------------
H3CDQ1_TETNG/587-739--------------------------------------------------------------------------------
Q23E28_TETTS/401-549--------------------------------------------------------------------------------
Q7S7Y9_NEUCR/315-463--------------------------------------------------------------------------------

PF03176

MMPL8_MYCTU/74-402--------------------------------------------------------------------------------
MMPL8_MYCTU/676-1049--------------------------------------------------------------------------------
MMPL4_MYCTU/59-388--------------------------------------------------------------------------------
MMPL5_MYCTU/63-393--------------------------------------------------------------------------------
MMPL5_MYCTU/612-950--------------------------------------------------------------------------------
MMPLB_STRCO/48-383--------------------------------------------------------------------------------
MMPL4_MYCLE/57-385--------------------------------------------------------------------------------
MMPL7_MYCTU/74-391--------------------------------------------------------------------------------
MMPLA_MYCTU/29-358--------------------------------------------------------------------------------
MMPL1_MYCTU/52-381--------------------------------------------------------------------------------
MMPL1_MYCTU/600-941--------------------------------------------------------------------------------
MMPL9_MYCTU/58-387--------------------------------------------------------------------------------
MMPL9_MYCTU/606-944--------------------------------------------------------------------------------
YDFJ_BACSU/44-362--------------------------------------------------------------------------------
YDGH_BACSU/39-360--------------------------------------------------------------------------------
MMPL6_MYCTU/28-366--------------------------------------------------------------------------------
MMPL2_MYCTU/54-382--------------------------------------------------------------------------------
MMPL2_MYCTU/601-939--------------------------------------------------------------------------------
MMPLA_MYCLE/55-391--------------------------------------------------------------------------------
Q50086_MYCLR/31-369--------------------------------------------------------------------------------
MMPLC_MYCTU/55-384--------------------------------------------------------------------------------
MMPLC_MYCTU/658-1001--------------------------------------------------------------------------------
MMPLA_STRCO/46-370--------------------------------------------------------------------------------
MMPLA_STRCO/397-682--------------------------------------------------------------------------------
Q9RKC1_STRCO/44-379--------------------------------------------------------------------------------
Q9RL63_STRCO/44-395--------------------------------------------------------------------------------
MMPLD_STRCO/50-373--------------------------------------------------------------------------------
A0A042QG29_MYCTX/43-376--------------------------------------------------------------------------------
A0A042QG29_MYCTX/595-943--------------------------------------------------------------------------------
Q9XCF5_MYCAV/55-384--------------------------------------------------------------------------------
Q9XCF5_MYCAV/604-943--------------------------------------------------------------------------------
Q9XCF6_MYCAV/51-382--------------------------------------------------------------------------------
Q9XCF6_MYCAV/601-939--------------------------------------------------------------------------------
Q9Z577_STRCO/40-368--------------------------------------------------------------------------------

PF00873

CZCA_RALME/5-1037TGGILALWIRGIPMSITAAVGFIALCGVAVLNGLVMLSFIRSLRE.EGHSLDSAVRVGALTRLRPVLMTALVASLGFVPM
MEXB_PSEAE/1-1028IGALLATSMRGLSNDVFFQVGLLTTIGLSAKNAILIVEFAKELHE.QGKGIVEAAIEACRMRLRPIVMTSLAFILGVVPL
MDTB_ECOLI/12-1023VGALLALLIAGSELDVIAIIGIILLIGIVKKNAIMMIDFALAAEREQGMSPREAIYQACLLRFRPILMTTLAALLGALPL
ACRF_ECOLI/1-1029VGVLLAATLFNQKNDVYFMVGLLTTIGLSAKNAILIVEFAKDLMEKEGKGVVEATLMAVRMRLRPILMTSLAFILGVLPL
P74461_SYNY3/10-1047AGGILGLYVTQTAIGATVIVGTVLLVGIVVNNAIIMVELANQIWAEEGISREAAILRAAPQRLRPILMTTITTVLGMFPL
O25622_HELPY/6-1014TGGLIALFAVGEYISVPASVGFIALFGIAVLNGVVMIGYFKELLLQGKS.VEECVLLGAKRRLRPVLMTACIAGLGLLPL
MDTF_ECOLI/1-1028VGALLATDLRGLSNDVYFQVGLLTTIGLSAKNAILIVEFAVEMMQKEGKTPIEAIIEAARMRLRPILMTSLAFILGVLPL
Q55935_SYNY3/9-1024IGGLLSVVFTGGVISIASLVGFITLFGVAVRNGLLLVDNYNQKFAQGMK.LKETIFKGSMERVNAILMTALTSALGMLPL
ACRB_ECOLI/1-1030IGALLAATFRGLTNDVYFQVGLLTTIGLSAKNAILIVEFAKDLMDKEGKGLIEATLDAVRMRLRPILMTSLAFILGVMPL
MDTC_ECOLI/3-1009VGALLALELFNAPFSLIALIGIMLLIGIVKKNAIMMVDFALEAQRHGNLTPQEAIFQACLLRFRPIMMTTLAALFGALPL
ACRD_ECOLI/1-1027IGALLATWMRGLENDVYFQVGLLTVIGLSAKNAILIVEFANEMNQ.KGHDLFEATLHACRQRLRPILMTSLAFIFGVLPM
P73998_SYNY3/2-1028LGALTAQSLRGFPNDVYCQIGLVMLIGLSSKNAILIVEFANQLRA.EGYPIAKAALEASKDRLRPILMTALSTLFGIFPL
O25328_HELPY/1-1011SGAFFALGLVHQPLSMFSMIGLILLIGMVGKNATLLIDVANEERK.KGLNIQEAILFAGKTRLRPILMTTIAMVCGMLPL
Q5ZWS7_LEGPH/6-1036TGGVFALWLRGIPLSISAGVGFIALSGVAVLNGLVMITFINKLREQKKYYLKDAVLQGSLARLRPVLMTALVASLGFVPM
Q9I0Y8_PSEAE/3-1040LSAITGVILAGSDNNIFTQIGLIVLVGLACKNAILIVEFAKDKQE.EGMDRVAAVLEACRLRLRPILMTSIAFIMGVVPL

