Sequence alignment for CL0399

PF01177

A4CJF0_ROBBH/7-221IGGT..SWHSTIEYYRCINEQVGEEIGRH.ANPP-----LIL-HSIN.......IE......LM.......REQ..DPRK
A2SC58_METPP/7-225LGGM..SWESTLIYYRDLNRGVAQRLGGL.HSAS-----LRL-HNLD.......FE..PVAALQ.......REG..RWGA
A8AI88_CITK8/10-228LGGM..GPLATLDLMHKLLRATPASSDQQ.QIPH-----VVW-NVPQ.......IA..DRQQAL.......AGT...GPS
Q04F20_OENOB/8-227LGGM..GTMATENFVRTLDRLTEAHSDQN.FLNY-----LVF-NHAC.......IP..DRTAYI.......FDR..TKDN
Q6FF80_ACIAD/8-224LGGM..GPQATVDAMNKIIKNTSAHSDQE.HIPV-----IIV-SIPD.......IP..DRTKSI.......INH...DDK
Q250X9_DESHY/29-245IGML..TPSSNTALEPVCSRMVSGLEN......L-----VAM-HYSRL...EVTKI...SLEKD.......ALSQFDLD.
Q2INC6_ANADE/8-223VGGL..GPEGTVHYYRKLTALLAGLPLDL.GRPG-----IVV-DHVW.......ID..RFSGLL.......RAG..ADPE
Q6L2R8_PICTO/8-216IGGM..GPVATVKFIEKLTSMTDAEIDQD.HVRY-----VLY-NDPE.......IP..DRIEAY.......FEN...MES
Q897B7_CLOTE/8-226IGGM..GPKATVDLYNKIVDYTDASSDQD.HLHV-----VID-GNAK.......IP..DRTSYI.......LGN...GKS
Q4P1R6_USTMA/36-261LYIL..NPNSSSVITAALASNLSAQTPA...GCT-----STF-VTGPP....TCPA...TIQDSA.....E...MIISTA
A8F5P0_THELT/7-216VGGM..GSLATVDFLKKVVEHTKAEKDQD.HIRM-----IVD-FNTS.......VP..DRTAAI.......LDD...GED
Q5LQ34_RUEPO/249-469VGGV..GPAATVDFLKKIVEGTAAERDQD.HIKL-----IVE-QNPQ.......IP..DRTENL.......VKG...GPD
A9BQL6_DELAS/14-243LGGM..GPAAGADFVRLFVQACTAHLQQQ.GLPV-----HDQ-AYPEHWLVQLPMP..DRSAAL.......RADPQSPTG
Q12P73_SHEDO/7-222LGGM..SWPSTIEYYRLLNEKAQAHLGEG.HSAR-----LLL-SSMD.......YF..DIRQHY........PN..GWDK
A9BGM9_PETMO/16-231LGGM..GPAATAEFVNILIRQFPAPCDQE.YPKI-----ILF-SNPQ.......IP..DRNKAI.......LEN...GQD
Q97UR3_SULSO/6-223VGVI..IPSSNTTVEYEFSNVFNQIKEY.....R-----ITP-HFSR............IKLRNV....TIEDLAEMER.
A1SP17_NOCSJ/7-224VGGM..SWESSAAYYEALNQGVEERVGGL.ASAR-----TAM-VSVD.......FA..EVTALQ.......EQE..RWDD
Q5JD97_THEKO/9-223LGGM..GPLATADLFRRIVERTPARRDQD.HPRI-----IIY-NNPK.......IP..DRTAFI.......LGN...GPD
B5EHN1_GEOBB/7-224IGGL..GPEATLDYYKRIIEASRGAGTLD..TPE-----III-YSVS.......LQ..EVLDLA.......ARR..EWSN
Q8Y2X0_RALSO/7-225IGGI..GPESTVAYYRKIIHGVQEKAGRE.NLPR-----LSI-ESLS.......AF..TVFNLC.......RAK..QFDQ
Q6FWC7_CANGA/6-225IGGI..GPEATTHYYISIIKQFQDAVGSDKVLPE-----MVV-ESIN.......MY..HMFEML.......EQR..QYDD
A1TM90_ACIAC/9-232IGVF.DSGVGGLSVLRALRAELPHER.......F-----VYL-ADSG......NAPYGERGDAY................
Q1GTC8_SPHAL/7-224IGGM..SWASTELYYRHLNKGVQKRLGTG.CSAP-----ILM-ESLN.......YC..DLSRIT.......TDE..QWAH
Q5JKS2_ORYSJ/89-319IGVMGISASSSLRFLQKL.VHWSTRDGEE.APPF-----LVC-NDPL............LKKELMS...SQNSQRPSDCN
Q8U0C4_PYRFU/10-224IGGM..TPESTCYYYRKYIEISRKKFRKY.EYPE-----LLI-YSIN.......FR..DFF..M.......NPE..GWEG
Q7P1U9_CHRVO/27-245IAGV..TVPGAVDCLSKIHRLCADRFPHH.HHPR-----FAL-DQPD.......FG..VVHQAQ.......DDD..RWDR
Q16BZ8_ROSDO/10-226LGGM..GVEATLELMKRVHAATPAEDDQD.HVPM-----FVD-MNPQ.......VP..SRIRHV.......IEK..TGPD
Q7W0P3_BORPE/17-237LGGM..GPMAGASFMQRLVALTEAACDQQ.HVPA-----ILW-NDPR.......VP..DRPAGQ.......SGQ...GAD
A5G0P7_ACICJ/7-220IGGL..ALRAGIFYYEQIQKRFAASQAP...LQ.-----LVL-SHAD.......VL..RVLSYV.......AAE..DRIA
Q7MS48_WOLSU/7-225LGGL..AYPSTAEYYLKINRQVHATLGKH.HSAP-----LWI-HSFD.......FE..PIAQAQ.......ASG..SWTI
A9WE52_CHLAA/2-208IGIF.DSGLGGLSVMRAIHERLPDTD.......L-----LYL-ADSA......YCPYGPRPLSE................
B0JPW0_MICAN/11-224LGGM..GPVVTAEFLKSIYEYNPFIDKEQESPNV-----IVF-SFPS.......AP..DRTGSI.......DSG.KERE.
B2UHS6_RALPJ/3-209ILVV..NPNISESVTELIHAEARRSVSP...GTT-----LTM-ATAP.....FGVA...YIETR......FEAL..VGG.
B4EC48_BURCJ/3-210IRLI..NPNTTQRMTDAMGRCAREVAAA...GTE-----IVA-VSPP.....MGPP...SIEGY......YDEA.LATP.
I3U2M8_ENTFC/8-225LGGM..GTMATESFVRLINHRTKATKDQE.YLNY-----VLF-NHAT.......VP..DRTAYI......LD.R..SEEN
I3WGY8_BIFBI/9-232LGGM..GTLATESYIRLVNRETHAHSDQE.FLDY-----VVF-NDAA.......VP..DRTAFI.......IGQ..SDDD
J9ZES5_LEPFM/12-224IALF.DSGVGGLTVLRHFWETFPDRD.......F-----AYL-GDMA......RFPYGTKSRET................
MURI_HELPY/3-218IGVF.DSGVGGFSVLKSLLKAQLFDE.......I-----IYY-GDSA......RVPYGTKDPTT................
Q4FL57_PELUB/5-243LGGM..GTQAGLDFCNKLAMLNRGKSDQE..YPL-----FML-YNKS......NIP..GRPESIGVQTKSLS......TI
Q5NNC8_ZYMMO/7-224IGGI..GPESTLLYYKKLVYGANNRIGSQ.FYPN-----LTV-ESLN.......VF..DILRLC.......EDK..DYT.
Q5ZT55_LEGPH/25-230IGVF.DSGMGGLTVLRALRDKLPHES.......F-----VYL-GDTA......RLPYGTKSPDT................
Q74HN5_LACJO/8-224IGGM..GTIATESYVRLINHRVKITKDQD.YLNY-----ILV-NDAQ.......IP..DRTAYI......MD.H..SQPN
MURI_LACJO/6-213IGVL.DSGLGGLTVLKKVIEKMPNES.......T-----IFI-GDQA......NMPYGDRSREE................
Q81LA8_BACAN/7-216IGVI.DSGVGGLTVAKELIRQLPKER.......I-----IYL-GDTA......RCPYGPRSREE................
Q81R35_BACAN/7-223IGGM..SWESTAEYYRIINEEIKSRLGGL.HSAK-----CLI-NSVD.......FE..EIERYQ.......SSG..DWD.
R5ZKA2_9ACTN/7-237IGGM..GAEATSYYYNQVVRHTAAACDQE.HIDM-----VVL-SKST.......MP..DRTLAI.......KTG..EHA.
R7EMK1_9BACE/12-229IGIF.DSGYGGLTILSKIREALPQYD.......Y-----IYL-GDNA......RAPYGTRSFEI................

