Sequence alignment for CL0386

PF02876

SPEG_STRPQ/124-232L......QFV.GILNQDGKETYLP...SEVVRIKKKQFTLQEFDLKIRKFLM..EKYNIY...............DSESR
Q2YVR8_STAAB/137-232P......NLL.VKKIDDKDGFSI....DEFFFIQKEEVSLKELDFKIRKLLI..KKYKLY.................EGS
Q2G2Y0_STAA8/135-229H........LFVNKVYGGNLDAS....IDSFSINKEEVSLKELDFKIRQHLV..KNYGLY.................KGT
Q9RN33_STAAU/135-229H........LLVNKVDGGNLDAS....IDSFLIQKEEISLKELDFKIRQQLV..EKYGLY.................QGT
Q2FJL7_STAA3/255-352KKVNHKVELS.ITKKDNQGMISRD...VSEYMITKEEISLKELDFKLRKQLI..EKHNLY..................GN
Q9ZFS7_STAAU/82-170K..............DEKGKISHD...DSEYKITKEEISLKELDFKLRKQLI..EQHNLY..................GN
Q6GJP6_STAAR/240-341KKVDYKTGIS.ITKEDKKGTISHD...VSEYKITKEEISLKELDFKLRKQLI..EQHNLY..................GN
A5IPY0_STAA9/195-292HK....AGVR.ITKEDNKGTISHD...VSEFKITKEQISLKELDFKLRKQLI..ENHNLY..................GN
Q6GJN6_STAAR/146-232H.................NTATRQ...AETYRINKEEISLKELDFKLRKHLI..ENHELY.................KTE
Q6GHR9_STAAR/141-238K......HYKLNVTYKDKAGTFIG..EYQFYTGNKPVLTLKEVDFRIRQTLI..KNKKLY.................NGD
Q2FZB2_STAA8/141-238K......HYKLNVTYKDKAETFTG..GFPVYEGNKPVLTLKELDFRIRQTLI..KSKKLY.................NNS
Q76FM8_STREQ/124-232L......QFV.GILNQDGEETSLP...SYTILIKHKQFILQEFDFKIRKFLM..ETYSIY...............DSESR
Q99QN1_STRP1/123-230S......KIV.GNLLIDGVQQKTL...INPIKIDKPIFTIQEFDFKIRQYLM..QTYKIY...............DPNSP
Q9S1H9_STRPY/147-255L......KISLVIYGINRKQIPVP...YNQISPTKTTVTAQEIDLKARKFLI..SQHQLY...............SSGSN
SPEH_STRP1/132-236I......KVP.VNVWDKSKQQP.....PMFITVNKPKVTAQEVDIKVRKLLI..KKYDIY..............NNREQK
Q7A4K9_STAAN/118-238R......IIP.INLIINGKHQTVT...TKSVSTDKKMVTAQEIDVKLRKYLQ..DEFNIYGHNDTGKGKEYGTSSKFYSG
Q8NVM2_STAAW/116-237R......NIP.INIWINGNHKTIS...TNKVSTNKKFVTAQEIDIKLRRYLQ..EEYNIYGHNGTKKGEEYGHKSKFYSG
A6U2T1_STAA2/117-237R......KIP.INLWVNGKHKTIS...TDKIATNKKLVTAQEIDVKLRRYLQ..EEYNIYGHNNTGKGKEYGYKSKFYSG
Q93CC6_STAAU/117-237R......NIP.INLWVNGKQNTIS...TDKVSTQKKEVTAQEIDIKLRKYLQ..NEYNIYGFNKTKKGQEYGYQSKFNSG
Q99T47_STAAM/114-234R......RIP.INLWVNGEHQTIS...TDKVSTNKKLVTAQEIDTKLRRYLQ..EEYNIYGFNDTNKGRNYGNKSKFSSG
Q8VVW1_STRPY/101-221K......NIP.VNIFIDGVQQKYSYTDISTVSTDKKEVTIQELDVKSRYYLQ..KHFNIYGFGDVK...DFGRSSRFQSG
Q48SH7_STRPM/158-258K......AIY.INIFGEKELRTLT..AKDKITFKNNIVTLQEIDVRLRKSLMGDSKIKLY...............EYDSL
Q849U3_STRPY/122-222K......TIY.MNVFIDGHKKDDT..SKYKITFEKSPVTFQEVDVRLRKSFMLNDEIKLY...............QYDSK
Q79X14_STRPQ/152-258P......NIT.VKVYEDNENIL.....SFDITTNKKQVTVQELDCKTRKILV..SRKNLY..............EFNNSP
A0FI84_STAAU/145-250R......SIT.VRVFEDGKNLL.....SFDVQTNKKKVTAQELDYLTRHYLV..KNKKLY..............EFNNSP
Q06534_STAAU/129-235Q......NVL.IRVYENKRNTI.....SFEVQTDKKSVTAQELDIKARSFLI..NKKNLY..............EFNSSP
Q7A4X0_STAAN/28-134H......NIL.IKVYENERNSL.....SFDIPTNKKNITAQEIDYKVRNYLL..KHKNLY..............EFNSSP
Q2YUP5_STAAB/153-257Q......PIV.VKVYENDSVTL.....SFDINIDKETVTIQELDYKVRNKLI..SKINLY..............HLGGTS
Q764P6_STAIN/156-262Q......TIY.VKVFENSKHII.....TFEIQADKKLVTAQELDAKARKFLI..DKLNLY..............EFKGSP
ETXG_STAAU/149-256K......LIT.VQVTIDNRQSL.....GFTITTNKNMVTIQELDYKARHWLT..KEKKLY..............EFDGSA
Q76LS8_STAAU/150-257K......NII.VPVTVDNKQQF.....SFTISTNKKTVTVQELDYKVRNWLT..NNKKLY..............EFDGSA
Q2YTP3_STAAB/143-249K......VIG.VNVFKDGVQQE.....GFVIKTKKAKVTVQELDTKVRFKLE..NLYKIY..............NKDTGN
Q6GFM7_STAAR/147-253K......EIG.VAVYKDNVNVN.....TFIVTTDKKKVTAQELDIKVRTKLN..NVYKLY..............DRMTSD
ETXH_STAAU/132-236R......VIG.ANVWVDGIQKE.....TELIRTNKKNVTLQELDIKIRKILS..DKYKIY...............YKDSE
Q2FXX5_STAA8/127-232K......NIP.CNLWIDGHQTEIE...LTAVKTKKKIVTIQELEVQLRNYLN..EKYKLY...............EQGGD
Q6R2F9_STAAU/44-152K......KIP.INLWINGVQKEVS...LDKVQTDKKNVTVQELDAQARRYLQ..KDLKLYN............NDTLGGK
A1KWT9_STAAU/140-248K......NVP.INLWIDGAQKRVS...LDKVKTDKKTVTIQELDAQARYFLQ..GEYLLYH............NDSFGGK
O85217_STAAU/147-255K......KIP.INLWIDSIRTVVP...LDIVKTNKKKVTIQELDLQARYYLH..KQYNLYN............PSTFDGK
A5HJW3_STAAU/131-239K......KVP.INLWIDGKQNTVP...LGTVKTNKKEVTVQELDLQSRHYLH..ETYNLYN............TDAFNGK
Q6G7Y7_STAAS/147-255K......KVP.INLWLDGKQNTVP...LETVKTNKKNVTVQELDLQARRYLQ..EKYNLYN............SDVFDGK
ETXE_STAAU/147-255K......KVP.INLWIDGKQTTVP...IDKVKTSKKEVTVQELDLQARHYLH..GKFGLYN............SDSFGGK