PF02355

SECF_METTH/102-285--------------------------------------------------------------------------------
SECF_BORBU/108-297--------------------------------------------------------------------------------
SECDF_BACSU/540-729--------------------------------------------------------------------------------
SECF_STRCO/109-305--------------------------------------------------------------------------------
SECF_HAEIN/120-308--------------------------------------------------------------------------------
SECF_ECOLI/114-302--------------------------------------------------------------------------------
SECF_SYNY3/108-301--------------------------------------------------------------------------------
SECF_RICPR/110-299--------------------------------------------------------------------------------
SECF_HELPY/106-293--------------------------------------------------------------------------------
SECF_RHOCB/123-311--------------------------------------------------------------------------------
SECF_METJA/88-276--------------------------------------------------------------------------------
SECF_TREPA/222-411--------------------------------------------------------------------------------
Q9ZBS8_STRCO/569-757--------------------------------------------------------------------------------
SECF_RHOS4/117-305--------------------------------------------------------------------------------
O84454_CHLTR/1200-1393--------------------------------------------------------------------------------
SECF_MYCLE/183-379--------------------------------------------------------------------------------
SECF_AQUAE/92-279--------------------------------------------------------------------------------

PF02460

O16307_CAEEL/1-766IGVFGLLSMWRVNLDPITMCTTLMSIGFSVDFTAHISYHYYRNPTS...WTTDERLADALKSIGWPMIQAASSTVLCIFP
P91129_CAEEL/47-858FGVIGYMTLWGVNLDAISMITIIMSIGFSVDYSAHIAYGYVVSRED....TAAGRVKEALSALGWPLSQGAMSTIIAVSV
O44978_CAEEL/31-791YVLVGGLSLWGADLDPVIQVDVLLATGFSVDYTAHVAYNFFRARG.....TPQERVYSSLAEMAMPMCEAGLSTFLCMLP
Q18129_CAEEL/47-926VGVLGFMSFWGVNLDSVSIITVIMCIGFSVDLSAHIAYAFSQSYG.....NSHARAVAALETLGWPVFLGASSTVLGILL
O61894_CAEEL/44-830IGTAGLLSLWGADLDPMTVVNILMSIGQCIDFATHVGIRIYRSEYS....DPDERIRDAMGAIGWPVVQAGTSTLLAIVV
Q21883_CAEEL/44-838IGVFGFLSMWGIDLDPISMACLIMSIGFSVDFPAHITFHYFREGLHDPQSTPAKRVARSLAAIGFPLLQCGLSTILFVLC
O16530_CAEEL/48-891LGVFGIMSWWGADLDPIMMSATVMSIGFSVDIPSHVSYHFYQTAKDT..SDIRRRLQMTIEAVGFPIFEASLSTSLCVMS
Q19945_CAEEL/49-901IGVFGYMTLWGVNLDAVSMISIIMSIGFAVDLSAHIIYAFVTSHG.....DTKQRVIGALETLGWPIFQGASSTIAGISI
Q09938_CAEEL/52-945IGVIGFLSLWSVKLDPISMITIIMSIGFSIEFSAHITHGFVSNDSN...LSAFDRCVDAMEKLAWPVVHGSLSTILGVFV

