Sequence alignment for CL0370

PF09252

D2XZ44_RAT/24-90CLPFFTAYGGVLSG--SKLWLNHELD-AYNATTGEREAYEKIQQCFR-EGGLKAKFLEPKILKAMVIS-----PEC
J3QK77_MOUSE/24-90CLPFFEGYASVLSG--SRVWLYQELQ-AFNATAEEKVALEKIQDCYS-EERIRNILLEPKIMEAMVAS-----PEC
M3Y7S1_MUSPF/24-90CPIFYSTFGALAIG--ERFPLDLNLD-VVGATEPEKEALEKIQDCYN-EKGLEAKGLDLIVMTTITTS-----NQC
Q8R1E9_MOUSE/24-90CAPFVGAYVKILGG--NRLALNAYLS-MFQATAAERVAFEKIQDCFN-EEPLTTKLKSPQIMMSILFS-----SEC
G1MEK7_AILME/24-90CPIFYIIFGSVAGG--SKSELDINLD-LVNATKPEKEALEKIQDCYN-EKGLKAKALDLDVMATITTS-----KQC
W5P379_SHEEP/24-90CPIFYGVFGTVSLG--SKTLLNATLD-LVAATDEEKAALGKIQDCYN-EAGLDGKFLDLLLMVSINLS-----TDC
G3MXE3_BOVIN/26-92CPVFYGGVAALLLG--SKTVLNSTLD-LVDSTDEEKAAFGKVQDCFN-EAGFDAKLKVVEIMGSIVFD-----KDC
G5E8B4_MOUSE/24-90CIPFFGVYLGILSG--NRIGLHTELA-PFDPTVEEKEAFEKIQDCYE-EEGLKAKTEDMKLMTTILFS-----SEC
FEL1B_FELCA/24-90CPIFYDVFFAVANG--NELLLDLSLT-KVNATEPERTAMKKIQDCYV-ENGLISRVLDGLVMTTISSS-----KDC
G1Q0Z5_MYOLU/24-90CPIFYGVFGTLAIG--SKTLLDASLE-LVHATQPEKVALEKIQECYN-EAGIESKILDLIVMGTITTS-----KEC
D2XZ38_MOUSE/25-91CASFFGVYLSTVSG--KRLWLHHELS-YFNPTDGETKSFKKIQDCYE-EAGLKAKSQDVQFMASMFFS-----SEC
E2QUP2_CANFA/24-90CPLFYSVFGTLAIG--KELPLNTALR-LANATEAEKAAMGKIQDCYN-EKGLDAKILDLIVMTTITTS-----KKC
S2B24_MOUSE/24-90CVPFFAGYAGVISG--SRLWLYHELS-AFNGTPKETVAYEKIQDCYK-EQGVKSQTLEPQILASILVT-----PEC
H0VV13_CAVPO/24-90CVSFYDVFGKVVLG--LKKPLFDALN-VVNATEAEKAAFGKIQDCFN-EGGLKVKILDTKALLKITSS-----KEC
G3N380_BOVIN/26-92CPVFYGALGTIFIG--SKTLLNSTFD-LVDATDEEKEAIGKLQDCFN-ENGLPAKLFIIELVSSIIIN-----KDC
Q8JZX1_MOUSE/24-90CLSFARTYGAILTL--RRTFLHGDLS-QFYATVAERVAFEKIQDCFR-EEGQKTIILNPQIMLSLYLS-----PEC
F1LSA5_RAT/24-87CFPFFGLYLGTVSG--SKLWLQHELS-YFNPTPGETDAYEKIQNCFN-EAGSLGKFRDIKVMCQVLKN-----...
G3VIU1_SARHA/24-90CLPFYITFGTVALR--NSVLLKLDLI-KYGATQEEYEAFRKIQECYA-EHPIIRTAMDIKLMTMTTIN-----KEC

