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42  structures 17769  species 4  interactions 46562  sequences 61  architectures

Clan: Leu-IlvD (CL0364)


LeuD/IlvD-like Add an annotation

Superfamily includes LeuD-like, IlvD/EDD C-terminal domain-like, and AF0055-like families.

This clan contains 3 families and the total number of domains in the clan is 46562. The clan was built by A Bateman.


This clan contains the following 3 member families:

Aconitase_2_N Aconitase_C DUF126

External database links

Domain organisation

Below is a listing of the unique domain organisations or architectures from this clan. More...

Loading domain graphics...


The table below shows the number of occurrences of each domain throughout the sequence database. More...

Pfam family Num. domains Alignment
Aconitase_C (PF00694) 39400 (84.6%) View
Aconitase_2_N (PF06434) 6295 (13.5%) View
DUF126 (PF01989) 867 (1.9%) View
Total: 3 Total: 46562 Clan alignment

Please note: Clan alignments can be very large and can cause problems for some browsers. Read the note above before viewing.

Family relationships

This diagram shows the relationships between members of this clan. More...

Species distribution

Tree controls


This tree shows the occurrence of the domains in this clan across different species. More...



There are 4 interactions for this clan. More...

Interacting families
Aconitase Aconitase_C
Aconitase_2_N Aconitase
Aconitase_B_N Aconitase_2_N
Aconitase_C Aconitase_C


For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between the Pfam families in this clan, the corresponding UniProt entries, and the region of the three-dimensional structures that are available for that sequence.

Loading structure mapping...