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41  structures 19214  species 6  interactions 36315  sequences 54  architectures

Clan: PheT-TilS (CL0383)


Phenylalanine- and lysidine-tRNA synthetase domain superfamily Add an annotation

Families here are thought to contain a putative tRNA-binding structural motif. The families are the C-terminal domains of tRNA-Ile-lysidine and the phenylalanine-tRNA synthetases.

This clan contains 2 families and the total number of domains in the clan is 36315. The clan was built by P Coggill.


This clan contains the following 2 member families:

B3_4 TilS_C

External database links

Domain organisation

Below is a listing of the unique domain organisations or architectures from this clan. More...

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The table below shows the number of occurrences of each domain throughout the sequence database. More...

Pfam family Num. domains Alignment
B3_4 (PF03483) 24043 (66.2%) View
TilS_C (PF11734) 12272 (33.8%) View
Total: 2 Total: 36315 Clan alignment

Please note: Clan alignments can be very large and can cause problems for some browsers. Read the note above before viewing.

Family relationships

This diagram shows the relationships between members of this clan. More...

Species distribution

Tree controls


This tree shows the occurrence of the domains in this clan across different species. More...



There are 6 interactions for this clan. More...

Interacting families
B3_4 B3_4
TilS TilS_C
tRNA-synt_2d B3_4
tRNA_bind B3_4


For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between the Pfam families in this clan, the corresponding UniProt entries, and the region of the three-dimensional structures that are available for that sequence.

Loading structure mapping...