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12  structures 311  species 5  interactions 482  sequences 5  architectures

Clan: bBprotInhib (CL0354)


beta-Barrel protease inhibitors Add an annotation

Superfamily consists of both metalloprotease- inhibitors and staphostatins.

This clan contains 3 families and the total number of domains in the clan is 482. The clan was built by P Coggill.


This clan contains the following 3 member families:

Inh Staphostatin_A Staphostatin_B

External database links

Domain organisation

Below is a listing of the unique domain organisations or architectures from this clan. More...

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The table below shows the number of occurrences of each domain throughout the sequence database. More...

Pfam family Num. domains Alignment
Inh (PF02974) 477 (99.0%) View
Staphostatin_A (PF09022) 3 (0.6%) View
Staphostatin_B (PF09023) 2 (0.4%) View
Total: 3 Total: 482 Clan alignment

Please note: Clan alignments can be very large and can cause problems for some browsers. Read the note above before viewing.

Family relationships

This diagram shows the relationships between members of this clan. More...

Species distribution

Tree controls


This tree shows the occurrence of the domains in this clan across different species. More...



There are 5 interactions for this clan. More...

Interacting families
Peptidase_C47 Staphostatin_B
Peptidase_M10 Inh
Peptidase_M10_C Inh
Reprolysin_2 Inh
Staphostatin_B Staphostatin_B


For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between the Pfam families in this clan, the corresponding UniProt entries, and the region of the three-dimensional structures that are available for that sequence.

Loading structure mapping...