Sequence alignment for CL0343

PF00129

HLAH_HUMAN/25-203RSHSMRYFYTTMSRPGAGEPRF----------------------ISVGYVDDTQFVRFDSDDASPREEPRAPWMEREG.P
ZA2G_HUMAN/26-201GRYSLTYIYTGLSKHVEDVPAF----------------------QALGSLNDLQFFRYNSKDR..KSQPMGLWRQVEG.M
HA10_MOUSE/25-203GSHSMRYFETSVSRPGLGEPRF----------------------IIVGYVDDTQFVRFDSDAETPRMEPRAPWMEQEG.P
HA15_MOUSE/21-199SPHSLRYFTTAVSRPGLGEPRF----------------------IIVGYVDDTQFVRFDSDAENPRMEPRARWIEQEG.P
1C01_GORGO/25-203GSHSMRYFFTAVAPPGRGEPRF----------------------IAVGYVDDTQFVRFDSDAANTRGEPRAPWVEQEG.P
FCGRN_RAT/25-198PRLPLMYHLAAVSDLSTGLPSF----------------------WATGWLGAQQYLTYNNLRQ..EADPCGAWIWENQVS
HA12_MOUSE/25-203GSHSLRYFVTAVSRPGFGEPRY----------------------MEVGYVDNTEFVRFDSDAENPRYEPRARWIEQEG.P
HA1F_CHICK/23-198ELHTLRYIQTAMTDPGPGQPWF----------------------VTVGYVDGELFVHYNSTAR..RYVPRTEWIAAKADQ
HA17_MOUSE/22-200GQHSLQYFHTAVSRPGLGEPWF----------------------ISVGYVDDTQFVRFDSDAENPRMEPRARWMEQEG.P
HA11_RAT/25-203GSHSLRYFHTAVSRPGLGEPRF----------------------ISVGYVDDTQFVRYDSDAENPRYEPRARWMEREG.P
HA1A_BOVIN/22-200GSHSLRYFSTAVSRPGLGEPRY----------------------LEVGYVDDTQFVQFDSDAPNPRMEPRARWVEQEG.P
HLAG_HUMAN/25-203GSHSMRYFSAAVSRPGRGEPRF----------------------IAMGYVDDTQFVRFDSDSACPRMEPRAPWVEQEG.P
HA1A_RABIT/25-203GSHSMRYFYTSVSRPGLGEPRF----------------------IIVGYVDDTQFVRFDSDAASPRMEQRAPWMGQVE.P
HLAE_HUMAN/22-200GSHSLKYFHTSVSRPGRGEPRF----------------------ISVGYVDDTQFVRFDNDAASPRMVPRAPWMEQEG.S
HA1T_MOUSE/27-205GSHSLRYFYTALSRPAISEPWY----------------------IAVGYLDDTQFVRFNSSGETATYKLSAPWVEQEG.P
1C28_PANTR/22-200GSHSLRYFSTAVSRPGRGEPRY----------------------IAVEYVDDTQFLRFDSDAAIPRMEPREPWVEQEG.P
HA19_CANFA/25-204GSHSLRYFYTSVSRPGAGDPRF----------------------IAVGYVDDTQFVRFDSDAATGRMEPRAPWVEQEG.P

PF16497

G7NW87_MACFA/1-198MGCLLFLLLWALLQAWGSAEVPQRLFPLRCLQISSFANSNWTRTDGLAWLGELQTHSWSNDSD--TIRSLKPWSQGTFSD
F6RUT0_HORSE/1-198MRCLLFLLLWGLPQIRRTSEVPQRNFPFRCLQISSFLNRSWARTDALAWLGELQPYVWKNDSD--TIRFLKPWSQGTFSD
L7N1C3_MYOLU/1-197MECWPVLLLWGLPQMWASPEAPQSSARLLFLQISPFANSSWTRTDGSFWLGALQTHSWSNGLD--.IHFLRPWSQGKLSD
F6QYN3_HORSE/1-198MLFLQLHLLAVLLPGGDNKDDFQEPVSFQIIQISSFYNGSWVQNLGSGWLDELQTHGWESSSG--TIIFLWPWSKGNYSN
CD1D1_MOUSE/1-200MRYLPWLLLWAFLQVWGQSEAQQKNYTFRCLQMSSFANRSWSRTDSVVWLGDLQTHRWSNDSA--TISFTKPWSQGKLSN
F7DC15_HORSE/1-198MLFLQLPCLAVLLQGGDNKDDFQEPISFQIIQISSFYNRSWVQNLSSGWLGELQTHSCESKSG--TIIFLWPWSKGNFSN
CD1D_SHEEP/1-198MGCLLFLVLLEFQKIWGSFEAPQTSFPFRFLQISSFANHSWTRTDGLMWLGELQPYTWRNESS--TIRFLKHWSQGTFSD
I3MFM6_SPETR/1-196MGCMWFLLLWVLPQAWGSSEGR..SVLFRCLQISSFTNSSWMRTDALAWLGELQTHSWSNASD--TISFVKPWAQGTFSS
G1PVC0_MYOLU/1-198MLFLQIPLLAVLLAAGDNEDAFQEEISFKMIHSSSFYNDSWVKIRYSAWLGDLQTHGWDINSG--RIIFLRPWSKGNLGK
L7N1K8_MYOLU/1-198MLFLQIPLLAVLLAAVDNEDAFQEEISFKIIQSISFYNRSWVKSQNSAWLGDLKTHGWDNNSG--RIIFLRPWSKGNLSK
H0WFT3_OTOGA/1-199MRRLLLLQLWALLRVWGGPEGPQRSISFRCLQISSFSNSSQVRTDGSAWLGELQTHSWVDSSD--AFRFLKPWSQSGFSD
F7BW69_HORSE/1-198MLFLQFALLVVLLPGGDSKDDFQEPTSFRVIYSSSFYNPSRVQALGSAWLGELQTHGWENHTG--SFIFLRPWSKGNFSS
G1QBJ7_MYOLU/1-198MLFLQITFLAVLLAAGDNEDAFQEQISFHMIHISSFYNHSWTQNWGSGWLGELQILGWNSNSY--SVIFLRPWSKGNFSN
M3YN29_MUSPF/1-198MLFLQLVLLVVFLPDGDSEDAVQEPISFQITLTVSFYNRSWTQSLGSAWLDEIQTHGWDNKTG--AFIFLWPWSKGNWSN
F1PZ60_CANFA/1-198MLFLQLVLLVVLLPEGDSEDASQEPVSFQVILTTSFYNSSWTQNLASAWLDELQTHSWDSDSG--TFLFLWPWAKGKLSK
G1L1W7_AILME/2-199MLFLQLVSFVVLLPGGDSEDAFQEPISLRIILTSSFYNRSRTQNLASAWLDELQTHGWDSKTG--AFIFLWPWSRGNLSN
G3HKH3_CRIGR/1-198MRYLTCLLLWVFPRVWGQWEDQLKNYPLRCLQISSFPNSSSFRTDGLAWLGDVQTHSWRNAS.--TVSFLKPWSHGKLSD
G1LFS0_AILME/1-198MLFLQLALLAVLLPGGDGDDDFQEPIYFRVIRTSFLYNRSGTQNLGSIWLDELQTHAWDNKTH--TFTFLWPWSQGNLSN
A0ZPR3_PIG/1-198MLFLQLPLLLVLLPGGDSEEGFQEPISFQIIWISSFYNRSWEEEVCSAWLGELQTHRREGKSD--IVIYRQPWSKGNFSR

PF14586

RAE1C_MOUSE/31-204DAHSLRCNLTIKAPTPADPLWY----------------------EAKCLVDEILILHLSNINK--TMTSGDPGETANA-T

PF00969

DRB3_HUMAN/42-116--------------------------------------------------------------------------------
DRB4_HUMAN/42-116--------------------------------------------------------------------------------
HB2D_CANFA/42-116--------------------------------------------------------------------------------
HB2A_RAT/8-82--------------------------------------------------------------------------------
DOB_HUMAN/39-113--------------------------------------------------------------------------------
DQB2_HUMAN/45-118--------------------------------------------------------------------------------
DPB1_HUMAN/42-114--------------------------------------------------------------------------------
HB2L_CHICK/8-82--------------------------------------------------------------------------------
HB2D_RAT/40-114--------------------------------------------------------------------------------
HB2C_PIG/45-119--------------------------------------------------------------------------------
HB2A_MOUSE/40-114--------------------------------------------------------------------------------
HB21_MOUSE/40-114--------------------------------------------------------------------------------
DMB_HUMAN/27-106--------------------------------------------------------------------------------
O35424_MOUSE/39-113--------------------------------------------------------------------------------
HB2P_RABIT/43-113--------------------------------------------------------------------------------
F1N610_BOVIN/47-117--------------------------------------------------------------------------------
F1NSZ6_CHICK/40-113--------------------------------------------------------------------------------
M3WAZ6_FELCA/46-118--------------------------------------------------------------------------------
M3XET4_FELCA/43-114--------------------------------------------------------------------------------
Q1MTC8_DANRE/29-104--------------------------------------------------------------------------------
Q31099_MOUSE/27-106--------------------------------------------------------------------------------
Q3UUV9_MOUSE/43-114--------------------------------------------------------------------------------
Q58DW7_BOVIN/27-105--------------------------------------------------------------------------------
Q6MGA7_RAT/27-106--------------------------------------------------------------------------------
Q70IB5_BOVIN/44-114--------------------------------------------------------------------------------
W5PC43_SHEEP/40-111--------------------------------------------------------------------------------
W5Q266_SHEEP/32-102--------------------------------------------------------------------------------