PF03642

Q99VA9_STAAM/48-135--------VP-YTIAVDGIMAFNQ---SYLNLPKDSQLSYLDLGNKVKALLY--DERGVT--------------PEKIRN
Q9XAS5_STAAU/376-463--------VP-YTIAVNGASNPTL---SDLKFTGDSRVSYSDITKKVKSVLK--HDRGIN--------------DIELKF
Q9S2Z4_STAAU/374-461--------VP-YTIAVNGTSTPIL---SDLKFTGDPRVGYKDITKKVKSVLK--HDRGIG--------------ERELKY
Q99QS2_STAAM/11-98--------VK-FPVTINKFENIVS---NEFVFYNASKITINDLSIKLKSAMA--NDQGIT--------------KHDIGL
Q9XAS5_STAAU/489-576--------VK-FPVTINGFSNLVS---NEFAFLHPHKITTNDLNAKLRLALA--SDQGIT--------------KHDIGL
Q9Z4P5_STAAU/481-568--------VP-YTIAVNGTSTPIA---SKLRLSNKQLIGYQDLNKKVKSVLK--HDRGIN--------------DIELKF
Q99S64_STAAM/47-134--------VP-YTISVDGITALHR---TYFVFPENKKVLYQEIDSKVKNELA--SQRGVT--------------TEKINN
Q9Z4J2_STAAU/432-519--------VP-YTIAVNGTSTPIL---SKLKISNKQLISHKYLNDKVKSVLK--SERGIS--------------DLDLKF
Q9XAS5_STAAU/271-358--------VP-YSINLNGTTTNIQ---SNLAFSNKPWTNYKNLTTKVKSVLK--SDRGVS--------------ERDLKH
MAP1_STAAM/160-247--------VP-YTITVNGTSQNIL---SNLTFNKNQNISYKDLEGKVKSVLE--SNRGIT--------------DVDLRL

