Sequence alignment for CL0398

PF07522

Q296G1_DROPS/557-655PDLQSRL-NDDPYQANLHVI.GMG......KVT....YLVLAEYFKQFEDQ......YDMLLAIRPSG..WEKNSK....
Q9VND2_DROME/481-579PDLDSVL-TEDRSGANLHVI.AMG......KIS....YPSLVDYFTEFEDQ......YDMLLGIRPSG..WEKNS.....
Q16PI6_AEDAE/575-673PLQQQWL-VEDPKFADIHVL.SMN......KLS....YDELVSYVEQFPDR......YDLLIALRPSG..WEKNS.....
Q8RZQ7_ORYSJ/227-334SLIAPEI-ITEDPSCRFQIL.GFQ......NLY....DKACTKIEEARASL......QPEPLFIRPSTQWYAHCAQS...
Q7QDQ3_ANOGA/486-584SQQLSVL-VADPNKANIHVL.AMN......KLS....YDELNEYMNQFPDR......YESVIAIRPSG..WEKNS.....
A2EC29_TRIVA/231-334FAKPELF-SEDPYLTRIHLL.PIQ......ECG....KEKVSLYAASMG........FDSVTAIRPSG..WNGRPFWRCP
DCR1C_CHICK/239-345PEILYHI-TTD.RYTQIHAC.RHP......KDDDYVRGNRLPCGITCQNGT......PLHVISIKPSTMWFGERIKKTNV
PSO2_SCHPO/403-529QDLIDLL-TDDPTQASVHMV.TMM......GIH....PNSLLDYLEQYNSS......FDKIIGYKVTG..WTFQPL..EN
DCR1A_CHICK/844-950AAVNSLI-TMNWDGTLLHIL.PMM......QIN....FKGLQDHLNKFSEN......FDQVLAFKPTG..WTYSDSCLSV
A0A0D1CBW9_USTMA/699-829PELHSML-TRSPL.ASVHVT.NLH......AIN....GEALRDVVAALRTHG...HDFTHAVAFRPTG..WTYKPP..AG
Q6ZD68_ORYSJ/209-321SLVAPEI-LTDDSSSRFQVI.GFP......RLS....ERATEMLALARAKH......QPEPLIIRASSQWYAYYEPPEGS
Q4Q2L8_LEIMA/388-491EHLLSVF-LVPMASVGYRAVAALA......HADG.PAVMDMEDGLALNLDR......YDQVLMVEPTG..WSKRCVAREV
SNM1_ARATH/360-467DDISKNL-STDGKATCLHVL.PMS......SLK....VERLDEHLKIYREQ......YGAVLAFRPTG..WTYSEKIGEH
DCR1A_MOUSE/900-1006PEVSSLI-TTDMCDSLVHLL.PMM......QIN....FKGLQSHLKKCGGK......YDQILAFRPTG..WTHSNNITST
A6RF66_AJECN/673-802SELSALI-TNNPVEAQVHMV.TMM......DVH....TGTLLDYLHSLKPH......FSRVVGFRPTG..WSYRPPAGRM
Q8IK95_PLAF7/674-779KHILNKI-TDNKLEAQIHIV.DINYSYIFPKID....KRKFLNLIDEEIEK.....EFDSFYYIIPTG..WVKKFS....
Q8LQQ4_ORYSJ/223-351DDNQEIF-TTQTSLTRIRAV.PRY......SLT....IESLDALNT...........VCPTIGIMPSGIPWLWKNSKGKA
A2GFK2_TRIVA/225-328YCSESCF-TNDPTKTRVYLV.PIM......DCN....SVSASVWAKQNG........YSSVCAIAATG..WSGKAGWKNP
A7E8T1_SCLS1/835-964PELTSRL-TSDPREAQIHMQ.MLM......ELR....PETLQDYLTGYKPH......FTRVVGFRPSG..WSYKPPNSRF
DCR1C_DANRE/239-345PEILCHV-TTN.RATQIHAC.RHP......KDEEFFRANRLPCGSTAPDGI......PLNIISIKPSTIWFGERTRKTSV
A4S4B7_OSTLU/228-334PEERSAM-THDDSKTNLHVV.PMG......STS....FMKMASILKYYKSR......FDTVIAFRPTG..WTFSAQKKTA
Q4YJX0_PLABA/192-297KDMLNRI-TGNKLEAEIHIV.DINYSYIFPKIE....KNKLRSLIDAEMED.....EFDSFYYIIPTG..WVKNYY....
A7RZG8_NEMVE/216-320DFIQSVI-TTDKSEGRIHVL.PMG......KLN....HQHLSSYMDQFKGK......FTRVVAFKPTG..WEHKS...GP
DCR1C_HUMAN/239-345PEILHHL-TTD.RNTQIHAC.RHP......KAEEYFQWSKLPCGITSRNRI......PLHIISIKPSTMWFGERSRKTNV
DCR1_DICDI/481-582CLDINKF-TTNELITPFRAV.TMS......MLS....YHNMLSLLDSSNNK......YKRVIGFRPTG..WTQAKKSITY
Q6C9D1_YARLI/448-581PVISELL-TSDPLEAQVHLV.PLG......QTR....KDQLFEHLKSFKPH......FSKIVAFAPTG..WSYRPPKSAI
Q6CJP1_KLULA/366-495WFPEGLL-TTDHKSSNVHLV.AMH..............TDLDKYLSQLSNM......FDSIVVFRPTG..WTFSNQYDKS
Q6FR52_CANGA/556-712CFDNSLL-TDDPSESQIHLV.SLK......VLR...DFNAIDNYLKTIKELTGNKIKYDNVFGFIPTG..WTFGNRYKKD
C8VBT0_EMENI/673-800.ELSALL-TDDPLQAQVHMQ.TLF......EIR....AETLCDYLDSMKPH......FTRVIGFRPTG..WTYRPPAGRT
F4IDZ7_ARATH/235-347.....EI-VSEDPSSRFHIFSGFP......KLY....ERTSAKLAEARSKL......QSEPLIIRPSAQWYVCDDEDDWK
Q5KDG6_CRYNJ/644-773PELHSML-TSDPIEAQVHLL.PLG......NIQ....LDRLQSYLTLLHPH......FDRVLGFRPTG..WSYSPPAGTD
Q7XV88_ORYSJ/357-463.DLSKMI-CSDSQSSSLHVL.PLS......SLR....HENLQKYLETLKQR......FLAVLAFRPTG..WTFSEETGNQ