PF12349

A1CTG5_ASPCL/632-787-----------------------------------------
A1Z6J2_DROME/390-543-----------------------------------------
PTC2_MOUSE/418-570-----------------------------------------
A4S8G2_OSTLU/258-409-----------------------------------------
A5E1Z8_LODEL/460-615-----------------------------------------
A7RI14_NEMVE/240-393-----------------------------------------
A7RNK5_NEMVE/879-1035-----------------------------------------
A7S0G1_NEMVE/641-795-----------------------------------------
NPC1_HUMAN/649-803-----------------------------------------
SCAP_SCHPO/257-410-----------------------------------------
P91346_CAEEL/298-449-----------------------------------------
PTR9_CAEEL/288-439-----------------------------------------
Q16VL3_AEDAE/637-791-----------------------------------------
Q17FP9_AEDAE/355-509-----------------------------------------
Q17N28_AEDAE/360-513-----------------------------------------
Q18968_CAEEL/295-448-----------------------------------------
Q29GK5_DROPS/626-780-----------------------------------------
Q2HB50_CHAGB/263-415-----------------------------------------
A0A0D1C6G9_USTMA/410-564-----------------------------------------
B4Q8Q7_DROSI/652-804-----------------------------------------
F7ANF6_MACMU/1-147-----------------------------------------
G1MH71_AILME/663-814-----------------------------------------
H3CDQ1_TETNG/587-739-----------------------------------------
Q23E28_TETTS/401-549-----------------------------------------
Q7S7Y9_NEUCR/315-463-----------------------------------------

PF03176

MMPL8_MYCTU/74-402-----------------------------------------
MMPL8_MYCTU/676-1049-----------------------------------------
MMPL4_MYCTU/59-388-----------------------------------------
MMPL5_MYCTU/63-393-----------------------------------------
MMPL5_MYCTU/612-950-----------------------------------------
MMPLB_STRCO/48-383-----------------------------------------
MMPL4_MYCLE/57-385-----------------------------------------
MMPL7_MYCTU/74-391-----------------------------------------
MMPLA_MYCTU/29-358-----------------------------------------
MMPL1_MYCTU/52-381-----------------------------------------
MMPL1_MYCTU/600-941-----------------------------------------
MMPL9_MYCTU/58-387-----------------------------------------
MMPL9_MYCTU/606-944-----------------------------------------
YDFJ_BACSU/44-362-----------------------------------------
YDGH_BACSU/39-360-----------------------------------------
MMPL6_MYCTU/28-366-----------------------------------------
MMPL2_MYCTU/54-382-----------------------------------------
MMPL2_MYCTU/601-939-----------------------------------------
MMPLA_MYCLE/55-391-----------------------------------------
Q50086_MYCLR/31-369-----------------------------------------
MMPLC_MYCTU/55-384-----------------------------------------
MMPLC_MYCTU/658-1001-----------------------------------------
MMPLA_STRCO/46-370-----------------------------------------
MMPLA_STRCO/397-682-----------------------------------------
Q9RKC1_STRCO/44-379-----------------------------------------
Q9RL63_STRCO/44-395-----------------------------------------
MMPLD_STRCO/50-373-----------------------------------------
A0A042QG29_MYCTX/43-376-----------------------------------------
A0A042QG29_MYCTX/595-943-----------------------------------------
Q9XCF5_MYCAV/55-384-----------------------------------------
Q9XCF5_MYCAV/604-943-----------------------------------------
Q9XCF6_MYCAV/51-382-----------------------------------------
Q9XCF6_MYCAV/601-939-----------------------------------------
Q9Z577_STRCO/40-368-----------------------------------------