PF01099

SG1D_BOVIN/24-88CPTFAADLTEFFYF..PDLLYRLSLA.KYNAPPEAVAAKMEVKQCTD.RFSVKNRLIITNILGKILL.......NC
H0UZ61_CAVPO/24-90CLSLTKDIVAFLTW..SDFAFELSIK.KYQAPEEVVASMMEVKQCVN.KIDSKYRGIILKVLVKVEKE.....PSC
I3MES7_SPETR/24-90CPEFFHIMETLFMG..TLSSYESSVE.PFNPDPDMKEAGIQMKKLLD.TLPVGIKMNVLKLSDKILKS.....PRC
G1SDB8_RABIT/24-89CPTFIAESTANLLA..SESVFRASLS.KYGAPPEAVEAKLQVKRCTD.KMSLGKRVLFGKVLGEIVLR......TC
G1QAY2_MYOLU/27-94CPAVKKDVTIFLTG..TPEEYVAQVE.KYQNNSLILANARKLKDCIDQKLTEEDKEHAVTVLNKIYSS.....PLC
SG2A1_HUMAN/22-90CKLLEDMVEKTINSDISIPEYKELLQ.EFIDSDAAAEAMGKFKQCFL.NQSHRTLKNFGLMMHTVYDS.....IWC
Q91WB5_MOUSE/25-92CPALQRKVDLFLNG..TTEEYVEYLK.QFNENTKVLENAANIKKCSDRTLTEEDKAQATSLINKITAS.....RTC
H2PUP9_PONAB/5-69CQALGSEITGFLLA..GKPVFKSQLA.KFKAPLEAVAAKMEVKKCVD.KMAYEKRVLITKTLGKIAE.......KC
L5LB72_MYODS/31-96CELLEEVIYKTIDPTESTTQYIDDLQ.PLIPGEVTEKALTNLKQCFL.DQDQETLNLVSEMMVMAVTS........
F7BLD6_ORNAN/28-91.EFFLDFLQTLLVGS.LKELYEGPLS.HFKINAAAKRAMAELKSCID.HLEPQNKAELVKLLSEVMGS........
SG1C1_RAT/27-92.EFFMEFLQTLLVGT.PEELYEGPLG.KYNVNDMAKAALTELKSCID.ELQPVHKEQLVKLLVQVLDA.....QE.
J3KMP9_MOUSE/24-92CGILDNIINGTISSSVSEDKYLEMVK.PYILLPSTRSAVKEFKQCFL.SQTEDTLSNVGLMMEIIFNS.....EEC
F6TBN3_ORNAN/24-87CDSFRELVTDYAFS..EPEVYYSHLN.PFNPTEEAQDAMVTIKRAAD.SLTYAQKKEANDVMQKVFAT........
F1RPX3_PIG/24-90CPSFVEVIQNLFKG..TLASYQASVE.PFSPNEDMKKAGAQLKTLVD.TLSPEAKDSVLKLQEKIIKS.....PLC
J9JHR2_CANFA/22-90CLLLEEAINKAIDSQVSIDEYQNFLQ.PFTYGLETNEAIAELKQCFL.QQSDETRSNFALMMDIIINS.....LSC
SC2B2_HUMAN/27-91IDKLLANVVFDV....SQDLLKEELA.RYNPSPLTEESFLNVQQCFA.NVSVTERFAHSVVIKKILQS.....NDC
G9KMK8_MUSPF/24-90CPAFLNVMKTLFVG..TLSSYEAALE.FFAPDADMRDGMIQLRNLVD.TLPSNTTQNILKFTGKVLKT.....PAC
SG2A2_RAT/23-91CSILDEVIRGTINSTVTLHDYMKLVK.PYVQDHFTEKAVKQFKQCFL.DQTDKTLENVGVMMEAIFNS.....ESC
M3WAC4_FELCA/24-90CQSFLNVMETLFTG..TLSSYEAAVE.PFLPDADMKDAGIQLKRLVD.TLPQKAKEGILKLTDKIIRS.....PLC
H0VSI6_CAVPO/28-92.EFFMEFLQVLLVGS.PEELYEGPLG.KYNVNQDAKEALTELKSCID.GLQPIHKAELVKLLEQVLSS.....E..
W5PHG2_SHEEP/29-92..LFMDFLQTLLVGS.TEELYEGPLS.KYNINADAKAAIAELKSCID.GLQPMHKAELVKLLVQVLGS.....Q..
H2RFA8_PANTR/24-88CPAVASEITVFLFL..SDAAINLQVA.KLNPPPEALAAKLEVKHCTD.QISFKKRLLIEKVLVEIVK.......KC