PF07521

Q7UMQ3_RHOBA/427-488RYDVRAK.THQLTGYSAHGD-----------------QEDLIALVEGMTDA-----------------------------
Q8IL83_PLAF7/431-493VVKRKCR.FEQIS.FSAHSD-----------------FNQTKTFIEKLKCP-----------------------------
E7LXW1_YEASV/359-428TIPRRCQ.VEEIS.FAAHVD-----------------FQENLEFIEKISAP-----------------------------
A3DMW0_STAMF/352-417DEPIKAR.LEWFD.LSSHAG-----------------KDGLISIIQRYKNT-----------------------------
Q4JB02_SULAC/555-622NIKVNME.IGVVEGFSGHSD-----------------RRQLLAFLRNLNVK-----------------------------
Q6AQL6_DESPS/455-518DYPLRAH.VVSLGGLSGHGD-----------------RDEMTRVLKDSNLN-----------------------------
A8ZYV1_DESOH/454-517EYPLKAR.VENIGGFSAHAD-----------------KHELMRFVKKSNLD-----------------------------
A6Q9T8_SULNB/395-458DIRIKAS.MYTINGFSAHAD-----------------QNGIIKWVKDIEDL-----------------------------
A1RXC5_THEPD/357-418RGPVKAR.IEWFD.FSAHCG-----------------HSELVKTLDSAKKG-----------------------------
A1U408_MARHV/381-445YWPVKAE.IHNLDSMSAHGD-----------------YQEILQWLEQGSLK-----------------------------
Q3AAG6_CARHZ/390-454EIAVKAE.VYHYDGLSAHAD-----------------QRELLAFIGRFSQK-----------------------------
A8BNK1_GIAIC/412-487YADAKMR.IEELS.FSAHSD-----------------YNQTLDVLRKTRPR-----------------------------
Q0W8H2_METAR/362-424IVKLRCQ.LEQYS.FSAHSG-----------------ESELKAIVKHMVDR-----------------------------
Q0W2D5_METAR/563-627IMKINLQ.VTTVDGFSGHSD-----------------RRQLMEYVKRMDPR-----------------------------
Q72BD6_DESVH/353-407DPRVSFHEIH....TSGHAF-----------------RQDLKRYANAINPK-----------------------------
Q8ZTD5_PYRAE/354-416TIKVEAR.LEWFD.FSAHAG-----------------RRELEEFVKRFTPE-----------------------------
A8ZWQ7_DESOH/346-410GADVVYEKISDIH.VSGHAF-----------------REELIEMMQMVNPT-----------------------------
Q92Z81_RHIME/392-456DIRVRAR.IRKLDIYSGHAD-----------------GSELADWVRARQPI-----------------------------
Q6MLH4_BDEBA/380-444YVEINCK.VIPSDSFSAHAD-----------------RSDLMTWLKQAPEI-----------------------------
Q74HX7_LACJO/274-324GIELITL......RCSGHAD-----------------VAELKEIIAGFEPK-----------------------------
A0JWK6_ARTS2/385-449DVRIRAE.VIQMESLSAHAD-----------------SDGLIEWMRAAARE-----------------------------
A1SFD7_NOCSJ/387-451YVPVRAE.IVDVPYFSVHAD-----------------ADDIVGWLGRAPEP-----------------------------
A8AB05_IGNH4/310-359PPELHLQ.......ISRHAT-----------------RQELLQFISLTKAK-----------------------------
A6TST8_ALKMQ/372-422NMDIIDL......HTSGHAH-----------------IDSLKKVIRSSGAK-----------------------------
A4CMY8_ROBBH/383-447YIRVAAG.IHHYESLSAHAD-----------------QEEILWWTAGMENQ-----------------------------
CPSF2_DICDI/550-612RLPINCK.IQTID.YEGCSD-----------------GRSIKAIIQQIAPT-----------------------------
O29718_ARCFU/337-399VVKLKMG.VEQYD.FSAHAD-----------------DRQLKEYVKRVVDR-----------------------------
Q6L0H4_PICTO/339-395TIKPSMK.IDFFD.LSAHAG-----------------HSDLVKFIKDIDPG-----------------------------
Q15V20_PSEA6/396-459DYVVKAQ.IETLGGFSAHAG-----------------QNELVEWVSHFENN-----------------------------
R7D7I2_9FIRM/392-456TVAVGAE.IRQMPGISGHAD-----------------VNGLMTWIKAFKEK-----------------------------
B3E8Q6_GEOLS/353-409KDEVRPGVRYVYAHTSGHAP-----------------VEDLQRLVKAVKPR-----------------------------
Q2S180_SALRD/394-456PQPVYCT.VERFR.FSGHSD-----------------RRELLSLVERMTPE-----------------------------
Q18IP5_HALWD/406-470EIHVPTEWIHEIGGMSAHAG-----------------ANDLLSFARQVNPQ-----------------------------
Q81SC3_BACAN/350-410RIGKECR.VKRVP.YKVHQS-----------------IRDVKEMLNTLLPE-----------------------------
A4S2Z0_OSTLU/352-408GPEIAMG.REDCLHSSGHGY-----------------KDELDEVIKLLKPE-----------------------------
Q6L180_PICTO/565-629KIDINMS.VETAEGFSGHSN-----------------KAQLLNYIATMQPK-----------------------------
Q9CF63_LACLA/350-413GGVMKML.ASDLK.ISGHAN-----------------ARDLQFLLDIFRPK-----------------------------
A2BK26_HYPBU/355-417EEPVRAR.VEWLD.FSSHAD-----------------RNGLLDVVRTTKPR-----------------------------
Q8U1V4_PYRFU/365-431KLRMKGVRMIKNLHVSGHAS-----------------KEDHRYLIRMLNPE-----------------------------
A0RY50_CENSY/347-409EMSVAAE.VKQFQ.FSGHSD-----------------RTELFEMIKSIKGD-----------------------------
A9A2U6_NITMS/573-637VVTINCG.VEKLDGFSGHSD-----------------YNQLMSFVQRLRPK-----------------------------
Q0ABE3_ALKEH/392-455TVRVGAQ.IHTVGGLSAHAD-----------------QRELMAWYEGFRDH-----------------------------
CPSF2_HUMAN/528-591SIEIKAR.VTYID.YEGRSD-----------------GDSIKKIINQMKPR-----------------------------
B9LMH6_HALLT/568-632TLTLQMG.TEVVDGFSGHAD-----------------RQGLENFVKTMNPR-----------------------------
E4XDJ0_OIKDI/544-606QVSIRCS.IEFIN.FEGRVD-----------------GESQLQLLSTIKPK-----------------------------
A4XI93_CALS8/376-437EYEVKCK.VEKYG.LSAHAD-----------------RDSILGFLAMLKPK-----------------------------
Q5NZR0_AROAE/398-462RHPIRAQ.IHQVGGYSAHAG-----------------QADLLRFVAGIPEM-----------------------------
Q4AAN8_MYCHJ/351-416SAIIKENGPDGYLHTSGHAY-----------------KAEHEKIFQLTKPK-----------------------------
A6VTF2_MARMS/412-470RYTIKAK.VQQISGYSAHAG-----------------QRDLLNFIKRMRVK-----------------------------
