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12  structures 9224  species 0  interactions 13471  sequences 98  architectures

Clan: Oxa1 (CL0376)


Cytochrome oxidase biogenesis family Add an annotation

The cytochrome oxidase biogenesis families are membrane transporters akin to the E coli protein YidC. For those proteins whose N-termini must reside in the intermembrane space, export is mediated by the Oxa1p export machinery, machinery that depends upon the membrane potential. Qxa1p homologues are found in all living organisms. TCDB:2.A.9.

This clan contains 2 families and the total number of domains in the clan is 13471. The clan was built by A Bateman.


This clan contains the following 2 member families:


Domain organisation

Below is a listing of the unique domain organisations or architectures from this clan. More...

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The table below shows the number of occurrences of each domain throughout the sequence database. More...

Pfam family Num. domains Alignment
60KD_IMP (PF02096) 11364 (84.4%) View
EMC3_TMCO1 (PF01956) 2107 (15.6%) View
Total: 2 Total: 13471 Clan alignment

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Family relationships

This diagram shows the relationships between members of this clan. More...

Species distribution

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This tree shows the occurrence of the domains in this clan across different species. More...



For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between the Pfam families in this clan, the corresponding UniProt entries, and the region of the three-dimensional structures that are available for that sequence.

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