J3QJY4_MOUSE/26-93CPAIKEDVRLFLNG..TSEEYVEYVK.QYKDDPEILENTAKIKQCVDSTLTEEDKAHATAFIEKIEAS.....PLC
Q9GK63_RABIT/22-90CVLLESVVEKTIDPSVSVEEYKADLQ.RFIDTEQTEAAVEEFKECFL.SQSNETLANFRVMVHTIYDS.....LYC
G5E7C8_LOXAF/24-88CPSLLEEETAFLLA..GPLTYKLLIE.SYRPPSDVVEAKLQLKQCID.QLSFRNRLRVMNILEKIVL.......KC
F6UF44_HORSE/25-92CPAVKEDVNIFLTG..TPDDYVKKVS.QYQRNPVILANAEKLKNCIDKKLTAEDKENALSVLEKIYSS.....DFC
I3N9F3_SPETR/25-92CPAVKKDVEIFMKG..TLEEYVAYVS.RFQSNPLVLNNAKILKQCIDAKLTEEDKDLVLSGLDKVYAS.....DLC
D2XZ41_RAT/25-92CPVIEKDVGLFLFG..TPEEYVDYVA.EYEDDPEVLESTESIKQCVDSTLTDEDKQNAAAVIEKVKAN.....PLC
H0X9W9_OTOGA/22-90CQLLEDVINKTINPAVSMPEYKSVLY.EFTNGETDNEAVEEFKECFL.NQSNETLENIGILMQIIYGS.....KFC
F6SYQ8_HORSE/24-88CPSLVVDHTAMYFT..PDEFYKISLS.KYKAPAEAVWGMMQVKQCTD.EISIVDRFRIANALVTLSS.......LC
F7HZA5_CALJA/22-88CPLLEEMFSKTIDAEASKTEYKVFLQ.GFIDHNTTGNAADELKQGLL.NSSDKTLANIEVFMESRHGS.....S..
L7N1F3_MYOLU/22-90CESLEEVINKTIDPTESKTEYIKDLQ.RFIPSEFTANALKKIKQCFL.DQDEETLNNVMEMMAAIYNS.....RQC
E2QUN9_CANFA/25-92CPAVRDDVSLFLTG..STEDYVDNVA.RYQSSPVILENAKLLKECVDGKMTDGDKQNALSVLDKIYAS.....DLC
E2R0A4_CANFA/24-89CQNFLNVIKALFLD..TPSSYQAALE.FFNPDADMKDAMIQLKSLVD.TLPSNTTENILKFTEAVIKS.....PE.
G1QTG9_NOMLE/24-90CPSFLRVIETLFMD..TPSSYEAAME.LFSPDQDMREAGAQLKKLVD.TLPQKARESIIKLMEKIVQS.....SLC
F7HX05_CALJA/24-88CPDLDSQITHFLFS..SEASIKSEVV.KFGASPEAVAAKLTVKKCTD.QIAIEKRLVFENILGRIVA.......KC
W5P3B2_SHEEP/26-93CPALRDIVDLFISG..SHEAYIEQVE.KYNQNPDVLETADTLKSCVDENLTPQDKQDALSALNKIYSS.....SLC
F6SN30_HORSE/22-90CSVYKDLVDQTTDPTQSPAEYVAAFQ.EFITDNATAKAAMELKQCYL.NQSNETLANFDQMMQAIFES.....VWC
I3M7D7_SPETR/22-90CQLLEDAISKAINPEVTLEEYEVALQ.EFLHSDADRNAAEQFKQCFL.NQSNETLDNVRLMMKSIYDS.....TYC
G1U0C2_RABIT/25-92CPAVQEDVYVFLNG..SPEEYVSYVQ.NYQSDPLVLQNALALKQCVDGKLTAEDKGHAISAVNKIFSD.....PLC
A6QPK0_BOVIN/23-91CSLLDNVVEKSVDPTVSKDEYRAYLK.DFAQTDVEKKAADELKQCFL.QQSNETLANFKQMLQIIYDS.....IYC
F7HWY9_CALJA/24-86CPALLSEISGFFFI..SEPVFKLKLA.KYDAPPEAVAAILEMKKCPD.QMALEKRLLLEEVQLKIVA.........
G1T9Y9_RABIT/24-88CPAFATELTGFLLA..SDVLFRLQIE.KFNAPAEAVEAKMNVKRCVD.ELSLGKLLLIDKYWGHVLA.......KC
D6C4M6_SHEEP/24-90CPSLLYALGNLLIG..TPSSYEAALE.PFSPDEDMKEATRQLKELID.TLSPKAKDSVLQLMGKIVQS.....PEC