Q2GQR7_CHAGB/706-778TVSVQLR.IAFVD.FSGLHD-----------------KRSLNMLIPLIQPR-----------------------------
A0Q181_CLONN/391-454PIAVNAK.IYNLEGLSGHAD-----------------RNGLVDWIDKLMVR-----------------------------
A4RR19_OSTLU/496-558EINIRAT.IITVD.FEGKAD-----------------GKSVRTLITQAAPR-----------------------------
Q8TGX4_METAC/346-408VLALKPK.IEQYD.FSAHSG-----------------DSELKKLVKDFCKK-----------------------------
A3CWJ1_METMJ/370-436RAKMAGVRIFDELHVSGHAY-----------------REDHYEFLHLLNPQ-----------------------------
A8MJC1_ALKOO/395-459NIAVLAE.IHSIEGFSGHID-----------------QPGILDWLQGFKKK-----------------------------
Q73MR4_TREDE/396-461WHQVRAE.ILQINAFSAHAD-----------------YFESREWLDSLKNP-----------------------------
A7H6H0_ANADF/349-411GAQVAYEGLRPLH.VSGHAQ-----------------EAEQRRLIALARPE-----------------------------
A2SRA0_METLZ/371-437LLMRQGARIFDGLHVTGHAY-----------------YQEHYDLLSMLNPE-----------------------------
A5N1D0_CLOK5/382-443VIPVNCK.VKNVG.LSAHSD-----------------KSEIKSLINFLSPR-----------------------------
Q63J01_BURPS/379-443YVRVRAQ.VQMISSLSAHAD-----------------YGEILGWLGAQSSA-----------------------------
Q8TW11_METKA/577-643TLRIELR.VETVSGFSGHGD-----------------KIELTKYVRSIRPS-----------------------------
M3ZV83_XIPMA/104-171KLPLKMS.VDYIS.FSAHTD-----------------YQQTSEFIRALKPP-----------------------------
Q74MJ3_NANEQ/563-625LIKINLE.VRSFEGFSGHAD-----------------KGEIESFLRRVRPG-----------------------------
Q9HMJ7_HALSA/344-402VLPVSAQ.VEQYD.FSAHAD-----------------HAGLRAFLDDYRDA-----------------------------
A8MC21_CALMQ/354-414EIRVNAK.VYWFD.FSAHSG-----------------LEELINFISYFKDE-----------------------------
Q6LXH0_METMP/350-412AIPVNGK.VVKIE.FSAHAD-----------------YNSLLRFMKKI.PQ-----------------------------
Q04EG7_OENOB/358-421GANVVS..IKDNLRSSGHAS-----------------QNDLQFMLNFIKPD-----------------------------
Q7QC68_ANOGA/528-589PIEVNAQ.VQFID.FEGRSD-----------------GESLLKILSQLRPR-----------------------------
Q8SUC3_ENCCU/371-432SREIRLE.VKNLA.FSAHAD-----------------APGILNVVEQCSPR-----------------------------
Q3SMJ7_THIDA/401-465DIKVRAD.IYTLGGLSAHAD-----------------RSALLGWLGHFTNK-----------------------------
A8AA34_IGNH4/356-418GPRVEAR.TQWFD.FSSHAG-----------------ASELLEIIKSVNKL-----------------------------
A2D958_TRIVA/391-452DIIIKCK.VERIS.FSAHAD-----------------QFEIISLCDRVRPS-----------------------------
A4YH53_METS5/351-413SPLLKAR.LQMFD.FSSHAG-----------------KNQLLDIVKTSEAL-----------------------------
Q24X11_DESHY/400-464KVAVRAN.IRRMEGLSAHAD-----------------QPQLLEWLSCLGED-----------------------------
Q5QU60_IDILO/379-444WLPVKAR.IRSLEGLSGHAD-----------------YQEIADWLEQSSLK-----------------------------
Q88M01_PSEPK/407-469MYEIRAK.VVTVGGFSGHAD-----------------QAGLVGFVNAMSRV-----------------------------
Q6YPU2_ONYPE/359-424NVNVITHGPLINTHVSGHGN-----------------QNDLKLMLSLTKPK-----------------------------
Q11PK2_CYTH3/378-443SIPVAAK.IIYTDIFSGHTD-----------------VNGLIKYLGHQDKA-----------------------------
J9ZAT5_LEPFM/394-457MKDVRLA.LHSINGFSAHAD-----------------QADLLKWCGSMKIP-----------------------------
A2SLK7_METPP/396-460YVAVKAT.VSHLEGFSGHAD-----------------ADGLMEWLRGFETP-----------------------------
Q1J225_DEIGD/389-451EVIVRAQ.VHTIGGFSAHAD-----------------QDDLLTFLADTGNP-----------------------------
A2FCF8_TRIVA/383-447IIPRKIS.IDYVS.FSGHAD-----------------FNQTSRFITELKPK-----------------------------
INT11_DANRE/377-438TLDVKLQ.VEYMS.FSAHAD-----------------AKGIMQLIRMAEPR-----------------------------
A8A8E1_IGNH4/573-639QLEVRSH.VFSVEGFSGHSS-----------------RSELINWVKSVTPR-----------------------------
Q21X11_RHOFT/382-446DVELQAE.VVQLQSASAHAD-----------------ASQLLAWLRTMPQA-----------------------------
A3HWA3_9BACT/390-454EVPVKAK.IYQIDGLSAHAD-----------------QEELMDWAEGFTDR-----------------------------
B4SF65_PELPB/391-454RYPVRAT.VHTIGGLSAHGD-----------------QNDLLRWMGGFTNK-----------------------------
CPSF2_CAEEL/562-625RVEVSCR.IEFIE.YEGISD-----------------GESTKKLLAGLLPR-----------------------------
A0CN06_PARTE/363-424DYDIKMQ.INNMS.FSAHAD-----------------SRGIIQLVNHLQPK-----------------------------
A4X4Q7_SALTO/362-426GAVVVHKDVAKVH.VSGHAP-----------------AGELLYLLNIVRPS-----------------------------
A4CGY6_ROBBH/385-449TVSFKMQ.VAEIEGLSAHAD-----------------HAELLDWLSDIKIQ-----------------------------
Q1IJR0_KORVE/404-468IVPVRAQ.VATLEQFSDHAD-----------------TSELLEWLHTFKKA-----------------------------
Q2G602_NOVAD/350-412GVRIVTD.RQSMIHVSGHPG-----------------RPELMALYEWLRPE-----------------------------
RNJ2_STAA8/355-418GAHIIPN.NKKIH.ASSHGC-----------------MEELKMMINIMKPE-----------------------------
Q6LZD5_METMP/562-626AVKVNLS.VHTLEGFSGHSD-----------------RKQLIKYLRKLKPI-----------------------------
Q5FUV1_GLUOX/355-416GVTVLTD.KDAKVHTSGHAT-----------------SEDIRTLYRIVRPK-----------------------------
A5IZC2_MYCAP/354-418SPKVME..LNNFEFFHHHPA-----------------REDLAKLINILKPE-----------------------------
Q8ZYD9_PYRAE/561-625KINMRME.VVSIPGFSGHSD-----------------RRELMKYVEHMEPK-----------------------------

