Sequence alignment for CL0326

PF04582

Q83931_9REOV/1-326-MDGLTQQQRREVVGLILSLTSSVTINPGDLTQIRERLSALESANASLSESVNTALSRLTDLSAALGNMATSVAEMKVEL
Q9DPB4_9REOV/1-326-MAGLTPSQRREVVGLILSLTSSANTNCGDLTPVYDRLLSLESAVASLDGSVGVLSQKVSDLESDLQGVVSSLGQANSTL
A7J362_9REOV/1-326-MAGLNPSQRREVVSLILSLTSNVTISHGDLTPIYERLTNLEASTELLHRSISDISTTVSNISANLQDMTHTLDDVTANL
Q9DPB5_9REOV/1-326-MAGLNPLQRREVVSLILSLTSSTTTNPGDLTAVYERLTNLEASTKSLRQSLSSIVSDLSDVSVDLQDTTRALDDAIATL

PF01664

SIGM1_REOVJ/244-462-ISGLPARTGSLEASRIDVVAPPLVIQSTGSTRLLRLM--YEAVDFVVTNNVLTLRNRSVTPTFKFPLELNSADNSVSIH
SIGM1_REOVD/239-454-FDSINSRIGATEQSYVASAVTPLRLNSS..TKVLDML--IDSSTLEIN.SSGQLTVRSTSPNLRYPIADVSGG..IGMS
SIGM1_REOVL/251-469-INELPSRVSTLESAKIDSVLPPLTVREASGVRTLSFG--YDTSDFTIINSVLSLRSRLTLPTYRYPLELDTANNRVQVA

PF00541

SPIKE_ADE02/401-578LWTTPDPSPNCRIHSDNDCKFTLVLTKCG--SQVLATV-----AALAVSGDLSSMTGTVASVSIFLRFDQNGV-----LM

PF04582

Q83931_9REOV/1-326NSLISDVQALRTSLDSSSSELASLSLLVHDHDSSISDLQKESHALSGDITNLNSSVSAQGLTISSLEQRVQALEGGSSTS
Q9DPB4_9REOV/1-326TELSKELRQLSSSVDNLMTSLSDLSTTVSGNQAAIAGIQTSVHANTTDISNLKSSVSAISLNITDLERRVGDIESGSGPN
A7J362_9REOV/1-326DGLRTTVTALQDSVSILSTNVTDLTNTSSAHAATLSSLQTTVDGNSTAISNLKSDVSSNGLAITDLQDRVKSLESTASHG
Q9DPB5_9REOV/1-326KGLNTTVAALQNSVASLSSTVNGLTDISSAHSEALSFLRTTIDGNTVAISNLKGDVSTNGLNIADLQNRMKSLESSTSHG

PF01664

SIGM1_REOVJ/244-462RNYRIRLGQWSGQLEYHTPSLR---------------WNAPVTVNLMRVDDW--------LILSFTRFSTSGILASGKFV
SIGM1_REOVD/239-454PNYRFRQSMWIGIVSYSGSGLN---------------WRVQVNSDIFIVDDY--------IHICLPAFDGFSIADGGDLS
SIGM1_REOVL/251-469DRFGMRTGTWTGQLQYQHPQLS---------------WRANVTLNLMKVDDW--------LVLSFSQMTTNSIMADGKFV

PF00541

SPIKE_ADE02/401-578ENSSLKKHYWN--------------------------FR---NGNSTNANPYTNAVGFMPNLLAYPKTQSQTAKNN----

PF04582

Q83931_9REOV/1-326LLFADPLKLEAGTVSLE-LDPYFCSVSRNLTSYSADAQLMQFQWSVKGEDGATNSIDMDVNAHCHGPRTDYLMSTKQSLT
Q9DPB4_9REOV/1-326LRFVSPLSLSQGVVSLV-MDPYFCSDNQALTSYSTDAQLMQFQWLARGEDGSSSSVDMLVNRHCHGRRTDYMMSTTESFT
A7J362_9REOV/1-326LSFSPPLSVADGVVSLD-MDPYFCSQRVSLTSYSAEAQLMQFRWMARGTNGSSDTIDMTVNAHCHGRRTDYMMSSTGNLT
Q9DPB5_9REOV/1-326LSFSPPLSVADGVVSLD-MDPYFCSQRVSLTSYSAEAKLMQFQWMAKGTSGSSDVIDMTVNAHCHGRRTDYMMSSTGGLT