UTER_RABIT/24-90CPRFAHVIENLLLG..TPSSYETSLK.EFEPDDTMKDAGMQMKKVLD.SLPQTTRENIMKLTEKIVKS.....PLC
L9JSA1_TUPCH/24-85CPDLITKVENFLLS..SNDKFTPQLS.TYDVPLTSVEATLEVKKCTD.KLSHGERLRLVSILVITF..........
UTER_HORSE/24-90CQSFADIIQGLFLG..TPASFEAAVE.PFKPDADMKAATTQLKTLVD.FLPKNTKDSILKLMDKIAKS.....PLC
H0VWI6_CAVPO/22-90CQLLEDVITKTIERNVTVAQYKEFLQ.PYLDDKPSEHAAEELKQCFL.SQSDETLANVQQLMNIIYNS.....IFC
G3X7J8_BOVIN/25-92CPAVREDVYLFVRG..TPEEYIAKVK.EYNTNSAIVANARRLKDRVDEKLTEEDKQNAFSVLNKIYSS.....SLC
G1SNE0_RABIT/24-92CVILESVLDKTIDPSVSVEDYTTYLQ.KYILTDAAKVALEELKQCFL.SQSNETLANVKVLEYAVFDS.....LYC
F7HX10_CALJA/24-88CPAVISDITSFLFL..NDNLVKLEVG.KYNPPPEAVAAKLKIKKCTD.QISPGKRVLLEGVLASIVI.......EC
Q863D2_PIG/22-90CSYLERVISDTSDSSVTTDVYLASLQ.EYISSDDTTQAIKELRECFL.KQSEETLENFSVFMQVTYNS.....KLC
F1RPW6_PIG/24-89CRALVKEFSAFLWK..PDEIYKPELE.LFGAPPEAVDAKMKVKQCAN.GISFKKKILLTKTLVEILVK......KC
M3X6R4_FELCA/25-92CPAVKRDVDLFLMG..TPDKYVEQVA.QYNARPVVLANARNLKNCVDAKMTEEDKENALSVLDKIYTS.....PLC
L8Y501_TUPCH/22-85CAYLEGVIKDIANPTISIEQFKNSLK.EYIKDDATSNAVGEFKQCFL.NQSNETLENFVAFMVILI..........
SG2A2_HUMAN/22-90CPLLENVISKTINPQVSKTEYKELLQ.EFIDDNATTNAIDELKECFL.NQTDETLSNVEVFMQLIYDS.....SLC
SG1D2_HUMAN/24-88CPALVSELLDFFFI..SEPLFKLSLA.KFDAPPEAVAAKLGVKRCTD.QMSLQKRSLIAEVLVKILK.......KC
M3Y7T1_MUSPF/25-92CSSVKHDVTLFIKG..TPDEYVQQVA.QYRNETIILENARSLKECVDAKFTEDDRTNAINVLNKIYSS.....PLC
G3V9B4_RAT/25-92CPAMQTKVDLLLHG..TVDDYVAYVE.QYKDNPAILANAESIKQCVDSKLTKEDKDHATSLVEKIKAS.....PLC
F6PJZ2_ORNAN/24-90CPAFQKILSDYLES..PIDVLLENFA.PYEPSDNALEAVRALKQNSD.VFTAAERKSVGETLGIYSAS.....TVC
Q9GK67_RABIT/24-88CPAFVLDSVGFLFD..PKPVYRQKLA.KYDAPPEAVEAKLQVKECTD.EIDKGKRVLIAAVLTKIVK.......EC
SG3A2_MOUSE/30-98VDKLPVPLDDIIPSFDPLKMLLKTLG......ISVEHLVTGLKKCVD.ELGPEASEAVKKLLVIIICSYFPGRSLC
M3YRE6_MUSPF/27-89...FVNVSKGFLFQ..DAASFKTTIQGKFNPPQGVIEDYLEVKKCTD.QISAGNRKRLGEALGKIVL.......SC
F7HWX5_CALJA/24-88CPALLSETLGFLFV..DEPAFKLQLA.KFNAPPKAVAAKLEVKKCTD.QMSLEKRGPIEVALLKIME.......KC
G3VBG2_SARHA/34-101CPAVSEDVYAFING..TSKEYTDIVK.KHTENPAIIENAKILKACVDAKLTKEDKDAAVNLVTKIINY.....KFC
F6WF42_HORSE/22-90CQLLEDVVEKTITAELSPAEYVEAVQ.EFIPDEATEKAAIQLKQCYL.KQSNETLNDFRTMMNSMYNS.....AYC