PF07522

Q296G1_DROPS/557-655.....PS..........................................YGRRISIIGIEYSEHSSYKELERFV------
Q9VND2_DROME/481-579....KPS..........................................YGKRISTIGIEYSEHSSYKELERFV------
Q16PI6_AEDAE/575-673....RPQ..........................................YRGRINIVGVEYSEHSSFNELKRFV------
Q8RZQ7_ORYSJ/227-334.......QKPS..................................LTEAVLDGCGVWHICFSIHSSRDELEQAL------
Q7QDQ3_ANOGA/486-584....KPQ..........................................YRGRINIVGIEYSEHSSFDELKRFV------
A2EC29_TRIVA/231-334TFDIYNE............................................IKVTSYDVPYSDHSSPMELTEFV------
DCR1C_CHICK/239-345IVRTGES................................................TYRACFSFHSSYSEIMDFL------
PSO2_SCHPO/403-529RAQLSSSLDSIISRPPK.....................FVEYDLRAIRGSTDKVAAFVAPYSEHSSFYDLTMFC------
DCR1A_CHICK/844-950MD.IKPQ..........................................TRGNITIYGIPYSEHSSYLEMKRFV------
A0A0D1CBW9_USTMA/699-829MDTVSPSLDRLIQWNQSR...................SFTFHNLLPTRDSTPDYMIYGVPYSEHSSFFELTAFA------
Q6ZD68_ORYSJ/209-321TK.....RKPA..................................LTEPMRDEFGVWHVCFSMHSSREELEQAL------
Q4Q2L8_LEIMA/388-491SE..................................................KYTLLRVPYSEHCAFHELLEFV------
SNM1_ARATH/360-467LDLIKPT..........................................SRGKITIYGVPYSEHSSFTELREFV------
DCR1A_MOUSE/900-1006AD.IIPQ..........................................TRGNISIYGIPYSEHSSYLEMKRFV------
A6RF66_AJECN/673-802TD..SPTVSSVLYSDSWKP..................RFATKDLIPQRGSNQISSCYSVPYSEHSSFRELTMFC------
Q8IK95_PLAF7/674-779.......F........................................YERNNISIFLIPYSEHSNLDELKNFV------
Q8LQQ4_ORYSJ/223-351KSGVKSPAKSIRCKGLDEG..................AIEMDYDPLSPPKLFEKDSYSLPYSEHACFAELENFM------
A2GFK2_TRIVA/225-328QITYQGP............................................IKVTLYEVPYSDHSSPQELLNFV------
A7E8T1_SCLS1/835-964VD..SPPIHTILNASNWRS..................EYDMGELIPQRGSTKEAQCFGVPYSEHSSFRELTMFV------
DCR1C_DANRE/239-345VVKMGSS................................................SYRACFSFHSSYLEVKDFL------
A4S4B7_OSTLU/228-334RATSRRQ...........................................RGRLIQYGLPYSEHSSLNELREFV------
Q4YJX0_PLABA/192-297.......F........................................YEKNNMSVFLIPYSEHSNLDELKDFV------
A7RZG8_NEMVE/216-320LSATRPV..........................................TKGPISIYGVPYSEHSSYEEMKRFV------
DCR1C_HUMAN/239-345IVRTGES................................................SYRACFSFHSSYSEIKDFL------
DCR1_DICDI/481-582LN................................................RGPTTFYSVAYSEHSSFNELRDCI------
Q6C9D1_YARLI/448-581QANEQATDLRPSYYDFGDLE................YNVENLDRNLERSAIEPVQKYNVPYSEHSSFVELRAFC------
Q6CJP1_KLULA/366-495YTLWDEFERKNWVKDTLSGE................TPFAIDYFTKQKRSQGKIYHFNVPYSEHSSFKDLCLFS------
Q6FR52_CANGA/556-712FQYDGELSYDDNFKLRVKYCMDLLKQDEARPTQNFADVSSLEWLRMQYKPRERYQIFRVPYSEHSSFRELLKFC------
C8VBT0_EMENI/673-800LE..NPPVSTVLYSSHWKT..................PFSVRDLTPQRGSTRESACFGVPYSEHSSFRELTMFC------
F4IDZ7_ARATH/235-347SGSIQKQRKVR..................................FSEAVKDEFGLWHVCYSMHSSRAELESAM------
Q5KDG6_CRYNJ/644-773MLP...DVNTIIRRDQAR...................RFGEGDLKTMRGSSRNFMMYGVPYSEHSSFFELTCFA------
Q7XV88_ORYSJ/357-463LDLIKPS..........................................SRGKITIYGVPYSEHSSFSELREFV------