PF01664

SIGM1_REOVJ/244-462LNFVT--GLSPGWATGS-TEPSTT..TNPLSTTFAAIQFI---------NGSS---------------------------
SIGM1_REOVD/239-454LNFVT--GLLPPLLTGD-TEPAFHNDVVTYGAQTVAIGLS---------SGGA---------------------------
SIGM1_REOVL/251-469INFVS--GLSSGWQTGD-TEPSST..IDPLSTTFAAVQFL---------NNGQ---------------------------

PF00541

SPIKE_ADE02/401-578-------IVSQVYLHGDKTKPMILTITLNGTSESTETSEV----------------------------------------

PF04582

Q83931_9REOV/1-326ITASPATLVFELDRITKLPPDLSRLIPCHGFQQATFPVDISFQRDGVSHSYQVYGTYTSSRVFKITFSPGASGPAVIQFL
Q9DPB4_9REOV/1-326VTGNSVSLVFNLDYITKPPSDMSRLVPRAGFQAASFPVDVSFTRDTTTHAYQVYGAFSSPRVFKITFLTGGTGTANLRFL
A7J362_9REOV/1-326VTSNVVLLTFDLSDITHIPSDLARLVPSAGFQAASFPVDVSFTRDSATHAYQAYGVYSSSRVFTITFPTGGDGTANIRSL
Q9DPB5_9REOV/1-326VTSNAVSLTFSLDYITNMPSDLSRLIPSVGFQAASFPVDVSFTRDSATHSYQVYGAYSSARVFTITFPTGGNGTSNIRFL

PF01664

SIGM1_REOVJ/244-462------------------RVDAFRILGVAEWNAGELEITN-HGGTYTAHTNVDWAP------MTIMYPCLG---------
SIGM1_REOVD/239-454------------------PQYMSKNLWVEQWQDGVLRLRV-EGGGSITHSNSKWPA------MTVSYPRSF---------
SIGM1_REOVL/251-469------------------RIDAFRIMGVSEWTDGELEIKN-YGGTYTGHTQVYWAP------WTIMYPCNV---------

PF00541

SPIKE_ADE02/401-578------------------STYSMSFTWS--WESGKYTTET-FATNSYTFSY-----------------------------

PF04582

Q83931_9REOV/1-326TVRTGIDT
Q9DPB4_9REOV/1-326TVRTGIDT
A7J362_9REOV/1-326TVRTGIDT
Q9DPB5_9REOV/1-326TVRTGIDT

PF01664

SIGM1_REOVJ/244-462--------
SIGM1_REOVD/239-454--------
SIGM1_REOVL/251-469--------

PF00541

SPIKE_ADE02/401-578--------

This alignment is coloured according to the ClustalX colouring scheme:

 
Glycine (G)
 
Proline (P)
 
Small or hydrophobic (C,A,V,L,I,M,F,W)
 
Hydroxyl or amine amino acids (S,T,N,Q)
 
Charged amino-acids (D,E,R,K)
 
Histidine or tyrosine (H,Y)

For UniProt-based alignments, we also add some additional mark-up to the alignments where appropriate. Active site information is shown as follows:

 
Active site (residue annotated in SwissProt as an active site)
 
Predicted active site (residue aligns in a Pfam alignment with a SwissProt active site)
 
Predicted active site (residue annotated in SwissProt as a potential active site)

Some UniProt sequences can be mapped to protein structures, in which case we also show the secondary structure definition. These lines are shown below the sequence to which they apply and are marked (SS). The meaning of each of the symbols is as follows:

C
Random coil
H
Alpha-helix
G
3(10) helix
I
Pi-helix
E
Hydrogen bonded beta-strand (extended strand)
B
Residue in isolated beta-bridge
T
H-bonded turn (3-turn, 4-turn, or 5-turn)
S
Bend (five-residue bend centered at residue i)
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