G3TH86_LOXAF/24-88CPSVVAESTTFLVG..NPYDFKLLLE.SYDPPSEVVQAKLELKKCTD.EMSLESRQLIVNTLEKIMM.......KC
G7PPU8_MACFA/24-88CPALASEITGFLFL..SDDLLKLQVA.KFIPPPEALAAKLQVKHCTD.QIPLSDRLHIEKALPIITS.......SS
W5PZD0_SHEEP/24-88CPIFALDLKEYFYS..PDPLYKLSLA.KYIAPQEAVAAKMQVKQCTN.EFSVQNRLLITKILGKILV.......KC
F7G0A2_ORNAN/22-85CPDFQNIIDDYLGY..STDVLLAKLA.PYEPSDNALEAVRALKDTSD.AFTVAERKSVGETLLKRLKE........
F7HX07_CALJA/22-90CQLLEEVVDKTHDPEVSVPEYKQYLQ.EFIHGDESAEAVGEFKQCFL.KQSNETLQDFQVLMQKIYDS.....IYC
F6YRI9_ORNAN/26-92CPVFLDIVNKLFTG..TFREYLQSLQ.PYHPTEAMIEAVSELKGLVN.LLSPEHKATVLQLMGNIVFS.....KEC
J9P839_CANFA/60-128CLFLEQVVNKTIDSQVSIDEYQNFLQ.PFTSDLETKEAIAELKQCFL.QQSDETLSNFALMMNKIYNS.....YWC
PSC2_RAT/28-92CQALQDVTITFLLN..PEEELKRELE.EFDAPPEAVEANLKVKRCIN.KIMYGDRLSMGTSLVFIML.......KC
G3VLI6_SARHA/35-97CLTFPQVAEILIKG..TAQKYLESIQ.CFQPDEAMEAAGKLLKEQVD.VLSNATKMDIMRLMGKILT.........
G1TL67_RABIT/22-90CPFVEKMVKTTLNSNVSTAEYIDVLK.HYINDERTELAVVEFKNCFL.SQSEETLRNVVEMMETIYNS.....KLC
F7HWY7_CALJA/22-90CPLVEEVISKTIDPEVSKTEYKEFLQ.EFIDNDVTANAIDELKQCFL.NQSDETLDSVGVLMQAIYDS.....RFC
M0R9A3_RAT/28-89CDAVLRESAAFVLG..SKENLRKELE.QYSVPAEAVKAKLEVKRCVD.QMRYGDRLKVAGALVQIL..........
F6SVD9_HORSE/24-88CSSLATHISAFLFT..IDPVYKLQLQ.KYMAPSKAVEAKLQVKTCMN.EISHGNKLLIAKILGRVLL.......KC
J9P7B6_CANFA/24-89CPSLGKDMIAFLFQ..HEALYKPHLQLAYNPPEAALNAKLQVKSCTD.KIPIVQRKLIAGVLEKILM.......KC
M3YRD7_MUSPF/26-94CPLVEEVVNKTIDSQVSVDEYQTFMK.PFSNDPITDKAIAQLKECFL.TQSDETLSKVGEMMDIIYKS.....EWC
M3YRD4_MUSPF/24-88CPDLATDMTGFLLQ..EKNMYEKTLE.KYNAPPEFIEAKMQVKACTD.EMSLMSRMLIEKALGKILL.......KC
L7N1B8_MYOLU/22-90CQRLEDMIDSTIDPSVTEDQYIESLE.EFIPGDTTAQLLREFRHCFL.DQSNRTLSNVQVMMAAIYNS.....RQC
M3X5D6_FELCA/22-87CLLLEQAVNKTISPEVSVSEYQNFLQ.DFVQETEEEKALADVKQCFL.NQSNETLHNFAQMMVITVSS........
PSC1_RAT/27-91CELVAHETISFLMK..SEEELKKELE.MYNAPPAAVEAKLEVKRCVD.QMSNGDRLVVAETLVYIFL.......EC
L7N195_MYOLU/22-90CTSLEDVISKSIDPTESKTQYIEDLQ.QLIPREFTANALKKIKQCFL.DLNNETLSNFRVMMDAIFNS.....RQC
A2BH64_MOUSE/25-92CPVLQKKVHKFFDG..TTEEYVEYLK.QYNNDPLVLENAANIKKCSDRMLAEEDKTQATNFINKVTGS.....RSC
O35176_MOUSE/26-93CPAIKEDVHLFLFG..TPEEYVNYVE.KYKDDPETLENTEKLKICVDRTLTKENKEHAAAFIEKIESS.....PLC