PF07521

Q7UMQ3_RHOBA/427-488---------------------------------------------------PKE.IRLV.HGDYAAKRALTQKL......
Q8IL83_PLAF7/431-493---------------------------------------------------N...VVLV.HGDKNELNRLKNKL......
E7LXW1_YEASV/359-428---------------------------------------------------N...IILV.HGEANPMGRLKSALLSNFAS
A3DMW0_STAMF/352-417---------------------------------------------------LKN.IIIV.HGEPDSASNLASMA......
Q4JB02_SULAC/555-622---------------------------------------------------PKN.LVLN.HGEPSAISSFKRLV......
Q6AQL6_DESPS/455-518---------------------------------------------------VKS.IALV.HGEVEQSLAFAEHL......
A8ZYV1_DESOH/454-517---------------------------------------------------IRR.AVVV.HGEKEQSACFAKSL......
A6Q9T8_SULNB/395-458---------------------------------------------------QR..IFLI.HGEEEKQEVLRKVM......
A1RXC5_THEPD/357-418---------------------------------------------------SK..VVLV.HGEEEAAVKLAELS......
A1U408_MARHV/381-445---------------------------------------------------PEK.VYVT.HGEAVASDTMRKRI......
Q3AAG6_CARHZ/390-454---------------------------------------------------PAQ.IYLV.HGEDEARLNLKKLI......
A8BNK1_GIAIC/412-487---------------------------------------------------N...VAFI.HGSEKSISSLKRTIANETRV
Q0W8H2_METAR/362-424---------------------------------------------------GTTDVFCV.HGDR..TEEFAAWI......
Q0W2D5_METAR/563-627---------------------------------------------------PER.IITN.HGDENKCLDLASSI......
Q72BD6_DESVH/353-407---------------------------------------------------L...LVPI.HTEKK..QDYAKHF......
Q8ZTD5_PYRAE/354-416---------------------------------------------------TK..IILV.HTDPLTAAPFIRRL......
A8ZWQ7_DESOH/346-410---------------------------------------------------Y...FIPV.HGERRHLIHHARLA......
Q92Z81_RHIME/392-456---------------------------------------------------SAG.VFLV.HGEDEALEGIRERL......
Q6MLH4_BDEBA/380-444---------------------------------------------------PKR.MFLV.HGEPVAADELRKRI......
Q74HX7_LACJO/274-324---------------------------------------------------I...LAPVHTLHPELEE............
A0JWK6_ARTS2/385-449---------------------------------------------------PRM.TYIT.HGEPEASDALRIRI......
A1SFD7_NOCSJ/387-451---------------------------------------------------PEI.VYVV.HGEPAASAALARRI......
A8AB05_IGNH4/310-359---------------------------------------------------E...VYLV.HGDE.ECRSEAERM......
A6TST8_ALKMQ/372-422---------------------------------------------------K...IIPI.HTERSDL..FAEAF......
A4CMY8_ROBBH/383-447---------------------------------------------------PGH.IFLV.HGEPTAADALRVKL......
CPSF2_DICDI/550-612---------------------------------------------------K...LVLI.RGSEQQSQSIENYV......
O29718_ARCFU/337-399---------------------------------------------------GAEVVFTI.HGEE..TEAFAEWI......
Q6L0H4_PICTO/339-395---------------------------------------------------T...VVLC.HGDQREKLKEALPE......
Q15V20_PSEA6/396-459---------------------------------------------------PK..VVLV.HGEPKAQEALAQKL......
R7D7I2_9FIRM/392-456---------------------------------------------------PEK.VFVT.HGDDEVTEIFARRL......
B3E8Q6_GEOLS/353-409---------------------------------------------------Q...LVPV.HTEFPADYEF..YF......
Q2S180_SALRD/394-456---------------------------------------------------T...VLLI.HGDPDAKDWMAEHI......
Q18IP5_HALWD/406-470---------------------------------------------------G...ISLI.HGPPNAAAHLQEYL......
Q81SC3_BACAN/350-410---------------------------------------------------H...TVLV.HALKEDTDRLQKKL......
A4S2Z0_OSTLU/352-408---------------------------------------------------H...FLPV.HGEYAFLRAHEQLA......
Q6L180_PICTO/565-629---------------------------------------------------PQR.ILVN.HGDGDKCYEFSRLI......
Q9CF63_LACLA/350-413---------------------------------------------------N...LIPI.QGEYRELSAHADLA......
A2BK26_HYPBU/355-417---------------------------------------------------Y...IVVV.HSEADVAVKYAELL......
Q8U1V4_PYRFU/365-431---------------------------------------------------N...IVPA.HGEFRMLTHYAELA......
A0RY50_CENSY/347-409---------------------------------------------------PE..VLTV.HGDRESCSKFAEEI......
A9A2U6_NITMS/573-637---------------------------------------------------LRR.VLVN.HGERKKSENLAMNI......
Q0ABE3_ALKEH/392-455---------------------------------------------------PP..IALV.HGESGAMDTLADEL......
CPSF2_HUMAN/528-591---------------------------------------------------Q...LIIV.HGPPEASQDLAECC......
B9LMH6_HALLT/568-632---------------------------------------------------PEK.VLCV.HGDESSVQDLSSAL......
E4XDJ0_OIKDI/544-606---------------------------------------------------E...LILI.RTKEKYKEKLFKDI......
A4XI93_CALS8/376-437---------------------------------------------------T...VVFA.HGSEEAISQLSDMA......
Q5NZR0_AROAE/398-462---------------------------------------------------PAE.IRIV.HGDDEAKAALKKKL......
Q4AAN8_MYCHJ/351-416---------------------------------------------------Y...FFPY.HGEYRMCLAHSRTA......
A6VTF2_MARMS/412-470---------------------------------------------------PQK.IHLV.HGDNNAKRTLKGLI......