PF07302

W5W931_9PSEU/4-222LGLVTIGQTPRVDLVAELRALL.PPCRILEHGAL.....DGL.AEHTI.AAMAPSPG.EPALTTRLADGRA...VVYRHD
D7GS63_9FIRM/4-220IGAITVGQSPRVDLIPEIQPILGDSVEIIQAGAL.....DGL.SKEEI.SKFVPRPG.ENVLVSRLTDGTS...ATFGES
A8I8Z9_AZOC5/6-223MGVVVIGQSPRPTIAAEIAAVVSPHFEIDLRGAL.....DGM.TRSEI.DAIPPKDG.ADSLFTLLPSGDA...VKISKK
A7MLX0_CROS8/5-224LAILTIGVVPVSEILPLLTEHI.DEQHITHISLM.....GKL.SRAEAMDDYGASGH.EETIITMLADGEK...ATVSKA
E3HTW6_ACHXA/8-227VAFFTIGQSPRSDVVPEMAPLLGEQVRIDEFGAL.....DGL.DAAGL.AALAPKPG.EYRFATRMRDGSQ...IELDAA
G2NY32_STRVO/21-248LGLVTIGQAPRADLRPDAEPLL.PGVRLVEHGALDAERFDGD.AEAATRRLLAPEVG.EAPLVSRLRDGRS...VLLGHG
B2VIS4_ERWT9/6-224.VTLTIGQSPRIDILPMLLTYL.PEAQIAHAGLL.....DGL.SRQQIEQEFGKQDG.DRTLVSRLNDGSQ...VLLASH
Q89Q90_BRADU/10-227IGVVVIGQSPRPTVASEIAAVLSPGIEIELRGAL.....DGM.SRAEI.DAIPPMDG.YDTLFTLLPNGDG...VTISKK
R5F3Q4_9CLOT/6-223IGLITIGQSPRTDVVPEIREILGQDVQILETGAL.....DGL.SMEEI.EGLNPEEGCENVLVSRLKDGAW...VTMDEN
U5RP12_9CLOT/5-223IGTITIGQSPRVDVVPEIKSVLGDNIEIVETGAL.....DGL.TRGEI.ESFKIEDN.DYILVSRLQDGTS...VKFAER
AROM_ECOLI/5-224LAILTIGIVPMQEVLPLLTEYI.DEDNISHHSLL.....GKL.SREEVMAEYAPEAG.EDTILTLLNDNQL...AHVSRR
C6WHA6_ACTMD/11-233LGVVTIGQTPRADLTPELRAWL.PGVRIVERGAL.....DGV.TPEQI.TEWAPTEG.DEVLTTRLRDGGS...AIVGHH
W0I3S6_9ENTR/6-226IGTLTIGQAPRPDIAPLLDAALPPQVACIHAGLL.....DGL.DDEAIAARFAVQPG.GAVLTSRLLDGRA...VVMDKA
D5CIT0_ENTCC/5-224LAIITIGVVPVSEVLPLLTEHV.SEQQITHLSLL.....GKM.SREEVMEDYAVEAG.EDPLATLLSDGKL...AHVSRQ
R9VV20_9ENTR/5-224LAILTIGVVPVKEIFPLLAEHV.SEEQITHLSLL.....GKM.DPDEVRREYAVGAG.EHAIPTRLSDDSL...GMVSRE
E6W7U6_PANSA/7-224..TLTIGQSPRSDILPLLQTHL.PAGQVEHAGLL.....DGL.TLAEVEQHYTPVAG.EKVLVSRMLDGQQ...VRLSAH
D4J4L6_9FIRM/6-224IGAITIGQAPRTDITRDILPLLPDYMTLTEYGAL.....DDM.TYEEVMSQFAPSED.DEVLVSRMRDGRQ...AKFTER
D4GS98_HALVD/4-219LGLVTIGQAPRTDVTPDIAAALPPEVDIVEVGAL.....DRFDSAAEVEAAVGPREG.QPVYVSRLADGTP...VTVDRE
D7B4S5_NOCDD/4-224LGVVTIGQAPRTDLTPEITALV.PEATVVERGVL.....DGL.TRDQI.EARPVAPD.DHALTTRLADGTS...VVLGES
Q0K9C3_CUPNH/11-227VAFVTIGQAPRTDVVPQMIADLGLPATVEEFGIL.....DAL.GPQDI.AALAPAPG.EYRFASRLRDGTQ...AVMGKP
R5PRJ6_9BURK/4-224FATLTIGQAPRPDLAPVFNAIAPAGTEVVHAGCL.....DGL.TKAEVDKQFAPVGS.EGLLTSRMLDGTA...VVLGKS
R6RFN0_9CLOT/4-219IGAITVGQTPRTDLIPEIAPILGDSIEIIQMGGL.....DGL.TKEEI.QTMTPAPG.DHVLVSRLKDGSS...VSFGES
R5C719_9FIRM/6-224IGAVTIGQAPRTDITDDIRPMLASNIELSEYGAL.....DPY.SYEEACERFAPSGE.GAVLVSRMRDGRQ...VTMSEK
Q11H78_CHESB/5-216VCFITLGQSPRPELISEVLEHIREPIDYTEIGAL.....DGL.SDGEI...EPPRSLRDTPLVTRLASGEQ...VVVSSE
D8MM34_ERWBE/6-226IGTLTIGQAPRSDITPILDKALPGHVSCLHAGVL.....DGL.DDATIASRFTVIPG.EAVLTSRLLDGRA...VVMGKA
E3F5F1_KETVY/9-222.YFLTAGQSPRPDLIADVTRALPLPIEAHEIGAL.....DGL.SPAAI.AALAPTED.EAQIMTFDAGGQW...ITLSKP
A6T5B5_KLEP7/6-225MAILTIGVVPLAGVLPLLTEHI.REEQIAHISLL.....GEM.TPDEVMAEYAVGDG.EKGLLTLLSNNQL...VMVSRQ
R7D8J2_9FIRM/3-222IGAITIGQAPRTDVTADILHIFDDSLELVQAGGL.....DGL.TKEQI.AEFAPGKD.DYVLVSRLTDGSS...VTFAER
Q8ZRE8_SALTY/5-224LAILTIGVVPMSEVLPLLTEYI.DEQHITHHSLL.....GKM.SREDVMADYAVEPG.DDPLLTLLNDNQI...AHVSRQ
D1AMF6_SEBTE/5-223IGAITIGQSPRIDVIPEMQEILGENVIILEAGAL.....DGL.TKKDI.EKFQPDEN.DYVLVSRLNDGSH...VKFGKS
D1C485_SPHTD/4-219IGLVTIGQAPREDIEATMFPG.GPPVPCQHAGAL.....DGL.DPNAI.AALAPRDG.EIPLVTRLRDGQE...VVVAKE
H3ZPE7_THELN/3-216VGFITIGQSPRVDVVPEIEPYLGD.IEIIECGAL.....DGL.TLEEI.KELAPKEG.EYVLVSRLRDGTQ...VRLSRE
H2IZN8_RAHAC/5-224LATLTIGQAPRSDIMSLLMAHL.PAGSVTHVGLL.....DGL.STEQIEQRYAAAEG.EAVLVTRLLDGSQ...VTMAAH
A8GAI9_SERP5/5-224FATLTIGQAPRNDIMPLLSAYL.PAEQVRHVGLL.....DGL.KASQIDERYTPQAG.EKVLVSRLLDGTQ...VRLAAS
A8MB15_CALMQ/7-221VGFITIGQSPRTDIIPEIMPILGNNIKIIECGAL.....DDL.SLNEI.KKLAPKDN.DYILVTRLRDGTQ...VMLSRS
Q5WKI2_BACSK/4-216IALVTIGQSPRVDMTPEMRPFLGADVEFVEAGAL.....DSL.STEQI.KALAPDPD.EQTYVSRLRNGDS...AKLSKQ
R5XQZ3_9FIRM/3-222IGAVTIGQSPRVDVTKDIMGIFGSSVELIQAGGL.....DGL.TKEEI.KAFAPEKD.DYVLVSRLTDGSS...VTFAER
D7CE98_STRBB/6-233LGLVTIGQAPRADLRPDAEPLL.PGVRLVEHGALDGERFDGP.AERETRRLLAPEPG.EAPLVSRLRDGGS...VVLGHT
Q2RLZ2_MOOTA/5-222VGAITIGQSPRVDVVPEIKEILGDSIEVLEAGAL.....DGL.TREEI.AALAPGPG.DYVLVTRLRDGSS...VRIAEE
F0JK91_DESDE/7-227LGILTLGQSPRTDVEPSLRGILGPDVRFVQRGGL.....DGL.SEESI.RNLAPVEGEPGIETCVLRENGEPKGVCIAKR