PF00993

G3N564_GASAC/36-114--------------------------------------------------------------------------------
G3N551_GASAC/28-106--------------------------------------------------------------------------------
H2L2T1_ORYLA/33-110--------------------------------------------------------------------------------
H2MYR3_ORYLA/32-109--------------------------------------------------------------------------------
M4A196_XIPMA/25-103--------------------------------------------------------------------------------
H2MXB6_ORYLA/22-99--------------------------------------------------------------------------------
M4AFZ0_XIPMA/29-106--------------------------------------------------------------------------------
I3KVG9_ORENI/23-101--------------------------------------------------------------------------------
I3KVH2_ORENI/23-100--------------------------------------------------------------------------------
I3J7S9_ORENI/23-101--------------------------------------------------------------------------------
I3JXB4_ORENI/24-101--------------------------------------------------------------------------------
I3JKK1_ORENI/23-101--------------------------------------------------------------------------------
H2RPE2_TAKRU/21-98--------------------------------------------------------------------------------
H2SD42_TAKRU/22-100--------------------------------------------------------------------------------
H2V674_TAKRU/22-96--------------------------------------------------------------------------------
H3CDM2_TETNG/23-101--------------------------------------------------------------------------------
H3CJ64_TETNG/21-98--------------------------------------------------------------------------------
I3KVG1_ORENI/88-165--------------------------------------------------------------------------------
Q8WM94_DANRE/23-100--------------------------------------------------------------------------------
F1R0K2_DANRE/23-100--------------------------------------------------------------------------------
F1QYA3_DANRE/32-109--------------------------------------------------------------------------------
F1QNN0_DANRE/23-100--------------------------------------------------------------------------------
W5LNP0_ASTMX/25-104--------------------------------------------------------------------------------
W5KCR1_ASTMX/22-100--------------------------------------------------------------------------------
Q1MTC7_DANRE/23-100--------------------------------------------------------------------------------
M9MM93_DANRE/17-99--------------------------------------------------------------------------------
Q6MGB1_RAT/29-108--------------------------------------------------------------------------------
G1L546_AILME/37-114--------------------------------------------------------------------------------
G1PA08_MYOLU/2-81--------------------------------------------------------------------------------
L8Y815_TUPCH/29-108--------------------------------------------------------------------------------
L8Y3F3_TUPCH/29-108--------------------------------------------------------------------------------
L8YBX0_TUPCH/29-108--------------------------------------------------------------------------------
I3M2H3_SPETR/44-123--------------------------------------------------------------------------------
G5BB02_HETGA/33-112--------------------------------------------------------------------------------
HA2P_RABIT/1-80--------------------------------------------------------------------------------
G3TMW3_LOXAF/41-120--------------------------------------------------------------------------------
H0VMA0_CAVPO/42-122--------------------------------------------------------------------------------
H0UYJ7_CAVPO/26-105--------------------------------------------------------------------------------
G1R500_NOMLE/35-114--------------------------------------------------------------------------------
H0WUA6_OTOGA/41-120--------------------------------------------------------------------------------
H2RBA7_PANTR/29-109--------------------------------------------------------------------------------
W5Q1M3_SHEEP/29-109--------------------------------------------------------------------------------
G7P2R3_MACFA/2-81--------------------------------------------------------------------------------
F7GQ21_MACMU/12-91--------------------------------------------------------------------------------
G3RX38_GORGO/29-109--------------------------------------------------------------------------------
F7I518_CALJA/33-113--------------------------------------------------------------------------------
H0VR34_CAVPO/30-110--------------------------------------------------------------------------------
G5BB12_HETGA/29-109--------------------------------------------------------------------------------
W5Q2C6_SHEEP/29-109--------------------------------------------------------------------------------
M3Y3I6_MUSPF/29-109--------------------------------------------------------------------------------
G1QAF8_MYOLU/29-109--------------------------------------------------------------------------------
G1Q5X0_MYOLU/29-109--------------------------------------------------------------------------------
L7N114_MYOLU/30-110--------------------------------------------------------------------------------
G1PGE2_MYOLU/3-83--------------------------------------------------------------------------------
I3MDX2_SPETR/29-109--------------------------------------------------------------------------------
L5KYV0_PTEAL/29-109--------------------------------------------------------------------------------
F6YG75_HORSE/29-109--------------------------------------------------------------------------------
F7D2Z8_MONDO/30-110--------------------------------------------------------------------------------
G1P5L8_MYOLU/30-110--------------------------------------------------------------------------------
G1Q9G7_MYOLU/3-83--------------------------------------------------------------------------------
G1QA26_MYOLU/29-109--------------------------------------------------------------------------------
G3UHX0_LOXAF/29-109--------------------------------------------------------------------------------
O97981_PIG/29-109--------------------------------------------------------------------------------
G3HQS4_CRIGR/268-348--------------------------------------------------------------------------------
K7EUP3_PONAB/29-109--------------------------------------------------------------------------------
G1QBV7_MYOLU/2-82--------------------------------------------------------------------------------
I3N7K0_SPETR/29-108--------------------------------------------------------------------------------
I3MR31_SPETR/27-107--------------------------------------------------------------------------------
F6T370_MONDO/29-109--------------------------------------------------------------------------------
F1ML44_BOVIN/29-109--------------------------------------------------------------------------------
H0WYE3_OTOGA/29-109--------------------------------------------------------------------------------
HA2B_RAT/30-110--------------------------------------------------------------------------------
HA2B_MOUSE/30-110--------------------------------------------------------------------------------
F6ZJJ9_HORSE/29-109--------------------------------------------------------------------------------
F7D2J1_XENTR/21-100--------------------------------------------------------------------------------
F6ZD60_MONDO/30-109--------------------------------------------------------------------------------
A7X5M6_ORNAN/29-108--------------------------------------------------------------------------------
G3UHG4_LOXAF/2-81--------------------------------------------------------------------------------
G3UJA6_LOXAF/27-104--------------------------------------------------------------------------------
G5C3I9_HETGA/21-100--------------------------------------------------------------------------------
HA22_MOUSE/29-108--------------------------------------------------------------------------------
G1L6J1_AILME/29-108--------------------------------------------------------------------------------
U3IBP5_ANAPL/28-111--------------------------------------------------------------------------------
H2ZTM7_LATCH/28-107--------------------------------------------------------------------------------
H2ZYC5_LATCH/4-83--------------------------------------------------------------------------------
F6S093_HUMAN/8-85--------------------------------------------------------------------------------
G5BB05_HETGA/92-169--------------------------------------------------------------------------------
I3MD72_SPETR/41-118--------------------------------------------------------------------------------
G3U806_LOXAF/37-114--------------------------------------------------------------------------------
G3HQS6_CRIGR/42-118--------------------------------------------------------------------------------
Q31621_MOUSE/41-118--------------------------------------------------------------------------------
K7GRZ3_PIG/40-117--------------------------------------------------------------------------------
M3XS77_MUSPF/41-118--------------------------------------------------------------------------------
W5PDP1_SHEEP/41-118--------------------------------------------------------------------------------
W5MK71_LEPOC/37-117--------------------------------------------------------------------------------
W5MKC8_LEPOC/20-100--------------------------------------------------------------------------------