Q2GQR7_CHAGB/706-778---------------------------------------------------K...LILV.AGAEEETLALAADC......
A0Q181_CLONN/391-454---------------------------------------------------PKE.ILLV.HGDTKSQQSFKELL......
A4RR19_OSTLU/496-558---------------------------------------------------R...VVLV.HGDAKETKTLKDAL......
Q8TGX4_METAC/346-408---------------------------------------------------GTERVFVM.HGDK..TEAFAQWI......
A3CWJ1_METMJ/370-436---------------------------------------------------H...VIPS.HGDIGMTGGYAKFA......
A8MJC1_ALKOO/395-459---------------------------------------------------PKK.IFLV.HGEEDSLSTLSELI......
Q73MR4_TREDE/396-461---------------------------------------------------KLKTIFLV.HGEPKAQTYFTQYL......
A7H6H0_ANADF/349-411---------------------------------------------------H...FVPI.HGEYRHLARHAAHA......
A2SRA0_METLZ/371-437---------------------------------------------------H...IIPS.HGPFAMKGGYVALG......
A5N1D0_CLOK5/382-443---------------------------------------------------N...IFIV.HGNEDVIENFCMQL......
Q63J01_BURPS/379-443---------------------------------------------------PAR.TFVT.HGEPAAADALRRRI......
Q8TW11_METKA/577-643---------------------------------------------------PPSKVFTN.HGEPRACKYFSNHL......
M3ZV83_XIPMA/104-171---------------------------------------------------H...VILV.HGEQNEMARLKAAL......
Q74MJ3_NANEQ/563-625---------------------------------------------------R...VVIN.HGERSKVLHLASYL......
Q9HMJ7_HALSA/344-402---------------------------------------------------T...VLVN.HGDD..CAAFADAL......
A8MC21_CALMQ/354-414---------------------------------------------------TN..ILIV.HSSPRNALRLSEHL......
Q6LXH0_METMP/350-412---------------------------------------------------PDK.AIVM.HGERYQALSLAMTI......
Q04EG7_OENOB/358-421---------------------------------------------------Y...FFPV.SGEYRVFSVADFLA......
Q7QC68_ANOGA/528-589---------------------------------------------------R...VVVV.RGSPANTSHIAEHC......
Q8SUC3_ENCCU/371-432---------------------------------------------------N...VMLV.HGEKSRMKVLKRSI......
Q3SMJ7_THIDA/401-465---------------------------------------------------PRR.VFVV.HGEEDVATGFAATI......
A8AA34_IGNH4/356-418---------------------------------------------------KK..VIIV.HSEESTALHFAQRV......
A2D958_TRIVA/391-452---------------------------------------------------K...VVTI.HGDKPSVDALATRI......
A4YH53_METS5/351-413---------------------------------------------------EK..IVVV.HASPDSAQAFSDYV......
Q24X11_DESHY/400-464---------------------------------------------------AEN.IILV.HGEPDVQKTFAQKI......
Q5QU60_IDILO/379-444---------------------------------------------------PNTPIQLV.HGELDALETFRDYL......
Q88M01_PSEPK/407-469---------------------------------------------------PGR.VVLV.HGEQRAKLILQQVL......
Q6YPU2_ONYPE/359-424---------------------------------------------------Y...FIPV.HGEHRMLIAHKNLA......
Q11PK2_CYTH3/378-443---------------------------------------------------KLKKIFLV.HGEHQSMLDFEKRL......
J9ZAT5_LEPFM/394-457---------------------------------------------------DR..VFLV.HGEHRSLSAYREKL......
A2SLK7_METPP/396-460---------------------------------------------------PER.CFVV.HGEPVAADTLRLRI......
Q1J225_DEIGD/389-451---------------------------------------------------R...VWLI.HGEVPVMEEFLPVL......
A2FCF8_TRIVA/383-447---------------------------------------------------R...IVLI.HGVCGLMMQLKEKL......
INT11_DANRE/377-438---------------------------------------------------N...MLLV.HGEAKKMEFLKDKI......
A8A8E1_IGNH4/573-639---------------------------------------------------PKN.IILN.HGEPSRIEGLARVL......
Q21X11_RHOFT/382-446---------------------------------------------------PDQ.VYVT.HGEWGASDEFRKRI......
A3HWA3_9BACT/390-454---------------------------------------------------PKI.TFII.HGEEQSATVLGQKL......
B4SF65_PELPB/391-454---------------------------------------------------PE..VFVV.HGDQPAKSIFRNAL......
CPSF2_CAEEL/562-625---------------------------------------------------Q...IIVV.HGSRDDTRDLVAYF......
A0CN06_PARTE/363-424---------------------------------------------------S...IAFV.HGEYHRMKTLGAEI......
A4X4Q7_SALTO/362-426---------------------------------------------------N...LMPV.HGEWRHLRAHARLG......
A4CGY6_ROBBH/385-449---------------------------------------------------PEK.IFIV.HGEREGAEALKQGI......
Q1IJR0_KORVE/404-468---------------------------------------------------PSQ.TWLV.HGEPDAAQKLRDAM......
Q2G602_NOVAD/350-412---------------------------------------------------I...LVPV.HGEIRHMAEQAQLG......
RNJ2_STAA8/355-418---------------------------------------------------Y...FIPV.QGEFKMQIAHAKLA......
Q6LZD5_METMP/562-626---------------------------------------------------PDR.ILTV.HGEVSKCIDLASTA......
Q5FUV1_GLUOX/355-416---------------------------------------------------Y...SIPT.HGEWRHLTAHAALA......
A5IZC2_MYCAP/354-418---------------------------------------------------Y...VIPV.QGLYRYLQDAQRYI......
Q8ZYD9_PYRAE/561-625---------------------------------------------------PKK.IVLI.HGEPSKIISLATSI......