PF14669

TOPZ1_RAT/1220-1454EAGMIPDPEHLNYIVKLLHQAQASQQEIS----------AVL-EAKSRLQVRQLRKNWTCDLDSALSEVENCKEKGDWTK

PF01177

A4CJF0_ROBBH/7-221...........INA.KYLDVAQKLEQ..AGAEAIVICANTPHMAYDNVQ.....PK..IGIP.......FLHIADAT...
A2SC58_METPP/7-225...........AAE.QLAVAACGLRD..AGAEGLLIASNTMHRVAPTVQ.....QA..CGLP.......LLHIGDAI...
A8AI88_CITK8/10-228...........PLP.QLLLGVEQLNR..AGASHIVIACNTAHHWYEALA.....QH..SDAP.......LLHIVDAT...
Q04F20_OENOB/8-227...........PLP.FLKEDIQQLNS..LSADFVVITCNTAHYFLPELT.....AI..AKMP.......ILNMPSLA...
Q6FF80_ACIAD/8-224...........PFE.KMREYLKILEN..ANVGCIIIPCNTAHFWFDQLQ.....QQ..THTK.......MISIIEAT...
Q250X9_DESHY/29-245...............PFLRASEFLAH..ADVDAIAWNGTSG..GWTGFDFDRMVCE..KITE.......ATG.IPATTSM
Q2INC6_ANADE/8-223...........ALE.LLLGSLRRLER..AGATLALFAAVTPHRFLAALR.....PR..SPLP.......IADLVGAT...
Q6L2R8_PICTO/8-216...........PVN.AINNGIKYLES..IGIDTIGMACNTAHIWFKEFV.........YKSN.......FLNMIDLT...
Q897B7_CLOTE/8-226...........PLD.ELVKTGERLKN..AGADFLIMPCNTAHYFYDELY.....EK..LNMP.......FINMIEEV...
Q4P1R6_USTMA/36-261...........ETYKALVAASPSSTLALHPASAFLVACFSDHPLVGILR....EKA..PDKP.......AMHLLEAAVIH
A8F5P0_THELT/7-216...........PTL.YLVESVKMLER..EKADFAVFICNTAYAFLDRVQ.....KQ..VNIP.......VLNLPEMT...
Q5LQ34_RUEPO/249-469...........PTL.ALYATCKKLER..AGAQAIAIPCNTAHAFVDRIQ.....KN..LDIP.......IISILTET...
A9BQL6_DELAS/14-243...........PAQ.HLLQGVGRMAA..LGVRSVALACNTAHAWHGQLQ.........ALFPQ....LHVLHIARQA...
Q12P73_SHEDO/7-222...........IYP.ILQRELQYLND..LCPSCILICNNTLHQAFDAIK.....DKLNLSVP.......VFHMADLT...
A9BGM9_PETMO/16-231...........PTP.YLKEGLLTLKK..WGADFLAIPCNTAHYFIDSFI.....SE..IDIP.......LVHIVEAT...
Q97UR3_SULSO/6-223...............ETERAASELST..ILPQIISYACTTG.SLFKGPKHHEEIIQ..RIEK.......IAK.VPATATS
A1SP17_NOCSJ/7-224...........VAE.ILAGAARGVEA..AGADFLLLCTTTFHRVADQVA.....AA..VEIP.......LLHLADVV...
Q5JD97_THEKO/9-223...........PRP.ELIASAKKLES..WGADFIIMPCNTAHFFAETIQ.....RA..INIP.......LVSMIEET...
B5EHN1_GEOBB/7-224...........LIY.LLTAKVKALQK..AGADFAFISANTPHVVFDEVQ.....AK..SPIP.......LISIVTAT...
Q8Y2X0_RALSO/7-225...........LAE.YVLGALRSLAA..GGADIAALTGNTPNIVMDRVR.....PM..SPIP.......VVSAIEAT...
Q6FWC7_CANGA/6-225...........VAE.YLAHAACNLQK..AGADFGVMCGNTPHIVFEKIQ.....GK..TDLP.......LLSMVQCS...
A1TM90_ACIAC/9-232............VAARTHAIAGYLQR.THGIKALVVACNTATAAAIHEVR..ARHA...DLP.......LVG.VEPA...
Q1GTC8_SPHAL/7-224...........AKE.VLIGSAQRLEA..AGATALMIAANSMHKVAEDVA.....AA..ISIP.......LIHIVDET...
Q5JKS2_ORYSJ/89-319...........TALGKLRLRRLLLEK..SGVCCIAMPCNTLHAYHDEIS.....QG..CSVP.......SLHIGDCV...
Q8U0C4_PYRFU/10-224...........RKR.ILINAAKALER..AGAELIALTANTPHIVFDDIQ.....KE..ISVP.......MVSIIDAV...
Q7P1U9_CHRVO/27-245...........VAD.SIVGSLQRLAG..AGAELAVIPANTVHLVVDDIR.....AR..SPIP.......LISILDVV...
Q16BZ8_ROSDO/10-226...........PGP.VLAQMAARLEL..AGAQVLAMPCNTAHLYATQIE.....DA..VGIS.......LLNMPKLA...
Q7W0P3_BORPE/17-237...........PLP.WMRHGIRRLEQ..AGATAIAIPCNTAHVWYPQLA.....QS..ASVP.......VLHIVEAV...
A5G0P7_ACICJ/7-220...........LGA.YLGGLANELAD..AGCEIVAISAVAPHIAISDIT.....RV..ARVP.......LISILDAV...
Q7MS48_WOLSU/7-225...........LEE.KLLQAALELER..LGCQGLAIASNTMHLLAPALE.....GA..LSIP.......LVHIADSV...
A9WE52_CHLAA/2-208............IRDRALACGRWLVD..QGARIVVVACNTATAAAIELL....RRE..LPVP.......VVG.MEPG...
B0JPW0_MICAN/11-224............FIDFIQVNLEHLNK..L.ADCIVIGCCTAHYALPQIS.....EN..LKDK.......LLSLIKIA...
B2UHS6_RALPJ/3-209.............Y.ATACVVAE.HA..GQFDGVVVAAFGD.PGLAGIK.....EL..CNVP.......VVGMTEAA...
B4EC48_BURCJ/3-210...............GLLAEIAQGER..DGCDAYVIACFGD.PGLYAAR.....EL..ARGP.......VIGIAEAA...
I3U2M8_ENTFC/8-225...........PMP.FLLDDIEKQNL..LRPNFIVLTCNTAHYFFEELQ.....AA..TDIP.......ILHMPREA...
I3WGY8_BIFBI/9-232...........PFP.IIADDIDKATA..MGASFIVLTCNTAHYFYDHFQ.....SL..TPVP.......ILHMPRGAVA.
J9ZES5_LEPFM/12-224............ILRFARENVLFLRT..LHPSLIVAACFTVSSQVLPEL...SREF..PDVP.......IVGVLEAG...
MURI_HELPY/3-218............IKQFGLEALDFFKP..HQIKLLIVACNTASALALEEM....QKH..SKIP.......VVGVIEPS...
Q4FL57_PELUB/5-243PRNSKNTKKYNRVLKSLLDGCKSLEK..SGCKFIVIPCNTAHYWYEDLR.....KK..IKIP.......IINMPKEV...
Q5NNC8_ZYMMO/7-224...........KLTTYLMHGVNNLIA..AGADVIALTGNTPHIVFDDLQ.....KQ..SDVP.......LISIVEAT...
Q5ZT55_LEGPH/25-230............VKQYAMQMAKILVE..RRIKALVIACNTATTAALPHL...QSML..TDIP.......VLGVVAPG...
Q74HN5_LACJO/8-224...........FFY.DLKDDVLSQSK..LNPDFFVMPCNTAHYFYDDLA.....AL..TGVP.......FLHMMRIA...
MURI_LACJO/6-213............IISLTRDSVNFLLS..KDVKIIIFGCNTA.TAVAMAT...IQKE..IPLQ.......IIGVVQSG...
Q81LA8_BACAN/7-216............VRQFTWEMTEHLLD..LNIKMLVIACNTATAVVLEEM....QKQ..LPIP.......VVGVIHPG...
Q81R35_BACAN/7-223...........STGEILENAAYSLQK..GGADFIIICTNTMHKVVEKIK.....EN..IHIP.......ILHIADAT...
R5ZKA2_9ACTN/7-237...........KLLATMKECAQALES..LGCAHIAIPCNTSHYFYDQIQ.....SF..TTVP.......IIHMPRESVRY
R7EMK1_9BACE/12-229............VYEFTLQAVTKLFE..MGCHLVILACNTA..SAKALR...NIQM..NDLPRLDPMRRVLGVIRPT...