PF00129

HLAH_HUMAN/25-203KYWDRNTQICKAQAQTERENLRIALRYYNQSEGGSHTMQVMYGCDVGP----DGPFLRGYE-QHAYDGKDYIALNEDLRS
ZA2G_HUMAN/26-201EDWKQDSQLQKAREDIFMETLKDIVEYYNDS.NGSHVLQGRFGCEIEN----NR.SSGAFW-KYYYDGKDYIEFNKEIPA
HA10_MOUSE/25-203EYWERETQRAKGNEQSFHVSLRTLLGYYNQSESGSHTIQWMYGCKVGS----DGRFLRGYL-QYAYDGRDYIALNEDLKT
HA15_MOUSE/21-199EYWERETWKARDMGRNFRVNLRTLLGYYNQSNDESHTLQWMYGCDVGP----DGRLLRGYC-QEAYDGQDYISLNEDLRS
1C01_GORGO/25-203EYWDRETQKYKRQAQTDRVSLRKLRGYYNQSEDGSHTFQRMYGCDVGP----DGRLQRGYD-QLAYDGKDYIALNEDLRS
FCGRN_RAT/25-198WYWEKETTDLKSKEQLFLEAIRTLENQIN....GTFTLQGLLGCELAP----DN.SSLPTA-VFALNGEEFMRFNPRTGN
HA12_MOUSE/25-203EYWERETRRAKGNEQSFRVDLRTALRYYNQSAGGSHTLQWMAGCDVES----DGRLLRGYW-QFAYDGCDYIALNEDLKT
HA1F_CHICK/23-198QYWDGQTQIGQGNEQIDRENLGILQRRYNQT.GGSHTVQWMYGCDILE----GG.PIRGYY-QMAYDGRDFTAFDKGTMT
HA17_MOUSE/22-200EYWERETQIAKGHEQSFRGSLRTAQSYYNQSKGGSHTLQWMYGCDMGS----DGRLLRGYL-QFAYEGRDYIALNEDLKT
HA11_RAT/25-203EYWEEQTLVAKGQELDYRVSLRNLLSYYNQSEGGSHTIQRMYGCDVGS----DGSLLRGYE-QHAYDGRDYIALNEDLKT
HA1A_BOVIN/22-200EYWDRNTRNAKGNAQSFRVNLNTLRGYYNQSEAGSHTLQWMSGCDVGP----DGALRRGFM-QYGYDGRDYLALNEDLRS
HLAG_HUMAN/25-203EYWEEETRNTKAHAQTDRMNLQTLRGYYNQSEASSHTLQWMIGCDLGS----DGRLLRGYE-QYAYDGKDYLALNEDLRS
HA1A_RABIT/25-203EYWDQQTQIAKDTAQTFRVNLNTALRYYNQSAAGSHTFQTMFGCEVWA----DGRFFHGYR-QYAYDGADYIALNEDLRS
HLAE_HUMAN/22-200EYWDRETRSARDTAQIFRVNLRTLRGYYNQSEAGSHTLQWMHGCELGP----DRRFLRGYE-QFAYDGKDYLTLNEDLRS
HA1T_MOUSE/27-205EYWARETEIVTSNAQFFRENLQTMLDYYNLSQNGSHTIQVMYGCEVEF----FGSLFRAYE-QHGYDGPDYIALNEDLKT
1C28_PANTR/22-200QYWERTTGYAKANAQTDRVALRNLLRRYNQSEAGSHTLQGMNGCDMGP----DGRLLRGYH-QHAYDGKDYISLNEDLRS
HA19_CANFA/25-204EYWDRQTRTIKETARTFRVDLDTLRGYYNQSEAGSHTRQTMYGCDLGP----DGRLLRGYS-QDAYDGADYIALNEDLRS

PF16497

G7NW87_MACFA/1-198QQWEALQRVFRVYRSSFTRDVKEFAKML..RLAYPMELQVSAGCEVHP----.GNASHNFF-HVAFQGSDILSFQGT--S
F6RUT0_HORSE/1-198QQCEELQHLFRVYRSSVTRDIQEFAKML..HIAYPLEVQVSAGCEVHP----.GNTSESFL-YAAFQGRDILSFQGT--S
L7N1C3_MYOLU/1-197HQWEQLQQVFWVYRSSFNREIREFAKML..HLDYPFVVQVSAGCEVHP----.GSPLKSFF-HSAFQGSDILSFQET--S
F6QYN3_HORSE/1-198EEWMELEKLFRMSSIGIPQMFHNLASQW..QLEYPFEVQITAGCELHF----.GEISVGFM-RGAYQGSDFMSFQNN--S
CD1D1_MOUSE/1-200QQWEKLQHMFQVYRVSFTRDIQELVKMMSPKEDYPIEIQLSAGCEMYP----.GNASESFL-HVAFQGKYVVRFWGT--S
F7DC15_HORSE/1-198EEIMELEKLFHMFSAGFLQAFHEHASQW..QLEYPFQVQTAGGCELHF----.GKASISFM-RVAYQGSDFLSFQNN--S
CD1D_SHEEP/1-198QQWEQLQHTFQVYRSSFTRDIREFVKML..PGDYPFEIQISGGCELLP----.RNISESFL-RAALQEKDVLSFQGM--S
I3MFM6_SPETR/1-196QQWIHLQNTFRVFRSSFIRDIQEFAKML..SLEYPTELQLSGGCEVHP----.GNDSEHFL-HVAHQGEHILSFQGT--A
G1PVC0_MYOLU/1-198EEIKELEEFFRAFSIEMPHELHRHASEW..KFKYPFEIQIRMGCELHP----.GGAIVDFY-GFAYQGSELLHFQNN--S
L7N1K8_MYOLU/1-198KELKELEEYSHKFSTEMPNKFHRHANQW..QLKYPFEIQITRGCELHP----.GGPTVAFY-RYAYQGSEVMHFQNN--S
H0WFT3_OTOGA/1-199QQWERLQHIFRVYRISFTREVQKFVKKL..QVAYPVEIQLSAGCEVRP----GNASSANFL-HVAFQGSDFLSFQGT--S
F7BW69_HORSE/1-198EELTEIEKLFRTFSIEFNQIFHNHASQW..QLAYPFQVQLAMGCELHI----.GEASVGFA-RIAYQGSDLISIQNN--S
G1QBJ7_MYOLU/1-198KEITEMEKFFRRLHIELPPLIRKHASEW..KFEYPFEVQMTGGCELHP----.REGKVVFL-QYAYQGSELLTFQNN--S
M3YN29_MUSPF/1-198VELIKLEKLLYAYFIGLRQVFQDHVRHW..HLEYPFQIQLAEGCELHF----.GEASVGFV-KFAYQGADLTSFQNT--T
F1PZ60_CANFA/1-198EELIERERTFHTFSIRFPLIFQDSVSDW..QLEYPFQVQMAEGCGLYF----.GKPSVGFM-QIAYQGSDLVSFQNK--S
G1L1W7_AILME/2-199EEVIRAEEAFYSNSIGLPLCFHDHFSEW..QLEYPFQVQLTGGCELHF----.GEPSVGFI-RIAYEGSDLVSFQNM--S
G3HKH3_CRIGR/1-198QQWQTLEHILQVYRTSFTRDIQELVKML.PIIHYPIEMQVSAGCEVHS----.GNTSENFF-NVASQGQHILSFQGT--S
G1LFS0_AILME/1-198EEVVTGENLFYSNTILVNQDFREHVSKW..QLEYPFQLQMVIGCELHV----.GKPSVGFM-RIAYQGSDLISFQNV--S
A0ZPR3_PIG/1-198EDLMESEHILRMFFVRFVQAFFNHASQW..KLEYPFDVQIAGGCDLYH----.GETSVGFV-RIAYQGSDFASFQKN--S