J3QNG2_MOUSE/9-77CIILDNVFKSTIDSSVSKNDYLKLVS.PDEHGPFIKNAMKQFKQCLL.DQSKETLANVQEMMDAIFNS.....DSC
H0VVI1_CAVPO/24-90CPSFHQVLHNFLVG..TLSSYQSMVE.PFKPDADMQEAGTVMKNLVD.SLPQSTREKVLKLSEKIVTT.....KVC
UTER_MOUSE/24-90CPGFLQVLEALLME..SESGYVASLK.PFNPGSDLQNAGTQLKRLVD.TLPQETRINIMKLTEKILTS.....PLC
Q9GK65_RABIT/24-88CPALLAENFGYLYF..NKDVFRLQLA.KFMPPREAAEALLTVKKCTD.GMPEFKRNLIAGALGEVVL.......QC
G3U8F5_LOXAF/24-90CRSFLRVIELLFKG..TLSSFEDAVS.PFNPDLDMIDASIQMKKSVD.KLPQNAKDSLMRLTERIVRS.....PQC
Q9GK62_RABIT/22-90CQLLDDMVTKTLDSQISLTDYHNFFK.NLSSGAAAEMAVKDFKQCFL.MQSNETLNNIKVFLETVYNS.....PFC
G3W621_SARHA/28-90.EFFLEFLQTLLAGS.LEDLYEGPLA.PYDINPATKAAMAELKSCID.NLAPVNKAELVKLLVGVLS.........
M3YRE3_MUSPF/22-91CPLLEEMVNKTIDPRVSMDEYQNLVRPYYIPFTDSEEAMGQLKQCFL.SQSNETLSNAAKLPNMIYES.....KWC
G3I076_CRIGR/23-85CNAMDNLIAQTIDGNVTLEEYHEVVK.SYTAFPYDETAVEKFKQCFN.DQSEETLTNFAVMEVII...........
F6RVI6_HORSE/22-90CQLLEDVVEKTLDPELSTTEYVEALQ.EFISDDAAREVAAQFKQCFL.IQSNETLSNFGKMMETMYNS.....LYC

This alignment is coloured according to the ClustalX colouring scheme:

 
Glycine (G)
 
Proline (P)
 
Small or hydrophobic (C,A,V,L,I,M,F,W)
 
Hydroxyl or amine amino acids (S,T,N,Q)
 
Charged amino-acids (D,E,R,K)
 
Histidine or tyrosine (H,Y)

For UniProt-based alignments, we also add some additional mark-up to the alignments where appropriate. Active site information is shown as follows:

 
Active site (residue annotated in SwissProt as an active site)
 
Predicted active site (residue aligns in a Pfam alignment with a SwissProt active site)
 
Predicted active site (residue annotated in SwissProt as a potential active site)

Some UniProt sequences can be mapped to protein structures, in which case we also show the secondary structure definition. These lines are shown below the sequence to which they apply and are marked (SS). The meaning of each of the symbols is as follows:

C
Random coil
H
Alpha-helix
G
3(10) helix
I
Pi-helix
E
Hydrogen bonded beta-strand (extended strand)
B
Residue in isolated beta-bridge
T
H-bonded turn (3-turn, 4-turn, or 5-turn)
S
Bend (five-residue bend centered at residue i)
Close window