PF07302

W5W931_9PSEU/4-222-----------LAEGLVAAAVRRAES--AGADVVLLACGG.SFGEIEH.---------.RKP-------LLRTEELA---
D7GS63_9FIRM/4-220-----------YILPRLQLCIDDLEQ--QGVSLILFLCTG.EFPAEFRS---------.NVP-------LIFPDHIL---
A8I8Z9_AZOC5/6-223-----------EVEVRAARQIARFAE--EGVAVTLMACTG.KFPNLPE.---------.DGK-------VIFPSAVL---
A7MLX0_CROS8/5-224-----------KTERALQSVIEVLDN--QGYDVILLMSTQ.RFSGLRAR---------.NAI-------LLEPERII---
E3HTW6_ACHXA/8-227-----------AAEARLAEVMRQADA--AGYDVLVPLCTGTAIAPM...---------.RTL-------VVEPQQVV---
G2NY32_STRVO/21-248-----------AIVPRITDAVARAER--DGAAATLLLCTG.RFPAGRA.---------.RRP-------LLFAEPLV---
B2VIS4_ERWT9/6-224-----------KVERGLQKCILQLEE--QGFETILLLCTG.VFDRLHTN---------.RAM-------LLKPDRIV---
Q89Q90_BRADU/10-227-----------EVERRASQQITRFKH--EGVGVTLMACTG.KFPNLAA.---------.DGL-------VILPSAIL---
R5F3Q4_9CLOT/6-223-----------KLLPLLEERIKQLEE--QGAALGVLLCTG.LFPSIQEG---------.EIP-------IIYPFRLM---
U5RP12_9CLOT/5-223-----------NILLKLQKCIEKLEN--RGVEIIVFICTG.CFPPVFKS---------.NKL-------LIYPQTIL---
AROM_ECOLI/5-224-----------KVERDLQGVVEVLDN--QGYDVILLMSTA.NISSMTAR---------.NTI-------FLEPSRIL---
C6WHA6_ACTMD/11-233-----------HIAPRVRAAVADLEG--AGVDAVYLACTG.EFGELEH.---------.RGP-------VLRPEFMI---
W0I3S6_9ENTR/6-226-----------AVGTAVQEKIHALDA--QGCDIIALLCTG.EFHGLTTQ---------.RAW-------LMAPDLIL---
D5CIT0_ENTCC/5-224-----------KIERSLQAVIEVLDN--QEYDVILLMSTA.PIKGLMAR---------.NAI-------LLEPMRII---
R9VV20_9ENTR/5-224-----------KVERDLQGIIEVLDN--QGYDVILLMSTA.DIRGFVAR---------.NAI-------LLEPQRII---
E6W7U6_PANSA/7-224-----------KVEQGLQQKITALEE--QGYNTILLLCTG.EFGTLKTQ---------.KAL-------LLEPDRII---
D4J4L6_9FIRM/6-224-----------FIRPLVQKKIDQAEA--EGVSAIILFCTG.VFPEFRH.---------.KVL-------FIEPQPLF---
D4GS98_HALVD/4-219-----------SVVELLGARFRDLES--E.VTAIGVLCTG.HFPSFDV.---------.SVP-------VFEPSDLL---
D7B4S5_NOCDD/4-224-----------LVMERLPGLLADLER--E.VDAVLLACTG.AFPELEH.---------.TKP-------LFVPDRMI---
Q0K9C3_CUPNH/11-227-----------VAEAMLARLMTSLDD--GRFDALVPLCTGTALPPM...---------.RTL-------VIEPQQVV---
R5PRJ6_9BURK/4-224-----------AVRKALQEKIHQLEK--AGCSPIVLLCTG.EFEGLTTE---------.KVR-------LIEPDRLL---
R6RFN0_9CLOT/4-219-----------HILPRLEACMDQLKK--DQVSLILFLCTG.EFPDTFQA---------.DVP-------LIFPSKIL---
R5C719_9FIRM/6-224-----------AVIPLVQDCIARAEQ--DGVDATVLLCTG.RFPKLIH.---------.RKL-------LILPQSII---
Q11H78_CHESB/5-216-----------FINRRLDIVTAQIDR--LGHDLLVLLASG.IFRKFET.---------.STP-------LIHGQLAV---
D8MM34_ERWBE/6-226-----------AVGLAVQQKISELAA--AGCQLVVLLCTG.EFHGLHGD---------.GAW-------LIEPDRIM---
E3F5F1_KETVY/9-222-----------RLAARMAAALAQVPV--DQRPLVVILSTG.LLGDFDT.---------.PFP-------TVNAQRAL---
A6T5B5_KLEP7/6-225-----------KIERDVRSAIAMLDR--QHYDVILLLSSE.QLTGFTTH---------.HAI-------LLEPQRII---
R7D8J2_9FIRM/3-222-----------HILPRLQDAINRMED--EGCSLIMMFCTG.SFPETLST---------RKIP-------MIYPCELL---
Q8ZRE8_SALTY/5-224-----------KVERDLQSVVEVLDN--QGYDVIILMSTA.AIKSMAAR---------.NSI-------LLEPLRII---
D1AMF6_SEBTE/5-223-----------YIIPRLQNCINSLEE--QGAELIIVICTG.YFGNLLTS---------.KVP-------LIYPQKIL---
D1C485_SPHTD/4-219-----------SVLPLLAGAVKRVVA--DGARVVVVLCTG.EFPGLTA.---------.PVP-------LVFPDRVL---
H3ZPE7_THELN/3-216-----------KIVKRLQECIKKLEK--E.VDIIGVLCTG.EFPELTS.---------.KKL-------LVEPSLLL---
H2IZN8_RAHAC/5-224-----------RVERGLQEKIALLEA--LGCMTILLLCTG.QFHHLQAN---------.NAL-------LLEPDRII---
A8GAI9_SERP5/5-224-----------RVELGLQQKINALEA--EGCEVILLLCTG.EFGQLHAQ---------.QAL-------LLEPDRII---
A8MB15_CALMQ/7-221-----------KIIDLMQKCIEKLEK--D.VNLIGLLCTG.DFPELKS.---------.NIL-------MIEPSKLT---
Q5WKI2_BACSK/4-216-----------KLLPHLQAELQKVEK--H.VSSSIIVCTG.HFPTIQH.---------.EKP-------LLFPDKIL---
R5XQZ3_9FIRM/3-222-----------FILPRLQAAIKKMEE--EGCALVMMFCTG.SFPESLST---------EKIP-------LIYPCDIL---
D7CE98_STRBB/6-233-----------ALVPRIERAVAHAER--DGAAATLLLCTG.HFPAVRA.---------.NRP-------LLFAEPLV---
Q2RLZ2_MOOTA/5-222-----------KILPLMQARIDGVVA--AGAEAVLLLCTG.EFPPFSC.---------.RRL-------ILKPQLIL---
F0JK91_DESDE/7-227-----------HLLPRLIAAGRELET--L.CDIFFLLCSG.EFPALKHA---------.VPR-------LIEPITFI---