PF14586

RAE1C_MOUSE/31-204EVGECLTQPVNDLCQKLRDKVSNTKVDTHKTNGYPH-LQVTMIYPQSQ-----GQTPSATW-EFNISDSYFFTFYTENMS

PF00969

DRB3_HUMAN/42-116-----------------------------------------SECHF.F----NGTERVRYLDRYFHNQEEFLRFDSDVGE
DRB4_HUMAN/42-116-----------------------------------------CECHF.L----NGTERVWNLIRYIYNQEEYARYNSDLGE
HB2D_CANFA/42-116-----------------------------------------SECYF.T----NGTERVRFVERYIHNREEFVRFDSDVGE
HB2A_RAT/8-82-----------------------------------------GLCYY.T----NGTQRIRSVDRRFYNQEEFLRYDSDVGE
DOB_HUMAN/39-113-----------------------------------------ADCYF.T----NGTEKVQFVVRFIFNLEEYVRFDSDVGM
DQB2_HUMAN/45-118-----------------------------------------GMCYF.T----NGTERVRGVARYIYNREEYGRFDSDVGE
DPB1_HUMAN/42-114-----------------------------------------QECYA.F----NGTQRF..LERYIYNREEFARFDSDVGE
HB2L_CHICK/8-82-----------------------------------------VECHF.L----NGTERVRFLVRHVYNRQQYVHFDSDVGL
HB2D_RAT/40-114-----------------------------------------GECHF.Y----NGTQRVRFLARYIYNREEYTRFDSDVGE
HB2C_PIG/45-119-----------------------------------------GECYF.Y----NGTQRVRGVARYIYNQEEHLRFDSDVGE
HB2A_MOUSE/40-114-----------------------------------------GECYF.T----NGTQRIRYVTRYIYNREEYVRYDSDVGE
HB21_MOUSE/40-114-----------------------------------------SECHF.Y----NGTQRVRLLERYFYNLEENLRFDSDVGE
DMB_HUMAN/27-106-----------------------------------------STCLLDD----AGTPKD.FTYCISFNKDLLTCWDPEENK
O35424_MOUSE/39-113-----------------------------------------ADCYF.T----NGTEKVHLLVRFIFNLEEYLHFDSDLGM
HB2P_RABIT/43-113-----------------------------------------YECYA.S----NGTQRL..LDRCAYNREEFVRFDSDIGE
F1N610_BOVIN/47-117-----------------------------------------..CYF.T----NGTERVRYVTRYIYNQEEYVRFDSDWDE
F1NSZ6_CHICK/40-113-----------------------------------------.ECHY.L----NGTERVRYLVRYVYNRQEYAHFDSDVGK
M3WAZ6_FELCA/46-118-----------------------------------------.ECHF.T----NGTERVRYLERHYHNGEENLRFDSEVGE
M3XET4_FELCA/43-114-----------------------------------------.ECHY.P----NGTERVRYLVRFFYNREELARFDNEVGE
Q1MTC8_DANRE/29-104-----------------------------------------QQCFYST----SDYSDMVYLASYSFNKVVDTQFNSSVGK
Q31099_MOUSE/27-106-----------------------------------------STCVLND----AGTPQD.FTYCVSFNKDLLACWDPDVGK
Q3UUV9_MOUSE/43-114-----------------------------------------.ECHY.F----NGKERVWSVTRFIYNQEEFARFNSDFGK
Q58DW7_BOVIN/27-105-----------------------------------------STCVLDD----DGDPKD.FSYCISFNKDLLTCWDPLQAS
Q6MGA7_RAT/27-106-----------------------------------------STCLLDD----EGTPMD.FTYCISFNKDLLACWDPEEGQ
Q70IB5_BOVIN/44-114-----------------------------------------.MCYF.T----NGTEHVRLVARQIYNKEEILHFDSDLGE
W5PC43_SHEEP/40-111-----------------------------------------.DCYF.T----NGTEKVRFVVRFIFNLEEYARFDSDLGM
W5Q266_SHEEP/32-102-----------------------------------------.ECRF.S----NGLQRMRFFARYIYNTKEDVHFDSDVGE