PF07522

Q296G1_DROPS/557-655--------------------RFI-KPR..RIISTVPVGR
Q9VND2_DROME/481-579--------------------RFL-KPK..RVISTVPVGR
Q16PI6_AEDAE/575-673--------------------RYL-RPQ..EVISTVPYGN
Q8RZQ7_ORYSJ/227-334--------------------ELL-QPQ..WVISTTPPCF
Q7QDQ3_ANOGA/486-584--------------------QFL-RPH..EVISTVPYGN
A2EC29_TRIVA/231-334--------------------KAV-KPA..KVIPTTTKNK
DCR1C_CHICK/239-345--------------------SYI-RPV..NVYPNVLPVG
PSO2_SCHPO/403-529--------------------LSM-NIG..HIIPTVNVGS
DCR1A_CHICK/844-950--------------------QWL-KPQ..KIIPTVNVGD
A0A0D1CBW9_USTMA/699-829--------------------LST-RYD..RIIATVNVGS
Q6ZD68_ORYSJ/209-321--------------------RFI-QPK..WVISTTPPCM
Q4Q2L8_LEIMA/388-491--------------------AFV-NPA..RVVPTVSEEG
SNM1_ARATH/360-467--------------------QFL-RPD..KIIPTVNNGN
DCR1A_MOUSE/900-1006--------------------QWL-KPQ..KIIPTVNVGS
A6RF66_AJECN/673-802--------------------CAL-RIT..KVIPTVNVGS
Q8IK95_PLAF7/674-779--------------------KSI-KPC..NILPTVFYNE
Q8LQQ4_ORYSJ/223-351--------------------LIV-RPS..TVIGIVSTSF
A2GFK2_TRIVA/225-328--------------------KVV-KPK..KLVSTTSRSQ
A7E8T1_SCLS1/835-964--------------------MGL-RIE..KVVPTVNVGT
DCR1C_DANRE/239-345--------------------SYI-CPV..NIYPNVIPLG
A4S4B7_OSTLU/228-334--------------------RFM-NPK..FIFPHVNNDG
Q4YJX0_PLABA/192-297--------------------KSI-KPC..SICPTVFSNI
A7RZG8_NEMVE/216-320--------------------QFT-RPT..KIVPTVNVHS
DCR1C_HUMAN/239-345--------------------SYL-CPV..NAYPNVIPVG
DCR1_DICDI/481-582--------------------DHF-RPT..QIIPTVDCDS
Q6C9D1_YARLI/448-581--------------------LNM-AAT..TIIPTVNMSA
Q6CJP1_KLULA/366-495--------------------TKL-KWD..KIIPTVNLSQ
Q6FR52_CANGA/556-712--------------------ISV-PSK..NIISTVNVDN
C8VBT0_EMENI/673-800--------------------CAL-RIG..RIIPTVNVG.
F4IDZ7_ARATH/235-347--------------------QLL-SPK..WVVSTVPSC.
Q5KDG6_CRYNJ/644-773--------------------LSL-PGADLKMIATVNVGN
Q7XV88_ORYSJ/357-463--------------------MFL-RPQ..KVIPTVNVGN