PF14669

TOPZ1_RAT/1220-1454-------------LGNLYISIKMGCE--EFADFQRFCACVAETLTEDYK------EERPGVP-------FCEFAETV---

PF01177

A4CJF0_ROBBH/7-221.........GK.....EAER.....LG-LKK...LGLLGNRPTMTGS--FISGFLKSNYH...MEV.LIPEAENIG....
A2SC58_METPP/7-225.........GA.....ALRA.....AG-LTR...IGLLGTRFTMEQD--FLRDHLRQRHG...VEM.RVPGEADRA....
A8AI88_CITK8/10-228.........LA.....VFEGK....EK-PRR...VGLIATQGTLDAG--WFQHGFAS.MG...IESVQPTPEELRQ....
Q04F20_OENOB/8-227.........VQ.....ACKKR...TAG-TLK...ISILATDGTIASG--LYQEKISA.QS...DQA.IIPDKELQI....
Q6FF80_ACIAD/8-224.........VR.....FIQK.....SN-AQE...ICILATSATINTE--LYQKELAN.HQ...IKF.TLPELEIQQ....
Q250X9_DESHY/29-245......LAMLE.....AFEE.....NK-VKT...LHMVTPYIPAIDE--LIAKQFEEKCG...Y........QVINSRGL
Q2INC6_ANADE/8-223.........CD.....DVRA.....AG-HRV...VGLVGTRFTVSEP--FFREALEA.AG...VRV.VVPDEAGTD....
Q6L2R8_PICTO/8-216.........AS.....VLKK.....SG-FKN...VLLLSTNATVSSG--IYTGKLRD.YN...INT.VIP...DQD....
Q897B7_CLOTE/8-226.........GK.....YIVTK....HG-KIK...VGLLATLGTYQGK--IYERYCKE.LG...LDI.IIPSKEVRQ....
Q4P1R6_USTMA/36-261......SLCVG.....H..........-..K...FGILT.TAQSMVS--DLECGVRKVLG...G.....NSDRFVGTHAT
A8F5P0_THELT/7-216.........LR.....KLKS.....KG-IEE...IWLTGTRGLLNSR--VYQREAEK.IG...LTL.KIPEERLQE....
Q5LQ34_RUEPO/249-469.........AR.....FIGAL...HPE-IGK...VAVLATSGTIQSG--LYQSALRD.QG...LDP.VLPDAGMQE....
A9BQL6_DELAS/14-243.........AL.....HLQA.....GG-AQQ...AIVLATQGTYDSG--LYDAALAE.CG...ITA.LQPDAQGRA....
Q12P73_SHEDO/7-222.........AQ.....HVYQ.....KG-HKK...VLLTGTQYTMESG--YYSNKIAA.HG...IEV.IVPALEERI....
A9BGM9_PETMO/16-231.........IK.....KAKI.....FS-PEG...AWVLSTLATKKTE--LYGKYAKK.EN...YNL.FHPDWDFMK....
Q97UR3_SULSO/6-223......GSVIN.....ALRR.....LD-IKR...LVLLTPYIEEVNK--KEIEFFSKN.G...F........EIVKSAGM
A1SP17_NOCSJ/7-224.........AD.....ACKA.....ER-LDS...VGFLGTTFAMSRS--FFTDRIAA.HG...LTV.HVPETRHHE....
Q5JD97_THEKO/9-223.........AK.....KIES.....MG-LRK...VGLLATDGTIKGM--VYHRALLK.RG...IHI.AVPNKKDQG....
B5EHN1_GEOBB/7-224.........LE.....KAKE.....LG-VKR...VGLLGTKFTMEEN--FFAAPFSA.AG...ISV.VIPQPADQQ....
Q8Y2X0_RALSO/7-225.........CA.....EAQR.....RG-VRR...VGLLGTVFTMTNT--FFKVPFED.RS...IQV.VVPDDAQIA....
Q6FWC7_CANGA/6-225.........LD.....VASA.....MG-LKR...LALLGTKFTMQND--FFKRPFEM.AG...ISI.YTPSPVEQE....
A1TM90_ACIAC/9-232.........LK.....PALSL....TR-TGR...VGVIGTRGTLSSA--KFQRLRASLQGPVEF................
Q1GTC8_SPHAL/7-224.........GE.....KMKA.....DG-VKA...AAVIGTRNVMTEA--WFRQRLVR.HG...LTL.APYDATRAD....
Q5JKS2_ORYSJ/89-319.........VK.....ELKSANLKPVE-YGSNVCVGILCTDNTLNAK--CYLNKLES.QG...FEVLLPDKASLEH....
Q8U0C4_PYRFU/10-224.........AE.....EILS.....HG-LKK...VLLLETKTTMSSG--FYVNALKN.KG...LEV.VVPNEEEQE....
Q7P1U9_CHRVO/27-245.........AD.....ACAA.....RG-LKR...VAILGTRWTMARR--LYQAPLAA.RG...IEE.MIPDEEQQV....
Q16BZ8_ROSDO/10-226.........CA.....QAAQ......G-MKRGGIVGILASPATNSSG--LFGNFLAR.HE...VQSAFPENED.......
Q7W0P3_BORPE/17-237.........LD.....DLRRQ...GIH-AGR...VGLLATATTLRLG--LYQHEMLA.QG...YEPVVPPVDLIDG....
A5G0P7_ACICJ/7-220.........PA.....GLAA.....AG-TDR...VAVFGNRAVMHTR--VFGAV....AK...QRD.ISLDRDDLD....
Q7MS48_WOLSU/7-225.........GE.....ESSL.....KG-YKK...LALLGTLFTMEKD--FYASRLQERFD...LEV.ITPAKEERN....
A9WE52_CHLAA/2-208.........VK.....PAVAA....TR-NGK...VAVLATSGTLASD--RFRSLVQAYAAGVEV................
B0JPW0_MICAN/11-224.........DQ.....ELQE......Y-NEP...TLLLASTGTYQKK--LFQEGCTTA.D...LII..SLSESDQK....
B2UHS6_RALPJ/3-209.........LA.....SACL......L-GQR...FSIIA.ISNRIQA--WYRECVAAN.G...L......SSRLASV..R
B4EC48_BURCJ/3-210.........MH.....AA.S.....VL-APG...FSVVT.TLARTCG--MAWHLAERY.G...M.......KRFCR....
I3U2M8_ENTFC/8-225.........AN.....ELVRQ....HT-TGR...VAILGTEGSMKAG--IYEREVKNL.G...FET.VIPDTALQE....
I3WGY8_BIFBI/9-232.......HMAG.....QYPK.....ER-FHR...VGFLGTMGSRASG--VYRQAVEEA.G...YTF.VEPDDELQE....
J9ZES5_LEPFM/12-224.........AR.....AACRL....TR-TGS...VGVLATEGTISSQ--AYPAVIGEMTA............HSVR....
MURI_HELPY/3-218.........IL.....AIKRQV..KDK-NAP...ILVLGTKATIQSN--AYDNALKQQ.G...Y........LNVS....
Q4FL57_PELUB/5-243.........FI.....QTKKS...CKK-NSK...IGLLATEGTLKTE--IYDKIFKK.DY...VLI.KPLSNLQTS....
Q5NNC8_ZYMMO/7-224.........CD.....EVKR.....QN-ITK...VGLLGTRFTMEAD--FFKKPLIAN.G...MSV.ITPQPKEID....
Q5ZT55_LEGPH/25-230........AAA.....AVSA.....TK-NHR...IAVLATETTIASR--AYHDLIIKN.....L......PEAVVS....
Q74HN5_LACJO/8-224.........VH.....KFVDD...FPK-EEK...IGLIATEGSIYDH--LYVDELERV.G...KKA.ELGGPEIQP....
MURI_LACJO/6-213.........AL.....AAART....TE-TKN...VAVIGTKATVASH--SYLKEIQYR.DP.EI.....KVSEFAQ...P
Q81LA8_BACAN/7-216.........SR.....TALKV....TN-TYH...VGIIGTIGTVKSG--AYEEALKSINN............RVMV...E
Q81R35_BACAN/7-223.........AK.....EIKR.....KD-IQT...VGLLGTKYTMEQD--FYKSRIEEN.H...IKV.VVPSEKDRD....
R5ZKA2_9ACTN/7-237ALAGAVMGECEFDPNLSMPA.....EP-VHK...IGIMGTDGTVGAG--VYGRECKAA.G...VEV.VYPSEKRQN....
R7EMK1_9BACE/12-229.........VE.....CIGNI....TQ-SRH...VGVLATAGTIKSE--SYPLEVHKLFP..DI........KV......

PF07302

W5W931_9PSEU/4-222---------QH-----AVSGL----AK.GLR---IGVLRPLADQVEP..ARRAWCRVLGTD.QLAT--------------
D7GS63_9FIRM/4-220---------KG-----LIPAI----GV..KN---LSVIIPTKEQEAQ..MPGKWKDCCD...SLHV--------------
A8I8Z9_AZOC5/6-223---------HK-----LVEAV----LP.KGR---LGVFSPLAEQSAL..IHKKWERDGV...EVVG--------------
A7MLX0_CROS8/5-224---------PP-----LVASI----VD.GHQ---VGVIVPIPELMDI..QAQKWQVLEN...PPLY--------------
E3HTW6_ACHXA/8-227---------DH-----LVAGL----AEHCRK---VGLVVPLEAQVD......AFHMVVPLSCETLV--------------
G2NY32_STRVO/21-248---------QQ-----AVAAT----VG.TDP---VGIVCPHPDQAED..VSQRWAELLPG..RVQA--------------
B2VIS4_ERWT9/6-224---------PP-----LIATI----VG.DLQ---VGVVVPVVEQTAE..QASKWKVLSH...PPCY--------------
Q89Q90_BRADU/10-227---------HN-----LVEAV----LP.KGR---LGVFSPLPEQTVL..IDKKWQRDGV...EVVG--------------
R5F3Q4_9CLOT/6-223---------ET-----VLPCF----SR.RGR---VGIVTPDEKQKGL..CLEKWSSAMA...HVAV--------------
U5RP12_9CLOT/5-223---------HS-----VVPNL----AS.NNK---IGVFTPLCNQIRQ..TYDKWSESGK...DIEV--------------
AROM_ECOLI/5-224---------PP-----LVSSI----VE.DHQ---VGVIVPVEEMLPV..QAQKWQILQK...SPVF--------------
C6WHA6_ACTMD/11-233---------GH-----AVAAI----AAGLTT---VGVLVPLEEQKHH..PDTKYAPLDA...EVVV--------------
W0I3S6_9ENTR/6-226---------PA-----TQTAL----VG.QRR---AGILVPLASQIDS..EKEKWRGLAV...APVF--------------
D5CIT0_ENTCC/5-224---------PP-----LVASI----VD.GHQ---VGVIVPIEELMDN..QEAKWHVLEK...TPLY--------------
R9VV20_9ENTR/5-224---------PP-----LVASI----VD.GHQ---VGVMVPIPELMAQ..QKKKWQVLEN...EPYY--------------
E6W7U6_PANSA/7-224---------PP-----LVGAI----VH.GHK---VGIVVPVEEQIAE..QASKWRNLGT...PPCF--------------
D4J4L6_9FIRM/6-224---------HA-----IAAKL----AG.NQK---IGILVPEPDQVEQ..AYHTWGKSGI...PVEV--------------
D4GS98_HALVD/4-219---------SA-----WVSAI----LN.GGT---LGVIMPKEEQEAM..TFEKWADY.....DLVT--------------
D7B4S5_NOCDD/4-224---------AF-----GAAAL----LGDTGR---LGVVCPLPEQRRD..TEAKFGRRLPAGARVLT--------------
Q0K9C3_CUPNH/11-227---------DH-----LTVAL----AQGCKR---LGIVLPLEAQVS......SFHLIQPVPCELRV--------------
R5PRJ6_9BURK/4-224---------PP-----VFAAL----LN.PLQ---VGVMVPLIEQAQS..ELNKWKGLDK...PPVF--------------
R6RFN0_9CLOT/4-219---------TS-----IVSAI----HP..HR---LAVIAPVKEQLPQ..MQTKWAGCAG...SVYG--------------
R5C719_9FIRM/6-224---------HS-----LVQKL----TL.GQS---IGLFVPDRAQIAQ..VKEWFHESQI...PFVP--------------
Q11H78_CHESB/5-216---------DE-----WIASF----ILGTAQ---LGVVFPLRKQASDPVTLHDYGILIQ...NYQT--------------
D8MM34_ERWBE/6-226---------PP-----TLNAL----VG.DRQ---AGILVPLASQIAS..EQQKWHNATR...PPVF--------------
E3F5F1_KETVY/9-222---------ES-----TISAL----AEMGEQ---IGIIQPLPHQAA.......YEAIPALSSYKVE--------------
A6T5B5_KLEP7/6-225---------PP-----LVASI----VD.GHQ---VGVIVPVEEIMPM..QRQKWLSLEK...SPYY--------------
R7D8J2_9FIRM/3-222---------NR-----LVPLM----TK.KSD---IICMTPSPLQTEQ..CENKWKKYVD...HVKA--------------
Q8ZRE8_SALTY/5-224---------PP-----LVASI----VD.GHQ---VGVIVPVAELLAA..QEKKWQVLQM...PPVY--------------
D1AMF6_SEBTE/5-223---------YS-----LVPNF----SV.NGK---IGVIVPEEDQIDQ..MGKKWEETGL...EVSA--------------
D1C485_SPHTD/4-219---------RG-----TVDAL----LP.DGI---LGVLMPHPGQGPL..MERKWAAPGR...SLRC--------------
H3ZPE7_THELN/3-216---------LK-----TVESL----GV..SK---LGVVVPDPDQIEM..TKRKWSNIAD...TIKV--------------
H2IZN8_RAHAC/5-224---------PP-----LIGAM----VG.QHR---AGIVVPVESQVVE..QANKWRKLAK...APCF--------------
A8GAI9_SERP5/5-224---------PP-----LISAI----VS.QHR---VGIVVPVAEQISQ..QASKWQLLAT...PPCF--------------
A8MB15_CALMQ/7-221---------MN-----VVKSM----NV..KK---LGIFVPDKSQINL..IKNRWLNIVN...DVTV--------------
Q5WKI2_BACSK/4-216---------CH-----FVQAV----IG.DGT---LGAIVPLEEQIQQ..LAGKWGEL.....PLVS--------------
R5XQZ3_9FIRM/3-222---------DR-----VVPLL----TK.SSH---IICLTPSPLQEEQ..CAAKWKNYVQ...KVSV--------------
D7CE98_STRBB/6-233---------LR-----GVAAA----VG.ADP---VGIVCPHPDQAED..AVRRWSDVLSG..EVRA--------------
Q2RLZ2_MOOTA/5-222---------HH-----FTAAV----AT.GRR---LGVIVPDAGQVEE..TRKRWAGVGS...DLAV--------------
F0JK91_DESDE/7-227---------RC-----VVAAV----AR.HSH---LCVIGP.ESDMPA..APAQWQPYAA...RVST--------------