PF00993

G3N564_GASAC/36-114------------------------------------KDIRVLGCS.........DSDGENMFGLDGEEVWYADFKHGKGV
G3N551_GASAC/28-106------------------------------------KDIAIVGCS.........DSDGEEMYGLDGEEVWYADFKHGKGV
H2L2T1_ORYLA/33-110------------------------------------EDFGILGCS.........DYDQEYMYALDGEEKWYADYKKETGV
H2MYR3_ORYLA/32-109------------------------------------EDFQITGCS.........DYDEEFMVNLDGEEIVYTDFKKGTEV
M4A196_XIPMA/25-103------------------------------------EDLAIVGCS.........DSDGEMMYALDGEELWYADFKKGKGV
H2MXB6_ORYLA/22-99------------------------------------EDLAITGCS.........DSDGEDMYALDGEEVWYADFKKQTGV
M4AFZ0_XIPMA/29-106------------------------------------DSFRVIGCS.........DTDGLDMMTLDGEEVWHADFIHETGV
I3KVG9_ORENI/23-101------------------------------------SDIAINGCS.........DSDGEFMYGLDGEEKWYADFNKHTGV
I3KVH2_ORENI/23-100------------------------------------SDIAIGGCS.........ESDGENMYGLDGEEIAYADFNKQEFI
I3J7S9_ORENI/23-101------------------------------------SDIAVGGCS.........ESDEENMYGLDGEELAYTDFNKKEEI
I3JXB4_ORENI/24-101------------------------------------GDVHINGCS.........DFDAEDMYGLDGEEVAYADFNNHTEV
I3JKK1_ORENI/23-101------------------------------------TDIHVIGCS.........DFNGEVMFGLDREELWYADFEKQMGV
H2RPE2_TAKRU/21-98------------------------------------KDIRITGCS.........DLDGEDMFGLDSEELWYADFSKGEGV
H2SD42_TAKRU/22-100------------------------------------EDIRILGCS.........DLDGEFMYGLDSEEVWYADFSKGEGV
H2V674_TAKRU/22-96------------------------------------KDIGIVGCS.........DLDGEFMYGLDSEELWYADFSKGEGV
H3CDM2_TETNG/23-101------------------------------------EDVHIRGCS.........DFDGEDMYGLDGEERWYADFKRGEGV
H3CJ64_TETNG/21-98------------------------------------EDIRIVGCS.........DFDGEYMHGLDGEELWYADFRRGEGV
I3KVG1_ORENI/88-165------------------------------------EDIGIVGCS.........DSDGEDMYGLDGEEVRYADFKKQEDI
Q8WM94_DANRE/23-100------------------------------------EDFAIRGCS.........DTEKEDTYGMDEEELWHADFNQKKGV
F1R0K2_DANRE/23-100------------------------------------EELEIYVCS.........DSESEAMVGADGEELWHADFKQKTGI
F1QYA3_DANRE/32-109------------------------------------NLFMFNGCS.........DTEKEALYGSEGEEMWHSDFKLKQGV
F1QNN0_DANRE/23-100------------------------------------EVNQIQVCS.........NTEQEFFIGYDGEEIWHADIAHRRGV
W5LNP0_ASTMX/25-104------------------------------------EYYVFDWCS.........ETDGGVVWMIDGEEEYHADFKDGRGV
W5KCR1_ASTMX/22-100------------------------------------KDIFLTICS.........ETFGEQIYGLDGEEKWHADFNLQEGV
Q1MTC7_DANRE/23-100------------------------------------KDFGFVGCS.........DMEKEFLFGFDGEELFHLDFIRKEGV
M9MM93_DANRE/17-99------------------------------------KDYHKYGLIGAC....GDADQEDFIVQFDDEQLAHVDFKEQKDV
Q6MGB1_RAT/29-108------------------------------------EHVATY.DIFVQ....TQHPSGECMYAFDGDEQFYVDLDREETV
G1L546_AILME/37-114------------------------------------PRVSV..CLVVQ....THRPSGEYMFEFDGDEQFYVDLDK.ETV
G1PA08_MYOLU/2-81------------------------------------DHVSTY.AEFVQ....THSPSGEYMFQFDGDEQFYVDLDKKETV
L8Y815_TUPCH/29-108------------------------------------DHVSTY.LTFTQ....THRPSGEFMFQFDGDEMFYVDQDKRETI
L8Y3F3_TUPCH/29-108------------------------------------DHVSTY.LAFTQ....THRPSGEYMSQLDGDEVFYVDQDKRETI
L8YBX0_TUPCH/29-108------------------------------------DHVSIY.LMFAQ....TQRPSGEYMFQIDGDEQFYVDQDKKETI
I3M2H3_SPETR/44-123------------------------------------DHVISF.AMFAQ....TNAPTGEFMYEFDEDEMFYVDRDKKETI
G5BB02_HETGA/33-112------------------------------------DHVSTY.AIFAQ....THSPSGEYMFEFDEDEQFYVDLDKKETI
HA2P_RABIT/1-80------------------------------------EHVSVF.VIFAQ....THEPSGECMFEFDEDEVFHVDLDKKQAI
G3TMW3_LOXAF/41-120------------------------------------DHVSTF.AMFTQ....THVPSGEYMFEFDEDEMFSVNLDKKETV
H0VMA0_CAVPO/42-122------------------------------------DHVSTY.AEFVQ....RSRPSGEFIFDIDEDEMFYVDLDSRQTV
H0UYJ7_CAVPO/26-105------------------------------------DHVSRY.AEFVQ....TQTPSGEYMFELDEDEQFYVDLDKRQTV
G1R500_NOMLE/35-114------------------------------------DHVSTY.AAFVQ....THRPTGEFMFEFDEDEQFYVDLDKKETV
H0WUA6_OTOGA/41-120------------------------------------DHVSTY.FEFVQ....THRPSGEYMFEFDEDEMFYVDLDKKETV
H2RBA7_PANTR/29-109------------------------------------DHVASYGVNFYQ....SHGPSGQYTHEFDGDEEFYVDLETKETV
W5Q1M3_SHEEP/29-109------------------------------------DHIAAYGINVYH....SYGPSGYYTHEFDGDEEFYVDLEKRETV
G7P2R3_MACFA/2-81------------------------------------DHVASYGVNLYQ....SYGFSGQYSHEFDGDEQFYVDLERKETV
F7GQ21_MACMU/12-91------------------------------------DHLASYGVNFYQ....SYGLSGQYSHEFDGDEQFYVDLGRKETV
G3RX38_GORGO/29-109------------------------------------DHVASCGVNLYQ....SYGPSGQFTHEFDGDEQFYVDLERKETA
F7I518_CALJA/33-113------------------------------------DHVASYGVNLYQ....SYGPSGQFTHEFDGDEEFYVDLGKKETV
H0VR34_CAVPO/30-110------------------------------------DHVAAYGINVYQ....SYGSSGYYTHEFDGDELYYVDLEKRQTV
G5BB12_HETGA/29-109------------------------------------DHVASYGVNVYQ....SYGPSGQYTHEFDGDEQFYVDLKKKETI
W5Q2C6_SHEEP/29-109------------------------------------DHVGSYGISIYQ....SYGPSGQYTHEFDGDEQFYVDLEKKETV
M3Y3I6_MUSPF/29-109------------------------------------DHAASYGINVYQ....SYGPSAQYTHEFDGDEEFYVDLEKKETV
G1QAF8_MYOLU/29-109------------------------------------DHIAAYGVCFSQ....SYSPSGQYTHEFDGDEEFYVDLEKRETV
G1Q5X0_MYOLU/29-109------------------------------------DHVGAYGIHVYQ....SYGPSGQYTHEFDGDEEFYVDLDKEETV
L7N114_MYOLU/30-110------------------------------------DHVRAYGINVYP....YYGSSGQYTHESDGDEEFYVDLDKKETV
G1PGE2_MYOLU/3-83------------------------------------DHVGAYGINVYQ....SYGPSGQYTHEFDGDEEFYVDLDKKETV
I3MDX2_SPETR/29-109------------------------------------DHVANYGINLYQ....SYGPSGQYTHEFDGDEEFYVDLQKKQTV
L5KYV0_PTEAL/29-109------------------------------------DHVASYGINVYQ....SYGPSGQYTHEFDGDEEFYVNLEKQETV
F6YG75_HORSE/29-109------------------------------------DHFASYGTVIYE....SYGDFGQYTHEFDGDEEFHVDLEKKETV
F7D2Z8_MONDO/30-110------------------------------------DHVGTYGTTMAQ....SYGPSGQYTMECDEDEIFYVDQQKKETV
G1P5L8_MYOLU/30-110------------------------------------DHVGNFGPCFSQ....SYGSSGQYTFEFDGEEIFYVDQNKRETV
G1Q9G7_MYOLU/3-83------------------------------------DHIIACGISVSQ....SYGPSGQYTFEFDGDEIFYVDPKKKKTV
G1QA26_MYOLU/29-109------------------------------------DHVAAYGASFYQ....SYGPSGQYTFEFDGDEMFYVDLEKKETV
G3UHX0_LOXAF/29-109------------------------------------DHVGCYGTTIYQ....SYGPGGQYTQEFDGDELFYVNLEKKETV
O97981_PIG/29-109------------------------------------DHMGSYGPAFYQ....SYDGSGQFTYDFDGEQLFSVDLKKREAV
G3HQS4_CRIGR/268-348------------------------------------DHMGSYGPAFYQ....SYDASGQFTHEFDGEQIFSVDLKNGEVV
K7EUP3_PONAB/29-109------------------------------------DHVGSYGPAFYQ....SYGASGQFTHEFDGEQLFSVDLKKSEAV
G1QBV7_MYOLU/2-82------------------------------------DHVGTYGTNVYQ....TYGASGQFTYEFDGDELFYVDLKTRETV
I3N7K0_SPETR/29-108------------------------------------DHVGTYGTNIYQ....TYGDYGQFTYEFDKDELFYLDMGKKETV
I3MR31_SPETR/27-107------------------------------------DHVGTYGRNIYQ....TYGDYGQFTYEFDGDELFYVDLEKKETV
F6T370_MONDO/29-109------------------------------------DHVGTFGTTVYH....SYGPSGQNTNDFDEDELFYVDLKKKETV
F1ML44_BOVIN/29-109------------------------------------DHVGSYGTEIYQ....SHGPSGQYTQEFDGDELFYVDLGKKETV
H0WYE3_OTOGA/29-109------------------------------------DHVGIYGLNVYQ....SYGSSGQYTQEFDGDEMFYVDLERKETV
HA2B_RAT/30-110------------------------------------DHVGSYGITVYQ....YHESKGQYTHEFDGDERFYVDLDKKETI
HA2B_MOUSE/30-110------------------------------------DHVGTYGISVYQ....SPGDIGQYTFEFDGDELFYVDLDKKETV
F6ZJJ9_HORSE/29-109------------------------------------DHIGSYGITMYE....SSGPSGQYNFEFDGDETFYVDLEKKETI
F7D2J1_XENTR/21-100------------------------------------DYF.DYSALFYQ....TRRPTGEYLFDYNGNELFHVDLDSKSVV
F6ZD60_MONDO/30-109------------------------------------NHVIIQ.AEFAQ....TSNPEGEFMFDFDGDEIFHVDMDKRETV
A7X5M6_ORNAN/29-108------------------------------------EHRIIQ.AEFSQ....THSPTGEFMFEFDGDEIFHVDLDRKETV
G3UHG4_LOXAF/2-81------------------------------------EHVTTH.TELYL....SPNQSGEFMLDFDGDEIFHVNMEKKETA
G3UJA6_LOXAF/27-104------------------------------------EHVTIQ.AEFYL......SPSAEFMLDFDGDEFFYVNMEQKETV
G5C3I9_HETGA/21-100------------------------------------EHKIIQ.AEFYL....SPDETGEFMFDFDGDEIFHVDVKKEQTV
HA22_MOUSE/29-108------------------------------------EHTIIQ.AEFYL....LPDKRGEFMFDFDGDEIFHVDIEKSETI
G1L6J1_AILME/29-108------------------------------------DHVIIQ.AEFYM....TPDPSGEYMFDFDGDEIFHVDLEKKETV
U3IBP5_ANAPL/28-111------------------------------------GHVLMQ.TEFYQRDETRNKEGGQFMFDFDGDEIFHVDLEKSETI
H2ZTM7_LATCH/28-107------------------------------------EHTLFQ.IDFCQ....TGHPNGDYNFLFDEDEAFSVDLEEKEAV
H2ZYC5_LATCH/4-83------------------------------------EHTLSQ.TGFCQ....TGHPNGDYNFMLDNEEAFSVDLEEKETV
F6S093_HUMAN/8-85------------------------------------NHTFLH.TVYCQ....DGSPSVGLSEAYDEDQLFFFDFSQNTRV
G5BB05_HETGA/92-169------------------------------------NHTFRH.TVFCQ....EGTPSIGLSESYDEDLLFSFDFSKNTRV
I3MD72_SPETR/41-118------------------------------------NHTFRH.TVFCQ....DGSPSIGLTETYDEDLLFSFDFSRNTRV
G3U806_LOXAF/37-114------------------------------------NHTFLH.TMYCQ....NGTPSLGLSEAYDEDQLFSFDFSQNSRV
G3HQS6_CRIGR/42-118------------------------------------NHTFRH.TVFCQ....DGNPSIGLSESYDEDQLF.YDFSQNTRV
Q31621_MOUSE/41-118------------------------------------NHTFRH.TLFCQ....DGIPNIGLSETYDEDELFSFDFSQNTRV
K7GRZ3_PIG/40-117------------------------------------NHTFQY.TMYCQ....DGNPEVGLSEVYDGDQLFSFNFSQNIRV
M3XS77_MUSPF/41-118------------------------------------NHTFQH.TMYCQ....NWNPSIGLSEAYDGDQLFSFDFSQNTRV
W5PDP1_SHEEP/41-118------------------------------------NHTLLH.TVYCQ....DWSPSVGLSEAYDGDQLFSFDFSQNIRV
W5MK71_LEPOC/37-117------------------------------------TYEVAYFCQ.......SENRKGSRNEVFDDDEMFHIDPDRKVDE
W5MKC8_LEPOC/20-100------------------------------------IDINVIGCK.......SDDPVAQDEAQLDGDEMFYADFDKKEMI