PF02876

SPEG_STRPQ/124-232YTSGSLFLATKD..SKHYEVDLFNKDDK.LLSRDSFFKRYKDNKIFNSEEISHFDIYLK
Q2YVR8_STAAB/137-232ADKGRIVINMKD..ENKYEIDL...........SDKLDFESMADVISSEQIKNIEVNLK
Q2G2Y0_STAA8/135-229TKYGKITINLKD..GEKQEIDL...........GDKLQFERMGDVLNSKDINKIEVTLK
Q9RN33_STAAU/135-229SKYGKITINLKD..EKREVIDL...........SDKLEFERMGDVLNSKDIKGISVTIN
Q2FJL7_STAA3/255-352MGSGTIVIKMKN..GGKYTFEL...........HKKLQEHRMA....GTNIDNIEVNIK
Q9ZFS7_STAAU/82-170IGSGTIVIKTKN..GGKYTFEL...........HKKLQEHRMADVIDGTSIERIEVNLK
Q6GJP6_STAAR/240-341IGSGTIVIKMKN..GGKYTFEL...........HKKLQQHRMADVIDGTNIDRIEVNLK
A5IPY0_STAA9/195-292VGSGKIVINMKN..GGKYTFEL...........HKKLQENRMADVIDGTNIDNIEVNIK
Q6GJN6_STAAR/146-232PKDGKIRITMKG..GGYYTFEL...........NKKLQPHRMGDVIDGRNIEKIEVDLY
Q6GHR9_STAAR/141-238YNKGHIKITGG...SNNYTIDL...........SKRLKSTDANRYVKNPQTAHIEILLE
Q2FZB2_STAA8/141-238YNKGQIKITGA...DNNYTIDL...........SKRLPSTDANRYVKKPQNAKIEVILE
Q76FM8_STREQ/124-232YISGSFFLATKD..SKHYEVDLFNKDDK.LLDRNRFFKRYRDNKVFNSEEISHFDIYLK
Q99QN1_STRP1/123-230YIKGQLEIAING..NKHESFNLYDATS..SSTRSDIFKKYKDNKTINMKDFSHFDIYLW
Q9S1H9_STRPY/147-255YKSGKLVVHTND.NSDKYSLDLFYTGY...RDKESIFKVYKDNKSFNIDKIGHLDIEID
SPEH_STRP1/132-236YSKGTVTLDLNS..GKDIVFDLYYFGN...GDFNSMLKIYSNNERIDSTQF.HVDVSIS
Q7A4K9_STAAN/118-238FDKGSVVFHMND..GSNFSYDLFYTGY...GLPESFLKIYKDNKTVDSTQF.HLDVEIS
Q8NVM2_STAAW/116-237FNIGKVTFHLNN..NDTFSYDLFYTGD..DGLPKSFLKIYEDNKTVESEKF.HLDVDIS
A6U2T1_STAA2/117-237FNNGKVLFHLNN..EKSFSYDLFYTGD...GLPVSFLKIYEDNKIIESEKF.HLDVEIS
Q93CC6_STAAU/117-237FNKGKITFHLNN..EPSFTYDLFYTGT...GQAESFLKIYDDNKTIDTENF.HLDVEIS
Q99T47_STAAM/114-234FNAGKILFHLND..GSSFSYDLFDTGT...GQAESFLKIYNDNKTVETEKF.HLDVEIS
Q8VVW1_STRPY/101-221FEEGNIIFHLNS..GERISYNLFDTGH...GDRESMLKKYSDNKTAYSDQL.HIDIYLV
Q48SH7_STRPM/158-258YKKGFWDIHYKD..GGIRHTNLFTYPD............YTDNETIDMSKVSHFDVHLN
Q849U3_STRPY/122-222VLSGNWEFHGSG..EKEEGADLFKYPD............YRYNNLIDIDKKSHIDVYLF
Q79X14_STRPQ/152-258YETGYIKFIESS..GDSFWYDMMPAPGA.IFDQSKYLMLYNDNKTVSSSAI.AIEVHLT
A0FI84_STAAU/145-250YETGYIKFIENE...NSFWYDMMPAPGD.KFDQSKYLMMYNDNKMVDSKDV.KIEVYLT
Q06534_STAAU/129-235YETGYIKFIENN..GNTFWYDMMPAPGD.KFDQSKYLMMYNDNKTVDSKSV.KIEVHLT
Q7A4X0_STAAN/28-134YETGYIKFIEGS..GHSFWYDLMPESGK.KFYPTKYLLIYNDNKTVESKSI.NVEVHLT
Q2YUP5_STAAB/153-257YETGYIKFIENG..NRYYWYDMMPDPG...FTQSKYLMIYRGNETVESAKT.EIEVHLT
Q764P6_STAIN/156-262YETGYIKFIEND..DKSFWYDLMPPPGN.NFNQSKYLTMYSDNKTVESEDI.KIEVHLT
ETXG_STAAU/149-256FESGYIKFTEKN..NTSFWFDLFPKKELVPFVPYKFLNIYGDNKVVDSKSI.KMEVFLN
Q76LS8_STAAU/150-257YETGYIKFIEQN..KDSFWYDLFPKKDLVPFIPYKFVNIYGDNKTIDASSV.KIEVHLT
Q2YTP3_STAAB/143-249IQKGCIFFHSHNHQDQSFYYDLYNIKG...SVGAEFFQFYSDNRTVSSSNY.HIDVFLY
Q6GFM7_STAAR/147-253VQKGYIKFHSHSEHKESFYYDLFYIKG...NLPDQYLQIYNDNKTIDSSDY.HIDVYLF
ETXH_STAAU/132-236ISKGLIEFDMKT..PRDYSFDIYDLKG...ENDYEIDKIYEDNKTLKSDDISHIDVNLY
Q2FXX5_STAA8/127-232IVKGYVKYYNDD..EQNVEYDFYNLNG...EYGREVLKMYADNKTINSDKL.HLDIYLF
Q6R2F9_STAAU/44-152IQRGKIEFDSSD..GSKVSYDLFDVKG...DFPEKQLRIYSDNKTLSTEHL.HIDIYLY
A1KWT9_STAAU/140-248IQKGFIEFHDAN..GFEVSYDLFDVKG...DYPDTQLRIYNDNKTISSKNL.HIDIYLF
O85217_STAAU/147-255IQKGLIVFHTSK..EPLVSYDLFNVIG...QYPDKLLKIYQDNKIIESENM.HIDIYLY
A5HJW3_STAAU/131-239IQRGLIGFHPSS..GDSVGYDLFGAQG...QYPDTQLRIYRDNKTIKSKNM.HIDIYLY
Q6G7Y7_STAAS/147-255VQRGLIVFHTST..EPSVNYDLFGAQG...QYSNTLLRIYRDNKTINSENM.HIDIYLY
ETXE_STAAU/147-255VQRGLIVFHSSE..GSTVSYDLFDAQG...QYPDTLLRIYRDNKTINSENL.HIDLYLY