PF14669

TOPZ1_RAT/1220-1454---------SKDPQYSEVDK-----TL-LGR---IGISAVY--------FYHRLLLWSKGRKVLDI--------------

PF01177

A4CJF0_ROBBH/7-221KAHKFVS..EELT....QGA.FTPP..AREFFTGQME....LL....R.ARGAEGIILGCTELPILLKED......D...
A2SC58_METPP/7-225TLQQLIF..DELC....RGI.VRDA..SRQATLTIVD....RM....A.ADGAQGVVLGCTELGLLLDPA......A...
A8AI88_CITK8/10-228WFVPGCY...AVK....RGE.LRTGGELLSLQAQALR............DRGAERLVLACTEVPVALAEVTSPHLAV...
Q04F20_OENOB/8-227QVMKFIY..QDIK....QNN.RIEADKYHHLVEKLLI............KQKCDYVILGCTEFSVAQEREPYISDR....
Q6FF80_ACIAD/8-224LVMQSIY...SYK....SGN.IEEAKNIMINIINLYE............YNPARKFLLACTEIPLILEDWIIEKPEL...
Q250X9_DESHY/29-245NQT.......VNRS...FSL.VTPE..QIDGMCKEVS............VDPADGISIICTNLRST.WQIEQLERDY...
Q2INC6_ANADE/8-223YLDALIF..GPLA....RGE.KTPE..MKGELAAIVG....RM....AGRAPLDALVVACTDLMDLMGTE..........
Q6L2R8_PICTO/8-216IVMKSIH...YVK........VNDTKMARETIEPVIN..........GHRNEVDALLLACTEMPVIISEKTYNIP.....
Q897B7_CLOTE/8-226KVSDAVY...IVK....SGQ.RNFTKEFAMDMLKEFN............EKDVNAVILGCTELPLIFQPLENDLKDF...
Q4P1R6_USTMA/36-261GL........GVVE...LQT.GNRD..VVEHKLKAGA....RQ....LAANGADVIVLGCAGMT...GFESLVRLACDEV
A8F5P0_THELT/7-216SLMQIIY...TVK....AGQIKKASLIWFSDVEPYLD................GHVLLGCTELPVVAKSKRLH.......
Q5LQ34_RUEPO/249-469MVMEVIYGPSGVK....AGFTTGRCAAQLAQVIAAMT............GQGAQAAILGCTELPLVHLPAPAAIR.....
A9BQL6_DELAS/14-243RLMQGIY..DGVK....QGD.MDLA...ARCFGEVLA....PL....LQRHGDVPVIMGCTEIPLALPQSPLARGAG...
Q12P73_SHEDO/7-222HI.QSMQ..QSIA....KGH.ATEQ..FTAAFEKILA....NY....L...DCDAVITACTELPLVITPT......I...
A9BGM9_PETMO/16-231KIQRVID...MVK....MGN.IEESAKDLKPLLENLW............KAKNVPIIAGCTELPIAYKATKLPKDL....
Q97UR3_SULSO/6-223GIR.......ENIK...IGQ.VTPE..EVYNFAVNVL.........RNVKGDYDGVFISCTNLRTF.EILSRLEKET...
A1SP17_NOCSJ/7-224TLNRVIY..DELV....HGK.VLDS..SRRTVVGLVD....EL....W.DAGAGGVILGCTELELLVHQA......D...
Q5JD97_THEKO/9-223LVMKAIY..EGVK....AGN.LELGRELLLKVAKKLE............RRS.EGIIAGCTEVSVVLKSEDLNVP.....
B5EHN1_GEOBB/7-224YIQEKLM..TEIE....LGV.FKDE..TRDGLLAVIG....RM....KEQEHIDAVILGCTELPLILLKD......E...
Q8Y2X0_RALSO/7-225QIQHKIE..SELE....HGI.VTDE..TRDAFIAIIK....DL....QTREGIDQVALACTELPLILSDQ......T...
Q6FWC7_CANGA/6-225TIHQKIV..GELE....NGI.VTPD..TKSTLLTIIN....GM....IKEHGLDGVILGCTELPLILNQR.......D..
A1TM90_ACIAC/9-232.VVQPCDGLAHAIERSTADT.LPD.DPATAEIRALCARYMAALGPFGAAPGEIDTLVLGCTHYLFAEDALRAHTGPQ...
Q1GTC8_SPHAL/7-224EIDRIIY..EELM....LGK.VNEA..SRRTMKTFIT....DI....A.KQDIQAIVLACTELVMLVDPD......A...
Q5JKS2_ORYSJ/89-319TVLPAIGAFR.......RGD.MEGARNLLRISLQVMF............VRAVNTIILASDDFVGILPDDDPLLKK....
Q8U0C4_PYRFU/10-224ELNRIIF..EELA....FEN.L..K..SKRWIIDLIE....RY....AKEEGVEGVILGCTELPLAVKRG......D...
Q7P1U9_CHRVO/27-245VIQRAIF..EELVP...TGR.ASAA..TLAALLEVVE....AM....K.AQGCDGVALACTELPLVLDDA......N...
Q16BZ8_ROSDO/10-226GILASIR...RIK....KSGPTQTDITLLEREAASLV............RRGAERVIIGCSEFSLVSERIRCPVP.....
Q7W0P3_BORPE/17-237LCAQSIR...LVK....QNL.LPQALPPALACIDSLR............AMGVDAIVLGCTELPLALPHALRAELGV...
A5G0P7_ACICJ/7-220WVHNTYA..EIAI....HGK.RATQPEMTEFSRLANR....LL....Q.RKNAQAILLAGTDLSSFYAEHQP........
Q7MS48_WOLSU/7-225LVHECIY..RELV....NNI.FTED..SRRDFIQIIH....GL....K.ERGAEAVILGCTEIPLLLEGA......S...
A9WE52_CHLAA/2-208.YPLACPDLVAQVE...AGE.LQSD..QTRNLIEQHL..........ATVPEVDVIVLGCTHFPPLKPLIATCAGSH...
B0JPW0_MICAN/11-224LIHEMIY..KVLK....RGH.DPLS..ILRDIEALLE............KYNTRSYISGCTEFHLLTKSL.KLKGID...
B2UHS6_RALPJ/3-209SLQQ......PLRD...IGS.VQED..HAARLEELSL....QA....VREDGADVIIVAGAPLA...GLARTLKDRI...
B4EC48_BURCJ/3-210NV.RATD..VAVLE...LDR.PGSA..ARRIIVDECR....RA....LDEDGADAIVLGCAGMA...EFAHEIEQQI...
I3U2M8_ENTFC/8-225KINYLIY..HEIKE...SDY.LNQE.LYYEILEEAVE............RLNCEKVILGCTELSLMHEFAEDNH......
I3WGY8_BIFBI/9-232RITSLIY..DDVKG...TGD.LNLQ..RYESVLQAML....DP....AGTCRCDTLMLGCTELSVLNEAFPLPQ......
J9ZES5_LEPFM/12-224VYGQACPLFAPMVE...EGV.TEGP.IAELVARKYLE...PFL....SVYREVDTIILGCTHYPPLRRTLEAILPD....
MURI_HELPY/3-218HL..ATSLFVPLIE...ESI.LEGE.....LLETCMRYYFTPL......EILPEVVILGCTHFPLIAQKIEGYFMEHFA.
Q4FL57_PELUB/5-243SVNKTIK...HVK....MGN.IKLA...EKTIKPAIK....YL....I.KQKCKKIILGCTEIPIAIFAYKSLQNAK...
Q5NNC8_ZYMMO/7-224YIANKID...SELE...KGI.FSQN..TLSEFISIIS....RM....RDSDGIEAIILGCTELPLLFKNT.....EF...
Q5ZT55_LEGPH/25-230S..RACSVLVALAE...EGM.VTNA.VAREALKHYLD...........DFSDEDAVLLGCTHFPVFKPLLSSLLPKD...
Q74HN5_LACJO/8-224MVNELIY..RDIKE...KGI.VDHD..LYHKILKTMH...........DEYGCNVILLGCTELSLAQEKAPDHP......
MURI_LACJO/6-213KLA.......PLA....EED.PDED..TKNAVVSESL...TPL.....KNADYDTLVLGCTHYPLLRDEIVAVVGQD...
Q81LA8_BACAN/7-216S..LACPPFVELVE...SGN.FESE.MAYEVVRETLQ....PL.....KNTDIDTLILGCTHYPILGPVIKQVMGDK...
Q81R35_BACAN/7-223KVNEVIY..TELC....LGK.ITSQ..SREYYKRVIE....NL....I.QEGAKGIILGCTEIGLLIKQE.....DV...
R5ZKA2_9ACTN/7-237DVMSLIY..DDVK....AGR.EPDM.DKFDRVMWEFA............RSGCDRVILACTELSVLQKYREMPEI.....
R7EMK1_9BACE/12-229.SGEACPLWVSLVE...NNE.AQGE.GTDYFIRKNIG....NL...LAKDTQIDTVILGCTHFPLLLPKIQQYMPD....