PF00129

HLAH_HUMAN/25-203WTAADMA-----AQ-ITKRKWEAARRAEQ.RRVYLEGEFVEWLRRYLENGKETL--
ZA2G_HUMAN/26-201WVPFDPA-----AQ-ITKQKWEAEPVYVQRAKAYLEEECPATLRKYLKYSKNIL--
HA10_MOUSE/25-203WTAADVA-----AI-ITRRKWEQAGAAEY.YRAYLEAECVEWLLRYLELGKETL--
HA15_MOUSE/21-199WTANDIA-----SQ-ISKHKSEAVDEAHQ.QRAYLQGPCVEWLHRYLRLGNETL--
1C01_GORGO/25-203WTAADTA-----AQ-ITQRKWEAARWAER.QRAYLEGLCVEWLRRYLENGKETL--
FCGRN_RAT/25-198WSGEWPE-----TD-IVGNLWMKQPEAARKESEFLLTSCPERLLGHLERGRQNL--
HA12_MOUSE/25-203WTAADMA-----AQ-ITRRKWEQAGAAER.DRAYLEGECVEWLRRYLKNGNATL--
HA1F_CHICK/23-198FTAAVPE-----AV-PTKRKWEEESEPER.WKNYLEETCVEWLRRYVEYGKAEL--
HA17_MOUSE/22-200WTAVDMA-----AQ-ITRRKWEQAGIAEK.DQAYLEGTCMQSLRRYLQLGKETL--
HA11_RAT/25-203WAVADFA-----AW-ITRSKWQRNGAAER.SRAYLEGTCVEWLLRYLERGKETL--
HA1A_BOVIN/22-200WTAGETE-----AQ-ITKRKWEAAGYAEV.QRNYLEGECVEWLRRYLENGKDTL--
HLAG_HUMAN/25-203WTAADTA-----AQ-ISKRKCEAANVAEQ.RRAYLEGTCVEWLHRYLENGKEML--
HA1A_RABIT/25-203WTAADTA-----AQ-NTQRKWEAAGEAER.HRAYLERECVEWLRRYLEMGKETL--
HLAE_HUMAN/22-200WTAVDTA-----AQ-ISEQKSNDASEAEH.QRAYLEDTCVEWLHKYLEKGKETL--
HA1T_MOUSE/27-205WTAADTA-----AE-ITRSKWEQAGYTEL.RRTYLEGPCKDSLLRYLENRKKTQ--
1C28_PANTR/22-200WTAADTV-----AQ-ITQRFYEAEEYAEE.FRTYLEGECLELLRRYLENGKETL--
HA19_CANFA/25-204WTAADTA-----AQ-ITQRKWEAAGVAELQWRNYLETTCVEWLRRYLEMGKETL--

PF16497

G7NW87_MACFA/1-198WEPAQEAP--LWVN-LAIQVLNQDKWTKETVQWLLNDTCPQFVSGLLESGKSE---
F6RUT0_HORSE/1-198WVPAPDTP--QWVA-RVIEVLNDDQGTREMVQSLLNDTCPQFVRGLLETGKSE---
L7N1C3_MYOLU/1-197WVPAPDAP--HGTE-MISNVLNKDQYIKDTLEWLLNDICPQLVTGLLEAGQQD---
F6QYN3_HORSE/1-198WLPSPDGG--SRAQ-HACELYNGDKVGLEITDRFLSDTCPRLLLSLLDAGKAD---
CD1D1_MOUSE/1-200WQTVPGAP--SWLD-LPIKVLNADQGTSATVQMLLNDTCPLFVRGLLEAGKSD---
F7DC15_HORSE/1-198WLPSPKGG--NRAQ-HVCQLFNWDQITLEIIQRLLSDTCPRFLLGLLDAGKSD---
CD1D_SHEEP/1-198WVSAPDAP--PWSQ-VVCKVLNEDQGTKETVHWLLHDICPELVKGLMQTGKSE---
I3MFM6_SPETR/1-196WEPAPQAP--QWVD-LVIKVLNQNQGTKETVQWLLNDICPQFVNGLLETGKSE---
G1PVC0_MYOLU/1-198WLPSPKGG--TRAQ-DMCRRFNQYLVVKNVVQRILSDTCPRFLLSIPEAGKAD---
L7N1K8_MYOLU/1-198WLPSPKGG--TRAQ-DMCKLYNQYVVITNIVQRILSDTCPRFLLSILDAGKAD---
H0WFT3_OTOGA/1-199WEPAPQVP--DWGN-WVIGELNKDQGTRETVQWLLSDICPQLAGALLEAGASE---
F7BW69_HORSE/1-198WLPSPKGG--SRAQ-QVSGRFNLNKVFLETWHRLLTDTCPRFLLGLLDAGKAD---
G1QBJ7_MYOLU/1-198WLPSSKGG--TRAQ-EVCRLFNQRHVVNIIIQRLLRDTCPRFLLGLFDAGKAD---
M3YN29_MUSPF/1-198WWPSPKGG--SRAQ-EVCKRFNQYHVLNEEIHTFFSDTCPKFLLGLLDAGKAD---
F1PZ60_CANFA/1-198WWPSPKGG--RRAQ-QVCKLLNQYHVVNLRIHSHISDFCPHYLLGLLDAGKAD---
G1L1W7_AILME/2-199WWPSPEGG--SRAQ-QVCRLFNQDHEDNELMHKLITDHCPRYLSSLLDAGKAD---
G3HKH3_CRIGR/1-198FQKAPDAP--PWTE-LAIKVLNTDQGTRETIQQLLNDTCPQVLYGLLEAGKAE---
G1LFS0_AILME/1-198WWPSPKGG--SRAQ-QVCRLFNQYHEDNELIQALIIDYCPRYLSSLLDAGKAD---
A0ZPR3_PIG/1-198WLPSPKGG--TRAQ-LVCKLFNLYQGTLEIIHKLLSDTCPRFVLGLLDAGKAD---

PF14586

RAE1C_MOUSE/31-204WRSANDE-----SG-VIMNKWNDDGDLVQRLKYFIPE-CRQKIDEFLKQSKEK---

PF00969

DRB3_HUMAN/42-116YRAVTELG.....R-PVAESWNSQKDLLEQKRGRVDNYCRHNYGVGE---------
DRB4_HUMAN/42-116YQAVTELG.....R-PDAEYWNSQKDLLERRRAEVDTYCRYNYGVVE---------
HB2D_CANFA/42-116FRAVTELG.....R-PVAESWNGQKEILEQERATVDTYCRHNYGVIE---------
HB2A_RAT/8-82FRALTELG.....R-SWADDWNSQKEILEQKRAEMDTVCRYNYEETE---------
DOB_HUMAN/39-113FVALTKLG.....Q-PDAEQWNSRLDLLERSRQAVDGVCRHNYRLGA---------
DQB2_HUMAN/45-118FQAVTELG.....R-.SIEDWNNYKDFLEQERAAVDKVCRHNYEAEL---------
DPB1_HUMAN/42-114FRAVTELG.....R-PAAEYWNSQKDILEEKRAVPDRMCRHNYELGG---------
HB2L_CHICK/8-82FVADTVLG.....E-PSAKLFNSQPDVLEKNRAAVEMLCNYNYEIVA---------
HB2D_RAT/40-114FRAVTELG.....R-PSAEYYNKQKEYMEQLRATVDTACKHDYEISE---------
HB2C_PIG/45-119FRAVTPLG.....R-PEADSWNSQKDVLEQMRAEVDRVCKHNYQIEE---------
HB2A_MOUSE/40-114HRAVTELG.....R-PDAEYWNSQPEILERTRAELDTVCRHNYEGPE---------
HB21_MOUSE/40-114FHAVTELG.....R-PDAENWNSQPEFLEQKRAEVDTVCRHNYEISD---------
DMB_HUMAN/27-106MAPCEFGVLNSLAN-VLSQHLNQKDTLMQRLRNGLQNCATHTQPFWG---------
O35424_MOUSE/39-113FVALTELG.....E-PDADQWNKRLDLLETSRAAVNMVCRQKYKLGA---------
HB2P_RABIT/43-113FRAVSELG.....R-QVAESWN..LEYLQQARAEVDRVCRHNYELFQ---------
F1N610_BOVIN/47-117YRALTPLG.....R-PAAEYWNSQKDILEQTRAEADTVCRHNYQA..---------
F1NSZ6_CHICK/40-113HVADTPLG.....E-PQAEYWNSNAEILENRMNEVDTYCRHNYGVVE---------
M3WAZ6_FELCA/46-118YRAVTELG.....R-PDAKYWNGLKDYMEETRTAVDWFCRHNYGVF.---------
M3XET4_FELCA/43-114FRAVSELG.....R-PDAKYWNGQKDFMERKHAEVDTVCRHNYGV..---------
Q1MTC8_DANRE/29-104FVGYTEQG.....L-IFAENFNKDQAYLHQLKAQVDTFCRHNAQIWD---------
Q31099_MOUSE/27-106IVPCEFGVLSRLAE-IISNILNEQESLIHRLQNGLQDCATHTQPFWD---------
Q3UUV9_MOUSE/43-114FLAVTELG.....R-PIVEYLNTQKDMLDNYRASVDR.CRNNYDLV.---------
Q58DW7_BOVIN/27-105MIPREFGVLNGLAR-YLSQFLNNNSYLIQRLSNGLQNCAAHTQPFW.---------
Q6MGA7_RAT/27-106IVPCEYGVLFKLAE-FISNILNKEEGLIQRLKNGLQDCSTHTQPFWN---------
Q70IB5_BOVIN/44-114FVAVTELG.....R-VCAEIWNTQKDLLAEFRAYVDTLCRHNYK...---------
W5PC43_SHEEP/40-111FVALTELG.....K-PDAELWNNRPDILARSRASVDMLCRRNYKL..---------
W5Q266_SHEEP/32-102FTALTELG.....R-PDAEYWNQQKDFMEQMRAKVDTVCRSNYQ...---------