PF07521

Q7UMQ3_RHOBA/427-488....................TEK.G..--...YHLI...
Q8IL83_PLAF7/431-493........I...........EEKQY..--...LSVFT.P
E7LXW1_YEASV/359-428LK......X...........TDN.E..--...VHVFN.P
A3DMW0_STAMF/352-417........V...........EFL.GND--...ININV.P
Q4JB02_SULAC/555-622........ES.........GKIK.G..--...IDNVYAP
Q6AQL6_DESPS/455-518....................RGE.G..--...FDVSI.P
A8ZYV1_DESOH/454-517....................KAE.G..--...IDAVV.P
A6Q9T8_SULNB/395-458........G...........EKL.H..--...EKAHI.V
A1RXC5_THEPD/357-418....................VKA.G..--...HETFV.P
A1U408_MARHV/381-445........T...........EKF.G..--...WNAEV.P
Q3AAG6_CARHZ/390-454........E...........EKY.R..--...IPCYL.P
A8BNK1_GIAIC/412-487NFSEGGKEA...........DKE.E..--...ISFHY.P
Q0W8H2_METAR/362-424........R...........QEY.D..--...VNAYA.P
Q0W2D5_METAR/563-627........Y...........KKY.K..--...LETKS.P
Q72BD6_DESVH/353-407....................QP.....--...IQVKA.V
Q8ZTD5_PYRAE/354-416........A...........KEG.Y..--...DNIYL.P
A8ZWQ7_DESOH/346-410....................KQA.GIP--E..ENIIL.P
Q92Z81_RHIME/392-456........S...........TFL.P..--...QDHLI.R
Q6MLH4_BDEBA/380-444....................DKELK..--...WYVTV.P
Q74HX7_LACJO/274-324....................NPF.G..--...ERIL..P
A0JWK6_ARTS2/385-449........K...........REL.G..--...WRVRV.P
A1SFD7_NOCSJ/387-451........T...........EDL.G..--...WPAVV.P
A8AB05_IGNH4/310-359........................G..--...FHN...L
A6TST8_ALKMQ/372-422...........................--...EKVYL.A
A4CMY8_ROBBH/383-447........F...........AER.G..--...WVARI.P
CPSF2_DICDI/550-612........KE.........NIRT.K..--....GIYI.P
O29718_ARCFU/337-399........K...........DNI.G..--...VEAYA.P
Q6L0H4_PICTO/339-395...........................--...YNFIL.P
Q15V20_PSEA6/396-459........W...........EDK.N..--...IRAVI.P
R7D7I2_9FIRM/392-456........Q...........EEL.G..--...LDSMA.P
B3E8Q6_GEOLS/353-409...........................--...GNCLM.V
Q2S180_SALRD/394-456........K...........EAHPE..--...TEVHR.P
Q18IP5_HALWD/406-470........S...........DNT.TA.--...STIQV.A
Q81SC3_BACAN/350-410....................STA.G..--...YENVY.S
A4S2Z0_OSTLU/352-408....................RQS.G..--.........V
Q6L180_PICTO/565-629........R...........SKF.G..--...IDAIS.L
Q9CF63_LACLA/350-413....................MEM.DIL--P..EHIFI.A
A2BK26_HYPBU/355-417....................RST.GIP--...EEVIV.A
Q8U1V4_PYRFU/365-431....................EEE.GYM--IG.KDVFI.S
A0RY50_CENSY/347-409........T...........EAT.G..--...FKAHA.A
A9A2U6_NITMS/573-637........R...........RMH.R..--...VPAHY.P
Q0ABE3_ALKEH/392-455........H...........RRY.N..--...VSVRT.P
CPSF2_HUMAN/528-591........RA.........FGGK.D..--...IKVYM.P
B9LMH6_HALLT/568-632........Y...........HDY.N..--...MRTFA.P
E4XDJ0_OIKDI/544-606........K..........SRVQ.G..--...IRIHM.P
A4XI93_CALS8/376-437........I...........KEI.E..--...SAVLI.P
Q5NZR0_AROAE/398-462....................EEA.G..--...ATCVLVP
Q4AAN8_MYCHJ/351-416....................IES.GVD--P..KNVII.P
A6VTF2_MARMS/412-470....................EME.N..--.........P
Q2GQR7_CHAGB/706-778........KKLLSAQLASGSSQS.A..--...IDVFT.P
A0Q181_CLONN/391-454....................DSK.G..--...FKSRI.M
A4RR19_OSTLU/496-558........T...........AGLPG..--...VQIDA.P
Q8TGX4_METAC/346-408........S...........EEI.G..--...VEAYA.P
A3CWJ1_METMJ/370-436....................EEM.GYT--LG.NDLHI.L
A8MJC1_ALKOO/395-459........N...........ERY.N..--...IPTVI.P
Q73MR4_TREDE/396-461........N...........ENG.Y..--...NDVKT.V
A7H6H0_ANADF/349-411....................AAE.G..--...VRGRHLL
A2SRA0_METLZ/371-437....................SEF.GYT--LN.KEVHI.M
A5N1D0_CLOK5/382-443........S...........SEV.K..--...GKVYA.P
Q63J01_BURPS/379-443........E...........ETL.H..--...WRCDV.P
Q8TW11_METKA/577-643........RR..........TVR.K..--...VFSMA.P
M3ZV83_XIPMA/104-171........I...........REYEDND--QVHIEVHN.P
Q74MJ3_NANEQ/563-625........R...........KKL.N..--...VETNA.P
Q9HMJ7_HALSA/344-402....................RDA.G..--...FTARA.P
A8MC21_CALMQ/354-414....................DER....--....NIHVTL
Q6LXH0_METMP/350-412........W...........KTL.K..--...IPALA.P
Q04EG7_OENOB/358-421....................QEV.GIK--K..NHIFL.S
Q7QC68_ANOGA/528-589....................QQNIG..--...ARVFT.P
Q8SUC3_ENCCU/371-432........E...........ERF.G..--...IPTFL.P
Q3SMJ7_THIDA/401-465........A...........TQF.G..--...WDAIA.P
A8AA34_IGNH4/356-418........R...........EET.G..--...LDVIV.P
A2D958_TRIVA/391-452........T...........QTT.G..--...IPAEA.P
A4YH53_METS5/351-413........K...........EKL.G..--...VEVLV.P
Q24X11_DESHY/400-464........Q...........EKF.G..--...KIPWI.P
Q5QU60_IDILO/379-444........M...........QNT.T..--...YNVDV.A
Q88M01_PSEPK/407-469....................RAR....--...RETHN.P
Q6YPU2_ONYPE/359-424....................LEC.GIP--E..SNIFI.L
Q11PK2_CYTH3/378-443........H...........EEG.Y..--...NNIEI.P
J9ZAT5_LEPFM/394-457....................SEA.G..--...WKHAHVP
A2SLK7_METPP/396-460....................QDELG..--...WRVSV.P
Q1J225_DEIGD/389-451....................AQR.G..--...LTANIMP
A2FCF8_TRIVA/383-447................LQMFVED.G..--...LEVYT.P
INT11_DANRE/377-438........E...........QEF.S..--...ISCFM.P
A8A8E1_IGNH4/573-639........SR.........TVAR.G..--...MKIYT.P
Q21X11_RHOFT/382-446....................KHELG..--...WRAIM.P
A3HWA3_9BACT/390-454........H...........DEL.G..--...WQTVI.P
B4SF65_PELPB/391-454........E...........ERL.G..--...LKASI.P
CPSF2_CAEEL/562-625....................ADS.GFD--...TTMLKAP
A0CN06_PARTE/363-424........I...........DKI.Q..--...IRVDC.P
A4X4Q7_SALTO/362-426....................VES.GVA--A..DRVVL.C
A4CGY6_ROBBH/385-449........K...........EIY.D..--...WDSEV.P
Q1IJR0_KORVE/404-468........I...........KAL.H..--...WNVNV.A
Q2G602_NOVAD/350-412....................LDE.G..--...IPKAIVQ
RNJ2_STAA8/355-418....................AEA.GVA--P..EKIFL.V
Q6LZD5_METMP/562-626........Y...........KLF.K..--...KETKA.P
Q5FUV1_GLUOX/355-416....................HEM.G..--...AEPIL.L
A5IZC2_MYCAP/354-418....................VKNVGFN--S..KNVLV.L
Q8ZYD9_PYRAE/561-625........E...........LKY.K..--...ITTII.P

This alignment is coloured according to the ClustalX colouring scheme:

 
Glycine (G)
 
Proline (P)
 
Small or hydrophobic (C,A,V,L,I,M,F,W)
 
Hydroxyl or amine amino acids (S,T,N,Q)
 
Charged amino-acids (D,E,R,K)
 
Histidine or tyrosine (H,Y)

For UniProt-based alignments, we also add some additional mark-up to the alignments where appropriate. Active site information is shown as follows:

 
Active site (residue annotated in SwissProt as an active site)
 
Predicted active site (residue aligns in a Pfam alignment with a SwissProt active site)
 
Predicted active site (residue annotated in SwissProt as a potential active site)

Some UniProt sequences can be mapped to protein structures, in which case we also show the secondary structure definition. These lines are shown below the sequence to which they apply and are marked (SS). The meaning of each of the symbols is as follows:

C
Random coil
H
Alpha-helix
G
3(10) helix
I
Pi-helix
E
Hydrogen bonded beta-strand (extended strand)
B
Residue in isolated beta-bridge
T
H-bonded turn (3-turn, 4-turn, or 5-turn)
S
Bend (five-residue bend centered at residue i)
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