PF07302

W5W931_9PSEU/4-222AVVNPFD----------.AA-P....GELAAAVAGIA------------D.QCDLVVLDCFGFDEQMRAVAAGVF-----
D7GS63_9FIRM/4-220TSVSPY.----------.GD-P....LAVFAAAKEIP------------A.DTDLILLDCIGYTIEMKERIQALT-----
A8I8Z9_AZOC5/6-223VTLQPG.----------.SD-E....AAVDAAATEMA------------ALQPDLVVMDCMSYSSANKARVRHTY-----
A7MLX0_CROS8/5-224ALANPFY----------.GT-E....DELVGAGRDLL------------ARGADVLLLDCLGFHQKHRDLLQKAL-----
E3HTW6_ACHXA/8-227VHASPYE----------.AD-AAQAARNFEQAGRELA------------..SCDLIVMHCMGYAERMRQAVAQAS-----
G2NY32_STRVO/21-248ATADPY.----------.GP-AELVLEDIAAAARTLA------------DRGSSWLVLDCIGYTEQMRTAALRAA-----
B2VIS4_ERWT9/6-224AVASPYQ----------.AG-D....GSLLDAALSLQ------------EQGAEVVVLDCIGYQQRHRDRLQKIL-----
Q89Q90_BRADU/10-227ITLRPG.----------.SS-D....AVVDEAARTMA------------DLEPDLVVMDCISYTSANKARVRTAY-----
R5F3Q4_9CLOT/6-223TVCNPY.----------.DR-G....QNLEQAAIDMR------------EVDPDFIVLDCIGYNKEMKHKMEQLT-----
U5RP12_9CLOT/5-223IAASPY.----------.ES-I....EKIKKAALDMK------------EKNVDVIVMDCIGYNLKMKNMVRDIT-----
AROM_ECOLI/5-224SLGNPIH----------.DS-E....QKIIDAGKELL------------AKGADVIMLDCLGFHQRHRDLLQKQL-----
C6WHA6_ACTMD/11-233AVATPYA----------.GP-PEAVAEGLRAAAAEFK------------AAGAQLIVADCIGYTQAMRAVLVAEL-----
W0I3S6_9ENTR/6-226AVASPYT----------.AP-E....EEVAAAARSLA------------QQGAEVILTDCMGYTAWHKDICAREA-----
D5CIT0_ENTCC/5-224ALANPFW----------.DS-E....AKLIAAGKELL------------ERGADVLILDCLGFHQHHRDLLQKAL-----
R9VV20_9ENTR/5-224VLAHPYL----------.AT-E....QELIAAGKELI------------ERGADVLMLDCLGFHQYHRDLLQKAL-----
E6W7U6_PANSA/7-224AVASPYL----------.AQ-Q....ADLVDAGLSLQ------------EQGADVVVLDCIGYHQKHRDFLQKML-----
D4J4L6_9FIRM/6-224TSASPY.----------.LD-F....DKVVEAASFFK------------GKNLAFICTDCMGFTMEMKHQIQEVT-----
D4GS98_HALVD/4-219AAGSPY.----------.AD-D....DEVLAAAADIG------------T.DADLIVMDCMGYTPEMKATVRELT-----
D7B4S5_NOCDD/4-224DVCSPYT----------.GT-P....DGLAAAARRLA------------DAGADLLALDCVGYTEEMRARAAAAS-----
Q0K9C3_CUPNH/11-227THASPYT----------DAS-T....DRFAQAGETLR------------..GCDLVVMHCMGYTEAMRAEVARHA-----
R5PRJ6_9BURK/4-224AAASPYT----------.AS-K....EELQEAARKLA------------HQGAEVIVLDCMGYSKTLRDICAEAV-----
R6RFN0_9CLOT/4-219LAASPY.----------.DG-I....EAVAAAARSIP------------S.DADLIVLDCIGYTVEMKERVQALT-----
R5C719_9FIRM/6-224VIASPY.----------.QE-A....HLMGERAQALN------------GQNLSCVLLDCMGYGCQMKKDIQQAC-----
Q11H78_CHESB/5-216VAYS...----------.GE-A....SRIDETALLLR------------..DVDFILMHSVGYTKEMAQQLASES-----
D8MM34_ERWBE/6-226AVASPYT----------.AT-E....EEVAAAARSLA------------DRGAEIILTDCMGYTGWHQAICKRRV-----
E3F5F1_KETVY/9-222KIAARM.----------.GD-R....TALEQAGRALS------------..HCAFIVLNAVSYSAADADIVRAAS-----
A6T5B5_KLEP7/6-225ALANPFT----------.GS-D....SELLTAGKTLL------------EQGADVLVLDCLGYYQHHRDVLQKAL-----
R7D8J2_9FIRM/3-222VSASPY.----------.GE-W....DALEKAAEEIK------------NSEADLIVLDCIGYTQEMKKMFAEKT-----
Q8ZRE8_SALTY/5-224SLANPVH----------.GS-E....QQLIDAGQALL------------DQGADVIMLDCLGFHQRHRDILQQAL-----
D1AMF6_SEBTE/5-223AAGSPY.----------.KG-I....EEVKMAAQKLK------------TENVDVIVLDCIGYNKKMKLAAEEIT-----
D1C485_SPHTD/4-219AAASPYT----------.GA-.....AELGVRAEELR------------SAGAQLIVMDCMGYTAEMKQAVATA.-----
H3ZPE7_THELN/3-216QSVSPYL----------.GE-K....DELIRAAQELK------------..DCDLIVLDCIGYNFNAKKLVKKIT-----
H2IZN8_RAHAC/5-224AVASPYL----------.SD-D....EALTQAAMQLA------------EQGAEVVVLDCIGFNRHHADVLKKHL-----
A8GAI9_SERP5/5-224AVASPYL----------.AD-D....AVLELAASELQ------------RQGAQVVVLDCIGYHRQHRDFLQARL-----
A8MB15_CALMQ/7-221VSSSAYI----------.NT-I....DKFKELSKQLI------------..DTDLIVLDSFGYSITIKKTVAEIT-----
Q5WKI2_BACSK/4-216EAATPY.----------.AS-.....SDIEGAAAALK------------QQGATLLVLDCMGYTNAHKQRAQAAT-----
R5XQZ3_9FIRM/3-222VAASPY.----------.GD-W....GELEKAAEEIS------------GMEGDLIVLDCIGYTQEMKKMFAQKT-----
D7CE98_STRBB/6-233APANPY.----------.AP-PEQALDEVAAAARALA------------EAGSSWIVLDCIGYTERMREAAVRAA-----
Q2RLZ2_MOOTA/5-222EAASPY.----------.GP-V....DAIWEAAARLQ------------AWQAELIVLDCIGFNMSMKREINRRT-----
F0JK91_DESDE/7-227AVSSPY.----------.DG-K....ERLSEAARTAK------------ASGAKYILLDDMGFTEEQRQLVRSVS-----