PF00993

G3N564_GASAC/36-114RPLPSFVD--.PIE.FPGGAYEQAVTDLQI........CRSNLKTHVKGLKDVPLE
G3N551_GASAC/28-106RPQPSFVD--.PID.YREGTYETAVGNQQI........CRNNLKIDLKAFKDFPLE
H2L2T1_ORYLA/33-110GPQLPLGG--.HFI.NPDG.YQFAKVYEQV........CRRNLKALKKTTKGLQLE
H2MYR3_ORYLA/32-109DAQPSFVG--.HIT.Y.AGGYGATVLELQG........CRNDLEVIRRFTKDLPLK
M4A196_XIPMA/25-103DPQPPFVV--.HTS.YREGVYEQAVANQQV........CRSNLKVCRSAMKDIPDE
H2MXB6_ORYLA/22-99EPQPPFVD--.HVS.Y.PGGYEQAVANQQI........CRSNLKISRIAMKDLPLE
M4AFZ0_XIPMA/29-106DTLPDFVS--.HPS.F.SGLYEQSVGQQQL........CKNNLKIIRTGLKDIPDP
I3KVG9_ORENI/23-101DAPPDFIG--.SFN.YQEGAYENAVANQQI........CRANLKVDSKGMKDFPLE
I3KVH2_ORENI/23-100YPQPPFID--.PIT.V.PGGYESSVAFQHS........CRENMKLFGKGMKDYPPE
I3J7S9_ORENI/23-101YPLPPFID--.PIT.YGEDAYESSVAFQKT........CRKNMKQFGEGMKDFPPE
I3JXB4_ORENI/24-101YILPPFAE--.PMI.Y.PGAYKQAVTELKV........CRHNLKALRAVMKDYPSN
I3JKK1_ORENI/23-101SPQPSFID--.PIS.FGAGAYKTAVSNLNT........CRQNLQITREGIKDFPPL
H2RPE2_TAKRU/21-98DGTPPFID--.PVR.F.EGFYSTAVTNLQI........CKSNMDVVRKGNKDMPPE
H2SD42_TAKRU/22-100DINPPFID--.PIT.YEEGAYSSAVADLQT........CKTSLDITRKSLKDMPPE
H2V674_TAKRU/22-96YGTPPFID--.PFR.....PTAAAVADLQT........CKYNLDVDRKGNKDMPTE
H3CDM2_TETNG/23-101YALPDFVD--.PLK.FPEGTYSQAVADQQI........CKINLGISRKGNKDMPRE
H3CJ64_TETNG/21-98YAQPDFID--.PIK.Y.EGFYSTAVAVLQI........CKFNLGIFRKGYKDMPRE
I3KVG1_ORENI/88-165NSLPPFAD--.LIT..CPGCYEQAVANQQV........CKQNLQTLRKMMKDYPLE
Q8WM94_DANRE/23-100ETLPDFGD--.PMT.F.PGFYEGSEGEMAV........CKSNLALRIKGFKSPPPE
F1R0K2_DANRE/23-100ITLPDFAD--.RIG.F.PGFYEISVDSIAG........CRRNLANNIRGFKSPPPA
F1QYA3_DANRE/32-109ATLPEFAD--.PLS.F.PGAYEESVADQEV........CKQNLATSIKAYNSPPEE
F1QNN0_DANRE/23-100KTTPSFAQ--YAVI...PDIYERALAFLDF........CKYDLHAYIKYFNNPPPE
W5LNP0_ASTMX/25-104VSLPKFAT--LNYT.IIPAAYEHSIQELQI........CRYNLKYSVFWYNFPAED
W5KCR1_ASTMX/22-100MTLPQFAD--.PAS.YGEGAYEGALSQVEN........CKSNLGIIKKVYNNPAEP
Q1MTC7_DANRE/23-100ATAPDFAD--.PLS.F.PGFYEAGVAQMEV........CKQNLATDIRAYNSPQEQ
M9MM93_DANRE/17-99ITLPEFAG--...........QAVLPPIYVDAKRAEFNCKAYLAVLREVYASSPEV
Q6MGB1_RAT/29-108WDLPEFSK--.VYA.FDA...QEALPYIDS........LKNNLRALIQRYNVTQDP
G1L546_AILME/37-114WQLPEFIH--.AFD.FDA...WRRVADIVT........ARKDLNILIQGSNHTRAT
G1PA08_MYOLU/2-81WRLPEFIH--.TFD.YDA...RRGIADIVM........ARKNLDTLIQRSNHTRAT
L8Y815_TUPCH/29-108WSLEEFGR--.VYS.YEV...QGGLQNLAV........AKGNLNTLMQCSNHTQAS
L8Y3F3_TUPCH/29-108WSLEEFGH--.AFS.FDA...QGALQNFAV........VKSYLNVLTQRSNHTQAS
L8YBX0_TUPCH/29-108WSLEEFGR--.AFS.FEA...QGGLQNIAI........VKGNLNIMMQRSNHTPAS
I3M2H3_SPETR/44-123WQLSEFGR--.GLS.FDS...QGGLTNIAI........AKSNLDIMTENSNHTQAA
G5BB02_HETGA/33-112WHLPEFGR--.AFS.FDA...QGGLTNIAI........ANSNLNILIKRTNRTQAP
HA2P_RABIT/1-80WYLPEFGR--.MFS.VEA...QGGLANIAA........AKSNLNACIQHSNHTQAP
G3TMW3_LOXAF/41-120WHLPEFGK--.AIY.FDA...EAGLSYMAR........MESNLKYGIQHLNYTQAT
H0VMA0_CAVPO/42-122WRLLEFGQ--.ALSPLDA...QAALTNIAI........LRNNLNIMIQRSNHTQAP
H0UYJ7_CAVPO/26-105WRLPEFGQ--.AFA.FDA...QGGLANIAI........MRTNLNFAIQDSNHTQAP
G1R500_NOMLE/35-114WHLEEFGR--.AFS.FEA...QGGLANIAI........LNNNLNIMIQRSNHTQAA
H0WUA6_OTOGA/41-120WHLPLFAQ--.AFS.FEA...QGGLANIAI........MKDNLNIMIRHSNHSQDT
H2RBA7_PANTR/29-109WQLPMFSK--.FIS.FDP...QSALRNMAV........GKHTLEFMIKQSNSTAAT
W5Q1M3_SHEEP/29-109WHLPVFSQ--.FRS.FDP...QGALRNMAS........GKQTLEIMIQRSNSTAAT
G7P2R3_MACFA/2-81WRLPVLSQ--.F.S.FDA...QFALTNIAV........GKQNLNYLMKQSNSTAAT
F7GQ21_MACMU/12-91WRLPIPYR--.Y.G.FDP...QFALRNIAV........LTHNLNVLIKRSNSTAAT
G3RX38_GORGO/29-109WRWPEFSK--.FGG.FDP...QGALRNMAV........AKHNLNIMIKRYNSTAAT
F7I518_CALJA/33-113WRLPVFST--.FTS.FDP...QGALTNIAT........MKPGLDILIKRSNCTAAT
H0VR34_CAVPO/30-110FWMPGLKK--.VVG.FDP...QGALNNIAI........VKNNLNILTKQSNSTAAT
G5BB12_HETGA/29-109FWLPGLNK--.VAG.FDP...QGALNNIAI........GKHNLDIITQHSNSTAAT
W5Q2C6_SHEEP/29-109WQLPLFSR--.MLS.FDP...QGALRNIAV........MKLHVDFLTKFSNSTAAT
M3Y3I6_MUSPF/29-109WQLPMFQT--.LGS.FDP...QGALRNLAV........SKQNLNILTKRSNYTAAT
G1QAF8_MYOLU/29-109WQLPMFSE--.VRG.FDP...QSGLTTVAT........ARYNLDLLIKSSNSTAAI
G1Q5X0_MYOLU/29-109WRLPMFSE--.VTN.FDP...QAGLREVAT........ARYNLDLLIRRSNSTAAI
L7N114_MYOLU/30-110WQLPMFSE--.FRN.FDP...QVALRNMAI........ANYTLGILIKSSNSTAAP
G1PGE2_MYOLU/3-83CWLLGFSE--.FKY.FDI...QTALINMAI........FKYNLDLLIKRSNYTAAP
I3MDX2_SPETR/29-109WTLPIFSQ--.MRK.FDP...QRALQNINI........LRHNLDILIKCSNSSEAP
L5KYV0_PTEAL/29-109WRLPEFGE--.FTS.FDP...QGALRNIAI........GKHNLDIMIKRSNSTAAP