PF03642

Q99VA9_STAAM/48-135AKSAVYTITWKD--GSKKEVDL--------------KKDSYTANLFDSNSIK-------
Q9XAS5_STAAU/376-463AKQAKYTIHFKN--GKTQVVDL--------------KSDIFTRNLFSVKDIK-------
Q9S2Z4_STAAU/374-461AKKATYTVHFKN--GKKKVINL--------------NSKISQLNLLYVQDIK-------
Q99QS2_STAAM/11-98AERAVYKVYFKN--GSSKYVDL--------------KTEYKDERVFKATDIK-------
Q9XAS5_STAAU/489-576SERTVYKVYFKD--GSSKFVDL--------------KAAKQDSKVFKATDIK-------
Q9Z4P5_STAAU/481-568AKQAKYTVHFKN--GKTQVVDL--------------KSDIFTRNLFSVKDIK-------
Q99S64_STAAM/47-134AQTATYTLTLND--GNKKVVNL--------------KKNDDAKNSIDPSTIK-------
Q9Z4J2_STAAU/432-519AKQAKYTVYFKN--GKKQVVNL--------------KSDIFTPNLFSAKDIK-------
Q9XAS5_STAAU/271-358AKKAYYTVYFKN--GGKRVIHL--------------NSNIYTANLVHAKDVK-------
MAP1_STAAM/160-247SKQAKYTVNFKN--GTKKVIDL--------------KSGIYTANLINSSDIK-------

This alignment is coloured according to the ClustalX colouring scheme:

 
Glycine (G)
 
Proline (P)
 
Small or hydrophobic (C,A,V,L,I,M,F,W)
 
Hydroxyl or amine amino acids (S,T,N,Q)
 
Charged amino-acids (D,E,R,K)
 
Histidine or tyrosine (H,Y)

For UniProt-based alignments, we also add some additional mark-up to the alignments where appropriate. Active site information is shown as follows:

 
Active site (residue annotated in SwissProt as an active site)
 
Predicted active site (residue aligns in a Pfam alignment with a SwissProt active site)
 
Predicted active site (residue annotated in SwissProt as a potential active site)

Some UniProt sequences can be mapped to protein structures, in which case we also show the secondary structure definition. These lines are shown below the sequence to which they apply and are marked (SS). The meaning of each of the symbols is as follows:

C
Random coil
H
Alpha-helix
G
3(10) helix
I
Pi-helix
E
Hydrogen bonded beta-strand (extended strand)
B
Residue in isolated beta-bridge
T
H-bonded turn (3-turn, 4-turn, or 5-turn)
S
Bend (five-residue bend centered at residue i)
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