PF14669

TOPZ1_RAT/1220-1454-LYELKIHFTSLKGLTGPEK-IAPRCQIVNVAAEIFI--------KSGSLDGAIWVLRGESEWITSTPLWPCDRA-----

PF01177

A4CJF0_ROBBH/7-221..IDMPLLATTHLHVQMAV---
A2SC58_METPP/7-225..LPLPGFDSTWLHVQQAL---
A8AI88_CITK8/10-228......SIDPAEALAQQCA---
Q04F20_OENOB/8-227......VIDAQQVLANTAV---
Q6FF80_ACIAD/8-224......FIDATDVLIRNAI---
Q250X9_DESHY/29-245...GITVYDSTAVTVWKTL---
Q2INC6_ANADE/8-223....VRLLDPIDSHLRLAL---
Q6L2R8_PICTO/8-216......VIDSDEALAAALI---
Q897B7_CLOTE/8-226..E...FISSTDILAKETI---
Q4P1R6_USTMA/36-261GCTGVKVVDGAKAGLQILA---
A8F5P0_THELT/7-216......LIDVNDEWAKIVI---
Q5LQ34_RUEPO/249-469......LIDPTEVLARACV---
A9BQL6_DELAS/14-243......LVDPAWILAQALA---
Q12P73_SHEDO/7-222..TQLEIVDPMAIQCDAAF---
A9BGM9_PETMO/16-231......IISSLEALAEECI---
Q97UR3_SULSO/6-223...KKPVISSNSATLWETL---
A1SP17_NOCSJ/7-224..ADIPVFPCTTLHVAAAL---
Q5JD97_THEKO/9-223......LIDPMDVIAERAV---
B5EHN1_GEOBB/7-224..FGIPFLNTTAIHVESVV---
Q8Y2X0_RALSO/7-225..SPVPCLDTVEIHVRALI---
Q6FWC7_CANGA/6-225..FSIEVLDIAKEHINAIV---
A1TM90_ACIAC/9-232....VRLVETGEPVARQTR---
Q1GTC8_SPHAL/7-224..NLLPIYDTTRIHVAAGV---
Q5JKS2_ORYSJ/89-319......CIDPMDALVRETI---
Q8U0C4_PYRFU/10-224..VSIEVFDSAEIHIKKLI---
Q7P1U9_CHRVO/27-245..CGVPAIDTTLVLAEAAL---
Q16BZ8_ROSDO/10-226......ILDTLDVLVSEIV---
Q7W0P3_BORPE/17-237..A...MTDSIDALALAGL---
A5G0P7_ACICJ/7-220...DFPHIDLAQLHIDQIV---
Q7MS48_WOLSU/7-225..SPLPLLDTMELHVGSIV---
A9WE52_CHLAA/2-208....VTVIDTGPAVAAQT.---
B0JPW0_MICAN/11-224...SIKAIDPLSTIAQ...---
B2UHS6_RALPJ/3-209...PVPVVDGVSSAIRHC.---
B4EC48_BURCJ/3-210...GAPVVEGVTAAVKWA.---
I3U2M8_ENTFC/8-225....YPVIDAQSILADRT.---
I3WGY8_BIFBI/9-232....LPIIDAQAVLVEDT.---
J9ZES5_LEPFM/12-224....IVFVDPGQELAEEL.---
MURI_HELPY/3-218LSTPPLLIHSGDAIVEYL.---
Q4FL57_PELUB/5-243..VSKLYLDPNLILANSCM---
Q5NNC8_ZYMMO/7-224...TITPLDTMEIHINAL.---
Q5ZT55_LEGPH/25-230....VAIVDSAQATA....---
Q74HN5_LACJO/8-224....YNVIDPQSIIAD...---
MURI_LACJO/6-213....KKIVDPADQVAQY..---
Q81LA8_BACAN/7-216....VQLISSGDETAREV.---
Q81R35_BACAN/7-223...SVPIFDTTHIHAVEA.---
R5ZKA2_9ACTN/7-237......TLDAMDVLVRE..---
R7EMK1_9BACE/12-229...GITTVTQGELVADSL.---

PF07302

W5W931_9PSEU/4-222---GGPVLLIRSLAARLTAELL
D7GS63_9FIRM/4-220---QKPVLLSRTLVARVIRELV
A8I8Z9_AZOC5/6-223---KGPVVLGIATAARIVEELL
A7MLX0_CROS8/5-224---DVPVLLSNVLVARLASELL
E3HTW6_ACHXA/8-227---GRPVLLSNRMVAQALAQIL
G2NY32_STRVO/21-248---GRPVLLARAIAVRMAAEVV
B2VIS4_ERWT9/6-224---GIPVLLPNTLVVKLAAEVL
Q89Q90_BRADU/10-227---PGPAILGIAAAARIVEELV
R5F3Q4_9CLOT/6-223---GKPVILPRSFLAGVIRE..
U5RP12_9CLOT/5-223---GKPVILPRTLIGRIIKEML
AROM_ECOLI/5-224---DVPVLLSNVLIARLAAELL
C6WHA6_ACTMD/11-233---GVPVVLARSVVARLAAELL
W0I3S6_9ENTR/6-226---ALPVLLANQLLADLMRNLL
D5CIT0_ENTCC/5-224---DVPVLLSNVLMARLASELL
R9VV20_9ENTR/5-224---DVPVLLSNVLAARLASELL
E6W7U6_PANSA/7-224---GIPVLLSNVLVAKLAAELI
D4J4L6_9FIRM/6-224---GLPVLLPRTLVVRILCEMF
D4GS98_HALVD/4-219---GTGVLLGRSVLAKTAEEVL
D7B4S5_NOCDD/4-224---GLPVVLARSVCVRLASEVL
Q0K9C3_CUPNH/11-227---GAPVLLSNRMVARLLGQVL
R5PRJ6_9BURK/4-224---DVPVIASSTMVAELTANLL
R6RFN0_9CLOT/4-219---GKSVLLPRTLAARVVKEL.
R5C719_9FIRM/6-224---GLPVILPRTFIARLLNEMF
Q11H78_CHESB/5-216---HKPVVTARRVIAGAL....
D8MM34_ERWBE/6-226---DLPVILSNQLLADLLRNLL
E3F5F1_KETVY/9-222---GRRVLLARKIVASALQLLL
A6T5B5_KLEP7/6-225---DVPVLLSNVLVSRLAAELL
R7D8J2_9FIRM/3-222---GKKVVLPRTLLARVVSELT
Q8ZRE8_SALTY/5-224---DVPVLLSNVLIARLASELL
D1AMF6_SEBTE/5-223---GKPVVLSRTMVARVASELT
D1C485_SPHTD/4-219---GVPTILANRLVGRVVEEIV
H3ZPE7_THELN/3-216---KTPVVLPRTLMARVIGELL
H2IZN8_RAHAC/5-224---NIPVLLPNVLMAKLAAELV
A8GAI9_SERP5/5-224---EIPVLLSNALVAKLAAELI
A8MB15_CALMQ/7-221---KKPIILPRTLLVRVIKELL
Q5WKI2_BACSK/4-216---GLPVILARSAVARAAAEL.
R5XQZ3_9FIRM/3-222---GKKVVLPRTLLARVVSELT
D7CE98_STRBB/6-233---GRPVLLARAIAVRMAGEVV
Q2RLZ2_MOOTA/5-222---GIPVILPRAVAARTLIELV
F0JK91_DESDE/7-227---GIATLNATSIMARALQELM

PF14669

TOPZ1_RAT/1220-1454-----DVLHRHNLLCAI-----

This alignment is coloured according to the ClustalX colouring scheme:

 
Glycine (G)
 
Proline (P)
 
Small or hydrophobic (C,A,V,L,I,M,F,W)
 
Hydroxyl or amine amino acids (S,T,N,Q)
 
Charged amino-acids (D,E,R,K)
 
Histidine or tyrosine (H,Y)

For UniProt-based alignments, we also add some additional mark-up to the alignments where appropriate. Active site information is shown as follows:

 
Active site (residue annotated in SwissProt as an active site)
 
Predicted active site (residue aligns in a Pfam alignment with a SwissProt active site)
 
Predicted active site (residue annotated in SwissProt as a potential active site)

Some UniProt sequences can be mapped to protein structures, in which case we also show the secondary structure definition. These lines are shown below the sequence to which they apply and are marked (SS). The meaning of each of the symbols is as follows:

C
Random coil
H
Alpha-helix
G
3(10) helix
I
Pi-helix
E
Hydrogen bonded beta-strand (extended strand)
B
Residue in isolated beta-bridge
T
H-bonded turn (3-turn, 4-turn, or 5-turn)
S
Bend (five-residue bend centered at residue i)
Close window