F6YG75_HORSE/29-109WRLPEFGE--.FAT.FDP...QGGLRNVAT........AKHNLDIWIKRSNSTAAT
F7D2Z8_MONDO/30-110WRLPEFSH--.FAG.YDP...QGGLRNIDV........MEHNLDILIKRSNRTRAI
G1P5L8_MYOLU/30-110WRLPGLSE--.FGG.FDP...QGGLRNIAT........MNHNLDIMIKHSNYTAAI
G1Q9G7_MYOLU/3-83WRLPGLSE--.FGG.FDP...QSGLRNMAV........VNHTLDILIKSSNSTAAP
G1QA26_MYOLU/29-109WRLPGLSE--.FGG.FDP...QGGLRNMAT........AEYNLDILIKRSNSTAAI
G3UHX0_LOXAF/29-109WRLPMFSK--.FAG.FDP...QGGLRNIAV........LKHNLDILIKLSNSTAAT
O97981_PIG/29-109WRLPEFSN--.FAD.FDP...QNGLRGIAL........IRAHLDVLVERSNHTRAT
G3HQS4_CRIGR/268-348WRLPEFGD--.TQY.SNF...QSGLASIAM........IRAHLDILVERSNRTRAI
K7EUP3_PONAB/29-109WRLPEFGD--.FAR.FDP...QGGLAGIAA........IKAHLDILVERSNRSRAI
G1QBV7_MYOLU/2-82WRLPEFSN--.FTK.FET...QNALQNIVV........AKRNLDTLIKDSNFTPAT
I3N7K0_SPETR/29-108WRQPEFSN--.FIT.IEL...Q.ALRNLVV........VKNILDILIKNSNFTPAT
I3MR31_SPETR/27-107WRQPEFSN--.FAT.FEI...Q.GLRNLVV.......VKKKNLDTLIKDSNFTPAT
F6T370_MONDO/29-109WRKSEFCN--.FAK.FDP...QGGLRNFAM........MKNILDLLLRESNYTAAT
F1ML44_BOVIN/29-109WRLPMFSQ--.FAG.FDP...QAALSEIAT........AKHNLDVLTKRSNFTPVI
H0WYE3_OTOGA/29-109WRLPEFST--.FAG.FDP...QGGLREIAT........AKHNMETLTKRSNSTAAP
HA2B_RAT/30-110WRIPEFGQ--.LIS.FDP...QGALRNIAI........IKHNLEILMKRSNSTPAV
HA2B_MOUSE/30-110WMLPEFGQ--.LAS.FDP...QGGLQNIAV........VKHNLGVLTKRSNSTPAT
F6ZJJ9_HORSE/29-109WRLPEFSK--.FSS.FDP...QGALETIAI........IKEHLDVMMKRSNSTPAT
F7D2J1_XENTR/21-100WTLPGLSE--.HES.FDP...QGALQDINV........ARYNLDIGIKRSNSTAAT
F6ZD60_MONDO/30-109WRLTDFSN--.FAS.FEA...QGALANLAV........DKANLEIMMKRSNNTPDT
A7X5M6_ORNAN/29-108WRLADFSN--.YAS.FEA...QGGLANLAV........DKANMDILIKRSNHTPAT
G3UHG4_LOXAF/2-81WWLKGFEC--.FAS.FEA...QSALANIAV........DKANLDVMMKCFNCTPNI
G3UJA6_LOXAF/27-104WWLKEFEH--.FAS.FEA...QRVLASIAV........DKVNLDVVMKRSNHTPNI
G5C3I9_HETGA/21-100WRLEEFGR--.YAS.FEA...QGALANLAV........DKANLGIITKRSNNTPDA
HA22_MOUSE/29-108WRLEEFAK--.FAS.FEA...QGALANIAV........DKANLDVMKERSNNTPDA
G1L6J1_AILME/29-108WRLEEFGR--.FAS.FEA...QGALANIAV........DKANLDIMIKRSNHTPNT
U3IBP5_ANAPL/28-111WRLPIFTT--.FTS.FEA...QGALQNIAV........DKQNMEIMMKRSNRSQGT
H2ZTM7_LATCH/28-107WRLPQFKD--.LTR.YEV...EVAVANMRT........CESNLDIIIKTANESLTD
H2ZYC5_LATCH/4-83WRLPQFKD--.LAQ.VQA...ARALENMQV........CKTNLDIIKKAVNKTLAD
F6S093_HUMAN/8-85PRLPEFAD--WAQE.......QGDAPAILF........DKEFCEWMIQQIGPKLDG
G5BB05_HETGA/92-169PRLPDFAD--WAQD.......QSDAPAIAF........DKQFCEMMVQQLDPVLDG
I3MD72_SPETR/41-118PRLPEFAD--WAQD.......QRDASAIVF........DKGFCEAMIEKIGPQLEG
G3U806_LOXAF/37-114PRLPEFAD--WAKD.......QGDVSAISF........DKEFCQSMIQDIGPQFDG
G3HQS6_CRIGR/42-118PRLPDFAD--WAQE.......QGDASAISF........DKEFCNMLIQEIGPQLEG
Q31621_MOUSE/41-118PRLPDFAE--WAQG.......QGDASAIAF........DKSFCEMLMREVSPKLEG
K7GRZ3_PIG/40-117PRLPEFAD--WAHQ.......IEDTPAIFF........DKGFCREMIEKVGPLFEG
M3XS77_MUSPF/41-118PRLPEFAD--WAQK.......PGDTSTIFF........DKTFCQSMIQEIGPHLEG
W5PDP1_SHEEP/41-118PRLPEFAD--WAHQ.......HGDTSNIMF........DKGFCRTMIEEIGPQLEG
W5MK71_LEPOC/37-117PRLPEFEK--.WAW.NDSSLIQGALANLGI........CENHLKGVMKAIPDEPAV
W5MKC8_LEPOC/20-100LTLPAFAD--.SFG.VDPGWVQGAIANRQI........CINNLEVAIKAENNPPEN

This alignment is coloured according to the ClustalX colouring scheme:

 
Glycine (G)
 
Proline (P)
 
Small or hydrophobic (C,A,V,L,I,M,F,W)
 
Hydroxyl or amine amino acids (S,T,N,Q)
 
Charged amino-acids (D,E,R,K)
 
Histidine or tyrosine (H,Y)

For UniProt-based alignments, we also add some additional mark-up to the alignments where appropriate. Active site information is shown as follows:

 
Active site (residue annotated in SwissProt as an active site)
 
Predicted active site (residue aligns in a Pfam alignment with a SwissProt active site)
 
Predicted active site (residue annotated in SwissProt as a potential active site)

Some UniProt sequences can be mapped to protein structures, in which case we also show the secondary structure definition. These lines are shown below the sequence to which they apply and are marked (SS). The meaning of each of the symbols is as follows:

C
Random coil
H
Alpha-helix
G
3(10) helix
I
Pi-helix
E
Hydrogen bonded beta-strand (extended strand)
B
Residue in isolated beta-bridge
T
H-bonded turn (3-turn, 4-turn, or 5-turn)
S
Bend (five-residue bend centered at residue i)
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