PF00873

CZCA_RALME/5-1037AIATGTGAEVQRPLATVVIGGILSSTALTLLVLPVLYRLAH
MEXB_PSEAE/1-1028AISTGAGSGSQHAIGTGVIGGMVTATVLAIFWVPLFYVAVS
MDTB_ECOLI/12-1023MLSTGVGAELRRPLGIGMVGGLIVSQVLTLFTTPVIYLLFD
ACRF_ECOLI/1-1029AISNGAGSGAQNAVGIGVMGGMVSATLLAIFFVPVFFVVIR
P74461_SYNY3/10-1047ALGIGQGSELLQPLGIVVFSGLSLATLLTLFLIPCLYVLLH
O25622_HELPY/6-1014LFSHSVGSEVQKPLAIVVLGGLVTSSALTLLLLPPMFMLIA
MDTF_ECOLI/1-1028VISHGAGSGAQNAVGTGVMGGMFAATVLAIYFVPVFFVVVE
Q55935_SYNY3/9-1024ATASSAGNEILQPLAIVVLGGLCTSTALTLLVLPALYAKFG
ACRB_ECOLI/1-1030VISTGAGSGAQNAVGTGVMGGMVTATVLAIFFVPVFFVVVR
MDTC_ECOLI/3-1009VLSGGDGSELRQPLGITIVGGLVMSQLLTLYTTPVVYLFFD
ACRD_ECOLI/1-1027ATSTGAGSGGQHAVGTGVMGGMISATILAIYFVPLFFVLVR
P73998_SYNY3/2-1028AIATGAGAGSRQALGTAVFGGMLVATFLSLFVVPVLYIVVK
O25328_HELPY/1-1011ALASGDGAAMKSPIGIAMSGGLMISMVLSLLIVPVFYRLLA
Q5ZWS7_LEGPH/6-1036ALATGTGSEVQRPLATVVIGGIISSTFLTLLVLPGLYYIFH
Q9I0Y8_PSEAE/3-1040VISTGAGAEMRHAMGVAVFSGMIGVTFFGLLLTPVFYVLIR

PF02355

SECF_METTH/102-285-----------------------------------------
SECF_BORBU/108-297-----------------------------------------
SECDF_BACSU/540-729-----------------------------------------
SECF_STRCO/109-305-----------------------------------------
SECF_HAEIN/120-308-----------------------------------------
SECF_ECOLI/114-302-----------------------------------------
SECF_SYNY3/108-301-----------------------------------------
SECF_RICPR/110-299-----------------------------------------
SECF_HELPY/106-293-----------------------------------------
SECF_RHOCB/123-311-----------------------------------------
SECF_METJA/88-276-----------------------------------------
SECF_TREPA/222-411-----------------------------------------
Q9ZBS8_STRCO/569-757-----------------------------------------
SECF_RHOS4/117-305-----------------------------------------
O84454_CHLTR/1200-1393-----------------------------------------
SECF_MYCLE/183-379-----------------------------------------
SECF_AQUAE/92-279-----------------------------------------

PF02460

O16307_CAEEL/1-766LMFNTSYMVWVFVKTILLVTVLGLLHGIIFLPALLLTSGD-
P91129_CAEEL/47-858LADIPAYMIVTFFKTVVLSISLGLLHGLVFLPVLLSIFVR-
O44978_CAEEL/31-791LIFVPTYAIVCFAKTVFLVVAIGLLHGLFILPVILALFSK-
Q18129_CAEEL/47-926LTLVDSYIVQIFFKTVFLVINFSILHGLIFLPIFLMKVVR-
O61894_CAEEL/44-830MLMVPSSAVRMFARTSVLVVGTGFFHGLIILPIIVRSFAT-
Q21883_CAEEL/44-838LLFVPTYMGEVFVKTMILVVTLGLIHGLFIVPAFLCAFTA-
O16530_CAEEL/48-891LFFVDLNMAQIFAKCMLLVVVIGMVHGMLVMPVIFALLDT-
Q19945_CAEEL/49-901LYTVDAYIILVFFKTIWLTMLIGAIHGLFFIPIFLSLFPV-
Q09938_CAEEL/52-945LAFIDSYMVLVFFKTISLVLIIGAWHALMLLPILLSMCIP-

This alignment is coloured according to the ClustalX colouring scheme:

 
Glycine (G)
 
Proline (P)
 
Small or hydrophobic (C,A,V,L,I,M,F,W)
 
Hydroxyl or amine amino acids (S,T,N,Q)
 
Charged amino-acids (D,E,R,K)
 
Histidine or tyrosine (H,Y)

For UniProt-based alignments, we also add some additional mark-up to the alignments where appropriate. Active site information is shown as follows:

 
Active site (residue annotated in SwissProt as an active site)
 
Predicted active site (residue aligns in a Pfam alignment with a SwissProt active site)
 
Predicted active site (residue annotated in SwissProt as a potential active site)

Some UniProt sequences can be mapped to protein structures, in which case we also show the secondary structure definition. These lines are shown below the sequence to which they apply and are marked (SS). The meaning of each of the symbols is as follows:

C
Random coil
H
Alpha-helix
G
3(10) helix
I
Pi-helix
E
Hydrogen bonded beta-strand (extended strand)
B
Residue in isolated beta-bridge
T
H-bonded turn (3-turn, 4-turn, or 5-turn)
S
Bend (five-residue bend centered at residue i)
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